PharmaCoNets

PharmaCoNets of Griseofulvin (S_PCN: 16.78 )

Griseofulvin regulated-network (S_DN: 8.74)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Griseofulvin

hsa00010

Glycolysis / Gluconeogenesis

1.18E-02

P60174, P06744

TPI1, GPI

Griseofulvin

hsa00053

Ascorbate and aldarate metabolism

1.80E-02

P51648, Q9UEF7

ALDH3A2, KL

Griseofulvin

hsa00310

Lysine degradation

4.27E-02

Q96KQ7, P51648

EHMT2, ALDH3A2

Griseofulvin

hsa00515

Mannose type O-glycan biosynthesis

4.57E-02

O75072

FCMD

Griseofulvin

hsa00561

Glycerolipid metabolism

4.36E-03

O14494, P51648, P23743

PLPP1, ALDH3A2, DGKA

Griseofulvin

hsa00600

Sphingolipid metabolism

4.77E-02

Q9BX95, O14494, P06280

SGPP1, PLPP1, GLA

Griseofulvin

hsa00630

Glyoxylate and dicarboxylate metabolism

2.42E-02

P40925, P15104

MDH1, GLUL

Griseofulvin

hsa00983

Drug metabolism - other enzymes

4.77E-02

P04183, P32320, P05164

TK1, CDA, MPO

Griseofulvin

hsa01200

Carbon metabolism

1.99E-02

P06744, P60174

GPI, TPI1

Griseofulvin

hsa01521

EGFR tyrosine kinase inhibitor resistance

2.90E-02

P17252, P10415, Q9NRA1

PRKCA, BCL2, PDGFC

Griseofulvin

hsa01524

Platinum drug resistance

4.02E-02

Q13315, P10415, Q13489, P43246

ATM, BCL2, BIRC3, MSH2

Griseofulvin

hsa03013

RNA transport

2.82E-04

P52298, O14893, P61326, Q7Z3B4, P35658, Q99567, Q96D46, Q14152, O75822, P78345, Q9BZI7, Q9Y6A5, Q06787, P51114

NCBP2, GEMIN2, MAGOH, NUP54, NUP214, NUP88, NMD3, EIF3A, EIF3J, RPP38, UPF3B, TACC3, FMR1, FXR1

Griseofulvin

hsa03040

Spliceosome

1.45E-04

Q14562, O43143, O60508, P26368, P52298, Q13595, Q07955, Q01130, P84103, Q13243, P11142

DHX8, DHX15, CDC40, U2AF2, NCBP2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8

Griseofulvin

hsa04020

Calcium signaling pathway

2.09E-02

Q16566, P17252, P25116, P0DP23, Q9NRA1

CAMK4, PRKCA, F2R, CALM1, PDGFC

Griseofulvin

hsa04064

NF-kappa B signaling pathway

3.04E-03

P10415, Q13489, P25963, P51617, Q13546, Q9UDY8, Q13315, O75293

BCL2, BIRC3, NFKBIA, IRAK1, RIPK1, MALT1, ATM, GADD45B

Griseofulvin

hsa04071

Sphingolipid signaling pathway

2.95E-03

P17252, P21453, Q13362, Q9BX95, P10415, P01042

PRKCA, S1PR1, PPP2R5C, SGPP1, BCL2, KNG1

Griseofulvin

hsa04072

Phospholipase D signaling pathway

1.06E-02

P25116, P17252, O14494, P23743, Q9NRA1

F2R, PRKCA, PLPP1, DGKA, PDGFC

Griseofulvin

hsa04141

Protein processing in endoplasmic reticulum

2.77E-02

P27824, P30101, P60604, P11142, P08238

CANX, PDIA3, UBE2G2, HSPA8, HSP90AB1

Griseofulvin

hsa04145

Phagosome

3.68E-05

Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443, P27824

NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, CANX

Griseofulvin

hsa04213

Longevity regulating pathway - multiple species

2.85E-02

Q9Y4H2, Q13547

IRS2, HDAC1

Griseofulvin

hsa04217

Necroptosis

3.69E-05

P01568, Q13489, Q13546, P42224, P08238, Q6FI13, P10415, O43633

IFNA21, BIRC3, RIPK1, STAT1, HSP90AB1, H2AC18; H2AC19, BCL2, CHMP2A

Griseofulvin

hsa04371

Apelin signaling pathway

1.12E-03

P62873, P63218, P50151, Q13370, Q14344, Q13485, P84022, Q16566, P0DP23

GNB1, GNG5, GNG10, PDE3B, GNA13, SMAD4, SMAD3, CAMK4, CALM1

Griseofulvin

hsa04520

Adherens junction

8.77E-03

Q13485, P84022, O95863, Q15223

SMAD4, SMAD3, SNAI1, PVRL1

Griseofulvin

hsa04540

Gap junction

5.44E-03

P17252, Q13509, P68371, Q9NRA1

PRKCA, TUBB3, TUBB2C, PDGFC

Griseofulvin

hsa04613

Neutrophil extracellular trap formation

1.23E-03

P11215, Q13547, P58876, Q16778, O60814

ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12

Griseofulvin

hsa04620

Toll-like receptor signaling pathway

7.24E-03

P51617, Q13546, P01568, P42224, P25963

IRAK1, RIPK1, IFNA21, STAT1, NFKBIA

Griseofulvin

hsa04621

NOD-like receptor signaling pathway

4.54E-02

P08238, P42224, P01568, P25963, Q13489, P10415, Q13546

HSP90AB1, STAT1, IFNA21, NFKBIA, BIRC3, BCL2, RIPK1

Griseofulvin

hsa04623

Cytosolic DNA-sensing pathway

4.52E-05

P01568, Q13546, P25963

IFNA21, RIPK1, NFKBIA

Griseofulvin

hsa04659

Th17 cell differentiation

1.64E-02

P19174, P84022, Q13485, P08238, P07766

PLCG1, SMAD3, SMAD4, HSP90AB1, CD3E

Griseofulvin

hsa04664

Fc epsilon RI signaling pathway

2.35E-02

P07948, P19174, P09917

LYN, PLCG1, ALOX5

Griseofulvin

hsa04666

Fc gamma R-mediated phagocytosis

2.81E-02

P23528, O14494, P14598, P17252

CFL1, PLPP1, NCF1, PRKCA

Griseofulvin

hsa04710

Circadian rhythm

1.79E-02

O15516

CLOCK

Griseofulvin

hsa04720

Long-term potentiation

2.05E-02

P17252, Q16566, P0DP23

PRKCA, CAMK4, CALM1

Griseofulvin

hsa04724

Glutamatergic synapse

4.43E-02

P63218, P50151, P15104

GNG5, GNG10, GLUL

Griseofulvin

hsa04725

Cholinergic synapse

8.04E-03

P17252, P62873, Q16566, P10415

PRKCA, GNB1, CAMK4, BCL2

Griseofulvin

hsa04727

GABAergic synapse

4.43E-02

P63218, P50151, P15104

GNG5, GNG10, GLUL

Griseofulvin

hsa04744

Phototransduction

8.61E-05

P62873, P0DP23

GNB1, CALM1

Griseofulvin

hsa04915

Estrogen signaling pathway

2.99E-02

P19012

KRT15

Griseofulvin

hsa04916

Melanogenesis

2.90E-02

P0DP23, Q9UJU2, P17252

CALM1, LEF1, PRKCA

Griseofulvin

hsa04925

Aldosterone synthesis and secretion

3.91E-02

P0DP23, P17252, Q16566

CALM1, PRKCA, CAMK4

Griseofulvin

hsa04961

Endocrine and other factor-regulated calcium reabsorption

6.76E-04

P20020, Q9UEF7, P17252

ATP2B1, KL, PRKCA

Griseofulvin

hsa04972

Pancreatic secretion

2.68E-02

Q14643, P20020, P17252

ITPR1, ATP2B1, PRKCA

Griseofulvin

hsa04975

Fat digestion and absorption

4.57E-02

O14494

PLPP1

Griseofulvin

hsa05032

Morphine addiction

4.43E-02

P63218, P50151, P43250

GNG5, GNG10, GRK6

Griseofulvin

hsa05034

Alcoholism

2.10E-03

Q13547, P58876, Q16778, O60814

HDAC1, H2BC5, HIST2H2BE, H2BC12

Griseofulvin

hsa05132

Salmonella infection

3.59E-07

P51617, P25963, P08238, Q9UJU2, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, Q13509, P68371

IRAK1, NFKBIA, HSP90AB1, LEF1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, TUBB3, TUBB2C

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	0.741
Q13509	TUBB3	Tubulin beta-3 chain	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.757
Q13509	TUBB3	Tubulin beta-3 chain	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.714
P68371	TUBB2C	Tubulin beta-4B chain	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.741
Q13509	TUBB3	Tubulin beta-3 chain	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.789
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q9UJU2	LEF1	Lymphoid enhancer-binding factor 1	0.825
P68371	TUBB2C	Tubulin beta-4B chain	Q9UJU2	LEF1	Lymphoid enhancer-binding factor 1	-0.714
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	-0.769
P68371	TUBB2C	Tubulin beta-4B chain	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	0.748
Q13509	TUBB3	Tubulin beta-3 chain	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	0.735
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	0.794
P68371	TUBB2C	Tubulin beta-4B chain	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.892
Q13509	TUBB3	Tubulin beta-3 chain	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.716
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P10415	BCL2	Apoptosis regulator Bcl-2	0.94
P68371	TUBB2C	Tubulin beta-4B chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.766
Q13509	TUBB3	Tubulin beta-3 chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.809
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	O75369	FLNB	Filamin-B	-0.746
Q13509	TUBB3	Tubulin beta-3 chain	O75369	FLNB	Filamin-B	0.914
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	O60603	TLR2	Toll-like receptor 2	-0.862
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q9BQS8	FYCO1	FYVE and coiled-coil domain-containing protein 1	0.924
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13561	DCTN2	Dynactin subunit 2	-0.809
P68371	TUBB2C	Tubulin beta-4B chain	Q13561	DCTN2	Dynactin subunit 2	0.715
Q13509	TUBB3	Tubulin beta-3 chain	Q13561	DCTN2	Dynactin subunit 2	0.74
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13509	TUBB3	Tubulin beta-3 chain	-0.846
P68371	TUBB2C	Tubulin beta-4B chain	Q13509	TUBB3	Tubulin beta-3 chain	0.78
Q13509	TUBB3	Tubulin beta-3 chain	Q13509	TUBB3	Tubulin beta-3 chain	1
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P68371	TUBB2C	Tubulin beta-4B chain	-0.783
P68371	TUBB2C	Tubulin beta-4B chain	P68371	TUBB2C	Tubulin beta-4B chain	1
Q13509	TUBB3	Tubulin beta-3 chain	P68371	TUBB2C	Tubulin beta-4B chain	0.78

Griseofulvin

hsa05140

Leishmaniasis

4.05E-03

P14598, P42224, P25963, P29350, P51617, Q15080

NCF1, STAT1, NFKBIA, PTPN6, IRAK1, NCF4

Griseofulvin

hsa05145

Toxoplasmosis

1.95E-02

P51617, P25963, P10415, Q13489, P42224, P11142

IRAK1, NFKBIA, BCL2, BIRC3, STAT1, HSPA8

Griseofulvin

hsa05150

Staphylococcus aureus infection

2.98E-04

P19012, Q14532, P16109, P59665, P59666

KRT15, KRT32, SELP, DEFA1; DEFA1B, DEFA3

Griseofulvin

hsa05152

Tuberculosis

2.49E-05

Q13488, P0DP23, P42224, P48382, P25208, O60603, P10415, P01568, Q9UDY8, P51617

TCIRG1, CALM1, STAT1, RFX5, NFYB, TLR2, BCL2, IFNA21, MALT1, IRAK1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13488	TCIRG1	V-type proton ATPase 116 kDa subunit a 3	-0.716
P68371	TUBB2C	Tubulin beta-4B chain	Q13488	TCIRG1	V-type proton ATPase 116 kDa subunit a 3	0.729
P68371	TUBB2C	Tubulin beta-4B chain	P0DP23	CALM1	Calmodulin-1	0.742
Q13509	TUBB3	Tubulin beta-3 chain	P0DP23	CALM1	Calmodulin-1	0.892
Q13509	TUBB3	Tubulin beta-3 chain	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.733
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P48382	RFX5	DNA-binding protein RFX5	0.797
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P25208	NFYB	Nuclear transcription factor Y subunit beta	0.742
Q13509	TUBB3	Tubulin beta-3 chain	P25208	NFYB	Nuclear transcription factor Y subunit beta	-0.709
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	O60603	TLR2	Toll-like receptor 2	-0.862
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P10415	BCL2	Apoptosis regulator Bcl-2	0.94
P68371	TUBB2C	Tubulin beta-4B chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.766
Q13509	TUBB3	Tubulin beta-3 chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.809
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P01568	IFNA21	Interferon alpha-21	0.716
P68371	TUBB2C	Tubulin beta-4B chain	P01568	IFNA21	Interferon alpha-21	-0.783
Q13509	TUBB3	Tubulin beta-3 chain	P01568	IFNA21	Interferon alpha-21	-0.781
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	1
P68371	TUBB2C	Tubulin beta-4B chain	Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	-0.783
Q13509	TUBB3	Tubulin beta-3 chain	Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	-0.846
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	0.741
Q13509	TUBB3	Tubulin beta-3 chain	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.757

Griseofulvin

hsa05162

Measles

4.50E-03

P51617, P01568, P25963, P42224, P14784, P10747, P11142, P10415

IRAK1, IFNA21, NFKBIA, STAT1, IL2RB, CD28, HSPA8, BCL2

Griseofulvin

hsa05166

Human T-cell leukemia virus 1 infection

1.77E-02

P27824, P30279, P21796, P84022, Q13485, P07766, Q92830, P06746

CANX, CCND2, VDAC1, SMAD3, SMAD4, CD3E, KAT2A, POLB

Griseofulvin

hsa05168

Herpes simplex virus 1 infection

5.65E-04

P25963, P01568, P42224, Q07955, Q01130, Q13243, Q13489, P51617, Q13398, Q9NR11, P17097, P17038, Q03923, P10415

NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, IRAK1, ZNF211, ZNF302, ZNF7, ZNF43, ZNF85, BCL2

Griseofulvin

hsa05170

Human immunodeficiency virus 1 infection

4.91E-06

P62873, P0DP23, P17252, Q13546, Q14643, P01568, P51617, P25963, O60603, Q13315, P23528, P10415, Q9Y6Q5

GNB1, CALM1, PRKCA, RIPK1, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CFL1, BCL2, AP1M2

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	-0.701
P68371	TUBB2C	Tubulin beta-4B chain	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.82
Q13509	TUBB3	Tubulin beta-3 chain	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.816
P68371	TUBB2C	Tubulin beta-4B chain	P0DP23	CALM1	Calmodulin-1	0.742
Q13509	TUBB3	Tubulin beta-3 chain	P0DP23	CALM1	Calmodulin-1	0.892
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P17252	PRKCA	Protein kinase C alpha type	0.769
P68371	TUBB2C	Tubulin beta-4B chain	P17252	PRKCA	Protein kinase C alpha type	-0.842
Q13509	TUBB3	Tubulin beta-3 chain	P17252	PRKCA	Protein kinase C alpha type	-0.756
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	-0.769
P68371	TUBB2C	Tubulin beta-4B chain	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	0.748
Q13509	TUBB3	Tubulin beta-3 chain	Q13546	RIPK1	Receptor-interacting serine/threonine-protein kinase 1	0.735
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q14643	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1	0.823
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P01568	IFNA21	Interferon alpha-21	0.716
P68371	TUBB2C	Tubulin beta-4B chain	P01568	IFNA21	Interferon alpha-21	-0.783
Q13509	TUBB3	Tubulin beta-3 chain	P01568	IFNA21	Interferon alpha-21	-0.781
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	0.741
Q13509	TUBB3	Tubulin beta-3 chain	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.757
Q13509	TUBB3	Tubulin beta-3 chain	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.714
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	O60603	TLR2	Toll-like receptor 2	-0.862
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q13315	ATM	Serine-protein kinase ATM	0.758
P68371	TUBB2C	Tubulin beta-4B chain	Q13315	ATM	Serine-protein kinase ATM	-0.772
Q13509	TUBB3	Tubulin beta-3 chain	P23528	CFL1	Cofilin-1	-0.726
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	P10415	BCL2	Apoptosis regulator Bcl-2	0.94
P68371	TUBB2C	Tubulin beta-4B chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.766
Q13509	TUBB3	Tubulin beta-3 chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.809
Q9UDY8	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	-0.946
P68371	TUBB2C	Tubulin beta-4B chain	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	0.753
Q13509	TUBB3	Tubulin beta-3 chain	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	0.886

Griseofulvin

hsa05200

Pathways in cancer

2.19E-05

P04628, Q13751, P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, P14923, P30279, P10415, Q13489, Q12778, P25116, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784, P01042

WNT1, LAMB3, HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, JUP, CCND2, BCL2, BIRC3, FOXO1, F2R, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RB, KNG1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q13509	TUBB3	Tubulin beta-3 chain	P04628	WNT1	Proto-oncogene Wnt-1	-0.709
Q71U36	TUBA1A	Tubulin alpha-1A chain	Q13751	LAMB3	Laminin subunit beta-3	0.748
P68371	TUBB2C	Tubulin beta-4B chain	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.741
Q13509	TUBB3	Tubulin beta-3 chain	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.789
Q71U36	TUBA1A	Tubulin alpha-1A chain	P08238	HSP90AB1	Heat shock protein HSP 90-beta	-0.866
Q13509	TUBB3	Tubulin beta-3 chain	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.733
Q13509	TUBB3	Tubulin beta-3 chain	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.714
Q71U36	TUBA1A	Tubulin alpha-1A chain	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	-0.7
P68371	TUBB2C	Tubulin beta-4B chain	Q9UJU2	LEF1	Lymphoid enhancer-binding factor 1	-0.714
P68371	TUBB2C	Tubulin beta-4B chain	P17252	PRKCA	Protein kinase C alpha type	-0.842
Q13509	TUBB3	Tubulin beta-3 chain	P17252	PRKCA	Protein kinase C alpha type	-0.756
P68371	TUBB2C	Tubulin beta-4B chain	P43246	MSH2	DNA mismatch repair protein Msh2	0.709
Q13509	TUBB3	Tubulin beta-3 chain	P43246	MSH2	DNA mismatch repair protein Msh2	0.872
Q71U36	TUBA1A	Tubulin alpha-1A chain	P84022	SMAD3	Mothers against decapentaplegic homolog 3	0.819
Q71U36	TUBA1A	Tubulin alpha-1A chain	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	-0.777
Q71U36	TUBA1A	Tubulin alpha-1A chain	P20585	MSH3	DNA mismatch repair protein Msh3	-0.745
P68371	TUBB2C	Tubulin beta-4B chain	P14923	JUP	Junction plakoglobin	-0.781
Q13509	TUBB3	Tubulin beta-3 chain	P14923	JUP	Junction plakoglobin	-0.937
Q71U36	TUBA1A	Tubulin alpha-1A chain	P30279	CCND2	G1/S-specific cyclin-D2	-0.721
P68371	TUBB2C	Tubulin beta-4B chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.766
Q13509	TUBB3	Tubulin beta-3 chain	P10415	BCL2	Apoptosis regulator Bcl-2	-0.809
P68371	TUBB2C	Tubulin beta-4B chain	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.892
Q13509	TUBB3	Tubulin beta-3 chain	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.716
P68371	TUBB2C	Tubulin beta-4B chain	Q12778	FOXO1	Forkhead box protein O1	-0.895
P68371	TUBB2C	Tubulin beta-4B chain	P25116	F2R	Proteinase-activated receptor 1	-0.799
P68371	TUBB2C	Tubulin beta-4B chain	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.82
Q13509	TUBB3	Tubulin beta-3 chain	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.816
Q71U36	TUBA1A	Tubulin alpha-1A chain	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	0.818
Q71U36	TUBA1A	Tubulin alpha-1A chain	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	0.827
Q71U36	TUBA1A	Tubulin alpha-1A chain	Q14344	GNA13	Guanine nucleotide-binding protein subunit alpha-13	0.879
Q13509	TUBB3	Tubulin beta-3 chain	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.826
P68371	TUBB2C	Tubulin beta-4B chain	P0DP23	CALM1	Calmodulin-1	0.742
Q13509	TUBB3	Tubulin beta-3 chain	P0DP23	CALM1	Calmodulin-1	0.892
P68371	TUBB2C	Tubulin beta-4B chain	P01568	IFNA21	Interferon alpha-21	-0.783
Q13509	TUBB3	Tubulin beta-3 chain	P01568	IFNA21	Interferon alpha-21	-0.781
Q13509	TUBB3	Tubulin beta-3 chain	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.709
P68371	TUBB2C	Tubulin beta-4B chain	P01042	KNG1	Kininogen-1	-0.7