PharmaCoNets of Glutathione-disulfide (SPCN: 10.24 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Glutathione-disulfidehsa00040Pentose and glucuronate interconversions2.33E-042P15121, P14550AKR1B1, AKR1A1More
Glutathione-disulfidehsa00120Primary bile acid biosynthesis3.72E-022P22680, P22307CYP7A1, SCP2More
Glutathione-disulfidehsa00480Glutathione metabolism2.31E-021P22352GPX3More
Glutathione-disulfidehsa00510N-Glycan biosynthesis3.01E-021O94777DPM2More
Glutathione-disulfidehsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Glutathione-disulfidehsa00561Glycerolipid metabolism2.62E-022P15121, P14550AKR1B1, AKR1A1More
Glutathione-disulfidehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis1.51E-021O94777DPM2More
Glutathione-disulfidehsa00590Arachidonic acid metabolism6.63E-031P22352GPX3More
Glutathione-disulfidehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Glutathione-disulfidehsa00630Glyoxylate and dicarboxylate metabolism6.94E-032P40925, P15104MDH1, GLULMore
Glutathione-disulfidehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Glutathione-disulfidehsa00980Metabolism of xenobiotics by cytochrome P4504.00E-021P09211GSTP1More
Glutathione-disulfidehsa00983Drug metabolism - other enzymes1.63E-022P20839, Q16772IMPDH1, GSTA3More
Glutathione-disulfidehsa01100Metabolic pathways1.57E-0314P35790, Q16772, P36969, P30041, P20839, O94777, P15121, O95861, P14550, Q9UHK6, P04406, Q86VZ5, Q06055, Q9NVH6CHKA, GSTA3, GPX4, PRDX6, IMPDH1, DPM2, AKR1B1, BPNT1, AKR1A1, AMACR, GAPDH, SGMS1, ATP5G2, TMLHEMore
Glutathione-disulfidehsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Glutathione-disulfidehsa01524Platinum drug resistance4.67E-024Q13489, P98170, P78417, P43246BIRC3, BIRC4, GSTO1, MSH2More
Glutathione-disulfidehsa03010Ribosome2.25E-045P40429, Q07020, P27635, P05386, P62249RPL13A, RPL18, RPL10, RPLP1, RPS16More
Glutathione-disulfidehsa03040Spliceosome4.87E-037O43143, P08579, P26368, Q13595, Q07955, P84103, Q13243DHX15, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS3, SFRS5More
Glutathione-disulfidehsa04062Chemokine signaling pathway3.81E-026P07948, P62873, P63218, P50151, P43250, Q13009LYN, GNB1, GNG5, GNG10, GRK6, TIAM1More
Glutathione-disulfidehsa04217Necroptosis1.37E-026P01568, Q13489, P98170, P08238, P15104, P21796IFNA21, BIRC3, BIRC4, HSP90AB1, GLUL, VDAC1More
Glutathione-disulfidehsa04371Apelin signaling pathway3.23E-047P62873, P63218, P50151, Q13485, P84022, Q16566, P0DP23GNB1, GNG5, GNG10, SMAD4, SMAD3, CAMK4, CALM1More
Glutathione-disulfidehsa04390Hippo signaling pathway4.35E-022P63261, O15105ACTG1, SMAD7More
Glutathione-disulfidehsa04530Tight junction4.35E-022P63261, Q92974ACTG1, ARHGEF2More
Glutathione-disulfidehsa04713Circadian entrainment1.78E-035O15399, P0DP23, P62873, P63218, P50151GRIN2D, CALM1, GNB1, GNG5, GNG10More
Glutathione-disulfidehsa04720Long-term potentiation2.33E-023Q16566, P0DP23, O15399CAMK4, CALM1, GRIN2DMore
Glutathione-disulfidehsa04724Glutamatergic synapse1.11E-035O15399, P62873, P63218, P50151, P15104GRIN2D, GNB1, GNG5, GNG10, GLULMore
Glutathione-disulfidehsa04725Cholinergic synapse9.51E-034P62873, P63218, P50151, Q16566GNB1, GNG5, GNG10, CAMK4More
Glutathione-disulfidehsa04726Serotonergic synapse2.38E-024P62873, P63218, P50151, P09917GNB1, GNG5, GNG10, ALOX5More
Glutathione-disulfidehsa04727GABAergic synapse2.45E-034P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Glutathione-disulfidehsa04744Phototransduction6.94E-032P62873, P0DP23GNB1, CALM1More
Glutathione-disulfidehsa04918Thyroid hormone synthesis3.62E-021P22352GPX3More
Glutathione-disulfidehsa05010Alzheimer disease2.05E-033Q06055, P04406, P62195ATP5G2, GAPDH, PSMC5More
Glutathione-disulfidehsa05012Parkinson disease2.21E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05014Amyotrophic lateral sclerosis3.35E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05016Huntington disease2.48E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05020Prion disease3.20E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05022Pathways of neurodegeneration - multiple diseases4.69E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05032Morphine addiction1.34E-024P62873, P63218, P50151, P43250GNB1, GNG5, GNG10, GRK6More
Glutathione-disulfidehsa05034Alcoholism3.87E-037O15399, Q16566, P0DP23, P62873, P63218, P50151, Q93079GRIN2D, CAMK4, CALM1, GNB1, GNG5, GNG10, H2BC9More
Glutathione-disulfidehsa05163Human cytomegalovirus infection2.00E-026P62873, P63218, P50151, P0DP23, P30101, P01568GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21More
Glutathione-disulfidehsa05167Kaposi sarcoma-associated herpesvirus infection2.00E-026P01568, P62873, P63218, P50151, P07948, P0DP23IFNA21, GNB1, GNG5, GNG10, LYN, CALM1More
Glutathione-disulfidehsa05168Herpes simplex virus 1 infection4.43E-028P01568, Q07955, P84103, Q13243, Q13489, P30101, Q13398, Q9NZL3IFNA21, SFRS1, SFRS3, SFRS5, BIRC3, PDIA3, ZNF211, ZNF224More
Glutathione-disulfidehsa05170Human immunodeficiency virus 1 infection1.83E-027P62873, P63218, P50151, P0DP23, P30101, P01568, P23528GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21, CFL1More
Glutathione-disulfidehsa05171Coronavirus disease - COVID-193.87E-045P62249, P40429, P27635, Q07020, P05386RPS16, RPL13A, RPL10, RPL18, RPLP1More
Glutathione-disulfidehsa05200Pathways in cancer3.99E-0415Q13751, P08238, P43246, P84022, Q13485, Q13489, P98170, P62873, P63218, P50151, P78417, O75293, P0DP23, P01568, P01042LAMB3, HSP90AB1, MSH2, SMAD3, SMAD4, BIRC3, BIRC4, GNB1, GNG5, GNG10, GSTO1, GADD45B, CALM1, IFNA21, KNG1More
Glutathione-disulfidehsa05204Chemical carcinogenesis4.00E-021P09211GSTP1More
Glutathione-disulfidehsa05210Colorectal cancer4.67E-024P84022, Q13485, P43246, O75293SMAD3, SMAD4, MSH2, GADD45BMore
Glutathione-disulfidehsa05212Pancreatic cancer3.28E-023P84022, Q13485, O75293SMAD3, SMAD4, GADD45BMore
Glutathione-disulfidehsa05214Glioma3.28E-023P0DP23, Q16566, O75293CALM1, CAMK4, GADD45BMore
Glutathione-disulfidehsa05222Small cell lung cancer3.80E-024Q13751, Q13489, P98170, O75293LAMB3, BIRC3, BIRC4, GADD45BMore
Glutathione-disulfidehsa05415Diabetic cardiomyopathy1.09E-022Q06055, P04406ATP5G2, GAPDHMore

Community members of Glutathione-disulfide (SDC: 1.63)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)