PharmaCoNets of Dasatinib (SPCN: 245.60 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Dasatinibhsa00010Glycolysis / Gluconeogenesis1.89E-035P04075, P14550, P11766, P07195, P60174ALDOA, AKR1A1, ADH5, LDHB, TPI1More
Dasatinibhsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Dasatinibhsa00030Pentose phosphate pathway2.93E-104P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Dasatinibhsa00040Pentose and glucuronate interconversions4.08E-053P15121, O60701, P14550AKR1B1, UGDH, AKR1A1More
Dasatinibhsa00051Fructose and mannose metabolism2.63E-055P15121, P19367, P08237, P60174, P04075AKR1B1, HK1, PFKM, TPI1, ALDOAMore
Dasatinibhsa00052Galactose metabolism4.25E-056P06280, P08237, O43451, P15121, P19367, Q14376GLA, PFKM, MGAM, AKR1B1, HK1, GALEMore
Dasatinibhsa00071Fatty acid degradation2.38E-023P11310, O75521, P33121ACADM, ECI2, ACSL1More
Dasatinibhsa00100Steroid biosynthesis3.94E-021P35610SOAT1More
Dasatinibhsa00190Oxidative phosphorylation7.86E-053Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Dasatinibhsa00220Arginine biosynthesis1.21E-063P15104, P05089, P49448GLUL, ARG1, GLUD2More
Dasatinibhsa00230Purine metabolism3.35E-022Q7LG56, P51828RRM2B, ADCY7More
Dasatinibhsa00250Alanine, aspartate and glutamate metabolism6.84E-053Q96RQ9, P49448, P15104IL4I1, GLUD2, GLULMore
Dasatinibhsa00270Cysteine and methionine metabolism2.39E-022Q96RQ9, P40926IL4I1, MDH2More
Dasatinibhsa00280Valine, leucine and isoleucine degradation1.93E-046P55809, Q9HCC0, Q96RQ9, P05166, Q02252, P11310OXCT1, MCCC2, IL4I1, PCCB, ALDH6A1, ACADMMore
Dasatinibhsa00310Lysine degradation2.14E-057Q9NVH6, Q96KQ7, Q8NEZ4, Q13029, O15047, Q02809, P51648TMLHE, EHMT2, MLL3, PRDM2, SETD1A, PLOD1, ALDH3A2More
Dasatinibhsa00330Arginine and proline metabolism2.73E-021P17707AMD1More
Dasatinibhsa00350Tyrosine metabolism4.50E-021P00325ADH1BMore
Dasatinibhsa00380Tryptophan metabolism3.02E-021Q16613AANATMore
Dasatinibhsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Dasatinibhsa00471D-Glutamine and D-glutamate metabolism1.54E-032Q7Z3D6, P49448C14orf159, GLUD2More
Dasatinibhsa00500Starch and sucrose metabolism3.15E-084O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Dasatinibhsa00510N-Glycan biosynthesis1.10E-034O94777, P15907, Q9BVK2, Q9NR34DPM2, ST6GAL1, ALG8, MAN1C1More
Dasatinibhsa00513Various types of N-glycan biosynthesis4.83E-021Q9NR34MAN1C1More
Dasatinibhsa00520Amino sugar and nucleotide sugar metabolism2.98E-053Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Dasatinibhsa00531Glycosaminoglycan degradation3.78E-021P15586GNSMore
Dasatinibhsa00561Glycerolipid metabolism8.93E-033P15121, P14550, Q86XP1AKR1B1, AKR1A1, DGKHMore
Dasatinibhsa00562Inositol phosphate metabolism4.54E-045Q9NRR6, P27987, O14732, P19174, P42338INPP5E, ITPKB, IMPA2, PLCG1, PIK3CBMore
Dasatinibhsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.28E-032O94777, Q14442DPM2, PIGHMore
Dasatinibhsa00564Glycerophospholipid metabolism1.37E-068P48651, Q9Y6K0, P35790, Q9Y259, P23743, P49619, O14494, Q3LIE5PTDSS1, CEPT1, CHKA, CHKB, DGKA, DGKG, PLPP1, ADPRMMore
Dasatinibhsa00565Ether lipid metabolism1.04E-022Q9Y6K0, Q8N661CEPT1, TMEM86BMore
Dasatinibhsa00590Arachidonic acid metabolism2.97E-021P09917ALOX5More
Dasatinibhsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Dasatinibhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.27E-072P06865, O75752HEXA, B3GALNT1More
Dasatinibhsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Dasatinibhsa00620Pyruvate metabolism9.80E-044P40926, P07195, P14550, P11766MDH2, LDHB, AKR1A1, ADH5More
Dasatinibhsa00630Glyoxylate and dicarboxylate metabolism4.66E-124P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Dasatinibhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Dasatinibhsa00670One carbon pool by folate1.09E-063O95954, P04818, Q99707FTCD, TYMS, MTRMore
Dasatinibhsa00730Thiamine metabolism1.55E-032P05186, P24666ALPL, ACP1More
Dasatinibhsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Dasatinibhsa00750Vitamin B6 metabolism4.45E-021O00764PDXKMore
Dasatinibhsa00770Pantothenate and CoA biosynthesis2.82E-053O95498, Q6ZQY3, Q9NRN7VNN2, GADL1, AASDHPPTMore
Dasatinibhsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Dasatinibhsa00790Folate biosynthesis6.55E-044Q92820, P05186, P15121, P42330GGH, ALPL, AKR1B1, AKR1C3More
Dasatinibhsa00830Retinol metabolism1.76E-055P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Dasatinibhsa00860Porphyrin and chlorophyll metabolism1.53E-043P36551, P53004, P30043CPOX, BLVRA, BLVRBMore
Dasatinibhsa00900Terpenoid backbone biosynthesis4.22E-022P49354, Q9UHG3FNTA, PCYOX1More
Dasatinibhsa00910Nitrogen metabolism4.40E-032P15104, P49448GLUL, GLUD2More
Dasatinibhsa00970Aminoacyl-tRNA biosynthesis2.84E-034O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Dasatinibhsa00983Drug metabolism - other enzymes1.07E-065P04183, P20839, P32320, P05164, Q16772TK1, IMPDH1, CDA, MPO, GSTA3More
Dasatinibhsa01040Biosynthesis of unsaturated fatty acids4.28E-021P22307SCP2More
Dasatinibhsa01100Metabolic pathways6.82E-0870Q9NR34, Q9Y234, P35790, P05089, P21953, Q16772, Q9UJ14, P30041, P15104, P19367, P42338, Q9Y217, P48426, P27987, Q96DU7, P22557, Q6ZQY3, P32320, Q08828, Q02153, P20839, P22748, P40926, P55809, P06280, O94777, Q16875, O43286, O43451, P53004, Q9Y6K0, P05186, P24666, P15121, P08237, Q86XP1, O95861, Q96RQ9, P14550, Q9HCC0, P33121, Q9UHK6, Q86VZ5, Q96G23, P09917, P48651, Q9BVK2, P57054, Q14442, Q9UNP4, Q9H4F1, Q9BX95, Q9BRR6, P32321, P49448, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q969G6, P05166, P14927, P12074, P05496, Q99437, O15239, O15047, Q9NVH6MAN1C1, LIPT1, CHKA, ARG1, BCKDHB, GSTA3, GGTL3, PRDX6, GLUL, HK1, PIK3CB, MTMR6, PIP4K2A, ITPKB, ITPKC, ALAS2, GADL1, CDA, ADCY1, GUCY1B3, IMPDH1, CA4, MDH2, OXCT1, GLA, DPM2, PFKFB3, B4GALT5, MGAM, BLVRA, CEPT1, ALPL, ACP1, AKR1B1, PFKM, DGKH, BPNT1, IL4I1, AKR1A1, MCCC2, ACSL1, AMACR, SGMS1, LASS2, ALOX5, PTDSS1, ALG8, PIGP, PIGH, ST3GAL5, ST6GALNAC4, SGPP1, ADPGK, DCTD, GLUD2, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, RFK, PCCB, UQCRB, COX6A1, ATP5G1, ATP6V0B, NDUFA1, SETD1A, TMLHEMore
Dasatinibhsa01200Carbon metabolism2.13E-022P52209, P37837PGD, TALDO1More
Dasatinibhsa01212Fatty acid metabolism4.62E-022P33121, P11310ACSL1, ACADMMore
Dasatinibhsa01230Biosynthesis of amino acids1.89E-046P51854, P60891, Q99707, P50213, P05089, P37837TKTL1, PRPS1, MTR, IDH3A, ARG1, TALDO1More
Dasatinibhsa01240Biosynthesis of cofactors3.32E-057Q969G6, P13716, P36551, P22557, O60701, P14618, Q9Y234RFK, ALAD, CPOX, ALAS2, UGDH, PKM2, LIPT1More
Dasatinibhsa01521EGFR tyrosine kinase inhibitor resistance3.18E-042P04049, P08069RAF1, IGF1RMore
Dasatinibhsa01522Endocrine resistance1.02E-047P04049, Q9UM47, P04637, P42773, P08069, P10415, Q13323RAF1, NOTCH3, TP53, CDKN2C, IGF1R, BCL2, BIKMore
Dasatinibhsa01523Antifolate resistance2.08E-044P41440, Q92820, P04818, P01375SLC19A1, GGH, TYMS, TNFMore
Dasatinibhsa01524Platinum drug resistance2.37E-058Q13489, Q14790, P48023, P78417, P40692, P23025, P52701, P31751BIRC3, CASP8, FASLG, GSTO1, MLH1, XPA, MSH6, AKT2More
Dasatinibhsa02010ABC transporters4.48E-021Q8IZY2ABCA7More
Dasatinibhsa03010Ribosome9.17E-2123P26373, P62753, P42677, P25398, P32969, P40429, P62917, P46776, Q9H0U6, Q07020, P46778, P62945, P62899, P62910, P18077, P61927, P61513, Q02878, P36578, P27635, P05386, P62249, P23396RPL13, RPS6, RPS27, RPS12, RPL9, RPL13A, RPL8, RPL27A, MRPL18, RPL18, RPL21, RPL41, RPL31, RPL32, RPL35A, RPL37, RPL37A, RPL6, RPL4, RPL10, RPLP1, RPS16, RPS3More
Dasatinibhsa03013RNA transport5.82E-2129P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9H307, Q7Z3B4, P35658, P63279, P68104, P47813, O14602, Q14152, P55884, O15371, O75822, P78345, Q9H777, P11940, P20042, Q14240, Q9BZI7, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF1AY, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, ELAC1, PABPC1, EIF2S2, EIF4A2, UPF3B, TACC3, EIF2B1, FMR1, FXR1More
Dasatinibhsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Dasatinibhsa03020RNA polymerase7.29E-084P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Dasatinibhsa03022Basal transcription factors3.52E-033O00268, Q5H9L4, Q15544TAF4, TAF7L, TAF11More
Dasatinibhsa03040Spliceosome1.54E-1216Q14562, O43143, O60508, P08579, P26368, O75940, O75494, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, SMNDC1, FUSIP1, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Dasatinibhsa03060Protein export3.67E-094Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Dasatinibhsa03320PPAR signaling pathway4.33E-022Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Dasatinibhsa03410Base excision repair2.21E-022P49005, P29372POLD2, MPGMore
Dasatinibhsa03430Mismatch repair4.38E-021P20585MSH3More
Dasatinibhsa03450Non-homologous end-joining4.32E-021Q9NP87POLMMore
Dasatinibhsa03460Fanconi anemia pathway8.90E-043P40692, O60673, Q9UNA4MLH1, REV3L, POLIMore
Dasatinibhsa04010MAPK signaling pathway8.69E-054P04049, P08069, Q9H2K8, Q12933RAF1, IGF1R, TAOK3, TRAF2More
Dasatinibhsa04012ErbB signaling pathway3.61E-057Q13153, P16333, Q13191, P19174, P42338, P01106, P04049PAK1, NCK1, CBLB, PLCG1, PIK3CB, MYC, RAF1More
Dasatinibhsa04014Ras signaling pathway6.08E-049P04049, P31751, P20827, P49767, P08069, P17252, P0DP23, P62873, P19174RAF1, AKT2, EFNA1, VEGFC, IGF1R, PRKCA, CALM1, GNB1, PLCG1More
Dasatinibhsa04015Rap1 signaling pathway1.56E-0511P04049, P20827, P49767, P08069, P06213, P11215, O00522, P31751, P0DP23, P17252, P19174RAF1, EFNA1, VEGFC, IGF1R, INSR, ITGAM, KRIT1, AKT2, CALM1, PRKCA, PLCG1More
Dasatinibhsa04020Calcium signaling pathway1.96E-0816P27987, Q96DU7, Q08828, P21796, P45880, Q13557, P17252, P21860, P30679, P19174, P0DP23, P0DP24, P05141, P51828, P23634, P49767ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK2D, PRKCA, ERBB3, GNA15, PLCG1, CALM1, CALM2, SLC25A5, ADCY7, ATP2B4, VEGFCMore
Dasatinibhsa04022cGMP-PKG signaling pathway1.20E-0915Q02153, Q14814, P04049, Q99941, P18848, P23634, P31751, Q08828, P51828, P05141, P21796, P45880, P0DP23, P0DP24, P01042GUCY1B3, MEF2D, RAF1, CREBL1, ATF4, ATP2B4, AKT2, ADCY1, ADCY7, SLC25A5, VDAC1, VDAC2, CALM1, CALM2, KNG1More
Dasatinibhsa04024cAMP signaling pathway2.01E-059Q08828, P51828, P42338, P31751, P0DP23, P04049, Q13370, Q13009, Q13153ADCY1, ADCY7, PIK3CB, AKT2, CALM1, RAF1, PDE3B, TIAM1, PAK1More
Dasatinibhsa04060Cytokine-cytokine receptor interaction3.18E-0721P14784, P27930, P14778, P37173, P08476, P26842, Q06643, Q13651, Q9HBE5, P78552, P25024, P25025, Q9UBD3, P47992, P01375, P09341, P19875, P80075, P18510, P01730, Q93038IL2RB, IL1R2, IL1R1, TGFBR2, INHBA, CD27, LTB, IL10RA, IL21R, IL13RA1, CXCR1, CXCR2, XCL2, XCL1, TNF, CXCL1, CXCL2, CCL8, IL1RN, CD4, TNFRSF25More
Dasatinibhsa04061Viral protein interaction with cytokine and cytokine receptor1.49E-079Q8NHW4, P09341, P25024, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Dasatinibhsa04062Chemokine signaling pathway1.43E-0719P25024, P25025, P09341, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q13009, P14598, P42224, P04049, P25963CXCR1, CXCR2, CXCL1, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, TIAM1, NCF1, STAT1, RAF1, NFKBIAMore
Dasatinibhsa04064NF-kappa B signaling pathway1.72E-1625P10415, Q13489, P51617, O00463, Q13546, P14778, P01584, P01375, P29965, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, CD40LG, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Dasatinibhsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Dasatinibhsa04068FoxO signaling pathway4.41E-054P04049, P08069, P48023, Q96BR1RAF1, IGF1R, FASLG, SGK3More
Dasatinibhsa04070Phosphatidylinositol signaling system2.18E-1013P19174, P0DP23, Q14643, P42338, O14986, P23743, P49619, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIK3CB, PIP5K1B, DGKA, DGKG, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Dasatinibhsa04071Sphingolipid signaling pathway2.63E-0714P04049, P17252, P21453, Q9H228, P01375, Q96G23, Q13510, Q13362, Q9BX95, Q16539, P10415, Q9UQC2, Q12933, Q02156RAF1, PRKCA, S1PR1, EDG8, TNF, LASS2, ASAH1, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2, TRAF2, PRKCEMore
Dasatinibhsa04072Phospholipase D signaling pathway1.84E-068P04049, P31751, Q9UQC2, O14986, Q15438, Q08828, P51828, Q16760RAF1, AKT2, GAB2, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKDMore
Dasatinibhsa04080Neuroactive ligand-receptor interaction6.55E-0713P08311, P28472, P78334, Q15722, P21453, Q9H228, P43657, P21462, P21730, P30939, P14416, P07550, P35318CTSG, GABRB3, GABRE, LTB4R, S1PR1, EDG8, P2RY5, FPR1, C5AR1, HTR1F, DRD2, ADRB2, ADMMore
Dasatinibhsa04110Cell cycle4.62E-0712Q9UBD5, P30260, P06493, O60566, Q14683, P04637, P49918, P30304, P33981, P42773, P01106, Q13547ORC3, CDC27, CDK1, BUB1B, SMC1A, TP53, CDKN1C, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Dasatinibhsa04114Oocyte meiosis5.73E-1011Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Dasatinibhsa04115p53 signaling pathway2.54E-023O15151, Q13315, P10415MDM4, ATM, BCL2More
Dasatinibhsa04120Ubiquitin mediated proteolysis1.08E-036Q9UBT2, Q14145, Q13042, P62837, Q15751, Q14669SAE2, KEAP1, CDC16, UBE2D2, HERC1, TRIP12More
Dasatinibhsa04130SNARE interactions in vesicular transport1.52E-021P23763VAMP1More
Dasatinibhsa04136Autophagy - other7.59E-032O94817, Q9H1Y0ATG12, ATG5More
Dasatinibhsa04137Mitophagy - animal1.41E-033P67870, P19532, P18848CSNK2B, TFE3, ATF4More
Dasatinibhsa04140Autophagy - animal3.90E-0515P08069, Q9Y4H2, P42338, P31751, P04049, Q7L523, Q9NQL2, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, IRS2, PIK3CB, AKT2, RAF1, RRAGA, RRAGD, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Dasatinibhsa04141Protein processing in endoplasmic reticulum2.47E-0613P18848, Q12933, P30101, Q15437, Q15436, P60604, Q99941, P11142, Q9H3Z4, P07900, P08238, Q9NR31, Q9UNL2ATF4, TRAF2, PDIA3, SEC23B, SEC23A, UBE2G2, CREBL1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, SSR3More
Dasatinibhsa04142Lysosome1.11E-0511O14773, P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, Q9NRA2, P49279, P61916, Q04900TPP1, HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC17A5, SLC11A1, NPC2, CD164More
Dasatinibhsa04144Endocytosis2.34E-0719Q13191, P0DMV8, P11142, Q9H444, O43633, O75351, P62491, P25024, Q96B97, P43250, Q6WKZ4, Q15438, Q8WU79, Q14161, P14784, O95219, O75154, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, CHMP2A, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, RAB11FIP1, PSCD1, SMAP1L, GIT2, IL2RB, SNX4, RAB11FIP3, SNX12, SNX5More
Dasatinibhsa04145Phagosome4.29E-0611O75015, Q15080, P14598, Q13509, P68371, Q13488, P05164, P78380, O60603, P35443, P13765FCGR3B, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Dasatinibhsa04146Peroxisome1.43E-024O00623, P56589, Q9UKG9, P33121PEX12, PEX3, CROT, ACSL1More
Dasatinibhsa04150mTOR signaling pathway5.20E-042P08069, P04049IGF1R, RAF1More
Dasatinibhsa04151PI3K-Akt signaling pathway1.46E-0831P62753, P21860, P25116, O43521, P04637, P27348, P49767, Q13362, P07900, P08238, P62873, P63218, P61952, P16144, P02452, P24821, Q16363, P22105, O60603, P14784, P23458, P01568, Q99941, P18848, P10415, P17252, Q96BR1, O00141, Q6ZUJ8, P30279, P56279RPS6, ERBB3, F2R, BCL2L11, TP53, YWHAQ, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, GNB1, GNG5, GNG11, ITGB4, COL1A1, TNC, LAMA4, TNXB, TLR2, IL2RB, JAK1, IFNA21, CREBL1, ATF4, BCL2, PRKCA, SGK3, SGK, PIK3AP1, CCND2, TCL1AMore
Dasatinibhsa04152AMPK signaling pathway3.64E-033P08069, Q96RR4, Q13362IGF1R, CAMKK2, PPP2R5CMore
Dasatinibhsa04210Apoptosis1.10E-034Q14790, P48023, P42575, P04049CASP8, FASLG, CASP2, RAF1More
Dasatinibhsa04211Longevity regulating pathway3.00E-056P31751, P08069, Q08828, P51828, P18848, Q96RR4AKT2, IGF1R, ADCY1, ADCY7, ATF4, CAMKK2More
Dasatinibhsa04213Longevity regulating pathway - multiple species2.05E-099P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Dasatinibhsa04217Necroptosis9.83E-1428P01375, Q12933, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P42229, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q9BTM1, Q6FI13, Q99878, P10415, Q13557, Q9H444, O43633, O75351, P21796, P45880, Q08752TNF, TRAF2, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, STAT5A, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AFJ, H2AC18; H2AC19, H2AC14, BCL2, CAMK2D, CHMP4B, CHMP2A, VPS4B, VDAC1, VDAC2, PPIDMore
Dasatinibhsa04218Cellular senescence1.96E-047P31751, P04049, P30281, P0DP23, P01889, P10321, P12236AKT2, RAF1, CCND3, CALM1, HLA-B, HLA-C, SLC25A6More
Dasatinibhsa04260Cardiac muscle contraction4.20E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Dasatinibhsa04261Adrenergic signaling in cardiomyocytes6.80E-0915P09493, P67936, Q08828, P51828, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, P0DP24, Q13557, P17252, P10415, P23634TPM1, TPM4, ADCY1, ADCY7, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CALM2, CAMK2D, PRKCA, BCL2, ATP2B4More
Dasatinibhsa04270Vascular smooth muscle contraction1.84E-0711P24723, Q04759, Q14643, P0DP23, P04049, Q08828, P51828, P22694, P35579, P35749, P35318PRKCH, PRKCQ, ITPR1, CALM1, RAF1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Dasatinibhsa04310Wnt signaling pathway2.28E-045P30279, Q13485, O43318, P17612, P67870CCND2, SMAD4, MAP3K7, PRKACA, CSNK2BMore
Dasatinibhsa04330Notch signaling pathway4.54E-044Q92542, P49768, P46531, Q9UM47NCSTN, PSEN1, NOTCH1, NOTCH3More
Dasatinibhsa04340Hedgehog signaling pathway2.00E-045P49841, P17612, P22694, Q13635, P10415GSK3B, PRKACA, PRKACB, PTCH1, BCL2More
Dasatinibhsa04360Axon guidance2.39E-0613P16298, Q05397, P16333, P20827, O95631, P17252, Q13873, P42338, P23528, P04049, P19174, O14639, P24844PPP3CB, PTK2, NCK1, EFNA1, NTN1, PRKCA, BMPR2, PIK3CB, CFL1, RAF1, PLCG1, ABLIM1, MYL9More
Dasatinibhsa04370VEGF signaling pathway6.18E-137P19174, P16298, P31751, P42338, Q05397, Q02750, P04049PLCG1, PPP3CB, AKT2, PIK3CB, PTK2, MAP2K1, RAF1More
Dasatinibhsa04371Apelin signaling pathway1.43E-049P62873, P61952, P31751, P04049, Q08828, P51828, P62753, P0DP23, P0DP24GNB1, GNG11, AKT2, RAF1, ADCY1, ADCY7, RPS6, CALM1, CALM2More
Dasatinibhsa04380Osteoclast differentiation5.02E-0910Q9NQC7, Q9UQC2, Q16539, P23458, P31751, P01584, P14778, O75015, P01375, Q8N149CYLD, GAB2, MAPK14, JAK1, AKT2, IL1B, IL1R1, FCGR3B, TNF, LILRA2More
Dasatinibhsa04390Hippo signaling pathway4.05E-067P35240, O95835, Q92796, P04628, Q9UJU2, O43623, Q13489NF2, LATS1, DLG3, WNT1, LEF1, SNAI2, BIRC3More
Dasatinibhsa04392Hippo signaling pathway - multiple species2.11E-053O95835, Q13153, Q6V0I7LATS1, PAK1, FAT4More
Dasatinibhsa04510Focal adhesion1.63E-035Q15942, P51636, P30281, P04049, P08069ZYX, CAV2, CCND3, RAF1, IGF1RMore
Dasatinibhsa04512ECM-receptor interaction2.77E-056P02452, P24821, P07359, P26012, P08514, P16070COL1A1, TNC, GP1BA, ITGB8, ITGA2B, CD44More
Dasatinibhsa04520Adherens junction1.81E-033Q13485, O43318, P08069SMAD4, MAP3K7, IGF1RMore
Dasatinibhsa04540Gap junction1.04E-059P17252, P22694, Q13509, P68371, P04049, Q9NRA1, Q9GZP0, P14416, Q14643PRKCA, PRKACB, TUBB3, TUBB2C, RAF1, PDGFC, PDGFD, DRD2, ITPR1More
Dasatinibhsa04550Signaling pathways regulating pluripotency of stem cells1.61E-035Q13873, P04049, Q02750, P08069, Q86SE9BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Dasatinibhsa04610Complement and coagulation cascades1.45E-084P09871, P0C0L4, P20023, P05107C1S, C4A, CR2, ITGB2More
Dasatinibhsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Dasatinibhsa04612Antigen processing and presentation1.47E-1112P13765, P48382, P01730, P26715, P26717, Q07444, Q13241, O43908, P01732, P30101, P11142, P01375HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, PDIA3, HSPA8, TNFMore
Dasatinibhsa04613Neutrophil extracellular trap formation3.49E-0929P19174, P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q99878, Q93077, P62807, Q16778, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539PLCG1, PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, H2AC14, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Dasatinibhsa04620Toll-like receptor signaling pathway2.48E-055Q13546, P01568, P01584, P31751, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, CCL4L2More
Dasatinibhsa04621NOD-like receptor signaling pathway2.66E-0517P01584, P07900, Q16539, Q14643, P23458, P45880, P10599, Q9H1Y0, P43490, O00463, P10415, P29728, Q05823, P01375, P09341, P49913, P12838IL1B, HSP90AA1, MAPK14, ITPR1, JAK1, VDAC2, TXN, ATG5, PBEF1, TRAF5, BCL2, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Dasatinibhsa04622RIG-I-like receptor signaling pathway1.29E-075P01568, Q9NQC7, Q13546, Q12933, P10145IFNA21, CYLD, RIPK1, TRAF2, IL8More
Dasatinibhsa04623Cytosolic DNA-sensing pathway1.82E-105P01584, P01568, Q13546, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, POLR3H, CCL4L2More
Dasatinibhsa04625C-type lectin receptor signaling pathway4.61E-0810Q9ULY5, P04049, Q13153, P01584, Q9NQC7, P20749, P01375, P31751, P0DP23, Q16539CLEC4E, RAF1, PAK1, IL1B, CYLD, BCL3, TNF, AKT2, CALM1, MAPK14More
Dasatinibhsa04630JAK-STAT signaling pathway1.01E-048P01106, P31751, P42224, P23458, P14784, P16871, Q13651, P04049MYC, AKT2, STAT1, JAK1, IL2RB, IL7R, IL10RA, RAF1More
Dasatinibhsa04640Hematopoietic cell lineage1.48E-1217P13612, P07359, P08514, P14778, P27930, P11215, P15144, P20023, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375ITGA4, GP1BA, ITGA2B, IL1R1, IL1R2, ITGAM, ANPEP, CR2, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNFMore
Dasatinibhsa04650Natural killer cell mediated cytotoxicity2.14E-2118P16298, P50591, P19174, P01375, P06239, O60880, P20963, P42338, Q02750, P04049, Q13153, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, PLCG1, TNF, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, PAK1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Dasatinibhsa04657IL-17 signaling pathway4.17E-0814P25963, P07900, P08238, O00463, Q12933, Q07955, Q16539, P49841, P09341, P14780, P04141, P80188, P01375, P06702NFKBIA, HSP90AA1, HSP90AB1, TRAF5, TRAF2, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, CSF2, LCN2, TNF, S100A9More
Dasatinibhsa04658Th1 and Th2 cell differentiation2.79E-3917P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, Q9UM47, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, RUNX3More
Dasatinibhsa04659Th17 cell differentiation2.32E-2920P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, Q13485, P07900, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD4, HSP90AA1, HSP90AB1, CD3E, CD3G, CD247More
Dasatinibhsa04660T cell receptor signaling pathway2.04E-2719P01375, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, Q13153, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, PAK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Dasatinibhsa04662B cell receptor signaling pathway3.23E-1513P31751, P42338, P20023, P60033, P13164, P16298, Q8WV28, P07948, P11912, P21854, Q8N149, Q02750, P04049AKT2, PIK3CB, CR2, CD81, IFITM1, PPP3CB, BLNK, LYN, CD79A, CD72, LILRA2, MAP2K1, RAF1More
Dasatinibhsa04664Fc epsilon RI signaling pathway1.57E-068P01375, P31751, Q16539, P42338, Q9UQC2, P07948, P04049, P09917TNF, AKT2, MAPK14, PIK3CB, GAB2, LYN, RAF1, ALOX5More
Dasatinibhsa04666Fc gamma R-mediated phagocytosis1.02E-037P08637, O75015, P42338, P04049, P23528, P06396, P14598FCGR3A, FCGR3B, PIK3CB, RAF1, CFL1, GSN, NCF1More
Dasatinibhsa04668TNF signaling pathway4.51E-0511P01375, Q12933, O00463, Q16539, Q99941, P18848, P01584, P20749, P14780, P20333, O95429TNF, TRAF2, TRAF5, MAPK14, CREBL1, ATF4, IL1B, BCL3, MMP9, TNFRSF1B, BAG4More
Dasatinibhsa04672Intestinal immune network for IgA production3.76E-033P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Dasatinibhsa04710Circadian rhythm1.65E-033O15516, Q16526, Q9Y478CLOCK, CRY1, PRKAB1More
Dasatinibhsa04713Circadian entrainment4.47E-0811P0DP23, P0DP24, Q13557, Q02153, P17252, P62873, P63218, P61952, Q14643, Q08828, P51828CALM1, CALM2, CAMK2D, GUCY1B3, PRKCA, GNB1, GNG5, GNG11, ITPR1, ADCY1, ADCY7More
Dasatinibhsa04714Thermogenesis4.42E-024Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Dasatinibhsa04720Long-term potentiation9.48E-1112P17252, Q13557, P16298, P0DP23, P0DP24, Q15418, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, CAMK2D, PPP3CB, CALM1, CALM2, RPS6KA1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Dasatinibhsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Dasatinibhsa04722Neurotrophin signaling pathway1.76E-0610Q05655, P31751, P04049, P49841, O43524, P48023, P52566, P51617, P10415, P0DP23PRKCD, AKT2, RAF1, GSK3B, FOXO3, FASLG, ARHGDIB, IRAK1, BCL2, CALM1More
Dasatinibhsa04723Retrograde endocannabinoid signaling1.69E-037Q14643, P17252, P62873, P61952, Q08828, O15239, Q16718ITPR1, PRKCA, GNB1, GNG11, ADCY1, NDUFA1, NDUFA5More
Dasatinibhsa04724Glutamatergic synapse2.84E-057O15399, Q08828, P62873, P63218, P50151, P61952, P15104GRIN2D, ADCY1, GNB1, GNG5, GNG10, GNG11, GLULMore
Dasatinibhsa04725Cholinergic synapse5.43E-0813Q08828, P51828, Q14643, P17252, P62873, P63218, P50151, P61952, P18848, Q13557, P42338, P31751, P10415ADCY1, ADCY7, ITPR1, PRKCA, GNB1, GNG5, GNG10, GNG11, ATF4, CAMK2D, PIK3CB, AKT2, BCL2More
Dasatinibhsa04726Serotonergic synapse1.33E-021P04049RAF1More
Dasatinibhsa04727GABAergic synapse2.26E-109Q08828, P51828, P62873, P63218, P50151, P61952, P15104, P46459, Q15111ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, NSF, PLCL1More
Dasatinibhsa04728Dopaminergic synapse1.01E-1019Q14643, P17252, P62873, P63218, P50151, P61952, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP23, P0DP24, O15516, P48058ITPR1, PRKCA, GNB1, GNG5, GNG10, GNG11, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM1, CALM2, CLOCK, GRIA4More
Dasatinibhsa04730Long-term depression3.10E-034Q14344, P08069, P04049, P07948GNA13, IGF1R, RAF1, LYNMore
Dasatinibhsa04740Olfactory transduction1.31E-064P62873, Q13557, P0DP23, P0DP24GNB1, CAMK2D, CALM1, CALM2More
Dasatinibhsa04742Taste transduction1.18E-032P30939, P17612HTR1F, PRKACAMore
Dasatinibhsa04744Phototransduction4.62E-123P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Dasatinibhsa04750Inflammatory mediator regulation of TRP channels3.20E-1112P14778, P01584, Q08828, P51828, Q13557, P19174, P42338, P24723, Q04759, P0DP23, P0DP24, P01042IL1R1, IL1B, ADCY1, ADCY7, CAMK2D, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1, CALM2, KNG1More
Dasatinibhsa04810Regulation of actin cytoskeleton1.78E-026Q13009, P04049, P11215, P16144, P60709, P01042TIAM1, RAF1, ITGAM, ITGB4, ACTB, KNG1More
Dasatinibhsa04910Insulin signaling pathway2.40E-053P0DP23, P04049, P31751CALM1, RAF1, AKT2More
Dasatinibhsa04911Insulin secretion1.04E-065Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Dasatinibhsa04912GnRH signaling pathway1.15E-069P17252, Q08828, P51828, P18848, Q9Y6R4, Q14643, P0DP23, P04049, P45985PRKCA, ADCY1, ADCY7, ATF4, MAP3K4, ITPR1, CALM1, RAF1, MAP2K4More
Dasatinibhsa04913Ovarian steroidogenesis8.40E-042P06213, P08069INSR, IGF1RMore
Dasatinibhsa04914Progesterone-mediated oocyte maturation2.17E-099P08069, Q17RY0, P42338, Q13370, Q9Y6D9, P08238, P51812, Q02750, P04049IGF1R, CPEB4, PIK3CB, PDE3B, MAD1L1, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Dasatinibhsa04915Estrogen signaling pathway1.19E-1213P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P08238, P0DMV8, P11142, P0DP23, P0DP24, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSP90AB1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Dasatinibhsa04916Melanogenesis7.31E-044P0DP23, Q08828, P51828, P04049CALM1, ADCY1, ADCY7, RAF1More
Dasatinibhsa04917Prolactin signaling pathway3.49E-042P31751, P04049AKT2, RAF1More
Dasatinibhsa04918Thyroid hormone synthesis2.47E-045Q08828, Q99941, P18848, P02768, P05543ADCY1, CREBL1, ATF4, ALB, SERPINA7More
Dasatinibhsa04919Thyroid hormone signaling pathway1.21E-047P19174, P04049, P42224, P60709, Q13547, Q9UM47, P01106PLCG1, RAF1, STAT1, ACTB, HDAC1, NOTCH3, MYCMore
Dasatinibhsa04920Adipocytokine signaling pathway6.38E-045Q9Y478, Q96RR4, Q15831, P20333, P31751PRKAB1, CAMKK2, STK11, TNFRSF1B, AKT2More
Dasatinibhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Dasatinibhsa04922Glucagon signaling pathway3.10E-047P14618, P06737, Q12778, P31751, Q13370, P0DP23, Q14643PKM2, PYGL, FOXO1, AKT2, PDE3B, CALM1, ITPR1More
Dasatinibhsa04923Regulation of lipolysis in adipocytes5.39E-064Q08828, P51828, P06213, P31751ADCY1, ADCY7, INSR, AKT2More
Dasatinibhsa04924Renin secretion4.28E-095P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Dasatinibhsa04925Aldosterone synthesis and secretion1.86E-098Q99941, P18848, Q08828, P51828, P0DP23, P0DP24, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM1, CALM2, CAMK2D, ATP2B4More
Dasatinibhsa04926Relaxin signaling pathway1.62E-0714P31751, P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P49767, Q08828, P51828, P04049, P30679, P49407AKT2, PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, VEGFC, ADCY1, ADCY7, RAF1, GNA15, ARRB1More
Dasatinibhsa04927Cortisol synthesis and secretion2.32E-054Q99941, P18848, Q08828, P51828CREBL1, ATF4, ADCY1, ADCY7More
Dasatinibhsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Dasatinibhsa04929GnRH secretion6.93E-064P42338, P31751, P49407, P04049PIK3CB, AKT2, ARRB1, RAF1More
Dasatinibhsa04930Type II diabetes mellitus6.29E-053P06213, Q05655, Q02156INSR, PRKCD, PRKCEMore
Dasatinibhsa04932Non-alcoholic fatty liver disease2.08E-1214P31751, P01375, P49841, Q14790, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, O95298, P19404AKT2, TNF, GSK3B, CASP8, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2, NDUFV2More
Dasatinibhsa04933AGE-RAGE signaling pathway in diabetic complications1.27E-025P42224, P10415, Q12778, P49767, P17252STAT1, BCL2, FOXO1, VEGFC, PRKCAMore
Dasatinibhsa04934Cushing syndrome5.10E-076Q99941, P18848, Q08828, P51828, O15169, Q13557CREBL1, ATF4, ADCY1, ADCY7, AXIN1, CAMK2DMore
Dasatinibhsa04935Growth hormone synthesis, secretion and action5.87E-046Q08828, P51828, P04049, P18848, P31751, P45985ADCY1, ADCY7, RAF1, ATF4, AKT2, MAP2K4More
Dasatinibhsa04940Type I diabetes mellitus7.38E-044P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Dasatinibhsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Dasatinibhsa04964Proximal tubule bicarbonate reclamation4.48E-021P00918CA2More
Dasatinibhsa04966Collecting duct acid secretion1.95E-033Q13488, P00918, Q9Y666TCIRG1, CA2, SLC12A7More
Dasatinibhsa04970Salivary secretion1.44E-1010P07550, Q08828, P51828, P22694, Q14643, P23634, P0DP24, P0DP23, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B4, CALM2, CALM1, GUCY1B3, CAMPMore
Dasatinibhsa04971Gastric acid secretion3.36E-076Q08828, P51828, P15311, P0DP24, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM2, CALM1, CAMK2DMore
Dasatinibhsa04973Carbohydrate digestion and absorption2.41E-021P31751AKT2More
Dasatinibhsa04974Protein digestion and absorption1.22E-032Q7Z2H8, P02452SLC36A1, COL1A1More
Dasatinibhsa04975Fat digestion and absorption4.83E-021O14494PLPP1More
Dasatinibhsa04976Bile secretion1.97E-043Q08828, P51828, Q14032ADCY1, ADCY7, BAATMore
Dasatinibhsa04979Cholesterol metabolism1.37E-023P38571, P61916, P45880LIPA, NPC2, VDAC2More
Dasatinibhsa05010Alzheimer disease4.59E-1029P49768, Q92542, O15239, Q16718, O95298, P19404, O14521, P05496, P13073, P12074, Q14643, Q00535, O75460, P0DP23, P01584, Q12933, P18848, Q71U36, Q13509, P68371, O15169, P67870, P31751, P05141, P21796, P45880, Q08752, P28070, P43686PSEN1, NCSTN, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, CDK5, ERN1, CALM1, IL1B, TRAF2, ATF4, TUBA1A, TUBB3, TUBB2C, AXIN1, CSNK2B, AKT2, SLC25A5, VDAC1, VDAC2, PPID, PSMB4, PSMC4More
Dasatinibhsa05012Parkinson disease1.62E-0724O15239, Q16718, O95298, P19404, O14521, P13073, P12074, P05496, P05141, P12236, P21796, P45880, O75460, P18848, P28070, P43686, Q14643, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509, P68371NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, COX4I1, COX6A1, ATP5G1, SLC25A5, SLC25A6, VDAC1, VDAC2, ERN1, ATF4, PSMB4, PSMC4, ITPR1, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3, TUBB2CMore
Dasatinibhsa05014Amyotrophic lateral sclerosis4.18E-025P19404, P12074, O75460, P28070, Q8TEV9NDUFV2, COX6A1, ERN1, PSMB4, SMCR8More
Dasatinibhsa05016Huntington disease4.61E-0816O95298, P19404, P13073, P12074, Q13547, P24928, P30876, P62487, P05141, P21796, P45880, O75460, Q71U36, Q13509, P28070, O00232NDUFC2, NDUFV2, COX4I1, COX6A1, HDAC1, POLR2A, POLR2B, POLR2G, SLC25A5, VDAC1, VDAC2, ERN1, TUBA1A, TUBB3, PSMB4, PSMD12More
Dasatinibhsa05017Spinocerebellar ataxia1.88E-049Q92915, O75460, Q8TB72, O15399, P42338, P31751, P28070, P05141, P21796FGF14, ERN1, PUM2, GRIN2D, PIK3CB, AKT2, PSMB4, SLC25A5, VDAC1More
Dasatinibhsa05020Prion disease3.30E-0827P01584, P46531, P0DMV8, P11142, O15239, Q16718, O95298, P19404, O14521, P05496, P13073, P12074, Q14643, P18848, P05141, P12236, P21796, P45880, P28070, P43686, Q71U36, Q13509, P68371, P67870, Q99941, P14598, Q15080IL1B, NOTCH1, HSPA1A, HSPA8, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, ATF4, SLC25A5, SLC25A6, VDAC1, VDAC2, PSMB4, PSMC4, TUBA1A, TUBB3, TUBB2C, CSNK2B, CREBL1, NCF1, NCF4More
Dasatinibhsa05022Pathways of neurodegeneration - multiple diseases4.70E-1139Q14643, Q71U36, Q13509, P68371, P67870, P10415, O15239, Q16718, O95298, P19404, O14521, P13073, P12074, P05496, Q06055, Q8TEV9, P21796, O75460, P18848, Q12933, Q13561, P19174, P05141, P45880, P17252, P20333, Q15078, Q00535, O15169, P01584, P49768, Q08752, O15020, P0DP23, P0DP24, Q13557, P62987, P28070, P43686ITPR1, TUBA1A, TUBB3, TUBB2C, CSNK2B, BCL2, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, COX4I1, COX6A1, ATP5G1, ATP5G2, SMCR8, VDAC1, ERN1, ATF4, TRAF2, DCTN2, PLCG1, SLC25A5, VDAC2, PRKCA, TNFRSF1B, CDK5R1, CDK5, AXIN1, IL1B, PSEN1, PPID, SPTBN2, CALM1, CALM2, CAMK2D, UBA52, PSMB4, PSMC4More
Dasatinibhsa05030Cocaine addiction5.99E-033Q00535, Q99941, P18848CDK5, CREBL1, ATF4More
Dasatinibhsa05031Amphetamine addiction1.12E-066P0DP23, P0DP24, Q13557, Q99941, P18848, Q13547CALM1, CALM2, CAMK2D, CREBL1, ATF4, HDAC1More
Dasatinibhsa05032Morphine addiction5.68E-032P78334, P32298GABRE, GRK4More
Dasatinibhsa05033Nicotine addiction4.01E-021P78334GABREMore
Dasatinibhsa05034Alcoholism2.24E-0614Q99941, P18848, Q13547, P0DP23, P0DP24, P62873, P63218, P61952, P04049, P0C0S5, Q93077, P62807, Q16778, O60814CREBL1, ATF4, HDAC1, CALM1, CALM2, GNB1, GNG5, GNG11, RAF1, H2AFZ, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12More
Dasatinibhsa05100Bacterial invasion of epithelial cells3.14E-033Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Dasatinibhsa05110Vibrio cholerae infection1.74E-045Q13488, Q99437, P17252, P19174, P17612TCIRG1, ATP6V0B, PRKCA, PLCG1, PRKACAMore
Dasatinibhsa05120Epithelial cell signaling in Helicobacter pylori infection4.31E-1111Q16539, Q99437, Q13153, P09341, P19875, P10145, P19174, P25024, P25025, P41240, P07948MAPK14, ATP6V0B, PAK1, CXCL1, CXCL2, IL8, PLCG1, CXCR1, CXCR2, CSK, LYNMore
Dasatinibhsa05130Pathogenic Escherichia coli infection2.77E-039P16333, Q13509, P60709, P25963, P04406, P29350, Q15438, P35579, P55061NCK1, TUBB3, ACTB, NFKBIA, GAPDH, PTPN6, PSCD1, MYH9, TEGTMore
Dasatinibhsa05131Shigellosis3.55E-0618Q12933, Q13546, P68431, Q05655, Q02156, Q9UDY8, Q9NQL2, P0CG47, Q14141, Q14247, Q96JJ3, Q05397, Q14643, Q12778, Q13315, P10415, Q08752, P07737TRAF2, RIPK1, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCD, PRKCE, MALT1, RRAGD, UBB, SEPT6, CTTN, ELMO2, PTK2, ITPR1, FOXO1, ATM, BCL2, PPID, PFN1More
Dasatinibhsa05132Salmonella infection1.26E-0920P51617, P25963, P08238, P04049, Q9UJU2, P01106, P84095, P60709, Q13546, Q13489, P10415, P04406, O75369, P07737, O60603, Q9BQS8, Q13561, Q13509, P68371, P49754IRAK1, NFKBIA, HSP90AB1, RAF1, LEF1, MYC, RHOG, ACTB, RIPK1, BIRC3, BCL2, GAPDH, FLNB, PFN1, TLR2, FYCO1, DCTN2, TUBB3, TUBB2C, VPS41More
Dasatinibhsa05133Pertussis1.43E-053P05107, P10145, P0C0L4ITGB2, IL8, C4AMore
Dasatinibhsa05134Legionellosis5.15E-109P01584, P25963, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Dasatinibhsa05135Yersinia infection1.86E-048Q05397, P51812, P06239, P19174, Q02750, P42338, Q96JJ3, P01732PTK2, RPS6KA3, LCK, PLCG1, MAP2K1, PIK3CB, ELMO2, CD8AMore
Dasatinibhsa05140Leishmaniasis5.27E-1113P13612, O75015, P14598, P11215, P42224, P13765, O60603, P25963, P01375, P29350, P49006, Q16539, Q15080ITGA4, FCGR3B, NCF1, ITGAM, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, PTPN6, MARCKSL1, MAPK14, NCF4More
Dasatinibhsa05142Chagas disease2.70E-022P48023, Q14790FASLG, CASP8More
Dasatinibhsa05143African trypanosomiasis1.54E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Dasatinibhsa05144Malaria4.06E-069P60033, P69905, P68871, O60603, P01375, P05107, P35443, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, ITGB2, THBS4, IL8, KLRK1More
Dasatinibhsa05145Toxoplasmosis5.18E-048P10415, Q13489, P23458, P42224, P13765, P0DMV8, O60603, P29965BCL2, BIRC3, JAK1, STAT1, HLA-DOB, HSPA1A, TLR2, CD40LGMore
Dasatinibhsa05146Amoebiasis4.70E-1912P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Dasatinibhsa05150Staphylococcus aureus infection5.80E-0915P09871, P0C0L4, P21730, P21462, O75015, P31995, P13765, P13646, Q14532, P05107, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, FCGR2C, HLA-DOB, KRT13, KRT32, ITGB2, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Dasatinibhsa05152Tuberculosis2.08E-0612P04049, Q13488, P0DP23, P42224, P48382, O60603, P31751, P10415, P13765, P01568, Q9UDY8, P51617RAF1, TCIRG1, CALM1, STAT1, RFX5, TLR2, AKT2, BCL2, HLA-DOB, IFNA21, MALT1, IRAK1More
Dasatinibhsa05160Hepatitis C1.84E-059Q13546, P01568, P52630, P60033, Q9NZJ5, P04049, P49841, P01375, P48023RIPK1, IFNA21, STAT2, CD81, EIF2AK3, RAF1, GSK3B, TNF, FASLGMore
Dasatinibhsa05161Hepatitis B4.32E-034P04049, Q99941, P18848, P27348RAF1, CREBL1, ATF4, YWHAQMore
Dasatinibhsa05162Measles2.05E-056P23458, P31751, P0DMV8, P01584, P67870, Q9NP90JAK1, AKT2, HSPA1A, IL1B, CSNK2B, RAB9BMore
Dasatinibhsa05163Human cytomegalovirus infection1.17E-1127P31751, P04049, P01375, P62873, P63218, P50151, P61952, Q14643, P0DP23, P0DP24, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P30101, P61769AKT2, RAF1, TNF, GNB1, GNG5, GNG10, GNG11, ITPR1, CALM1, CALM2, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, PDIA3, B2MMore
Dasatinibhsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Dasatinibhsa05165Human papillomavirus infection7.06E-0517P16144, P02452, P24821, Q16363, Q05086, P30281, Q9UM47, P01568, P42224, P01889, P10321, Q13488, Q99437, Q13362, Q12778, P04628, Q13315ITGB4, COL1A1, TNC, LAMA4, UBE3A, CCND3, NOTCH3, IFNA21, STAT1, HLA-B, HLA-C, TCIRG1, ATP6V0B, PPP2R5C, FOXO1, WNT1, ATMMore
Dasatinibhsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Dasatinibhsa05167Kaposi sarcoma-associated herpesvirus infection1.88E-0615P01568, P31751, P42224, P25963, P62873, P63218, P19875, P19174, Q14643, P04049, P07948, P01106, P04141, P0DP23, Q9UJU2IFNA21, AKT2, STAT1, NFKBIA, GNB1, GNG5, CXCL2, PLCG1, ITPR1, RAF1, LYN, MYC, CSF2, CALM1, LEF1More
Dasatinibhsa05168Herpes simplex virus 1 infection3.68E-0521O00463, O60603, P25963, Q05823, P42224, Q07955, Q01130, Q13243, Q16629, P42338, Q9Y2A4, Q13398, P51522, Q9NR11, P17097, P17038, Q03923, P52738, O75820, Q9UDV6, P10415TRAF5, TLR2, NFKBIA, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, SFRS7, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF302, ZNF7, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212, BCL2More
Dasatinibhsa05169Epstein-Barr virus infection9.91E-0919P13765, P01106, Q13547, O00463, P10415, P42338, P07948, P30101, Q13761, P24522, O75293, P30279, P42224, P01375, O60603, P29728, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, BCL2, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, CCND2, STAT1, TNF, TLR2, OAS2, CD3E, CD3G, CD247More
Dasatinibhsa05170Human immunodeficiency virus 1 infection4.56E-0816P31751, P04049, Q02750, P62873, P62879, P16298, P0DP23, Q05397, P17252, Q14643, P01568, P51617, O60603, Q13315, P10415, Q9Y6Q5AKT2, RAF1, MAP2K1, GNB1, GNB2, PPP3CB, CALM1, PTK2, PRKCA, ITPR1, IFNA21, IRAK1, TLR2, ATM, BCL2, AP1M2More
Dasatinibhsa05171Coronavirus disease - COVID-191.50E-1622P23396, P62753, P25398, P62249, P42677, P40429, P36578, Q02878, P62917, P32969, P27635, P26373, Q07020, P46778, P46776, P62899, P62910, P18077, P61927, P61513, P62945, P05386RPS3, RPS6, RPS12, RPS16, RPS27, RPL13A, RPL4, RPL6, RPL8, RPL9, RPL10, RPL13, RPL18, RPL21, RPL27A, RPL31, RPL32, RPL35A, RPL37, RPL37A, RPL41, RPLP1More
Dasatinibhsa05200Pathways in cancer3.17E-1036Q16363, P42338, P07900, P08238, P42224, P25963, P19174, P01106, Q9UJU2, P17252, P43246, Q13485, P20585, P52701, Q13547, P14923, P30279, P10415, Q13489, Q13077, P49767, P14921, Q12778, P31751, P25116, P62873, P63218, Q9UM47, P78417, O75293, P0DP23, Q13557, P01568, P14784, P40189, P01042LAMA4, PIK3CB, HSP90AA1, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, LEF1, PRKCA, MSH2, SMAD4, MSH3, MSH6, HDAC1, JUP, CCND2, BCL2, BIRC3, TRAF1, VEGFC, ETS1, FOXO1, AKT2, F2R, GNB1, GNG5, NOTCH3, GSTO1, GADD45B, CALM1, CAMK2D, IFNA21, IL2RB, IL6ST, KNG1More
Dasatinibhsa05202Transcriptional misregulation in cancer1.73E-1019Q12778, Q13315, P41732, P14780, P27930, Q15744, Q16548, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522FOXO1, ATM, TSPAN7, MMP9, IL1R2, CEBPE, BCL2A1, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45AMore
Dasatinibhsa05203Viral carcinogenesis3.85E-0719Q12933, Q99941, P18848, P06746, P07948, P30279, P30281, P27348, P29083, Q7KZF4, Q13547, P06396, P12814, P01889, P10321, P06493, P62807, Q16778, O60814TRAF2, CREBL1, ATF4, POLB, LYN, CCND2, CCND3, YWHAQ, GTF2E1, SND1, HDAC1, GSN, ACTN1, HLA-B, HLA-C, CDK1, HIST1H2BC, HIST2H2BE, H2BC12More
Dasatinibhsa05205Proteoglycans in cancer6.79E-0510Q13009, Q12955, O75369, P60709, P04049, P01106, P08069, P19174, P29350, P08962TIAM1, ANK3, FLNB, ACTB, RAF1, MYC, IGF1R, PLCG1, PTPN6, CD63More
Dasatinibhsa05206MicroRNAs in cancer1.30E-027P30304, P09493, Q9UM47, P20827, P17252, P19174, P04049CDC25A, TPM1, NOTCH3, EFNA1, PRKCA, PLCG1, RAF1More
Dasatinibhsa05210Colorectal cancer1.47E-049Q9UKG1, Q13485, P43246, P04049, P01106, P52701, P20585, P37173, O75293APPL1, SMAD4, MSH2, RAF1, MYC, MSH6, MSH3, TGFBR2, GADD45BMore
Dasatinibhsa05211Renal cell carcinoma5.09E-053Q13153, P31751, P04049PAK1, AKT2, RAF1More
Dasatinibhsa05212Pancreatic cancer3.26E-057P42338, P31751, P04049, Q15311, P23458, P42224, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, GADD45BMore
Dasatinibhsa05213Endometrial cancer8.16E-042P31751, P04049AKT2, RAF1More
Dasatinibhsa05214Glioma1.28E-099P08069, P0DP23, Q13557, P17252, P04049, P42338, P31751, P19174, O75293IGF1R, CALM1, CAMK2D, PRKCA, RAF1, PIK3CB, AKT2, PLCG1, GADD45BMore
Dasatinibhsa05215Prostate cancer2.34E-045P10415, Q12778, P08069, Q9NRA1, P04049BCL2, FOXO1, IGF1R, PDGFC, RAF1More
Dasatinibhsa05217Basal cell carcinoma4.31E-022P04628, Q9UJU2WNT1, LEF1More
Dasatinibhsa05218Melanoma5.24E-063P08069, P31751, P04049IGF1R, AKT2, RAF1More
Dasatinibhsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Dasatinibhsa05220Chronic myeloid leukemia9.63E-042P31751, P04049AKT2, RAF1More
Dasatinibhsa05221Acute myeloid leukemia8.73E-045P31751, P42338, P04049, Q15744, P11215AKT2, PIK3CB, RAF1, CEBPE, ITGAMMore
Dasatinibhsa05222Small cell lung cancer4.78E-021P31751AKT2More
Dasatinibhsa05223Non-small cell lung cancer3.49E-042P31751, P04049AKT2, RAF1More
Dasatinibhsa05224Breast cancer2.75E-036P04049, P08069, P49841, Q92837, P04637, P24522RAF1, IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Dasatinibhsa05225Hepatocellular carcinoma1.65E-042P04049, P08069RAF1, IGF1RMore
Dasatinibhsa05226Gastric cancer6.81E-042P04049, P31751RAF1, AKT2More
Dasatinibhsa05230Central carbon metabolism in cancer1.12E-032P04049, P31751RAF1, AKT2More
Dasatinibhsa05231Choline metabolism in cancer1.52E-0810P04049, P31751, Q9Y259, P19174, P23743, P49619, Q16760, O14986, O14494, P17252RAF1, AKT2, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PLPP1, PRKCAMore
Dasatinibhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.13E-1617P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P04049, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, RAF1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Dasatinibhsa05310Asthma8.31E-113P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Dasatinibhsa05320Autoimmune thyroid disease1.27E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Dasatinibhsa05321Inflammatory bowel disease6.86E-187O60603, P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Dasatinibhsa05322Systemic lupus erythematosus6.78E-0715P08637, O75015, P08246, P08311, P09871, P01375, P10747, P13765, P29965, Q6FI13, P62807, Q16778, P68431, P14678, P12814FCGR3A, FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2BC, HIST2H2BE, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SNRPB, ACTN1More
Dasatinibhsa05323Rheumatoid arthritis7.52E-068P01375, Q06643, P13765, Q13488, P10747, P09341, P19875, O60603TNF, LTB, HLA-DOB, TCIRG1, CD28, CXCL1, CXCL2, TLR2More
Dasatinibhsa05330Allograft rejection7.88E-055P13765, P29965, P48023, P10747, P01375HLA-DOB, CD40LG, FASLG, CD28, TNFMore
Dasatinibhsa05332Graft-versus-host disease3.07E-166P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Dasatinibhsa05340Primary immunodeficiency4.07E-056P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Dasatinibhsa05410Hypertrophic cardiomyopathy3.63E-022P26012, P09493ITGB8, TPM1More
Dasatinibhsa05412Arrhythmogenic right ventricular cardiomyopathy4.48E-021P54284CACNB3More
Dasatinibhsa05414Dilated cardiomyopathy3.78E-034P54284, P26012, P09493, P26678CACNB3, ITGB8, TPM1, PLNMore
Dasatinibhsa05415Diabetic cardiomyopathy4.77E-049P17252, P30405, P14598, Q15080, Q16718, O14521, Q16539, P14780, P37173PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, MAPK14, MMP9, TGFBR2More
Dasatinibhsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Dasatinibhsa05418Fluid shear stress and atherosclerosis1.58E-0613Q16539, P31751, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, AKT2, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Dasatinib (SDC: 11.14)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P06239LCKTyrosineNoneprotein kinase LckReported00.057610.72872.7575
P07947YES1TyrosineNoneprotein kinase YesReported00.12120.43450.1651.0947
P09619PDGFRBPlateletNonederived growth factor receptor betaReported00.04960.94440.74082.6543
Q92570NR4A3Nuclear receptor subfamily 4 group A member 3Reported00.33030.00670.3450.5235
P41240CSKTyrosineNoneprotein kinase CSKReported00.69860.36260.10231.1768
P09769FGRTyrosineNoneprotein kinase FgrReported00.06220.32440.2250.9049
P11142HSPA8Heat shock cognate 71 kDa proteinReported00.96820.07730.67291.3115
P07948LYNTyrosineNoneprotein kinase LynReported00.0910.53190.6061.7154
Q16539MAPK14MitogenNoneactivated protein kinase 14Reported10.0149113.0075
Q8IVH8MAP4K3MitogenNoneactivated protein kinase kinase kinase kinase 3Predicted00.38330.26730.14870.875
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
O14976GAKCyclinNoneGNoneassociated kinasePredicted10.57280.256200.7989
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
Q9Y6R4MAP3K4MitogenNoneactivated protein kinase kinase kinase 4Predicted00.35280.24520.1730.8399
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
Q9P289STK26Serine/threonineNoneprotein kinase 26Predicted10.02850.262800.5399
Q8NI60CABC1Atypical kinase COQ8A, mitochondrialPredicted00.62760.245200.8043
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
P24723PRKCHProtein kinase C eta typePredicted00.19550.32940.20480.9614
Q15418RPS6KA1Ribosomal protein S6 kinase alphaNone1Predicted10.8320.32450.41461.4796
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
Q9UEE5STK17ASerine/threonineNoneprotein kinase 17APredicted00.35040.337600.8504
Q2M2I8AAK1AP2Noneassociated protein kinase 1Predicted10.37690.328800.846
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
Q07912TNK2Activated CDC42 kinase 1Predicted00.0090.347200.6988
Q99759MAP3K3MitogenNoneactivated protein kinase kinase kinase 3Predicted00.35450.24520.43781.1055
P51955NEK2Serine/threonineNoneprotein kinase Nek2Predicted00.65990.369201.0684
Q13153PAK1Serine/threonineNoneprotein kinase PAK 1Predicted10.46470.34710.78191.7084
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
P22694PRKACBcAMPNonedependent protein kinase catalytic subunit betaPredicted00.37370.298411.7836
Q9Y6E0STK24Serine/threonineNoneprotein kinase 24Predicted00.54580.245200.7634
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
Q13523PRPF4BSerine/threonineNoneprotein kinase PRP4 homologPredicted00.13760.245200.5593
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
O95835LATS1Serine/threonineNoneprotein kinase LATS1Predicted00.43320.24520.02170.7288
O43283MAP3K13MitogenNoneactivated protein kinase kinase kinase 13Predicted00.45650.24520.14870.8674
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P51817PRKXcAMPNonedependent protein kinase catalytic subunit PRKXPredicted00.40630.276500.7562
O95747OXSR1Serine/threonineNoneprotein kinase OSR1Predicted00.18390.245200.5825
Q00536PCTK1CyclinNonedependent kinase 16Predicted00.27140.25600.6478
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
Q16513PKN2Serine/threonineNoneprotein kinase N2Predicted00.04210.27780.33910.9157
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
Q9UEW8STK39STE20/SPS1Nonerelated prolineNonealanineNonerich protein kinasePredicted00.25730.245200.6191
Q96BR1SGK3Serine/threonineNoneprotein kinase Sgk3Predicted00.0260.26840.31140.8612
Q02156PRKCEProtein kinase C epsilon typePredicted00.11750.52870.53771.6539
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q9H422HIPK3HomeodomainNoneinteracting protein kinase 3Predicted00.3650.25080.2180.902
O94806PRKD3Serine/threonineNoneprotein kinase D3Predicted00.23120.24340.16920.7715
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
Q15831STK11Serine/threonineNoneprotein kinase STK11Predicted00.15110.24410.45491.0186
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
Q8IVW4CDKL3CyclinNonedependent kinaseNonelike 3Predicted00.41490.241600.6906
Q13873BMPR2Bone morphogenetic protein receptor typeNone2Predicted10.34760.24520.35481.019
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
O75460ERN1Serine/threonineNoneprotein kinase/endoribonuclease IRE1Predicted10.68060.29440.5571.4862
P51617IRAK1InterleukinNone1 receptorNoneassociated kinase 1Predicted00.02380.30.94441.5563
P31751AKT2RACNonebeta serine/threonineNoneprotein kinasePredicted00.46620.485612.2044
P30530AXLTyrosineNoneprotein kinase receptor UFOPredicted10.37970.53650.16371.4264
Q16566CAMK4Calcium/calmodulinNonedependent protein kinase type IVPredicted00.07180.24410.61761.1417
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
P21860ERBB3Receptor tyrosineNoneprotein kinase erbBNone3Predicted00.1260.27290.47881.0876
P07332FESTyrosineNoneprotein kinase Fes/FpsPredicted00.27220.26280.15130.8131
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
Q9H2K8TAOK3Serine/threonineNoneprotein kinase TAO3Predicted00.06460.24520.14870.6715
Q9NQU5PAK6Serine/threonineNoneprotein kinase PAK 6Predicted00.4090.26690.50031.2386
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
O43318MAP3K7MitogenNoneactivated protein kinase kinase kinase 7Predicted00.00590.364911.7327
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
P32298GRK4G proteinNonecoupled receptor kinase 4Predicted00.03520.23860.29480.7896
P45985MAP2K4Dual specificity mitogenNoneactivated protein kinase kinase 4Predicted00.42480.24730.74031.4474
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
Q9UBU7DBF4Protein DBF4 homolog APredicted00.00750.19610.2590.655
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
Q9NZJ5EIF2AK3Eukaryotic translation initiation factor 2Nonealpha kinase 3Predicted10.09390.15740.63981.0015
Q15046KARSLysineNoneNonetRNA ligasePredicted00.10330.0580.00270.1702
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P42677RPS2740S ribosomal protein S27Predicted00.37810.02160.4320.6644
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P42229STAT5ASignal transducer and activator of transcription 5APredicted10.21190.01190.78460.9144
P0DMV8HSPA1AHeat shock 70 kDa protein 1APredicted00.72860.01010.67291.0573
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
P42226STAT6Signal transducer and activator of transcription 6Predicted00.31610.03530.5090.7378
Q14765STAT4Signal transducer and activator of transcription 4Predicted00.16770.00210.44960.5377
P42224STAT1Signal transducer and activator of transcription 1Nonealpha/betaPredicted10.22450.042511.1973
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P10826RARBRetinoic acid receptor betaPredicted00.00940.34660.30050.9983
Q15131CDK10CyclinNonedependent kinase 10Predicted00.36120.032300.2453
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
Q13239SLASrcNonelikeNoneadapterPredicted10.16050.009800.0999
O60880SH2D1ASH2 domainNonecontaining protein 1APredicted00.03520.01650.18070.2313
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
LCKP06239IC500.4
LCKP06239IC500.4
LCKP06239IC503
LCKP06239Kd0.2
LCKP06239Kd0.2
LCKP06239Kd0.2
YES1P07947IC500.5
YES1P07947IC50<0.500000
YES1P07947IC50<1.000000
YES1P07947Kd0.3
YES1P07947Kd0.3
YES1P07947Kd0.3
PDGFRBP09619IC5028
PDGFRBP09619Kd0.63
PDGFRBP09619Kd0.63
CSKP41240Kd1
CSKP41240Kd1
FGRP09769IC50<10.00
FGRP09769Kd0.5
FGRP09769Kd0.5
FGRP09769Kd0.5
LYNP07948IC50<10.00
LYNP07948Kd0.57
LYNP07948Kd0.57
MAPK14Q16539IC50100
MAPK14Q16539Kd27
MAPK14Q16539Kd230
MAPK14Q16539Kd495