PharmaCoNets of Eprosartan (SPCN: 103.73 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Eprosartanhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Eprosartanhsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Eprosartanhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Eprosartanhsa00071Fatty acid degradation4.66E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Eprosartanhsa00220Arginine biosynthesis2.86E-022P15104, P05089GLUL, ARG1More
Eprosartanhsa00310Lysine degradation2.59E-022Q96KQ7, P51648EHMT2, ALDH3A2More
Eprosartanhsa00500Starch and sucrose metabolism9.77E-064O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Eprosartanhsa00512Mucin type O-glycan biosynthesis4.86E-022O95395, Q9NY28GCNT3, GALNT8More
Eprosartanhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Eprosartanhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Eprosartanhsa00591Linoleic acid metabolism1.29E-031P11712CYP2C9More
Eprosartanhsa00630Glyoxylate and dicarboxylate metabolism9.21E-032P40925, P15104MDH1, GLULMore
Eprosartanhsa00730Thiamine metabolism7.19E-042P05186, P24666ALPL, ACP1More
Eprosartanhsa00770Pantothenate and CoA biosynthesis7.90E-033O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Eprosartanhsa00970Aminoacyl-tRNA biosynthesis1.58E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Eprosartanhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Eprosartanhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Eprosartanhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Eprosartanhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Eprosartanhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Eprosartanhsa01240Biosynthesis of cofactors2.95E-022P13716, P14618ALAD, PKM2More
Eprosartanhsa01524Platinum drug resistance1.13E-025P10415, Q13489, P78417, P23025, P43246BCL2, BIRC3, GSTO1, XPA, MSH2More
Eprosartanhsa02010ABC transporters2.17E-031Q8IZY2ABCA7More
Eprosartanhsa03008Ribosome biogenesis in eukaryotes2.60E-035Q9NYH9, P78345, Q9BVP2, O15381, Q9GZY0UTP6, RPP38, GNL3, NVL, NXF2; NXF2BMore
Eprosartanhsa03010Ribosome5.85E-048P62753, P25398, P32969, P46776, P62899, P18077, P61927, P36578RPS6, RPS12, RPL9, RPL27A, RPL31, RPL35A, RPL37, RPL4More
Eprosartanhsa03013RNA transport2.78E-0517O14980, P52298, Q09161, O14893, P61326, Q15287, Q7Z3B4, P35658, P68104, Q14152, O15371, O75822, P78345, P11940, Q14240, Q9Y6A5, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NUP54, NUP214, EEF1A1, EIF3A, EIF3D, EIF3J, RPP38, PABPC1, EIF4A2, TACC3, FXR1More
Eprosartanhsa03020RNA polymerase4.40E-022P24928, P62487POLR2A, POLR2GMore
Eprosartanhsa03040Spliceosome2.00E-0410Q14562, O43143, O60508, Q99633, Q13595, Q07955, Q01130, Q13243, Q9UMS4, P11142DHX8, DHX15, CDC40, PRPF18, TRA2A, SFRS1, SFRS2, SFRS5, PRPF19, HSPA8More
Eprosartanhsa03410Base excision repair7.59E-031P27695APEX1More
Eprosartanhsa04014Ras signaling pathway8.66E-037Q9NRA1, Q13009, P0DP23, P62873, P63218, P50151, P19174PDGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Eprosartanhsa04015Rap1 signaling pathway1.58E-026P20827, P49767, P63261, P25116, P0DP23, P17252EFNA1, VEGFC, ACTG1, F2R, CALM1, PRKCAMore
Eprosartanhsa04020Calcium signaling pathway1.16E-037Q16566, P17252, O15399, P25116, P0DP23, P23634, P49767CAMK4, PRKCA, GRIN2D, F2R, CALM1, ATP2B4, VEGFCMore
Eprosartanhsa04022cGMP-PKG signaling pathway2.55E-024P18848, Q8WYR1, P05141, P0DP24ATF4, PIK3R5, SLC25A5, CALM2More
Eprosartanhsa04024cAMP signaling pathway2.84E-025P0DP23, P23634, Q16566, O15399, P25116CALM1, ATP2B4, CAMK4, GRIN2D, F2RMore
Eprosartanhsa04060Cytokine-cytokine receptor interaction9.80E-0416P27930, P14778, P26842, Q9UHF4, Q13651, P16871, P25024, Q9UBD3, P47992, P02775, P09341, P32248, P51684, P18510, P09603, P01730IL1R2, IL1R1, CD27, IL20RA, IL10RA, IL7R, CXCR1, XCL2, XCL1, PPBP, CXCL1, CCR7, CCR6, IL1RN, CSF1, CD4More
Eprosartanhsa04061Viral protein interaction with cytokine and cytokine receptor2.08E-0411P51684, P32248, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, P14784, Q9UHF4CCR6, CCR7, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL2RB, IL20RAMore
Eprosartanhsa04062Chemokine signaling pathway1.80E-0619P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P49407, Q08881, Q13009, P14598, P42224, P25963, P49841CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, ARRB1, ITK, TIAM1, NCF1, STAT1, NFKBIA, GSK3BMore
Eprosartanhsa04064NF-kappa B signaling pathway3.08E-0313P10415, P51617, Q13546, P14778, P19174, Q04759, Q9UDY8, Q13077, P06239, P24522, P09341, P19875, Q06643BCL2, IRAK1, RIPK1, IL1R1, PLCG1, PRKCQ, MALT1, TRAF1, LCK, GADD45A, CXCL1, CXCL2, LTBMore
Eprosartanhsa04066HIF-1 signaling pathway3.40E-023Q09472, P07195, P10415EP300, LDHB, BCL2More
Eprosartanhsa04068FoxO signaling pathway3.52E-021Q96BR1SGK3More
Eprosartanhsa04070Phosphatidylinositol signaling system3.02E-037P19174, P0DP23, Q14643, P23743, O14732, P27987, P17252PLCG1, CALM1, ITPR1, DGKA, IMPA2, ITPKB, PRKCAMore
Eprosartanhsa04071Sphingolipid signaling pathway8.74E-0811P17252, P21453, Q9H228, P01375, Q13362, Q16537, Q9BX95, Q16539, P04637, P10415, Q9UQC2PRKCA, S1PR1, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, MAPK14, TP53, BCL2, GAB2More
Eprosartanhsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Eprosartanhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Eprosartanhsa04110Cell cycle2.06E-026Q9UJX4, O60566, Q09472, P24522, P04637, P49918ANAPC5, BUB1B, EP300, GADD45A, TP53, CDKN1CMore
Eprosartanhsa04141Protein processing in endoplasmic reticulum4.66E-0411P18848, Q12933, P30101, Q15436, P60604, Q99941, P11142, P07900, P08238, Q9H173, Q9UNL2ATF4, TRAF2, PDIA3, SEC23A, UBE2G2, CREBL1, HSPA8, HSP90AA1, HSP90AB1, SIL1, SSR3More
Eprosartanhsa04145Phagosome2.54E-0514O75015, P11215, P63261, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, P05164, O60603, P35443, P27824, P13765FCGR3B, ITGAM, ACTG1, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, CANX, HLA-DOBMore
Eprosartanhsa04151PI3K-Akt signaling pathway6.85E-0511P62753, O43521, P27348, P07900, Q8WYR1, Q16363, P22105, Q99941, P18848, O00141, Q6ZUJ8RPS6, BCL2L11, YWHAQ, HSP90AA1, PIK3R5, LAMA4, TNXB, CREBL1, ATF4, SGK, PIK3AP1More
Eprosartanhsa04210Apoptosis3.78E-0514P04637, P10415, O76075, P01375, Q9NR28, O75460, P24522, Q16548, Q13077, O43521, P43234, Q9UBR2, P18848, Q14643TP53, BCL2, DFFB, TNF, DIABLO, ERN1, GADD45A, BCL2A1, TRAF1, BCL2L11, CTSO, CTSZ, ATF4, ITPR1More
Eprosartanhsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Eprosartanhsa04217Necroptosis2.72E-048Q12933, P07900, P15104, P05141, P01584, P0C0S5, Q13557, Q9H444TRAF2, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, CAMK2D, CHMP4BMore
Eprosartanhsa04261Adrenergic signaling in cardiomyocytes2.85E-039P07550, P22694, P18848, Q13362, Q16537, P0DP23, P17252, P10415, P20020ADRB2, PRKACB, ATF4, PPP2R5C, PPP2R5E, CALM1, PRKCA, BCL2, ATP2B1More
Eprosartanhsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Eprosartanhsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Eprosartanhsa04371Apelin signaling pathway7.95E-047P62873, P63218, P50151, Q13370, Q14344, P84022, P0DP23GNB1, GNG5, GNG10, PDE3B, GNA13, SMAD3, CALM1More
Eprosartanhsa04390Hippo signaling pathway1.47E-025P63261, Q13485, Q9UJU2, O43623, Q13489ACTG1, SMAD4, LEF1, SNAI2, BIRC3More
Eprosartanhsa04510Focal adhesion3.21E-026Q15942, P17252, Q13489, P10415, P49767, P63261ZYX, PRKCA, BIRC3, BCL2, VEGFC, ACTG1More
Eprosartanhsa04512ECM-receptor interaction1.90E-022P26012, P16070ITGB8, CD44More
Eprosartanhsa04520Adherens junction3.36E-024Q13485, Q9UJU2, O43623, P63261SMAD4, LEF1, SNAI2, ACTG1More
Eprosartanhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Eprosartanhsa04540Gap junction1.30E-035P17252, Q13509, P68371, Q71U36, Q9NRA1PRKCA, TUBB3, TUBB2C, TUBA1A, PDGFCMore
Eprosartanhsa04610Complement and coagulation cascades4.27E-061P0C0L4C4AMore
Eprosartanhsa04612Antigen processing and presentation9.45E-059P13765, P48382, Q14953, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KIR2DS5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Eprosartanhsa04613Neutrophil extracellular trap formation7.63E-0620P17252, P11215, O60603, P05164, P08246, Q9UM07, Q92769, Q6FI13, Q93077, P62807, P33778, O60814, P68431, P14598, Q15080, O75015, P21730, P21462, O43315, Q16539PRKCA, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC2, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC3, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Eprosartanhsa04614Renin-angiotensin system1.52E-021P50052AGTR2More
Eprosartanhsa04623Cytosolic DNA-sensing pathway2.59E-022P01568, P25963IFNA21, NFKBIAMore
Eprosartanhsa04640Hematopoietic cell lineage3.09E-0410P13612, P14778, P27930, P11215, P25063, P07766, P01732, P01730, P09564, P09603ITGA4, IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD4, CD7, CSF1More
Eprosartanhsa04650Natural killer cell mediated cytotoxicity2.53E-0914P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, O75015, P26717, Q14953, P26715PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KIR2DS5, KLRC1More
Eprosartanhsa04657IL-17 signaling pathway2.40E-047P07900, Q12933, P49841, P19875, P14780, P80188, P01375HSP90AA1, TRAF2, GSK3B, CXCL2, MMP9, LCN2, TNFMore
Eprosartanhsa04658Th1 and Th2 cell differentiation3.52E-069Q04759, P07766, P20963, P19174, P01730, P06239, Q9UL17, P14784, Q13761PRKCQ, CD3E, CD247, PLCG1, CD4, LCK, TBX21, IL2RB, RUNX3More
Eprosartanhsa04659Th17 cell differentiation2.35E-0613P25963, Q04759, P19174, P01730, P06239, P42224, P14784, P14778, Q9UL17, P84022, P08238, P07766, P20963NFKBIA, PRKCQ, PLCG1, CD4, LCK, STAT1, IL2RB, IL1R1, TBX21, SMAD3, HSP90AB1, CD3E, CD247More
Eprosartanhsa04660T cell receptor signaling pathway2.21E-0514P01375, Q04759, P42338, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, PRKCQ, PIK3CB, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Eprosartanhsa04664Fc epsilon RI signaling pathway6.97E-034P04141, P07948, P19174, P09917CSF2, LYN, PLCG1, ALOX5More
Eprosartanhsa04666Fc gamma R-mediated phagocytosis2.22E-024P49006, P06396, P14598, P17252MARCKSL1, GSN, NCF1, PRKCAMore
Eprosartanhsa04668TNF signaling pathway1.46E-048P01375, Q12933, Q99941, P18848, P19875, P01584, P14780, P20333TNF, TRAF2, CREBL1, ATF4, CXCL2, IL1B, MMP9, TNFRSF1BMore
Eprosartanhsa04713Circadian entrainment2.18E-024P0DP23, P62873, P63218, P50151CALM1, GNB1, GNG5, GNG10More
Eprosartanhsa04720Long-term potentiation3.70E-045P17252, Q16566, P0DP23, O15399, Q14643PRKCA, CAMK4, CALM1, GRIN2D, ITPR1More
Eprosartanhsa04723Retrograde endocannabinoid signaling1.75E-025Q14643, P17252, P22694, Q16539, Q16718ITPR1, PRKCA, PRKACB, MAPK14, NDUFA5More
Eprosartanhsa04724Glutamatergic synapse1.18E-046P48058, P43003, P62873, P63218, P50151, P15104GRIA4, SLC1A3, GNB1, GNG5, GNG10, GLULMore
Eprosartanhsa04726Serotonergic synapse3.80E-024P62873, P63218, P50151, P09917GNB1, GNG5, GNG10, ALOX5More
Eprosartanhsa04727GABAergic synapse4.36E-044P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Eprosartanhsa04728Dopaminergic synapse3.73E-039P14416, P63218, P50151, P49841, Q99941, P18848, Q16539, Q13557, P49407DRD2, GNG5, GNG10, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1More
Eprosartanhsa04730Long-term depression4.86E-022Q14344, P07948GNA13, LYNMore
Eprosartanhsa04744Phototransduction9.21E-032P62873, P0DP23GNB1, CALM1More
Eprosartanhsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Eprosartanhsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Eprosartanhsa04911Insulin secretion5.41E-033Q99941, P18848, Q13557CREBL1, ATF4, CAMK2DMore
Eprosartanhsa04912GnRH signaling pathway3.80E-046P17252, Q16539, Q9Y6R4, Q14643, P0DP23, P22694PRKCA, MAPK14, MAP3K4, ITPR1, CALM1, PRKACBMore
Eprosartanhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Eprosartanhsa04916Melanogenesis3.55E-023P0DP23, Q9UJU2, P17252CALM1, LEF1, PRKCAMore
Eprosartanhsa04918Thyroid hormone synthesis1.44E-023Q99941, P18848, P02768CREBL1, ATF4, ALBMore
Eprosartanhsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Eprosartanhsa04921Oxytocin signaling pathway4.19E-024P0DP23, P17252, Q16566, P63261CALM1, PRKCA, CAMK4, ACTG1More
Eprosartanhsa04922Glucagon signaling pathway4.18E-022P14618, P06737PKM2, PYGLMore
Eprosartanhsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Eprosartanhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Eprosartanhsa04925Aldosterone synthesis and secretion1.83E-059Q14643, Q99941, P18848, P0DP23, P17252, Q16566, Q13557, P20020, P23634ITPR1, CREBL1, ATF4, CALM1, PRKCA, CAMK4, CAMK2D, ATP2B1, ATP2B4More
Eprosartanhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Eprosartanhsa04927Cortisol synthesis and secretion2.92E-033Q99941, P18848, P22694CREBL1, ATF4, PRKACBMore
Eprosartanhsa04928Parathyroid hormone synthesis, secretion and action3.75E-025Q14643, P22694, P23771, P17252, P10415ITPR1, PRKACB, GATA3, PRKCA, BCL2More
Eprosartanhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Eprosartanhsa04932Non-alcoholic fatty liver disease2.05E-035O43521, P18848, O75460, P01584, P13073BCL2L11, ATF4, ERN1, IL1B, COX4I1More
Eprosartanhsa04933AGE-RAGE signaling pathway in diabetic complications3.36E-024Q13485, P10415, P49767, P17252SMAD4, BCL2, VEGFC, PRKCAMore
Eprosartanhsa04934Cushing syndrome8.89E-044Q99941, P18848, O15169, Q13557CREBL1, ATF4, AXIN1, CAMK2DMore
Eprosartanhsa04964Proximal tubule bicarbonate reclamation2.17E-031P00918CA2More
Eprosartanhsa04966Collecting duct acid secretion1.43E-043P02730, P00918, Q9Y666SLC4A1, CA2, SLC12A7More
Eprosartanhsa04970Salivary secretion4.63E-058P07550, P22694, Q14643, P20020, P23634, P17252, P0DP23, P49913ADRB2, PRKACB, ITPR1, ATP2B1, ATP2B4, PRKCA, CALM1, CAMPMore
Eprosartanhsa04971Gastric acid secretion4.76E-023P17252, P63261, P0DP23PRKCA, ACTG1, CALM1More
Eprosartanhsa04972Pancreatic secretion1.00E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Eprosartanhsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Eprosartanhsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Eprosartanhsa04978Mineral absorption3.94E-022P23634, Q9BXS9ATP2B4, SLC26A6More
Eprosartanhsa05010Alzheimer disease2.78E-026P13073, O75460, P0DP24, P01584, P18848, P05141COX4I1, ERN1, CALM2, IL1B, ATF4, SLC25A5More
Eprosartanhsa05012Parkinson disease3.44E-0311P13073, P05141, P60604, O75460, P18848, P19174, P0DP23, P0DP24, Q71U36, Q13509, P68371COX4I1, SLC25A5, UBE2G2, ERN1, ATF4, PLCG1, CALM1, CALM2, TUBA1A, TUBB3, TUBB2CMore
Eprosartanhsa05014Amyotrophic lateral sclerosis4.31E-027O15399, P10415, Q13509, P68371, Q53GS7, P63261, Q9GZY0GRIN2D, BCL2, TUBB3, TUBB2C, GLE1, ACTG1, NXF2; NXF2BMore
Eprosartanhsa05016Huntington disease4.87E-025P13073, P24928, P62487, P05141, O75460COX4I1, POLR2A, POLR2G, SLC25A5, ERN1More
Eprosartanhsa05022Pathways of neurodegeneration - multiple diseases1.98E-027P13073, O75460, P18848, P05141, P20333, P01584, P0DP24COX4I1, ERN1, ATF4, SLC25A5, TNFRSF1B, IL1B, CALM2More
Eprosartanhsa05030Cocaine addiction4.36E-022Q99941, P18848CREBL1, ATF4More
Eprosartanhsa05031Amphetamine addiction3.32E-059O15399, P0DP23, Q16566, Q13557, P22694, Q99941, P18848, P17252, Q13547GRIN2D, CALM1, CAMK4, CAMK2D, PRKACB, CREBL1, ATF4, PRKCA, HDAC1More
Eprosartanhsa05032Morphine addiction2.18E-024P62873, P63218, P50151, Q13370GNB1, GNG5, GNG10, PDE3BMore
Eprosartanhsa05034Alcoholism3.90E-044Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Eprosartanhsa05120Epithelial cell signaling in Helicobacter pylori infection8.22E-069Q16539, P25963, Q13488, P09341, P19875, P19174, P25024, P25025, P07948MAPK14, NFKBIA, TCIRG1, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, LYNMore
Eprosartanhsa05130Pathogenic Escherichia coli infection3.19E-026Q71U36, P16333, Q13509, P68371, Q14344, P25963TUBA1A, NCK1, TUBB3, TUBB2C, GNA13, NFKBIAMore
Eprosartanhsa05132Salmonella infection2.13E-0517P51617, P25963, P08238, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, P51808, Q13561, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, HSP90AB1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Eprosartanhsa05133Pertussis3.22E-044P0DP23, P23528, P09871, P0C0L4CALM1, CFL1, C1S, C4AMore
Eprosartanhsa05134Legionellosis1.49E-035P25963, P11215, P11142, P09341, P19875NFKBIA, ITGAM, HSPA8, CXCL1, CXCL2More
Eprosartanhsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Eprosartanhsa05140Leishmaniasis2.02E-038P14598, P11215, P42224, O60603, P25963, P49006, P51617, Q15080NCF1, ITGAM, STAT1, TLR2, NFKBIA, MARCKSL1, IRAK1, NCF4More
Eprosartanhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Eprosartanhsa05144Malaria1.30E-057P60033, P69905, P68871, O60603, P01375, P35443, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Eprosartanhsa05146Amoebiasis3.23E-0712Q13751, P09341, P19875, P14778, P27930, P01375, P42338, P11215, P05089, P30679, P22694, P12814LAMB3, CXCL1, CXCL2, IL1R1, IL1R2, TNF, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1More
Eprosartanhsa05150Staphylococcus aureus infection1.31E-022P0C0L4, P13646C4A, KRT13More
Eprosartanhsa05152Tuberculosis1.26E-028Q13488, O75015, P48382, O60603, P10415, P13765, Q9UDY8, Q16539TCIRG1, FCGR3B, RFX5, TLR2, BCL2, HLA-DOB, MALT1, MAPK14More
Eprosartanhsa05161Hepatitis B2.86E-023Q99941, P18848, P27348CREBL1, ATF4, YWHAQMore
Eprosartanhsa05163Human cytomegalovirus infection1.72E-0414P01375, P25963, P62873, P63218, P50151, P0DP23, Q14344, P49841, P14778, P25025, Q16539, O00463, P30101, P01568TNF, NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5, PDIA3, IFNA21More
Eprosartanhsa05167Kaposi sarcoma-associated herpesvirus infection8.62E-0510P01568, P42224, P25963, P62873, P63218, P50151, P19174, P07948, P04141, P0DP23IFNA21, STAT1, NFKBIA, GNB1, GNG5, GNG10, PLCG1, LYN, CSF2, CALM1More
Eprosartanhsa05168Herpes simplex virus 1 infection2.35E-0315Q9UKJ0, P25963, P01568, Q9GZY0, P42224, Q07955, Q01130, Q13243, Q13489, P30101, Q13398, Q03923, O75820, Q9UDV6, P10415PILRB, NFKBIA, IFNA21, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, ZNF211, ZNF85, ZNF189, ZNF212, BCL2More
Eprosartanhsa05169Epstein-Barr virus infection2.15E-0310P13765, Q92769, P04637, Q13546, P10415, P24522, O60603, P29728, P51617, P09693HLA-DOB, HDAC2, TP53, RIPK1, BCL2, GADD45A, TLR2, OAS2, IRAK1, CD3GMore
Eprosartanhsa05170Human immunodeficiency virus 1 infection2.55E-0416P62873, P63218, P50151, P0DP23, P17252, Q13546, P30101, Q14643, P01568, P51617, P25963, O60603, P19174, P09693, P10415, Q9Y6Q5GNB1, GNG5, GNG10, CALM1, PRKCA, RIPK1, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, PLCG1, CD3G, BCL2, AP1M2More
Eprosartanhsa05171Coronavirus disease - COVID-191.51E-038P62753, P25398, P36578, P32969, P46776, P62899, P18077, P61927RPS6, RPS12, RPL4, RPL9, RPL27A, RPL31, RPL35A, RPL37More
Eprosartanhsa05200Pathways in cancer2.23E-0530P08238, P42224, P25963, P19174, P04637, Q9UJU2, P17252, Q09472, P43246, P84022, Q13485, P20585, P14923, P10415, Q13489, Q13077, P49767, P25116, P62873, P63218, P50151, Q14344, O95267, P78417, P24522, O75293, P0DP23, P01568, P14784, P16871HSP90AB1, STAT1, NFKBIA, PLCG1, TP53, LEF1, PRKCA, EP300, MSH2, SMAD3, SMAD4, MSH3, JUP, BCL2, BIRC3, TRAF1, VEGFC, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP1, GSTO1, GADD45A, GADD45B, CALM1, IFNA21, IL2RB, IL7RMore
Eprosartanhsa05202Transcriptional misregulation in cancer1.91E-0416Q12778, Q15532, P41732, P14780, P27930, P14923, Q16548, Q13489, Q13077, O15550, P04637, P35226, P05164, P08246, Q9C0K0, P24522FOXO1, SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, BIRC3, TRAF1, UTX, TP53, BMI1, MPO, ELA2, BCL11B, GADD45AMore
Eprosartanhsa05203Viral carcinogenesis1.62E-047Q12933, Q99941, P18848, P27348, Q15283, P62807, O60814TRAF2, CREBL1, ATF4, YWHAQ, RASA2, HIST1H2BC, H2BC12More
Eprosartanhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Eprosartanhsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Eprosartanhsa05210Colorectal cancer2.41E-024P10415, P04637, Q9UJU2, P24522BCL2, TP53, LEF1, GADD45AMore
Eprosartanhsa05212Pancreatic cancer1.05E-024P42224, P37173, P84022, O75293STAT1, TGFBR2, SMAD3, GADD45BMore
Eprosartanhsa05213Endometrial cancer1.91E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Eprosartanhsa05214Glioma1.12E-047P0DP23, Q16566, P17252, P04637, P19174, P24522, O75293CALM1, CAMK4, PRKCA, TP53, PLCG1, GADD45A, GADD45BMore
Eprosartanhsa05215Prostate cancer1.94E-024P10415, Q9UJU2, Q09472, P04637BCL2, LEF1, EP300, TP53More
Eprosartanhsa05216Thyroid cancer2.42E-043Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Eprosartanhsa05217Basal cell carcinoma1.56E-033Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Eprosartanhsa05222Small cell lung cancer1.94E-024P10415, Q13077, P04637, P24522BCL2, TRAF1, TP53, GADD45AMore
Eprosartanhsa05224Breast cancer4.32E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Eprosartanhsa05226Gastric cancer8.86E-035Q9UJU2, P04637, P24522, P14923, P10415LEF1, TP53, GADD45A, JUP, BCL2More
Eprosartanhsa05230Central carbon metabolism in cancer4.04E-022P07195, P04637LDHB, TP53More
Eprosartanhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, Q04759PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQMore
Eprosartanhsa05321Inflammatory bowel disease2.11E-036O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Eprosartanhsa05322Systemic lupus erythematosus1.49E-055P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Eprosartanhsa05332Graft-versus-host disease3.37E-045P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Eprosartanhsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Eprosartanhsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore
Eprosartanhsa05418Fluid shear stress and atherosclerosis2.49E-0311Q16539, P78417, P10599, P14780, P01375, P63261, P10415, P14778, P27930, P0DP23, Q92974MAPK14, GSTO1, TXN, MMP9, TNF, ACTG1, BCL2, IL1R1, IL1R2, CALM1, ARHGEF2More

Community members of Eprosartan (SDC: 4.55)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P27695APEX1DNANone(apurinic or apyrimidinic site) endonucleasePredicted10.4020.2210.12170.7647
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q15722LTB4RLeukotriene B4 receptor 1Predicted00.06770.219900.4736
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P61073CXCR4CNoneXNoneC chemokine receptor type 4Predicted10.28230.40180.6481.5927
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P51684CCR6CNoneC chemokine receptor type 6Predicted00.0850.17410.33040.7212
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
P46091GPR1ChemerinNonelike receptor 2Predicted00.24760.137200.3982
P32248CCR7CNoneC chemokine receptor type 7Predicted10.13910.04610.33040.4922
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P43657P2RY5Lysophosphatidic acid receptor 6Predicted00.75390.04480.37080.8373
P32302CXCR5CNoneXNoneC chemokine receptor type 5Predicted00.24550.04590.33040.545
Q99527GPER1GNoneprotein coupled estrogen receptor 1Predicted00.02490.12940.21380.485
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)