PharmaCoNets of Hexylresorcinol (SPCN: 45.10 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Hexylresorcinolhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Hexylresorcinolhsa00220Arginine biosynthesis1.58E-022P05089, P49448ARG1, GLUD2More
Hexylresorcinolhsa00340Histidine metabolism4.52E-021O95954FTCDMore
Hexylresorcinolhsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Hexylresorcinolhsa00564Glycerophospholipid metabolism9.70E-032Q9Y259, P49619CHKB, DGKGMore
Hexylresorcinolhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Hexylresorcinolhsa00830Retinol metabolism1.13E-023P11766, P00352, Q9BPW9ADH5, ALDH1A1, DHRS9More
Hexylresorcinolhsa00920Sulfur metabolism3.18E-021Q16762TSTMore
Hexylresorcinolhsa00970Aminoacyl-tRNA biosynthesis3.78E-022O95363, Q15046FARS2, KARSMore
Hexylresorcinolhsa01100Metabolic pathways2.25E-027Q9Y259, Q13956, P49619, O95954, Q02318, Q9UBX8, P35573CHKB, PDE6H, DGKG, FTCD, CYP27A1, B4GALT6, AGLMore
Hexylresorcinolhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Hexylresorcinolhsa01522Endocrine resistance2.16E-021P04049RAF1More
Hexylresorcinolhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Hexylresorcinolhsa03040Spliceosome1.28E-0513O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Hexylresorcinolhsa03320PPAR signaling pathway1.62E-022Q13133, Q02318NR1H3, CYP27A1More
Hexylresorcinolhsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Hexylresorcinolhsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Hexylresorcinolhsa04014Ras signaling pathway1.13E-029P04049, P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174RAF1, PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1More
Hexylresorcinolhsa04015Rap1 signaling pathway8.30E-0412P04049, P20827, P49767, Q96FS4, P11215, P25116, Q8TEU7, Q13009, Q7LDG7, P42338, P08514, P19174RAF1, EFNA1, VEGFC, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, RASGRP2, PIK3CB, ITGA2B, PLCG1More
Hexylresorcinolhsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Hexylresorcinolhsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Hexylresorcinolhsa04062Chemokine signaling pathway3.64E-0311P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, P04049, Q8WYR1FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, RAF1, PIK3R5More
Hexylresorcinolhsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Hexylresorcinolhsa04071Sphingolipid signaling pathway2.16E-021P04049RAF1More
Hexylresorcinolhsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Hexylresorcinolhsa04110Cell cycle3.57E-023Q9UBD5, P06493, P33981ORC3, CDK1, TTKMore
Hexylresorcinolhsa04122Sulfur relay system3.18E-021Q16762TSTMore
Hexylresorcinolhsa04140Autophagy - animal2.82E-021P04049RAF1More
Hexylresorcinolhsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Hexylresorcinolhsa04151PI3K-Akt signaling pathway3.70E-0212P42338, P43657, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, P30281PIK3CB, P2RY5, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, CCND3More
Hexylresorcinolhsa04210Apoptosis2.16E-021P04049RAF1More
Hexylresorcinolhsa04218Cellular senescence2.49E-021P04049RAF1More
Hexylresorcinolhsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Hexylresorcinolhsa04360Axon guidance1.51E-027P16333, P20827, O95631, P42338, P07332, P04049, P19174NCK1, EFNA1, NTN1, PIK3CB, FES, RAF1, PLCG1More
Hexylresorcinolhsa04370VEGF signaling pathway8.29E-031P04049RAF1More
Hexylresorcinolhsa04371Apelin signaling pathway4.16E-038P63218, P50151, Q8WYR1, P04049, Q14814, Q14344, Q13485, P84022GNG5, GNG10, PIK3R5, RAF1, MEF2D, GNA13, SMAD4, SMAD3More
Hexylresorcinolhsa04510Focal adhesion3.48E-021P04049RAF1More
Hexylresorcinolhsa04512ECM-receptor interaction3.73E-022P07359, P08514GP1BA, ITGA2BMore
Hexylresorcinolhsa04514Cell adhesion molecules8.19E-033P16109, P56750, O00501SELP, CLDN17, CLDN5More
Hexylresorcinolhsa04530Tight junction1.38E-045Q8TEU7, P16989, P56750, O00501, Q14247RAPGEF6, CSDA, CLDN17, CLDN5, CTTNMore
Hexylresorcinolhsa04540Gap junction1.33E-021P04049RAF1More
Hexylresorcinolhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Hexylresorcinolhsa04610Complement and coagulation cascades1.03E-033P25116, P09871, P0C0L4F2R, C1S, C4AMore
Hexylresorcinolhsa04611Platelet activation5.18E-055P25116, P08514, Q15746, Q8WYR1, P07359F2R, ITGA2B, MYLK, PIK3R5, GP1BAMore
Hexylresorcinolhsa04613Neutrophil extracellular trap formation2.81E-035P04049, P16109, O60814, P08514, P07359RAF1, SELP, H2BC12, ITGA2B, GP1BAMore
Hexylresorcinolhsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Hexylresorcinolhsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Hexylresorcinolhsa04650Natural killer cell mediated cytotoxicity1.82E-021P04049RAF1More
Hexylresorcinolhsa04658Th1 and Th2 cell differentiation3.24E-024P09693, Q16539, P01730, P23771CD3G, MAPK14, CD4, GATA3More
Hexylresorcinolhsa04659Th17 cell differentiation1.70E-027P19174, P14784, P14778, P84022, Q13485, P08238, P07766PLCG1, IL2RB, IL1R1, SMAD3, SMAD4, HSP90AB1, CD3EMore
Hexylresorcinolhsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Hexylresorcinolhsa04662B cell receptor signaling pathway2.42E-036P42338, P60033, P07948, P21854, Q8N149, P04049PIK3CB, CD81, LYN, CD72, LILRA2, RAF1More
Hexylresorcinolhsa04664Fc epsilon RI signaling pathway5.86E-035P42338, P07948, P19174, P04049, P09917PIK3CB, LYN, PLCG1, RAF1, ALOX5More
Hexylresorcinolhsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Hexylresorcinolhsa04720Long-term potentiation1.66E-021P04049RAF1More
Hexylresorcinolhsa04722Neurotrophin signaling pathway2.32E-021P04049RAF1More
Hexylresorcinolhsa04726Serotonergic synapse1.33E-021P04049RAF1More
Hexylresorcinolhsa04730Long-term depression1.16E-021P04049RAF1More
Hexylresorcinolhsa04810Regulation of actin cytoskeleton7.86E-034Q15746, P04049, P08514, P25116MYLK, RAF1, ITGA2B, F2RMore
Hexylresorcinolhsa04910Insulin signaling pathway1.49E-021P04049RAF1More
Hexylresorcinolhsa04912GnRH signaling pathway1.82E-021P04049RAF1More
Hexylresorcinolhsa04914Progesterone-mediated oocyte maturation2.16E-021P04049RAF1More
Hexylresorcinolhsa04915Estrogen signaling pathway2.99E-021P04049RAF1More
Hexylresorcinolhsa04916Melanogenesis1.33E-021P04049RAF1More
Hexylresorcinolhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Hexylresorcinolhsa04919Thyroid hormone signaling pathway1.82E-021P04049RAF1More
Hexylresorcinolhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Hexylresorcinolhsa04926Relaxin signaling pathway2.32E-021P04049RAF1More
Hexylresorcinolhsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Hexylresorcinolhsa04929GnRH secretion4.98E-031P04049RAF1More
Hexylresorcinolhsa04933AGE-RAGE signaling pathway in diabetic complications3.21E-025P84022, Q13485, P42338, P49767, P19174SMAD3, SMAD4, PIK3CB, VEGFC, PLCG1More
Hexylresorcinolhsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Hexylresorcinolhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Hexylresorcinolhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Hexylresorcinolhsa05034Alcoholism2.49E-021P04049RAF1More
Hexylresorcinolhsa05120Epithelial cell signaling in Helicobacter pylori infection3.29E-023Q16539, P09341, P25024MAPK14, CXCL1, CXCR1More
Hexylresorcinolhsa05130Pathogenic Escherichia coli infection7.39E-034Q14247, P56750, O00501, P25116CTTN, CLDN17, CLDN5, F2RMore
Hexylresorcinolhsa05132Salmonella infection4.98E-021P04049RAF1More
Hexylresorcinolhsa05133Pertussis1.86E-033P09871, P0C0L4, Q02556C1S, C4A, IRF8More
Hexylresorcinolhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Hexylresorcinolhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Hexylresorcinolhsa05152Tuberculosis3.98E-021P04049RAF1More
Hexylresorcinolhsa05160Hepatitis C1.99E-021P04049RAF1More
Hexylresorcinolhsa05161Hepatitis B1.99E-021P04049RAF1More
Hexylresorcinolhsa05163Human cytomegalovirus infection4.98E-021P04049RAF1More
Hexylresorcinolhsa05164Influenza A3.65E-021P04049RAF1More
Hexylresorcinolhsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Hexylresorcinolhsa05170Human immunodeficiency virus 1 infection3.48E-021P04049RAF1More
Hexylresorcinolhsa05200Pathways in cancer9.46E-0317Q13751, P42338, P08238, P19174, P43246, P84022, Q13485, Q13547, P30281, P49767, P43657, P63218, P50151, Q14344, Q7LDG7, O75293, P14784LAMB3, PIK3CB, HSP90AB1, PLCG1, MSH2, SMAD3, SMAD4, HDAC1, CCND3, VEGFC, P2RY5, GNG5, GNG10, GNA13, RASGRP2, GADD45B, IL2RBMore
Hexylresorcinolhsa05205Proteoglycans in cancer3.48E-021P04049RAF1More
Hexylresorcinolhsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Hexylresorcinolhsa05210Colorectal cancer1.66E-021P04049RAF1More
Hexylresorcinolhsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Hexylresorcinolhsa05212Pancreatic cancer8.83E-035P42338, P04049, P84022, Q13485, O75293PIK3CB, RAF1, SMAD3, SMAD4, GADD45BMore
Hexylresorcinolhsa05213Endometrial cancer9.95E-031P04049RAF1More
Hexylresorcinolhsa05214Glioma9.95E-031P04049RAF1More
Hexylresorcinolhsa05215Prostate cancer1.33E-021P04049RAF1More
Hexylresorcinolhsa05218Melanoma6.63E-031P04049RAF1More
Hexylresorcinolhsa05219Bladder cancer4.98E-031P04049RAF1More
Hexylresorcinolhsa05220Chronic myeloid leukemia3.00E-036Q13547, Q13485, P84022, P42338, P04049, O75293HDAC1, SMAD4, SMAD3, PIK3CB, RAF1, GADD45BMore
Hexylresorcinolhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Hexylresorcinolhsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Hexylresorcinolhsa05224Breast cancer1.49E-021P04049RAF1More
Hexylresorcinolhsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Hexylresorcinolhsa05226Gastric cancer8.29E-031P04049RAF1More
Hexylresorcinolhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Hexylresorcinolhsa05231Choline metabolism in cancer1.55E-033P04049, Q9Y259, P49619RAF1, CHKB, DGKGMore
Hexylresorcinolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Hexylresorcinolhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More

Community members of Hexylresorcinol (SDC: 3.29)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P18054ALOX12Polyunsaturated fatty acid lipoxygenase ALOX12Predicted00.00750.37030.24160.986
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P11388TOP2ADNA topoisomerase 2NonealphaPredicted00.19920.46590.19271.2242
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
P16452EPB42Protein 4.2Predicted00.09470.002200.0517
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)