PharmaCoNets of Enzacamene (SPCN: 11.70 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Enzacamenehsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Enzacamenehsa00190Oxidative phosphorylation2.11E-043Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Enzacamenehsa00310Lysine degradation4.14E-021Q02809PLOD1More
Enzacamenehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Enzacamenehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Enzacamenehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Enzacamenehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Enzacamenehsa012102-Oxocarboxylic acid metabolism1.40E-021P50213IDH3AMore
Enzacamenehsa01230Biosynthesis of amino acids3.91E-023P51854, Q99707, P50213TKTL1, MTR, IDH3AMore
Enzacamenehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Enzacamenehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Enzacamenehsa04114Oocyte meiosis1.33E-024P51812, Q02750, P16298, Q17RY0RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Enzacamenehsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Enzacamenehsa04370VEGF signaling pathway2.68E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Enzacamenehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Enzacamenehsa04550Signaling pathways regulating pluripotency of stem cells2.16E-022P04628, P40189WNT1, IL6STMore
Enzacamenehsa04613Neutrophil extracellular trap formation2.18E-037P04908, Q93077, P62807, O60814, P68431, O43315, Q16539H2AC4; H2AC8, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, AQP9, MAPK14More
Enzacamenehsa04630JAK-STAT signaling pathway3.09E-033O75925, P40189, Q06124PIAS1, IL6ST, PTPN11More
Enzacamenehsa04650Natural killer cell mediated cytotoxicity2.94E-023P16298, P50591, Q02750PPP3CB, TNFSF10, MAP2K1More
Enzacamenehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Enzacamenehsa04720Long-term potentiation1.38E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Enzacamenehsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Enzacamenehsa04914Progesterone-mediated oocyte maturation2.94E-023Q17RY0, P51812, Q02750CPEB4, RPS6KA3, MAP2K1More
Enzacamenehsa04920Adipocytokine signaling pathway4.76E-032Q06124, Q9Y478PTPN11, PRKAB1More
Enzacamenehsa04931Insulin resistance1.48E-022Q06124, Q9Y478PTPN11, PRKAB1More
Enzacamenehsa04932Non-alcoholic fatty liver disease3.62E-023P49841, Q16718, O14521GSK3B, NDUFA5, SDHDMore
Enzacamenehsa04976Bile secretion3.32E-022O43315, P08183AQP9, ABCB1More
Enzacamenehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Enzacamenehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Enzacamenehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Enzacamenehsa05140Leishmaniasis4.50E-035P14598, O60603, P25963, P29350, Q15080NCF1, TLR2, NFKBIA, PTPN6, NCF4More
Enzacamenehsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Enzacamenehsa05170Human immunodeficiency virus 1 infection6.02E-035Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Enzacamenehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Enzacamenehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Enzacamenehsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Enzacamenehsa05226Gastric cancer8.67E-034Q02750, O15169, P04628, P10826MAP2K1, AXIN1, WNT1, RARBMore
Enzacamenehsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Enzacamenehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore

Community members of Enzacamene (SDC: 3.18)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
Q9GZR1SENP6SentrinNonespecific protease 6Predicted00.38440.078400.349
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
Q9Y478PRKAB15'NoneAMPNoneactivated protein kinase subunit betaNone1Predicted10.14780.10880.55640.8479
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)