| Crisaborole | hsa00040 | Pentose and glucuronate interconversions | 4.00E-02 | 1 | P15121 | AKR1B1 | More | |
| Crisaborole | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | |
| Crisaborole | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | |
| Crisaborole | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | |
| Crisaborole | hsa00790 | Folate biosynthesis | 2.02E-02 | 1 | P15121 | AKR1B1 | More | |
| Crisaborole | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 4.00E-02 | 1 | P09211 | GSTP1 | More | |
| Crisaborole | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | |
| Crisaborole | hsa03010 | Ribosome | 2.25E-04 | 5 | P40429, Q07020, P27635, P05386, P62249 | RPL13A, RPL18, RPL10, RPLP1, RPS16 | More | |
| Crisaborole | hsa03050 | Proteasome | 4.83E-02 | 1 | P55036 | PSMD4 | More | |
| Crisaborole | hsa04064 | NF-kappa B signaling pathway | 3.99E-02 | 6 | P10415, Q13489, P29965, Q9UDY8, Q8WV28, Q13315 | BCL2, BIRC3, CD40LG, MALT1, BLNK, ATM | More | |
| Crisaborole | hsa04070 | Phosphatidylinositol signaling system | 3.47E-02 | 4 | P0DP23, Q14643, P23743, P17252 | CALM1, ITPR1, DGKA, PRKCA | More | |
| Crisaborole | hsa04071 | Sphingolipid signaling pathway | 4.49E-02 | 4 | P17252, Q13362, Q9BX95, P10415 | PRKCA, PPP2R5C, SGPP1, BCL2 | More | |
| Crisaborole | hsa04137 | Mitophagy - animal | 1.41E-03 | 3 | P67870, P19532, P18848 | CSNK2B, TFE3, ATF4 | More | |
| Crisaborole | hsa04145 | Phagosome | 1.59E-03 | 7 | Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOB | More | |
| Crisaborole | hsa04151 | PI3K-Akt signaling pathway | 4.50E-02 | 9 | P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252 | F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCA | More | |
| Crisaborole | hsa04217 | Necroptosis | 9.14E-03 | 7 | P01568, Q13489, P42224, Q6FI13, P10415, O43633, Q08752 | IFNA21, BIRC3, STAT1, H2AC18; H2AC19, BCL2, CHMP2A, PPID | More | |
| Crisaborole | hsa04261 | Adrenergic signaling in cardiomyocytes | 2.84E-02 | 5 | P09493, Q13362, P0DP23, P17252, P10415 | TPM1, PPP2R5C, CALM1, PRKCA, BCL2 | More | |
| Crisaborole | hsa04310 | Wnt signaling pathway | 1.79E-02 | 2 | P17612, P67870 | PRKACA, CSNK2B | More | |
| Crisaborole | hsa04340 | Hedgehog signaling pathway | 3.91E-02 | 1 | P17612 | PRKACA | More | |
| Crisaborole | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | |
| Crisaborole | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | |
| Crisaborole | hsa04611 | Platelet activation | 2.12E-02 | 2 | Q9Y490, P17612 | TLN1, PRKACA | More | |
| Crisaborole | hsa04613 | Neutrophil extracellular trap formation | 3.58E-02 | 8 | P17252, O60603, P08246, Q6FI13, P68431, P14598, Q15080, P21462 | PRKCA, TLR2, ELA2, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1 | More | |
| Crisaborole | hsa04672 | Intestinal immune network for IgA production | 3.76E-03 | 3 | P29965, P10747, P13765 | CD40LG, CD28, HLA-DOB | More | |
| Crisaborole | hsa04713 | Circadian entrainment | 2.60E-02 | 4 | P0DP23, P17252, P62873, Q14643 | CALM1, PRKCA, GNB1, ITPR1 | More | |
| Crisaborole | hsa04720 | Long-term potentiation | 6.21E-03 | 5 | P17252, P0DP23, Q15418, P18848, Q14643 | PRKCA, CALM1, RPS6KA1, ATF4, ITPR1 | More | |
| Crisaborole | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | |
| Crisaborole | hsa04725 | Cholinergic synapse | 1.88E-02 | 4 | Q14643, P17252, P62873, P10415 | ITPR1, PRKCA, GNB1, BCL2 | More | |
| Crisaborole | hsa04728 | Dopaminergic synapse | 3.55E-02 | 5 | Q14643, P17252, P62873, Q13362, P0DP23 | ITPR1, PRKCA, GNB1, PPP2R5C, CALM1 | More | |
| Crisaborole | hsa04742 | Taste transduction | 3.91E-02 | 1 | P17612 | PRKACA | More | |
| Crisaborole | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | |
| Crisaborole | hsa04912 | GnRH signaling pathway | 3.89E-02 | 3 | P17252, Q14643, P0DP23 | PRKCA, ITPR1, CALM1 | More | |
| Crisaborole | hsa04918 | Thyroid hormone synthesis | 4.48E-02 | 2 | P18848, P05543 | ATF4, SERPINA7 | More | |
| Crisaborole | hsa04922 | Glucagon signaling pathway | 3.47E-02 | 4 | Q12778, Q13370, P0DP23, Q14643 | FOXO1, PDE3B, CALM1, ITPR1 | More | |
| Crisaborole | hsa04924 | Renin secretion | 8.71E-03 | 3 | Q14643, Q13370, P0DP23 | ITPR1, PDE3B, CALM1 | More | |
| Crisaborole | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.27E-02 | 5 | P42224, P10415, Q12778, P49767, P17252 | STAT1, BCL2, FOXO1, VEGFC, PRKCA | More | |
| Crisaborole | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | |
| Crisaborole | hsa04966 | Collecting duct acid secretion | 2.07E-03 | 3 | Q13488, P00918, Q9Y666 | TCIRG1, CA2, SLC12A7 | More | |
| Crisaborole | hsa05010 | Alzheimer disease | 1.02E-02 | 11 | Q16718, O14521, P13073, Q14643, P0DP23, P18848, Q13509, P68371, P67870, P05141, Q08752 | NDUFA5, SDHD, COX4I1, ITPR1, CALM1, ATF4, TUBB3, TUBB2C, CSNK2B, SLC25A5, PPID | More | |
| Crisaborole | hsa05012 | Parkinson disease | 2.25E-02 | 6 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C | More | |
| Crisaborole | hsa05020 | Prion disease | 4.67E-03 | 11 | Q16718, O14521, P13073, Q14643, P18848, P05141, Q13509, P68371, P67870, P14598, Q15080 | NDUFA5, SDHD, COX4I1, ITPR1, ATF4, SLC25A5, TUBB3, TUBB2C, CSNK2B, NCF1, NCF4 | More | |
| Crisaborole | hsa05022 | Pathways of neurodegeneration - multiple diseases | 4.48E-03 | 10 | Q14643, Q13509, P68371, P10415, Q16718, O14521, Q13561, P17252, Q08752, P0DP23 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, SDHD, DCTN2, PRKCA, PPID, CALM1 | More | |
| Crisaborole | hsa05110 | Vibrio cholerae infection | 2.11E-03 | 2 | Q99437, P17612 | ATP6V0B, PRKACA | More | |
| Crisaborole | hsa05130 | Pathogenic Escherichia coli infection | 4.08E-02 | 3 | Q15438, P35579, P55061 | PSCD1, MYH9, TEGT | More | |
| Crisaborole | hsa05131 | Shigellosis | 2.27E-02 | 8 | P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID | More | |
| Crisaborole | hsa05132 | Salmonella infection | 1.11E-02 | 8 | Q9UJU2, Q13489, P10415, O60603, Q9BQS8, Q13561, Q13509, P68371 | LEF1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, TUBB3, TUBB2C | More | |
| Crisaborole | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | |
| Crisaborole | hsa05140 | Leishmaniasis | 2.17E-03 | 6 | P14598, P42224, P13765, O60603, P29350, Q15080 | NCF1, STAT1, HLA-DOB, TLR2, PTPN6, NCF4 | More | |
| Crisaborole | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | |
| Crisaborole | hsa05144 | Malaria | 3.09E-02 | 2 | P69905, P68871 | HBA2, HBB | More | |
| Crisaborole | hsa05145 | Toxoplasmosis | 1.11E-02 | 6 | P10415, Q13489, P42224, P13765, O60603, P29965 | BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | |
| Crisaborole | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | |
| Crisaborole | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | |
| Crisaborole | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 4.73E-02 | 6 | P01568, P42224, P62873, Q14643, P0DP23, Q9UJU2 | IFNA21, STAT1, GNB1, ITPR1, CALM1, LEF1 | More | |
| Crisaborole | hsa05170 | Human immunodeficiency virus 1 infection | 4.67E-03 | 9 | P62873, P0DP23, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5 | GNB1, CALM1, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2 | More | |
| Crisaborole | hsa05171 | Coronavirus disease - COVID-19 | 3.87E-04 | 5 | P62249, P40429, P27635, Q07020, P05386 | RPS16, RPL13A, RPL10, RPL18, RPLP1 | More | |
| Crisaborole | hsa05200 | Pathways in cancer | 4.99E-02 | 12 | P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568 | STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21 | More | |
| Crisaborole | hsa05204 | Chemical carcinogenesis | 4.00E-02 | 1 | P09211 | GSTP1 | More | |
| Crisaborole | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | |
| Crisaborole | hsa05322 | Systemic lupus erythematosus | 4.18E-03 | 7 | P08246, P09871, P10747, P13765, P29965, Q6FI13, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | |
| Crisaborole | hsa05323 | Rheumatoid arthritis | 1.29E-02 | 4 | P13765, Q13488, P10747, O60603 | HLA-DOB, TCIRG1, CD28, TLR2 | More | |
| Crisaborole | hsa05330 | Allograft rejection | 1.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | |
| Crisaborole | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | |
| Crisaborole | hsa05415 | Diabetic cardiomyopathy | 3.55E-02 | 5 | P17252, P14598, Q15080, Q16718, O14521 | PRKCA, NCF1, NCF4, NDUFA5, SDHD | More | |
| Crisaborole | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | |
