PharmaCoNets of Fenoterol (SPCN: 35.60 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Fenoterolhsa00030Pentose phosphate pathway3.13E-065P60891, P51854, P52209, P11413, P37837PRPS1, TKTL1, PGD, G6PD, TALDO1More
Fenoterolhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Fenoterolhsa00480Glutathione metabolism1.35E-021P11413G6PDMore
Fenoterolhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Fenoterolhsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Fenoterolhsa01200Carbon metabolism2.23E-024P51854, P11413, P37837, P60891TKTL1, G6PD, TALDO1, PRPS1More
Fenoterolhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Fenoterolhsa01523Antifolate resistance1.68E-022Q92820, P04818GGH, TYMSMore
Fenoterolhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Fenoterolhsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Fenoterolhsa04071Sphingolipid signaling pathway8.10E-047P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Fenoterolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Fenoterolhsa04110Cell cycle6.63E-046P06493, O60566, P30304, P33981, P42773, P01106CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYCMore
Fenoterolhsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Fenoterolhsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Fenoterolhsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Fenoterolhsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Fenoterolhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Fenoterolhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Fenoterolhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Fenoterolhsa04613Neutrophil extracellular trap formation2.13E-0418P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, P58876, Q16778, O60814, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, H2BC5, HIST2H2BE, H2BC12, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Fenoterolhsa04640Hematopoietic cell lineage4.95E-023P01730, P06127, P09564CD4, CD5, CD7More
Fenoterolhsa04650Natural killer cell mediated cytotoxicity5.05E-047P01375, P20963, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Fenoterolhsa04657IL-17 signaling pathway4.27E-037O00463, Q16539, P19875, P14780, Q9UJX4, P80188, P01375TRAF5, MAPK14, CXCL2, MMP9, ANAPC5, LCN2, TNFMore
Fenoterolhsa04664Fc epsilon RI signaling pathway2.18E-022P09917, P20292ALOX5, ALOX5APMore
Fenoterolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Fenoterolhsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Fenoterolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Fenoterolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Fenoterolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Fenoterolhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Fenoterolhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Fenoterolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Fenoterolhsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Fenoterolhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Fenoterolhsa04962Vasopressin-regulated water reabsorption2.18E-022P52566, P62491ARHGDIB, RAB11AMore
Fenoterolhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Fenoterolhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Fenoterolhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Fenoterolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Fenoterolhsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Fenoterolhsa05133Pertussis4.20E-021P0C0L4C4AMore
Fenoterolhsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Fenoterolhsa05144Malaria1.44E-035P69905, P68871, P01375, P35443, P26718HBA2, HBB, TNF, THBS4, KLRK1More
Fenoterolhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Fenoterolhsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Fenoterolhsa05202Transcriptional misregulation in cancer1.62E-0315Q15532, P41732, P14780, P27930, P14923, Q16548, P11215, Q13077, O15550, P35226, P05164, P08246, Q13547, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, ITGAM, TRAF1, UTX, BMI1, MPO, ELA2, HDAC1, LYL1, GADD45AMore
Fenoterolhsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Fenoterolhsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Fenoterolhsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
Fenoterolhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Fenoterolhsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Fenoterolhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Fenoterolhsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Fenoterolhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Fenoterolhsa05415Diabetic cardiomyopathy3.59E-021P11413G6PDMore

Community members of Fenoterol (SDC: 4.78)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P07550ADRB2BetaNone2 adrenergic receptorReported00.007110.22052.224
P52209PGD6Nonephosphogluconate dehydrogenase, decarboxylatingPredicted00.1950.14540.26420.6525
P11413G6PDGlucoseNone6Nonephosphate 1NonedehydrogenasePredicted10.44350.63690.29291.7884
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
ADRB2P07550Ki719
ADRB2P07550Kd100