PharmaCoNets of Ceftriaxone (SPCN: 5.05 )

Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Ceftriaxonehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Ceftriaxonehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Ceftriaxonehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Ceftriaxonehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Ceftriaxonehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Ceftriaxonehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Ceftriaxonehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Ceftriaxonehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Ceftriaxonehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Ceftriaxonehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Ceftriaxonehsa04613Neutrophil extracellular trap formation1.02E-048P11215, Q13547, Q93077, P62807, P58876, Q16778, O60814, P68431ITGAM, HDAC1, HIST1H2AC, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Ceftriaxonehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Ceftriaxonehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Ceftriaxonehsa05034Alcoholism2.05E-057Q13547, Q93077, P62807, P58876, Q16778, O60814, P68431HDAC1, HIST1H2AC, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Ceftriaxonehsa05133Pertussis4.20E-021P0C0L4C4AMore
Ceftriaxonehsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Ceftriaxonehsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Ceftriaxonehsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Ceftriaxonehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P62807, P58876, Q16778, O60814HDAC1, RASA2, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12More
Ceftriaxonehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Ceftriaxonehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P62807, P58876, Q16778, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Ceftriaxonehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More

Community members of Ceftriaxone (SDC: 2.55)

UniProtACGene NameProtein NameReported/
Predicted
DisGeNETSPVSdrugabilitySHiSBiNSDisG
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)