PharmaCoNets of Delavirdine (SPCN: 253.13 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Delavirdinehsa00010Glycolysis / Gluconeogenesis1.89E-035P04075, P14550, P11766, P07195, P60174ALDOA, AKR1A1, ADH5, LDHB, TPI1More
Delavirdinehsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Delavirdinehsa00030Pentose phosphate pathway7.01E-114P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Delavirdinehsa00040Pentose and glucuronate interconversions3.53E-021O60701UGDHMore
Delavirdinehsa00051Fructose and mannose metabolism2.63E-055P15121, P19367, P08237, P60174, P04075AKR1B1, HK1, PFKM, TPI1, ALDOAMore
Delavirdinehsa00052Galactose metabolism4.25E-056P06280, P08237, O43451, P15121, P19367, Q14376GLA, PFKM, MGAM, AKR1B1, HK1, GALEMore
Delavirdinehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Delavirdinehsa00071Fatty acid degradation2.44E-045P11310, O75521, P00325, P11766, P33121ACADM, ECI2, ADH1B, ADH5, ACSL1More
Delavirdinehsa00100Steroid biosynthesis3.94E-021P35610SOAT1More
Delavirdinehsa00190Oxidative phosphorylation4.56E-064Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Delavirdinehsa00220Arginine biosynthesis1.97E-063P15104, P05089, P49448GLUL, ARG1, GLUD2More
Delavirdinehsa00230Purine metabolism3.35E-022Q7LG56, P51828RRM2B, ADCY7More
Delavirdinehsa00250Alanine, aspartate and glutamate metabolism6.84E-053Q96RQ9, P49448, P15104IL4I1, GLUD2, GLULMore
Delavirdinehsa00270Cysteine and methionine metabolism2.39E-022Q96RQ9, P40926IL4I1, MDH2More
Delavirdinehsa00280Valine, leucine and isoleucine degradation1.93E-046P55809, Q9HCC0, Q96RQ9, P05166, Q02252, P11310OXCT1, MCCC2, IL4I1, PCCB, ALDH6A1, ACADMMore
Delavirdinehsa00310Lysine degradation2.14E-057Q9NVH6, Q96KQ7, Q8NEZ4, Q13029, O15047, Q02809, P51648TMLHE, EHMT2, MLL3, PRDM2, SETD1A, PLOD1, ALDH3A2More
Delavirdinehsa00330Arginine and proline metabolism2.73E-021P17707AMD1More
Delavirdinehsa00380Tryptophan metabolism3.02E-021Q16613AANATMore
Delavirdinehsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Delavirdinehsa00471D-Glutamine and D-glutamate metabolism1.54E-032Q7Z3D6, P49448C14orf159, GLUD2More
Delavirdinehsa00500Starch and sucrose metabolism1.62E-094O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Delavirdinehsa00510N-Glycan biosynthesis1.10E-034O94777, P15907, Q9BVK2, Q9NR34DPM2, ST6GAL1, ALG8, MAN1C1More
Delavirdinehsa00513Various types of N-glycan biosynthesis4.83E-021Q9NR34MAN1C1More
Delavirdinehsa00520Amino sugar and nucleotide sugar metabolism1.75E-063Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Delavirdinehsa00524Neomycin, kanamycin and gentamicin biosynthesis2.03E-021P35557GCKMore
Delavirdinehsa00531Glycosaminoglycan degradation3.78E-021P15586GNSMore
Delavirdinehsa00562Inositol phosphate metabolism4.54E-045Q9NRR6, P27987, O14732, P19174, P42338INPP5E, ITPKB, IMPA2, PLCG1, PIK3CBMore
Delavirdinehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.28E-032O94777, Q14442DPM2, PIGHMore
Delavirdinehsa00564Glycerophospholipid metabolism1.25E-046P48651, Q9Y6K0, P35790, P23743, O14494, Q3LIE5PTDSS1, CEPT1, CHKA, DGKA, PLPP1, ADPRMMore
Delavirdinehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Delavirdinehsa00590Arachidonic acid metabolism2.48E-033P11712, P09917, P09960CYP2C9, ALOX5, LTA4HMore
Delavirdinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Delavirdinehsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Delavirdinehsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.27E-072P06865, O75752HEXA, B3GALNT1More
Delavirdinehsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Delavirdinehsa00620Pyruvate metabolism9.80E-044P40926, P07195, P14550, P11766MDH2, LDHB, AKR1A1, ADH5More
Delavirdinehsa00630Glyoxylate and dicarboxylate metabolism9.75E-124P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Delavirdinehsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Delavirdinehsa00670One carbon pool by folate1.72E-053O95954, P04818, Q99707FTCD, TYMS, MTRMore
Delavirdinehsa00730Thiamine metabolism1.05E-063Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Delavirdinehsa00740Riboflavin metabolism2.80E-032P30043, P24666BLVRB, ACP1More
Delavirdinehsa00750Vitamin B6 metabolism4.45E-021O00764PDXKMore
Delavirdinehsa00770Pantothenate and CoA biosynthesis7.20E-043O95498, Q6ZQY3, Q9NRN7VNN2, GADL1, AASDHPPTMore
Delavirdinehsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Delavirdinehsa00790Folate biosynthesis1.04E-023Q92820, P05186, P42330GGH, ALPL, AKR1C3More
Delavirdinehsa00830Retinol metabolism3.48E-055P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Delavirdinehsa00860Porphyrin and chlorophyll metabolism7.35E-053P36551, P53004, P30043CPOX, BLVRA, BLVRBMore
Delavirdinehsa00900Terpenoid backbone biosynthesis4.22E-022P49354, Q9UHG3FNTA, PCYOX1More
Delavirdinehsa00910Nitrogen metabolism4.40E-032P15104, P49448GLUL, GLUD2More
Delavirdinehsa00970Aminoacyl-tRNA biosynthesis8.86E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Delavirdinehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Delavirdinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Delavirdinehsa00983Drug metabolism - other enzymes1.07E-065P04183, P20839, P32320, P05164, Q16772TK1, IMPDH1, CDA, MPO, GSTA3More
Delavirdinehsa01040Biosynthesis of unsaturated fatty acids4.28E-021P22307SCP2More
Delavirdinehsa01100Metabolic pathways9.62E-0874Q9NR34, Q9Y234, P35790, P05089, P21953, Q16772, Q9UJ14, P15144, P30041, P15104, P19367, P42338, Q9Y217, P48426, P27987, Q96DU7, P22557, Q6ZQY3, P32320, Q08828, Q02153, P20839, P22748, P40926, P55809, P06280, O94777, Q16875, O43286, O43451, P53004, Q9Y6K0, P05186, P24666, P15121, P08237, Q86XP1, O95861, Q96RQ9, Q9HCC0, P33121, Q9UHK6, Q86VZ5, Q96G23, Q08477, P09917, P48651, Q9BVK2, P15907, Q8N4A0, P57054, Q14442, Q9UNP4, Q9H4F1, Q9BX95, Q9BRR6, P37837, P32321, P49448, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q969G6, P05166, P14927, P12074, P05496, Q99437, O15239, O15047, Q9NVH6MAN1C1, LIPT1, CHKA, ARG1, BCKDHB, GSTA3, GGTL3, ANPEP, PRDX6, GLUL, HK1, PIK3CB, MTMR6, PIP4K2A, ITPKB, ITPKC, ALAS2, GADL1, CDA, ADCY1, GUCY1B3, IMPDH1, CA4, MDH2, OXCT1, GLA, DPM2, PFKFB3, B4GALT5, MGAM, BLVRA, CEPT1, ALPL, ACP1, AKR1B1, PFKM, DGKH, BPNT1, IL4I1, MCCC2, ACSL1, AMACR, SGMS1, LASS2, CYP4F3, ALOX5, PTDSS1, ALG8, ST6GAL1, GALNT4, PIGP, PIGH, ST3GAL5, ST6GALNAC4, SGPP1, ADPGK, TALDO1, DCTD, GLUD2, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, RFK, PCCB, UQCRB, COX6A1, ATP5G1, ATP6V0B, NDUFA1, SETD1A, TMLHEMore
Delavirdinehsa01200Carbon metabolism2.13E-022P52209, P37837PGD, TALDO1More
Delavirdinehsa012102-Oxocarboxylic acid metabolism3.43E-021P50213IDH3AMore
Delavirdinehsa01212Fatty acid metabolism4.62E-022P33121, P11310ACSL1, ACADMMore
Delavirdinehsa01230Biosynthesis of amino acids1.96E-056P51854, P60891, Q99707, P50213, P05089, P37837TKTL1, PRPS1, MTR, IDH3A, ARG1, TALDO1More
Delavirdinehsa01240Biosynthesis of cofactors2.85E-047Q969G6, P13716, P36551, P22557, O60701, P14618, Q9Y234RFK, ALAD, CPOX, ALAS2, UGDH, PKM2, LIPT1More
Delavirdinehsa01521EGFR tyrosine kinase inhibitor resistance3.18E-042P04049, P08069RAF1, IGF1RMore
Delavirdinehsa01522Endocrine resistance1.02E-047P04049, Q9UM47, P04637, P42773, P08069, P10415, Q13323RAF1, NOTCH3, TP53, CDKN2C, IGF1R, BCL2, BIKMore
Delavirdinehsa01523Antifolate resistance2.16E-054P41440, Q92820, P04818, P01375SLC19A1, GGH, TYMS, TNFMore
Delavirdinehsa01524Platinum drug resistance2.37E-058Q13489, Q14790, P48023, P78417, P40692, P23025, P52701, P31751BIRC3, CASP8, FASLG, GSTO1, MLH1, XPA, MSH6, AKT2More
Delavirdinehsa02010ABC transporters2.17E-031Q8IZY2ABCA7More
Delavirdinehsa03008Ribosome biogenesis in eukaryotes2.03E-035Q9NYH9, O14980, O60832, P78345, Q9BVP2UTP6, XPO1, DKC1, RPP38, GNL3More
Delavirdinehsa03010Ribosome2.33E-1118P26373, P62753, P42677, P25398, P32969, P62917, P46776, Q9H0U6, Q07020, P62899, P62910, P18077, P61927, Q02878, P36578, P27635, P05386, P23396RPL13, RPS6, RPS27, RPS12, RPL9, RPL8, RPL27A, MRPL18, RPL18, RPL31, RPL32, RPL35A, RPL37, RPL6, RPL4, RPL10, RPLP1, RPS3More
Delavirdinehsa03013RNA transport5.30E-2830P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9H307, Q7Z3B4, P35658, P63279, P68104, P47813, O14602, Q14152, P55884, O15371, O75822, P78345, Q9H777, P11940, P20042, Q14240, Q9BZI7, P23588, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF1AY, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, ELAC1, PABPC1, EIF2S2, EIF4A2, UPF3B, EIF4B, TACC3, EIF2B1, FMR1, FXR1More
Delavirdinehsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Delavirdinehsa03020RNA polymerase8.11E-116P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Delavirdinehsa03022Basal transcription factors3.50E-023P20226, O00268, Q15544TBP, TAF4, TAF11More
Delavirdinehsa03040Spliceosome4.71E-1218Q14562, O43143, O60508, P08579, Q15427, P26368, O75940, P38159, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, SF3B4, U2AF2, SMNDC1, RBMX, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Delavirdinehsa03050Proteasome1.53E-031P55036PSMD4More
Delavirdinehsa03060Protein export1.16E-104Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Delavirdinehsa03320PPAR signaling pathway4.33E-022Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Delavirdinehsa03430Mismatch repair4.38E-021P20585MSH3More
Delavirdinehsa03450Non-homologous end-joining4.32E-021Q9NP87POLMMore
Delavirdinehsa03460Fanconi anemia pathway8.90E-043P40692, O60673, Q9UNA4MLH1, REV3L, POLIMore
Delavirdinehsa04010MAPK signaling pathway8.69E-054P04049, P08069, Q9H2K8, Q12933RAF1, IGF1R, TAOK3, TRAF2More
Delavirdinehsa04012ErbB signaling pathway2.36E-0710P21860, Q13153, P16333, Q13191, Q13557, P19174, O14944, P42338, P01106, P04049ERBB3, PAK1, NCK1, CBLB, CAMK2D, PLCG1, EREG, PIK3CB, MYC, RAF1More
Delavirdinehsa04014Ras signaling pathway4.67E-0613P04049, P31751, P42338, P20827, Q9NRA1, P49767, P08069, Q13009, P0DP23, P62873, P63218, P50151, P19174RAF1, AKT2, PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Delavirdinehsa04015Rap1 signaling pathway2.31E-0613P04049, P20827, Q9NRA1, P49767, P08069, P06213, P11215, Q13009, O00522, P42338, P31751, P0DP23, P19174RAF1, EFNA1, PDGFC, VEGFC, IGF1R, INSR, ITGAM, TIAM1, KRIT1, PIK3CB, AKT2, CALM1, PLCG1More
Delavirdinehsa04020Calcium signaling pathway1.39E-0916P27987, Q96DU7, Q08828, P21796, P45880, Q13557, P21860, P30679, P19174, P0DP24, P0DP23, P05141, P51828, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK2D, ERBB3, GNA15, PLCG1, CALM2, CALM1, SLC25A5, ADCY7, ATP2B4, PDGFC, VEGFCMore
Delavirdinehsa04022cGMP-PKG signaling pathway2.03E-0812Q02153, P04049, Q99941, P18848, P23634, P31751, Q08828, P51828, P05141, P45880, P0DP24, P0DP23GUCY1B3, RAF1, CREBL1, ATF4, ATP2B4, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, CALM2, CALM1More
Delavirdinehsa04024cAMP signaling pathway2.01E-059Q08828, P51828, P42338, P31751, P0DP23, P04049, Q13370, Q13009, Q13153ADCY1, ADCY7, PIK3CB, AKT2, CALM1, RAF1, PDE3B, TIAM1, PAK1More
Delavirdinehsa04060Cytokine-cytokine receptor interaction6.46E-0517P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, Q9HBE5, P78552, P25024, Q9UBD3, P47992, P09341, P19875, P80075, P01730, Q93038IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL21R, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CXCL2, CCL8, CD4, TNFRSF25More
Delavirdinehsa04061Viral protein interaction with cytokine and cytokine receptor2.86E-0610Q8NHW4, P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Delavirdinehsa04062Chemokine signaling pathway6.99E-0920P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q13009, P14598, P42224, P04049, P25963CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, TIAM1, NCF1, STAT1, RAF1, NFKBIAMore
Delavirdinehsa04064NF-kappa B signaling pathway8.29E-1823P10415, P51617, O00463, Q13546, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Delavirdinehsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Delavirdinehsa04068FoxO signaling pathway4.41E-054P04049, P08069, P48023, Q96BR1RAF1, IGF1R, FASLG, SGK3More
Delavirdinehsa04070Phosphatidylinositol signaling system5.75E-0814P19174, P0DP23, Q14643, P42338, O14986, P23743, P49619, Q86XP1, Q16760, P48426, O14732, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIK3CB, PIP5K1B, DGKA, DGKG, DGKH, DGKD, PIP4K2A, IMPA2, ITPKB, ITPKC, PRKCAMore
Delavirdinehsa04071Sphingolipid signaling pathway4.07E-0613P04049, P17252, P21453, Q9H228, P01375, Q96G23, Q13362, Q16537, Q9BX95, P04637, P10415, Q12933, Q02156RAF1, PRKCA, S1PR1, EDG8, TNF, LASS2, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2, TRAF2, PRKCEMore
Delavirdinehsa04072Phospholipase D signaling pathway2.30E-0616P04049, P31751, P42338, Q9UQC2, P43657, P25024, P25025, P19174, O14986, Q14344, Q15438, Q08828, P51828, P23743, Q16760, Q9NRA1RAF1, AKT2, PIK3CB, GAB2, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNA13, PSCD1, ADCY1, ADCY7, DGKA, DGKD, PDGFCMore
Delavirdinehsa04080Neuroactive ligand-receptor interaction1.97E-0411P08311, P78334, Q15722, P21453, Q9H228, P43657, P21462, P21730, P30939, P07550, P35318CTSG, GABRE, LTB4R, S1PR1, EDG8, P2RY5, FPR1, C5AR1, HTR1F, ADRB2, ADMMore
Delavirdinehsa04110Cell cycle1.19E-0813Q9UBD5, P30260, P06493, O60566, Q14683, O75293, P04637, P49918, P30304, P33981, P42773, P01106, Q13547ORC3, CDC27, CDK1, BUB1B, SMC1A, GADD45B, TP53, CDKN1C, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Delavirdinehsa04114Oocyte meiosis5.73E-1011Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Delavirdinehsa04115p53 signaling pathway2.54E-023O15151, Q13315, P10415MDM4, ATM, BCL2More
Delavirdinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Delavirdinehsa04136Autophagy - other4.46E-052O94817, Q9H1Y0ATG12, ATG5More
Delavirdinehsa04137Mitophagy - animal1.41E-033P67870, P19532, P18848CSNK2B, TFE3, ATF4More
Delavirdinehsa04140Autophagy - animal3.90E-0515P08069, Q9Y4H2, P42338, P31751, P04049, Q7L523, Q9NQL2, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, IRS2, PIK3CB, AKT2, RAF1, RRAGA, RRAGD, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Delavirdinehsa04141Protein processing in endoplasmic reticulum8.83E-0716P18848, Q12933, P30101, P07384, O95487, Q15436, P60604, Q99941, O75460, P11142, Q9H3Z4, P07900, P08238, Q9NR31, O95816, Q9UNL2ATF4, TRAF2, PDIA3, CAPN1, SEC24B, SEC23A, UBE2G2, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, BAG2, SSR3More
Delavirdinehsa04142Lysosome1.11E-0511O14773, P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, Q9NRA2, P49279, P61916, Q04900TPP1, HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC17A5, SLC11A1, NPC2, CD164More
Delavirdinehsa04144Endocytosis8.76E-0719Q13191, P0DMV8, P11142, Q9H444, O43633, O75351, P62491, P25024, Q96B97, P43250, Q6WKZ4, Q15438, Q8WU79, Q14161, P14784, O95219, O75154, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, CHMP2A, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, RAB11FIP1, PSCD1, SMAP1L, GIT2, IL2RB, SNX4, RAB11FIP3, SNX12, SNX5More
Delavirdinehsa04145Phagosome4.61E-0410O75015, Q15080, P14598, Q13509, P68371, P05164, P78380, O60603, P35443, P13765FCGR3B, NCF4, NCF1, TUBB3, TUBB2C, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Delavirdinehsa04146Peroxisome1.95E-036O00623, O96011, P56589, Q9UKG9, O75521, P33121PEX12, PEX11B, PEX3, CROT, ECI2, ACSL1More
Delavirdinehsa04150mTOR signaling pathway5.20E-042P08069, P04049IGF1R, RAF1More
Delavirdinehsa04151PI3K-Akt signaling pathway3.15E-0831P62753, P42338, P21860, P01106, O43521, P04637, P27348, P20827, Q9NRA1, P49767, Q13362, P07900, P08238, P62873, P63218, P50151, P61952, O15335, P02452, P24821, Q16363, P22105, P14784, P23458, P01568, Q99941, P18848, Q96BR1, O00141, Q6ZUJ8, P56279RPS6, PIK3CB, ERBB3, MYC, BCL2L11, TP53, YWHAQ, EFNA1, PDGFC, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, GNB1, GNG5, GNG10, GNG11, CHAD, COL1A1, TNC, LAMA4, TNXB, IL2RB, JAK1, IFNA21, CREBL1, ATF4, SGK3, SGK, PIK3AP1, TCL1AMore
Delavirdinehsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Delavirdinehsa04210Apoptosis1.10E-034Q14790, P48023, P42575, P04049CASP8, FASLG, CASP2, RAF1More
Delavirdinehsa04211Longevity regulating pathway2.60E-046P31751, P08069, Q08828, P51828, P18848, Q96RR4AKT2, IGF1R, ADCY1, ADCY7, ATF4, CAMKK2More
Delavirdinehsa04213Longevity regulating pathway - multiple species1.70E-089P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Delavirdinehsa04217Necroptosis3.63E-1225P01375, Q12933, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, Q93077, Q13557, Q9H444, O43633, O75351, P45880, Q08752TNF, TRAF2, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, CAMK2D, CHMP4B, CHMP2A, VPS4B, VDAC2, PPIDMore
Delavirdinehsa04218Cellular senescence3.45E-0511P01106, P31751, P04049, P30281, O75293, P30304, P06493, P0DP23, P01889, P10321, P12236MYC, AKT2, RAF1, CCND3, GADD45B, CDC25A, CDK1, CALM1, HLA-B, HLA-C, SLC25A6More
Delavirdinehsa04260Cardiac muscle contraction4.20E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Delavirdinehsa04261Adrenergic signaling in cardiomyocytes1.31E-0916P67936, Q08828, P51828, P31751, Q99941, P18848, Q13362, Q14738, Q16537, P0DP24, P0DP23, Q13557, P17252, P10415, P20020, P23634TPM4, ADCY1, ADCY7, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, PPP2R5E, CALM2, CALM1, CAMK2D, PRKCA, BCL2, ATP2B1, ATP2B4More
Delavirdinehsa04270Vascular smooth muscle contraction1.71E-0611P24723, Q04759, Q14643, P0DP23, P04049, Q08828, P51828, P22694, P35579, P35749, P35318PRKCH, PRKCQ, ITPR1, CALM1, RAF1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Delavirdinehsa04310Wnt signaling pathway2.28E-045P30279, Q13485, O43318, P17612, P67870CCND2, SMAD4, MAP3K7, PRKACA, CSNK2BMore
Delavirdinehsa04330Notch signaling pathway4.48E-054Q92542, P49768, P46531, Q9UM47NCSTN, PSEN1, NOTCH1, NOTCH3More
Delavirdinehsa04340Hedgehog signaling pathway2.58E-034P17612, P22694, Q13635, P10415PRKACA, PRKACB, PTCH1, BCL2More
Delavirdinehsa04360Axon guidance3.08E-0713P16298, Q05397, P16333, P20827, O95631, Q13873, P42338, P23528, P04049, P19174, Q06124, O14639, P24844PPP3CB, PTK2, NCK1, EFNA1, NTN1, BMPR2, PIK3CB, CFL1, RAF1, PLCG1, PTPN11, ABLIM1, MYL9More
Delavirdinehsa04370VEGF signaling pathway6.18E-137P19174, P16298, P31751, P42338, Q05397, Q02750, P04049PLCG1, PPP3CB, AKT2, PIK3CB, PTK2, MAP2K1, RAF1More
Delavirdinehsa04371Apelin signaling pathway1.82E-0614P62873, P63218, P50151, P61952, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, P62753, P0DP23, P0DP24GNB1, GNG5, GNG10, GNG11, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, RPS6, CALM1, CALM2More
Delavirdinehsa04380Osteoclast differentiation6.46E-1114Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Delavirdinehsa04390Hippo signaling pathway3.37E-055O95835, P04628, Q9UJU2, O43623, Q13489LATS1, WNT1, LEF1, SNAI2, BIRC3More
Delavirdinehsa04392Hippo signaling pathway - multiple species2.11E-053O95835, Q13153, Q6V0I7LATS1, PAK1, FAT4More
Delavirdinehsa04510Focal adhesion1.63E-035Q15942, P51636, P30281, P04049, P08069ZYX, CAV2, CCND3, RAF1, IGF1RMore
Delavirdinehsa04512ECM-receptor interaction2.77E-056P02452, P24821, P07359, P26012, P08514, P16070COL1A1, TNC, GP1BA, ITGB8, ITGA2B, CD44More
Delavirdinehsa04520Adherens junction1.81E-033Q13485, O43318, P08069SMAD4, MAP3K7, IGF1RMore
Delavirdinehsa04530Tight junction1.74E-036P63261, P16989, P56750, Q9Y478, Q92974, Q14247ACTG1, CSDA, CLDN17, PRKAB1, ARHGEF2, CTTNMore
Delavirdinehsa04540Gap junction8.97E-044Q13509, P68371, P04049, Q9NRA1TUBB3, TUBB2C, RAF1, PDGFCMore
Delavirdinehsa04550Signaling pathways regulating pluripotency of stem cells1.61E-035Q13873, P04049, Q02750, P08069, Q86SE9BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Delavirdinehsa04610Complement and coagulation cascades1.61E-125P09871, P00734, P0C0L4, P20023, P05107C1S, F2, C4A, CR2, ITGB2More
Delavirdinehsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Delavirdinehsa04612Antigen processing and presentation7.58E-1012P13765, P48382, P01730, P26715, P26717, Q07444, Q13241, O43908, P01732, P30101, P11142, P01375HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, PDIA3, HSPA8, TNFMore
Delavirdinehsa04613Neutrophil extracellular trap formation2.71E-0935P42338, P19174, P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q6FI13, Q99878, Q93077, P62807, P33778, Q93079, Q16778, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539PIK3CB, PLCG1, PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, HIST1H2BC, H2BC3, H2BC9, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Delavirdinehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Delavirdinehsa04620Toll-like receptor signaling pathway6.81E-068Q13546, P01568, P01584, P31751, P42224, P25963, P42338, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, STAT1, NFKBIA, PIK3CB, CCL4L2More
Delavirdinehsa04621NOD-like receptor signaling pathway2.55E-0312P01584, P07900, Q14643, P23458, P45880, P10599, P43490, O00463, P29728, P01375, P09341, P12838IL1B, HSP90AA1, ITPR1, JAK1, VDAC2, TXN, PBEF1, TRAF5, OAS2, TNF, CXCL1, DEFA4More
Delavirdinehsa04622RIG-I-like receptor signaling pathway1.29E-075P01568, Q9NQC7, Q13546, Q12933, P10145IFNA21, CYLD, RIPK1, TRAF2, IL8More
Delavirdinehsa04623Cytosolic DNA-sensing pathway3.02E-126P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Delavirdinehsa04625C-type lectin receptor signaling pathway3.16E-1016Q9ULY5, P04049, Q13153, P01584, Q9NQC7, P42224, P20749, P25963, Q14643, P01375, Q13191, P42338, P31751, P0DP24, P0DP23, Q16539CLEC4E, RAF1, PAK1, IL1B, CYLD, STAT1, BCL3, NFKBIA, ITPR1, TNF, CBLB, PIK3CB, AKT2, CALM2, CALM1, MAPK14More
Delavirdinehsa04630JAK-STAT signaling pathway1.01E-048P01106, P31751, P42224, P23458, P14784, P16871, Q13651, P04049MYC, AKT2, STAT1, JAK1, IL2RB, IL7R, IL10RA, RAF1More
Delavirdinehsa04640Hematopoietic cell lineage2.74E-1220P13612, P07359, P08514, P21926, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P01584ITGA4, GP1BA, ITGA2B, CD9, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, IL1BMore
Delavirdinehsa04650Natural killer cell mediated cytotoxicity2.34E-2219P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, P04049, Q13153, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, PAK1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Delavirdinehsa04657IL-17 signaling pathway4.20E-0814P25963, P07900, P08238, O00463, Q12933, Q07955, Q16539, P49841, P09341, P14780, P80188, P01375, P06702, P01584NFKBIA, HSP90AA1, HSP90AB1, TRAF5, TRAF2, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF, S100A9, IL1BMore
Delavirdinehsa04658Th1 and Th2 cell differentiation5.96E-3418P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, Q9UM47, P13765, P23458, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, JAK1, RUNX3More
Delavirdinehsa04659Th17 cell differentiation8.36E-2621P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Delavirdinehsa04660T cell receptor signaling pathway3.98E-2419P01375, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, Q13153, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, PAK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Delavirdinehsa04662B cell receptor signaling pathway1.45E-1314P25963, P31751, P42338, P20023, P60033, P13164, P16298, Q8WV28, P07948, P11912, P21854, Q8N149, Q02750, P04049NFKBIA, AKT2, PIK3CB, CR2, CD81, IFITM1, PPP3CB, BLNK, LYN, CD79A, CD72, LILRA2, MAP2K1, RAF1More
Delavirdinehsa04664Fc epsilon RI signaling pathway9.21E-089P01375, P31751, Q16539, P42338, Q9UQC2, P07948, P19174, P04049, P09917TNF, AKT2, MAPK14, PIK3CB, GAB2, LYN, PLCG1, RAF1, ALOX5More
Delavirdinehsa04666Fc gamma R-mediated phagocytosis2.49E-0511P08637, O75015, P07948, P42338, P19174, P04049, P23528, P49006, P06396, P14598, P17252FCGR3A, FCGR3B, LYN, PIK3CB, PLCG1, RAF1, CFL1, MARCKSL1, GSN, NCF1, PRKCAMore
Delavirdinehsa04668TNF signaling pathway5.86E-0611P01375, Q12933, O00463, Q16539, Q99941, P18848, P01584, P20749, P14780, P20333, O95429TNF, TRAF2, TRAF5, MAPK14, CREBL1, ATF4, IL1B, BCL3, MMP9, TNFRSF1B, BAG4More
Delavirdinehsa04710Circadian rhythm4.86E-021O15516CLOCKMore
Delavirdinehsa04713Circadian entrainment3.32E-0710P0DP23, P0DP24, Q13557, Q02153, P62873, P63218, P50151, P61952, Q08828, P51828CALM1, CALM2, CAMK2D, GUCY1B3, GNB1, GNG5, GNG10, GNG11, ADCY1, ADCY7More
Delavirdinehsa04714Thermogenesis2.17E-037Q16539, P15336, P63261, P33121, Q9Y478, Q16718, O14521MAPK14, ATF2, ACTG1, ACSL1, PRKAB1, NDUFA5, SDHDMore
Delavirdinehsa04720Long-term potentiation1.15E-1012P17252, Q13557, P16298, P0DP23, P0DP24, Q15418, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, CAMK2D, PPP3CB, CALM1, CALM2, RPS6KA1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Delavirdinehsa04721Synaptic vesicle cycle9.45E-042Q13488, P31645TCIRG1, SLC6A4More
Delavirdinehsa04722Neurotrophin signaling pathway1.76E-0610Q05655, P31751, P04049, P49841, O43524, P48023, P52566, P51617, P10415, P0DP23PRKCD, AKT2, RAF1, GSK3B, FOXO3, FASLG, ARHGDIB, IRAK1, BCL2, CALM1More
Delavirdinehsa04723Retrograde endocannabinoid signaling3.71E-024P62873, P61952, Q08828, O15239GNB1, GNG11, ADCY1, NDUFA1More
Delavirdinehsa04724Glutamatergic synapse2.59E-067O15399, Q08828, P62873, P63218, P50151, P61952, P15104GRIN2D, ADCY1, GNB1, GNG5, GNG10, GNG11, GLULMore
Delavirdinehsa04725Cholinergic synapse5.31E-0710Q08828, P51828, P62873, P63218, P50151, P61952, P18848, Q13557, P42338, P31751ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, ATF4, CAMK2D, PIK3CB, AKT2More
Delavirdinehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Delavirdinehsa04727GABAergic synapse2.45E-099Q08828, P51828, P62873, P63218, P50151, P61952, P15104, P46459, Q15111ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, NSF, PLCL1More
Delavirdinehsa04728Dopaminergic synapse9.23E-0916P62873, P50151, P61952, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP24, P0DP23, O15516, P48058GNB1, GNG10, GNG11, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM2, CALM1, CLOCK, GRIA4More
Delavirdinehsa04730Long-term depression1.25E-042P08069, P04049IGF1R, RAF1More
Delavirdinehsa04740Olfactory transduction4.52E-054P62873, Q13557, P0DP23, P0DP24GNB1, CAMK2D, CALM1, CALM2More
Delavirdinehsa04742Taste transduction1.18E-032P30939, P17612HTR1F, PRKACAMore
Delavirdinehsa04744Phototransduction1.45E-083P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Delavirdinehsa04750Inflammatory mediator regulation of TRP channels2.57E-1314P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Delavirdinehsa04810Regulation of actin cytoskeleton2.03E-0310P12814, Q13009, P04049, P42338, P11215, P16144, Q14344, Q9NRA1, P60709, P01042ACTN1, TIAM1, RAF1, PIK3CB, ITGAM, ITGB4, GNA13, PDGFC, ACTB, KNG1More
Delavirdinehsa04910Insulin signaling pathway2.40E-053P0DP23, P04049, P31751CALM1, RAF1, AKT2More
Delavirdinehsa04911Insulin secretion4.38E-085Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Delavirdinehsa04912GnRH signaling pathway6.87E-0712P17252, Q08828, P51828, P18848, Q16539, Q9Y6R4, Q14643, P0DP24, P0DP23, P22694, P04049, P45985PRKCA, ADCY1, ADCY7, ATF4, MAPK14, MAP3K4, ITPR1, CALM2, CALM1, PRKACB, RAF1, MAP2K4More
Delavirdinehsa04913Ovarian steroidogenesis8.40E-042P06213, P08069INSR, IGF1RMore
Delavirdinehsa04914Progesterone-mediated oocyte maturation6.38E-1010P08069, Q17RY0, P42338, Q13370, Q9Y6D9, P30304, P08238, P51812, Q02750, P04049IGF1R, CPEB4, PIK3CB, PDE3B, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Delavirdinehsa04915Estrogen signaling pathway1.37E-1012P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, P0DP24, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Delavirdinehsa04916Melanogenesis7.31E-044P0DP23, Q08828, P51828, P04049CALM1, ADCY1, ADCY7, RAF1More
Delavirdinehsa04917Prolactin signaling pathway3.49E-042P31751, P04049AKT2, RAF1More
Delavirdinehsa04918Thyroid hormone synthesis2.47E-045Q08828, Q99941, P18848, P02768, P05543ADCY1, CREBL1, ATF4, ALB, SERPINA7More
Delavirdinehsa04919Thyroid hormone signaling pathway1.21E-047P19174, P04049, P42224, P60709, Q13547, Q9UM47, P01106PLCG1, RAF1, STAT1, ACTB, HDAC1, NOTCH3, MYCMore
Delavirdinehsa04920Adipocytokine signaling pathway3.41E-033Q06124, Q9Y478, P31751PTPN11, PRKAB1, AKT2More
Delavirdinehsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Delavirdinehsa04922Glucagon signaling pathway4.86E-044P14618, P06737, P31751, P0DP23PKM2, PYGL, AKT2, CALM1More
Delavirdinehsa04923Regulation of lipolysis in adipocytes4.29E-077Q08828, P51828, P07550, P06213, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, INSR, PIK3CB, IRS2, AKT2More
Delavirdinehsa04924Renin secretion2.92E-065P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Delavirdinehsa04925Aldosterone synthesis and secretion1.87E-1111Q14643, Q99941, P18848, Q08828, P51828, P0DP24, P0DP23, P17252, Q13557, P20020, P23634ITPR1, CREBL1, ATF4, ADCY1, ADCY7, CALM2, CALM1, PRKCA, CAMK2D, ATP2B1, ATP2B4More
Delavirdinehsa04926Relaxin signaling pathway6.22E-0915P31751, P25963, P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P49767, Q08828, P51828, P04049, P30679, P49407AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, VEGFC, ADCY1, ADCY7, RAF1, GNA15, ARRB1More
Delavirdinehsa04927Cortisol synthesis and secretion2.32E-054Q99941, P18848, Q08828, P51828CREBL1, ATF4, ADCY1, ADCY7More
Delavirdinehsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Delavirdinehsa04929GnRH secretion6.93E-064P42338, P31751, P49407, P04049PIK3CB, AKT2, ARRB1, RAF1More
Delavirdinehsa04930Type II diabetes mellitus6.29E-053P06213, Q05655, Q02156INSR, PRKCD, PRKCEMore
Delavirdinehsa04932Non-alcoholic fatty liver disease2.08E-1214P31751, P01375, P49841, Q14790, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, O95298, P19404AKT2, TNF, GSK3B, CASP8, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2, NDUFV2More
Delavirdinehsa04934Cushing syndrome6.22E-096Q99941, P18848, Q08828, P51828, O15169, Q13557CREBL1, ATF4, ADCY1, ADCY7, AXIN1, CAMK2DMore
Delavirdinehsa04935Growth hormone synthesis, secretion and action5.87E-046Q08828, P51828, P04049, P18848, P31751, P45985ADCY1, ADCY7, RAF1, ATF4, AKT2, MAP2K4More
Delavirdinehsa04940Type I diabetes mellitus7.38E-044P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Delavirdinehsa04950Maturity onset diabetes of the young2.03E-021P35557GCKMore
Delavirdinehsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Delavirdinehsa04964Proximal tubule bicarbonate reclamation2.17E-031P00918CA2More
Delavirdinehsa04966Collecting duct acid secretion1.43E-043P02730, P00918, Q9Y666SLC4A1, CA2, SLC12A7More
Delavirdinehsa04970Salivary secretion6.64E-1112P07550, Q08828, P51828, P22694, Q14643, P20020, P23634, P17252, P0DP24, P0DP23, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B1, ATP2B4, PRKCA, CALM2, CALM1, GUCY1B3, CAMPMore
Delavirdinehsa04971Gastric acid secretion1.49E-086Q08828, P51828, P15311, P0DP24, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM2, CALM1, CAMK2DMore
Delavirdinehsa04972Pancreatic secretion1.00E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Delavirdinehsa04973Carbohydrate digestion and absorption4.61E-033O43451, P42338, P31751MGAM, PIK3CB, AKT2More
Delavirdinehsa04974Protein digestion and absorption1.22E-032Q7Z2H8, P02452SLC36A1, COL1A1More
Delavirdinehsa04975Fat digestion and absorption4.83E-021O14494PLPP1More
Delavirdinehsa04976Bile secretion1.97E-043Q08828, P51828, Q14032ADCY1, ADCY7, BAATMore
Delavirdinehsa04979Cholesterol metabolism1.37E-023P38571, P61916, P45880LIPA, NPC2, VDAC2More
Delavirdinehsa05010Alzheimer disease3.15E-1021P49768, Q92542, O15239, O95298, P19404, P05496, P13073, P12074, Q00535, O75460, P0DP23, P01584, Q12933, P18848, O15169, P67870, P31751, P05141, P45880, P28070, P43686PSEN1, NCSTN, NDUFA1, NDUFC2, NDUFV2, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, CALM1, IL1B, TRAF2, ATF4, AXIN1, CSNK2B, AKT2, SLC25A5, VDAC2, PSMB4, PSMC4More
Delavirdinehsa05012Parkinson disease9.83E-0519O15239, O95298, P13073, P12074, P05496, P05141, P12236, P21796, P60604, O75460, P18848, P28070, P43686, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, SLC25A5, SLC25A6, VDAC1, UBE2G2, ERN1, ATF4, PSMB4, PSMC4, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3More
Delavirdinehsa05014Amyotrophic lateral sclerosis6.58E-0315P01375, Q16718, P19404, O14521, P12074, P36542, O75460, P28070, Q8TEV9, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, NDUFV2, SDHD, COX6A1, ATP5C1, ERN1, PSMB4, SMCR8, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Delavirdinehsa05016Huntington disease4.22E-0815O95298, P19404, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, P05141, P45880, O75460, P28070, P55036, O00232NDUFC2, NDUFV2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, VDAC2, ERN1, PSMB4, PSMD4, PSMD12More
Delavirdinehsa05017Spinocerebellar ataxia1.88E-049Q92915, O75460, Q8TB72, O15399, P42338, P31751, P28070, P05141, P21796FGF14, ERN1, PUM2, GRIN2D, PIK3CB, AKT2, PSMB4, SLC25A5, VDAC1More
Delavirdinehsa05020Prion disease9.03E-0717P01584, P46531, P0DMV8, P11142, O15239, O95298, P05496, P13073, P12074, P18848, P05141, P12236, P45880, P28070, P43686, P67870, Q99941IL1B, NOTCH1, HSPA1A, HSPA8, NDUFA1, NDUFC2, ATP5G1, COX4I1, COX6A1, ATF4, SLC25A5, SLC25A6, VDAC2, PSMB4, PSMC4, CSNK2B, CREBL1More
Delavirdinehsa05022Pathways of neurodegeneration - multiple diseases1.42E-0826P67870, O15239, O95298, P19404, P13073, P12074, P05496, Q06055, Q8TEV9, O75460, P18848, Q12933, P05141, P45880, Q15078, Q00535, O15169, P01584, P49768, O15020, P0DP24, P0DP23, Q13557, P62987, P28070, P43686CSNK2B, NDUFA1, NDUFC2, NDUFV2, COX4I1, COX6A1, ATP5G1, ATP5G2, SMCR8, ERN1, ATF4, TRAF2, SLC25A5, VDAC2, CDK5R1, CDK5, AXIN1, IL1B, PSEN1, SPTBN2, CALM2, CALM1, CAMK2D, UBA52, PSMB4, PSMC4More
Delavirdinehsa05030Cocaine addiction5.99E-033Q00535, Q99941, P18848CDK5, CREBL1, ATF4More
Delavirdinehsa05031Amphetamine addiction4.45E-055P0DP24, P0DP23, Q13557, Q99941, P18848CALM2, CALM1, CAMK2D, CREBL1, ATF4More
Delavirdinehsa05032Morphine addiction4.50E-047P62873, P63218, P50151, Q13370, P78334, P32298, P43250GNB1, GNG5, GNG10, PDE3B, GABRE, GRK4, GRK6More
Delavirdinehsa05033Nicotine addiction4.01E-021P78334GABREMore
Delavirdinehsa05034Alcoholism1.46E-0717Q99941, P18848, Q13547, P0DP23, P0DP24, P62873, P63218, P50151, P61952, P04049, P0C0S5, Q93077, P62807, Q93079, Q16778, O60814, P68431CREBL1, ATF4, HDAC1, CALM1, CALM2, GNB1, GNG5, GNG10, GNG11, RAF1, H2AFZ, HIST1H2AC, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Delavirdinehsa05100Bacterial invasion of epithelial cells3.14E-033Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Delavirdinehsa05110Vibrio cholerae infection2.11E-032Q99437, P17612ATP6V0B, PRKACAMore
Delavirdinehsa05120Epithelial cell signaling in Helicobacter pylori infection2.10E-1210Q16539, Q99437, Q13153, P09341, P19875, P10145, P19174, P25024, P25025, P41240MAPK14, ATP6V0B, PAK1, CXCL1, CXCL2, IL8, PLCG1, CXCR1, CXCR2, CSKMore
Delavirdinehsa05130Pathogenic Escherichia coli infection1.02E-0413P16333, Q92974, Q13509, P60709, P63261, P25963, P04406, P29350, Q06124, Q15438, P35579, P55061, O95487NCK1, ARHGEF2, TUBB3, ACTB, ACTG1, NFKBIA, GAPDH, PTPN6, PTPN11, PSCD1, MYH9, TEGT, SEC24BMore
Delavirdinehsa05131Shigellosis2.79E-0514Q12933, Q13546, Q05655, Q02156, Q9UDY8, Q9NQL2, P0CG47, Q14141, Q96JJ3, Q05397, Q12778, Q13315, P10415, P07737TRAF2, RIPK1, PRKCD, PRKCE, MALT1, RRAGD, UBB, SEPT6, ELMO2, PTK2, FOXO1, ATM, BCL2, PFN1More
Delavirdinehsa05132Salmonella infection2.74E-1123P51617, P25963, P08238, P04049, Q9UJU2, P01106, P84095, P60709, P42338, Q13546, Q13489, P10415, P04406, O75369, P07737, O60603, Q9BQS8, P51808, Q13561, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, HSP90AB1, RAF1, LEF1, MYC, RHOG, ACTB, PIK3CB, RIPK1, BIRC3, BCL2, GAPDH, FLNB, PFN1, TLR2, FYCO1, DYNLT3, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Delavirdinehsa05133Pertussis1.42E-074P05107, P0DP23, P10145, P0C0L4ITGB2, CALM1, IL8, C4AMore
Delavirdinehsa05134Legionellosis1.05E-099P01584, P25963, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Delavirdinehsa05135Yersinia infection1.86E-048Q05397, P51812, P06239, P19174, Q02750, P42338, Q96JJ3, P01732PTK2, RPS6KA3, LCK, PLCG1, MAP2K1, PIK3CB, ELMO2, CD8AMore
Delavirdinehsa05140Leishmaniasis5.80E-1016P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Delavirdinehsa05142Chagas disease2.70E-022P48023, Q14790FASLG, CASP8More
Delavirdinehsa05143African trypanosomiasis7.11E-074P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Delavirdinehsa05144Malaria1.49E-0710P60033, P69905, P68871, O60603, P01375, P05107, P35443, P01584, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, ITGB2, THBS4, IL1B, IL8, KLRK1More
Delavirdinehsa05146Amoebiasis1.06E-1713P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Delavirdinehsa05150Staphylococcus aureus infection1.11E-0915P09871, P0C0L4, P21730, P21462, O75015, P31995, P13765, P13646, Q14532, P05107, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, FCGR2C, HLA-DOB, KRT13, KRT32, ITGB2, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Delavirdinehsa05152Tuberculosis1.04E-047P04049, P0DP23, P48382, P31751, P10415, Q9UDY8, P51617RAF1, CALM1, RFX5, AKT2, BCL2, MALT1, IRAK1More
Delavirdinehsa05160Hepatitis C1.31E-047Q13546, P01568, P60033, P04049, P49841, P01375, P48023RIPK1, IFNA21, CD81, RAF1, GSK3B, TNF, FASLGMore
Delavirdinehsa05161Hepatitis B4.32E-034P04049, Q99941, P18848, P27348RAF1, CREBL1, ATF4, YWHAQMore
Delavirdinehsa05162Measles3.90E-0513P01568, P25963, P23458, P42224, P14784, P07766, P42338, P31751, P0DMV8, P11142, P01584, P67870, Q9NP90IFNA21, NFKBIA, JAK1, STAT1, IL2RB, CD3E, PIK3CB, AKT2, HSPA1A, HSPA8, IL1B, CSNK2B, RAB9BMore
Delavirdinehsa05163Human cytomegalovirus infection5.97E-1331P31751, P42338, P04049, P01375, P25963, P62873, P63218, P50151, P61952, Q14643, P0DP23, P0DP24, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P01106, P14778, P01584, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P30101, P61769, P01568AKT2, PIK3CB, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, GNG11, ITPR1, CALM1, CALM2, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, MYC, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, PDIA3, B2M, IFNA21More
Delavirdinehsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Delavirdinehsa05165Human papillomavirus infection2.80E-0410P02452, P24821, Q16363, P30281, Q9UM47, P01568, P01889, P10321, Q99437, P04628COL1A1, TNC, LAMA4, CCND3, NOTCH3, IFNA21, HLA-B, HLA-C, ATP6V0B, WNT1More
Delavirdinehsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Delavirdinehsa05167Kaposi sarcoma-associated herpesvirus infection1.36E-0713P01568, P31751, P42224, P25963, P42338, P62873, P63218, P50151, P19174, P04049, P07948, P01106, P0DP23IFNA21, AKT2, STAT1, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, PLCG1, RAF1, LYN, MYC, CALM1More
Delavirdinehsa05168Herpes simplex virus 1 infection7.01E-0725O00463, O60603, P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q16629, Q13489, P30101, P42338, Q9Y2A4, Q13398, P51522, Q9NR11, Q9HCX3, P17097, P17038, Q03923, P52738, O75820, Q9UDV6, P10415TRAF5, TLR2, NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, SFRS7, BIRC3, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF302, ZNF304, ZNF7, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212, BCL2More
Delavirdinehsa05169Epstein-Barr virus infection1.15E-0924P13765, P01106, Q13547, Q92769, P04637, Q13546, O00463, P25963, P10415, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, P01375, O60603, P29728, P51617, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, HDAC2, TP53, RIPK1, TRAF5, NFKBIA, BCL2, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, TNF, TLR2, OAS2, IRAK1, CD3E, CD3G, CD247More
Delavirdinehsa05170Human immunodeficiency virus 1 infection7.71E-1025P31751, P42338, P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, Q05397, P17252, Q13546, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, P19174, P07766, P09693, P10415, Q9Y6Q5AKT2, PIK3CB, RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, PTK2, PRKCA, RIPK1, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, PLCG1, CD3E, CD3G, BCL2, AP1M2More
Delavirdinehsa05171Coronavirus disease - COVID-193.96E-0917P23396, P62753, P25398, P42677, P36578, Q02878, P62917, P32969, P27635, P26373, Q07020, P46776, P62899, P62910, P18077, P61927, P05386RPS3, RPS6, RPS12, RPS27, RPL4, RPL6, RPL8, RPL9, RPL10, RPL13, RPL18, RPL27A, RPL31, RPL32, RPL35A, RPL37, RPLP1More
Delavirdinehsa05200Pathways in cancer4.07E-0931P42338, P08238, P42224, P25963, P19174, P01106, Q9UJU2, P43246, Q13485, P20585, P52701, Q13547, P14923, P30279, P10415, Q13077, P49767, P14921, P31751, P62873, P63218, P50151, Q14344, Q9UM47, P78417, O75293, P0DP23, P01568, P14784, P40189, P01042PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, LEF1, MSH2, SMAD4, MSH3, MSH6, HDAC1, JUP, CCND2, BCL2, TRAF1, VEGFC, ETS1, AKT2, GNB1, GNG5, GNG10, GNA13, NOTCH3, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6ST, KNG1More
Delavirdinehsa05202Transcriptional misregulation in cancer2.59E-0921Q12778, Q13315, P41732, P17844, P14780, P27930, Q15744, Q16548, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, ATM, TSPAN7, DDX5, MMP9, IL1R2, CEBPE, BCL2A1, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Delavirdinehsa05203Viral carcinogenesis1.04E-0721Q12933, Q99941, P18848, P42338, P06746, P07948, P30281, P27348, P29083, Q13547, Q15283, P06396, P12814, P25963, P01889, P10321, P06493, P62807, Q93079, Q16778, O60814TRAF2, CREBL1, ATF4, PIK3CB, POLB, LYN, CCND3, YWHAQ, GTF2E1, HDAC1, RASA2, GSN, ACTN1, NFKBIA, HLA-B, HLA-C, CDK1, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12More
Delavirdinehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Delavirdinehsa05205Proteoglycans in cancer6.79E-0510Q13009, Q12955, O75369, P60709, P04049, P01106, P08069, P19174, P29350, P08962TIAM1, ANK3, FLNB, ACTB, RAF1, MYC, IGF1R, PLCG1, PTPN6, CD63More
Delavirdinehsa05206MicroRNAs in cancer1.17E-0414P30304, P09493, P15311, P21860, P01106, P42338, P61978, P46531, Q13547, P63279, P22105, P20827, P19174, P04049CDC25A, TPM1, VIL2, ERBB3, MYC, PIK3CB, HNRPK, NOTCH1, HDAC1, UBE2I, TNXB, EFNA1, PLCG1, RAF1More
Delavirdinehsa05210Colorectal cancer1.47E-049Q9UKG1, Q13485, P43246, P04049, P01106, P52701, P20585, P37173, O75293APPL1, SMAD4, MSH2, RAF1, MYC, MSH6, MSH3, TGFBR2, GADD45BMore
Delavirdinehsa05211Renal cell carcinoma1.84E-055Q06124, Q99814, Q13153, P31751, P04049PTPN11, EPAS1, PAK1, AKT2, RAF1More
Delavirdinehsa05212Pancreatic cancer3.26E-057P42338, P31751, P04049, Q15311, P23458, P42224, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, GADD45BMore
Delavirdinehsa05213Endometrial cancer8.16E-042P31751, P04049AKT2, RAF1More
Delavirdinehsa05214Glioma1.12E-0910P08069, P0DP23, P17252, P04049, P42338, P31751, P04637, P19174, P24522, O75293IGF1R, CALM1, PRKCA, RAF1, PIK3CB, AKT2, TP53, PLCG1, GADD45A, GADD45BMore
Delavirdinehsa05215Prostate cancer2.34E-045P10415, Q12778, P08069, Q9NRA1, P04049BCL2, FOXO1, IGF1R, PDGFC, RAF1More
Delavirdinehsa05216Thyroid cancer1.58E-035P01106, Q9UJU2, P04637, P24522, O75293MYC, LEF1, TP53, GADD45A, GADD45BMore
Delavirdinehsa05217Basal cell carcinoma9.05E-046Q13635, P04628, P49841, Q9UJU2, P04637, P24522PTCH1, WNT1, GSK3B, LEF1, TP53, GADD45AMore
Delavirdinehsa05218Melanoma3.78E-056P08069, Q9NRA1, P31751, P42338, P04049, O75293IGF1R, PDGFC, AKT2, PIK3CB, RAF1, GADD45BMore
Delavirdinehsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Delavirdinehsa05220Chronic myeloid leukemia2.10E-047Q13547, P01106, P25963, P31751, P42338, P04049, O75293HDAC1, MYC, NFKBIA, AKT2, PIK3CB, RAF1, GADD45BMore
Delavirdinehsa05221Acute myeloid leukemia8.73E-045P31751, P42338, P04049, Q15744, P11215AKT2, PIK3CB, RAF1, CEBPE, ITGAMMore
Delavirdinehsa05222Small cell lung cancer4.78E-021P31751AKT2More
Delavirdinehsa05223Non-small cell lung cancer3.89E-055P31751, P10826, P04049, Q9HC35, O75293AKT2, RARB, RAF1, EML4, GADD45BMore
Delavirdinehsa05224Breast cancer2.75E-036P04049, P08069, P49841, Q92837, P04637, P24522RAF1, IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Delavirdinehsa05225Hepatocellular carcinoma1.65E-042P04049, P08069RAF1, IGF1RMore
Delavirdinehsa05226Gastric cancer6.81E-042P04049, P31751RAF1, AKT2More
Delavirdinehsa05230Central carbon metabolism in cancer1.12E-032P04049, P31751RAF1, AKT2More
Delavirdinehsa05231Choline metabolism in cancer2.98E-0811P04049, P31751, P42338, Q9NRA1, Q9Y259, P19174, P23743, P49619, Q16760, O14986, O14494RAF1, AKT2, PIK3CB, PDGFC, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PLPP1More
Delavirdinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer5.27E-1818P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P04049, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, RAF1, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Delavirdinehsa05310Asthma7.64E-083P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Delavirdinehsa05321Inflammatory bowel disease1.41E-148O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Delavirdinehsa05322Systemic lupus erythematosus1.44E-0715P08637, O75015, P08246, P08311, P09871, P01375, P10747, P13765, Q93077, P62807, Q16778, O60814, P68431, P14678, P12814FCGR3A, FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SNRPB, ACTN1More
Delavirdinehsa05323Rheumatoid arthritis1.89E-047P01375, Q06643, P13765, P10747, P09341, P19875, O60603TNF, LTB, HLA-DOB, CD28, CXCL1, CXCL2, TLR2More
Delavirdinehsa05330Allograft rejection2.02E-034P13765, P48023, P10747, P01375HLA-DOB, FASLG, CD28, TNFMore
Delavirdinehsa05332Graft-versus-host disease4.96E-126P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Delavirdinehsa05340Primary immunodeficiency2.12E-066P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Delavirdinehsa05410Hypertrophic cardiomyopathy3.63E-022P26012, P09493ITGB8, TPM1More
Delavirdinehsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Delavirdinehsa05414Dilated cardiomyopathy3.78E-034P54284, P26012, P09493, P26678CACNB3, ITGB8, TPM1, PLNMore
Delavirdinehsa05415Diabetic cardiomyopathy1.49E-0410P17252, P30405, P14598, Q15080, Q16718, O14521, Q16539, P14780, P37173, P04406PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, MAPK14, MMP9, TGFBR2, GAPDHMore
Delavirdinehsa05418Fluid shear stress and atherosclerosis1.25E-0713Q16539, P31751, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, AKT2, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Delavirdine (SDC: 12.36)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P40925MDH1Malate dehydrogenase, cytoplasmicPredicted00.35660.27460.24260.97
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P30530AXLTyrosineNoneprotein kinase receptor UFOPredicted10.37970.53650.16371.4264
P51684CCR6CNoneC chemokine receptor type 6Predicted00.0850.17410.33040.7212
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P31751AKT2RACNonebeta serine/threonineNoneprotein kinasePredicted00.46620.485612.2044
Q8IVH8MAP4K3MitogenNoneactivated protein kinase kinase kinase kinase 3Predicted00.38330.26730.14870.875
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
P09769FGRTyrosineNoneprotein kinase FgrPredicted00.06220.32440.2250.9049
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
O14976GAKCyclinNoneGNoneassociated kinasePredicted10.57280.256200.7989
Q00536PCTK1CyclinNonedependent kinase 16Predicted00.27140.25600.6478
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q2M2I8AAK1AP2Noneassociated protein kinase 1Predicted10.37690.328800.846
P51955NEK2Serine/threonineNoneprotein kinase Nek2Predicted00.65990.369201.0684
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
P45985MAP2K4Dual specificity mitogenNoneactivated protein kinase kinase 4Predicted00.42480.24730.74031.4474
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
P24723PRKCHProtein kinase C eta typePredicted00.19550.32940.20480.9614
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
Q9Y6R4MAP3K4MitogenNoneactivated protein kinase kinase kinase 4Predicted00.35280.24520.1730.8399
Q9UEE5STK17ASerine/threonineNoneprotein kinase 17APredicted00.35040.337600.8504
Q15418RPS6KA1Ribosomal protein S6 kinase alphaNone1Predicted10.8320.32450.41461.4796
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
Q15831STK11Serine/threonineNoneprotein kinase STK11Predicted00.15110.24410.45491.0186
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q07912TNK2Activated CDC42 kinase 1Predicted00.0090.347200.6988
Q8IVW4CDKL3CyclinNonedependent kinaseNonelike 3Predicted00.41490.241600.6906
Q13873BMPR2Bone morphogenetic protein receptor typeNone2Predicted10.34760.24520.35481.019
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
O75460ERN1Serine/threonineNoneprotein kinase/endoribonuclease IRE1Predicted10.68060.29440.5571.4862
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
Q9Y6E0STK24Serine/threonineNoneprotein kinase 24Predicted00.54580.245200.7634
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
P51617IRAK1InterleukinNone1 receptorNoneassociated kinase 1Predicted00.02380.30.94441.5563
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
Q16566CAMK4Calcium/calmodulinNonedependent protein kinase type IVPredicted00.07180.24410.61761.1417
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
P21860ERBB3Receptor tyrosineNoneprotein kinase erbBNone3Predicted00.1260.27290.47881.0876
P07332FESTyrosineNoneprotein kinase Fes/FpsPredicted00.27220.26280.15130.8131
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P07948LYNTyrosineNoneprotein kinase LynPredicted00.0910.53190.6061.7154
Q99759MAP3K3MitogenNoneactivated protein kinase kinase kinase 3Predicted00.35450.24520.43781.1055
Q13153PAK1Serine/threonineNoneprotein kinase PAK 1Predicted10.46470.34710.78191.7084
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
P22694PRKACBcAMPNonedependent protein kinase catalytic subunit betaPredicted00.37370.298411.7836
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
Q13523PRPF4BSerine/threonineNoneprotein kinase PRP4 homologPredicted00.13760.245200.5593
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
O43318MAP3K7MitogenNoneactivated protein kinase kinase kinase 7Predicted00.00590.364911.7327
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
P32298GRK4G proteinNonecoupled receptor kinase 4Predicted00.03520.23860.29480.7896
P41240CSKTyrosineNoneprotein kinase CSKPredicted00.69860.36260.10231.1768
Q9H2K8TAOK3Serine/threonineNoneprotein kinase TAO3Predicted00.06460.24520.14870.6715
Q9P289STK26Serine/threonineNoneprotein kinase 26Predicted10.02850.262800.5399
Q9NQU5PAK6Serine/threonineNoneprotein kinase PAK 6Predicted00.4090.26690.50031.2386
Q8NI60CABC1Atypical kinase COQ8A, mitochondrialPredicted00.62760.245200.8043
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
O95835LATS1Serine/threonineNoneprotein kinase LATS1Predicted00.43320.24520.02170.7288
O43283MAP3K13MitogenNoneactivated protein kinase kinase kinase 13Predicted00.45650.24520.14870.8674
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P51817PRKXcAMPNonedependent protein kinase catalytic subunit PRKXPredicted00.40630.276500.7562
O95747OXSR1Serine/threonineNoneprotein kinase OSR1Predicted00.18390.245200.5825
Q02156PRKCEProtein kinase C epsilon typePredicted00.11750.52870.53771.6539
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q9H422HIPK3HomeodomainNoneinteracting protein kinase 3Predicted00.3650.25080.2180.902
O94806PRKD3Serine/threonineNoneprotein kinase D3Predicted00.23120.24340.16920.7715
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
Q16513PKN2Serine/threonineNoneprotein kinase N2Predicted00.04210.27780.33910.9157
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
Q9UEW8STK39STE20/SPS1Nonerelated prolineNonealanineNonerich protein kinasePredicted00.25730.245200.6191
Q96BR1SGK3Serine/threonineNoneprotein kinase Sgk3Predicted00.0260.26840.31140.8612
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
Q06124PTPN11TyrosineNoneprotein phosphatase nonNonereceptor type 11Predicted10.15130.45660.6131.6017
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P98170BIRC4E3 ubiquitinNoneprotein ligase XIAPPredicted00.29740.22980.791.3984
Q13822ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Predicted00.1130.3050.00630.6729
P41182BCL6BNonecell lymphoma 6 proteinPredicted10.08070.03410.380.4885
P00734F2ProthrombinPredicted10.09630.7070.49771.9598
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)