PharmaCoNets of Glucosamine (SPCN: 1.57 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Glucosaminehsa00514Other types of O-glycan biosynthesis3.20E-022O15294, Q9NY28OGT, GALNT8More
Glucosaminehsa00980Metabolism of xenobiotics by cytochrome P4503.20E-022P78417, P11712GSTO1, CYP2C9More
Glucosaminehsa00982Drug metabolism - cytochrome P4503.20E-022P11712, P78417CYP2C9, GSTO1More
Glucosaminehsa01524Platinum drug resistance3.62E-024Q13489, P98170, P78417, P43246BIRC3, BIRC4, GSTO1, MSH2More
Glucosaminehsa04014Ras signaling pathway4.38E-025P20827, P49767, Q14644, P0DP23, P62873EFNA1, VEGFC, RASA3, CALM1, GNB1More
Glucosaminehsa04071Sphingolipid signaling pathway4.56E-026Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Glucosaminehsa04340Hedgehog signaling pathway3.46E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Glucosaminehsa04371Apelin signaling pathway9.26E-035P62873, Q13485, P84022, Q16566, P0DP23GNB1, SMAD4, SMAD3, CAMK4, CALM1More
Glucosaminehsa04612Antigen processing and presentation3.25E-038P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Glucosaminehsa04613Neutrophil extracellular trap formation3.61E-0213O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Glucosaminehsa04621NOD-like receptor signaling pathway1.90E-0314Q16539, Q14643, P10599, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P09341, P49913, P59665, P59666, P12838MAPK14, ITPR1, TXN, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Glucosaminehsa04650Natural killer cell mediated cytotoxicity1.25E-028P01375, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Glucosaminehsa04657IL-17 signaling pathway4.78E-0311P08238, O00463, Q07955, Q16539, P49841, P09341, P14780, Q9UJX4, P04141, P80188, P01375HSP90AB1, TRAF5, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, ANAPC5, CSF2, LCN2, TNFMore
Glucosaminehsa04658Th1 and Th2 cell differentiation1.12E-028Q04759, P20963, P09693, Q16539, Q14765, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, MAPK14, STAT4, GATA3, TBX21, HLA-DOBMore
Glucosaminehsa04660T cell receptor signaling pathway3.76E-0311P01375, Q9UDY8, Q04759, O95267, Q08881, P20963, P09693, P01732, Q13191, Q16539, P49841TNF, MALT1, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, MAPK14, GSK3BMore
Glucosaminehsa04744Phototransduction5.92E-032P62873, P0DP23GNB1, CALM1More
Glucosaminehsa04933AGE-RAGE signaling pathway in diabetic complications2.33E-024P84022, Q13485, Q12778, P49767SMAD3, SMAD4, FOXO1, VEGFCMore
Glucosaminehsa05034Alcoholism4.38E-025Q16566, P0DP23, P62873, O60814, P68431CAMK4, CALM1, GNB1, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Glucosaminehsa05133Pertussis1.88E-023P11215, P0DP23, P23528ITGAM, CALM1, CFL1More
Glucosaminehsa05140Leishmaniasis1.87E-027P13612, O75015, P13765, O60603, P01375, Q16539, Q15080ITGA4, FCGR3B, HLA-DOB, TLR2, TNF, MAPK14, NCF4More
Glucosaminehsa05144Malaria3.12E-024P60033, P01375, P35443, P26718CD81, TNF, THBS4, KLRK1More
Glucosaminehsa05146Amoebiasis3.91E-027P09341, P27930, P01375, O60603, P05089, P22694, P08311CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSGMore
Glucosaminehsa05150Staphylococcus aureus infection1.02E-037P21730, P21462, O75015, P59665, P59666, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Glucosaminehsa05200Pathways in cancer6.17E-0312Q13751, P08238, P43246, P84022, Q13485, Q13489, P98170, P49767, Q12778, P62873, P78417, P0DP23LAMB3, HSP90AB1, MSH2, SMAD3, SMAD4, BIRC3, BIRC4, VEGFC, FOXO1, GNB1, GSTO1, CALM1More
Glucosaminehsa05202Transcriptional misregulation in cancer3.00E-0213P14780, P27930, Q15744, Q16548, Q13077, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P12980, P24522MMP9, IL1R2, CEBPE, BCL2A1, TRAF1, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, LYL1, GADD45AMore
Glucosaminehsa05310Asthma2.81E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Glucosaminehsa05321Inflammatory bowel disease3.16E-036O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Glucosaminehsa05332Graft-versus-host disease3.46E-024P13765, P01375, P26715, Q13241HLA-DOB, TNF, KLRC1, KLRD1More
N-Acetylglucosaminehsa00052Galactose metabolism7.59E-031P15291B4GALT1More
N-Acetylglucosaminehsa00220Arginine biosynthesis3.52E-022P05089, P49448ARG1, GLUD2More
N-Acetylglucosaminehsa00500Starch and sucrose metabolism1.18E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
N-Acetylglucosaminehsa00510N-Glycan biosynthesis6.07E-031P15291B4GALT1More
N-Acetylglucosaminehsa00513Various types of N-glycan biosynthesis3.03E-031P15291B4GALT1More
N-Acetylglucosaminehsa00514Other types of O-glycan biosynthesis3.03E-031P15291B4GALT1More
N-Acetylglucosaminehsa00515Mannose type O-glycan biosynthesis1.52E-031P15291B4GALT1More
N-Acetylglucosaminehsa00520Amino sugar and nucleotide sugar metabolism6.27E-032Q13231, Q9Y5P6CHIT1, GMPPBMore
N-Acetylglucosaminehsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.52E-031P15291B4GALT1More
N-Acetylglucosaminehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.03E-031P15291B4GALT1More
N-Acetylglucosaminehsa01240Biosynthesis of cofactors2.98E-022Q92820, Q9Y5P6GGH, GMPPBMore
N-Acetylglucosaminehsa01524Platinum drug resistance4.94E-022O15392, P11388BIRC5, TOP2AMore
N-Acetylglucosaminehsa03320PPAR signaling pathway6.51E-043P78380, Q13133, Q02318OLR1, NR1H3, CYP27A1More
N-Acetylglucosaminehsa04060Cytokine-cytokine receptor interaction1.04E-0312P32927, P27930, P14778, Q13651, P25024, P25025, Q9UBD3, P47992, P09341, P32248, P18510, P01730CSF2RB, IL1R2, IL1R1, IL10RA, CXCR1, CXCR2, XCL2, XCL1, CXCL1, CCR7, IL1RN, CD4More
N-Acetylglucosaminehsa04061Viral protein interaction with cytokine and cytokine receptor2.11E-037P32248, P09341, P25024, P25025, P47992, Q9UBD3, Q13651CCR7, CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RAMore
N-Acetylglucosaminehsa04064NF-kappa B signaling pathway2.03E-027O00463, P14778, Q04759, Q16548, P06239, P24522, P09341TRAF5, IL1R1, PRKCQ, BCL2A1, LCK, GADD45A, CXCL1More
N-Acetylglucosaminehsa04115p53 signaling pathway3.91E-022P31350, P06493RRM2, CDK1More
N-Acetylglucosaminehsa04210Apoptosis1.40E-028P04637, O76075, P32927, P24522, Q16548, P43234, Q9UBR2, Q14643TP53, DFFB, CSF2RB, GADD45A, BCL2A1, CTSO, CTSZ, ITPR1More
N-Acetylglucosaminehsa04621NOD-like receptor signaling pathway4.30E-027Q16539, Q14643, P10599, P43490, O00463, P29728, P09341MAPK14, ITPR1, TXN, PBEF1, TRAF5, OAS2, CXCL1More
N-Acetylglucosaminehsa04640Hematopoietic cell lineage6.35E-049P13612, P14778, P27930, P20023, P11836, P07766, P09693, P01730, P13765ITGA4, IL1R1, IL1R2, CR2, MS4A1, CD3E, CD3G, CD4, HLA-DOBMore
N-Acetylglucosaminehsa04658Th1 and Th2 cell differentiation2.04E-048Q04759, P07766, P09693, Q16539, P01730, P06239, P23771, P13765PRKCQ, CD3E, CD3G, MAPK14, CD4, LCK, GATA3, HLA-DOBMore
N-Acetylglucosaminehsa04659Th17 cell differentiation1.91E-049Q04759, Q16539, P01730, P06239, P13765, P14778, P23771, P07766, P09693PRKCQ, MAPK14, CD4, LCK, HLA-DOB, IL1R1, GATA3, CD3E, CD3GMore
N-Acetylglucosaminehsa04660T cell receptor signaling pathway1.29E-027Q04759, O95267, P07766, P09693, P01730, P06239, Q16539PRKCQ, RASGRP1, CD3E, CD3G, CD4, LCK, MAPK14More
N-Acetylglucosaminehsa04750Inflammatory mediator regulation of TRP channels3.71E-024P14778, Q16539, Q14643, Q04759IL1R1, MAPK14, ITPR1, PRKCQMore
N-Acetylglucosaminehsa05120Epithelial cell signaling in Helicobacter pylori infection1.88E-024Q16539, P09341, P25024, P25025MAPK14, CXCL1, CXCR1, CXCR2More
N-Acetylglucosaminehsa05131Shigellosis4.08E-028O00463, P14778, Q16539, Q04759, Q9NQL2, P12814, Q14643, P04637TRAF5, IL1R1, MAPK14, PRKCQ, RRAGD, ACTN1, ITPR1, TP53More
N-Acetylglucosaminehsa05146Amoebiasis3.40E-025P09341, P14778, P27930, P05089, P12814CXCL1, IL1R1, IL1R2, ARG1, ACTN1More
N-Acetylglucosaminehsa05163Human cytomegalovirus infection2.49E-027Q14643, P14778, Q13651, P25025, Q16539, P04637, O00463ITPR1, IL1R1, IL10RA, CXCR2, MAPK14, TP53, TRAF5More
N-Acetylglucosaminehsa05166Human T-cell leukemia virus 1 infection3.05E-0210O60566, P14778, P27930, P07766, P09693, P13765, P42773, P06239, P01730, P04637BUB1B, IL1R1, IL1R2, CD3E, CD3G, HLA-DOB, CDKN2C, LCK, CD4, TP53More
N-Acetylglucosaminehsa05169Epstein-Barr virus infection1.18E-029P20023, P13765, P04637, O00463, Q16539, P24522, P29728, P07766, P09693CR2, HLA-DOB, TP53, TRAF5, MAPK14, GADD45A, OAS2, CD3E, CD3GMore
N-Acetylglucosaminehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.42E-037O95267, P07766, P09693, P06239, Q04759, Q16539, P01730RASGRP1, CD3E, CD3G, LCK, PRKCQ, MAPK14, CD4More

Community members of Glucosamine (SDC: 0.39)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P01375TNFTumor necrosis factorReported10.18650.55112.1953
P14780MMP9Matrix metalloproteinaseNone9Reported10.16960.84240.73152.5012
O75832PSMD1026S proteasome nonNoneATPase regulatory subunit 10Predicted00.21030.018500.1422
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)