PharmaCoNets

PharmaCoNets of Clopidogrel (S_PCN: 57.13 )

Clopidogrel regulated-network (S_DN: 11.38)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Clopidogrel

hsa00190

Oxidative phosphorylation

2.53E-05

Q16718, Q13488, P36542, O14521

NDUFA5, TCIRG1, ATP5C1, SDHD

Clopidogrel

hsa00230

Purine metabolism

2.05E-03

Q7LG56, P31350, P21589

RRM2B, RRM2, NT5E

Clopidogrel

hsa00240

Pyrimidine metabolism

1.33E-09

Q7LG56, P31350, P21589, P04183, P04818

RRM2B, RRM2, NT5E, TK1, TYMS

Clopidogrel

hsa00480

Glutathione metabolism

3.85E-02

Q7LG56, P31350

RRM2B, RRM2

Clopidogrel

hsa00590

Arachidonic acid metabolism

3.85E-02

P11712, P09960

CYP2C9, LTA4H

Clopidogrel

hsa00591

Linoleic acid metabolism

4.07E-02

P11712

CYP2C9

Clopidogrel

hsa00670

One carbon pool by folate

3.15E-02

O95954, Q99707

FTCD, MTR

Clopidogrel

hsa00770

Pantothenate and CoA biosynthesis

1.15E-02

O95498, Q9NRN7

VNN2, AASDHPPT

Clopidogrel

hsa00860

Porphyrin and chlorophyll metabolism

3.15E-02

P36551, P30043

CPOX, BLVRB

Clopidogrel

hsa00980

Metabolism of xenobiotics by cytochrome P450

9.14E-03

P78417, P11712

GSTO1, CYP2C9

Clopidogrel

hsa00982

Drug metabolism - cytochrome P450

9.14E-03

P11712, P78417

CYP2C9, GSTO1

Clopidogrel

hsa00983

Drug metabolism - other enzymes

6.98E-05

P04183, Q7LG56, P31350, P05164

TK1, RRM2B, RRM2, MPO

Clopidogrel

hsa01523

Antifolate resistance

6.06E-03

Q92820, P04818

GGH, TYMS

Clopidogrel

hsa01524

Platinum drug resistance

1.79E-02

O15392, P11388

BIRC5, TOP2A

Clopidogrel

hsa02010

ABC transporters

2.29E-02

P45844, P08183

ABCG1, ABCB1

Clopidogrel

hsa03008

Ribosome biogenesis in eukaryotes

8.16E-03

Q9NYH9, P78345, Q9GZY0

UTP6, RPP38, NXF2; NXF2B

Clopidogrel

hsa03013

RNA transport

4.22E-08

O14980, Q09161, O14893, P61326, Q9H307, Q7Z3B4, P35658, P47813, Q14152, O75822, Q14240, Q9BZI7, Q06787, P51114

XPO1, NCBP1, GEMIN2, MAGOH, PNN, NUP54, NUP214, EIF1AX, EIF3A, EIF3J, EIF4A2, UPF3B, FMR1, FXR1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	O14980	XPO1	Exportin-1	0.799
Q9UBU7	DBF4	Protein DBF4 homolog A	O14980	XPO1	Exportin-1	0.943
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q09161	NCBP1	Nuclear cap-binding protein subunit 1	0.771
Q9UBU7	DBF4	Protein DBF4 homolog A	Q09161	NCBP1	Nuclear cap-binding protein subunit 1	0.742
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	O14893	GEMIN2	Gem-associated protein 2	0.72
Q9UBU7	DBF4	Protein DBF4 homolog A	P61326	MAGOH	Protein mago nashi homolog	0.737
Q9UBU7	DBF4	Protein DBF4 homolog A	Q9H307	PNN	Pinin	0.722
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q7Z3B4	NUP54	Nucleoporin p54	0.883
Q9UBU7	DBF4	Protein DBF4 homolog A	Q7Z3B4	NUP54	Nucleoporin p54	0.787
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	P35658	NUP214	Nuclear pore complex protein Nup214	-0.708
Q9UBU7	DBF4	Protein DBF4 homolog A	P35658	NUP214	Nuclear pore complex protein Nup214	-0.781
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	P47813	EIF1AX	Eukaryotic translation initiation factor 1A, X-chromosomal	0.844
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q14152	EIF3A	Eukaryotic translation initiation factor 3 subunit A	0.869
Q9UBU7	DBF4	Protein DBF4 homolog A	Q14152	EIF3A	Eukaryotic translation initiation factor 3 subunit A	0.902
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	O75822	EIF3J	Eukaryotic translation initiation factor 3 subunit J	0.77
Q9UBU7	DBF4	Protein DBF4 homolog A	O75822	EIF3J	Eukaryotic translation initiation factor 3 subunit J	0.83
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q14240	EIF4A2	Eukaryotic initiation factor 4A-II	0.849
Q9UBU7	DBF4	Protein DBF4 homolog A	Q14240	EIF4A2	Eukaryotic initiation factor 4A-II	0.867
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q9BZI7	UPF3B	Regulator of nonsense transcripts 3B	0.764
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	Q06787	FMR1	Synaptic functional regulator FMR1	0.863
Q9UBU7	DBF4	Protein DBF4 homolog A	Q06787	FMR1	Synaptic functional regulator FMR1	0.772
Q96EB6	SIRT1	NAD-dependent protein deacetylase sirtuin-1	P51114	FXR1	Fragile X mental retardation syndrome-related protein 1	0.798
Q9UBU7	DBF4	Protein DBF4 homolog A	P51114	FXR1	Fragile X mental retardation syndrome-related protein 1	0.854

Clopidogrel

hsa03015

mRNA surveillance pathway

3.37E-02

O43148, Q9GZY0, P52298

RNMT, NXF2; NXF2B, NCBP2

Clopidogrel

hsa03018

RNA degradation

5.00E-02

Q9NQT4

EXOSC5

Clopidogrel

hsa03020

RNA polymerase

9.86E-07

Q9GZM3, P52435

POLR2J2, POLR2J

Clopidogrel

hsa03022

Basal transcription factors

2.97E-03

P20226, O00268, Q15544

TBP, TAF4, TAF11

Clopidogrel

hsa04061

Viral protein interaction with cytokine and cytokine receptor

4.48E-02

P09341, P19875, P25024, P25025, P14784

CXCL1, CXCL2, CXCR1, CXCR2, IL2RB

Clopidogrel

hsa04062

Chemokine signaling pathway

1.83E-02

P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151

CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10

Clopidogrel

hsa04064

NF-kappa B signaling pathway

7.27E-04

Q13489, Q13546, P14778, P19174, Q04759, Q9UDY8, P06239, P09341, P19875, Q06643, Q9UNE0

BIRC3, RIPK1, IL1R1, PLCG1, PRKCQ, MALT1, LCK, CXCL1, CXCL2, LTB, EDAR

Clopidogrel

hsa04072

Phospholipase D signaling pathway

4.48E-02

P42338, P43657, P25024, P25025, P19174

PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1

Clopidogrel

hsa04110

Cell cycle

2.34E-02

P06493, O60566, P33981

CDK1, BUB1B, TTK

Clopidogrel

hsa04114

Oocyte meiosis

1.33E-02

P51812, Q02750, P16298, Q17RY0

RPS6KA3, MAP2K1, PPP3CB, CPEB4

Clopidogrel

hsa04115

p53 signaling pathway

1.47E-04

Q7LG56, P31350, Q9HA38, P06493, P04637

RRM2B, RRM2, ZMAT3, CDK1, TP53

Clopidogrel

hsa04120

Ubiquitin mediated proteolysis

3.44E-02

Q14145, Q13042, P62837, Q15751

KEAP1, CDC16, UBE2D2, HERC1

Clopidogrel

hsa04145

Phagosome

3.99E-02

P05164, P78380, P35443, P13765

MPO, OLR1, THBS4, HLA-DOB

Clopidogrel

hsa04146

Peroxisome

4.83E-02

O96011, P56589, Q9UKG9, O75521

PEX11B, PEX3, CROT, ECI2

Clopidogrel

hsa04150

mTOR signaling pathway

3.60E-02

Q02750, Q9NQL2, P51812

MAP2K1, RRAGD, RPS6KA3

Clopidogrel

hsa04211

Longevity regulating pathway

1.18E-02

Q12778, Q9UEF7, Q96KQ7

FOXO1, KL, EHMT2

Clopidogrel

hsa04213

Longevity regulating pathway - multiple species

3.85E-02

P42338, Q9Y4H2, P11142, Q13547

PIK3CB, IRS2, HSPA8, HDAC1

Clopidogrel

hsa04217

Necroptosis

2.34E-05

P01375, P01568, P48023, Q13489, Q13546, P42224, Q14765, P08238, Q6FI13, Q99878, Q93077, O43633, Q08752

TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT1, STAT4, HSP90AB1, H2AC18; H2AC19, H2AC14, HIST1H2AC, CHMP2A, PPID

Clopidogrel

hsa04370

VEGF signaling pathway

2.68E-03

P16298, Q05397, Q02750

PPP3CB, PTK2, MAP2K1

Clopidogrel

hsa04530

Tight junction

3.29E-02

P16989, P56750, Q14247

CSDA, CLDN17, CTTN

Clopidogrel

hsa04612

Antigen processing and presentation

1.31E-03

P13765, P26715, P26717, Q07444, Q13241, P01732

HLA-DOB, KLRC1, KLRC2, KLRC3, KLRD1, CD8A

Clopidogrel

hsa04613

Neutrophil extracellular trap formation

2.18E-03

P04908, Q93077, P62807, O60814, P68431, O43315, Q16539

H2AC4; H2AC8, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, AQP9, MAPK14

Clopidogrel

hsa04620

Toll-like receptor signaling pathway

4.16E-02

Q13546, P01568

RIPK1, IFNA21

Clopidogrel

hsa04621

NOD-like receptor signaling pathway

4.72E-02

P01568, Q13489, Q13546

IFNA21, BIRC3, RIPK1

Clopidogrel

hsa04622

RIG-I-like receptor signaling pathway

2.39E-02

P01568, Q13546

IFNA21, RIPK1

Clopidogrel

hsa04623

Cytosolic DNA-sensing pathway

2.63E-04

P01568, Q13546, P25963

IFNA21, RIPK1, NFKBIA

Clopidogrel

hsa04640

Hematopoietic cell lineage

2.45E-04

P14778, P27930, P11215, P25063, P07766, P01732, P09564, P13765, P09603

IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7, HLA-DOB, CSF1

Clopidogrel

hsa04650

Natural killer cell mediated cytotoxicity

1.02E-08

P16298, P50591, P19174, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, P26717, Q07444, P26715

PPP3CB, TNFSF10, PLCG1, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, KLRC2, KLRC3, KLRC1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P11511	CYP19A1	Aromatase	P16298	PPP3CB	Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	0.706
P11511	CYP19A1	Aromatase	P50591	TNFSF10	Tumor necrosis factor ligand superfamily member 10	0.701
Q13547	HDAC1	Histone deacetylase 1	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.7
Q13547	HDAC1	Histone deacetylase 1	P06239	LCK	Tyrosine-protein kinase Lck	0.811
O14626	GPR171	Probable G-protein coupled receptor 171	P06239	LCK	Tyrosine-protein kinase Lck	0.864
Q13547	HDAC1	Histone deacetylase 1	O60880	SH2D1A	SH2 domain-containing protein 1A	0.786
O14626	GPR171	Probable G-protein coupled receptor 171	O60880	SH2D1A	SH2 domain-containing protein 1A	0.92
Q13547	HDAC1	Histone deacetylase 1	P20963	CD247	T-cell surface glycoprotein CD3 zeta chain	0.87
O14626	GPR171	Probable G-protein coupled receptor 171	P20963	CD247	T-cell surface glycoprotein CD3 zeta chain	0.898
Q13547	HDAC1	Histone deacetylase 1	P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	-0.774
P11511	CYP19A1	Aromatase	Q02750	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1	0.783
Q13547	HDAC1	Histone deacetylase 1	Q13241	KLRD1	Natural killer cells antigen CD94	0.807
O14626	GPR171	Probable G-protein coupled receptor 171	Q13241	KLRD1	Natural killer cells antigen CD94	0.809
Q13547	HDAC1	Histone deacetylase 1	P26718	KLRK1	NKG2-D type II integral membrane protein	0.772
O14626	GPR171	Probable G-protein coupled receptor 171	P26718	KLRK1	NKG2-D type II integral membrane protein	0.818
Q13547	HDAC1	Histone deacetylase 1	O14931	NCR3	Natural cytotoxicity triggering receptor 3	0.735
O14626	GPR171	Probable G-protein coupled receptor 171	O14931	NCR3	Natural cytotoxicity triggering receptor 3	0.765
O14626	GPR171	Probable G-protein coupled receptor 171	P26717	KLRC2	NKG2-C type II integral membrane protein	0.826
O14626	GPR171	Probable G-protein coupled receptor 171	Q07444	KLRC3	NKG2-E type II integral membrane protein	0.761
O14626	GPR171	Probable G-protein coupled receptor 171	P26715	KLRC1	NKG2-A/NKG2-B type II integral membrane protein	0.826

Clopidogrel

hsa04658

Th1 and Th2 cell differentiation

6.96E-09

Q04759, P07766, P20963, P19174, P06239, Q14765, Q9UL17, P14784, P13765, Q13761

PRKCQ, CD3E, CD247, PLCG1, LCK, STAT4, TBX21, IL2RB, HLA-DOB, RUNX3

Clopidogrel

hsa04659

Th17 cell differentiation

1.76E-06

Q04759, P19174, P06239, P14784, P13765, P14778, Q9HBE5, Q9UL17, P07766, P20963

PRKCQ, PLCG1, LCK, IL2RB, HLA-DOB, IL1R1, IL21R, TBX21, CD3E, CD247

Clopidogrel

hsa04660

T cell receptor signaling pathway

1.19E-05

Q04759, P42338, Q08881, P19174, P07766, P20963, P01732, Q13191, P06239

PRKCQ, PIK3CB, ITK, PLCG1, CD3E, CD247, CD8A, CBLB, LCK

Clopidogrel

hsa04714

Thermogenesis

5.21E-03

Q16539, P33121, Q16718, O14521

MAPK14, ACSL1, NDUFA5, SDHD

Clopidogrel

hsa04720

Long-term potentiation

1.38E-02

P16298, P51812, Q02750

PPP3CB, RPS6KA3, MAP2K1

Clopidogrel

hsa04721

Synaptic vesicle cycle

3.15E-02

Q13488, P31645

TCIRG1, SLC6A4

Clopidogrel

hsa04722

Neurotrophin signaling pathway

3.27E-02

P49841, O43524, P48023

GSK3B, FOXO3, FASLG

Clopidogrel

hsa04750

Inflammatory mediator regulation of TRP channels

9.21E-04

P14778, P22694, P19174, P42338, P24723, Q04759

IL1R1, PRKACB, PLCG1, PIK3CB, PRKCH, PRKCQ

Clopidogrel

hsa04913

Ovarian steroidogenesis

2.72E-02

P42330, P22694

AKR1C3, PRKACB

Clopidogrel

hsa04914

Progesterone-mediated oocyte maturation

2.94E-02

Q17RY0, P51812, Q02750

CPEB4, RPS6KA3, MAP2K1

Clopidogrel

hsa04923

Regulation of lipolysis in adipocytes

2.24E-02

P07550, P42338, Q9Y4H2

ADRB2, PIK3CB, IRS2

Clopidogrel

hsa04932

Non-alcoholic fatty liver disease

2.44E-03

P01375, P49841, P48023, Q16718, O14521

TNF, GSK3B, FASLG, NDUFA5, SDHD

Clopidogrel

hsa04940

Type I diabetes mellitus

1.87E-02

P48023, P01375

FASLG, TNF

Clopidogrel

hsa04973

Carbohydrate digestion and absorption

1.29E-02

O43451, P42338

MGAM, PIK3CB

Clopidogrel

hsa04975

Fat digestion and absorption

2.80E-02

O14494

PLPP1

Clopidogrel

hsa04976

Bile secretion

3.32E-02

O43315, P08183

AQP9, ABCB1

Clopidogrel

hsa05014

Amyotrophic lateral sclerosis

2.72E-02

P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629

TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7

Clopidogrel

hsa05016

Huntington disease

2.46E-05

Q9GZM3, P52435, Q9NYC9

POLR2J2, POLR2J, DNAH9

Clopidogrel

hsa05020

Prion disease

3.80E-02

Q16718, O14521, P49841, Q16539

NDUFA5, SDHD, GSK3B, MAPK14

Clopidogrel

hsa05022

Pathways of neurodegeneration - multiple diseases

1.24E-02

P49841, Q16718, O14521, Q13561, Q16539, Q08752

GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPID

Clopidogrel

hsa05034

Alcoholism

2.89E-03

Q93077, P62807, O60814, P68431

HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12

Clopidogrel

hsa05100

Bacterial invasion of epithelial cells

4.50E-02

Q92529

SHC3

Clopidogrel

hsa05120

Epithelial cell signaling in Helicobacter pylori infection

2.78E-03

P09341, P19875, P19174, P25024, P25025

CXCL1, CXCL2, PLCG1, CXCR1, CXCR2

Clopidogrel

hsa05132

Salmonella infection

9.85E-03

Q13546, Q13489, O60282, P68371

RIPK1, BIRC3, KIF5C, TUBB2C

Clopidogrel

hsa05134

Legionellosis

1.29E-02

P11215, P11142, P09341, P19875

ITGAM, HSPA8, CXCL1, CXCL2

Clopidogrel

hsa05140

Leishmaniasis

1.56E-02

P14598, P42224, P25963, P29350, Q15080

NCF1, STAT1, NFKBIA, PTPN6, NCF4

Clopidogrel

hsa05143

African trypanosomiasis

2.72E-02

P01375, P48023

TNF, FASLG

Clopidogrel

hsa05146

Amoebiasis

5.20E-07

P09341, P19875, P14778, P27930, P42338, P11215, P05089, P22694, P12814, P08311

CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSG

Clopidogrel

hsa05150

Staphylococcus aureus infection

4.02E-03

P21462, O75015, Q14532, P59665, P59666, P12838

FPR1, FCGR3B, KRT32, DEFA1; DEFA1B, DEFA3, DEFA4

Clopidogrel

hsa05160

Hepatitis C

1.27E-02

P60033, P49841, P01375, P48023

CD81, GSK3B, TNF, FASLG

Clopidogrel

hsa05167

Kaposi sarcoma-associated herpesvirus infection

1.94E-02

P62879, P16298, Q02750, P0CG47

GNB2, PPP3CB, MAP2K1, UBB

Clopidogrel

hsa05168

Herpes simplex virus 1 infection

3.38E-03

P25963, P01568, Q05823, P42224, Q07955, Q13243, Q13489, Q13398, Q9HCX3, P52738, O75820, Q9UDV6

NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS5, BIRC3, ZNF211, ZNF304, ZNF140, ZNF189, ZNF212

Clopidogrel

hsa05170

Human immunodeficiency virus 1 infection

6.02E-03

Q02750, P62879, P16298, Q05397, P20333

MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1B

Clopidogrel

hsa05202

Transcriptional misregulation in cancer

1.79E-02

Q15532, P14923, O15550, P04637, P05164

SS18, JUP, UTX, TP53, MPO

Clopidogrel

hsa05203

Viral carcinogenesis

4.85E-02

Q15283, P62807, O60814

RASA2, HIST1H2BC, H2BC12

Clopidogrel

hsa05204

Chemical carcinogenesis

1.48E-02

P78417, P11712

GSTO1, CYP2C9

Clopidogrel

hsa05213

Endometrial cancer

3.79E-02

O15169, Q02750

AXIN1, MAP2K1

Clopidogrel

hsa05226

Gastric cancer

3.79E-02

Q02750, O15169

MAP2K1, AXIN1

Clopidogrel

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

6.47E-04

P42338, P19174, P07766, P20963, P06239, Q04759

PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQ

Clopidogrel

hsa05310

Asthma

2.72E-02

P13765, P12724

HLA-DOB, RNASE3

Clopidogrel

hsa05321

Inflammatory bowel disease

2.22E-03

P13765, Q14765, Q9UL17, Q9HBE5

HLA-DOB, STAT4, TBX21, IL21R

Clopidogrel

hsa05322

Systemic lupus erythematosus

1.31E-04

P09871, Q93077, P62807, O60814, P68431

C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12

Clopidogrel

hsa05323

Rheumatoid arthritis

3.51E-03

P09603, P13765, P09341, P19875

CSF1, HLA-DOB, CXCL1, CXCL2

Clopidogrel

hsa05330

Allograft rejection

2.72E-02

P48023, P01375

FASLG, TNF

Clopidogrel

hsa05332

Graft-versus-host disease

8.05E-04

P13765, P48023, P01375, P26715, Q13241

HLA-DOB, FASLG, TNF, KLRC1, KLRD1

Clopidogrel

hsa05340

Primary immunodeficiency

2.86E-02

P01732, P07766, P06239

CD8A, CD3E, LCK

Clopidogrel

hsa05415

Diabetic cardiomyopathy

4.54E-04

P17252, P14598, Q15080, Q16718, O14521, Q16539, P49841, P04406

PRKCA, NCF1, NCF4, NDUFA5, SDHD, MAPK14, GSK3B, GAPDH

Community members of Clopidogrel (S_DC: 5.02)

UniProtAC

Gene Name

Protein Name

Reported/
Predicted

S_PV

SLC6A4

SodiumNonedependent serotonin transporter

Predicted

0.0477

0.0203

2.0442

P14416

DRD2

D(2) dopamine receptor

Predicted

0.0604

0.4779

2.5081

P22001

KCNA3

Potassium voltageNonegated channel subfamily A member 3

Predicted

0.1396

0.5055

1.0809

Q9UBU7

DBF4

Protein DBF4 homolog A

Predicted

0.0075

0.1961

0.259

0.655

P11712

CYP2C9

Cytochrome P450 2C9

Predicted

0.0106

0.1524

2.1577

Q96EB6

SIRT1

NADNonedependent protein deacetylase sirtuinNone1

Predicted

0.2865

0.4571

0.5784

1.6358

P08235

NR3C2

Mineralocorticoid receptor

Predicted

0.1855

0.0137

2.1064

P11511

CYP19A1

Aromatase

Predicted

0.8156

0.1588

2.5666

P21589

NT5E

5'Nonenucleotidase

Predicted

0.2924

0.0855

0.1539

0.4711

Q13133

NR1H3

Oxysterols receptor LXRNonealpha

Predicted

0.0162

0.439

0.2086

1.0947

Q13547

HDAC1

Histone deacetylase 1

Predicted

0.0447

0.986

3.0084

P09960

LTA4H

Leukotriene ANone4 hydrolase

Predicted

0.277

0.9519

0.1565

2.1988

P04818

TYMS

Thymidylate synthase

Predicted

0.4553

0.2706

0.1893

0.9582

O14626

GPR171

Probable GNoneprotein coupled receptor 171

Predicted

0.0646

0.0183

0.0689

PharmaCoNets of Clopidogrel (SPCN: 57.13 )

Clopidogrel regulated-network (SDN: 11.38)

Community members of Clopidogrel (SDC: 5.02)

PharmaCoNets of Clopidogrel (S_PCN: 57.13 )

Clopidogrel regulated-network (S_DN: 11.38)

Community members of Clopidogrel (S_DC: 5.02)