PharmaCoNets of Eugenol (SPCN: 24.33 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Eugenolhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Eugenolhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Eugenolhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P08069IGF1RMore
Eugenolhsa01522Endocrine resistance2.16E-021P08069IGF1RMore
Eugenolhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Eugenolhsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Eugenolhsa04010MAPK signaling pathway4.15E-021P08069IGF1RMore
Eugenolhsa04014Ras signaling pathway3.65E-021P08069IGF1RMore
Eugenolhsa04015Rap1 signaling pathway2.99E-021P08069IGF1RMore
Eugenolhsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Eugenolhsa04068FoxO signaling pathway1.99E-021P08069IGF1RMore
Eugenolhsa04071Sphingolipid signaling pathway1.87E-026Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Eugenolhsa04114Oocyte meiosis2.99E-021P08069IGF1RMore
Eugenolhsa04140Autophagy - animal2.82E-021P08069IGF1RMore
Eugenolhsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Eugenolhsa04150mTOR signaling pathway2.32E-021P08069IGF1RMore
Eugenolhsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Eugenolhsa04211Longevity regulating pathway2.16E-021P08069IGF1RMore
Eugenolhsa04213Longevity regulating pathway - multiple species1.66E-021P08069IGF1RMore
Eugenolhsa04510Focal adhesion3.48E-021P08069IGF1RMore
Eugenolhsa04520Adherens junction8.29E-031P08069IGF1RMore
Eugenolhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P08069IGF1RMore
Eugenolhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Eugenolhsa04613Neutrophil extracellular trap formation7.32E-0313O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Eugenolhsa04640Hematopoietic cell lineage1.64E-032P04234, P20036CD3D, HLA-DPA1More
Eugenolhsa04657IL-17 signaling pathway4.98E-026O00463, Q16539, P14780, Q9UJX4, P80188, P01375TRAF5, MAPK14, MMP9, ANAPC5, LCN2, TNFMore
Eugenolhsa04658Th1 and Th2 cell differentiation1.85E-032P04234, P20036CD3D, HLA-DPA1More
Eugenolhsa04659Th17 cell differentiation1.64E-032P20036, P04234HLA-DPA1, CD3DMore
Eugenolhsa04672Intestinal immune network for IgA production3.16E-021P20036HLA-DPA1More
Eugenolhsa04730Long-term depression1.16E-021P08069IGF1RMore
Eugenolhsa04750Inflammatory mediator regulation of TRP channels4.93E-021Q9Y5S1TRPV2More
Eugenolhsa04913Ovarian steroidogenesis1.16E-021P08069IGF1RMore
Eugenolhsa04914Progesterone-mediated oocyte maturation2.16E-021P08069IGF1RMore
Eugenolhsa04940Type I diabetes mellitus4.05E-021P20036HLA-DPA1More
Eugenolhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Eugenolhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Eugenolhsa05133Pertussis4.20E-021P0C0L4C4AMore
Eugenolhsa05142Chagas disease4.93E-021P04234CD3DMore
Eugenolhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Eugenolhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Eugenolhsa05166Human T-cell leukemia virus 1 infection9.87E-032P04234, P20036CD3D, HLA-DPA1More
Eugenolhsa05169Epstein-Barr virus infection3.43E-032P20036, P04234HLA-DPA1, CD3DMore
Eugenolhsa05202Transcriptional misregulation in cancer8.39E-0413Q15532, P41732, P14780, P27930, P14923, Q16548, Q13077, O15550, P08069, P35226, P05164, P08246, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, TRAF1, UTX, IGF1R, BMI1, MPO, ELA2, GADD45AMore
Eugenolhsa05205Proteoglycans in cancer3.48E-021P08069IGF1RMore
Eugenolhsa05214Glioma9.95E-031P08069IGF1RMore
Eugenolhsa05215Prostate cancer1.33E-021P08069IGF1RMore
Eugenolhsa05218Melanoma6.63E-031P08069IGF1RMore
Eugenolhsa05224Breast cancer1.49E-021P08069IGF1RMore
Eugenolhsa05225Hepatocellular carcinoma1.33E-021P08069IGF1RMore
Eugenolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer4.93E-021P04234CD3DMore
Eugenolhsa05310Asthma2.71E-021P20036HLA-DPA1More
Eugenolhsa05320Autoimmune thyroid disease3.60E-021P20036HLA-DPA1More
Eugenolhsa05321Inflammatory bowel disease4.05E-021P20036HLA-DPA1More
Eugenolhsa05330Allograft rejection3.60E-021P20036HLA-DPA1More
Eugenolhsa05332Graft-versus-host disease4.05E-021P20036HLA-DPA1More
Eugenolhsa05340Primary immunodeficiency1.81E-021P04234CD3DMore
Eugenolhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Eugenolhsa05416Viral myocarditis4.49E-021P20036HLA-DPA1More

Community members of Eugenol (SDC: 3.09)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q9Y5S1TRPV2Transient receptor potential cation channel subfamily V member 2Predicted00.62910.03880.24020.6324
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)