PharmaCoNets of Droperidol (SPCN: 107.32 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Droperidolhsa00030Pentose phosphate pathway1.08E-053P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Droperidolhsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Droperidolhsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Droperidolhsa00190Oxidative phosphorylation2.35E-033Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Droperidolhsa00220Arginine biosynthesis1.43E-022P05089, P49448ARG1, GLUD2More
Droperidolhsa00230Purine metabolism1.81E-022P20839, Q02153IMPDH1, GUCY1B3More
Droperidolhsa00260Glycine, serine and threonine metabolism1.99E-021P22557ALAS2More
Droperidolhsa00330Arginine and proline metabolism4.86E-021P17707AMD1More
Droperidolhsa00350Tyrosine metabolism3.40E-021P28332ADH6More
Droperidolhsa00500Starch and sucrose metabolism6.40E-043O43451, P46976, P06737MGAM, GYG1, PYGLMore
Droperidolhsa00524Neomycin, kanamycin and gentamicin biosynthesis2.03E-021P35557GCKMore
Droperidolhsa00565Ether lipid metabolism3.94E-021Q8N661TMEM86BMore
Droperidolhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Droperidolhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Droperidolhsa00630Glyoxylate and dicarboxylate metabolism4.29E-032P40925, P15104MDH1, GLULMore
Droperidolhsa00730Thiamine metabolism3.64E-063Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Droperidolhsa00740Riboflavin metabolism4.03E-021P24666ACP1More
Droperidolhsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Droperidolhsa00830Retinol metabolism2.20E-024P00325, P11766, Q9BPW9, O75911ADH1B, ADH5, DHRS9, DHRS3More
Droperidolhsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Droperidolhsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Droperidolhsa00980Metabolism of xenobiotics by cytochrome P4508.40E-043P78417, P28332, P11712GSTO1, ADH6, CYP2C9More
Droperidolhsa00982Drug metabolism - cytochrome P4508.40E-043P11712, P78417, P28332CYP2C9, GSTO1, ADH6More
Droperidolhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Droperidolhsa01100Metabolic pathways4.43E-0223Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Droperidolhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Droperidolhsa01230Biosynthesis of amino acids2.22E-034P51854, P60891, Q99707, P37837TKTL1, PRPS1, MTR, TALDO1More
Droperidolhsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Droperidolhsa03008Ribosome biogenesis in eukaryotes1.88E-023O14980, O60832, Q9BVP2XPO1, DKC1, GNL3More
Droperidolhsa03013RNA transport2.48E-0513O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, P23588, Q9Y6A5XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, EIF4B, TACC3More
Droperidolhsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Droperidolhsa03040Spliceosome6.28E-036Q14562, O43143, O60508, Q07955, Q01130, Q13243DHX8, DHX15, CDC40, SFRS1, SFRS2, SFRS5More
Droperidolhsa03410Base excision repair7.59E-031P27695APEX1More
Droperidolhsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Droperidolhsa04020Calcium signaling pathway4.45E-023P0DP24, P51828, P23634CALM2, ADCY7, ATP2B4More
Droperidolhsa04024cAMP signaling pathway4.30E-037P51828, P42338, P0DP24, P0DP23, P23634, Q13370, Q13009ADCY7, PIK3CB, CALM2, CALM1, ATP2B4, PDE3B, TIAM1More
Droperidolhsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Droperidolhsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Droperidolhsa04064NF-kappa B signaling pathway8.22E-0515O00463, P14778, P01584, P01375, P19174, Q04759, Q13077, Q16548, P06239, Q8WV28, P24522, P09341, P19875, Q06643, Q9NQC7TRAF5, IL1R1, IL1B, TNF, PLCG1, PRKCQ, TRAF1, BCL2A1, LCK, BLNK, GADD45A, CXCL1, CXCL2, LTB, CYLDMore
Droperidolhsa04070Phosphatidylinositol signaling system4.86E-023P0DP23, P42338, P27987CALM1, PIK3CB, ITPKBMore
Droperidolhsa04071Sphingolipid signaling pathway3.75E-056P21453, Q9H228, P01375, Q13510, Q13362, Q9UQC2S1PR1, EDG8, TNF, ASAH1, PPP2R5C, GAB2More
Droperidolhsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Droperidolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Droperidolhsa04114Oocyte meiosis8.69E-034P0DP24, P51828, P27348, Q13362CALM2, ADCY7, YWHAQ, PPP2R5CMore
Droperidolhsa04120Ubiquitin mediated proteolysis2.51E-036Q14145, Q13042, P62837, Q15751, O95071, P0CG47KEAP1, CDC16, UBE2D2, HERC1, UBR5, UBBMore
Droperidolhsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Droperidolhsa04137Mitophagy - animal9.52E-032Q07817, P0CG47BCL2L1, UBBMore
Droperidolhsa04145Phagosome1.66E-039Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOBMore
Droperidolhsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Droperidolhsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Droperidolhsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Droperidolhsa04261Adrenergic signaling in cardiomyocytes1.05E-037P07550, P51828, P22694, P18848, Q13362, P0DP24, P23634ADRB2, ADCY7, PRKACB, ATF4, PPP2R5C, CALM2, ATP2B4More
Droperidolhsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Droperidolhsa04360Axon guidance1.71E-024P20827, O95631, P42338, P23528EFNA1, NTN1, PIK3CB, CFL1More
Droperidolhsa04380Osteoclast differentiation2.05E-0312Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P01584, P14778, O75015, Q8WV28, P01375, Q15080, P78324CYLD, GAB2, MAPK14, JAK1, LCK, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, SIRPAMore
Droperidolhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Droperidolhsa04612Antigen processing and presentation2.86E-057Q14953, P26715, P26717, Q07444, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, CD8A, TNFMore
Droperidolhsa04613Neutrophil extracellular trap formation8.84E-0419O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P04908, P0C0S5, Q93077, P62807, O60814, P68431, Q15080, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AC4; H2AC8, H2AFZ, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Droperidolhsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Droperidolhsa04625C-type lectin receptor signaling pathway8.11E-039Q9ULY5, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P0DP24, Q16539CLEC4E, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, CALM2, MAPK14More
Droperidolhsa04640Hematopoietic cell lineage2.62E-0314P13612, P14778, P27930, P11215, P15144, P11836, P25063, P07766, P09693, P01732, P09564, P13765, P01375, P01584ITGA4, IL1R1, IL1R2, ITGAM, ANPEP, MS4A1, CD24, CD3E, CD3G, CD8A, CD7, HLA-DOB, TNF, IL1BMore
Droperidolhsa04650Natural killer cell mediated cytotoxicity4.86E-0915P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Droperidolhsa04657IL-17 signaling pathway4.46E-059O00463, Q16539, P49841, P09341, P19875, P14780, P80188, P01375, P01584TRAF5, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNF, IL1BMore
Droperidolhsa04658Th1 and Th2 cell differentiation3.01E-0814Q04759, P07766, P20963, P09693, Q16539, P19174, P06239, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Droperidolhsa04659Th17 cell differentiation2.75E-0717Q04759, Q16539, P19174, P06239, P42224, P14784, P13765, P14778, P40189, Q9UL17, P23771, P01584, P08238, P07766, P09693, P20963, P23458PRKCQ, MAPK14, PLCG1, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL6ST, TBX21, GATA3, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Droperidolhsa04660T cell receptor signaling pathway1.78E-0614P01375, Q04759, P42338, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, PRKCQ, PIK3CB, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Droperidolhsa04666Fc gamma R-mediated phagocytosis2.25E-036P42338, P23528, P06396, O14494, P14598, P17252PIK3CB, CFL1, GSN, PLPP1, NCF1, PRKCAMore
Droperidolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Droperidolhsa04672Intestinal immune network for IgA production1.62E-023P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Droperidolhsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Droperidolhsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Droperidolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Droperidolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Droperidolhsa04744Phototransduction2.80E-022P62873, P0DP23GNB1, CALM1More
Droperidolhsa04750Inflammatory mediator regulation of TRP channels3.14E-0411P14778, P01584, P51828, P22694, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24IL1R1, IL1B, ADCY7, PRKACB, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2More
Droperidolhsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Droperidolhsa04912GnRH signaling pathway4.33E-026P51828, Q16539, Q9Y6R4, Q14643, P0DP24, P22694ADCY7, MAPK14, MAP3K4, ITPR1, CALM2, PRKACBMore
Droperidolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Droperidolhsa04914Progesterone-mediated oocyte maturation3.92E-023P42338, Q13370, P08238PIK3CB, PDE3B, HSP90AB1More
Droperidolhsa04916Melanogenesis4.80E-024P0DP23, Q9UJU2, P17252, P04628CALM1, LEF1, PRKCA, WNT1More
Droperidolhsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Droperidolhsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Droperidolhsa04924Renin secretion2.98E-034P22694, P07550, Q13370, P0DP23PRKACB, ADRB2, PDE3B, CALM1More
Droperidolhsa04925Aldosterone synthesis and secretion1.32E-023P51828, P0DP24, P23634ADCY7, CALM2, ATP2B4More
Droperidolhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Droperidolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Droperidolhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Droperidolhsa04932Non-alcoholic fatty liver disease2.44E-035P01375, P49841, P48023, Q16718, O14521TNF, GSK3B, FASLG, NDUFA5, SDHDMore
Droperidolhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Droperidolhsa04950Maturity onset diabetes of the young2.03E-021P35557GCKMore
Droperidolhsa04961Endocrine and other factor-regulated calcium reabsorption2.09E-022P23634, P62491ATP2B4, RAB11AMore
Droperidolhsa04970Salivary secretion1.84E-046P07550, P51828, P22694, P23634, P0DP24, P49913ADRB2, ADCY7, PRKACB, ATP2B4, CALM2, CAMPMore
Droperidolhsa04972Pancreatic secretion4.94E-033P23634, P51828, P62491ATP2B4, ADCY7, RAB11AMore
Droperidolhsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Droperidolhsa04976Bile secretion1.67E-033O43315, P22694, P08183AQP9, PRKACB, ABCB1More
Droperidolhsa05020Prion disease4.56E-036Q16718, O14521, Q92736, O60282, P49841, Q16539NDUFA5, SDHD, RYR2, KIF5C, GSK3B, MAPK14More
Droperidolhsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Droperidolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Droperidolhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Droperidolhsa05120Epithelial cell signaling in Helicobacter pylori infection1.96E-046Q16539, P09341, P19875, P19174, P25024, P25025MAPK14, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Droperidolhsa05132Salmonella infection9.17E-0312P51617, Q9UJU2, O00471, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371IRAK1, LEF1, EXOC5, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2CMore
Droperidolhsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Droperidolhsa05140Leishmaniasis1.93E-0310P13612, O75015, P23458, P13765, O60603, P01375, P01584, P49006, Q16539, Q15080ITGA4, FCGR3B, JAK1, HLA-DOB, TLR2, TNF, IL1B, MARCKSL1, MAPK14, NCF4More
Droperidolhsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Droperidolhsa05144Malaria1.74E-036P60033, O60603, P01375, P35443, P01584, P26718CD81, TLR2, TNF, THBS4, IL1B, KLRK1More
Droperidolhsa05146Amoebiasis1.81E-0714P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Droperidolhsa05152Tuberculosis5.68E-039Q13488, P0DP23, P48382, O60603, P10415, P13765, P01568, Q9UDY8, P51617TCIRG1, CALM1, RFX5, TLR2, BCL2, HLA-DOB, IFNA21, MALT1, IRAK1More
Droperidolhsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Droperidolhsa05163Human cytomegalovirus infection3.64E-027Q14643, P49841, P14778, P25025, Q16539, P04637, O00463ITPR1, GSK3B, IL1R1, CXCR2, MAPK14, TP53, TRAF5More
Droperidolhsa05168Herpes simplex virus 1 infection1.15E-028P42224, Q07955, Q01130, Q13243, P42338, Q13398, Q03923, Q9UDV6STAT1, SFRS1, SFRS2, SFRS5, PIK3CB, ZNF211, ZNF85, ZNF212More
Droperidolhsa05170Human immunodeficiency virus 1 infection5.94E-0312P62873, P0DP23, P17252, O00463, Q14643, P01568, P51617, O60603, P23528, P10415, Q93034, Q9Y6Q5GNB1, CALM1, PRKCA, TRAF5, ITPR1, IFNA21, IRAK1, TLR2, CFL1, BCL2, CUL5, AP1M2More
Droperidolhsa05200Pathways in cancer3.92E-029P42338, P08238, P42224, P43246, P14923, O75293, P0DP23, P14784, P40189PIK3CB, HSP90AB1, STAT1, MSH2, JUP, GADD45B, CALM1, IL2RB, IL6STMore
Droperidolhsa05202Transcriptional misregulation in cancer7.28E-0419Q12778, Q15532, P17844, P14780, P27930, P14923, Q16548, Q13489, Q13077, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, DDX5, MMP9, IL1R2, JUP, BCL2A1, BIRC3, TRAF1, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Droperidolhsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Droperidolhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Droperidolhsa05205Proteoglycans in cancer1.39E-0313Q13009, Q12955, Q14643, O75369, P14780, P17252, O60603, P01375, P23588, P04628, Q13635, P22694, P08962TIAM1, ANK3, ITPR1, FLNB, MMP9, PRKCA, TLR2, TNF, EIF4B, WNT1, PTCH1, PRKACB, CD63More
Droperidolhsa05212Pancreatic cancer1.72E-023P42338, P42224, O75293PIK3CB, STAT1, GADD45BMore
Droperidolhsa05214Glioma1.72E-023P0DP23, P42338, O75293CALM1, PIK3CB, GADD45BMore
Droperidolhsa05217Basal cell carcinoma3.50E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Droperidolhsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Droperidolhsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Droperidolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer7.34E-0612P42338, O95267, P19174, P07766, P20963, P09693, P06239, P23458, O60603, Q04759, Q16539, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, JAK1, TLR2, PRKCQ, MAPK14, CD4More
Droperidolhsa05320Autoimmune thyroid disease8.64E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Droperidolhsa05321Inflammatory bowel disease7.47E-047O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1BMore
Droperidolhsa05322Systemic lupus erythematosus1.49E-058P08311, P09871, Q93077, P62807, Q16778, O60814, P68431, P12814CTSG, C1S, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1More
Droperidolhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Droperidolhsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Droperidolhsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Droperidolhsa05418Fluid shear stress and atherosclerosis2.84E-0310Q16539, P42338, P14598, P10599, P14780, P04637, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, NCF1, TXN, MMP9, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Droperidol (SDC: 7.19)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorReported00.060410.47792.5081
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
Q07817BCL2L1BclNone2Nonelike protein 1Predicted10.08720.434911.9134
P10415BCL2Apoptosis regulator BclNone2Predicted10.03410.527112.0714
Q9UGN5PARP2Poly [ADPNoneribose] polymerase 2Predicted00.04350.26350.24610.7947
P27695APEX1DNANone(apurinic or apyrimidinic site) endonucleasePredicted10.4020.2210.12170.7647
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
O95551TTRAPTyrosylNoneDNA phosphodiesterase 2Predicted00.20920.256900.6184
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
Q13822ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Predicted00.1130.3050.00630.6729
O14786NRP1NeuropilinNone1Predicted10.38340.20260.51531.1123
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
DRD2P14416Ki0.25