PharmaCoNets
.
Dacarbazine
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PharmaCoNets of Dacarbazine (S
PCN
: 0.34 )
Dacarbazine regulated-network (S
DN
: 0.53)
Drug Name
Pathway ID
Pathway name
P-value
No. of gene members
UniProt AC
Gene name
Detail of Coexpression
Dacarbazine
hsa00030
Pentose phosphate pathway
1.09E-02
2
P52209, P37837
PGD, TALDO1
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
1
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P37837
TALDO1
Transaldolase
0.837
Dacarbazine
hsa04664
Fc epsilon RI signaling pathway
2.18E-02
2
P09917, P20292
ALOX5, ALOX5AP
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P09917
ALOX5
Polyunsaturated fatty acid 5-lipoxygenase
0.807
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P20292
ALOX5AP
Arachidonate 5-lipoxygenase-activating protein
0.853
Dacarbazine
hsa04962
Vasopressin-regulated water reabsorption
2.18E-02
2
P52566, P62491
ARHGDIB, RAB11A
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P52566
ARHGDIB
Rho GDP-dissociation inhibitor 2
0.847
P52209
PGD
6-phosphogluconate dehydrogenase, decarboxylating
P62491
RAB11A
Ras-related protein Rab-11A
0.719
Community members of Dacarbazine (S
DC
: 0.65)
UniProtAC
Gene Name
Protein Name
Reported/
Predicted
DisGeNET
S
PV
S
drugability
S
HiSBiN
S
DisG
P52209
PGD
6Nonephosphogluconate dehydrogenase, decarboxylating
Reported
0
0.195
0.1454
0.2642
0.6525
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
None
None
None
None
None
This pair is Reported in Drugbank.
Gene name
UniProt_ID
Bioactivity
Value (nM)
