PharmaCoNets of Carbetocin (SPCN: 8.90 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Carbetocinhsa00072Synthesis and degradation of ketone bodies2.78E-021Q01581HMGCS1More
Carbetocinhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Carbetocinhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Carbetocinhsa00900Terpenoid backbone biosynthesis1.40E-021Q01581HMGCS1More
Carbetocinhsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Carbetocinhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Carbetocinhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Carbetocinhsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Carbetocinhsa04015Rap1 signaling pathway2.26E-023P25116, Q8TEU7, P08514F2R, RAPGEF6, ITGA2BMore
Carbetocinhsa04022cGMP-PKG signaling pathway1.05E-023P24844, Q8WYR1, Q15746MYL9, PIK3R5, MYLKMore
Carbetocinhsa04024cAMP signaling pathway1.40E-023P48058, P25116, P24844GRIA4, F2R, MYL9More
Carbetocinhsa04080Neuroactive ligand-receptor interaction4.15E-022Q01726, P41968MC1R, MC3RMore
Carbetocinhsa04270Vascular smooth muscle contraction4.65E-022Q15746, P24844MYLK, MYL9More
Carbetocinhsa04510Focal adhesion3.36E-023P08514, Q15746, P24844ITGA2B, MYLK, MYL9More
Carbetocinhsa04512ECM-receptor interaction2.44E-022P07359, P08514GP1BA, ITGA2BMore
Carbetocinhsa04514Cell adhesion molecules4.65E-022P16109, O00501SELP, CLDN5More
Carbetocinhsa04530Tight junction1.14E-046Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Carbetocinhsa04610Complement and coagulation cascades2.94E-022P25116, P10909F2R, CLUMore
Carbetocinhsa04611Platelet activation1.59E-055P25116, P08514, Q15746, Q8WYR1, P07359F2R, ITGA2B, MYLK, PIK3R5, GP1BAMore
Carbetocinhsa04613Neutrophil extracellular trap formation1.73E-024Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Carbetocinhsa04724Glutamatergic synapse2.94E-022P48058, Q9NSB8GRIA4, HOMER2More
Carbetocinhsa04810Regulation of actin cytoskeleton1.38E-034P24844, Q15746, P08514, P25116MYL9, MYLK, ITGA2B, F2RMore
Carbetocinhsa04921Oxytocin signaling pathway6.37E-033Q15746, P24844, Q8WYR1MYLK, MYL9, PIK3R5More
Carbetocinhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Carbetocinhsa05130Pathogenic Escherichia coli infection2.51E-023Q14247, O00501, P25116CTTN, CLDN5, F2RMore
Carbetocinhsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Carbetocinhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Carbetocinhsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More

Community members of Carbetocin (SDC: 2.97)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P08514ITGA2BIntegrin alphaNoneIIbPredicted10.07820.32480.7791.4677
Q01726MC1RMelanocyteNonestimulating hormone receptorPredicted10.0470.23750.0110.5095
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)