PharmaCoNets of Guaiacol (SPCN: 12.62 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Guaiacolhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Guaiacolhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Guaiacolhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Guaiacolhsa03010Ribosome1.88E-026P62753, P25398, P32969, P62829, P18077, P36578RPS6, RPS12, RPL9, RPL23, RPL35A, RPL4More
Guaiacolhsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Guaiacolhsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Guaiacolhsa04071Sphingolipid signaling pathway1.87E-026Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Guaiacolhsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Guaiacolhsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Guaiacolhsa04217Necroptosis4.42E-046P07900, P15104, P05141, P01584, P0C0S5, Q13557HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, CAMK2DMore
Guaiacolhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Guaiacolhsa04613Neutrophil extracellular trap formation7.32E-0313O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Guaiacolhsa04657IL-17 signaling pathway3.87E-038P07900, O00463, Q16539, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Guaiacolhsa04932Non-alcoholic fatty liver disease9.70E-034P18848, P01584, P13073, O15239ATF4, IL1B, COX4I1, NDUFA1More
Guaiacolhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Guaiacolhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Guaiacolhsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Guaiacolhsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Guaiacolhsa05020Prion disease3.37E-037P13591, P01584, P11142, O15239, P13073, P18848, P05141NCAM1, IL1B, HSPA8, NDUFA1, COX4I1, ATF4, SLC25A5More
Guaiacolhsa05022Pathways of neurodegeneration - multiple diseases3.80E-026O15239, P13073, P18848, P05141, P01584, Q13557NDUFA1, COX4I1, ATF4, SLC25A5, IL1B, CAMK2DMore
Guaiacolhsa05133Pertussis4.20E-021P0C0L4C4AMore
Guaiacolhsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Guaiacolhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Guaiacolhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Guaiacolhsa05162Measles4.02E-023P11142, P01584, Q9NP90HSPA8, IL1B, RAB9BMore
Guaiacolhsa05171Coronavirus disease - COVID-199.72E-037P01584, P62753, P25398, P36578, P32969, P18077, P62829IL1B, RPS6, RPS12, RPL4, RPL9, RPL35A, RPL23More
Guaiacolhsa05202Transcriptional misregulation in cancer1.45E-0212Q15532, P41732, P14780, P27930, P14923, Q16548, Q13077, O15550, P35226, P05164, P08246, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, TRAF1, UTX, BMI1, MPO, ELA2, GADD45AMore
Guaiacolhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Guaiacolhsa05415Diabetic cardiomyopathy2.87E-024P05141, O15239, P13073, Q13557SLC25A5, NDUFA1, COX4I1, CAMK2DMore

Community members of Guaiacol (SDC: 3.14)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P02768ALBAlbuminReported10.28480.91110.08572.0502
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)