PharmaCoNets of Clotrimazole (SPCN: 273.84 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Clotrimazolehsa00010Glycolysis / Gluconeogenesis1.89E-035P04075, P14550, P11766, P07195, P60174ALDOA, AKR1A1, ADH5, LDHB, TPI1More
Clotrimazolehsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Clotrimazolehsa00030Pentose phosphate pathway1.32E-134P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Clotrimazolehsa00040Pentose and glucuronate interconversions6.04E-043P15121, O60701, P14550AKR1B1, UGDH, AKR1A1More
Clotrimazolehsa00051Fructose and mannose metabolism2.63E-055P15121, P19367, P08237, P60174, P04075AKR1B1, HK1, PFKM, TPI1, ALDOAMore
Clotrimazolehsa00052Galactose metabolism1.02E-066P06280, P08237, O43451, P15121, P19367, Q14376GLA, PFKM, MGAM, AKR1B1, HK1, GALEMore
Clotrimazolehsa00071Fatty acid degradation2.44E-045P11310, O75521, P00325, P11766, P33121ACADM, ECI2, ADH1B, ADH5, ACSL1More
Clotrimazolehsa00100Steroid biosynthesis3.94E-021P35610SOAT1More
Clotrimazolehsa00190Oxidative phosphorylation1.23E-054Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Clotrimazolehsa00220Arginine biosynthesis7.66E-073P15104, P05089, P49448GLUL, ARG1, GLUD2More
Clotrimazolehsa00230Purine metabolism3.67E-033Q7LG56, P51828, Q9Y227RRM2B, ADCY7, ENTPD4More
Clotrimazolehsa00240Pyrimidine metabolism6.67E-044Q7LG56, P31350, Q9Y227, P04818RRM2B, RRM2, ENTPD4, TYMSMore
Clotrimazolehsa00250Alanine, aspartate and glutamate metabolism6.84E-053Q96RQ9, P49448, P15104IL4I1, GLUD2, GLULMore
Clotrimazolehsa00270Cysteine and methionine metabolism2.39E-022Q96RQ9, P40926IL4I1, MDH2More
Clotrimazolehsa00280Valine, leucine and isoleucine degradation4.33E-057P55809, Q9HCC0, P26440, Q96RQ9, P05166, Q02252, P11310OXCT1, MCCC2, IVD, IL4I1, PCCB, ALDH6A1, ACADMMore
Clotrimazolehsa00310Lysine degradation2.14E-057Q9NVH6, Q96KQ7, Q8NEZ4, Q13029, O15047, Q02809, P51648TMLHE, EHMT2, MLL3, PRDM2, SETD1A, PLOD1, ALDH3A2More
Clotrimazolehsa00330Arginine and proline metabolism2.73E-021P17707AMD1More
Clotrimazolehsa00380Tryptophan metabolism3.02E-021Q16613AANATMore
Clotrimazolehsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Clotrimazolehsa00471D-Glutamine and D-glutamate metabolism1.54E-032Q7Z3D6, P49448C14orf159, GLUD2More
Clotrimazolehsa00500Starch and sucrose metabolism1.40E-104O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Clotrimazolehsa00510N-Glycan biosynthesis1.10E-034O94777, P15907, Q9BVK2, Q9NR34DPM2, ST6GAL1, ALG8, MAN1C1More
Clotrimazolehsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Clotrimazolehsa00513Various types of N-glycan biosynthesis4.83E-021Q9NR34MAN1C1More
Clotrimazolehsa00520Amino sugar and nucleotide sugar metabolism2.98E-053Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Clotrimazolehsa00531Glycosaminoglycan degradation3.78E-021P15586GNSMore
Clotrimazolehsa00533Glycosaminoglycan biosynthesis - keratan sulfate6.96E-041Q9NY97B3GNT2More
Clotrimazolehsa00561Glycerolipid metabolism7.94E-033P15121, P14550, Q86XP1AKR1B1, AKR1A1, DGKHMore
Clotrimazolehsa00562Inositol phosphate metabolism4.54E-045Q9NRR6, P27987, O14732, P19174, P42338INPP5E, ITPKB, IMPA2, PLCG1, PIK3CBMore
Clotrimazolehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.28E-032O94777, Q14442DPM2, PIGHMore
Clotrimazolehsa00564Glycerophospholipid metabolism1.25E-046P48651, Q9Y6K0, P35790, P23743, O14494, Q3LIE5PTDSS1, CEPT1, CHKA, DGKA, PLPP1, ADPRMMore
Clotrimazolehsa00590Arachidonic acid metabolism2.48E-033P11712, P09917, P09960CYP2C9, ALOX5, LTA4HMore
Clotrimazolehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Clotrimazolehsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Clotrimazolehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Clotrimazolehsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.27E-072P06865, O75752HEXA, B3GALNT1More
Clotrimazolehsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Clotrimazolehsa00620Pyruvate metabolism9.80E-044P40926, P07195, P14550, P11766MDH2, LDHB, AKR1A1, ADH5More
Clotrimazolehsa00630Glyoxylate and dicarboxylate metabolism1.40E-094P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Clotrimazolehsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Clotrimazolehsa00670One carbon pool by folate2.35E-063O95954, P04818, Q99707FTCD, TYMS, MTRMore
Clotrimazolehsa00730Thiamine metabolism2.43E-062P05186, P24666ALPL, ACP1More
Clotrimazolehsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Clotrimazolehsa00750Vitamin B6 metabolism4.45E-021O00764PDXKMore
Clotrimazolehsa00770Pantothenate and CoA biosynthesis1.12E-054O95498, O95497, Q6ZQY3, Q9NRN7VNN2, VNN1, GADL1, AASDHPPTMore
Clotrimazolehsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Clotrimazolehsa00790Folate biosynthesis5.29E-044Q92820, P05186, P07101, P42330GGH, ALPL, TH, AKR1C3More
Clotrimazolehsa00830Retinol metabolism2.70E-065P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Clotrimazolehsa00860Porphyrin and chlorophyll metabolism9.12E-073P36551, P53004, P30043CPOX, BLVRA, BLVRBMore
Clotrimazolehsa00900Terpenoid backbone biosynthesis4.22E-022P49354, Q9UHG3FNTA, PCYOX1More
Clotrimazolehsa00910Nitrogen metabolism4.40E-032P15104, P49448GLUL, GLUD2More
Clotrimazolehsa00970Aminoacyl-tRNA biosynthesis8.98E-074O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Clotrimazolehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Clotrimazolehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Clotrimazolehsa00983Drug metabolism - other enzymes9.89E-085P04183, P20839, P32320, P05164, Q16772TK1, IMPDH1, CDA, MPO, GSTA3More
Clotrimazolehsa01040Biosynthesis of unsaturated fatty acids4.28E-021P22307SCP2More
Clotrimazolehsa01100Metabolic pathways8.01E-0769Q9NR34, Q9Y234, P35790, P05089, P21953, Q16772, Q9UJ14, P30041, P15104, P19367, P42338, Q9Y217, P48426, P27987, Q96DU7, P22557, Q6ZQY3, P32320, Q08828, Q02153, P20839, P22748, P40926, P55809, P06280, O94777, Q16875, O43286, O43451, P53004, Q9Y6K0, P05186, P24666, P15121, P08237, Q86XP1, O95861, Q96RQ9, Q9HCC0, P33121, Q9UHK6, Q86VZ5, Q96G23, P09917, P48651, Q9BVK2, P57054, Q14442, Q9UNP4, Q9H4F1, Q9BX95, Q9BRR6, P32321, P49448, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q969G6, P05166, P14927, P12074, P05496, Q99437, O15239, O15047, Q9NVH6MAN1C1, LIPT1, CHKA, ARG1, BCKDHB, GSTA3, GGTL3, PRDX6, GLUL, HK1, PIK3CB, MTMR6, PIP4K2A, ITPKB, ITPKC, ALAS2, GADL1, CDA, ADCY1, GUCY1B3, IMPDH1, CA4, MDH2, OXCT1, GLA, DPM2, PFKFB3, B4GALT5, MGAM, BLVRA, CEPT1, ALPL, ACP1, AKR1B1, PFKM, DGKH, BPNT1, IL4I1, MCCC2, ACSL1, AMACR, SGMS1, LASS2, ALOX5, PTDSS1, ALG8, PIGP, PIGH, ST3GAL5, ST6GALNAC4, SGPP1, ADPGK, DCTD, GLUD2, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, RFK, PCCB, UQCRB, COX6A1, ATP5G1, ATP6V0B, NDUFA1, SETD1A, TMLHEMore
Clotrimazolehsa01200Carbon metabolism7.14E-034P51854, P52209, P37837, P60891TKTL1, PGD, TALDO1, PRPS1More
Clotrimazolehsa012102-Oxocarboxylic acid metabolism6.96E-041P50213IDH3AMore
Clotrimazolehsa01212Fatty acid metabolism4.62E-022P33121, P11310ACSL1, ACADMMore
Clotrimazolehsa01230Biosynthesis of amino acids1.59E-066P51854, P60891, Q99707, P50213, P05089, P37837TKTL1, PRPS1, MTR, IDH3A, ARG1, TALDO1More
Clotrimazolehsa01240Biosynthesis of cofactors2.85E-047Q969G6, P13716, P36551, P22557, O60701, P14618, Q9Y234RFK, ALAD, CPOX, ALAS2, UGDH, PKM2, LIPT1More
Clotrimazolehsa01521EGFR tyrosine kinase inhibitor resistance3.18E-042P04049, P08069RAF1, IGF1RMore
Clotrimazolehsa01522Endocrine resistance2.90E-058P22694, P04049, Q9UM47, P04637, P42773, P08069, P10415, Q13323PRKACB, RAF1, NOTCH3, TP53, CDKN2C, IGF1R, BCL2, BIKMore
Clotrimazolehsa01523Antifolate resistance1.50E-065P41440, Q92820, P04818, P01375, P18054SLC19A1, GGH, TYMS, TNF, ALOX12More
Clotrimazolehsa01524Platinum drug resistance1.58E-0610Q13489, O15392, Q14790, P48023, P78417, P40692, P23025, P11388, P52701, P31751BIRC3, BIRC5, CASP8, FASLG, GSTO1, MLH1, XPA, TOP2A, MSH6, AKT2More
Clotrimazolehsa02010ABC transporters1.98E-033P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Clotrimazolehsa03008Ribosome biogenesis in eukaryotes1.88E-023O14980, O60832, Q9BVP2XPO1, DKC1, GNL3More
Clotrimazolehsa03010Ribosome1.11E-1224P26373, P62753, P42677, P25398, P32969, P30050, P40429, P62906, P62917, P46776, P46777, Q9H0U6, Q07020, P62899, P62910, P18077, P61927, Q02878, P36578, P27635, P50914, P05386, P62249, P23396RPL13, RPS6, RPS27, RPS12, RPL9, RPL12, RPL13A, RPL10A, RPL8, RPL27A, RPL5, MRPL18, RPL18, RPL31, RPL32, RPL35A, RPL37, RPL6, RPL4, RPL10, RPL14, RPLP1, RPS16, RPS3More
Clotrimazolehsa03013RNA transport4.82E-2530P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9H307, Q7Z3B4, P35658, P63279, P68104, P47813, O14602, Q14152, P55884, O15371, O75822, P78345, Q9H777, P11940, P20042, Q14240, Q9BZI7, P23588, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF1AY, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, ELAC1, PABPC1, EIF2S2, EIF4A2, UPF3B, EIF4B, TACC3, EIF2B1, FMR1, FXR1More
Clotrimazolehsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Clotrimazolehsa03018RNA degradation5.00E-021Q9NQT4EXOSC5More
Clotrimazolehsa03020RNA polymerase1.75E-126P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Clotrimazolehsa03022Basal transcription factors2.97E-033P20226, O00268, Q15544TBP, TAF4, TAF11More
Clotrimazolehsa03030DNA replication1.48E-023P49005, P33993, P15927POLD2, MCM7, RPA2More
Clotrimazolehsa03040Spliceosome1.09E-1315Q14562, O43143, O60508, P08579, P26368, O75940, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, SMNDC1, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Clotrimazolehsa03050Proteasome4.83E-021P55036PSMD4More
Clotrimazolehsa03060Protein export1.20E-104Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Clotrimazolehsa03320PPAR signaling pathway4.93E-034Q6PCB7, O00767, Q9UNU6, Q02318SLC27A1, SCD, CYP8B1, CYP27A1More
Clotrimazolehsa03430Mismatch repair4.38E-021P20585MSH3More
Clotrimazolehsa03450Non-homologous end-joining1.84E-031Q9NP87POLMMore
Clotrimazolehsa03460Fanconi anemia pathway8.90E-043P40692, O60673, Q9UNA4MLH1, REV3L, POLIMore
Clotrimazolehsa04010MAPK signaling pathway8.69E-054P04049, P08069, Q9H2K8, Q12933RAF1, IGF1R, TAOK3, TRAF2More
Clotrimazolehsa04012ErbB signaling pathway2.25E-067Q13153, P16333, Q13191, P19174, P42338, P01106, P04049PAK1, NCK1, CBLB, PLCG1, PIK3CB, MYC, RAF1More
Clotrimazolehsa04014Ras signaling pathway1.59E-0614P04049, P31751, P42338, P20827, Q9NRA1, P49767, P08069, Q13009, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174RAF1, AKT2, PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Clotrimazolehsa04015Rap1 signaling pathway5.10E-0715P04049, P20827, Q9NRA1, P49767, P08069, P06213, Q96FS4, P11215, Q13009, O00522, Q7LDG7, P42338, P31751, P0DP23, P19174RAF1, EFNA1, PDGFC, VEGFC, IGF1R, INSR, SIPA1, ITGAM, TIAM1, KRIT1, RASGRP2, PIK3CB, AKT2, CALM1, PLCG1More
Clotrimazolehsa04020Calcium signaling pathway1.06E-0919P27987, Q96DU7, Q08828, P21796, P45880, Q13557, P21860, P30679, P19174, P0DP24, P0DP23, P05141, P12236, P51828, P26678, P63092, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK2D, ERBB3, GNA15, PLCG1, CALM2, CALM1, SLC25A5, SLC25A6, ADCY7, PLN, GNAS, ATP2B4, PDGFC, VEGFCMore
Clotrimazolehsa04022cGMP-PKG signaling pathway4.73E-0915Q02153, P61586, P26678, P04049, Q99941, P18848, P23634, P31751, Q08828, P51828, P05141, P12236, P45880, P0DP24, P0DP23GUCY1B3, RHOA, PLN, RAF1, CREBL1, ATF4, ATP2B4, AKT2, ADCY1, ADCY7, SLC25A5, SLC25A6, VDAC2, CALM2, CALM1More
Clotrimazolehsa04024cAMP signaling pathway1.08E-046Q08828, P51828, P31751, P0DP23, P04049, Q13153ADCY1, ADCY7, AKT2, CALM1, RAF1, PAK1More
Clotrimazolehsa04060Cytokine-cytokine receptor interaction6.46E-0517P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, Q9HBE5, P78552, P25024, Q9UBD3, P47992, P09341, P19875, P80075, P01730, Q93038IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL21R, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CXCL2, CCL8, CD4, TNFRSF25More
Clotrimazolehsa04061Viral protein interaction with cytokine and cytokine receptor2.92E-0611Q8NHW4, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Clotrimazolehsa04062Chemokine signaling pathway5.86E-1224P25024, P25025, P09341, P19875, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q7LDG7, Q13009, P14598, P42224, P04049, P25963, P49841, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, RASGRP2, TIAM1, NCF1, STAT1, RAF1, NFKBIA, GSK3B, PIK3R5More
Clotrimazolehsa04064NF-kappa B signaling pathway1.07E-2125P10415, Q13489, P25963, P51617, O00463, Q13546, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Clotrimazolehsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Clotrimazolehsa04068FoxO signaling pathway4.41E-054P04049, P08069, P48023, Q96BR1RAF1, IGF1R, FASLG, SGK3More
Clotrimazolehsa04070Phosphatidylinositol signaling system2.43E-0611P19174, P0DP23, P42338, O14986, P23743, P49619, Q86XP1, Q16760, P48426, P27987, Q96DU7PLCG1, CALM1, PIK3CB, PIP5K1B, DGKA, DGKG, DGKH, DGKD, PIP4K2A, ITPKB, ITPKCMore
Clotrimazolehsa04071Sphingolipid signaling pathway5.50E-1012P04049, P17252, P21453, Q9H228, P01375, Q96G23, Q13362, Q9BX95, P10415, Q9UQC2, Q12933, Q02156RAF1, PRKCA, S1PR1, EDG8, TNF, LASS2, PPP2R5C, SGPP1, BCL2, GAB2, TRAF2, PRKCEMore
Clotrimazolehsa04072Phospholipase D signaling pathway2.30E-0616P04049, P31751, P42338, Q9UQC2, P43657, P25024, P25025, P19174, O14986, Q14344, Q15438, Q08828, P51828, P23743, Q16760, Q9NRA1RAF1, AKT2, PIK3CB, GAB2, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNA13, PSCD1, ADCY1, ADCY7, DGKA, DGKD, PDGFCMore
Clotrimazolehsa04080Neuroactive ligand-receptor interaction7.62E-1013P08311, P28472, P78334, Q15722, P21453, Q9H228, P43657, O00398, P21462, P21730, P30939, P07550, P35318CTSG, GABRB3, GABRE, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, FPR1, C5AR1, HTR1F, ADRB2, ADMMore
Clotrimazolehsa04110Cell cycle1.19E-0813Q9UBD5, P30260, P06493, O60566, Q14683, O75293, P04637, P49918, P30304, P33981, P42773, P01106, Q13547ORC3, CDC27, CDK1, BUB1B, SMC1A, GADD45B, TP53, CDKN1C, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Clotrimazolehsa04114Oocyte meiosis2.64E-1111Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Clotrimazolehsa04115p53 signaling pathway6.31E-048P24522, O15151, Q13315, P31350, Q53FA7, P06493, O95067, P10415GADD45A, MDM4, ATM, RRM2, TP53I3, CDK1, CCNB2, BCL2More
Clotrimazolehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Clotrimazolehsa04136Autophagy - other4.46E-052O94817, Q9H1Y0ATG12, ATG5More
Clotrimazolehsa04137Mitophagy - animal1.41E-033P67870, P19532, P18848CSNK2B, TFE3, ATF4More
Clotrimazolehsa04140Autophagy - animal6.94E-0715P08069, Q9Y4H2, P42338, P31751, P04049, Q7L523, Q9NQL2, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, IRS2, PIK3CB, AKT2, RAF1, RRAGA, RRAGD, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Clotrimazolehsa04141Protein processing in endoplasmic reticulum6.89E-0615P18848, Q12933, P30101, P07384, O95487, Q15436, P60604, Q99941, P11142, Q9H3Z4, P07900, P08238, Q9NR31, O95816, Q9UNL2ATF4, TRAF2, PDIA3, CAPN1, SEC24B, SEC23A, UBE2G2, CREBL1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, BAG2, SSR3More
Clotrimazolehsa04142Lysosome1.11E-0511O14773, P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, Q9NRA2, P49279, P61916, Q04900TPP1, HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC17A5, SLC11A1, NPC2, CD164More
Clotrimazolehsa04144Endocytosis8.76E-0719Q13191, P0DMV8, P11142, Q9H444, O43633, O75351, P62491, P25024, Q96B97, P43250, Q6WKZ4, Q15438, Q8WU79, Q14161, P14784, O95219, O75154, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, CHMP2A, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, RAB11FIP1, PSCD1, SMAP1L, GIT2, IL2RB, SNX4, RAB11FIP3, SNX12, SNX5More
Clotrimazolehsa04145Phagosome5.14E-0611O75015, Q15080, P14598, Q13509, P68371, Q13488, P05164, P78380, O60603, P35443, P13765FCGR3B, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Clotrimazolehsa04146Peroxisome1.95E-036O00623, O96011, P56589, Q9UKG9, O75521, P33121PEX12, PEX11B, PEX3, CROT, ECI2, ACSL1More
Clotrimazolehsa04150mTOR signaling pathway1.32E-035P08069, P04049, Q02750, Q9NQL2, P51812IGF1R, RAF1, MAP2K1, RRAGD, RPS6KA3More
Clotrimazolehsa04151PI3K-Akt signaling pathway4.47E-1038P62753, P42338, P21860, P43657, P01106, O43521, P04637, P27348, P20827, O14944, Q9NRA1, P49767, Q13362, P07900, P08238, Q15831, Q8WYR1, P62873, P63218, P50151, P61952, O15335, P02452, P24821, Q16363, Q13751, P22105, P14784, P23458, P01568, Q99941, P18848, Q96BR1, O00141, Q6ZUJ8, P30281, P56279, O95988RPS6, PIK3CB, ERBB3, P2RY5, MYC, BCL2L11, TP53, YWHAQ, EFNA1, EREG, PDGFC, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, STK11, PIK3R5, GNB1, GNG5, GNG10, GNG11, CHAD, COL1A1, TNC, LAMA4, LAMB3, TNXB, IL2RB, JAK1, IFNA21, CREBL1, ATF4, SGK3, SGK, PIK3AP1, CCND3, TCL1A, TCL1BMore
Clotrimazolehsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Clotrimazolehsa04210Apoptosis6.05E-0616Q13315, P10415, Q13489, O76075, P25963, Q14790, P01375, P48023, Q9NR28, P24522, Q16548, Q13077, P43234, Q14643, P42575, P04049ATM, BCL2, BIRC3, DFFB, NFKBIA, CASP8, TNF, FASLG, DIABLO, GADD45A, BCL2A1, TRAF1, CTSO, ITPR1, CASP2, RAF1More
Clotrimazolehsa04211Longevity regulating pathway2.60E-046P31751, P08069, Q08828, P51828, P18848, Q96RR4AKT2, IGF1R, ADCY1, ADCY7, ATF4, CAMKK2More
Clotrimazolehsa04213Longevity regulating pathway - multiple species2.09E-099P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Clotrimazolehsa04215Apoptosis - multiple species1.56E-022Q13489, P10415BIRC3, BCL2More
Clotrimazolehsa04217Necroptosis2.74E-1020P01375, Q12933, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, Q14765, P07900, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, Q13557, Q9H444, O75351, P45880TNF, TRAF2, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, CAMK2D, CHMP4B, VPS4B, VDAC2More
Clotrimazolehsa04218Cellular senescence3.45E-0511P01106, P31751, P04049, P30281, O75293, P30304, P06493, P0DP23, P01889, P10321, P12236MYC, AKT2, RAF1, CCND3, GADD45B, CDC25A, CDK1, CALM1, HLA-B, HLA-C, SLC25A6More
Clotrimazolehsa04260Cardiac muscle contraction4.20E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Clotrimazolehsa04261Adrenergic signaling in cardiomyocytes5.34E-1016P67936, P07550, P63092, Q08828, P51828, P22694, P31751, Q99941, P18848, P26678, Q13362, Q14738, P0DP24, P0DP23, Q13557, P23634TPM4, ADRB2, GNAS, ADCY1, ADCY7, PRKACB, AKT2, CREBL1, ATF4, PLN, PPP2R5C, PPP2R5D, CALM2, CALM1, CAMK2D, ATP2B4More
Clotrimazolehsa04270Vascular smooth muscle contraction3.12E-0711P24723, Q04759, Q14643, P0DP23, P04049, Q08828, P51828, P22694, P35579, P35749, P35318PRKCH, PRKCQ, ITPR1, CALM1, RAF1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Clotrimazolehsa04310Wnt signaling pathway2.28E-045P30279, Q13485, O43318, P17612, P67870CCND2, SMAD4, MAP3K7, PRKACA, CSNK2BMore
Clotrimazolehsa04330Notch signaling pathway4.54E-044Q92542, P49768, P46531, Q9UM47NCSTN, PSEN1, NOTCH1, NOTCH3More
Clotrimazolehsa04340Hedgehog signaling pathway5.38E-075P49841, P17612, P22694, Q13635, P10415GSK3B, PRKACA, PRKACB, PTCH1, BCL2More
Clotrimazolehsa04360Axon guidance1.16E-0614P16298, Q05397, P16333, P20827, O95631, Q13873, P42338, P07332, P23528, P04049, P19174, Q06124, O14639, P24844PPP3CB, PTK2, NCK1, EFNA1, NTN1, BMPR2, PIK3CB, FES, CFL1, RAF1, PLCG1, PTPN11, ABLIM1, MYL9More
Clotrimazolehsa04370VEGF signaling pathway5.06E-157P19174, P16298, P31751, P42338, Q05397, Q02750, P04049PLCG1, PPP3CB, AKT2, PIK3CB, PTK2, MAP2K1, RAF1More
Clotrimazolehsa04371Apelin signaling pathway8.00E-0817P62873, P63218, P50151, P61952, Q8WYR1, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P62753, P0DP23, P0DP24GNB1, GNG5, GNG10, GNG11, PIK3R5, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, RPS6, CALM1, CALM2More
Clotrimazolehsa04380Osteoclast differentiation2.23E-0914Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Clotrimazolehsa04390Hippo signaling pathway2.79E-079O95835, P63261, P84022, Q13485, O15105, P04628, Q9UJU2, O43623, Q13489LATS1, ACTG1, SMAD3, SMAD4, SMAD7, WNT1, LEF1, SNAI2, BIRC3More
Clotrimazolehsa04392Hippo signaling pathway - multiple species2.11E-053O95835, Q13153, Q6V0I7LATS1, PAK1, FAT4More
Clotrimazolehsa04510Focal adhesion1.63E-035Q15942, P51636, P30281, P04049, P08069ZYX, CAV2, CCND3, RAF1, IGF1RMore
Clotrimazolehsa04512ECM-receptor interaction2.77E-056P02452, P24821, P07359, P26012, P08514, P16070COL1A1, TNC, GP1BA, ITGB8, ITGA2B, CD44More
Clotrimazolehsa04520Adherens junction1.81E-033Q13485, O43318, P08069SMAD4, MAP3K7, IGF1RMore
Clotrimazolehsa04530Tight junction1.85E-059Q8TEU7, P63261, P16989, P56750, O00501, Q9Y478, Q92974, Q14247, P24844RAPGEF6, ACTG1, CSDA, CLDN17, CLDN5, PRKAB1, ARHGEF2, CTTN, MYL9More
Clotrimazolehsa04540Gap junction1.10E-046P22694, Q13509, P68371, P04049, Q9NRA1, Q14643PRKACB, TUBB3, TUBB2C, RAF1, PDGFC, ITPR1More
Clotrimazolehsa04550Signaling pathways regulating pluripotency of stem cells1.61E-035Q13873, P04049, Q02750, P08069, Q86SE9BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Clotrimazolehsa04610Complement and coagulation cascades1.45E-084P09871, P0C0L4, P20023, P05107C1S, C4A, CR2, ITGB2More
Clotrimazolehsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Clotrimazolehsa04612Antigen processing and presentation5.00E-1413P13765, P48382, P01730, Q14953, P26715, P26717, Q07444, Q13241, O43908, P01732, P30101, P11142, P01375HLA-DOB, RFX5, CD4, KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, PDIA3, HSPA8, TNFMore
Clotrimazolehsa04613Neutrophil extracellular trap formation5.30E-1336P42338, P19174, P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P04908, P0C0S5, Q6FI13, Q99878, Q93077, P58876, P62807, Q93079, Q16778, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539PIK3CB, PLCG1, PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AC4; H2AC8, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, H2BC5, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Clotrimazolehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Clotrimazolehsa04620Toll-like receptor signaling pathway6.81E-068Q13546, P01568, P01584, P31751, P42224, P25963, P42338, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, STAT1, NFKBIA, PIK3CB, CCL4L2More
Clotrimazolehsa04621NOD-like receptor signaling pathway3.13E-0518P01584, P07900, Q14643, P23458, P45880, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, P29728, Q05823, P01375, P09341, P49913, P12838IL1B, HSP90AA1, ITPR1, JAK1, VDAC2, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Clotrimazolehsa04622RIG-I-like receptor signaling pathway1.29E-075P01568, Q9NQC7, Q13546, Q12933, P10145IFNA21, CYLD, RIPK1, TRAF2, IL8More
Clotrimazolehsa04623Cytosolic DNA-sensing pathway3.28E-116P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Clotrimazolehsa04625C-type lectin receptor signaling pathway3.16E-1016Q9ULY5, P04049, Q13153, P01584, Q9NQC7, P42224, P20749, P25963, Q14643, P01375, Q13191, P42338, P31751, P0DP24, P0DP23, Q16539CLEC4E, RAF1, PAK1, IL1B, CYLD, STAT1, BCL3, NFKBIA, ITPR1, TNF, CBLB, PIK3CB, AKT2, CALM2, CALM1, MAPK14More
Clotrimazolehsa04630JAK-STAT signaling pathway1.01E-048P01106, P31751, P42224, P23458, P14784, P16871, Q13651, P04049MYC, AKT2, STAT1, JAK1, IL2RB, IL7R, IL10RA, RAF1More
Clotrimazolehsa04640Hematopoietic cell lineage2.18E-1320P13612, P07359, P08514, P21926, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P01584ITGA4, GP1BA, ITGA2B, CD9, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, IL1BMore
Clotrimazolehsa04650Natural killer cell mediated cytotoxicity4.03E-3120P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, P04049, Q13153, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, PAK1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Clotrimazolehsa04657IL-17 signaling pathway9.00E-1015P25963, P07900, P08238, O00463, Q12933, Q07955, Q16539, P49841, P09341, P19875, P14780, P80188, P01375, P06702, P01584NFKBIA, HSP90AA1, HSP90AB1, TRAF5, TRAF2, SFRS1, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNF, S100A9, IL1BMore
Clotrimazolehsa04658Th1 and Th2 cell differentiation1.81E-4018P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, Q9UM47, P13765, P23458, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, JAK1, RUNX3More
Clotrimazolehsa04659Th17 cell differentiation1.17E-3021P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Clotrimazolehsa04660T cell receptor signaling pathway1.75E-2820P01375, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, Q13153, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, PAK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Clotrimazolehsa04662B cell receptor signaling pathway1.66E-1414P25963, P31751, P42338, P20023, P60033, P13164, P16298, Q8WV28, P07948, P11912, P21854, Q8N149, Q02750, P04049NFKBIA, AKT2, PIK3CB, CR2, CD81, IFITM1, PPP3CB, BLNK, LYN, CD79A, CD72, LILRA2, MAP2K1, RAF1More
Clotrimazolehsa04664Fc epsilon RI signaling pathway5.50E-1010P01375, P31751, Q16539, P42338, Q9UQC2, P07948, P19174, P04049, P09917, P20292TNF, AKT2, MAPK14, PIK3CB, GAB2, LYN, PLCG1, RAF1, ALOX5, ALOX5APMore
Clotrimazolehsa04666Fc gamma R-mediated phagocytosis2.40E-038P08637, O75015, P07948, P42338, P19174, P04049, P06396, P14598FCGR3A, FCGR3B, LYN, PIK3CB, PLCG1, RAF1, GSN, NCF1More
Clotrimazolehsa04668TNF signaling pathway7.61E-0715P01375, Q12933, O00463, Q13489, Q16539, P25963, Q99941, P18848, P19875, P01584, P20749, Q13077, P14780, P20333, O95429TNF, TRAF2, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, ATF4, CXCL2, IL1B, BCL3, TRAF1, MMP9, TNFRSF1B, BAG4More
Clotrimazolehsa04670Leukocyte transendothelial migration6.23E-0311P14780, P11215, P60709, Q96A32, P17252, P14598, Q15080, Q08881, P42681, P19174, P12814MMP9, ITGAM, ACTB, MYLPF, PRKCA, NCF1, NCF4, ITK, TXK, PLCG1, ACTN1More
Clotrimazolehsa04710Circadian rhythm1.65E-033O15516, Q16526, Q9Y478CLOCK, CRY1, PRKAB1More
Clotrimazolehsa04713Circadian entrainment3.32E-0710P0DP23, P0DP24, Q13557, Q02153, P62873, P63218, P50151, P61952, Q08828, P51828CALM1, CALM2, CAMK2D, GUCY1B3, GNB1, GNG5, GNG10, GNG11, ADCY1, ADCY7More
Clotrimazolehsa04714Thermogenesis4.09E-057Q16539, P15336, P63261, P33121, Q9Y478, Q16718, O14521MAPK14, ATF2, ACTG1, ACSL1, PRKAB1, NDUFA5, SDHDMore
Clotrimazolehsa04720Long-term potentiation2.77E-1110Q13557, P16298, P0DP23, P0DP24, Q15418, P51812, P18848, Q08828, Q02750, P04049CAMK2D, PPP3CB, CALM1, CALM2, RPS6KA1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1More
Clotrimazolehsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Clotrimazolehsa04722Neurotrophin signaling pathway1.76E-0610Q05655, P31751, P04049, P49841, O43524, P48023, P52566, P51617, P10415, P0DP23PRKCD, AKT2, RAF1, GSK3B, FOXO3, FASLG, ARHGDIB, IRAK1, BCL2, CALM1More
Clotrimazolehsa04723Retrograde endocannabinoid signaling3.71E-024P62873, P61952, Q08828, O15239GNB1, GNG11, ADCY1, NDUFA1More
Clotrimazolehsa04724Glutamatergic synapse2.59E-067O15399, Q08828, P62873, P63218, P50151, P61952, P15104GRIN2D, ADCY1, GNB1, GNG5, GNG10, GNG11, GLULMore
Clotrimazolehsa04725Cholinergic synapse5.36E-0813Q08828, P51828, P22694, Q14643, P62873, P63218, P50151, P61952, P18848, Q13557, P42338, P31751, P10415ADCY1, ADCY7, PRKACB, ITPR1, GNB1, GNG5, GNG10, GNG11, ATF4, CAMK2D, PIK3CB, AKT2, BCL2More
Clotrimazolehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Clotrimazolehsa04727GABAergic synapse2.45E-099Q08828, P51828, P62873, P63218, P50151, P61952, P15104, P46459, Q15111ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, NSF, PLCL1More
Clotrimazolehsa04728Dopaminergic synapse1.26E-0918P14416, P62873, P63218, P50151, P61952, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP24, P0DP23, O15516, P48058DRD2, GNB1, GNG5, GNG10, GNG11, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM2, CALM1, CLOCK, GRIA4More
Clotrimazolehsa04730Long-term depression1.25E-042P08069, P04049IGF1R, RAF1More
Clotrimazolehsa04740Olfactory transduction4.52E-054P62873, Q13557, P0DP23, P0DP24GNB1, CAMK2D, CALM1, CALM2More
Clotrimazolehsa04742Taste transduction1.18E-032P30939, P17612HTR1F, PRKACAMore
Clotrimazolehsa04744Phototransduction1.45E-083P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Clotrimazolehsa04750Inflammatory mediator regulation of TRP channels1.96E-1214P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Clotrimazolehsa04810Regulation of actin cytoskeleton2.03E-0310P12814, Q13009, P04049, P42338, P11215, P16144, Q14344, Q9NRA1, P60709, P01042ACTN1, TIAM1, RAF1, PIK3CB, ITGAM, ITGB4, GNA13, PDGFC, ACTB, KNG1More
Clotrimazolehsa04910Insulin signaling pathway2.43E-056P0DP23, P22694, P06737, P04049, P31751, P49841CALM1, PRKACB, PYGL, RAF1, AKT2, GSK3BMore
Clotrimazolehsa04911Insulin secretion1.43E-086Q08828, P51828, P63092, Q99941, P18848, Q13557ADCY1, ADCY7, GNAS, CREBL1, ATF4, CAMK2DMore
Clotrimazolehsa04912GnRH signaling pathway3.92E-0611Q08828, P51828, P18848, Q16539, Q9Y6R4, Q14643, P0DP24, P0DP23, P22694, P04049, P45985ADCY1, ADCY7, ATF4, MAPK14, MAP3K4, ITPR1, CALM2, CALM1, PRKACB, RAF1, MAP2K4More
Clotrimazolehsa04913Ovarian steroidogenesis5.64E-054P42330, P22694, P06213, P08069AKR1C3, PRKACB, INSR, IGF1RMore
Clotrimazolehsa04914Progesterone-mediated oocyte maturation4.88E-1010P08069, Q17RY0, P42338, Q13370, Q9Y6D9, P30304, P08238, P51812, Q02750, P04049IGF1R, CPEB4, PIK3CB, PDE3B, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Clotrimazolehsa04915Estrogen signaling pathway8.54E-1012P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, P0DP24, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Clotrimazolehsa04916Melanogenesis7.31E-044P0DP23, Q08828, P51828, P04049CALM1, ADCY1, ADCY7, RAF1More
Clotrimazolehsa04917Prolactin signaling pathway3.49E-042P31751, P04049AKT2, RAF1More
Clotrimazolehsa04918Thyroid hormone synthesis2.73E-056Q08828, P51828, Q99941, P18848, P02768, P05543ADCY1, ADCY7, CREBL1, ATF4, ALB, SERPINA7More
Clotrimazolehsa04919Thyroid hormone signaling pathway3.02E-0611P49841, P19174, P04049, P42224, P22694, P60709, Q13547, O60244, Q9NVC6, Q9UM47, P01106GSK3B, PLCG1, RAF1, STAT1, PRKACB, ACTB, HDAC1, MED14, MED17, NOTCH3, MYCMore
Clotrimazolehsa04920Adipocytokine signaling pathway1.37E-048P25963, Q06124, P33121, Q9Y478, Q04759, Q96RR4, P31751, P01375NFKBIA, PTPN11, ACSL1, PRKAB1, PRKCQ, CAMKK2, AKT2, TNFMore
Clotrimazolehsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Clotrimazolehsa04922Glucagon signaling pathway4.34E-047P14618, P22694, P06737, Q12778, P31751, P0DP23, Q14643PKM2, PRKACB, PYGL, FOXO1, AKT2, CALM1, ITPR1More
Clotrimazolehsa04923Regulation of lipolysis in adipocytes4.29E-077Q08828, P51828, P07550, P06213, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, INSR, PIK3CB, IRS2, AKT2More
Clotrimazolehsa04924Renin secretion1.12E-094P22694, P07550, Q14643, P0DP23PRKACB, ADRB2, ITPR1, CALM1More
Clotrimazolehsa04925Aldosterone synthesis and secretion9.47E-109Q99941, P18848, Q08828, P51828, P0DP24, P0DP23, P63092, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM2, CALM1, GNAS, CAMK2D, ATP2B4More
Clotrimazolehsa04926Relaxin signaling pathway5.04E-1017P31751, P25963, P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P22694, P49767, P14780, Q08828, P51828, P04049, P30679, P49407AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, PRKACB, VEGFC, MMP9, ADCY1, ADCY7, RAF1, GNA15, ARRB1More
Clotrimazolehsa04927Cortisol synthesis and secretion4.95E-097Q14643, Q99941, P18848, Q08828, P51828, P63092, P22694ITPR1, CREBL1, ATF4, ADCY1, ADCY7, GNAS, PRKACBMore
Clotrimazolehsa04928Parathyroid hormone synthesis, secretion and action3.62E-059Q14643, P63092, P22694, P23771, P04049, P61586, Q99941, P18848, P10415ITPR1, GNAS, PRKACB, GATA3, RAF1, RHOA, CREBL1, ATF4, BCL2More
Clotrimazolehsa04929GnRH secretion6.93E-064P42338, P31751, P49407, P04049PIK3CB, AKT2, ARRB1, RAF1More
Clotrimazolehsa04930Type II diabetes mellitus6.29E-053P06213, Q05655, Q02156INSR, PRKCD, PRKCEMore
Clotrimazolehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Clotrimazolehsa04932Non-alcoholic fatty liver disease1.87E-1316P31751, P01375, P49841, Q14790, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, Q16718, O95298, P19404, O14521AKT2, TNF, GSK3B, CASP8, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHDMore
Clotrimazolehsa04933AGE-RAGE signaling pathway in diabetic complications2.11E-036P84022, Q13485, P10415, P42338, P49767, P19174SMAD3, SMAD4, BCL2, PIK3CB, VEGFC, PLCG1More
Clotrimazolehsa04934Cushing syndrome4.47E-1010Q14643, Q99941, P18848, Q08828, P51828, P63092, P22694, O15169, Q13557, P04628ITPR1, CREBL1, ATF4, ADCY1, ADCY7, GNAS, PRKACB, AXIN1, CAMK2D, WNT1More
Clotrimazolehsa04935Growth hormone synthesis, secretion and action5.87E-046Q08828, P51828, P04049, P18848, P31751, P45985ADCY1, ADCY7, RAF1, ATF4, AKT2, MAP2K4More
Clotrimazolehsa04940Type I diabetes mellitus7.38E-044P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Clotrimazolehsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Clotrimazolehsa04962Vasopressin-regulated water reabsorption7.22E-032P52566, P62491ARHGDIB, RAB11AMore
Clotrimazolehsa04964Proximal tubule bicarbonate reclamation4.48E-021P00918CA2More
Clotrimazolehsa04966Collecting duct acid secretion4.48E-021P00918CA2More
Clotrimazolehsa04970Salivary secretion1.81E-1211P07550, Q08828, P51828, P22694, Q14643, P23634, P17252, P0DP24, P0DP23, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B4, PRKCA, CALM2, CALM1, GUCY1B3, CAMPMore
Clotrimazolehsa04971Gastric acid secretion3.36E-076Q08828, P51828, P15311, P0DP24, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM2, CALM1, CAMK2DMore
Clotrimazolehsa04972Pancreatic secretion1.31E-022Q08828, P62491ADCY1, RAB11AMore
Clotrimazolehsa04973Carbohydrate digestion and absorption4.61E-033O43451, P42338, P31751MGAM, PIK3CB, AKT2More
Clotrimazolehsa04974Protein digestion and absorption1.22E-032Q7Z2H8, P02452SLC36A1, COL1A1More
Clotrimazolehsa04975Fat digestion and absorption1.68E-031O14494PLPP1More
Clotrimazolehsa04976Bile secretion8.33E-076O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Clotrimazolehsa04979Cholesterol metabolism1.37E-023P38571, P61916, P45880LIPA, NPC2, VDAC2More
Clotrimazolehsa05010Alzheimer disease2.47E-1022P49768, Q92542, O15239, O95298, P19404, P05496, P13073, P12074, Q00535, O75460, P0DP23, P01584, Q12933, P18848, O15169, P67870, P31751, P05141, P12236, P28070, P43686, P62195PSEN1, NCSTN, NDUFA1, NDUFC2, NDUFV2, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, CALM1, IL1B, TRAF2, ATF4, AXIN1, CSNK2B, AKT2, SLC25A5, SLC25A6, PSMB4, PSMC4, PSMC5More
Clotrimazolehsa05012Parkinson disease1.64E-0621O15239, O95298, P13073, P12074, P05496, P05141, P12236, P21796, P60604, P63092, O75460, P18848, P28070, P43686, P62195, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, SLC25A5, SLC25A6, VDAC1, UBE2G2, GNAS, ERN1, ATF4, PSMB4, PSMC4, PSMC5, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3More
Clotrimazolehsa05014Amyotrophic lateral sclerosis8.33E-0422P01375, P20333, O15239, Q16718, P19404, O14521, P12074, P36542, P05496, O75460, P18848, P28070, P43686, P62195, Q8TEV9, P51991, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, TNFRSF1B, NDUFA1, NDUFA5, NDUFV2, SDHD, COX6A1, ATP5C1, ATP5G1, ERN1, ATF4, PSMB4, PSMC4, PSMC5, SMCR8, HNRPA3, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Clotrimazolehsa05016Huntington disease8.53E-0915O95298, P19404, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, P05141, P45880, Q9NYC9, O75460, P28070, O00232NDUFC2, NDUFV2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, VDAC2, DNAH9, ERN1, PSMB4, PSMD12More
Clotrimazolehsa05017Spinocerebellar ataxia1.88E-049Q92915, O75460, Q8TB72, O15399, P42338, P31751, P28070, P05141, P21796FGF14, ERN1, PUM2, GRIN2D, PIK3CB, AKT2, PSMB4, SLC25A5, VDAC1More
Clotrimazolehsa05020Prion disease3.17E-0821P01584, P46531, P0DMV8, P11142, O15239, Q16718, O95298, O14521, P05496, P13073, P12074, P18848, P05141, P12236, P28070, P43686, P62195, P49841, P67870, Q99941, Q16539IL1B, NOTCH1, HSPA1A, HSPA8, NDUFA1, NDUFA5, NDUFC2, SDHD, ATP5G1, COX4I1, COX6A1, ATF4, SLC25A5, SLC25A6, PSMB4, PSMC4, PSMC5, GSK3B, CSNK2B, CREBL1, MAPK14More
Clotrimazolehsa05022Pathways of neurodegeneration - multiple diseases3.51E-1135P49841, P67870, O15239, Q16718, O95298, P19404, O14521, P13073, P12074, P05496, Q06055, Q8TEV9, O75460, P18848, Q12933, Q13561, P05141, P12236, P45880, P20333, Q16539, Q15078, Q00535, O15169, P01584, P49768, Q08752, O15020, P0DP24, P0DP23, Q13557, P62987, P28070, P43686, P62195GSK3B, CSNK2B, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, COX4I1, COX6A1, ATP5G1, ATP5G2, SMCR8, ERN1, ATF4, TRAF2, DCTN2, SLC25A5, SLC25A6, VDAC2, TNFRSF1B, MAPK14, CDK5R1, CDK5, AXIN1, IL1B, PSEN1, PPID, SPTBN2, CALM2, CALM1, CAMK2D, UBA52, PSMB4, PSMC4, PSMC5More
Clotrimazolehsa05030Cocaine addiction4.69E-044P63092, Q00535, Q99941, P18848GNAS, CDK5, CREBL1, ATF4More
Clotrimazolehsa05031Amphetamine addiction1.03E-078P0DP24, P0DP23, Q13557, P22694, P63092, Q99941, P18848, Q13547CALM2, CALM1, CAMK2D, PRKACB, GNAS, CREBL1, ATF4, HDAC1More
Clotrimazolehsa05032Morphine addiction4.50E-047P62873, P63218, P50151, Q13370, P78334, P32298, P43250GNB1, GNG5, GNG10, PDE3B, GABRE, GRK4, GRK6More
Clotrimazolehsa05033Nicotine addiction4.01E-021P78334GABREMore
Clotrimazolehsa05034Alcoholism3.38E-1020Q99941, P18848, Q13547, P0DP23, P0DP24, Q96RR4, P62873, P63218, P50151, P61952, P04049, P0C0S5, Q93077, P58876, P62807, Q93079, Q16778, O60814, P84243, P68431CREBL1, ATF4, HDAC1, CALM1, CALM2, CAMKK2, GNB1, GNG5, GNG10, GNG11, RAF1, H2AFZ, HIST1H2AC, H2BC5, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3F3A, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Clotrimazolehsa05100Bacterial invasion of epithelial cells2.23E-044Q14141, Q05397, Q92529, Q96JJ3SEPT6, PTK2, SHC3, ELMO2More
Clotrimazolehsa05110Vibrio cholerae infection2.11E-032Q99437, P17612ATP6V0B, PRKACAMore
Clotrimazolehsa05120Epithelial cell signaling in Helicobacter pylori infection2.58E-1311Q16539, Q99437, Q13153, P09341, P19875, P10145, P19174, P25024, P25025, P41240, P07948MAPK14, ATP6V0B, PAK1, CXCL1, CXCL2, IL8, PLCG1, CXCR1, CXCR2, CSK, LYNMore
Clotrimazolehsa05130Pathogenic Escherichia coli infection1.02E-0413P16333, Q92974, Q13509, P60709, P63261, P25963, P04406, P29350, Q06124, Q15438, P35579, P55061, O95487NCK1, ARHGEF2, TUBB3, ACTB, ACTG1, NFKBIA, GAPDH, PTPN6, PTPN11, PSCD1, MYH9, TEGT, SEC24BMore
Clotrimazolehsa05131Shigellosis1.11E-0521P01375, P25963, Q12933, O00463, Q13546, Q05655, Q02156, Q04759, Q9UDY8, Q9NQL2, Q9H1Y0, P0CG47, Q14141, Q96JJ3, Q05397, Q14643, Q12778, Q13315, P10415, Q96A32, P07737TNF, NFKBIA, TRAF2, TRAF5, RIPK1, PRKCD, PRKCE, PRKCQ, MALT1, RRAGD, ATG5, UBB, SEPT6, ELMO2, PTK2, ITPR1, FOXO1, ATM, BCL2, MYLPF, PFN1More
Clotrimazolehsa05132Salmonella infection9.61E-1124P51617, P25963, P01375, P08238, P04049, Q9UJU2, P01106, P84095, P60709, P42338, Q13546, Q13489, P10415, P04406, O75369, P07737, Q96A32, O60603, Q9BQS8, Q13561, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, RAF1, LEF1, MYC, RHOG, ACTB, PIK3CB, RIPK1, BIRC3, BCL2, GAPDH, FLNB, PFN1, MYLPF, TLR2, FYCO1, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Clotrimazolehsa05133Pertussis1.43E-053P05107, P10145, P0C0L4ITGB2, IL8, C4AMore
Clotrimazolehsa05134Legionellosis1.05E-099P01584, P25963, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Clotrimazolehsa05135Yersinia infection2.90E-0614P60709, Q05397, P51812, P13612, P06239, P19174, Q16539, Q02750, P01375, P42338, P49841, Q96JJ3, P01730, P01732ACTB, PTK2, RPS6KA3, ITGA4, LCK, PLCG1, MAPK14, MAP2K1, TNF, PIK3CB, GSK3B, ELMO2, CD4, CD8AMore
Clotrimazolehsa05140Leishmaniasis7.13E-1016P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Clotrimazolehsa05142Chagas disease2.70E-022P48023, Q14790FASLG, CASP8More
Clotrimazolehsa05143African trypanosomiasis1.54E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Clotrimazolehsa05144Malaria3.00E-1010P60033, P69905, P68871, O60603, P01375, P05107, P35443, P01584, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, ITGB2, THBS4, IL1B, IL8, KLRK1More
Clotrimazolehsa05145Toxoplasmosis4.06E-037P51617, P25963, P01375, P10415, Q13489, P13765, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, HLA-DOB, TLR2More
Clotrimazolehsa05146Amoebiasis2.30E-2014P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Clotrimazolehsa05150Staphylococcus aureus infection1.11E-0915P09871, P0C0L4, P21730, P21462, O75015, P31995, P13765, P13646, Q14532, P05107, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, FCGR2C, HLA-DOB, KRT13, KRT32, ITGB2, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Clotrimazolehsa05152Tuberculosis9.30E-0614P04049, Q13488, Q15075, P0DP23, P48382, O60603, P01375, P31751, P10415, P13765, Q13651, P49913, Q9UDY8, P51617RAF1, TCIRG1, EEA1, CALM1, RFX5, TLR2, TNF, AKT2, BCL2, HLA-DOB, IL10RA, CAMP, MALT1, IRAK1More
Clotrimazolehsa05160Hepatitis C2.07E-0510Q13546, P01568, P60033, O00501, P29728, P04049, P49841, P01375, P48023, P01106RIPK1, IFNA21, CD81, CLDN5, OAS2, RAF1, GSK3B, TNF, FASLG, MYCMore
Clotrimazolehsa05161Hepatitis B2.46E-0514P17252, P04049, P14780, Q99941, P18848, P25963, Q13485, P01375, P10415, P27348, P84022, P51617, O60603, Q14765PRKCA, RAF1, MMP9, CREBL1, ATF4, NFKBIA, SMAD4, TNF, BCL2, YWHAQ, SMAD3, IRAK1, TLR2, STAT4More
Clotrimazolehsa05162Measles3.90E-0513P01568, P25963, P23458, P42224, P14784, P07766, P42338, P31751, P0DMV8, P11142, P01584, P67870, Q9NP90IFNA21, NFKBIA, JAK1, STAT1, IL2RB, CD3E, PIK3CB, AKT2, HSPA1A, HSPA8, IL1B, CSNK2B, RAB9BMore
Clotrimazolehsa05163Human cytomegalovirus infection6.11E-1431P31751, P42338, P04049, P01375, P25963, P62873, P63218, P50151, P61952, Q14643, P0DP23, P0DP24, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P01106, P14778, P01584, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P30101, P61769, P01568AKT2, PIK3CB, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, GNG11, ITPR1, CALM1, CALM2, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, MYC, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, PDIA3, B2M, IFNA21More
Clotrimazolehsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Clotrimazolehsa05165Human papillomavirus infection2.80E-0410P02452, P24821, Q16363, P30281, Q9UM47, P01568, P01889, P10321, Q99437, P04628COL1A1, TNC, LAMA4, CCND3, NOTCH3, IFNA21, HLA-B, HLA-C, ATP6V0B, WNT1More
Clotrimazolehsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Clotrimazolehsa05167Kaposi sarcoma-associated herpesvirus infection8.73E-0917P01568, P31751, P42224, P25963, P42338, P62873, P62879, P63218, P50151, P19174, P16298, P04049, Q02750, P07948, P01106, P0DP23, P0CG47IFNA21, AKT2, STAT1, NFKBIA, PIK3CB, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, RAF1, MAP2K1, LYN, MYC, CALM1, UBBMore
Clotrimazolehsa05168Herpes simplex virus 1 infection7.34E-0423O00463, O60603, P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q16629, P30101, P42338, Q9Y2A4, Q13398, P51522, Q9NR11, P17097, P17038, Q03923, P52738, O75820, Q9UDV6, P10415TRAF5, TLR2, NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, SFRS7, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF302, ZNF7, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212, BCL2More
Clotrimazolehsa05169Epstein-Barr virus infection1.16E-0820P13765, P01106, Q13547, O00463, P25963, P10415, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, P01375, O60603, P29728, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, NFKBIA, BCL2, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, TNF, TLR2, OAS2, CD3E, CD3G, CD247More
Clotrimazolehsa05170Human immunodeficiency virus 1 infection5.37E-1229P31751, P42338, P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, P01375, Q05397, P17252, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P07766, P10415, Q13619, Q93034, Q9Y6Q5, P20333AKT2, PIK3CB, RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, CD3E, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Clotrimazolehsa05171Coronavirus disease - COVID-193.96E-0917P23396, P62753, P25398, P42677, P36578, Q02878, P62917, P32969, P27635, P26373, Q07020, P46776, P62899, P62910, P18077, P61927, P05386RPS3, RPS6, RPS12, RPS27, RPL4, RPL6, RPL8, RPL9, RPL10, RPL13, RPL18, RPL27A, RPL31, RPL32, RPL35A, RPL37, RPLP1More
Clotrimazolehsa05200Pathways in cancer1.88E-0935Q13751, P42338, P08238, P42224, P25963, P19174, P01106, Q9UJU2, P43246, P84022, Q13485, P20585, P52701, Q13547, P14923, P30279, P30281, P10415, Q13077, P49767, P14921, P31751, P43657, P62873, P63218, P50151, Q14344, Q7LDG7, Q9UM47, P78417, O75293, P0DP23, P01568, P14784, P01042LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, LEF1, MSH2, SMAD3, SMAD4, MSH3, MSH6, HDAC1, JUP, CCND2, CCND3, BCL2, TRAF1, VEGFC, ETS1, AKT2, P2RY5, GNB1, GNG5, GNG10, GNA13, RASGRP2, NOTCH3, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, KNG1More
Clotrimazolehsa05202Transcriptional misregulation in cancer9.02E-1425Q12778, Q15532, Q13315, P41732, P17844, P14780, P27930, P14923, Q15744, Q16548, P11215, Q13489, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, DDX5, MMP9, IL1R2, JUP, CEBPE, BCL2A1, ITGAM, BIRC3, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Clotrimazolehsa05203Viral carcinogenesis3.20E-1024Q12933, Q99941, P18848, P42338, P06746, P07948, P30281, P27348, P29083, Q13547, Q15283, P61586, P06396, P12814, P25963, P01889, P10321, P61978, P06493, P58876, P62807, Q93079, Q16778, O60814TRAF2, CREBL1, ATF4, PIK3CB, POLB, LYN, CCND3, YWHAQ, GTF2E1, HDAC1, RASA2, RHOA, GSN, ACTN1, NFKBIA, HLA-B, HLA-C, HNRPK, CDK1, H2BC5, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12More
Clotrimazolehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Clotrimazolehsa05205Proteoglycans in cancer9.53E-0615Q13009, Q12955, O75369, P60709, P04049, P14780, P01106, P01375, P08069, P23588, P19174, Q13635, P22694, P29350, P08962TIAM1, ANK3, FLNB, ACTB, RAF1, MMP9, MYC, TNF, IGF1R, EIF4B, PLCG1, PTCH1, PRKACB, PTPN6, CD63More
Clotrimazolehsa05206MicroRNAs in cancer4.34E-0414P30304, P09493, P21860, P01106, P42338, P61978, P46531, Q13547, P63279, P22105, P61586, P20827, P19174, P04049CDC25A, TPM1, ERBB3, MYC, PIK3CB, HNRPK, NOTCH1, HDAC1, UBE2I, TNXB, RHOA, EFNA1, PLCG1, RAF1More
Clotrimazolehsa05210Colorectal cancer8.05E-0611Q9UKG1, P84022, Q13485, P43246, P04049, P01106, P10415, P52701, P20585, P37173, O75293APPL1, SMAD3, SMAD4, MSH2, RAF1, MYC, BCL2, MSH6, MSH3, TGFBR2, GADD45BMore
Clotrimazolehsa05211Renal cell carcinoma1.84E-055Q06124, Q99814, Q13153, P31751, P04049PTPN11, EPAS1, PAK1, AKT2, RAF1More
Clotrimazolehsa05212Pancreatic cancer1.45E-058P42338, P31751, P04049, Q15311, P23458, P84022, Q13485, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, SMAD3, SMAD4, GADD45BMore
Clotrimazolehsa05213Endometrial cancer4.41E-044O15169, P31751, Q02750, P04049AXIN1, AKT2, MAP2K1, RAF1More
Clotrimazolehsa05214Glioma6.04E-077P08069, P0DP23, P04049, P42338, P31751, P19174, O75293IGF1R, CALM1, RAF1, PIK3CB, AKT2, PLCG1, GADD45BMore
Clotrimazolehsa05215Prostate cancer2.34E-045P10415, Q12778, P08069, Q9NRA1, P04049BCL2, FOXO1, IGF1R, PDGFC, RAF1More
Clotrimazolehsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Clotrimazolehsa05217Basal cell carcinoma7.91E-035Q13635, P04628, P49841, Q9UJU2, P24522PTCH1, WNT1, GSK3B, LEF1, GADD45AMore
Clotrimazolehsa05218Melanoma3.78E-056P08069, Q9NRA1, P31751, P42338, P04049, O75293IGF1R, PDGFC, AKT2, PIK3CB, RAF1, GADD45BMore
Clotrimazolehsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Clotrimazolehsa05220Chronic myeloid leukemia1.24E-069Q13547, P01106, Q13485, P25963, P84022, P31751, P42338, P04049, O75293HDAC1, MYC, SMAD4, NFKBIA, SMAD3, AKT2, PIK3CB, RAF1, GADD45BMore
Clotrimazolehsa05221Acute myeloid leukemia8.73E-045P31751, P42338, P04049, Q15744, P11215AKT2, PIK3CB, RAF1, CEBPE, ITGAMMore
Clotrimazolehsa05222Small cell lung cancer3.73E-047P31751, Q13489, P10415, P25963, Q13077, O00463, P24522AKT2, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45AMore
Clotrimazolehsa05223Non-small cell lung cancer3.89E-055P31751, P10826, P04049, Q9HC35, O75293AKT2, RARB, RAF1, EML4, GADD45BMore
Clotrimazolehsa05224Breast cancer2.75E-036P04049, P08069, P49841, Q92837, P04637, P24522RAF1, IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Clotrimazolehsa05225Hepatocellular carcinoma1.65E-042P04049, P08069RAF1, IGF1RMore
Clotrimazolehsa05226Gastric cancer2.61E-057P04049, Q02750, P31751, O15169, P84022, Q13485, P10415RAF1, MAP2K1, AKT2, AXIN1, SMAD3, SMAD4, BCL2More
Clotrimazolehsa05230Central carbon metabolism in cancer1.12E-032P04049, P31751RAF1, AKT2More
Clotrimazolehsa05231Choline metabolism in cancer2.98E-0811P04049, P31751, P42338, Q9NRA1, Q9Y259, P19174, P23743, P49619, Q16760, O14986, O14494RAF1, AKT2, PIK3CB, PDGFC, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PLPP1More
Clotrimazolehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.12E-2118P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P04049, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, RAF1, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Clotrimazolehsa05310Asthma1.58E-093P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Clotrimazolehsa05321Inflammatory bowel disease3.04E-208O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Clotrimazolehsa05322Systemic lupus erythematosus2.07E-1018P08637, O75015, P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P14678, P12814, P05455FCGR3A, FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SNRPB, ACTN1, SSBMore
Clotrimazolehsa05323Rheumatoid arthritis9.02E-067P01375, Q06643, P13765, P10747, P09341, P19875, O60603TNF, LTB, HLA-DOB, CD28, CXCL1, CXCL2, TLR2More
Clotrimazolehsa05330Allograft rejection2.02E-034P13765, P48023, P10747, P01375HLA-DOB, FASLG, CD28, TNFMore
Clotrimazolehsa05332Graft-versus-host disease1.44E-176P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Clotrimazolehsa05340Primary immunodeficiency2.20E-086P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Clotrimazolehsa05410Hypertrophic cardiomyopathy3.63E-022P26012, P09493ITGB8, TPM1More
Clotrimazolehsa05412Arrhythmogenic right ventricular cardiomyopathy4.48E-021P54284CACNB3More
Clotrimazolehsa05414Dilated cardiomyopathy3.78E-034P54284, P26012, P09493, P26678CACNB3, ITGB8, TPM1, PLNMore
Clotrimazolehsa05415Diabetic cardiomyopathy6.95E-0614P30405, P05141, P12236, Q15080, O15239, Q16718, O14521, P05496, Q16539, P49841, Q13557, P14780, P37173, P26678PPIF, SLC25A5, SLC25A6, NCF4, NDUFA1, NDUFA5, SDHD, ATP5G1, MAPK14, GSK3B, CAMK2D, MMP9, TGFBR2, PLNMore
Clotrimazolehsa05418Fluid shear stress and atherosclerosis2.26E-0610Q16539, P31751, Q14145, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23MAPK14, AKT2, KEAP1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1More

Community members of Clotrimazole (SDC: 13.01)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
O75469NR1I2Nuclear receptor subfamily 1 group I member 2Reported10.03150.949301.9143
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P22001KCNA3Potassium voltageNonegated channel subfamily A member 3Predicted10.13960.505501.0809
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P40925MDH1Malate dehydrogenase, cytoplasmicPredicted00.35660.27460.24260.97
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
Q13133NR1H3Oxysterols receptor LXRNonealphaPredicted00.01620.4390.20861.0947
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
O00767SCDStearoylNoneCoA desaturasePredicted10.16860.1870.19970.6581
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
P21453S1PR1Sphingosine 1Nonephosphate receptor 1Predicted10.14340.38470.2211.0621
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
Q06609RAD51DNA repair protein RAD51 homolog 1Predicted00.10220.09540.27250.5144
P40926MDH2Malate dehydrogenase, mitochondrialPredicted00.47210.16110.24740.8055
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
Q06124PTPN11TyrosineNoneprotein phosphatase nonNonereceptor type 11Predicted10.15130.45660.6131.6017
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P30530AXLTyrosineNoneprotein kinase receptor UFOPredicted10.37970.53650.16371.4264
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
Q2M2I8AAK1AP2Noneassociated protein kinase 1Predicted10.37690.328800.846
Q9UEE5STK17ASerine/threonineNoneprotein kinase 17APredicted00.35040.337600.8504
Q15418RPS6KA1Ribosomal protein S6 kinase alphaNone1Predicted10.8320.32450.41461.4796
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
Q9Y6R4MAP3K4MitogenNoneactivated protein kinase kinase kinase 4Predicted00.35280.24520.1730.8399
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P24723PRKCHProtein kinase C eta typePredicted00.19550.32940.20480.9614
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
Q13153PAK1Serine/threonineNoneprotein kinase PAK 1Predicted10.46470.34710.78191.7084
P22694PRKACBcAMPNonedependent protein kinase catalytic subunit betaPredicted00.37370.298411.7836
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
P45985MAP2K4Dual specificity mitogenNoneactivated protein kinase kinase 4Predicted00.42480.24730.74031.4474
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
Q9Y6E0STK24Serine/threonineNoneprotein kinase 24Predicted00.54580.245200.7634
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
O43318MAP3K7MitogenNoneactivated protein kinase kinase kinase 7Predicted00.00590.364911.7327
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
Q9P289STK26Serine/threonineNoneprotein kinase 26Predicted10.02850.262800.5399
Q9NQU5PAK6Serine/threonineNoneprotein kinase PAK 6Predicted00.4090.26690.50031.2386
Q8NI60CABC1Atypical kinase COQ8A, mitochondrialPredicted00.62760.245200.8043
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
Q15831STK11Serine/threonineNoneprotein kinase STK11Predicted00.15110.24410.45491.0186
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
Q07912TNK2Activated CDC42 kinase 1Predicted00.0090.347200.6988
P32298GRK4G proteinNonecoupled receptor kinase 4Predicted00.03520.23860.29480.7896
Q8IVH8MAP4K3MitogenNoneactivated protein kinase kinase kinase kinase 3Predicted00.38330.26730.14870.875
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
Q13523PRPF4BSerine/threonineNoneprotein kinase PRP4 homologPredicted00.13760.245200.5593
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
P41240CSKTyrosineNoneprotein kinase CSKPredicted00.69860.36260.10231.1768
Q8IVW4CDKL3CyclinNonedependent kinaseNonelike 3Predicted00.41490.241600.6906
Q13873BMPR2Bone morphogenetic protein receptor typeNone2Predicted10.34760.24520.35481.019
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
O75460ERN1Serine/threonineNoneprotein kinase/endoribonuclease IRE1Predicted10.68060.29440.5571.4862
P51617IRAK1InterleukinNone1 receptorNoneassociated kinase 1Predicted00.02380.30.94441.5563
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
Q16566CAMK4Calcium/calmodulinNonedependent protein kinase type IVPredicted00.07180.24410.61761.1417
P21860ERBB3Receptor tyrosineNoneprotein kinase erbBNone3Predicted00.1260.27290.47881.0876
P07332FESTyrosineNoneprotein kinase Fes/FpsPredicted00.27220.26280.15130.8131
P07948LYNTyrosineNoneprotein kinase LynPredicted00.0910.53190.6061.7154
Q99759MAP3K3MitogenNoneactivated protein kinase kinase kinase 3Predicted00.35450.24520.43781.1055
P51955NEK2Serine/threonineNoneprotein kinase Nek2Predicted00.65990.369201.0684
O95835LATS1Serine/threonineNoneprotein kinase LATS1Predicted00.43320.24520.02170.7288
O43283MAP3K13MitogenNoneactivated protein kinase kinase kinase 13Predicted00.45650.24520.14870.8674
P51817PRKXcAMPNonedependent protein kinase catalytic subunit PRKXPredicted00.40630.276500.7562
O95747OXSR1Serine/threonineNoneprotein kinase OSR1Predicted00.18390.245200.5825
P09769FGRTyrosineNoneprotein kinase FgrPredicted00.06220.32440.2250.9049
O14976GAKCyclinNoneGNoneassociated kinasePredicted10.57280.256200.7989
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
Q02156PRKCEProtein kinase C epsilon typePredicted00.11750.52870.53771.6539
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q9H422HIPK3HomeodomainNoneinteracting protein kinase 3Predicted00.3650.25080.2180.902
O94806PRKD3Serine/threonineNoneprotein kinase D3Predicted00.23120.24340.16920.7715
Q00536PCTK1CyclinNonedependent kinase 16Predicted00.27140.25600.6478
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
Q16513PKN2Serine/threonineNoneprotein kinase N2Predicted00.04210.27780.33910.9157
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
Q9UEW8STK39STE20/SPS1Nonerelated prolineNonealanineNonerich protein kinasePredicted00.25730.245200.6191
Q96BR1SGK3Serine/threonineNoneprotein kinase Sgk3Predicted00.0260.26840.31140.8612
Q9H2K8TAOK3Serine/threonineNoneprotein kinase TAO3Predicted00.06460.24520.14870.6715
P31751AKT2RACNonebeta serine/threonineNoneprotein kinasePredicted00.46620.485612.2044
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P01106MYCMyc protoNoneoncogene proteinPredicted00.12370.02911.1198
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P17707AMD1SNoneadenosylmethionine decarboxylase proenzymePredicted00.80270.05050.16450.6667
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
O15151MDM4Protein Mdm4Predicted00.10140.08980.24890.4791
O15164TRIM24Transcription intermediary factor 1NonealphaPredicted00.28070.105500.3514
P16083NQO2Ribosyldihydronicotinamide dehydrogenase [quinone]Predicted00.29580.313400.7747
P20292ALOX5APArachidonate 5NonelipoxygenaseNoneactivating proteinPredicted00.13030.24180.09070.6395
P49019HCAR3Hydroxycarboxylic acid receptor 3Predicted00.0130.02180.01130.0614
P10826RARBRetinoic acid receptor betaPredicted00.00940.34660.30050.9983
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)