PharmaCoNets of Flufenamic-acid (SPCN: 109.75 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Flufenamic-acidhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Flufenamic-acidhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Flufenamic-acidhsa00190Oxidative phosphorylation1.94E-023Q16718, P36542, O14521NDUFA5, ATP5C1, SDHDMore
Flufenamic-acidhsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Flufenamic-acidhsa00500Starch and sucrose metabolism2.41E-043O43451, P46976, P06737MGAM, GYG1, PYGLMore
Flufenamic-acidhsa00510N-Glycan biosynthesis1.00E-022O94777, Q9BVK2DPM2, ALG8More
Flufenamic-acidhsa00520Amino sugar and nucleotide sugar metabolism2.11E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Flufenamic-acidhsa00561Glycerolipid metabolism3.09E-022P14550, Q86XP1AKR1A1, DGKHMore
Flufenamic-acidhsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.47E-032O94777, Q14442DPM2, PIGHMore
Flufenamic-acidhsa00565Ether lipid metabolism1.61E-042Q9Y6K0, Q8N661CEPT1, TMEM86BMore
Flufenamic-acidhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Flufenamic-acidhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Flufenamic-acidhsa00600Sphingolipid metabolism4.47E-022Q96G23, Q86VZ5LASS2, SGMS1More
Flufenamic-acidhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series8.72E-032P06865, O75752HEXA, B3GALNT1More
Flufenamic-acidhsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Flufenamic-acidhsa00620Pyruvate metabolism3.19E-022P40926, P14550MDH2, AKR1A1More
Flufenamic-acidhsa00630Glyoxylate and dicarboxylate metabolism6.56E-052P40925, P15104MDH1, GLULMore
Flufenamic-acidhsa00730Thiamine metabolism1.81E-032P05186, P24666ALPL, ACP1More
Flufenamic-acidhsa00770Pantothenate and CoA biosynthesis7.90E-033O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Flufenamic-acidhsa00970Aminoacyl-tRNA biosynthesis7.90E-033O95363, P54136, Q15046FARS2, RARS1, KARSMore
Flufenamic-acidhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-054Q16772, P78417, P09211, P11712GSTA3, GSTO1, GSTP1, CYP2C9More
Flufenamic-acidhsa00982Drug metabolism - cytochrome P4501.77E-044P11712, Q16772, P09211, P78417CYP2C9, GSTA3, GSTP1, GSTO1More
Flufenamic-acidhsa00983Drug metabolism - other enzymes1.92E-035P04183, P32320, P05164, Q16772, P09211TK1, CDA, MPO, GSTA3, GSTP1More
Flufenamic-acidhsa01100Metabolic pathways2.14E-0524Q9Y234, P35790, Q16772, P09211, Q9UJ14, P30041, Q6ZQY3, P20839, P40926, O94777, Q7KZN9, Q9Y6K0, P15121, Q86XP1, P14550, Q9UHK6, Q86VZ5, Q96G23, Q9BVK2, Q14442, Q9BQB6, Q06055, Q99437, Q9NVH6LIPT1, CHKA, GSTA3, GSTP1, GGTL3, PRDX6, GADL1, IMPDH1, MDH2, DPM2, COX15, CEPT1, AKR1B1, DGKH, AKR1A1, AMACR, SGMS1, LASS2, ALG8, PIGH, VKORC1, ATP5G2, ATP6V0B, TMLHEMore
Flufenamic-acidhsa01523Antifolate resistance3.80E-022Q92820, P04818GGH, TYMSMore
Flufenamic-acidhsa01524Platinum drug resistance4.44E-022Q16772, P09211GSTA3, GSTP1More
Flufenamic-acidhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Flufenamic-acidhsa03010Ribosome1.88E-026P62753, P25398, P32969, P62829, P18077, P36578RPS6, RPS12, RPL9, RPL23, RPL35A, RPL4More
Flufenamic-acidhsa03013RNA transport1.39E-0412O14980, Q09161, O14893, Q7Z3B4, P35658, P47813, Q14152, O75822, Q14240, Q9BZI7, Q06787, P51114XPO1, NCBP1, GEMIN2, NUP54, NUP214, EIF1AX, EIF3A, EIF3J, EIF4A2, UPF3B, FMR1, FXR1More
Flufenamic-acidhsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Flufenamic-acidhsa03022Basal transcription factors3.50E-023P20226, O00268, Q15544TBP, TAF4, TAF11More
Flufenamic-acidhsa03040Spliceosome9.73E-0610Q14562, O43143, O60508, P08579, Q07955, Q01130, Q13243, P11142, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, SFRS1, SFRS2, SFRS5, HSPA8, PPIH, ASCC3L1More
Flufenamic-acidhsa04012ErbB signaling pathway1.34E-024P16333, P19174, P42338, P01106NCK1, PLCG1, PIK3CB, MYCMore
Flufenamic-acidhsa04014Ras signaling pathway2.92E-0410P42338, P20827, Q9NRA1, P49767, Q13009, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Flufenamic-acidhsa04015Rap1 signaling pathway4.83E-038P20827, Q9NRA1, P49767, P11215, Q13009, P42338, P0DP23, P19174EFNA1, PDGFC, VEGFC, ITGAM, TIAM1, PIK3CB, CALM1, PLCG1More
Flufenamic-acidhsa04020Calcium signaling pathway2.61E-026P27987, P21796, P19174, P0DP23, Q9NRA1, P49767ITPKB, VDAC1, PLCG1, CALM1, PDGFC, VEGFCMore
Flufenamic-acidhsa04024cAMP signaling pathway4.38E-024P42338, P0DP23, Q13370, Q13009PIK3CB, CALM1, PDE3B, TIAM1More
Flufenamic-acidhsa04062Chemokine signaling pathway5.33E-0618P25024, P25025, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q13009, P14598, P42224, P25963, P49841CXCR1, CXCR2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, TIAM1, NCF1, STAT1, NFKBIA, GSK3BMore
Flufenamic-acidhsa04064NF-kappa B signaling pathway2.30E-048P10415, O00463, Q04759, Q9UDY8, Q16548, Q13315, P24522, P09341BCL2, TRAF5, PRKCQ, MALT1, BCL2A1, ATM, GADD45A, CXCL1More
Flufenamic-acidhsa04070Phosphatidylinositol signaling system1.45E-035P19174, P0DP23, P42338, P23743, P27987PLCG1, CALM1, PIK3CB, DGKA, ITPKBMore
Flufenamic-acidhsa04071Sphingolipid signaling pathway1.00E-035P21453, Q9H228, Q13362, Q9BX95, P10415S1PR1, EDG8, PPP2R5C, SGPP1, BCL2More
Flufenamic-acidhsa04072Phospholipase D signaling pathway4.67E-025P42338, P19174, Q14344, P23743, Q9NRA1PIK3CB, PLCG1, GNA13, DGKA, PDGFCMore
Flufenamic-acidhsa04080Neuroactive ligand-receptor interaction1.05E-038P08311, Q15722, P21453, Q9H228, O00398, P21730, Q16581, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, C3AR1, ADRB2More
Flufenamic-acidhsa04110Cell cycle6.80E-036P06493, O75293, P30304, P33981, P42773, P01106CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Flufenamic-acidhsa04114Oocyte meiosis2.05E-025Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Flufenamic-acidhsa04115p53 signaling pathway3.98E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Flufenamic-acidhsa04130SNARE interactions in vesicular transport1.27E-021O15155BET1More
Flufenamic-acidhsa04140Autophagy - animal3.19E-024P22694, Q14643, P10415, Q04759PRKACB, ITPR1, BCL2, PRKCQMore
Flufenamic-acidhsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Flufenamic-acidhsa04145Phagosome4.48E-025Q15080, P05164, O60603, P35443, P13765NCF4, MPO, TLR2, THBS4, HLA-DOBMore
Flufenamic-acidhsa04146Peroxisome4.83E-024O96011, P56589, Q9UKG9, O75521PEX11B, PEX3, CROT, ECI2More
Flufenamic-acidhsa04151PI3K-Akt signaling pathway5.62E-0312P42338, P01106, P20827, Q9NRA1, P49767, P08238, P62873, P63218, P50151, O15335, P14784, P01568PIK3CB, MYC, EFNA1, PDGFC, VEGFC, HSP90AB1, GNB1, GNG5, GNG10, CHAD, IL2RB, IFNA21More
Flufenamic-acidhsa04210Apoptosis3.83E-038Q13315, P10415, O76075, P24522, Q16548, P43234, P18848, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ATF4, ITPR1More
Flufenamic-acidhsa04217Necroptosis4.42E-046P07900, P15104, P05141, P01584, P0C0S5, Q13557HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, CAMK2DMore
Flufenamic-acidhsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Flufenamic-acidhsa04330Notch signaling pathway3.09E-022P49768, P78504PSEN1, JAG1More
Flufenamic-acidhsa04340Hedgehog signaling pathway3.09E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
Flufenamic-acidhsa04360Axon guidance1.49E-036P16333, P20827, O95631, P42338, P23528, P19174NCK1, EFNA1, NTN1, PIK3CB, CFL1, PLCG1More
Flufenamic-acidhsa04370VEGF signaling pathway1.29E-023P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Flufenamic-acidhsa04371Apelin signaling pathway2.41E-037P62873, P63218, P50151, Q13370, Q14814, Q14344, P0DP23GNB1, GNG5, GNG10, PDE3B, MEF2D, GNA13, CALM1More
Flufenamic-acidhsa04380Osteoclast differentiation1.02E-026Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2More
Flufenamic-acidhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Flufenamic-acidhsa04610Complement and coagulation cascades2.38E-041P0C0L4C4AMore
Flufenamic-acidhsa04612Antigen processing and presentation3.90E-036P13765, P48382, P26715, P26717, Q13241, P01732HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8AMore
Flufenamic-acidhsa04613Neutrophil extracellular trap formation3.70E-0419P42338, P19174, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q93077, P62807, Q93079, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, P21730PIK3CB, PLCG1, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, C5AR1More
Flufenamic-acidhsa04620Toll-like receptor signaling pathway4.00E-024P01568, P42224, P25963, P42338IFNA21, STAT1, NFKBIA, PIK3CBMore
Flufenamic-acidhsa04623Cytosolic DNA-sensing pathway3.67E-022P01568, P25963IFNA21, NFKBIAMore
Flufenamic-acidhsa04625C-type lectin receptor signaling pathway2.21E-038Q9ULY5, P42224, P20749, P25963, P01375, P42338, P0DP23, Q16539CLEC4E, STAT1, BCL3, NFKBIA, TNF, PIK3CB, CALM1, MAPK14More
Flufenamic-acidhsa04640Hematopoietic cell lineage3.69E-024P21926, P07766, P01730, P09564CD9, CD3E, CD4, CD7More
Flufenamic-acidhsa04650Natural killer cell mediated cytotoxicity1.46E-049P01375, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Flufenamic-acidhsa04657IL-17 signaling pathway1.14E-037P07900, O00463, Q16539, P49841, P14780, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, MMP9, TNF, IL1BMore
Flufenamic-acidhsa04658Th1 and Th2 cell differentiation3.11E-0513P25963, Q04759, P07766, P20963, P09693, P19174, P42224, Q14765, P23771, Q9UL17, P14784, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, PLCG1, STAT1, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Flufenamic-acidhsa04659Th17 cell differentiation1.97E-0413P25963, Q04759, P19174, P42224, P14784, P13765, P40189, Q9UL17, P23771, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, PLCG1, STAT1, IL2RB, HLA-DOB, IL6ST, TBX21, GATA3, HSP90AB1, CD3E, CD3G, CD247More
Flufenamic-acidhsa04660T cell receptor signaling pathway8.92E-0412P01375, Q9UDY8, Q04759, P10747, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, MALT1, PRKCQ, CD28, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Flufenamic-acidhsa04662B cell receptor signaling pathway1.12E-025P25963, P42338, P07948, P21854, Q8N149NFKBIA, PIK3CB, LYN, CD72, LILRA2More
Flufenamic-acidhsa04664Fc epsilon RI signaling pathway1.29E-037P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5More
Flufenamic-acidhsa04666Fc gamma R-mediated phagocytosis2.34E-035P07948, P42338, P19174, P23528, P14598LYN, PIK3CB, PLCG1, CFL1, NCF1More
Flufenamic-acidhsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
Flufenamic-acidhsa04710Circadian rhythm1.67E-022Q16526, Q9Y478CRY1, PRKAB1More
Flufenamic-acidhsa04713Circadian entrainment4.00E-024P0DP23, P62873, P63218, P50151CALM1, GNB1, GNG5, GNG10More
Flufenamic-acidhsa04721Synaptic vesicle cycle3.09E-022Q99437, P43005ATP6V0B, SLC1A1More
Flufenamic-acidhsa04724Glutamatergic synapse2.92E-024P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Flufenamic-acidhsa04725Cholinergic synapse3.51E-038P22694, Q14643, P62873, P63218, P50151, P18848, P42338, P10415PRKACB, ITPR1, GNB1, GNG5, GNG10, ATF4, PIK3CB, BCL2More
Flufenamic-acidhsa04727GABAergic synapse8.14E-034P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Flufenamic-acidhsa04728Dopaminergic synapse2.82E-026P14416, P63218, P50151, P49841, Q16539, P49407DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1More
Flufenamic-acidhsa04744Phototransduction1.32E-022P62873, P0DP23GNB1, CALM1More
Flufenamic-acidhsa04750Inflammatory mediator regulation of TRP channels4.00E-024P19174, P42338, P24723, P0DP23PLCG1, PIK3CB, PRKCH, CALM1More
Flufenamic-acidhsa04810Regulation of actin cytoskeleton2.61E-026P12814, Q13009, P42338, P11215, Q14344, Q9NRA1ACTN1, TIAM1, PIK3CB, ITGAM, GNA13, PDGFCMore
Flufenamic-acidhsa04914Progesterone-mediated oocyte maturation3.00E-048Q17RY0, P42338, Q13370, Q9Y6D9, P30304, P08238, P51812, Q02750CPEB4, PIK3CB, PDE3B, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1More
Flufenamic-acidhsa04915Estrogen signaling pathway2.96E-025P14780, P22694, P18848, Q14643, P10415MMP9, PRKACB, ATF4, ITPR1, BCL2More
Flufenamic-acidhsa04918Thyroid hormone synthesis3.50E-023P22694, P18848, Q14643PRKACB, ATF4, ITPR1More
Flufenamic-acidhsa04920Adipocytokine signaling pathway4.31E-022Q9Y478, Q96RR4PRKAB1, CAMKK2More
Flufenamic-acidhsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Flufenamic-acidhsa04924Renin secretion8.19E-045P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Flufenamic-acidhsa04926Relaxin signaling pathway8.74E-036P25963, P42338, P62873, P63218, P50151, P49767NFKBIA, PIK3CB, GNB1, GNG5, GNG10, VEGFCMore
Flufenamic-acidhsa04927Cortisol synthesis and secretion8.60E-033Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Flufenamic-acidhsa04928Parathyroid hormone synthesis, secretion and action2.33E-035Q14643, P22694, P23771, P18848, P10415ITPR1, PRKACB, GATA3, ATF4, BCL2More
Flufenamic-acidhsa04932Non-alcoholic fatty liver disease9.70E-034P18848, P01584, P13073, O15239ATF4, IL1B, COX4I1, NDUFA1More
Flufenamic-acidhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Flufenamic-acidhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Flufenamic-acidhsa05012Parkinson disease7.03E-0311O15239, P13073, P05141, P21796, P60604, P18848, P19174, P0DP23, Q13557, Q71U36, Q13509NDUFA1, COX4I1, SLC25A5, VDAC1, UBE2G2, ATF4, PLCG1, CALM1, CAMK2D, TUBA1A, TUBB3More
Flufenamic-acidhsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Flufenamic-acidhsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Flufenamic-acidhsa05020Prion disease3.37E-037P13591, P01584, P11142, O15239, P13073, P18848, P05141NCAM1, IL1B, HSPA8, NDUFA1, COX4I1, ATF4, SLC25A5More
Flufenamic-acidhsa05022Pathways of neurodegeneration - multiple diseases3.80E-026O15239, P13073, P18848, P05141, P01584, Q13557NDUFA1, COX4I1, ATF4, SLC25A5, IL1B, CAMK2DMore
Flufenamic-acidhsa05032Morphine addiction7.60E-035P62873, P63218, P50151, Q13370, P43250GNB1, GNG5, GNG10, PDE3B, GRK6More
Flufenamic-acidhsa05034Alcoholism9.92E-0510Q13547, P0DP23, P62873, P63218, P50151, Q93077, P62807, Q93079, O60814, P68431HDAC1, CALM1, GNB1, GNG5, GNG10, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Flufenamic-acidhsa05120Epithelial cell signaling in Helicobacter pylori infection3.09E-036Q16539, Q99437, P10145, P25024, P25025, P07948MAPK14, ATP6V0B, IL8, CXCR1, CXCR2, LYNMore
Flufenamic-acidhsa05132Salmonella infection2.36E-028P25963, P08238, P01106, P42338, O75369, Q71U36, Q13509, P49754NFKBIA, HSP90AB1, MYC, PIK3CB, FLNB, TUBA1A, TUBB3, VPS41More
Flufenamic-acidhsa05133Pertussis2.70E-032P10145, P0C0L4IL8, C4AMore
Flufenamic-acidhsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Flufenamic-acidhsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Flufenamic-acidhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Flufenamic-acidhsa05144Malaria2.24E-036P60033, P69905, P68871, P01375, P35443, P26718CD81, HBA2, HBB, TNF, THBS4, KLRK1More
Flufenamic-acidhsa05150Staphylococcus aureus infection4.02E-036P21462, O75015, Q14532, P59665, P59666, P12838FPR1, FCGR3B, KRT32, DEFA1; DEFA1B, DEFA3, DEFA4More
Flufenamic-acidhsa05162Measles1.56E-039P01568, P25963, P42224, P14784, P07766, P42338, P11142, P01584, Q9NP90IFNA21, NFKBIA, STAT1, IL2RB, CD3E, PIK3CB, HSPA8, IL1B, RAB9BMore
Flufenamic-acidhsa05163Human cytomegalovirus infection3.59E-0616P42338, P01375, P25963, P62873, P63218, P50151, P0DP23, Q14344, P49841, P01106, P14778, P25025, Q16539, O00463, P30101, P01568PIK3CB, TNF, NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, GSK3B, MYC, IL1R1, CXCR2, MAPK14, TRAF5, PDIA3, IFNA21More
Flufenamic-acidhsa05167Kaposi sarcoma-associated herpesvirus infection7.49E-0511P01568, P42224, P25963, P42338, P62873, P63218, P50151, P19174, P07948, P01106, P0DP23IFNA21, STAT1, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, PLCG1, LYN, MYC, CALM1More
Flufenamic-acidhsa05168Herpes simplex virus 1 infection2.16E-0312P25963, P01568, P42224, Q07955, Q01130, Q13243, P30101, P42338, Q13398, Q03923, O75820, Q9UDV6NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, PDIA3, PIK3CB, ZNF211, ZNF85, ZNF189, ZNF212More
Flufenamic-acidhsa05169Epstein-Barr virus infection1.08E-0311P01106, Q13547, P25963, P42338, P07948, P30101, Q13761, O75293, P42224, P01568, P07766MYC, HDAC1, NFKBIA, PIK3CB, LYN, PDIA3, RUNX3, GADD45B, STAT1, IFNA21, CD3EMore
Flufenamic-acidhsa05170Human immunodeficiency virus 1 infection3.24E-0310P42338, P62873, P63218, P50151, P0DP23, P30101, P01568, P25963, P19174, P07766PIK3CB, GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21, NFKBIA, PLCG1, CD3EMore
Flufenamic-acidhsa05171Coronavirus disease - COVID-199.72E-037P01584, P62753, P25398, P36578, P32969, P18077, P62829IL1B, RPS6, RPS12, RPL4, RPL9, RPL35A, RPL23More
Flufenamic-acidhsa05200Pathways in cancer2.72E-0419P42338, P08238, P42224, P25963, P19174, P01106, P43246, Q13547, P14923, P49767, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784, P40189PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, MSH2, HDAC1, JUP, VEGFC, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Flufenamic-acidhsa05202Transcriptional misregulation in cancer1.63E-0312Q12778, Q15532, Q13315, P14780, Q15744, Q16548, O15550, P05164, P12838, P08246, Q9C0K0, P24522FOXO1, SS18, ATM, MMP9, CEBPE, BCL2A1, UTX, MPO, DEFA4, ELA2, BCL11B, GADD45AMore
Flufenamic-acidhsa05203Viral carcinogenesis6.26E-0513Q12933, P42229, P42338, P06746, P07948, P29083, Q13547, Q15283, P12814, P25963, P62807, Q93079, O60814TRAF2, STAT5A, PIK3CB, POLB, LYN, GTF2E1, HDAC1, RASA2, ACTN1, NFKBIA, HIST1H2BC, H2BC9, H2BC12More
Flufenamic-acidhsa05204Chemical carcinogenesis1.77E-044Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
Flufenamic-acidhsa05206MicroRNAs in cancer2.79E-027P30304, P09493, P01106, P42338, Q13547, P20827, P19174CDC25A, TPM1, MYC, PIK3CB, HDAC1, EFNA1, PLCG1More
Flufenamic-acidhsa05212Pancreatic cancer1.72E-023P42338, P42224, O75293PIK3CB, STAT1, GADD45BMore
Flufenamic-acidhsa05214Glioma5.98E-044P0DP23, P42338, P19174, O75293CALM1, PIK3CB, PLCG1, GADD45BMore
Flufenamic-acidhsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Flufenamic-acidhsa05218Melanoma2.31E-023Q9NRA1, P42338, O75293PDGFC, PIK3CB, GADD45BMore
Flufenamic-acidhsa05220Chronic myeloid leukemia2.17E-025Q13547, P01106, P25963, P42338, O75293HDAC1, MYC, NFKBIA, PIK3CB, GADD45BMore
Flufenamic-acidhsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
Flufenamic-acidhsa05231Choline metabolism in cancer2.92E-035P42338, Q9NRA1, Q9Y259, P19174, P23743PIK3CB, PDGFC, CHKB, PLCG1, DGKAMore
Flufenamic-acidhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.32E-0413P25963, P42338, P19174, P07766, P20963, P09693, P06239, P42224, O60603, P10747, Q04759, Q9HC35, P01730NFKBIA, PIK3CB, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, CD28, PRKCQ, EML4, CD4More
Flufenamic-acidhsa05321Inflammatory bowel disease8.69E-056O60603, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Flufenamic-acidhsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Flufenamic-acidhsa05323Rheumatoid arthritis1.60E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Flufenamic-acidhsa05332Graft-versus-host disease6.43E-054P13765, P10747, P26715, Q13241HLA-DOB, CD28, KLRC1, KLRD1More
Flufenamic-acidhsa05340Primary immunodeficiency1.28E-034P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore
Flufenamic-acidhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Flufenamic-acidhsa05415Diabetic cardiomyopathy2.87E-024P05141, O15239, P13073, Q13557SLC25A5, NDUFA1, COX4I1, CAMK2DMore
Flufenamic-acidhsa05418Fluid shear stress and atherosclerosis2.38E-0511Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Flufenamic-acid (SDC: 5.40)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
AKR1C3P42330IC5050
AKR1C3P42330IC5051
AKR1C3P42330IC50410
AKR1C3P42330Ki140
AKR1C3P42330Ki3100