PharmaCoNets of Chlorpheniramine (SPCN: 114.93 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Chlorpheniraminehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Chlorpheniraminehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Chlorpheniraminehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Chlorpheniraminehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Chlorpheniraminehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Chlorpheniraminehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Chlorpheniraminehsa00600Sphingolipid metabolism4.77E-023Q9BX95, O14494, P06280SGPP1, PLPP1, GLAMore
Chlorpheniraminehsa00604Glycosphingolipid biosynthesis - ganglio series2.87E-033P06865, O15466, Q9H4F1HEXA, ST8SIA5, ST6GALNAC4More
Chlorpheniraminehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Chlorpheniraminehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Chlorpheniraminehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Chlorpheniraminehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Chlorpheniraminehsa00983Drug metabolism - other enzymes3.09E-043P04183, P32320, P05164TK1, CDA, MPOMore
Chlorpheniraminehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Chlorpheniraminehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Chlorpheniraminehsa01240Biosynthesis of cofactors2.52E-022Q9BQB6, P14550VKORC1, AKR1A1More
Chlorpheniraminehsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Chlorpheniraminehsa01522Endocrine resistance2.16E-021P04049RAF1More
Chlorpheniraminehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Chlorpheniraminehsa03010Ribosome1.88E-026P62753, P25398, P32969, P62829, P18077, P36578RPS6, RPS12, RPL9, RPL23, RPL35A, RPL4More
Chlorpheniraminehsa03013RNA transport2.12E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Chlorpheniraminehsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Chlorpheniraminehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Chlorpheniraminehsa03050Proteasome1.21E-021P28074PSMB5More
Chlorpheniraminehsa03320PPAR signaling pathway4.33E-022Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Chlorpheniraminehsa03410Base excision repair2.52E-022P49005, P29372POLD2, MPGMore
Chlorpheniraminehsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Chlorpheniraminehsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Chlorpheniraminehsa04014Ras signaling pathway3.65E-021P04049RAF1More
Chlorpheniraminehsa04015Rap1 signaling pathway2.99E-021P04049RAF1More
Chlorpheniraminehsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Chlorpheniraminehsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Chlorpheniraminehsa04062Chemokine signaling pathway3.98E-021P04049RAF1More
Chlorpheniraminehsa04064NF-kappa B signaling pathway1.60E-028P10415, O00463, Q04759, Q9UDY8, Q16548, Q13315, P24522, P09341BCL2, TRAF5, PRKCQ, MALT1, BCL2A1, ATM, GADD45A, CXCL1More
Chlorpheniraminehsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Chlorpheniraminehsa04071Sphingolipid signaling pathway8.30E-069P04049, P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2RAF1, PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2More
Chlorpheniraminehsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Chlorpheniraminehsa04080Neuroactive ligand-receptor interaction2.16E-039P08311, P28472, Q15722, P21453, Q9H228, O00398, P21730, Q16581, P07550CTSG, GABRB3, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, C3AR1, ADRB2More
Chlorpheniraminehsa04114Oocyte meiosis6.23E-035Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Chlorpheniraminehsa04115p53 signaling pathway3.98E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Chlorpheniraminehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Chlorpheniraminehsa04140Autophagy - animal2.82E-021P04049RAF1More
Chlorpheniraminehsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Chlorpheniraminehsa04145Phagosome3.82E-038Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4More
Chlorpheniraminehsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Chlorpheniraminehsa04210Apoptosis5.97E-0411Q13315, P10415, O76075, P01375, Q9NR28, P24522, Q16548, P43234, P18848, Q14643, P04049ATM, BCL2, DFFB, TNF, DIABLO, GADD45A, BCL2A1, CTSO, ATF4, ITPR1, RAF1More
Chlorpheniraminehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Chlorpheniraminehsa04217Necroptosis4.24E-0510P01375, P48023, Q14765, P07900, P15104, P05141, P01584, P0C0S5, Q99878, Q13557TNF, FASLG, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC14, CAMK2DMore
Chlorpheniraminehsa04218Cellular senescence2.49E-021P04049RAF1More
Chlorpheniraminehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Chlorpheniraminehsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Chlorpheniraminehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Chlorpheniraminehsa04360Axon guidance2.49E-021P04049RAF1More
Chlorpheniraminehsa04370VEGF signaling pathway2.77E-044P16298, Q05397, Q02750, P04049PPP3CB, PTK2, MAP2K1, RAF1More
Chlorpheniraminehsa04371Apelin signaling pathway2.65E-021P04049RAF1More
Chlorpheniraminehsa04510Focal adhesion3.48E-021P04049RAF1More
Chlorpheniraminehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Chlorpheniraminehsa04540Gap junction1.33E-021P04049RAF1More
Chlorpheniraminehsa04550Signaling pathways regulating pluripotency of stem cells9.61E-034Q13873, P04049, Q02750, Q86SE9BMPR2, RAF1, MAP2K1, PCGF5More
Chlorpheniraminehsa04610Complement and coagulation cascades2.78E-031P0C0L4C4AMore
Chlorpheniraminehsa04612Antigen processing and presentation2.09E-048P13765, P48382, Q14953, P26715, P26717, Q13241, P01732, P01375HLA-DOB, RFX5, KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Chlorpheniraminehsa04613Neutrophil extracellular trap formation1.62E-0612P04049, P11215, Q13547, P04908, Q93077, P58876, P62807, Q16778, O60814, P68431, O43315, Q16539RAF1, ITGAM, HDAC1, H2AC4; H2AC8, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, AQP9, MAPK14More
Chlorpheniraminehsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Chlorpheniraminehsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Chlorpheniraminehsa04650Natural killer cell mediated cytotoxicity5.84E-0611P16298, P50591, P01375, P20963, Q02750, P04049, Q13241, P26718, P26717, Q14953, P26715PPP3CB, TNFSF10, TNF, CD247, MAP2K1, RAF1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Chlorpheniraminehsa04657IL-17 signaling pathway2.73E-047P07900, P49841, P19875, P14780, P80188, P01375, P01584HSP90AA1, GSK3B, CXCL2, MMP9, LCN2, TNF, IL1BMore
Chlorpheniraminehsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Chlorpheniraminehsa04662B cell receptor signaling pathway9.95E-031P04049RAF1More
Chlorpheniraminehsa04664Fc epsilon RI signaling pathway1.16E-021P04049RAF1More
Chlorpheniraminehsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Chlorpheniraminehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Chlorpheniraminehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Chlorpheniraminehsa04720Long-term potentiation4.88E-034P16298, P51812, Q02750, P04049PPP3CB, RPS6KA3, MAP2K1, RAF1More
Chlorpheniraminehsa04722Neurotrophin signaling pathway7.10E-034P04049, P49841, O43524, P48023RAF1, GSK3B, FOXO3, FASLGMore
Chlorpheniraminehsa04725Cholinergic synapse4.83E-024P22694, Q14643, P18848, P10415PRKACB, ITPR1, ATF4, BCL2More
Chlorpheniraminehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Chlorpheniraminehsa04730Long-term depression1.16E-021P04049RAF1More
Chlorpheniraminehsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Chlorpheniraminehsa04910Insulin signaling pathway2.51E-034P22694, P06737, P04049, P49841PRKACB, PYGL, RAF1, GSK3BMore
Chlorpheniraminehsa04912GnRH signaling pathway1.82E-021P04049RAF1More
Chlorpheniraminehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Chlorpheniraminehsa04914Progesterone-mediated oocyte maturation1.91E-035Q17RY0, Q9Y6D9, P51812, Q02750, P04049CPEB4, MAD1L1, RPS6KA3, MAP2K1, RAF1More
Chlorpheniraminehsa04915Estrogen signaling pathway3.15E-026P14780, P22694, P04049, P18848, Q14643, P10415MMP9, PRKACB, RAF1, ATF4, ITPR1, BCL2More
Chlorpheniraminehsa04916Melanogenesis1.33E-021P04049RAF1More
Chlorpheniraminehsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Chlorpheniraminehsa04918Thyroid hormone synthesis3.50E-023P22694, P18848, Q14643PRKACB, ATF4, ITPR1More
Chlorpheniraminehsa04919Thyroid hormone signaling pathway6.83E-045P49841, P04049, P22694, O60244, Q9NVC6GSK3B, RAF1, PRKACB, MED14, MED17More
Chlorpheniraminehsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Chlorpheniraminehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Chlorpheniraminehsa04926Relaxin signaling pathway6.24E-035P18848, P22694, P14780, P04049, P30679ATF4, PRKACB, MMP9, RAF1, GNA15More
Chlorpheniraminehsa04927Cortisol synthesis and secretion4.44E-043Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Chlorpheniraminehsa04928Parathyroid hormone synthesis, secretion and action9.56E-036Q14643, P22694, P23771, P04049, P18848, P10415ITPR1, PRKACB, GATA3, RAF1, ATF4, BCL2More
Chlorpheniraminehsa04929GnRH secretion4.98E-031P04049RAF1More
Chlorpheniraminehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Chlorpheniraminehsa04932Non-alcoholic fatty liver disease6.73E-059P01375, P49841, P18848, P48023, P01584, P13073, O15239, Q16718, O14521TNF, GSK3B, ATF4, FASLG, IL1B, COX4I1, NDUFA1, NDUFA5, SDHDMore
Chlorpheniraminehsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Chlorpheniraminehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Chlorpheniraminehsa04961Endocrine and other factor-regulated calcium reabsorption2.68E-023P20020, Q9UEF7, P17252ATP2B1, KL, PRKCAMore
Chlorpheniraminehsa04966Collecting duct acid secretion1.68E-022P02730, P00918SLC4A1, CA2More
Chlorpheniraminehsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Chlorpheniraminehsa04972Pancreatic secretion2.68E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Chlorpheniraminehsa04976Bile secretion1.67E-033O43315, P22694, P08183AQP9, PRKACB, ABCB1More
Chlorpheniraminehsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Chlorpheniraminehsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Chlorpheniraminehsa05017Spinocerebellar ataxia2.43E-021P28074PSMB5More
Chlorpheniraminehsa05020Prion disease3.73E-0411P13591, P01584, P11142, O15239, Q16718, O14521, P13073, P18848, P05141, P49841, Q16539NCAM1, IL1B, HSPA8, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, SLC25A5, GSK3B, MAPK14More
Chlorpheniraminehsa05022Pathways of neurodegeneration - multiple diseases1.47E-0312P49841, O15239, Q16718, O14521, P13073, P18848, Q13561, P05141, Q16539, P01584, Q08752, Q13557GSK3B, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, DCTN2, SLC25A5, MAPK14, IL1B, PPID, CAMK2DMore
Chlorpheniraminehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Chlorpheniraminehsa05034Alcoholism1.81E-068Q13547, P04049, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, RAF1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Chlorpheniraminehsa05100Bacterial invasion of epithelial cells2.85E-023Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Chlorpheniraminehsa05132Salmonella infection5.10E-0312P51617, P04049, Q9UJU2, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, Q13509, P68371IRAK1, RAF1, LEF1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, TUBB3, TUBB2CMore
Chlorpheniraminehsa05133Pertussis4.94E-021P0C0L4C4AMore
Chlorpheniraminehsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Chlorpheniraminehsa05135Yersinia infection3.29E-024Q05397, P51812, Q02750, Q96JJ3PTK2, RPS6KA3, MAP2K1, ELMO2More
Chlorpheniraminehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Chlorpheniraminehsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Chlorpheniraminehsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Chlorpheniraminehsa05152Tuberculosis1.40E-029P04049, Q13488, P48382, P25208, O60603, P10415, P01568, Q9UDY8, P51617RAF1, TCIRG1, RFX5, NFYB, TLR2, BCL2, IFNA21, MALT1, IRAK1More
Chlorpheniraminehsa05160Hepatitis C1.40E-035P60033, P04049, P49841, P01375, P48023CD81, RAF1, GSK3B, TNF, FASLGMore
Chlorpheniraminehsa05161Hepatitis B1.99E-021P04049RAF1More
Chlorpheniraminehsa05162Measles4.02E-023P11142, P01584, Q9NP90HSPA8, IL1B, RAB9BMore
Chlorpheniraminehsa05163Human cytomegalovirus infection4.98E-021P04049RAF1More
Chlorpheniraminehsa05164Influenza A3.65E-021P04049RAF1More
Chlorpheniraminehsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Chlorpheniraminehsa05170Human immunodeficiency virus 1 infection5.63E-0311P04049, P62873, P17252, Q13546, Q14643, P01568, P51617, O60603, Q13315, P10415, Q9Y6Q5RAF1, GNB1, PRKCA, RIPK1, ITPR1, IFNA21, IRAK1, TLR2, ATM, BCL2, AP1M2More
Chlorpheniraminehsa05171Coronavirus disease - COVID-199.72E-037P01584, P62753, P25398, P36578, P32969, P18077, P62829IL1B, RPS6, RPS12, RPL4, RPL9, RPL35A, RPL23More
Chlorpheniraminehsa05202Transcriptional misregulation in cancer1.12E-0420Q12778, Q15532, Q13315, P14780, P27930, P14923, Q15744, Q16548, P11215, Q13489, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, Q13547, P12980, P24522FOXO1, SS18, ATM, MMP9, IL1R2, JUP, CEBPE, BCL2A1, ITGAM, BIRC3, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, HDAC1, LYL1, GADD45AMore
Chlorpheniraminehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P58876, P62807, Q16778, O60814HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Chlorpheniraminehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Chlorpheniraminehsa05205Proteoglycans in cancer8.14E-0413Q13009, Q14643, O75369, P04049, P14780, P17252, O60603, P01375, P23588, P04628, Q13635, P22694, P08962TIAM1, ITPR1, FLNB, RAF1, MMP9, PRKCA, TLR2, TNF, EIF4B, WNT1, PTCH1, PRKACB, CD63More
Chlorpheniraminehsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Chlorpheniraminehsa05210Colorectal cancer1.66E-021P04049RAF1More
Chlorpheniraminehsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Chlorpheniraminehsa05212Pancreatic cancer1.16E-021P04049RAF1More
Chlorpheniraminehsa05213Endometrial cancer9.95E-031P04049RAF1More
Chlorpheniraminehsa05214Glioma9.95E-031P04049RAF1More
Chlorpheniraminehsa05215Prostate cancer1.33E-021P04049RAF1More
Chlorpheniraminehsa05218Melanoma9.63E-044P09619, Q9GZP0, Q02750, P04049PDGFRB, PDGFD, MAP2K1, RAF1More
Chlorpheniraminehsa05219Bladder cancer4.98E-031P04049RAF1More
Chlorpheniraminehsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Chlorpheniraminehsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Chlorpheniraminehsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Chlorpheniraminehsa05224Breast cancer1.49E-021P04049RAF1More
Chlorpheniraminehsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Chlorpheniraminehsa05226Gastric cancer8.29E-031P04049RAF1More
Chlorpheniraminehsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Chlorpheniraminehsa05231Choline metabolism in cancer1.49E-035Q02750, P04049, P09619, Q9GZP0, O15245MAP2K1, RAF1, PDGFRB, PDGFD, SLC22A1More
Chlorpheniraminehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Chlorpheniraminehsa05321Inflammatory bowel disease1.19E-036P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Chlorpheniraminehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P58876, P62807, Q16778, O60814, P68431C1S, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Chlorpheniraminehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Chlorpheniraminehsa05332Graft-versus-host disease1.91E-056P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Chlorpheniraminehsa05412Arrhythmogenic right ventricular cardiomyopathy3.10E-023Q8IZS8, P54284, P13612CACNA2D3, CACNB3, ITGA4More
Chlorpheniraminehsa05414Dilated cardiomyopathy2.11E-024Q8IZS8, P54284, P13612, P26678CACNA2D3, CACNB3, ITGA4, PLNMore
Chlorpheniraminehsa05415Diabetic cardiomyopathy1.02E-038P05141, O15239, Q16718, O14521, P13073, Q16539, P49841, Q13557SLC25A5, NDUFA1, NDUFA5, SDHD, COX4I1, MAPK14, GSK3B, CAMK2DMore

Community members of Chlorpheniramine (SDC: 5.76)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P31645SLC6A4SodiumNonedependent serotonin transporterReported00.047710.02032.0442
P28074PSMB5Proteasome subunit beta typeNone5Predicted10.28390.47230.54391.6305
O14786NRP1NeuropilinNone1Predicted10.38340.20260.51531.1123
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P04156PRNPMajor prion proteinPredicted00.59090.173700.6429
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P02768ALBAlbuminPredicted10.28480.91110.08572.0502
P05164MPOMyeloperoxidasePredicted10.20350.53680.55021.7255
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
Q9UDY8MALT1MucosaNoneassociated lymphoid tissue lymphoma translocation protein 1Predicted10.05160.1470.55920.8789
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
P30531SLC6A1SodiumNone and chlorideNonedependent GABA transporter 1Predicted10.08890.52020.10471.1894
P48029SLC6A8SodiumNone and chlorideNonedependent creatine transporter 1Predicted10.21610.232800.5737
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)