PharmaCoNets of Fusidic-acid (SPCN: 15.54 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Fusidic-acidhsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Fusidic-acidhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Fusidic-acidhsa00190Oxidative phosphorylation4.36E-033Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Fusidic-acidhsa00340Histidine metabolism4.52E-021O95954FTCDMore
Fusidic-acidhsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Fusidic-acidhsa00500Starch and sucrose metabolism1.79E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
Fusidic-acidhsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Fusidic-acidhsa00564Glycerophospholipid metabolism9.70E-032Q9Y259, P49619CHKB, DGKGMore
Fusidic-acidhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Fusidic-acidhsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Fusidic-acidhsa00730Thiamine metabolism4.66E-022P05186, P24666ALPL, ACP1More
Fusidic-acidhsa00770Pantothenate and CoA biosynthesis7.90E-033O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Fusidic-acidhsa00970Aminoacyl-tRNA biosynthesis7.90E-033O95363, P54136, Q15046FARS2, RARS1, KARSMore
Fusidic-acidhsa00980Metabolism of xenobiotics by cytochrome P4505.46E-032Q16772, P09211GSTA3, GSTP1More
Fusidic-acidhsa00982Drug metabolism - cytochrome P4501.06E-022Q16772, P09211GSTA3, GSTP1More
Fusidic-acidhsa00983Drug metabolism - other enzymes1.72E-022Q16772, P09211GSTA3, GSTP1More
Fusidic-acidhsa01100Metabolic pathways5.23E-0418P35790, Q9Y259, Q16772, P09211, Q9UJ14, P30041, Q13956, P40926, Q7KZN9, P15121, P49619, O95954, Q02318, Q9UHK6, Q86VZ5, Q9UBX8, P35573, Q9BQB6CHKA, CHKB, GSTA3, GSTP1, GGTL3, PRDX6, PDE6H, MDH2, COX15, AKR1B1, DGKG, FTCD, CYP27A1, AMACR, SGMS1, B4GALT6, AGL, VKORC1More
Fusidic-acidhsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Fusidic-acidhsa01230Biosynthesis of amino acids3.91E-023P51854, Q99707, P50213TKTL1, MTR, IDH3AMore
Fusidic-acidhsa01524Platinum drug resistance4.44E-022Q16772, P09211GSTA3, GSTP1More
Fusidic-acidhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Fusidic-acidhsa03320PPAR signaling pathway1.62E-022Q13133, Q02318NR1H3, CYP27A1More
Fusidic-acidhsa04062Chemokine signaling pathway3.93E-0310P25024, P25025, P47992, Q9UBD3, P07948, P63218, P50151, P49407, Q08881, P49841CXCR1, CXCR2, XCL1, XCL2, LYN, GNG5, GNG10, ARRB1, ITK, GSK3BMore
Fusidic-acidhsa04110Cell cycle3.57E-023Q9UBD5, P06493, P33981ORC3, CDK1, TTKMore
Fusidic-acidhsa04390Hippo signaling pathway4.35E-022P63261, O15105ACTG1, SMAD7More
Fusidic-acidhsa04530Tight junction4.35E-022P63261, Q92974ACTG1, ARHGEF2More
Fusidic-acidhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Fusidic-acidhsa04612Antigen processing and presentation4.78E-026P48382, P26715, P26717, Q13241, O43908, P01375RFX5, KLRC1, KLRC2, KLRD1, KLRC4, TNFMore
Fusidic-acidhsa04621NOD-like receptor signaling pathway2.27E-029Q9H1Y0, P43490, O00463, Q05823, P01375, P49913, P59665, P59666, P12838ATG5, PBEF1, TRAF5, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Fusidic-acidhsa04650Natural killer cell mediated cytotoxicity6.22E-059P01375, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Fusidic-acidhsa04660T cell receptor signaling pathway2.78E-027P01375, Q08881, P20963, Q13191, P06239, Q16539, P49841TNF, ITK, CD247, CBLB, LCK, MAPK14, GSK3BMore
Fusidic-acidhsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Fusidic-acidhsa04728Dopaminergic synapse2.82E-026P14416, P63218, P50151, P49841, Q16539, P49407DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1More
Fusidic-acidhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Fusidic-acidhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Fusidic-acidhsa05120Epithelial cell signaling in Helicobacter pylori infection3.11E-024Q16539, P25024, P25025, P07948MAPK14, CXCR1, CXCR2, LYNMore
Fusidic-acidhsa05133Pertussis4.20E-021P0C0L4C4AMore
Fusidic-acidhsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Fusidic-acidhsa05140Leishmaniasis4.50E-035P14598, O60603, P25963, P29350, Q15080NCF1, TLR2, NFKBIA, PTPN6, NCF4More
Fusidic-acidhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Fusidic-acidhsa05144Malaria2.08E-046P60033, P69905, P68871, P01375, P35443, P26718CD81, HBA2, HBB, TNF, THBS4, KLRK1More
Fusidic-acidhsa05150Staphylococcus aureus infection1.02E-037P21730, P21462, O75015, P59665, P59666, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Fusidic-acidhsa05163Human cytomegalovirus infection1.72E-028P01375, P63218, P50151, P49841, P14778, P25025, Q16539, O00463TNF, GNG5, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5More
Fusidic-acidhsa05203Viral carcinogenesis4.62E-023Q12933, P42229, Q15283TRAF2, STAT5A, RASA2More
Fusidic-acidhsa05204Chemical carcinogenesis5.46E-032Q16772, P09211GSTA3, GSTP1More
Fusidic-acidhsa05231Choline metabolism in cancer2.00E-022Q9Y259, P49619CHKB, DGKGMore
Fusidic-acidhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Fusidic-acidhsa05418Fluid shear stress and atherosclerosis3.61E-026Q16539, P10599, P14780, P01375, P14778, P27930MAPK14, TXN, MMP9, TNF, IL1R1, IL1R2More

Community members of Fusidic-acid (SDC: 3.65)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)