PharmaCoNets of Dapiprazole (SPCN: 244.07 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Dapiprazolehsa00030Pentose phosphate pathway1.62E-064P60891, P51854, P11413, P37837PRPS1, TKTL1, G6PD, TALDO1More
Dapiprazolehsa00040Pentose and glucuronate interconversions4.00E-021P15121AKR1B1More
Dapiprazolehsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Dapiprazolehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Dapiprazolehsa00190Oxidative phosphorylation1.10E-033Q16718, P36542, O14521NDUFA5, ATP5C1, SDHDMore
Dapiprazolehsa00220Arginine biosynthesis1.26E-033P15104, P05089, P49448GLUL, ARG1, GLUD2More
Dapiprazolehsa00250Alanine, aspartate and glutamate metabolism2.42E-021P15104GLULMore
Dapiprazolehsa00310Lysine degradation1.11E-043Q96KQ7, Q02809, P51648EHMT2, PLOD1, ALDH3A2More
Dapiprazolehsa00350Tyrosine metabolism3.40E-021P28332ADH6More
Dapiprazolehsa00480Glutathione metabolism1.35E-021P11413G6PDMore
Dapiprazolehsa00500Starch and sucrose metabolism3.06E-054O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Dapiprazolehsa00512Mucin type O-glycan biosynthesis4.86E-022O95395, Q9NY28GCNT3, GALNT8More
Dapiprazolehsa00520Amino sugar and nucleotide sugar metabolism1.59E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Dapiprazolehsa00562Inositol phosphate metabolism1.78E-034P27987, P19174, P42338, Q02252ITPKB, PLCG1, PIK3CB, ALDH6A1More
Dapiprazolehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Dapiprazolehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Dapiprazolehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Dapiprazolehsa00600Sphingolipid metabolism4.77E-023Q9BX95, O14494, P06280SGPP1, PLPP1, GLAMore
Dapiprazolehsa00603Glycosphingolipid biosynthesis - globo and isoglobo series7.10E-032P06865, O75752HEXA, B3GALNT1More
Dapiprazolehsa00620Pyruvate metabolism3.90E-022P07195, P11766LDHB, ADH5More
Dapiprazolehsa00630Glyoxylate and dicarboxylate metabolism9.04E-092P40925, P15104MDH1, GLULMore
Dapiprazolehsa00730Thiamine metabolism1.55E-032P05186, P24666ALPL, ACP1More
Dapiprazolehsa00760Nicotinate and nicotinamide metabolism3.52E-021P21589NT5EMore
Dapiprazolehsa00770Pantothenate and CoA biosynthesis4.29E-042O95498, Q9NRN7VNN2, AASDHPPTMore
Dapiprazolehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Dapiprazolehsa00830Retinol metabolism3.93E-023P00352, Q9BPW9, O75911ALDH1A1, DHRS9, DHRS3More
Dapiprazolehsa00910Nitrogen metabolism2.42E-021P15104GLULMore
Dapiprazolehsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Dapiprazolehsa00980Metabolism of xenobiotics by cytochrome P4506.26E-054P78417, P28332, P09211, P11712GSTO1, ADH6, GSTP1, CYP2C9More
Dapiprazolehsa00982Drug metabolism - cytochrome P4508.40E-043P11712, P78417, P28332CYP2C9, GSTO1, ADH6More
Dapiprazolehsa00983Drug metabolism - other enzymes1.61E-053P04183, P32320, P05164TK1, CDA, MPOMore
Dapiprazolehsa01100Metabolic pathways1.17E-0230Q9NR34, P05089, P30041, P32320, P20839, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, P08237, Q86XP1, Q9HCC0, P33121, Q9UHK6, Q86VZ5, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q9NVH6MAN1C1, ARG1, PRDX6, CDA, IMPDH1, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, PFKM, DGKH, MCCC2, ACSL1, AMACR, SGMS1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, TMLHEMore
Dapiprazolehsa01200Carbon metabolism2.23E-024P51854, P11413, P37837, P60891TKTL1, G6PD, TALDO1, PRPS1More
Dapiprazolehsa01230Biosynthesis of amino acids2.05E-045P51854, P60891, P05089, P15104, P37837TKTL1, PRPS1, ARG1, GLUL, TALDO1More
Dapiprazolehsa01523Antifolate resistance1.88E-034P41440, Q92820, P04818, P01375SLC19A1, GGH, TYMS, TNFMore
Dapiprazolehsa02010ABC transporters1.66E-043P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Dapiprazolehsa03010Ribosome2.25E-045P40429, Q07020, P27635, P05386, P62249RPL13A, RPL18, RPL10, RPLP1, RPS16More
Dapiprazolehsa03013RNA transport5.92E-0719O14980, P52298, Q09161, O14893, P61326, P38919, P37198, Q7Z3B4, P35658, P47813, Q14152, P55884, O75822, P78345, Q14240, Q9BZI7, Q9Y6A5, Q06787, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, EIF4A3, NUP62, NUP54, NUP214, EIF1AX, EIF3A, EIF3B, EIF3J, RPP38, EIF4A2, UPF3B, TACC3, FMR1, FXR1More
Dapiprazolehsa03020RNA polymerase3.03E-033P30876, P24928, P62487POLR2B, POLR2A, POLR2GMore
Dapiprazolehsa03022Basal transcription factors3.70E-054P20226, O00268, Q5H9L4, Q15544TBP, TAF4, TAF7L, TAF11More
Dapiprazolehsa03040Spliceosome2.03E-0813Q14562, O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, ASCC3L1More
Dapiprazolehsa03060Protein export6.23E-064Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Dapiprazolehsa03320PPAR signaling pathway3.64E-032Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Dapiprazolehsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Dapiprazolehsa03460Fanconi anemia pathway1.85E-022P40692, Q9UNA4MLH1, POLIMore
Dapiprazolehsa04012ErbB signaling pathway1.78E-035P16333, Q13191, P17252, P19174, P42338NCK1, CBLB, PRKCA, PLCG1, PIK3CBMore
Dapiprazolehsa04014Ras signaling pathway2.38E-0512P42338, P20827, Q9NRA1, P49767, Q13009, P17252, P14921, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, PRKCA, ETS1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Dapiprazolehsa04015Rap1 signaling pathway1.07E-0311P20827, P49767, P11215, P25116, Q8TEU7, Q13009, P42338, P0DP23, P08514, P17252, P19174EFNA1, VEGFC, ITGAM, F2R, RAPGEF6, TIAM1, PIK3CB, CALM1, ITGA2B, PRKCA, PLCG1More
Dapiprazolehsa04020Calcium signaling pathway4.34E-026P27987, P17252, O15399, P19174, P0DP23, P49767ITPKB, PRKCA, GRIN2D, PLCG1, CALM1, VEGFCMore
Dapiprazolehsa04022cGMP-PKG signaling pathway7.25E-046P24844, P18848, Q8WYR1, P05141, Q15746, P0DP24MYL9, ATF4, PIK3R5, SLC25A5, MYLK, CALM2More
Dapiprazolehsa04024cAMP signaling pathway4.83E-049P42338, P0DP23, Q13370, P48058, O15399, P25963, P25116, P24844, Q13009PIK3CB, CALM1, PDE3B, GRIA4, GRIN2D, NFKBIA, F2R, MYL9, TIAM1More
Dapiprazolehsa04060Cytokine-cytokine receptor interaction1.06E-0416P14784, P27930, P14778, P26842, Q06643, Q13651, Q9HBE5, P78552, P25024, Q9UBD3, P47992, O75509, P09341, P19875, P01730, Q93038IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, IL21R, IL13RA1, CXCR1, XCL2, XCL1, TNFRSF21, CXCL1, CXCL2, CD4, TNFRSF25More
Dapiprazolehsa04061Viral protein interaction with cytokine and cytokine receptor1.70E-038P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651, P14784CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RBMore
Dapiprazolehsa04062Chemokine signaling pathway1.51E-0718P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q08881, Q13009, P14598, P42224, P25963CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ITK, TIAM1, NCF1, STAT1, NFKBIAMore
Dapiprazolehsa04064NF-kappa B signaling pathway1.51E-1224P10415, Q13489, P25963, P51617, O00463, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Dapiprazolehsa04070Phosphatidylinositol signaling system4.13E-068P19174, P0DP23, P42338, P23743, Q86XP1, P27987, Q96DU7, P17252PLCG1, CALM1, PIK3CB, DGKA, DGKH, ITPKB, ITPKC, PRKCAMore
Dapiprazolehsa04071Sphingolipid signaling pathway6.39E-067P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, P10415PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, BCL2More
Dapiprazolehsa04072Phospholipase D signaling pathway5.17E-037P42338, Q92529, P43657, P25024, P25025, P19174, Q14344PIK3CB, SHC3, P2RY5, CXCR1, CXCR2, PLCG1, GNA13More
Dapiprazolehsa04080Neuroactive ligand-receptor interaction8.77E-0510P08311, P28472, Q15722, P21453, Q9H228, O00398, P21462, P21730, Q16581, P07550CTSG, GABRB3, LTB4R, S1PR1, EDG8, P2RY10, FPR1, C5AR1, C3AR1, ADRB2More
Dapiprazolehsa04110Cell cycle6.63E-046P06493, O60566, P30304, P33981, P42773, P01106CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYCMore
Dapiprazolehsa04114Oocyte meiosis2.22E-075Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Dapiprazolehsa04115p53 signaling pathway3.32E-035P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Dapiprazolehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Dapiprazolehsa04137Mitophagy - animal1.41E-033P67870, P19532, P18848CSNK2B, TFE3, ATF4More
Dapiprazolehsa04140Autophagy - animal1.56E-024Q9Y4H2, P42338, Q9NQL2, Q04759IRS2, PIK3CB, RRAGD, PRKCQMore
Dapiprazolehsa04141Protein processing in endoplasmic reticulum8.60E-036P30101, P60604, P11142, P08238, Q9H173, Q9UNL2PDIA3, UBE2G2, HSPA8, HSP90AB1, SIL1, SSR3More
Dapiprazolehsa04142Lysosome2.03E-0411Q99437, P08311, P25774, P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916, Q9UPM8ATP6V0B, CTSG, CTSS, HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2, AP4E1More
Dapiprazolehsa04144Endocytosis1.13E-0314Q13191, P0DMV8, P11142, Q9H444, O75351, P62491, P25024, Q96B97, P43250, Q15438, Q14161, P14784, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, PSCD1, GIT2, IL2RB, SNX12, SNX5More
Dapiprazolehsa04145Phagosome6.54E-0613P11215, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, Q99437, P05164, O60603, P35443, P13765, P25774ITGAM, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, ATP6V0B, MPO, TLR2, THBS4, HLA-DOB, CTSSMore
Dapiprazolehsa04146Peroxisome4.83E-024O96011, P56589, Q9UKG9, O75521PEX11B, PEX3, CROT, ECI2More
Dapiprazolehsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Dapiprazolehsa04151PI3K-Akt signaling pathway5.43E-0419P62753, P42338, O43521, P27348, P20827, P49767, P08238, Q8WYR1, P62873, P50151, P16144, O15335, Q13751, P14784, P01568, P18848, P17252, O00141, Q6ZUJ8RPS6, PIK3CB, BCL2L11, YWHAQ, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNB1, GNG10, ITGB4, CHAD, LAMB3, IL2RB, IFNA21, ATF4, PRKCA, SGK, PIK3AP1More
Dapiprazolehsa04210Apoptosis1.33E-0414Q13315, P10415, Q13489, O76075, P25963, P01375, O75460, P24522, Q16548, Q13077, O43521, P43234, P18848, Q14643ATM, BCL2, BIRC3, DFFB, NFKBIA, TNF, ERN1, GADD45A, BCL2A1, TRAF1, BCL2L11, CTSO, ATF4, ITPR1More
Dapiprazolehsa04213Longevity regulating pathway - multiple species1.29E-047P42338, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547PIK3CB, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Dapiprazolehsa04217Necroptosis5.23E-0618P01375, P01568, P23458, P48023, Q13489, Q9NQC7, P42224, Q14765, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, Q9H444, O43633, O75351TNF, IFNA21, JAK1, FASLG, BIRC3, CYLD, STAT1, STAT4, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, CHMP4B, CHMP2A, VPS4BMore
Dapiprazolehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Dapiprazolehsa04270Vascular smooth muscle contraction6.60E-048Q15746, P24844, P0DP23, Q08828, P51828, P35579, P35749, P35318MYLK, MYL9, CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Dapiprazolehsa04330Notch signaling pathway4.84E-042Q92542, P49768NCSTN, PSEN1More
Dapiprazolehsa04360Axon guidance1.16E-047P16333, P20827, O95631, P17252, P42338, P23528, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, CFL1, PLCG1More
Dapiprazolehsa04370VEGF signaling pathway1.92E-116P19174, P16298, P42338, P17252, Q05397, Q02750PLCG1, PPP3CB, PIK3CB, PRKCA, PTK2, MAP2K1More
Dapiprazolehsa04371Apelin signaling pathway7.95E-047P62873, P63218, P50151, Q13370, Q14344, P84022, P0DP23GNB1, GNG5, GNG10, PDE3B, GNA13, SMAD3, CALM1More
Dapiprazolehsa04380Osteoclast differentiation1.02E-026Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2More
Dapiprazolehsa04510Focal adhesion1.13E-0312P16144, P08514, O75369, Q15746, P24844, P42338, Q15942, P17252, O15335, Q13751, Q13489, P49767ITGB4, ITGA2B, FLNB, MYLK, MYL9, PIK3CB, ZYX, PRKCA, CHAD, LAMB3, BIRC3, VEGFCMore
Dapiprazolehsa04512ECM-receptor interaction2.44E-022P07359, P08514GP1BA, ITGA2BMore
Dapiprazolehsa04514Cell adhesion molecules4.65E-022P16109, O00501SELP, CLDN5More
Dapiprazolehsa04530Tight junction1.14E-046Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Dapiprazolehsa04540Gap junction1.08E-024Q13509, P68371, Q71U36, Q9NRA1TUBB3, TUBB2C, TUBA1A, PDGFCMore
Dapiprazolehsa04550Signaling pathways regulating pluripotency of stem cells4.73E-023Q13873, Q02750, Q86SE9BMPR2, MAP2K1, PCGF5More
Dapiprazolehsa04610Complement and coagulation cascades7.68E-063P25116, P0C0L4, P10909F2R, C4A, CLUMore
Dapiprazolehsa04611Platelet activation1.59E-055P25116, P08514, Q15746, Q8WYR1, P07359F2R, ITGA2B, MYLK, PIK3R5, GP1BAMore
Dapiprazolehsa04612Antigen processing and presentation1.88E-0813P13765, P48382, P01730, Q14953, P26715, P26717, Q07444, Q13241, O43908, P01732, P30101, P11142, P01375HLA-DOB, RFX5, CD4, KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, PDIA3, HSPA8, TNFMore
Dapiprazolehsa04613Neutrophil extracellular trap formation5.87E-0620P17252, O60603, P05164, P08246, Q9UM07, P04908, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, C5AR1, FPR1, AQP9, MAPK14More
Dapiprazolehsa04621NOD-like receptor signaling pathway2.63E-0516Q14643, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, P29728, Q05823, P01375, P09341, P49913, P59665, P59666, P12838ITPR1, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Dapiprazolehsa04623Cytosolic DNA-sensing pathway6.17E-054P01584, P01568, P25963, Q8NHW4IL1B, IFNA21, NFKBIA, CCL4L2More
Dapiprazolehsa04625C-type lectin receptor signaling pathway3.87E-024Q9ULY5, P20749, P01375, Q16539CLEC4E, BCL3, TNF, MAPK14More
Dapiprazolehsa04640Hematopoietic cell lineage1.52E-0813P13612, P14778, P27930, P11215, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375ITGA4, IL1R1, IL1R2, ITGAM, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNFMore
Dapiprazolehsa04650Natural killer cell mediated cytotoxicity2.00E-1717P16298, P50591, P19174, P01375, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Dapiprazolehsa04657IL-17 signaling pathway1.46E-048O00463, Q16539, P49841, P09341, P19875, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNFMore
Dapiprazolehsa04658Th1 and Th2 cell differentiation5.28E-1813Q04759, P07766, P20963, P09693, P19174, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, Q13761PRKCQ, CD3E, CD247, CD3G, PLCG1, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Dapiprazolehsa04659Th17 cell differentiation9.94E-2019P25963, Q04759, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, P84022, Q13485, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247More
Dapiprazolehsa04660T cell receptor signaling pathway1.73E-1116P01375, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P07766, P20963, P09693, P01730, P01732, Q13191, P06239TNF, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCKMore
Dapiprazolehsa04662B cell receptor signaling pathway2.26E-035P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Dapiprazolehsa04664Fc epsilon RI signaling pathway4.05E-059P01375, P04141, Q16539, P42338, P17252, Q9UQC2, P07948, P19174, P09917TNF, CSF2, MAPK14, PIK3CB, PRKCA, GAB2, LYN, PLCG1, ALOX5More
Dapiprazolehsa04666Fc gamma R-mediated phagocytosis6.80E-045P42338, P19174, P23528, P14598, P17252PIK3CB, PLCG1, CFL1, NCF1, PRKCAMore
Dapiprazolehsa04668TNF signaling pathway1.99E-0512P01375, O00463, Q13489, Q16539, P25963, P18848, P19875, P01584, P20749, Q13077, P14780, P20333TNF, TRAF5, BIRC3, MAPK14, NFKBIA, ATF4, CXCL2, IL1B, BCL3, TRAF1, MMP9, TNFRSF1BMore
Dapiprazolehsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Dapiprazolehsa04713Circadian entrainment7.16E-046O15399, P0DP23, P17252, P62873, P63218, P50151GRIN2D, CALM1, PRKCA, GNB1, GNG5, GNG10More
Dapiprazolehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Dapiprazolehsa04720Long-term potentiation1.12E-065P16298, Q15418, P51812, P18848, Q02750PPP3CB, RPS6KA1, RPS6KA3, ATF4, MAP2K1More
Dapiprazolehsa04722Neurotrophin signaling pathway1.98E-035Q05655, P49841, O43524, P48023, P52566PRKCD, GSK3B, FOXO3, FASLG, ARHGDIBMore
Dapiprazolehsa04724Glutamatergic synapse1.26E-079P48058, O15399, P51828, P17252, P62873, P63218, P50151, P15104, Q9NSB8GRIA4, GRIN2D, ADCY7, PRKCA, GNB1, GNG5, GNG10, GLUL, HOMER2More
Dapiprazolehsa04725Cholinergic synapse4.96E-038P22694, Q14643, P17252, P62873, P50151, P18848, P42338, P10415PRKACB, ITPR1, PRKCA, GNB1, GNG10, ATF4, PIK3CB, BCL2More
Dapiprazolehsa04726Serotonergic synapse2.52E-036P17252, P62873, P63218, P50151, P33260, P09917PRKCA, GNB1, GNG5, GNG10, CYP2C18, ALOX5More
Dapiprazolehsa04727GABAergic synapse4.07E-066P51828, P62873, P63218, P50151, P15104, P17252ADCY7, GNB1, GNG5, GNG10, GLUL, PRKCAMore
Dapiprazolehsa04730Long-term depression6.53E-032Q14344, P07948GNA13, LYNMore
Dapiprazolehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Dapiprazolehsa04742Taste transduction1.01E-021P30939HTR1FMore
Dapiprazolehsa04744Phototransduction1.59E-042P62873, P0DP23GNB1, CALM1More
Dapiprazolehsa04750Inflammatory mediator regulation of TRP channels6.44E-069P14778, P01584, Q08828, P51828, P19174, P42338, P24723, Q04759, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1More
Dapiprazolehsa04810Regulation of actin cytoskeleton1.38E-034P24844, Q15746, P08514, P25116MYL9, MYLK, ITGA2B, F2RMore
Dapiprazolehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Dapiprazolehsa04914Progesterone-mediated oocyte maturation1.19E-089Q17RY0, P42338, Q13370, Q9UJX4, Q9Y6D9, P30304, P08238, P51812, Q02750CPEB4, PIK3CB, PDE3B, ANAPC5, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1More
Dapiprazolehsa04915Estrogen signaling pathway2.77E-0310P14780, P22694, P18848, Q08828, P51828, P0DMV8, Q14643, P0DP23, Q15788, P10415MMP9, PRKACB, ATF4, ADCY1, ADCY7, HSPA1A, ITPR1, CALM1, NCOA1, BCL2More
Dapiprazolehsa04918Thyroid hormone synthesis1.26E-024P22694, P18848, Q14643, P05543PRKACB, ATF4, ITPR1, SERPINA7More
Dapiprazolehsa04919Thyroid hormone signaling pathway3.71E-022P26678, P08237PLN, PFKMMore
Dapiprazolehsa04920Adipocytokine signaling pathway4.49E-024P25963, P33121, Q04759, P01375NFKBIA, ACSL1, PRKCQ, TNFMore
Dapiprazolehsa04921Oxytocin signaling pathway6.37E-033Q15746, P24844, Q8WYR1MYLK, MYL9, PIK3R5More
Dapiprazolehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Dapiprazolehsa04924Renin secretion2.98E-034P22694, P07550, Q13370, P0DP23PRKACB, ADRB2, PDE3B, CALM1More
Dapiprazolehsa04926Relaxin signaling pathway1.10E-0310P25963, P42338, P62873, P50151, P18848, P22694, P49767, P14780, P17252, P30679NFKBIA, PIK3CB, GNB1, GNG10, ATF4, PRKACB, VEGFC, MMP9, PRKCA, GNA15More
Dapiprazolehsa04927Cortisol synthesis and secretion4.44E-043Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Dapiprazolehsa04928Parathyroid hormone synthesis, secretion and action2.13E-025Q14643, P22694, P23771, P18848, P10415ITPR1, PRKACB, GATA3, ATF4, BCL2More
Dapiprazolehsa04930Type II diabetes mellitus2.68E-021Q05655PRKCDMore
Dapiprazolehsa04932Non-alcoholic fatty liver disease6.81E-0712P01375, P49841, O43521, P18848, P48023, O75460, P01584, P13073, P12074, Q16718, O95298, O14521TNF, GSK3B, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA5, NDUFC2, SDHDMore
Dapiprazolehsa04933AGE-RAGE signaling pathway in diabetic complications3.43E-025P42224, P42338, P49767, P17252, P19174STAT1, PIK3CB, VEGFC, PRKCA, PLCG1More
Dapiprazolehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Dapiprazolehsa04960Aldosterone-regulated sodium reabsorption4.38E-021P48048KCNJ1More
Dapiprazolehsa04961Endocrine and other factor-regulated calcium reabsorption2.68E-023P20020, Q9UEF7, P17252ATP2B1, KL, PRKCAMore
Dapiprazolehsa04964Proximal tubule bicarbonate reclamation2.17E-031P00918CA2More
Dapiprazolehsa04966Collecting duct acid secretion2.17E-031P00918CA2More
Dapiprazolehsa04970Salivary secretion3.57E-048P07550, Q08828, P51828, P22694, Q14643, P17252, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, CALM1, CAMPMore
Dapiprazolehsa04972Pancreatic secretion2.68E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Dapiprazolehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Dapiprazolehsa04976Bile secretion3.14E-035O43315, Q08828, P51828, P08183, Q14032AQP9, ADCY1, ADCY7, ABCB1, BAATMore
Dapiprazolehsa05010Alzheimer disease2.91E-037P13073, O75460, P0DP24, P01584, P18848, P67870, P05141COX4I1, ERN1, CALM2, IL1B, ATF4, CSNK2B, SLC25A5More
Dapiprazolehsa05012Parkinson disease3.44E-0311P13073, P05141, P60604, O75460, P18848, P19174, P0DP23, P0DP24, Q71U36, Q13509, P68371COX4I1, SLC25A5, UBE2G2, ERN1, ATF4, PLCG1, CALM1, CALM2, TUBA1A, TUBB3, TUBB2CMore
Dapiprazolehsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Dapiprazolehsa05016Huntington disease3.74E-0310O95298, P13073, P12074, P24928, P30876, P62487, P05141, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4, PSMD12More
Dapiprazolehsa05017Spinocerebellar ataxia2.22E-024Q92915, O15399, P42338, P21796FGF14, GRIN2D, PIK3CB, VDAC1More
Dapiprazolehsa05020Prion disease4.42E-0410Q16718, O14521, P13073, Q92736, P18848, P05141, O60282, P49841, P67870, Q16539NDUFA5, SDHD, COX4I1, RYR2, ATF4, SLC25A5, KIF5C, GSK3B, CSNK2B, MAPK14More
Dapiprazolehsa05022Pathways of neurodegeneration - multiple diseases6.94E-0413P49841, Q16718, O14521, P13073, O75460, P18848, Q13561, P05141, P20333, Q16539, P01584, Q08752, P0DP24GSK3B, NDUFA5, SDHD, COX4I1, ERN1, ATF4, DCTN2, SLC25A5, TNFRSF1B, MAPK14, IL1B, PPID, CALM2More
Dapiprazolehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Dapiprazolehsa05032Morphine addiction7.16E-046P62873, P63218, P50151, Q13370, P17252, P43250GNB1, GNG5, GNG10, PDE3B, PRKCA, GRK6More
Dapiprazolehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Dapiprazolehsa05100Bacterial invasion of epithelial cells3.14E-033Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Dapiprazolehsa05110Vibrio cholerae infection4.65E-034Q13488, Q99437, P17252, P19174TCIRG1, ATP6V0B, PRKCA, PLCG1More
Dapiprazolehsa05120Epithelial cell signaling in Helicobacter pylori infection9.30E-079Q16539, P25963, Q13488, P09341, P19875, P19174, P25024, P25025, P07948MAPK14, NFKBIA, TCIRG1, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, LYNMore
Dapiprazolehsa05130Pathogenic Escherichia coli infection4.93E-0412Q71U36, Q14247, O00501, P16333, Q13509, P68371, P25116, Q14344, P25963, Q15438, P35579, P55061TUBA1A, CTTN, CLDN5, NCK1, TUBB3, TUBB2C, F2R, GNA13, NFKBIA, PSCD1, MYH9, TEGTMore
Dapiprazolehsa05131Shigellosis8.18E-0418P01375, P25963, O00463, Q05655, Q04759, Q9UDY8, Q9NQL2, Q9H1Y0, P0CG47, Q14141, Q96JJ3, Q05397, Q14643, Q12778, Q13315, P10415, Q96A32, P07737TNF, NFKBIA, TRAF5, PRKCD, PRKCQ, MALT1, RRAGD, ATG5, UBB, SEPT6, ELMO2, PTK2, ITPR1, FOXO1, ATM, BCL2, MYLPF, PFN1More
Dapiprazolehsa05132Salmonella infection1.20E-0521P51617, P25963, P01375, P08238, Q9UJU2, P84095, O00471, Q13546, Q13489, P10415, O75369, P07737, Q96A32, O60603, Q9BQS8, Q13561, O60282, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, LEF1, RHOG, EXOC5, RIPK1, BIRC3, BCL2, FLNB, PFN1, MYLPF, TLR2, FYCO1, DCTN2, KIF5C, TUBA1A, TUBB3, TUBB2C, VPS41More
Dapiprazolehsa05133Pertussis3.02E-031P0C0L4C4AMore
Dapiprazolehsa05134Legionellosis1.77E-068P01584, P25963, Q9NR31, P11215, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, HSPA1A, HSPA8, CXCL1, CXCL2More
Dapiprazolehsa05135Yersinia infection4.28E-048Q05397, P51812, P06239, P19174, Q02750, P42338, Q96JJ3, P01732PTK2, RPS6KA3, LCK, PLCG1, MAP2K1, PIK3CB, ELMO2, CD8AMore
Dapiprazolehsa05140Leishmaniasis1.31E-0412O75015, P14598, P11215, P42224, P13765, O60603, P25963, P01375, P49006, Q16539, P51617, Q15080FCGR3B, NCF1, ITGAM, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, MARCKSL1, MAPK14, IRAK1, NCF4More
Dapiprazolehsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Dapiprazolehsa05144Malaria1.94E-046P60033, P69905, P68871, P01375, P35443, P26718CD81, HBA2, HBB, TNF, THBS4, KLRK1More
Dapiprazolehsa05145Toxoplasmosis2.98E-0311P51617, P25963, P01375, P10415, Q13489, P42224, P13765, P09917, Q13751, P11142, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, STAT1, HLA-DOB, ALOX5, LAMB3, HSPA8, TLR2More
Dapiprazolehsa05146Amoebiasis7.74E-1313P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Dapiprazolehsa05150Staphylococcus aureus infection2.17E-0610P0C0L4, P21730, P21462, O75015, P13646, Q14532, P59665, P59666, P12838, P49913C4A, C5AR1, FPR1, FCGR3B, KRT13, KRT32, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Dapiprazolehsa05152Tuberculosis6.73E-0413Q13488, Q99437, P48382, P25208, O60603, P01375, P10415, P13765, P25774, P01568, P49913, Q9UDY8, P51617TCIRG1, ATP6V0B, RFX5, NFYB, TLR2, TNF, BCL2, HLA-DOB, CTSS, IFNA21, CAMP, MALT1, IRAK1More
Dapiprazolehsa05160Hepatitis C1.16E-036P52630, P60033, Q9NZJ5, P49841, P01375, P48023STAT2, CD81, EIF2AK3, GSK3B, TNF, FASLGMore
Dapiprazolehsa05161Hepatitis B2.33E-028P17252, P14780, P25963, P01375, P10415, P51617, O60603, Q14765PRKCA, MMP9, NFKBIA, TNF, BCL2, IRAK1, TLR2, STAT4More
Dapiprazolehsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Dapiprazolehsa05163Human cytomegalovirus infection2.48E-0724P42338, P01375, P25963, P62873, P63218, P50151, Q14643, P0DP23, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, P17252, Q13651, P25025, Q16539, P04637, O00463, P30101, P01568PIK3CB, TNF, NFKBIA, GNB1, GNG5, GNG10, ITPR1, CALM1, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, PRKCA, IL10RA, CXCR2, MAPK14, TP53, TRAF5, PDIA3, IFNA21More
Dapiprazolehsa05167Kaposi sarcoma-associated herpesvirus infection1.58E-0816P01568, P42224, P25963, P42338, P40189, P62873, P62879, P63218, P50151, P19174, P16298, Q02750, P07948, P04141, P0DP23, P0CG47IFNA21, STAT1, NFKBIA, PIK3CB, IL6ST, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, MAP2K1, LYN, CSF2, CALM1, UBBMore
Dapiprazolehsa05168Herpes simplex virus 1 infection4.09E-0513P25963, P01568, P42224, Q07955, Q01130, Q13243, Q13489, P30101, P42338, Q13398, Q03923, O75820, Q9UDV6NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, PIK3CB, ZNF211, ZNF85, ZNF189, ZNF212More
Dapiprazolehsa05169Epstein-Barr virus infection5.59E-0412P13765, P01106, Q13547, O00463, P07948, Q13761, P24522, P01375, P29728, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, LYN, RUNX3, GADD45A, TNF, OAS2, CD3E, CD3G, CD247More
Dapiprazolehsa05170Human immunodeficiency virus 1 infection4.13E-1028P42338, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, P01375, Q05397, P17252, Q13546, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P23528, P10415, Q13619, Q93034, Q9Y6Q5, P20333PIK3CB, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, RIPK1, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, CFL1, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Dapiprazolehsa05171Coronavirus disease - COVID-199.13E-0312P25963, P42224, P01568, P62249, P40429, P27635, Q07020, P05386, P40189, P42338, P19174, P17252NFKBIA, STAT1, IFNA21, RPS16, RPL13A, RPL10, RPL18, RPLP1, IL6ST, PIK3CB, PLCG1, PRKCAMore
Dapiprazolehsa05200Pathways in cancer1.78E-0725Q13751, P42338, P08238, P42224, P25963, P19174, P17252, P43246, P84022, P20585, P10826, P14923, Q13489, P49767, P14921, P62873, P63218, P50151, Q14344, P78417, O75293, P0DP23, P01568, P14784, P40189LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, PRKCA, MSH2, SMAD3, MSH3, RARB, JUP, BIRC3, VEGFC, ETS1, GNB1, GNG5, GNG10, GNA13, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Dapiprazolehsa05202Transcriptional misregulation in cancer1.20E-0718Q12778, Q15532, Q13315, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, Q13547, P24522FOXO1, SS18, ATM, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, HDAC1, GADD45AMore
Dapiprazolehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Dapiprazolehsa05204Chemical carcinogenesis1.09E-033P09211, P78417, P11712GSTP1, GSTO1, CYP2C9More
Dapiprazolehsa05205Proteoglycans in cancer2.02E-0312Q13009, Q14643, O75369, P14780, P17252, O60603, P01375, P23588, P04628, Q13635, P22694, P08962TIAM1, ITPR1, FLNB, MMP9, PRKCA, TLR2, TNF, EIF4B, WNT1, PTCH1, PRKACB, CD63More
Dapiprazolehsa05212Pancreatic cancer2.11E-034P42338, P42224, P84022, O75293PIK3CB, STAT1, SMAD3, GADD45BMore
Dapiprazolehsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Dapiprazolehsa05214Glioma1.89E-055P0DP23, P17252, P42338, P19174, O75293CALM1, PRKCA, PIK3CB, PLCG1, GADD45BMore
Dapiprazolehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Dapiprazolehsa05221Acute myeloid leukemia4.95E-023P42338, Q15744, P11215PIK3CB, CEBPE, ITGAMMore
Dapiprazolehsa05222Small cell lung cancer9.25E-0410P10826, P42338, Q13751, Q13489, P10415, P25963, Q13077, O00463, P24522, O75293RARB, PIK3CB, LAMB3, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A, GADD45BMore
Dapiprazolehsa05223Non-small cell lung cancer4.91E-035P17252, P42338, P19174, P10826, O75293PRKCA, PIK3CB, PLCG1, RARB, GADD45BMore
Dapiprazolehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Dapiprazolehsa05225Hepatocellular carcinoma1.85E-022Q92529, P51531SHC3, SMARCA2More
Dapiprazolehsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Dapiprazolehsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
Dapiprazolehsa05231Choline metabolism in cancer4.91E-035P42338, Q9Y259, P19174, P23743, P17252PIK3CB, CHKB, PLCG1, DGKA, PRKCAMore
Dapiprazolehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer2.22E-0811P42338, O95267, P19174, P07766, P20963, P09693, P06239, O60603, Q04759, Q16539, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14, CD4More
Dapiprazolehsa05310Asthma9.97E-043P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Dapiprazolehsa05321Inflammatory bowel disease7.33E-098O60603, P01375, P13765, Q14765, Q9UL17, P23771, P84022, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, SMAD3, IL21RMore
Dapiprazolehsa05322Systemic lupus erythematosus2.09E-0412P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P62807, O60814, P68431, P05455ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SSBMore
Dapiprazolehsa05323Rheumatoid arthritis4.95E-023Q06643, P09341, P19875LTB, CXCL1, CXCL2More
Dapiprazolehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Dapiprazolehsa05332Graft-versus-host disease1.89E-096P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Dapiprazolehsa05340Primary immunodeficiency2.62E-034P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Dapiprazolehsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Dapiprazolehsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore
Dapiprazolehsa05415Diabetic cardiomyopathy4.92E-035Q16718, O14521, Q16539, P49841, P11413NDUFA5, SDHD, MAPK14, GSK3B, G6PDMore
Dapiprazolehsa05418Fluid shear stress and atherosclerosis1.56E-0512Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Dapiprazole (SDC: 9.87)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P61073CXCR4CNoneXNoneC chemokine receptor type 4Predicted10.28230.40180.6481.5927
Q9UGN5PARP2Poly [ADPNoneribose] polymerase 2Predicted00.04350.26350.24610.7947
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
O95271TNKSPoly [ADPNoneribose] polymerase tankyraseNone1Predicted00.10170.222400.4957
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P09211GSTP1Glutathione SNonetransferase PPredicted00.32040.35230.45661.3213
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
Q13231CHIT1ChitotriosidaseNone1Predicted00.03570.04290.19630.3
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
P37840SNCAAlphaNonesynucleinPredicted10.08530.13240.33210.6395
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P25774CTSSCathepsin SPredicted00.31850.49320.51681.6625
P07948LYNTyrosineNoneprotein kinase LynPredicted00.0910.53190.6061.7154
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
Q15418RPS6KA1Ribosomal protein S6 kinase alphaNone1Predicted10.8320.32450.41461.4796
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
P05164MPOMyeloperoxidasePredicted10.20350.53680.55021.7255
O60502MGEA5Protein ONoneGlcNAcasePredicted00.51010.04550.10570.4517
P11511CYP19A1AromatasePredicted00.815610.15882.5666
Q9UDY8MALT1MucosaNoneassociated lymphoid tissue lymphoma translocation protein 1Predicted10.05160.1470.55920.8789
P01375TNFTumor necrosis factorPredicted10.18650.55112.1953
P08514ITGA2BIntegrin alphaNoneIIbPredicted10.07820.32480.7791.4677
P48048KCNJ1ATPNonesensitive inward rectifier potassium channel 1Predicted00.00420.2820.12740.6935
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P11413G6PDGlucoseNone6Nonephosphate 1NonedehydrogenasePredicted10.44350.63690.29291.7884
Q9NZJ5EIF2AK3Eukaryotic translation initiation factor 2Nonealpha kinase 3Predicted10.09390.15740.63981.0015
Q16513PKN2Serine/threonineNoneprotein kinase N2Predicted00.04210.27780.33910.9157
P24723PRKCHProtein kinase C eta typePredicted00.19550.32940.20480.9614
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
O95931CBX7Chromobox protein homolog 7Predicted00.41860.181600.5726
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
P49768PSEN1PresenilinNone1Predicted10.26770.65990.33081.7845
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
Q6PCB7SLC27A1LongNonechain fatty acid transport protein 1Predicted00.29150.07680.09920.3985
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)