PharmaCoNets of Cefditoren (SPCN: 4.33 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Cefditorenhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Cefditorenhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Cefditorenhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Cefditorenhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Cefditorenhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Cefditorenhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Cefditorenhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Cefditorenhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Cefditorenhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Cefditorenhsa04613Neutrophil extracellular trap formation1.73E-024Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Cefditorenhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Cefditorenhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Cefditorenhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Cefditorenhsa05133Pertussis4.20E-021P0C0L4C4AMore
Cefditorenhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Cefditorenhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Cefditorenhsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Cefditorenhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Cefditorenhsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Cefditorenhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More

Community members of Cefditoren (SDC: 2.68)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)