PharmaCoNets of Felodipine (SPCN: 37.07 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Felodipinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Felodipinehsa00230Purine metabolism4.60E-024Q13370, P36959, Q13956, P27707PDE3B, GMPR, PDE6H, DCKMore
Felodipinehsa00240Pyrimidine metabolism4.50E-022P32320, P27707CDA, DCKMore
Felodipinehsa00500Starch and sucrose metabolism2.55E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Felodipinehsa00534Glycosaminoglycan biosynthesis - heparan sulfate / heparin4.77E-021Q7LGA3HS2ST1More
Felodipinehsa00604Glycosphingolipid biosynthesis - ganglio series1.34E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Felodipinehsa00670One carbon pool by folate3.99E-022O95954, Q99707FTCD, MTRMore
Felodipinehsa00730Thiamine metabolism8.06E-042P05186, P24666ALPL, ACP1More
Felodipinehsa00920Sulfur metabolism3.01E-021O95571ETHE1More
Felodipinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Felodipinehsa01100Metabolic pathways3.95E-0223Q9Y234, Q99707, P29218, P11310, P27707, Q13370, P36959, Q13956, P30043, Q02252, O60701, O14772, O95954, Q02318, P04406, O15466, P09960, Q9P2R7, Q9UHY7, P35573, Q13488, Q16718, Q02809LIPT1, MTR, IMPA1, ACADM, DCK, PDE3B, GMPR, PDE6H, BLVRB, ALDH6A1, UGDH, FPGT, FTCD, CYP27A1, GAPDH, ST8SIA5, LTA4H, SUCLA2, ENOPH1, AGL, TCIRG1, NDUFA5, PLOD1More
Felodipinehsa01524Platinum drug resistance4.45E-024P10415, Q13489, P78417, P43246BCL2, BIRC3, GSTO1, MSH2More
Felodipinehsa02010ABC transporters4.89E-021Q99758ABCA3More
Felodipinehsa03013RNA transport4.79E-022P62826, P63279RAN, UBE2IMore
Felodipinehsa03015mRNA surveillance pathway3.62E-023O43148, P61326, P52298RNMT, MAGOH, NCBP2More
Felodipinehsa03040Spliceosome1.11E-0718Q14562, O43143, O60508, P17844, O14776, P08579, O75940, P52298, P09651, Q15365, O75494, Q07955, Q01130, Q13243, P11142, O95777, O43447, P61326DHX8, DHX15, CDC40, DDX5, TCERG1, SNRPB2, SMNDC1, NCBP2, HNRNPA1, PCBP1, FUSIP1, SFRS1, SFRS2, SFRS5, HSPA8, LSM8, PPIH, MAGOHMore
Felodipinehsa03050Proteasome5.53E-032P43686, P28070PSMC4, PSMB4More
Felodipinehsa03320PPAR signaling pathway2.18E-022O00767, Q02318SCD, CYP27A1More
Felodipinehsa03460Fanconi anemia pathway3.70E-033Q9NPI8, O60673, Q9UNA4FANCF, REV3L, POLIMore
Felodipinehsa04014Ras signaling pathway2.65E-039P31751, P20827, P49767, Q13009, P17252, Q15311, P0DP23, P62873, P19174AKT2, EFNA1, VEGFC, TIAM1, PRKCA, RALBP1, CALM1, GNB1, PLCG1More
Felodipinehsa04015Rap1 signaling pathway5.41E-039P20827, P49767, Q13009, Q08828, P51828, P31751, P0DP23, P17252, P19174EFNA1, VEGFC, TIAM1, ADCY1, ADCY7, AKT2, CALM1, PRKCA, PLCG1More
Felodipinehsa04020Calcium signaling pathway1.04E-0611P27987, Q08828, Q13557, P17252, O15399, P19174, P61073, P0DP23, P51828, P23634, P49767ITPKB, ADCY1, CAMK2D, PRKCA, GRIN2D, PLCG1, CXCR4, CALM1, ADCY7, ATP2B4, VEGFCMore
Felodipinehsa04024cAMP signaling pathway3.01E-039Q08828, P51828, P31751, P0DP23, P23634, Q13557, Q13370, O15399, Q13009ADCY1, ADCY7, AKT2, CALM1, ATP2B4, CAMK2D, PDE3B, GRIN2D, TIAM1More
Felodipinehsa04062Chemokine signaling pathway2.04E-0210P51684, Q8NHW4, P19174, P62873, Q08828, P51828, Q13009, P14598, P42224, P31751CCR6, CCL4L2, PLCG1, GNB1, ADCY1, ADCY7, TIAM1, NCF1, STAT1, AKT2More
Felodipinehsa04064NF-kappa B signaling pathway1.98E-0620P10415, Q13489, P51617, O00463, Q13546, P01584, P01375, P29965, P19174, Q04759, Q9UDY8, Q13077, Q16548, Q8WV28, P24522, O75293, Q8NHW4, P09341, Q9UNE0, Q9NQC7BCL2, BIRC3, IRAK1, TRAF5, RIPK1, IL1B, TNF, CD40LG, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, BLNK, GADD45A, GADD45B, CCL4L2, CXCL1, EDAR, CYLDMore
Felodipinehsa04070Phosphatidylinositol signaling system5.66E-046P19174, P0DP23, P23743, P48426, P27987, P17252PLCG1, CALM1, DGKA, PIP4K2A, ITPKB, PRKCAMore
Felodipinehsa04071Sphingolipid signaling pathway1.89E-0410P17252, Q9H228, P01375, Q13510, Q13362, Q9BX95, Q16539, P10415, Q9UQC2, P01042PRKCA, EDG8, TNF, ASAH1, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2, KNG1More
Felodipinehsa04072Phospholipase D signaling pathway2.03E-028P31751, P19174, P17252, Q15438, Q08828, P51828, P23743, P00734AKT2, PLCG1, PRKCA, PSCD1, ADCY1, ADCY7, DGKA, F2More
Felodipinehsa04080Neuroactive ligand-receptor interaction2.54E-027P08311, Q15722, Q9H228, P21462, P21730, Q16581, P35318CTSG, LTB4R, EDG8, FPR1, C5AR1, C3AR1, ADMMore
Felodipinehsa04140Autophagy - animal2.58E-027P31751, Q7L523, Q96RR4, O75460, P10415, Q96GC9, Q8TEV9AKT2, RRAGA, CAMKK2, ERN1, BCL2, TMEM49, SMCR8More
Felodipinehsa04144Endocytosis8.99E-0312P11142, Q9H444, O43633, O75351, Q9NZZ3, Q15438, Q14161, P14784, Q96QK1, Q9UMY4, Q9Y5X3, Q9UNH7HSPA8, CHMP4B, CHMP2A, VPS4B, CHMP5, PSCD1, GIT2, IL2RB, VPS35, SNX12, SNX5, SNX6More
Felodipinehsa04145Phagosome5.56E-038P60709, P63261, Q15075, Q15080, P14598, Q13509, Q13488, O60603ACTB, ACTG1, EEA1, NCF4, NCF1, TUBB3, TCIRG1, TLR2More
Felodipinehsa04151PI3K-Akt signaling pathway4.68E-0318O43521, P27348, P20827, P49767, Q13362, P08238, P62873, P16144, P48551, P14784, P23458, P01568, P15336, P18848, P10415, P17252, Q16513, Q6ZUJ8BCL2L11, YWHAQ, EFNA1, VEGFC, PPP2R5C, HSP90AB1, GNB1, ITGB4, IFNAR2, IL2RB, JAK1, IFNA21, ATF2, ATF4, BCL2, PRKCA, PKN2, PIK3AP1More
Felodipinehsa04210Apoptosis7.52E-047O76075, P07384, P01375, Q9NR28, Q16548, P60709, P63261DFFB, CAPN1, TNF, DIABLO, BCL2A1, ACTB, ACTG1More
Felodipinehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Felodipinehsa04217Necroptosis4.04E-0916P01568, P23458, Q13489, Q9NQC7, Q13546, P42224, P08238, P01584, P0C0S5, Q6FI13, P10415, Q13557, Q9H444, O43633, Q9NZZ3, O75351IFNA21, JAK1, BIRC3, CYLD, RIPK1, STAT1, HSP90AB1, IL1B, H2AFZ, H2AC18; H2AC19, BCL2, CAMK2D, CHMP4B, CHMP2A, CHMP5, VPS4BMore
Felodipinehsa04261Adrenergic signaling in cardiomyocytes4.43E-0611P09493, Q08828, P51828, P31751, P18848, Q13362, P0DP23, Q13557, P17252, P10415, P23634TPM1, ADCY1, ADCY7, AKT2, ATF4, PPP2R5C, CALM1, CAMK2D, PRKCA, BCL2, ATP2B4More
Felodipinehsa04340Hedgehog signaling pathway1.76E-034P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Felodipinehsa04360Axon guidance8.44E-048P61073, P16333, P20827, O95631, P17252, Q13557, P23528, P19174CXCR4, NCK1, EFNA1, NTN1, PRKCA, CAMK2D, CFL1, PLCG1More
Felodipinehsa04371Apelin signaling pathway3.08E-027P62873, P31751, Q08828, P51828, Q13370, Q13485, P0DP23GNB1, AKT2, ADCY1, ADCY7, PDE3B, SMAD4, CALM1More
Felodipinehsa04380Osteoclast differentiation4.18E-027Q9NQC7, Q9UQC2, P23458, P42224, P01584, Q15080, P14598CYLD, GAB2, JAK1, STAT1, IL1B, NCF4, NCF1More
Felodipinehsa04390Hippo signaling pathway2.80E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa04510Focal adhesion3.76E-027P16144, O75369, Q15942, P17252, Q13489, P10415, P49767ITGB4, FLNB, ZYX, PRKCA, BIRC3, BCL2, VEGFCMore
Felodipinehsa04520Adherens junction1.58E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa04530Tight junction3.88E-033P60709, P63261, P60660ACTB, ACTG1, MYL6More
Felodipinehsa04540Gap junction4.08E-025P17252, Q13509, P68371, Q08828, P51828PRKCA, TUBB3, TUBB2C, ADCY1, ADCY7More
Felodipinehsa04610Complement and coagulation cascades4.69E-031P0C0L4C4AMore
Felodipinehsa04611Platelet activation2.61E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa04613Neutrophil extracellular trap formation1.37E-0212O60603, P05164, P08246, Q9UM07, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Felodipinehsa04620Toll-like receptor signaling pathway2.13E-036P51617, Q13546, P01568, P31751, P42224, Q8NHW4IRAK1, RIPK1, IFNA21, AKT2, STAT1, CCL4L2More
Felodipinehsa04621NOD-like receptor signaling pathway7.82E-0418P01584, P08238, Q16539, Q14643, P23458, P42224, P01568, Q9H3M7, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q13546, P01375, P09341, P12838IL1B, HSP90AB1, MAPK14, ITPR1, JAK1, STAT1, IFNA21, TXNIP, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RIPK1, TNF, CXCL1, DEFA4More
Felodipinehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Felodipinehsa04623Cytosolic DNA-sensing pathway7.83E-043P01568, Q13546, Q8NHW4IFNA21, RIPK1, CCL4L2More
Felodipinehsa04630JAK-STAT signaling pathway1.16E-028P31751, P10415, P42224, P23458, P14784, P16871, Q13651, P01568AKT2, BCL2, STAT1, JAK1, IL2RB, IL7R, IL10RA, IFNA21More
Felodipinehsa04640Hematopoietic cell lineage2.82E-034P08514, P21926, P07766, P09564ITGA2B, CD9, CD3E, CD7More
Felodipinehsa04657IL-17 signaling pathway2.01E-037O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Felodipinehsa04658Th1 and Th2 cell differentiation3.21E-039Q04759, P20963, P09693, Q16539, Q14765, P42226, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, MAPK14, STAT4, STAT6, GATA3, TBX21, HLA-DOBMore
Felodipinehsa04659Th17 cell differentiation3.18E-028Q04759, Q16539, P42226, P13765, Q9UL17, P23771, P09693, P20963PRKCQ, MAPK14, STAT6, HLA-DOB, TBX21, GATA3, CD3G, CD247More
Felodipinehsa04660T cell receptor signaling pathway1.07E-029P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q16539, P49841TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, MAPK14, GSK3BMore
Felodipinehsa04662B cell receptor signaling pathway3.68E-022P25963, P20023NFKBIA, CR2More
Felodipinehsa04666Fc gamma R-mediated phagocytosis2.78E-026P08575, P19174, P23528, Q9UQC2, P14598, P17252PTPRC, PLCG1, CFL1, GAB2, NCF1, PRKCAMore
Felodipinehsa04670Leukocyte transendothelial migration4.07E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa04713Circadian entrainment5.61E-057O15399, P0DP23, Q13557, P17252, P62873, Q08828, P51828GRIN2D, CALM1, CAMK2D, PRKCA, GNB1, ADCY1, ADCY7More
Felodipinehsa04714Thermogenesis3.64E-044P15336, P60709, P63261, P36542ATF2, ACTB, ACTG1, ATP5C1More
Felodipinehsa04720Long-term potentiation3.26E-036P17252, Q13557, P0DP23, P18848, O15399, Q08828PRKCA, CAMK2D, CALM1, ATF4, GRIN2D, ADCY1More
Felodipinehsa04724Glutamatergic synapse5.91E-037P48058, O15399, Q08828, P51828, P17252, P62873, P15104GRIA4, GRIN2D, ADCY1, ADCY7, PRKCA, GNB1, GLULMore
Felodipinehsa04725Cholinergic synapse4.42E-048Q08828, P51828, P17252, P62873, P18848, Q13557, P31751, P10415ADCY1, ADCY7, PRKCA, GNB1, ATF4, CAMK2D, AKT2, BCL2More
Felodipinehsa04727GABAergic synapse4.08E-025Q08828, P51828, P62873, P46459, P17252ADCY1, ADCY7, GNB1, NSF, PRKCAMore
Felodipinehsa04740Olfactory transduction2.61E-023P62873, Q13557, P0DP23GNB1, CAMK2D, CALM1More
Felodipinehsa04744Phototransduction1.30E-052P62873, P0DP23GNB1, CALM1More
Felodipinehsa04750Inflammatory mediator regulation of TRP channels4.32E-058P01584, Q08828, P51828, Q13557, P19174, P17252, P0DP23, P01042IL1B, ADCY1, ADCY7, CAMK2D, PLCG1, PRKCA, CALM1, KNG1More
Felodipinehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Felodipinehsa04911Insulin secretion3.47E-024Q08828, P17252, P18848, Q13557ADCY1, PRKCA, ATF4, CAMK2DMore
Felodipinehsa04912GnRH signaling pathway2.85E-025P17252, Q08828, P18848, Q13557, P0DP23PRKCA, ADCY1, ATF4, CAMK2D, CALM1More
Felodipinehsa04914Progesterone-mediated oocyte maturation3.26E-026Q08828, P51828, P31751, Q13370, Q9UJX4, P08238ADCY1, ADCY7, AKT2, PDE3B, ANAPC5, HSP90AB1More
Felodipinehsa04915Estrogen signaling pathway3.28E-039P18848, Q08828, P51828, P31751, P08238, P11142, P0DP23, Q15788, P10415ATF4, ADCY1, ADCY7, AKT2, HSP90AB1, HSPA8, CALM1, NCOA1, BCL2More
Felodipinehsa04919Thyroid hormone signaling pathway5.60E-046P49841, P22694, P60709, P63261, O60244, Q9NVC6GSK3B, PRKACB, ACTB, ACTG1, MED14, MED17More
Felodipinehsa04921Oxytocin signaling pathway1.77E-033P60660, P60709, P63261MYL6, ACTB, ACTG1More
Felodipinehsa04923Regulation of lipolysis in adipocytes2.12E-024Q08828, P51828, Q13370, P31751ADCY1, ADCY7, PDE3B, AKT2More
Felodipinehsa04925Aldosterone synthesis and secretion6.45E-047P18848, Q08828, P51828, P0DP23, P17252, Q13557, P23634ATF4, ADCY1, ADCY7, CALM1, PRKCA, CAMK2D, ATP2B4More
Felodipinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Felodipinehsa04933AGE-RAGE signaling pathway in diabetic complications2.04E-068Q13485, P01584, P42224, P10415, P31751, P49767, P17252, P19174SMAD4, IL1B, STAT1, BCL2, AKT2, VEGFC, PRKCA, PLCG1More
Felodipinehsa04935Growth hormone synthesis, secretion and action3.93E-026P19174, Q08828, P51828, P17252, P31751, P42224PLCG1, ADCY1, ADCY7, PRKCA, AKT2, STAT1More
Felodipinehsa04970Salivary secretion1.35E-035Q08828, P51828, P23634, P17252, P0DP23ADCY1, ADCY7, ATP2B4, PRKCA, CALM1More
Felodipinehsa04971Gastric acid secretion1.02E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa04972Pancreatic secretion1.92E-035P23634, P17252, Q08828, P51828, P62491ATP2B4, PRKCA, ADCY1, ADCY7, RAB11AMore
Felodipinehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Felodipinehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Felodipinehsa05014Amyotrophic lateral sclerosis2.98E-023P36542, P60709, P63261ATP5C1, ACTB, ACTG1More
Felodipinehsa05017Spinocerebellar ataxia3.80E-038P17252, O75460, Q8TB72, O15399, P31751, P28070, P43686, O00232PRKCA, ERN1, PUM2, GRIN2D, AKT2, PSMB4, PSMC4, PSMD12More
Felodipinehsa05031Amphetamine addiction2.85E-025O15399, P0DP23, Q13557, P18848, P17252GRIN2D, CALM1, CAMK2D, ATF4, PRKCAMore
Felodipinehsa05032Morphine addiction4.08E-025Q08828, P51828, P62873, Q13370, P17252ADCY1, ADCY7, GNB1, PDE3B, PRKCAMore
Felodipinehsa05100Bacterial invasion of epithelial cells1.02E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa05110Vibrio cholerae infection3.95E-032P60709, P63261ACTB, ACTG1More
Felodipinehsa05131Shigellosis1.91E-023P60709, P63261, P07384ACTB, ACTG1, CAPN1More
Felodipinehsa05132Salmonella infection2.31E-0515P51617, P01584, P08238, Q96RF0, Q13546, Q13489, P10415, P08575, O75369, Q13561, O60282, Q13509, P68371, P49754, Q9NP90IRAK1, IL1B, HSP90AB1, SNAG1, RIPK1, BIRC3, BCL2, PTPRC, FLNB, DCTN2, KIF5C, TUBB3, TUBB2C, VPS41, RAB9BMore
Felodipinehsa05133Pertussis3.94E-045P0DP23, P01584, P23528, P09871, P51617CALM1, IL1B, CFL1, C1S, IRAK1More
Felodipinehsa05135Yersinia infection3.88E-033P60709, P63261, Q16513ACTB, ACTG1, PKN2More
Felodipinehsa05140Leishmaniasis2.58E-025P14598, O60603, P25963, P29350, Q15080NCF1, TLR2, NFKBIA, PTPN6, NCF4More
Felodipinehsa05143African trypanosomiasis3.87E-023P01584, P17252, P01042IL1B, PRKCA, KNG1More
Felodipinehsa05145Toxoplasmosis5.28E-059P51617, P10415, Q13489, P23458, P42224, P31751, P11142, P29965, Q13651IRAK1, BCL2, BIRC3, JAK1, STAT1, AKT2, HSPA8, CD40LG, IL10RAMore
Felodipinehsa05150Staphylococcus aureus infection8.05E-038P0C0L4, P21730, P21462, O75015, P13765, Q16581, P13646, P12838C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, KRT13, DEFA4More
Felodipinehsa05161Hepatitis B1.31E-0410P17252, P18848, P23458, Q13485, P31751, P10415, P27348, P01568, P42224, P51617PRKCA, ATF4, JAK1, SMAD4, AKT2, BCL2, YWHAQ, IFNA21, STAT1, IRAK1More
Felodipinehsa05162Measles1.74E-0410P51617, P01568, P23458, P42224, P14784, P31751, P11142, P01584, Q9NP90, P10415IRAK1, IFNA21, JAK1, STAT1, IL2RB, AKT2, HSPA8, IL1B, RAB9B, BCL2More
Felodipinehsa05163Human cytomegalovirus infection2.59E-0314P31751, P62873, P0DP23, Q8NHW4, Q08828, P51828, P23458, P01584, P61073, P17252, Q13651, P18848, P61769, P01568AKT2, GNB1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, IL1B, CXCR4, PRKCA, IL10RA, ATF4, B2M, IFNA21More
Felodipinehsa05164Influenza A7.10E-033P48551, P60709, P63261IFNAR2, ACTB, ACTG1More
Felodipinehsa05168Herpes simplex virus 1 infection2.45E-0518P01568, P01584, Q9UBU9, P23458, P42224, Q07955, Q01130, Q13243, Q13489, P51617, P61769, P31751, Q13398, Q6P280, Q03923, Q9UDV6, P10415, Q14232IFNA21, IL1B, NXF1, JAK1, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, IRAK1, B2M, AKT2, ZNF211, ZNF529, ZNF85, ZNF212, BCL2, EIF2B1More
Felodipinehsa05169Epstein-Barr virus infection4.32E-0211P13765, O00463, P16070, P10415, Q16539, P24522, Q8WV28, P01375, O60603, P09693, P20963HLA-DOB, TRAF5, CD44, BCL2, MAPK14, GADD45A, BLNK, TNF, TLR2, CD3G, CD247More
Felodipinehsa05170Human immunodeficiency virus 1 infection4.12E-0512P31751, P62873, P0DP23, P61073, P17252, P61769, P01568, P51617, P19174, P23528, P10415, Q9Y6Q5AKT2, GNB1, CALM1, CXCR4, PRKCA, B2M, IFNA21, IRAK1, PLCG1, CFL1, BCL2, AP1M2More
Felodipinehsa05200Pathways in cancer4.30E-0928P23458, P08238, P42224, P19174, Q15311, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P31751, Q08828, P51828, P62873, P61073, P78417, O75293, Q15788, P0DP23, Q13557, O43521, P01568, P14784, P16871, P00734, P01042JAK1, HSP90AB1, STAT1, PLCG1, RALBP1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, AKT2, ADCY1, ADCY7, GNB1, CXCR4, GSTO1, GADD45B, NCOA1, CALM1, CAMK2D, BCL2L11, IFNA21, IL2RB, IL7R, F2, KNG1More
Felodipinehsa05202Transcriptional misregulation in cancer8.07E-0414Q15532, P14780, P27930, Q16548, Q13077, Q15652, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P24522SS18, MMP9, IL1R2, BCL2A1, TRAF1, JMJD1C, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, GADD45AMore
Felodipinehsa05204Chemical carcinogenesis3.70E-033P00325, P78417, P33260ADH1B, GSTO1, CYP2C18More
Felodipinehsa05206MicroRNAs in cancer4.07E-022P15311, P63279VIL2, UBE2IMore
Felodipinehsa05212Pancreatic cancer5.55E-036P31751, Q15311, P23458, P42224, Q13485, O75293AKT2, RALBP1, JAK1, STAT1, SMAD4, GADD45BMore
Felodipinehsa05214Glioma2.38E-068P09619, P0DP23, Q13557, P17252, Q02750, P31751, P19174, O75293PDGFRB, CALM1, CAMK2D, PRKCA, MAP2K1, AKT2, PLCG1, GADD45BMore
Felodipinehsa05217Basal cell carcinoma1.43E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Felodipinehsa05218Melanoma1.34E-022P09619, Q02750PDGFRB, MAP2K1More
Felodipinehsa05225Hepatocellular carcinoma4.07E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa05230Central carbon metabolism in cancer4.10E-022P09619, Q02750PDGFRB, MAP2K1More
Felodipinehsa05321Inflammatory bowel disease7.62E-047O60603, P01375, P13765, Q14765, Q9UL17, P42226, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, STAT6, GATA3More
Felodipinehsa05340Primary immunodeficiency2.68E-022P11912, P07766CD79A, CD3EMore
Felodipinehsa05410Hypertrophic cardiomyopathy1.02E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa05412Arrhythmogenic right ventricular cardiomyopathy8.96E-032P60709, P63261ACTB, ACTG1More
Felodipinehsa05414Dilated cardiomyopathy1.73E-022P60709, P63261ACTB, ACTG1More
Felodipinehsa05416Viral myocarditis8.96E-032P60709, P63261ACTB, ACTG1More
Felodipinehsa05418Fluid shear stress and atherosclerosis3.64E-038P14598, P78417, P60709, P63261, P10415, P0DP23, P08238, Q92974NCF1, GSTO1, ACTB, ACTG1, BCL2, CALM1, HSP90AB1, ARHGEF2More

Community members of Felodipine (SDC: 2.28)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P0DP23CALM1CalmodulinNone1Reported00.45520.147911.5235
P08235NR3C2Mineralocorticoid receptorReported10.185510.01372.1064
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P06737PYGLGlycogen phosphorylase, liver formPredicted00.37330.22110.31690.9457
P54284CACNB3VoltageNonedependent LNonetype calcium channel subunit betaNone3Predicted00.10260.15390.32910.6881
P0DP25CALM3CalmodulinNone3Predicted00.56610.147900.5789
P0DP24CALM2CalmodulinNone2Predicted00.43760.147900.5147
P60660MYL6Myosin light polypeptide 6Predicted00.55950.06870.21750.6346
P24844MYL9Myosin regulatory light polypeptide 9Predicted00.00640.0630.60260.7318
P14649MYL6BMyosin light chain 6BPredicted00.04770.06530.21750.3719
P05976MYL1Myosin light chain 1/3, skeletal muscle isoformPredicted00.25810.061900.2528
O15182CETN3CentrinNone3Predicted00.18720.059400.2123
Q96A32MYLPFMyosin regulatory light chain 2, skeletal muscle isoformPredicted00.01350.04730.54120.6425
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)