| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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| Fosphenytoin | hsa00220 | Arginine biosynthesis | 1.54E-02 | 2 | P05089, P49448 | ARG1, GLUD2 | More | | | Fosphenytoin | hsa00910 | Nitrogen metabolism | 2.93E-02 | 2 | P22748, P49448 | CA4, GLUD2 | More | | | Fosphenytoin | hsa00983 | Drug metabolism - other enzymes | 3.20E-02 | 3 | P04183, P32320, P05164 | TK1, CDA, MPO | More | | | Fosphenytoin | hsa04060 | Cytokine-cytokine receptor interaction | 5.39E-03 | 10 | P27930, P08476, Q13651, Q9HBE5, Q9UBD3, P47992, P01375, P09341, P18510, Q93038 | IL1R2, INHBA, IL10RA, IL21R, XCL2, XCL1, TNF, CXCL1, IL1RN, TNFRSF25 | More | | | Fosphenytoin | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 4.34E-02 | 5 | P09341, P47992, Q9UBD3, Q13651, P01375 | CXCL1, XCL1, XCL2, IL10RA, TNF | More | | | Fosphenytoin | hsa04064 | NF-kappa B signaling pathway | 6.00E-03 | 8 | O00463, P01375, Q04759, Q16548, P06239, Q13315, P24522, P09341 | TRAF5, TNF, PRKCQ, BCL2A1, LCK, ATM, GADD45A, CXCL1 | More | | | Fosphenytoin | hsa04612 | Antigen processing and presentation | 9.89E-03 | 7 | P13765, P48382, P26715, P26717, Q13241, P01732, P01375 | HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8A, TNF | More | | | Fosphenytoin | hsa04640 | Hematopoietic cell lineage | 4.96E-02 | 6 | P27930, P25063, P09693, P01732, P13765, P01375 | IL1R2, CD24, CD3G, CD8A, HLA-DOB, TNF | More | | | Fosphenytoin | hsa04650 | Natural killer cell mediated cytotoxicity | 2.94E-03 | 8 | P01375, P06239, O60880, P20963, Q13241, P26718, P26717, P26715 | TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, KLRC2, KLRC1 | More | | | Fosphenytoin | hsa04657 | IL-17 signaling pathway | 2.29E-02 | 5 | O00463, P09341, P14780, P80188, P01375 | TRAF5, CXCL1, MMP9, LCN2, TNF | More | | | Fosphenytoin | hsa04658 | Th1 and Th2 cell differentiation | 1.26E-03 | 8 | Q04759, P20963, P09693, P06239, Q14765, P23771, Q9UL17, P13765 | PRKCQ, CD247, CD3G, LCK, STAT4, GATA3, TBX21, HLA-DOB | More | | | Fosphenytoin | hsa04659 | Th17 cell differentiation | 3.55E-03 | 8 | Q04759, P06239, P13765, Q9HBE5, Q9UL17, P23771, P09693, P20963 | PRKCQ, LCK, HLA-DOB, IL21R, TBX21, GATA3, CD3G, CD247 | More | | | Fosphenytoin | hsa04660 | T cell receptor signaling pathway | 2.94E-03 | 8 | P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, P06239 | TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, LCK | More | | | Fosphenytoin | hsa04964 | Proximal tubule bicarbonate reclamation | 2.93E-02 | 2 | P22748, P49448 | CA4, GLUD2 | More | | | Fosphenytoin | hsa05146 | Amoebiasis | 7.00E-03 | 7 | P09341, P27930, P01375, P05089, P22694, P12814, P08311 | CXCL1, IL1R2, TNF, ARG1, PRKACB, ACTN1, CTSG | More | | | Fosphenytoin | hsa05202 | Transcriptional misregulation in cancer | 6.16E-03 | 10 | Q13315, P14780, P27930, Q15744, Q16548, P05164, P12838, P08246, Q9C0K0, P24522 | ATM, MMP9, IL1R2, CEBPE, BCL2A1, MPO, DEFA4, ELA2, BCL11B, GADD45A | More | | | Fosphenytoin | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 4.34E-02 | 5 | O95267, P20963, P09693, P06239, Q04759 | RASGRP1, CD247, CD3G, LCK, PRKCQ | More | | | Fosphenytoin | hsa05310 | Asthma | 3.20E-02 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | | Fosphenytoin | hsa05321 | Inflammatory bowel disease | 1.25E-03 | 6 | P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5 | TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21R | More | | | Fosphenytoin | hsa05322 | Systemic lupus erythematosus | 3.90E-02 | 6 | P08246, P08311, P01375, P13765, Q16778, P12814 | ELA2, CTSG, TNF, HLA-DOB, HIST2H2BE, ACTN1 | More | | | Fosphenytoin | hsa05332 | Graft-versus-host disease | 2.55E-02 | 4 | P13765, P01375, P26715, Q13241 | HLA-DOB, TNF, KLRC1, KLRD1 | More | |
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