PharmaCoNets of Glycopyrronium (SPCN: 19.72 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Glycopyrroniumhsa00630Glyoxylate and dicarboxylate metabolism2.27E-052P40925, P15104MDH1, GLULMore
Glycopyrroniumhsa03040Spliceosome8.73E-048Q14562, O43143, O60508, P08579, Q07955, Q01130, Q13243, O43447DHX8, DHX15, CDC40, SNRPB2, SFRS1, SFRS2, SFRS5, PPIHMore
Glycopyrroniumhsa04024cAMP signaling pathway4.38E-024P42338, P0DP23, Q13370, Q13009PIK3CB, CALM1, PDE3B, TIAM1More
Glycopyrroniumhsa04070Phosphatidylinositol signaling system4.86E-023P0DP23, P42338, P27987CALM1, PIK3CB, ITPKBMore
Glycopyrroniumhsa04114Oocyte meiosis1.33E-024P51812, Q02750, P16298, Q17RY0RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Glycopyrroniumhsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Glycopyrroniumhsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Glycopyrroniumhsa04360Axon guidance1.71E-024P20827, O95631, P42338, P23528EFNA1, NTN1, PIK3CB, CFL1More
Glycopyrroniumhsa04370VEGF signaling pathway2.68E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Glycopyrroniumhsa04613Neutrophil extracellular trap formation1.23E-035P11215, Q13547, P58876, Q16778, O60814ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12More
Glycopyrroniumhsa04650Natural killer cell mediated cytotoxicity2.94E-023P16298, P50591, Q02750PPP3CB, TNFSF10, MAP2K1More
Glycopyrroniumhsa04659Th17 cell differentiation4.38E-024P42224, P14784, P40189, P08238STAT1, IL2RB, IL6ST, HSP90AB1More
Glycopyrroniumhsa04662B cell receptor signaling pathway1.49E-035P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Glycopyrroniumhsa04664Fc epsilon RI signaling pathway2.32E-023P42338, P07948, P09917PIK3CB, LYN, ALOX5More
Glycopyrroniumhsa04666Fc gamma R-mediated phagocytosis3.08E-023P42338, P23528, P14598PIK3CB, CFL1, NCF1More
Glycopyrroniumhsa04720Long-term potentiation1.38E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Glycopyrroniumhsa04724Glutamatergic synapse5.94E-034O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Glycopyrroniumhsa04725Cholinergic synapse4.10E-023P63218, P50151, P42338GNG5, GNG10, PIK3CBMore
Glycopyrroniumhsa04727GABAergic synapse1.63E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Glycopyrroniumhsa04914Progesterone-mediated oocyte maturation2.97E-036Q17RY0, P42338, Q13370, P08238, P51812, Q02750CPEB4, PIK3CB, PDE3B, HSP90AB1, RPS6KA3, MAP2K1More
Glycopyrroniumhsa04924Renin secretion3.77E-022Q13370, P0DP23PDE3B, CALM1More
Glycopyrroniumhsa04926Relaxin signaling pathway5.70E-035P42338, P63218, P50151, P49767, P49407PIK3CB, GNG5, GNG10, VEGFC, ARRB1More
Glycopyrroniumhsa04929GnRH secretion4.62E-022P42338, P49407PIK3CB, ARRB1More
Glycopyrroniumhsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Glycopyrroniumhsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Glycopyrroniumhsa05168Herpes simplex virus 1 infection1.15E-028P42224, Q07955, Q01130, Q13243, P42338, Q13398, Q03923, Q9UDV6STAT1, SFRS1, SFRS2, SFRS5, PIK3CB, ZNF211, ZNF85, ZNF212More
Glycopyrroniumhsa05169Epstein-Barr virus infection3.72E-026Q13547, P42338, P07948, Q13761, O75293, P07766HDAC1, PIK3CB, LYN, RUNX3, GADD45B, CD3EMore
Glycopyrroniumhsa05170Human immunodeficiency virus 1 infection6.02E-035Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Glycopyrroniumhsa05200Pathways in cancer3.92E-029P42338, P08238, P42224, P43246, P14923, O75293, P0DP23, P14784, P40189PIK3CB, HSP90AB1, STAT1, MSH2, JUP, GADD45B, CALM1, IL2RB, IL6STMore
Glycopyrroniumhsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Glycopyrroniumhsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Glycopyrroniumhsa05212Pancreatic cancer1.72E-023P42338, P42224, O75293PIK3CB, STAT1, GADD45BMore
Glycopyrroniumhsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Glycopyrroniumhsa05214Glioma1.72E-023P0DP23, P42338, O75293CALM1, PIK3CB, GADD45BMore
Glycopyrroniumhsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Glycopyrroniumhsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Glycopyrroniumhsa05418Fluid shear stress and atherosclerosis3.73E-024P42338, P14598, P0DP23, P08238PIK3CB, NCF1, CALM1, HSP90AB1More

Community members of Glycopyrronium (SDC: 3.85)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)