PharmaCoNets of Glutathione (SPCN: 40.13 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Glutathione-disulfidehsa00040Pentose and glucuronate interconversions2.33E-042P15121, P14550AKR1B1, AKR1A1More
Glutathione-disulfidehsa00120Primary bile acid biosynthesis3.72E-022P22680, P22307CYP7A1, SCP2More
Glutathione-disulfidehsa00480Glutathione metabolism2.31E-021P22352GPX3More
Glutathione-disulfidehsa00510N-Glycan biosynthesis3.01E-021O94777DPM2More
Glutathione-disulfidehsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Glutathione-disulfidehsa00561Glycerolipid metabolism2.62E-022P15121, P14550AKR1B1, AKR1A1More
Glutathione-disulfidehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis1.51E-021O94777DPM2More
Glutathione-disulfidehsa00590Arachidonic acid metabolism6.63E-031P22352GPX3More
Glutathione-disulfidehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Glutathione-disulfidehsa00630Glyoxylate and dicarboxylate metabolism6.94E-032P40925, P15104MDH1, GLULMore
Glutathione-disulfidehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Glutathione-disulfidehsa00980Metabolism of xenobiotics by cytochrome P4504.00E-021P09211GSTP1More
Glutathione-disulfidehsa00983Drug metabolism - other enzymes1.63E-022P20839, Q16772IMPDH1, GSTA3More
Glutathione-disulfidehsa01100Metabolic pathways1.57E-0314P35790, Q16772, P36969, P30041, P20839, O94777, P15121, O95861, P14550, Q9UHK6, P04406, Q86VZ5, Q06055, Q9NVH6CHKA, GSTA3, GPX4, PRDX6, IMPDH1, DPM2, AKR1B1, BPNT1, AKR1A1, AMACR, GAPDH, SGMS1, ATP5G2, TMLHEMore
Glutathione-disulfidehsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Glutathione-disulfidehsa01524Platinum drug resistance4.67E-024Q13489, P98170, P78417, P43246BIRC3, BIRC4, GSTO1, MSH2More
Glutathione-disulfidehsa03010Ribosome2.25E-045P40429, Q07020, P27635, P05386, P62249RPL13A, RPL18, RPL10, RPLP1, RPS16More
Glutathione-disulfidehsa03040Spliceosome4.87E-037O43143, P08579, P26368, Q13595, Q07955, P84103, Q13243DHX15, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS3, SFRS5More
Glutathione-disulfidehsa04062Chemokine signaling pathway3.81E-026P07948, P62873, P63218, P50151, P43250, Q13009LYN, GNB1, GNG5, GNG10, GRK6, TIAM1More
Glutathione-disulfidehsa04217Necroptosis1.37E-026P01568, Q13489, P98170, P08238, P15104, P21796IFNA21, BIRC3, BIRC4, HSP90AB1, GLUL, VDAC1More
Glutathione-disulfidehsa04371Apelin signaling pathway3.23E-047P62873, P63218, P50151, Q13485, P84022, Q16566, P0DP23GNB1, GNG5, GNG10, SMAD4, SMAD3, CAMK4, CALM1More
Glutathione-disulfidehsa04390Hippo signaling pathway4.35E-022P63261, O15105ACTG1, SMAD7More
Glutathione-disulfidehsa04530Tight junction4.35E-022P63261, Q92974ACTG1, ARHGEF2More
Glutathione-disulfidehsa04713Circadian entrainment1.78E-035O15399, P0DP23, P62873, P63218, P50151GRIN2D, CALM1, GNB1, GNG5, GNG10More
Glutathione-disulfidehsa04720Long-term potentiation2.33E-023Q16566, P0DP23, O15399CAMK4, CALM1, GRIN2DMore
Glutathione-disulfidehsa04724Glutamatergic synapse1.11E-035O15399, P62873, P63218, P50151, P15104GRIN2D, GNB1, GNG5, GNG10, GLULMore
Glutathione-disulfidehsa04725Cholinergic synapse9.51E-034P62873, P63218, P50151, Q16566GNB1, GNG5, GNG10, CAMK4More
Glutathione-disulfidehsa04726Serotonergic synapse2.38E-024P62873, P63218, P50151, P09917GNB1, GNG5, GNG10, ALOX5More
Glutathione-disulfidehsa04727GABAergic synapse2.45E-034P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Glutathione-disulfidehsa04744Phototransduction6.94E-032P62873, P0DP23GNB1, CALM1More
Glutathione-disulfidehsa04918Thyroid hormone synthesis3.62E-021P22352GPX3More
Glutathione-disulfidehsa05010Alzheimer disease2.05E-033Q06055, P04406, P62195ATP5G2, GAPDH, PSMC5More
Glutathione-disulfidehsa05012Parkinson disease2.21E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05014Amyotrophic lateral sclerosis3.35E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05016Huntington disease2.48E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05020Prion disease3.20E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05022Pathways of neurodegeneration - multiple diseases4.69E-022Q06055, P62195ATP5G2, PSMC5More
Glutathione-disulfidehsa05032Morphine addiction1.34E-024P62873, P63218, P50151, P43250GNB1, GNG5, GNG10, GRK6More
Glutathione-disulfidehsa05034Alcoholism3.87E-037O15399, Q16566, P0DP23, P62873, P63218, P50151, Q93079GRIN2D, CAMK4, CALM1, GNB1, GNG5, GNG10, H2BC9More
Glutathione-disulfidehsa05163Human cytomegalovirus infection2.00E-026P62873, P63218, P50151, P0DP23, P30101, P01568GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21More
Glutathione-disulfidehsa05167Kaposi sarcoma-associated herpesvirus infection2.00E-026P01568, P62873, P63218, P50151, P07948, P0DP23IFNA21, GNB1, GNG5, GNG10, LYN, CALM1More
Glutathione-disulfidehsa05168Herpes simplex virus 1 infection4.43E-028P01568, Q07955, P84103, Q13243, Q13489, P30101, Q13398, Q9NZL3IFNA21, SFRS1, SFRS3, SFRS5, BIRC3, PDIA3, ZNF211, ZNF224More
Glutathione-disulfidehsa05170Human immunodeficiency virus 1 infection1.83E-027P62873, P63218, P50151, P0DP23, P30101, P01568, P23528GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21, CFL1More
Glutathione-disulfidehsa05171Coronavirus disease - COVID-193.87E-045P62249, P40429, P27635, Q07020, P05386RPS16, RPL13A, RPL10, RPL18, RPLP1More
Glutathione-disulfidehsa05200Pathways in cancer3.99E-0415Q13751, P08238, P43246, P84022, Q13485, Q13489, P98170, P62873, P63218, P50151, P78417, O75293, P0DP23, P01568, P01042LAMB3, HSP90AB1, MSH2, SMAD3, SMAD4, BIRC3, BIRC4, GNB1, GNG5, GNG10, GSTO1, GADD45B, CALM1, IFNA21, KNG1More
Glutathione-disulfidehsa05204Chemical carcinogenesis4.00E-021P09211GSTP1More
Glutathione-disulfidehsa05210Colorectal cancer4.67E-024P84022, Q13485, P43246, O75293SMAD3, SMAD4, MSH2, GADD45BMore
Glutathione-disulfidehsa05212Pancreatic cancer3.28E-023P84022, Q13485, O75293SMAD3, SMAD4, GADD45BMore
Glutathione-disulfidehsa05214Glioma3.28E-023P0DP23, Q16566, O75293CALM1, CAMK4, GADD45BMore
Glutathione-disulfidehsa05222Small cell lung cancer3.80E-024Q13751, Q13489, P98170, O75293LAMB3, BIRC3, BIRC4, GADD45BMore
Glutathione-disulfidehsa05415Diabetic cardiomyopathy1.09E-022Q06055, P04406ATP5G2, GAPDHMore
Glutathionehsa00040Pentose and glucuronate interconversions2.33E-042P15121, P14550AKR1B1, AKR1A1More
Glutathionehsa00120Primary bile acid biosynthesis3.72E-022P22680, P22307CYP7A1, SCP2More
Glutathionehsa00230Purine metabolism4.88E-022P20839, Q16774IMPDH1, GUK1More
Glutathionehsa00480Glutathione metabolism2.32E-055Q9UJ14, P22352, Q16772, P09211, P30041GGTL3, GPX3, GSTA3, GSTP1, PRDX6More
Glutathionehsa00510N-Glycan biosynthesis3.01E-021O94777DPM2More
Glutathionehsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Glutathionehsa00561Glycerolipid metabolism4.48E-044Q8NEB5, P15121, P14550, Q86XP1PPAPDC1B, AKR1B1, AKR1A1, DGKHMore
Glutathionehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis1.51E-021O94777DPM2More
Glutathionehsa00590Arachidonic acid metabolism6.63E-031P22352GPX3More
Glutathionehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Glutathionehsa00620Pyruvate metabolism3.19E-022P40926, P14550MDH2, AKR1A1More
Glutathionehsa00630Glyoxylate and dicarboxylate metabolism6.94E-032P40925, P15104MDH1, GLULMore
Glutathionehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Glutathionehsa00970Aminoacyl-tRNA biosynthesis3.34E-021P14868DARSMore
Glutathionehsa00980Metabolism of xenobiotics by cytochrome P4503.60E-054Q16772, P78417, P09211, P11712GSTA3, GSTO1, GSTP1, CYP2C9More
Glutathionehsa00982Drug metabolism - cytochrome P4507.77E-044P11712, Q16772, P09211, P78417CYP2C9, GSTA3, GSTP1, GSTO1More
Glutathionehsa00983Drug metabolism - other enzymes5.54E-043P20839, Q16772, P09211IMPDH1, GSTA3, GSTP1More
Glutathionehsa01100Metabolic pathways4.72E-0519P35790, Q16772, P09211, Q9UJ14, P36969, P30041, P20839, P40926, O94777, Q7KZN9, P15121, O95861, P14550, Q9UHK6, P04406, Q86VZ5, Q9BQB6, Q06055, Q9NVH6CHKA, GSTA3, GSTP1, GGTL3, GPX4, PRDX6, IMPDH1, MDH2, DPM2, COX15, AKR1B1, BPNT1, AKR1A1, AMACR, GAPDH, SGMS1, VKORC1, ATP5G2, TMLHEMore
Glutathionehsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Glutathionehsa01524Platinum drug resistance4.38E-036Q13489, P98170, Q16772, P09211, P78417, P43246BIRC3, BIRC4, GSTA3, GSTP1, GSTO1, MSH2More
Glutathionehsa03010Ribosome2.25E-045P40429, Q07020, P27635, P05386, P62249RPL13A, RPL18, RPL10, RPLP1, RPS16More
Glutathionehsa03013RNA transport2.20E-026Q15287, Q9UBU9, P35658, P63279, P55884, P11940RNPS1, NXF1, NUP214, UBE2I, EIF3B, PABPC1More
Glutathionehsa03030DNA replication1.05E-034P33991, P49005, P33993, P15927MCM4, POLD2, MCM7, RPA2More
Glutathionehsa03040Spliceosome1.94E-048O43143, P08579, P26368, Q13595, Q07955, P84103, Q13243, P11142DHX15, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS3, SFRS5, HSPA8More
Glutathionehsa03440Homologous recombination2.95E-032O75771, Q06609RAD51D, RAD51More
Glutathionehsa04014Ras signaling pathway4.12E-025P20827, P49767, Q14644, P0DP23, P63218EFNA1, VEGFC, RASA3, CALM1, GNG5More
Glutathionehsa04020Calcium signaling pathway3.36E-036Q16566, P30679, O15399, P0DP23, P23634, P49767CAMK4, GNA15, GRIN2D, CALM1, ATP2B4, VEGFCMore
Glutathionehsa04062Chemokine signaling pathway3.81E-026P07948, P62873, P63218, P50151, P43250, Q13009LYN, GNB1, GNG5, GNG10, GRK6, TIAM1More
Glutathionehsa04064NF-kappa B signaling pathway4.09E-038P10415, O00463, Q04759, Q9UDY8, Q16548, Q13315, P24522, P09341BCL2, TRAF5, PRKCQ, MALT1, BCL2A1, ATM, GADD45A, CXCL1More
Glutathionehsa04071Sphingolipid signaling pathway1.90E-037P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Glutathionehsa04080Neuroactive ligand-receptor interaction1.00E-027P08311, Q15722, P21453, Q9H228, O00398, P21730, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, ADRB2More
Glutathionehsa04140Autophagy - animal3.19E-024P22694, Q14643, P10415, Q04759PRKACB, ITPR1, BCL2, PRKCQMore
Glutathionehsa04145Phagosome4.48E-025Q15080, P05164, O60603, P35443, P13765NCF4, MPO, TLR2, THBS4, HLA-DOBMore
Glutathionehsa04210Apoptosis3.44E-027Q13315, P10415, O76075, P24522, Q16548, P43234, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ITPR1More
Glutathionehsa04217Necroptosis1.37E-026P01568, Q13489, P98170, P08238, P15104, P21796IFNA21, BIRC3, BIRC4, HSP90AB1, GLUL, VDAC1More
Glutathionehsa04340Hedgehog signaling pathway2.62E-034P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Glutathionehsa04371Apelin signaling pathway5.99E-057P62873, P63218, P50151, Q13485, P84022, Q16566, P0DP23GNB1, GNG5, GNG10, SMAD4, SMAD3, CAMK4, CALM1More
Glutathionehsa04390Hippo signaling pathway4.35E-022P63261, O15105ACTG1, SMAD7More
Glutathionehsa04530Tight junction4.35E-022P63261, Q92974ACTG1, ARHGEF2More
Glutathionehsa04610Complement and coagulation cascades3.92E-034P01042, P09871, P0C0L4, P11215KNG1, C1S, C4A, ITGAMMore
Glutathionehsa04612Antigen processing and presentation3.22E-038P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Glutathionehsa04613Neutrophil extracellular trap formation5.80E-0313O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Glutathionehsa04621NOD-like receptor signaling pathway2.62E-0211Q16539, Q14643, P10599, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P09341, P12838MAPK14, ITPR1, TXN, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CXCL1, DEFA4More
Glutathionehsa04650Natural killer cell mediated cytotoxicity2.96E-026O60880, P20963, Q13241, P26718, P26717, P26715SH2D1A, CD247, KLRD1, KLRK1, KLRC2, KLRC1More
Glutathionehsa04657IL-17 signaling pathway3.91E-027O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Glutathionehsa04658Th1 and Th2 cell differentiation5.80E-058Q04759, P20963, P09693, Q16539, Q14765, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, MAPK14, STAT4, GATA3, TBX21, HLA-DOBMore
Glutathionehsa04659Th17 cell differentiation1.90E-026Q04759, P13765, Q9UL17, P23771, P09693, P20963PRKCQ, HLA-DOB, TBX21, GATA3, CD3G, CD247More
Glutathionehsa04660T cell receptor signaling pathway1.40E-0412P01375, Q9UDY8, Q04759, P10747, O95267, Q08881, P20963, P09693, P01732, Q13191, Q16539, P49841TNF, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, MAPK14, GSK3BMore
Glutathionehsa04713Circadian entrainment1.78E-035O15399, P0DP23, P62873, P63218, P50151GRIN2D, CALM1, GNB1, GNG5, GNG10More
Glutathionehsa04720Long-term potentiation9.60E-043Q16566, P0DP23, O15399CAMK4, CALM1, GRIN2DMore
Glutathionehsa04724Glutamatergic synapse1.66E-046O15399, P62873, P63218, P50151, P15104, Q9NSB8GRIN2D, GNB1, GNG5, GNG10, GLUL, HOMER2More
Glutathionehsa04725Cholinergic synapse9.51E-034P62873, P63218, P50151, Q16566GNB1, GNG5, GNG10, CAMK4More
Glutathionehsa04726Serotonergic synapse2.38E-024P62873, P63218, P50151, P09917GNB1, GNG5, GNG10, ALOX5More
Glutathionehsa04727GABAergic synapse2.45E-034P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Glutathionehsa04744Phototransduction6.94E-032P62873, P0DP23GNB1, CALM1More
Glutathionehsa04918Thyroid hormone synthesis3.62E-021P22352GPX3More
Glutathionehsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Glutathionehsa04924Renin secretion1.04E-023P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Glutathionehsa04925Aldosterone synthesis and secretion3.44E-023P0DP23, Q16566, P23634CALM1, CAMK4, ATP2B4More
Glutathionehsa04928Parathyroid hormone synthesis, secretion and action4.23E-024Q14643, P22694, P23771, P10415ITPR1, PRKACB, GATA3, BCL2More
Glutathionehsa04940Type I diabetes mellitus4.80E-023P01889, P10321, P01584HLA-B, HLA-C, IL1BMore
Glutathionehsa04962Vasopressin-regulated water reabsorption3.77E-021Q9UJW0DCTN4More
Glutathionehsa05010Alzheimer disease2.57E-0311O15239, P05496, Q06055, P04406, P01584, P18848, O15169, P67870, P28070, P43686, P62195NDUFA1, ATP5G1, ATP5G2, GAPDH, IL1B, ATF4, AXIN1, CSNK2B, PSMB4, PSMC4, PSMC5More
Glutathionehsa05012Parkinson disease2.21E-022Q06055, P62195ATP5G2, PSMC5More
Glutathionehsa05014Amyotrophic lateral sclerosis8.23E-0310O15239, P05496, Q06055, P18848, P28070, P43686, P62195, P51991, P35658, Q9UBU9NDUFA1, ATP5G1, ATP5G2, ATF4, PSMB4, PSMC4, PSMC5, HNRPA3, NUP214, NXF1More
Glutathionehsa05016Huntington disease2.48E-022Q06055, P62195ATP5G2, PSMC5More
Glutathionehsa05020Prion disease6.90E-0310P01584, P46531, O15239, P05496, Q06055, P18848, P28070, P43686, P62195, P67870IL1B, NOTCH1, NDUFA1, ATP5G1, ATP5G2, ATF4, PSMB4, PSMC4, PSMC5, CSNK2BMore
Glutathionehsa05022Pathways of neurodegeneration - multiple diseases1.04E-0211P67870, O15239, P05496, Q06055, P18848, O15169, P01584, Q13557, P28070, P43686, P62195CSNK2B, NDUFA1, ATP5G1, ATP5G2, ATF4, AXIN1, IL1B, CAMK2D, PSMB4, PSMC4, PSMC5More
Glutathionehsa05032Morphine addiction1.34E-024P62873, P63218, P50151, P43250GNB1, GNG5, GNG10, GRK6More
Glutathionehsa05034Alcoholism1.28E-049O15399, Q16566, P0DP23, P62873, P63218, P50151, Q93079, O60814, P68431GRIN2D, CAMK4, CALM1, GNB1, GNG5, GNG10, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Glutathionehsa05133Pertussis1.33E-046P11215, P0DP23, P10145, P23528, P09871, P0C0L4ITGAM, CALM1, IL8, CFL1, C1S, C4AMore
Glutathionehsa05140Leishmaniasis1.87E-027P13612, O75015, P13765, O60603, P01375, Q16539, Q15080ITGA4, FCGR3B, HLA-DOB, TLR2, TNF, MAPK14, NCF4More
Glutathionehsa05143African trypanosomiasis4.90E-022Q16363, P01584LAMA4, IL1BMore
Glutathionehsa05146Amoebiasis3.91E-027P09341, P27930, P01375, O60603, P05089, P22694, P08311CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSGMore
Glutathionehsa05163Human cytomegalovirus infection2.00E-026P62873, P63218, P50151, P0DP23, P30101, P01568GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21More
Glutathionehsa05167Kaposi sarcoma-associated herpesvirus infection2.00E-026P01568, P62873, P63218, P50151, P07948, P0DP23IFNA21, GNB1, GNG5, GNG10, LYN, CALM1More
Glutathionehsa05168Herpes simplex virus 1 infection4.43E-028P01568, Q07955, P84103, Q13243, Q13489, P30101, Q13398, Q9NZL3IFNA21, SFRS1, SFRS3, SFRS5, BIRC3, PDIA3, ZNF211, ZNF224More
Glutathionehsa05170Human immunodeficiency virus 1 infection1.83E-027P62873, P63218, P50151, P0DP23, P30101, P01568, P23528GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21, CFL1More
Glutathionehsa05171Coronavirus disease - COVID-193.87E-045P62249, P40429, P27635, Q07020, P05386RPS16, RPL13A, RPL10, RPL18, RPLP1More
Glutathionehsa05200Pathways in cancer3.99E-0415Q13751, P08238, P43246, P84022, Q13485, Q13489, P98170, P62873, P63218, P50151, P78417, O75293, P0DP23, P01568, P01042LAMB3, HSP90AB1, MSH2, SMAD3, SMAD4, BIRC3, BIRC4, GNB1, GNG5, GNG10, GSTO1, GADD45B, CALM1, IFNA21, KNG1More
Glutathionehsa05202Transcriptional misregulation in cancer1.23E-0417Q12778, Q13315, O94812, P14780, P27930, Q15744, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P12980, P24522FOXO1, ATM, BAIAP3, MMP9, IL1R2, CEBPE, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, LYL1, GADD45AMore
Glutathionehsa05203Viral carcinogenesis8.68E-048Q12933, P18848, P42229, P27348, Q15283, P01889, P10321, P61978TRAF2, ATF4, STAT5A, YWHAQ, RASA2, HLA-B, HLA-C, HNRPKMore
Glutathionehsa05204Chemical carcinogenesis6.91E-054Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
Glutathionehsa05210Colorectal cancer4.67E-024P84022, Q13485, P43246, O75293SMAD3, SMAD4, MSH2, GADD45BMore
Glutathionehsa05212Pancreatic cancer3.28E-023P84022, Q13485, O75293SMAD3, SMAD4, GADD45BMore
Glutathionehsa05214Glioma3.28E-023P0DP23, Q16566, O75293CALM1, CAMK4, GADD45BMore
Glutathionehsa05222Small cell lung cancer3.80E-024Q13751, Q13489, P98170, O75293LAMB3, BIRC3, BIRC4, GADD45BMore
Glutathionehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer2.84E-025P20963, P09693, O60603, P10747, Q04759CD247, CD3G, TLR2, CD28, PRKCQMore
Glutathionehsa05310Asthma2.81E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Glutathionehsa05321Inflammatory bowel disease1.22E-056O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Glutathionehsa05323Rheumatoid arthritis1.60E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Glutathionehsa05332Graft-versus-host disease8.59E-058P13765, P01889, P10321, P10747, P01375, P01584, P26715, Q13241HLA-DOB, HLA-B, HLA-C, CD28, TNF, IL1B, KLRC1, KLRD1More
Glutathionehsa05415Diabetic cardiomyopathy1.09E-022Q06055, P04406ATP5G2, GAPDHMore

Community members of Glutathione (SDC: 3.05)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P10768ESDSNoneformylglutathione hydrolaseReported00.22210.00670.25340.3778
P36969GPX4Phospholipid hydroperoxide glutathione peroxidaseReported00.66910.01570.25190.6179
Q16772GSTA3Glutathione SNonetransferase A3Reported00.46240.03360.4250.7234
P09211GSTP1Glutathione SNonetransferase PReported00.32040.35230.45661.3213
P78417GSTO1Glutathione SNonetransferase omegaNone1Reported00.41090.13990.4250.9103
P22352GPX3Glutathione peroxidase 3Reported00.32460.01640.36170.5568
P15121AKR1B1AldoNoneketo reductase family 1 member B1Reported10.56830.6290.2141.7562
P14780MMP9Matrix metalloproteinaseNone9Reported10.16960.84240.73152.5012
Q96KQ7EHMT2HistoneNonelysine NNonemethyltransferase EHMT2Predicted00.07280.21650.29090.7603
Q14390GGTLC2Glutathione hydrolase light chain 2Predicted00.04590.00600.035
P14550AKR1A1AldoNoneketo reductase family 1 member A1Predicted10.30560.06210.17370.4508
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
Q9UJ14GGTL3Glutathione hydrolase 7Predicted00.54780.00230.19890.4774
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)