| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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| Icatibant | hsa00071 | Fatty acid degradation | 4.66E-02 | 3 | O75521, P11766, P33121 | ECI2, ADH5, ACSL1 | More | | | Icatibant | hsa00190 | Oxidative phosphorylation | 2.21E-02 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Icatibant | hsa00280 | Valine, leucine and isoleucine degradation | 1.67E-02 | 4 | P55809, Q9HCC0, Q02252, P11310 | OXCT1, MCCC2, ALDH6A1, ACADM | More | | | Icatibant | hsa00480 | Glutathione metabolism | 3.02E-02 | 1 | P48506 | GCLC | More | | | Icatibant | hsa00500 | Starch and sucrose metabolism | 9.22E-04 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Icatibant | hsa00561 | Glycerolipid metabolism | 2.21E-02 | 3 | O14494, P06280, P23743 | PLPP1, GLA, DGKA | More | | | Icatibant | hsa00600 | Sphingolipid metabolism | 3.96E-02 | 3 | Q9BX95, O14494, P06280 | SGPP1, PLPP1, GLA | More | | | Icatibant | hsa00730 | Thiamine metabolism | 4.66E-02 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Icatibant | hsa00770 | Pantothenate and CoA biosynthesis | 7.90E-03 | 3 | O95498, O95497, Q9NRN7 | VNN2, VNN1, AASDHPPT | More | | | Icatibant | hsa00970 | Aminoacyl-tRNA biosynthesis | 1.58E-04 | 4 | O95363, P54136, P14868, Q15046 | FARS2, RARS1, DARS, KARS | More | | | Icatibant | hsa01210 | 2-Oxocarboxylic acid metabolism | 3.43E-02 | 1 | P50213 | IDH3A | More | | | Icatibant | hsa02010 | ABC transporters | 3.76E-02 | 1 | Q99758 | ABCA3 | More | | | Icatibant | hsa03013 | RNA transport | 2.00E-02 | 11 | O14980, P52298, Q09161, P61326, Q7Z3B4, P35658, P47813, Q14152, O75822, Q14240, Q9Y6A5 | XPO1, NCBP2, NCBP1, MAGOH, NUP54, NUP214, EIF1AX, EIF3A, EIF3J, EIF4A2, TACC3 | More | | | Icatibant | hsa03018 | RNA degradation | 3.02E-02 | 1 | Q13901 | C1D | More | | | Icatibant | hsa04062 | Chemokine signaling pathway | 3.93E-03 | 10 | P25024, P25025, P47992, Q9UBD3, P07948, P63218, P50151, P49407, Q08881, P49841 | CXCR1, CXCR2, XCL1, XCL2, LYN, GNG5, GNG10, ARRB1, ITK, GSK3B | More | | | Icatibant | hsa04071 | Sphingolipid signaling pathway | 1.94E-02 | 6 | Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2 | EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2 | More | | | Icatibant | hsa04141 | Protein processing in endoplasmic reticulum | 2.78E-02 | 3 | P07384, O95487, O95816 | CAPN1, SEC24B, BAG2 | More | | | Icatibant | hsa04144 | Endocytosis | 4.10E-02 | 3 | O75351, P62491, Q14161 | VPS4B, RAB11A, GIT2 | More | | | Icatibant | hsa04145 | Phagosome | 3.94E-02 | 6 | P60709, Q15075, Q15080, P14598, Q13509, Q13488 | ACTB, EEA1, NCF4, NCF1, TUBB3, TCIRG1 | More | | | Icatibant | hsa04216 | Ferroptosis | 4.50E-02 | 1 | P48506 | GCLC | More | | | Icatibant | hsa04340 | Hedgehog signaling pathway | 1.80E-02 | 4 | P49841, P22694, Q13635, P10415 | GSK3B, PRKACB, PTCH1, BCL2 | More | | | Icatibant | hsa04350 | TGF-beta signaling pathway | 4.88E-02 | 1 | P37173 | TGFBR2 | More | | | Icatibant | hsa04360 | Axon guidance | 1.50E-02 | 3 | P20827, P23528, Q06124 | EFNA1, CFL1, PTPN11 | More | | | Icatibant | hsa04530 | Tight junction | 2.08E-02 | 3 | P63261, Q9Y478, Q92974 | ACTG1, PRKAB1, ARHGEF2 | More | | | Icatibant | hsa04612 | Antigen processing and presentation | 1.51E-02 | 7 | P13765, P48382, P26715, P26717, Q13241, O43908, P01732 | HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A | More | | | Icatibant | hsa04614 | Renin-angiotensin system | 1.52E-02 | 1 | P50052 | AGTR2 | More | | | Icatibant | hsa04650 | Natural killer cell mediated cytotoxicity | 7.01E-05 | 10 | P01375, P78314, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715 | TNF, SH3BP2, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | | Icatibant | hsa04657 | IL-17 signaling pathway | 3.91E-02 | 7 | O00463, Q16539, P49841, P09341, P14780, P80188, P01375 | TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF | More | | | Icatibant | hsa04660 | T cell receptor signaling pathway | 1.49E-03 | 10 | P01375, O95267, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841 | TNF, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3B | More | | | Icatibant | hsa04714 | Thermogenesis | 1.25E-02 | 3 | P15336, P63261, Q9Y478 | ATF2, ACTG1, PRKAB1 | More | | | Icatibant | hsa04728 | Dopaminergic synapse | 2.82E-02 | 6 | P14416, P63218, P50151, P49841, Q16539, P49407 | DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1 | More | | | Icatibant | hsa04920 | Adipocytokine signaling pathway | 2.80E-02 | 2 | Q06124, Q9Y478 | PTPN11, PRKAB1 | More | | | Icatibant | hsa04924 | Renin secretion | 3.64E-02 | 3 | P22694, P07550, Q14643 | PRKACB, ADRB2, ITPR1 | More | | | Icatibant | hsa04962 | Vasopressin-regulated water reabsorption | 1.80E-02 | 2 | P62491, P46459 | RAB11A, NSF | More | | | Icatibant | hsa05110 | Vibrio cholerae infection | 4.50E-03 | 4 | Q13488, P17252, P19174, P60709 | TCIRG1, PRKCA, PLCG1, ACTB | More | | | Icatibant | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 3.11E-02 | 4 | Q16539, P25024, P25025, P07948 | MAPK14, CXCR1, CXCR2, LYN | More | | | Icatibant | hsa05130 | Pathogenic Escherichia coli infection | 9.80E-03 | 4 | Q92974, P63261, Q06124, O95487 | ARHGEF2, ACTG1, PTPN11, SEC24B | More | | | Icatibant | hsa05135 | Yersinia infection | 4.65E-02 | 5 | P13612, P06239, Q16539, P01375, P49841 | ITGA4, LCK, MAPK14, TNF, GSK3B | More | | | Icatibant | hsa05140 | Leishmaniasis | 2.45E-03 | 11 | P13612, O75015, P14598, P42224, P13765, O60603, P25963, P01375, P29350, Q16539, Q15080 | ITGA4, FCGR3B, NCF1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, PTPN6, MAPK14, NCF4 | More | | | Icatibant | hsa05144 | Malaria | 1.32E-05 | 5 | P60033, O60603, P01375, P35443, P26718 | CD81, TLR2, TNF, THBS4, KLRK1 | More | | | Icatibant | hsa05146 | Amoebiasis | 3.91E-02 | 7 | P09341, P27930, P01375, O60603, P05089, P22694, P08311 | CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSG | More | | | Icatibant | hsa05163 | Human cytomegalovirus infection | 1.72E-02 | 8 | P01375, P63218, P50151, P49841, P14778, P25025, Q16539, O00463 | TNF, GNG5, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5 | More | | | Icatibant | hsa05211 | Renal cell carcinoma | 1.06E-02 | 2 | Q06124, Q99814 | PTPN11, EPAS1 | More | | | Icatibant | hsa05212 | Pancreatic cancer | 3.40E-02 | 1 | P37173 | TGFBR2 | More | | | Icatibant | hsa05223 | Non-small cell lung cancer | 3.99E-02 | 4 | P17252, O43524, P19174, O75293 | PRKCA, FOXO3, PLCG1, GADD45B | More | | | Icatibant | hsa05231 | Choline metabolism in cancer | 3.99E-02 | 4 | P19174, P23743, O14494, P17252 | PLCG1, DGKA, PLPP1, PRKCA | More | | | Icatibant | hsa05310 | Asthma | 2.81E-02 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | | Icatibant | hsa05321 | Inflammatory bowel disease | 2.40E-03 | 5 | O60603, P01375, P13765, Q14765, Q9UL17 | TLR2, TNF, HLA-DOB, STAT4, TBX21 | More | | | Icatibant | hsa05332 | Graft-versus-host disease | 1.40E-03 | 5 | P13765, P10747, P01375, P26715, Q13241 | HLA-DOB, CD28, TNF, KLRC1, KLRD1 | More | | | Icatibant | hsa05415 | Diabetic cardiomyopathy | 3.94E-02 | 6 | P17252, P14598, Q15080, Q16718, O14521, P04406 | PRKCA, NCF1, NCF4, NDUFA5, SDHD, GAPDH | More | | | Icatibant | hsa05418 | Fluid shear stress and atherosclerosis | 3.61E-02 | 6 | Q16539, P10599, P14780, P01375, P14778, P27930 | MAPK14, TXN, MMP9, TNF, IL1R1, IL1R2 | More | |
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