| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Estradiol-dienanthate | hsa00071 | Fatty acid degradation | 4.66E-02 | 3 | O75521, P11766, P33121 | ECI2, ADH5, ACSL1 | More | | | Estradiol-dienanthate | hsa00220 | Arginine biosynthesis | 1.94E-03 | 3 | P15104, P05089, P49448 | GLUL, ARG1, GLUD2 | More | | | Estradiol-dienanthate | hsa00250 | Alanine, aspartate and glutamate metabolism | 4.32E-02 | 2 | P49448, P15104 | GLUD2, GLUL | More | | | Estradiol-dienanthate | hsa00340 | Histidine metabolism | 4.52E-02 | 1 | O95954 | FTCD | More | | | Estradiol-dienanthate | hsa00500 | Starch and sucrose metabolism | 3.28E-05 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Estradiol-dienanthate | hsa00520 | Amino sugar and nucleotide sugar metabolism | 7.87E-03 | 3 | Q16222, Q9Y223, P06865 | UAP1, GNE, HEXA | More | | | Estradiol-dienanthate | hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate | 6.96E-04 | 1 | Q9NY97 | B3GNT2 | More | | | Estradiol-dienanthate | hsa00564 | Glycerophospholipid metabolism | 9.70E-03 | 2 | Q9Y259, P49619 | CHKB, DGKG | More | | | Estradiol-dienanthate | hsa00591 | Linoleic acid metabolism | 3.18E-02 | 1 | P11712 | CYP2C9 | More | | | Estradiol-dienanthate | hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series | 3.78E-02 | 1 | Q9NY97 | B3GNT2 | More | | | Estradiol-dienanthate | hsa00603 | Glycosphingolipid biosynthesis - globo and isoglobo series | 4.30E-03 | 2 | P06865, O75752 | HEXA, B3GALNT1 | More | | | Estradiol-dienanthate | hsa00730 | Thiamine metabolism | 3.21E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Estradiol-dienanthate | hsa00770 | Pantothenate and CoA biosynthesis | 7.90E-03 | 3 | O95498, O95497, Q9NRN7 | VNN2, VNN1, AASDHPPT | More | | | Estradiol-dienanthate | hsa00910 | Nitrogen metabolism | 4.32E-02 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Estradiol-dienanthate | hsa00970 | Aminoacyl-tRNA biosynthesis | 1.58E-04 | 4 | O95363, P54136, P14868, Q15046 | FARS2, RARS1, DARS, KARS | More | | | Estradiol-dienanthate | hsa01100 | Metabolic pathways | 2.25E-02 | 7 | Q9Y259, Q13956, P49619, O95954, Q02318, Q9UBX8, P35573 | CHKB, PDE6H, DGKG, FTCD, CYP27A1, B4GALT6, AGL | More | | | Estradiol-dienanthate | hsa01210 | 2-Oxocarboxylic acid metabolism | 1.91E-02 | 1 | P50213 | IDH3A | More | | | Estradiol-dienanthate | hsa03013 | RNA transport | 8.19E-04 | 7 | Q15287, Q9UBU9, P35658, P63279, P55884, O15371, P20042 | RNPS1, NXF1, NUP214, UBE2I, EIF3B, EIF3D, EIF2S2 | More | | | Estradiol-dienanthate | hsa03040 | Spliceosome | 3.98E-02 | 4 | Q15427, P38159, P61978, P11142 | SF3B4, RBMX, HNRPK, HSPA8 | More | | | Estradiol-dienanthate | hsa03060 | Protein export | 1.13E-03 | 2 | P37108, Q15005 | SRP14, SPCS2 | More | | | Estradiol-dienanthate | hsa03320 | PPAR signaling pathway | 2.00E-03 | 4 | Q6PCB7, Q9UNU6, Q13133, Q02318 | SLC27A1, CYP8B1, NR1H3, CYP27A1 | More | | | Estradiol-dienanthate | hsa04012 | ErbB signaling pathway | 2.98E-03 | 6 | P21860, P16333, Q13557, P19174, O14944, P01106 | ERBB3, NCK1, CAMK2D, PLCG1, EREG, MYC | More | | | Estradiol-dienanthate | hsa04020 | Calcium signaling pathway | 6.50E-04 | 6 | Q96DU7, P45880, Q13557, P21860, P51828, P23634 | ITPKC, VDAC2, CAMK2D, ERBB3, ADCY7, ATP2B4 | More | | | Estradiol-dienanthate | hsa04022 | cGMP-PKG signaling pathway | 4.72E-02 | 4 | Q99941, P23634, P51828, P45880 | CREBL1, ATP2B4, ADCY7, VDAC2 | More | | | Estradiol-dienanthate | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 2.60E-02 | 3 | Q8NHW4, P61073, Q13651 | CCL4L2, CXCR4, IL10RA | More | | | Estradiol-dienanthate | hsa04062 | Chemokine signaling pathway | 4.38E-04 | 11 | P25024, P25025, P47992, Q9UBD3, P07948, P42338, P63218, P50151, P49407, Q08881, P49841 | CXCR1, CXCR2, XCL1, XCL2, LYN, PIK3CB, GNG5, GNG10, ARRB1, ITK, GSK3B | More | | | Estradiol-dienanthate | hsa04064 | NF-kappa B signaling pathway | 4.09E-03 | 5 | P01584, P67870, P63279, Q8NHW4, Q9NQC7 | IL1B, CSNK2B, UBE2I, CCL4L2, CYLD | More | | | Estradiol-dienanthate | hsa04110 | Cell cycle | 1.79E-03 | 8 | Q9UBD5, P06493, O75293, P30304, P33981, P42773, P01106, Q13547 | ORC3, CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYC, HDAC1 | More | | | Estradiol-dienanthate | hsa04114 | Oocyte meiosis | 4.51E-03 | 5 | Q9Y6D9, P51812, Q02750, P16298, Q17RY0 | MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4 | More | | | Estradiol-dienanthate | hsa04141 | Protein processing in endoplasmic reticulum | 3.64E-02 | 5 | Q99941, O75460, P11142, Q9H3Z4, P07900 | CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1 | More | | | Estradiol-dienanthate | hsa04150 | mTOR signaling pathway | 2.72E-02 | 4 | P42338, Q9NQL2, Q13322, P49841 | PIK3CB, RRAGD, GRB10, GSK3B | More | | | Estradiol-dienanthate | hsa04215 | Apoptosis - multiple species | 1.56E-02 | 2 | Q13489, P10415 | BIRC3, BCL2 | More | | | Estradiol-dienanthate | hsa04260 | Cardiac muscle contraction | 4.49E-02 | 3 | P67936, P13073, P12074 | TPM4, COX4I1, COX6A1 | More | | | Estradiol-dienanthate | hsa04261 | Adrenergic signaling in cardiomyocytes | 3.98E-02 | 4 | P51828, Q99941, Q13557, P23634 | ADCY7, CREBL1, CAMK2D, ATP2B4 | More | | | Estradiol-dienanthate | hsa04330 | Notch signaling pathway | 4.34E-02 | 2 | Q92542, P46531 | NCSTN, NOTCH1 | More | | | Estradiol-dienanthate | hsa04350 | TGF-beta signaling pathway | 4.88E-02 | 1 | P37173 | TGFBR2 | More | | | Estradiol-dienanthate | hsa04370 | VEGF signaling pathway | 2.47E-03 | 3 | P16298, Q05397, Q02750 | PPP3CB, PTK2, MAP2K1 | More | | | Estradiol-dienanthate | hsa04380 | Osteoclast differentiation | 4.71E-02 | 6 | Q16539, P06239, P42338, P14778, O75015, Q8N149 | MAPK14, LCK, PIK3CB, IL1R1, FCGR3B, LILRA2 | More | | | Estradiol-dienanthate | hsa04390 | Hippo signaling pathway | 2.17E-03 | 5 | P63261, P84022, Q13485, O15105, Q13489 | ACTG1, SMAD3, SMAD4, SMAD7, BIRC3 | More | | | Estradiol-dienanthate | hsa04530 | Tight junction | 4.35E-02 | 2 | P63261, Q92974 | ACTG1, ARHGEF2 | More | | | Estradiol-dienanthate | hsa04612 | Antigen processing and presentation | 1.51E-02 | 7 | P13765, P48382, P26715, P26717, Q13241, O43908, P01732 | HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A | More | | | Estradiol-dienanthate | hsa04613 | Neutrophil extracellular trap formation | 3.07E-02 | 3 | P11215, P62807, O60814 | ITGAM, HIST1H2BC, H2BC12 | More | | | Estradiol-dienanthate | hsa04614 | Renin-angiotensin system | 1.52E-02 | 1 | P50052 | AGTR2 | More | | | Estradiol-dienanthate | hsa04623 | Cytosolic DNA-sensing pathway | 1.54E-02 | 2 | P01584, Q8NHW4 | IL1B, CCL4L2 | More | | | Estradiol-dienanthate | hsa04650 | Natural killer cell mediated cytotoxicity | 3.63E-06 | 13 | P16298, P50591, P01375, P78314, P06239, O60880, P20963, Q02750, Q13241, P26718, O75015, P26717, P26715 | PPP3CB, TNFSF10, TNF, SH3BP2, LCK, SH2D1A, CD247, MAP2K1, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | | Estradiol-dienanthate | hsa04658 | Th1 and Th2 cell differentiation | 2.25E-06 | 10 | P07766, P20963, Q16539, P19174, P01730, P06239, P42224, Q9UL17, P14784, Q13761 | CD3E, CD247, MAPK14, PLCG1, CD4, LCK, STAT1, TBX21, IL2RB, RUNX3 | More | | | Estradiol-dienanthate | hsa04659 | Th17 cell differentiation | 2.20E-05 | 13 | P25963, Q16539, P19174, P01730, P06239, P42224, P14784, P14778, Q9UL17, P84022, Q13485, P07766, P20963 | NFKBIA, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, IL1R1, TBX21, SMAD3, SMAD4, CD3E, CD247 | More | | | Estradiol-dienanthate | hsa04660 | T cell receptor signaling pathway | 1.60E-05 | 15 | P01375, P42338, O95267, Q08881, P19174, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841 | TNF, PIK3CB, RASGRP1, ITK, PLCG1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3B | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P01375 | TNF | Tumor necrosis factor | 0.718 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P42338 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.751 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | O95267 | RASGRP1 | RAS guanyl-releasing protein 1 | -0.716 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | Q08881 | ITK | Tyrosine-protein kinase ITK/TSK | -0.746 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | Q08881 | ITK | Tyrosine-protein kinase ITK/TSK | -0.736 | | P30304 | CDC25A | M-phase inducer phosphatase 1 | P19174 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | -0.762 | | P30304 | CDC25A | M-phase inducer phosphatase 1 | P16333 | NCK1 | Cytoplasmic protein NCK1 | -0.781 | | P30304 | CDC25A | M-phase inducer phosphatase 1 | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | -0.761 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | -0.852 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.775 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.722 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.771 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | -0.77 | | P30304 | CDC25A | M-phase inducer phosphatase 1 | P01730 | CD4 | T-cell surface glycoprotein CD4 | -0.708 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P01730 | CD4 | T-cell surface glycoprotein CD4 | -0.84 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | P01732 | CD8A | T-cell surface glycoprotein CD8 alpha chain | -0.722 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | Q13191 | CBLB | E3 ubiquitin-protein ligase CBL-B | -0.719 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | Q13191 | CBLB | E3 ubiquitin-protein ligase CBL-B | -0.734 | | P30304 | CDC25A | M-phase inducer phosphatase 1 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.767 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.825 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.779 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.817 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.889 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.795 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P49841 | GSK3B | Glycogen synthase kinase-3 beta | 0.812 | | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | P49841 | GSK3B | Glycogen synthase kinase-3 beta | 0.861 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P49841 | GSK3B | Glycogen synthase kinase-3 beta | 0.823 |
| | Estradiol-dienanthate | hsa04662 | B cell receptor signaling pathway | 2.80E-03 | 6 | P49841, P42338, P60033, P07948, P21854, Q8N149 | GSK3B, PIK3CB, CD81, LYN, CD72, LILRA2 | More | | | Estradiol-dienanthate | hsa04664 | Fc epsilon RI signaling pathway | 1.80E-02 | 4 | Q16539, P42338, P07948, P09917 | MAPK14, PIK3CB, LYN, ALOX5 | More | | | Estradiol-dienanthate | hsa04668 | TNF signaling pathway | 4.74E-02 | 3 | Q99941, P01584, O95429 | CREBL1, IL1B, BAG4 | More | | | Estradiol-dienanthate | hsa04710 | Circadian rhythm | 1.67E-02 | 2 | Q16526, Q9Y478 | CRY1, PRKAB1 | More | | | Estradiol-dienanthate | hsa04720 | Long-term potentiation | 2.35E-02 | 3 | P16298, P51812, Q02750 | PPP3CB, RPS6KA3, MAP2K1 | More | | | Estradiol-dienanthate | hsa04723 | Retrograde endocannabinoid signaling | 3.86E-02 | 4 | P63218, P50151, P48058, Q16539 | GNG5, GNG10, GRIA4, MAPK14 | More | | | Estradiol-dienanthate | hsa04724 | Glutamatergic synapse | 7.09E-03 | 5 | P48058, P43003, P63218, P50151, P15104 | GRIA4, SLC1A3, GNG5, GNG10, GLUL | More | | | Estradiol-dienanthate | hsa04728 | Dopaminergic synapse | 1.85E-03 | 7 | P14416, P63218, P50151, P49841, Q16539, P49407, P48058 | DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1, GRIA4 | More | | | Estradiol-dienanthate | hsa04750 | Inflammatory mediator regulation of TRP channels | 3.74E-02 | 3 | P01584, P51828, Q13557 | IL1B, ADCY7, CAMK2D | More | | | Estradiol-dienanthate | hsa04911 | Insulin secretion | 1.48E-02 | 3 | P51828, Q99941, Q13557 | ADCY7, CREBL1, CAMK2D | More | | | Estradiol-dienanthate | hsa04914 | Progesterone-mediated oocyte maturation | 7.70E-03 | 4 | Q17RY0, Q9Y6D9, P51812, Q02750 | CPEB4, MAD1L1, RPS6KA3, MAP2K1 | More | | | Estradiol-dienanthate | hsa04915 | Estrogen signaling pathway | 4.72E-02 | 4 | Q99941, P51828, P07900, P11142 | CREBL1, ADCY7, HSP90AA1, HSPA8 | More | | | Estradiol-dienanthate | hsa04920 | Adipocytokine signaling pathway | 4.31E-02 | 2 | Q9Y478, Q96RR4 | PRKAB1, CAMKK2 | More | | | Estradiol-dienanthate | hsa04925 | Aldosterone synthesis and secretion | 5.19E-03 | 4 | Q99941, P51828, Q13557, P23634 | CREBL1, ADCY7, CAMK2D, ATP2B4 | More | | | Estradiol-dienanthate | hsa04932 | Non-alcoholic fatty liver disease | 1.24E-02 | 6 | O43521, O75460, P01584, P13073, P12074, O15239 | BCL2L11, ERN1, IL1B, COX4I1, COX6A1, NDUFA1 | More | | | Estradiol-dienanthate | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.25E-02 | 3 | P84022, Q13485, P10415 | SMAD3, SMAD4, BCL2 | More | | | Estradiol-dienanthate | hsa04934 | Cushing syndrome | 3.48E-03 | 4 | Q99941, P51828, O15169, Q13557 | CREBL1, ADCY7, AXIN1, CAMK2D | More | | | Estradiol-dienanthate | hsa04971 | Gastric acid secretion | 1.48E-02 | 3 | P51828, P15311, Q13557 | ADCY7, VIL2, CAMK2D | More | | | Estradiol-dienanthate | hsa04973 | Carbohydrate digestion and absorption | 1.57E-02 | 2 | O43451, P42338 | MGAM, PIK3CB | More | | | Estradiol-dienanthate | hsa04975 | Fat digestion and absorption | 3.43E-02 | 1 | O14494 | PLPP1 | More | | | Estradiol-dienanthate | hsa05010 | Alzheimer disease | 1.56E-03 | 14 | Q92542, O15239, P05496, P13073, P12074, Q00535, O75460, P0DP23, P01584, O95197, O15169, P67870, P45880, P28070 | NCSTN, NDUFA1, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, CALM1, IL1B, RTN3, AXIN1, CSNK2B, VDAC2, PSMB4 | More | | | Estradiol-dienanthate | hsa05020 | Prion disease | 1.81E-02 | 7 | P01584, P46531, P11142, P05496, P12074, P45880, Q99941 | IL1B, NOTCH1, HSPA8, ATP5G1, COX6A1, VDAC2, CREBL1 | More | | | Estradiol-dienanthate | hsa05034 | Alcoholism | 4.54E-02 | 2 | P62807, O60814 | HIST1H2BC, H2BC12 | More | | | Estradiol-dienanthate | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 2.04E-03 | 4 | Q16539, P25024, P25025, P07948 | MAPK14, CXCR1, CXCR2, LYN | More | | | Estradiol-dienanthate | hsa05132 | Salmonella infection | 2.04E-02 | 4 | P25963, Q13489, P10415, Q9BQS8 | NFKBIA, BIRC3, BCL2, FYCO1 | More | | | Estradiol-dienanthate | hsa05135 | Yersinia infection | 1.98E-04 | 11 | Q05397, P51812, P13612, P06239, Q16539, Q02750, P01375, P42338, P49841, Q96JJ3, P01730 | PTK2, RPS6KA3, ITGA4, LCK, MAPK14, MAP2K1, TNF, PIK3CB, GSK3B, ELMO2, CD4 | More | | | Estradiol-dienanthate | hsa05144 | Malaria | 1.64E-03 | 5 | P60033, O60603, P01375, P35443, P26718 | CD81, TLR2, TNF, THBS4, KLRK1 | More | | | Estradiol-dienanthate | hsa05145 | Toxoplasmosis | 2.78E-02 | 3 | P25963, P10415, Q13489 | NFKBIA, BCL2, BIRC3 | More | | | Estradiol-dienanthate | hsa05161 | Hepatitis B | 8.49E-03 | 4 | P25963, Q13485, P10415, P84022 | NFKBIA, SMAD4, BCL2, SMAD3 | More | | | Estradiol-dienanthate | hsa05163 | Human cytomegalovirus infection | 2.50E-05 | 16 | P42338, P01375, P63218, P50151, P0DP23, Q8NHW4, Q08828, P23458, P49841, P14778, P01584, P61073, Q13651, P25025, Q16539, O00463 | PIK3CB, TNF, GNG5, GNG10, CALM1, CCL4L2, ADCY1, JAK1, GSK3B, IL1R1, IL1B, CXCR4, IL10RA, CXCR2, MAPK14, TRAF5 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P42338 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.751 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P01375 | TNF | Tumor necrosis factor | 0.718 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P63218 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | 0.733 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P63218 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | 0.727 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P50151 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | 0.875 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P50151 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | 0.743 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | P0DP23 | CALM1 | Calmodulin-1 | 0.762 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.727 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.727 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | Q08828 | ADCY1 | Adenylate cyclase type 1 | 0.829 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | 0.847 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P49841 | GSK3B | Glycogen synthase kinase-3 beta | 0.812 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P49841 | GSK3B | Glycogen synthase kinase-3 beta | 0.823 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P14778 | IL1R1 | Interleukin-1 receptor type 1 | 0.936 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P14778 | IL1R1 | Interleukin-1 receptor type 1 | 0.857 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | P01584 | IL1B | Interleukin-1 beta | 0.762 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | P61073 | CXCR4 | C-X-C chemokine receptor type 4 | 0.774 | | P62942 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | Q13651 | IL10RA | Interleukin-10 receptor subunit alpha | 0.769 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | Q13651 | IL10RA | Interleukin-10 receptor subunit alpha | -0.769 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | 0.86 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | P25025 | CXCR2 | C-X-C chemokine receptor type 2 | 0.929 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.817 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.795 | | Q9BPW9 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.719 | | P25024 | CXCR1 | C-X-C chemokine receptor type 1 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.788 |
| | Estradiol-dienanthate | hsa05169 | Epstein-Barr virus infection | 2.32E-02 | 9 | Q13547, O00463, Q16539, P42338, P07948, Q13761, P24522, P07766, P20963 | HDAC1, TRAF5, MAPK14, PIK3CB, LYN, RUNX3, GADD45A, CD3E, CD247 | More | | | Estradiol-dienanthate | hsa05170 | Human immunodeficiency virus 1 infection | 4.37E-02 | 4 | Q02750, P62879, P16298, Q05397 | MAP2K1, GNB2, PPP3CB, PTK2 | More | | | Estradiol-dienanthate | hsa05203 | Viral carcinogenesis | 2.13E-02 | 3 | Q15283, P62807, O60814 | RASA2, HIST1H2BC, H2BC12 | More | | | Estradiol-dienanthate | hsa05206 | MicroRNAs in cancer | 2.97E-03 | 6 | P15311, P21860, P61978, P46531, P63279, P22105 | VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXB | More | | | Estradiol-dienanthate | hsa05210 | Colorectal cancer | 1.78E-02 | 3 | P84022, Q13485, P10415 | SMAD3, SMAD4, BCL2 | More | | | Estradiol-dienanthate | hsa05212 | Pancreatic cancer | 4.21E-03 | 3 | P37173, P84022, Q13485 | TGFBR2, SMAD3, SMAD4 | More | | | Estradiol-dienanthate | hsa05220 | Chronic myeloid leukemia | 1.25E-02 | 3 | Q13485, P25963, P84022 | SMAD4, NFKBIA, SMAD3 | More | | | Estradiol-dienanthate | hsa05222 | Small cell lung cancer | 1.50E-02 | 3 | Q13489, P10415, P25963 | BIRC3, BCL2, NFKBIA | More | | | Estradiol-dienanthate | hsa05223 | Non-small cell lung cancer | 4.24E-02 | 3 | P19174, Q9HC35, O75293 | PLCG1, EML4, GADD45B | More | | | Estradiol-dienanthate | hsa05226 | Gastric cancer | 2.78E-02 | 3 | P84022, Q13485, P10415 | SMAD3, SMAD4, BCL2 | More | | | Estradiol-dienanthate | hsa05231 | Choline metabolism in cancer | 2.99E-03 | 3 | Q9Y259, P19174, P49619 | CHKB, PLCG1, DGKG | More | | | Estradiol-dienanthate | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 7.83E-05 | 9 | P42338, P19174, P07766, P20963, P06239, P42224, Q16539, Q9HC35, P01730 | PIK3CB, PLCG1, CD3E, CD247, LCK, STAT1, MAPK14, EML4, CD4 | More | | | Estradiol-dienanthate | hsa05322 | Systemic lupus erythematosus | 2.93E-02 | 2 | P62807, O60814 | HIST1H2BC, H2BC12 | More | | | Estradiol-dienanthate | hsa05340 | Primary immunodeficiency | 4.24E-02 | 3 | P01730, P07766, P06239 | CD4, CD3E, LCK | More | | | Estradiol-dienanthate | hsa05418 | Fluid shear stress and atherosclerosis | 3.61E-02 | 6 | Q16539, P10599, P14780, P01375, P14778, P27930 | MAPK14, TXN, MMP9, TNF, IL1R1, IL1R2 | More | |
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