| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Halofantrine | hsa00220 | Arginine biosynthesis | 1.97E-02 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Halofantrine | hsa00250 | Alanine, aspartate and glutamate metabolism | 1.97E-02 | 2 | P49448, P15104 | GLUD2, GLUL | More | | | Halofantrine | hsa00910 | Nitrogen metabolism | 1.97E-02 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Halofantrine | hsa04151 | PI3K-Akt signaling pathway | 3.96E-02 | 8 | P43657, P09603, Q9GZP0, P63218, P50151, P13612, O15335, Q13751 | P2RY5, CSF1, PDGFD, GNG5, GNG10, ITGA4, CHAD, LAMB3 | More | | | Halofantrine | hsa04512 | ECM-receptor interaction | 4.41E-02 | 3 | Q13751, P13612, O15335 | LAMB3, ITGA4, CHAD | More | | | Halofantrine | hsa04724 | Glutamatergic synapse | 9.51E-03 | 4 | O15399, P63218, P50151, P15104 | GRIN2D, GNG5, GNG10, GLUL | More | | | Halofantrine | hsa04727 | GABAergic synapse | 2.33E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Halofantrine | hsa04730 | Long-term depression | 3.72E-02 | 2 | Q14344, P07948 | GNA13, LYN | More | | | Halofantrine | hsa05010 | Alzheimer disease | 4.39E-02 | 6 | O15399, Q9NZJ5, Q13564, Q71U36, P09603, P21796 | GRIN2D, EIF2AK3, APPBP1, TUBA1A, CSF1, VDAC1 | More | | | Halofantrine | hsa05032 | Morphine addiction | 1.34E-02 | 4 | P63218, P50151, Q07343, P43250 | GNG5, GNG10, PDE4B, GRK6 | More | |
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