PharmaCoNets of Hydrocortisone-phosphate (SPCN: 42.91 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Hydrocortisone-phosphatehsa00030Pentose phosphate pathway8.97E-031P11413G6PDMore
Hydrocortisone-phosphatehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Hydrocortisone-phosphatehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Hydrocortisone-phosphatehsa00220Arginine biosynthesis1.94E-033P15104, P05089, P49448GLUL, ARG1, GLUD2More
Hydrocortisone-phosphatehsa00250Alanine, aspartate and glutamate metabolism4.32E-022P49448, P15104GLUD2, GLULMore
Hydrocortisone-phosphatehsa00480Glutathione metabolism1.35E-021P11413G6PDMore
Hydrocortisone-phosphatehsa00500Starch and sucrose metabolism7.23E-053O43451, P46976, P06737MGAM, GYG1, PYGLMore
Hydrocortisone-phosphatehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Hydrocortisone-phosphatehsa00730Thiamine metabolism6.40E-042P05186, P24666ALPL, ACP1More
Hydrocortisone-phosphatehsa00910Nitrogen metabolism4.32E-022P15104, P49448GLUL, GLUD2More
Hydrocortisone-phosphatehsa00970Aminoacyl-tRNA biosynthesis1.21E-021P14868DARSMore
Hydrocortisone-phosphatehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Hydrocortisone-phosphatehsa01200Carbon metabolism2.91E-021P11413G6PDMore
Hydrocortisone-phosphatehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Hydrocortisone-phosphatehsa03013RNA transport3.11E-022P68104, Q14232EEF1A1, EIF2B1More
Hydrocortisone-phosphatehsa04061Viral protein interaction with cytokine and cytokine receptor2.00E-027P09341, P25024, P25025, P47992, Q9UBD3, Q13651, P01375CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RA, TNFMore
Hydrocortisone-phosphatehsa04062Chemokine signaling pathway3.13E-028P25024, P25025, P07948, P42338, P63218, P50151, P49407, P49841CXCR1, CXCR2, LYN, PIK3CB, GNG5, GNG10, ARRB1, GSK3BMore
Hydrocortisone-phosphatehsa04064NF-kappa B signaling pathway4.58E-034Q13489, Q13546, Q9UDY8, Q9UNE0BIRC3, RIPK1, MALT1, EDARMore
Hydrocortisone-phosphatehsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Hydrocortisone-phosphatehsa04140Autophagy - animal3.61E-025Q9NQL2, P22694, Q14643, Q9H1Y0, Q04759RRAGD, PRKACB, ITPR1, ATG5, PRKCQMore
Hydrocortisone-phosphatehsa04141Protein processing in endoplasmic reticulum3.89E-022P17861, Q9NR31XBP1, SAR1AMore
Hydrocortisone-phosphatehsa04150mTOR signaling pathway2.72E-024P42338, Q9NQL2, Q13322, P49841PIK3CB, RRAGD, GRB10, GSK3BMore
Hydrocortisone-phosphatehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Hydrocortisone-phosphatehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Hydrocortisone-phosphatehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Hydrocortisone-phosphatehsa04217Necroptosis2.93E-023P01568, Q13489, Q13546IFNA21, BIRC3, RIPK1More
Hydrocortisone-phosphatehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Hydrocortisone-phosphatehsa04380Osteoclast differentiation4.71E-026Q16539, P06239, P42338, P14778, O75015, Q8N149MAPK14, LCK, PIK3CB, IL1R1, FCGR3B, LILRA2More
Hydrocortisone-phosphatehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Hydrocortisone-phosphatehsa04612Antigen processing and presentation3.60E-038P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Hydrocortisone-phosphatehsa04613Neutrophil extracellular trap formation6.66E-0415P11215, O60603, P05164, P08246, Q9UM07, Q13547, P58876, Q16778, O60814, P20160, P08311, O75015, P21730, O43315, Q16539ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2BC5, HIST2H2BE, H2BC12, AZU1, CTSG, FCGR3B, C5AR1, AQP9, MAPK14More
Hydrocortisone-phosphatehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Hydrocortisone-phosphatehsa04621NOD-like receptor signaling pathway3.13E-0417Q16539, Q14643, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, Q13546, P29728, Q05823, P01375, P09341, P49913, P59665, P59666, P12838MAPK14, ITPR1, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, RIPK1, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Hydrocortisone-phosphatehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Hydrocortisone-phosphatehsa04623Cytosolic DNA-sensing pathway2.20E-032P01568, Q13546IFNA21, RIPK1More
Hydrocortisone-phosphatehsa04640Hematopoietic cell lineage1.10E-029P13612, P14778, P27930, P15144, P25063, P09693, P01732, P13765, P01375ITGA4, IL1R1, IL1R2, ANPEP, CD24, CD3G, CD8A, HLA-DOB, TNFMore
Hydrocortisone-phosphatehsa04650Natural killer cell mediated cytotoxicity3.11E-049P01375, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Hydrocortisone-phosphatehsa04657IL-17 signaling pathway1.80E-037O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Hydrocortisone-phosphatehsa04658Th1 and Th2 cell differentiation5.29E-0612Q04759, P07766, P20963, P09693, Q16539, P01730, P06239, Q14765, P23771, Q9UL17, P13765, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, CD4, LCK, STAT4, GATA3, TBX21, HLA-DOB, RUNX3More
Hydrocortisone-phosphatehsa04659Th17 cell differentiation1.31E-0411Q04759, Q16539, P01730, P06239, P13765, P14778, Q9UL17, P23771, P07766, P09693, P20963PRKCQ, MAPK14, CD4, LCK, HLA-DOB, IL1R1, TBX21, GATA3, CD3E, CD3G, CD247More
Hydrocortisone-phosphatehsa04660T cell receptor signaling pathway6.26E-0514P01375, Q04759, P42338, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841TNF, PRKCQ, PIK3CB, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Hydrocortisone-phosphatehsa04662B cell receptor signaling pathway2.80E-036P49841, P42338, P60033, P07948, P21854, Q8N149GSK3B, PIK3CB, CD81, LYN, CD72, LILRA2More
Hydrocortisone-phosphatehsa04664Fc epsilon RI signaling pathway1.80E-024Q16539, P42338, P07948, P09917MAPK14, PIK3CB, LYN, ALOX5More
Hydrocortisone-phosphatehsa04723Retrograde endocannabinoid signaling3.86E-024P63218, P50151, P48058, Q16539GNG5, GNG10, GRIA4, MAPK14More
Hydrocortisone-phosphatehsa04724Glutamatergic synapse7.09E-035P48058, P43003, P63218, P50151, P15104GRIA4, SLC1A3, GNG5, GNG10, GLULMore
Hydrocortisone-phosphatehsa04728Dopaminergic synapse2.35E-026P63218, P50151, P49841, Q16539, P49407, P48058GNG5, GNG10, GSK3B, MAPK14, ARRB1, GRIA4More
Hydrocortisone-phosphatehsa04750Inflammatory mediator regulation of TRP channels3.61E-025P14778, P22694, Q16539, Q14643, Q04759IL1R1, PRKACB, MAPK14, ITPR1, PRKCQMore
Hydrocortisone-phosphatehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Hydrocortisone-phosphatehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Hydrocortisone-phosphatehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Hydrocortisone-phosphatehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Hydrocortisone-phosphatehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Hydrocortisone-phosphatehsa04973Carbohydrate digestion and absorption1.57E-022O43451, P42338MGAM, PIK3CBMore
Hydrocortisone-phosphatehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Hydrocortisone-phosphatehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Hydrocortisone-phosphatehsa05010Alzheimer disease1.01E-023Q06055, P17861, P62195ATP5G2, XBP1, PSMC5More
Hydrocortisone-phosphatehsa05012Parkinson disease5.41E-033Q06055, P17861, P62195ATP5G2, XBP1, PSMC5More
Hydrocortisone-phosphatehsa05014Amyotrophic lateral sclerosis1.01E-023Q06055, P17861, P62195ATP5G2, XBP1, PSMC5More
Hydrocortisone-phosphatehsa05017Spinocerebellar ataxia1.42E-022P17861, P62195XBP1, PSMC5More
Hydrocortisone-phosphatehsa05022Pathways of neurodegeneration - multiple diseases1.66E-023Q06055, P17861, P62195ATP5G2, XBP1, PSMC5More
Hydrocortisone-phosphatehsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Hydrocortisone-phosphatehsa05120Epithelial cell signaling in Helicobacter pylori infection2.72E-024Q16539, P25024, P25025, P07948MAPK14, CXCR1, CXCR2, LYNMore
Hydrocortisone-phosphatehsa05132Salmonella infection9.85E-034Q13546, Q13489, O60282, P68371RIPK1, BIRC3, KIF5C, TUBB2CMore
Hydrocortisone-phosphatehsa05133Pertussis4.20E-021P0C0L4C4AMore
Hydrocortisone-phosphatehsa05134Legionellosis5.53E-032Q9NR31, P68104SAR1A, EEF1A1More
Hydrocortisone-phosphatehsa05135Yersinia infection1.11E-038P13612, P06239, Q16539, P01375, P42338, P49841, P01730, P01732ITGA4, LCK, MAPK14, TNF, PIK3CB, GSK3B, CD4, CD8AMore
Hydrocortisone-phosphatehsa05140Leishmaniasis2.69E-026P13612, O75015, P13765, O60603, P01375, Q16539ITGA4, FCGR3B, HLA-DOB, TLR2, TNF, MAPK14More
Hydrocortisone-phosphatehsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Hydrocortisone-phosphatehsa05144Malaria9.96E-057P60033, P69905, P68871, O60603, P01375, P35443, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Hydrocortisone-phosphatehsa05146Amoebiasis5.94E-049P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSGMore
Hydrocortisone-phosphatehsa05150Staphylococcus aureus infection1.02E-037P21730, P21462, O75015, P59665, P59666, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Hydrocortisone-phosphatehsa05163Human cytomegalovirus infection3.60E-0412P42338, P01375, P63218, P50151, Q14643, P22694, P49841, P14778, Q13651, P25025, Q16539, O00463PIK3CB, TNF, GNG5, GNG10, ITPR1, PRKACB, GSK3B, IL1R1, IL10RA, CXCR2, MAPK14, TRAF5More
Hydrocortisone-phosphatehsa05169Epstein-Barr virus infection2.32E-029Q13547, O00463, Q16539, P42338, P07948, Q13761, P24522, P07766, P20963HDAC1, TRAF5, MAPK14, PIK3CB, LYN, RUNX3, GADD45A, CD3E, CD247More
Hydrocortisone-phosphatehsa05202Transcriptional misregulation in cancer4.29E-0313P14780, P27930, Q15744, Q16548, P11215, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522MMP9, IL1R2, CEBPE, BCL2A1, ITGAM, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45AMore
Hydrocortisone-phosphatehsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Hydrocortisone-phosphatehsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
Hydrocortisone-phosphatehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer5.53E-0410P42338, O95267, P07766, P20963, P09693, P06239, O60603, Q04759, Q16539, P01730PIK3CB, RASGRP1, CD3E, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14, CD4More
Hydrocortisone-phosphatehsa05310Asthma1.62E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Hydrocortisone-phosphatehsa05321Inflammatory bowel disease1.09E-036O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Hydrocortisone-phosphatehsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Hydrocortisone-phosphatehsa05332Graft-versus-host disease1.76E-024P13765, P01375, P26715, Q13241HLA-DOB, TNF, KLRC1, KLRD1More
Hydrocortisone-phosphatehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Hydrocortisone-phosphatehsa05415Diabetic cardiomyopathy3.59E-021P11413G6PDMore

Community members of Hydrocortisone-phosphate (SDC: 3.72)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)