PharmaCoNets

PharmaCoNets of Calcium-phosphate-dihydrate (S_PCN: 32.32 )

Calcium-phosphate-dihydrate regulated-network (S_DN: 27.87)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Calcium-phosphate-dihydrate

hsa00030

Pentose phosphate pathway

4.66E-02

P60891, P04075, P37837

PRPS1, ALDOA, TALDO1

Calcium-phosphate-dihydrate

hsa00071

Fatty acid degradation

1.72E-02

P11310, O75521, P11766, P33121

ACADM, ECI2, ADH5, ACSL1

Calcium-phosphate-dihydrate

hsa00190

Oxidative phosphorylation

1.49E-02

P13073, O95298, O15239, P12074, P05496

COX4I1, NDUFC2, NDUFA1, COX6A1, ATP5G1

Calcium-phosphate-dihydrate

hsa00220

Arginine biosynthesis

4.33E-02

P05089, P49448

ARG1, GLUD2

Calcium-phosphate-dihydrate

hsa00230

Purine metabolism

4.60E-02

Q13370, P36959, Q13956, P27707

PDE3B, GMPR, PDE6H, DCK

Calcium-phosphate-dihydrate

hsa00240

Pyrimidine metabolism

4.50E-02

P32320, P27707

CDA, DCK

Calcium-phosphate-dihydrate

hsa00430

Taurine and hypotaurine metabolism

4.49E-02

Q14032

BAAT

Calcium-phosphate-dihydrate

hsa00500

Starch and sucrose metabolism

4.66E-02

O43451, P46976, P06737

MGAM, GYG1, PYGL

Calcium-phosphate-dihydrate

hsa00512

Mucin type O-glycan biosynthesis

2.11E-02

O95395, Q8N4A0

GCNT3, GALNT4

Calcium-phosphate-dihydrate

hsa00514

Other types of O-glycan biosynthesis

3.37E-02

P15907, Q8N4A0

ST6GAL1, GALNT4

Calcium-phosphate-dihydrate

hsa00534

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

4.77E-02

Q7LGA3

HS2ST1

Calcium-phosphate-dihydrate

hsa00561

Glycerolipid metabolism

2.29E-02

P51648, P23743

ALDH3A2, DGKA

Calcium-phosphate-dihydrate

hsa00564

Glycerophospholipid metabolism

4.29E-03

Q6P1A2, P23743, P49619, O14494, Q3LIE5

MBOAT5, DGKA, DGKG, PLPP1, ADPRM

Calcium-phosphate-dihydrate

hsa00565

Ether lipid metabolism

4.26E-02

Q8N661

TMEM86B

Calcium-phosphate-dihydrate

hsa00630

Glyoxylate and dicarboxylate metabolism

8.09E-06

O75390, P40925, P40926, P15104

CS, MDH1, MDH2, GLUL

Calcium-phosphate-dihydrate

hsa00670

One carbon pool by folate

3.99E-02

O95954, Q99707

FTCD, MTR

Calcium-phosphate-dihydrate

hsa00760

Nicotinate and nicotinamide metabolism

2.11E-02

P43490, Q13423

PBEF1, NNT

Calcium-phosphate-dihydrate

hsa00790

Folate biosynthesis

1.49E-02

Q92820, P07101

GGH, TH

Calcium-phosphate-dihydrate

hsa00910

Nitrogen metabolism

4.33E-02

P22748, P49448

CA4, GLUD2

Calcium-phosphate-dihydrate

hsa00920

Sulfur metabolism

3.01E-02

O95571

ETHE1

Calcium-phosphate-dihydrate

hsa00970

Aminoacyl-tRNA biosynthesis

8.37E-04

O95363, P54136, P14868

FARS2, RARS1, DARS

Calcium-phosphate-dihydrate

hsa01100

Metabolic pathways

3.95E-02

Q9Y234, Q99707, P29218, P11310, P27707, Q13370, P36959, Q13956, P30043, Q02252, O60701, O14772, O95954, Q02318, P04406, O15466, P09960, Q9P2R7, Q9UHY7, P35573, Q13488, Q16718, Q02809

LIPT1, MTR, IMPA1, ACADM, DCK, PDE3B, GMPR, PDE6H, BLVRB, ALDH6A1, UGDH, FPGT, FTCD, CYP27A1, GAPDH, ST8SIA5, LTA4H, SUCLA2, ENOPH1, AGL, TCIRG1, NDUFA5, PLOD1

Calcium-phosphate-dihydrate

hsa01200

Carbon metabolism

4.29E-02

P04406, O14521, Q9P2R7, Q02252

GAPDH, SDHD, SUCLA2, ALDH6A1

Calcium-phosphate-dihydrate

hsa01521

EGFR tyrosine kinase inhibitor resistance

2.79E-02

P21860, P23458, O43521, P62753

ERBB3, JAK1, BCL2L11, RPS6

Calcium-phosphate-dihydrate

hsa01523

Antifolate resistance

2.71E-02

P01584

IL1B

Calcium-phosphate-dihydrate

hsa01524

Platinum drug resistance

4.45E-02

P10415, Q13489, P78417, P43246

BCL2, BIRC3, GSTO1, MSH2

Calcium-phosphate-dihydrate

hsa02010

ABC transporters

2.60E-04

P45844, Q8IZY2, Q99758

ABCG1, ABCA7, ABCA3

Calcium-phosphate-dihydrate

hsa03010

Ribosome

7.11E-06

P62266, P62753, P39019, P42677, P25398, P32969, P62906, P62917, P62829, Q07020, P62888, P61927, P61513, Q02878, P63173, P36578, P05386, Q9NRX2, P23396

RPS23, RPS6, RPS19, RPS27, RPS12, RPL9, RPL10A, RPL8, RPL23, RPL18, RPL30, RPL37, RPL37A, RPL6, RPL38, RPL4, RPLP1, MRPL17, RPS3

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P13693	TPT1	Translationally-controlled tumor protein	P62266	RPS23	40S ribosomal protein S23	0.801
P13693	TPT1	Translationally-controlled tumor protein	P62753	RPS6	40S ribosomal protein S6	0.773
P25815	S100P	Protein S100-P	P62753	RPS6	40S ribosomal protein S6	0.799
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62753	RPS6	40S ribosomal protein S6	0.77
P13693	TPT1	Translationally-controlled tumor protein	P39019	RPS19	40S ribosomal protein S19	0.71
P25815	S100P	Protein S100-P	P39019	RPS19	40S ribosomal protein S19	0.79
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P39019	RPS19	40S ribosomal protein S19	0.791
P25815	S100P	Protein S100-P	P42677	RPS27	40S ribosomal protein S27	0.724
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P42677	RPS27	40S ribosomal protein S27	0.727
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P25398	RPS12	40S ribosomal protein S12	0.724
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P32969	RPL9	60S ribosomal protein L9	0.814
P13693	TPT1	Translationally-controlled tumor protein	P62906	RPL10A	60S ribosomal protein L10a	0.727
P25815	S100P	Protein S100-P	P62906	RPL10A	60S ribosomal protein L10a	0.754
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62906	RPL10A	60S ribosomal protein L10a	0.737
P25815	S100P	Protein S100-P	P62917	RPL8	60S ribosomal protein L8	0.817
P13693	TPT1	Translationally-controlled tumor protein	P62829	RPL23	60S ribosomal protein L23	0.731
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62829	RPL23	60S ribosomal protein L23	0.72
P25815	S100P	Protein S100-P	Q07020	RPL18	60S ribosomal protein L18	0.764
P13693	TPT1	Translationally-controlled tumor protein	P62888	RPL30	60S ribosomal protein L30	0.721
P13693	TPT1	Translationally-controlled tumor protein	P61927	RPL37	60S ribosomal protein L37	0.81
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61927	RPL37	60S ribosomal protein L37	0.772
P13693	TPT1	Translationally-controlled tumor protein	P61513	RPL37A	60S ribosomal protein L37a	0.846
P25815	S100P	Protein S100-P	P61513	RPL37A	60S ribosomal protein L37a	0.818
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61513	RPL37A	60S ribosomal protein L37a	0.83
P25815	S100P	Protein S100-P	Q02878	RPL6	60S ribosomal protein L6	0.738
P25815	S100P	Protein S100-P	P63173	RPL38	60S ribosomal protein L38	0.79
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63173	RPL38	60S ribosomal protein L38	0.756
P25815	S100P	Protein S100-P	P36578	RPL4	60S ribosomal protein L4	0.84
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P36578	RPL4	60S ribosomal protein L4	0.749
P25815	S100P	Protein S100-P	P05386	RPLP1	60S acidic ribosomal protein P1	0.921
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05386	RPLP1	60S acidic ribosomal protein P1	0.768
P13693	TPT1	Translationally-controlled tumor protein	Q9NRX2	MRPL17	39S ribosomal protein L17, mitochondrial	-0.737
P25815	S100P	Protein S100-P	P23396	RPS3	40S ribosomal protein S3	0.815
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P23396	RPS3	40S ribosomal protein S3	0.758

Calcium-phosphate-dihydrate

hsa03013

RNA transport

1.82E-04

P62826, O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, P63279, P47813, Q14152, O75822, Q14240, Q9Y6A5, Q06787, P51114

RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, UBE2I, EIF1AX, EIF3A, EIF3J, EIF4A2, TACC3, FMR1, FXR1

Calcium-phosphate-dihydrate

hsa03015

mRNA surveillance pathway

3.62E-02

O43148, P61326, P52298

RNMT, MAGOH, NCBP2

Calcium-phosphate-dihydrate

hsa03018

RNA degradation

2.97E-02

Q9Y2L1, Q8IU60

DIS3, DCP2

Calcium-phosphate-dihydrate

hsa03040

Spliceosome

8.47E-10

Q14562, O43143, O60508, P17844, O14776, P08579, O75940, P52298, P09651, Q15365, O75494, Q07955, Q01130, Q13243, P11142, Q9Y2W2, O95777, O43447, O43395, O75643, P61326

DHX8, DHX15, CDC40, DDX5, TCERG1, SNRPB2, SMNDC1, NCBP2, HNRNPA1, PCBP1, FUSIP1, SFRS1, SFRS2, SFRS5, HSPA8, WBP11, LSM8, PPIH, PRPF3, ASCC3L1, MAGOH

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	Q14562	DHX8	ATP-dependent RNA helicase DHX8	0.942
P0DP24	CALM2	Calmodulin-2	Q14562	DHX8	ATP-dependent RNA helicase DHX8	0.942
P0DP25	CALM3	Calmodulin-3	Q14562	DHX8	ATP-dependent RNA helicase DHX8	0.942
P0DP23	CALM1	Calmodulin-1	O43143	DHX15	ATP-dependent RNA helicase DHX15	0.963
P0DP24	CALM2	Calmodulin-2	O43143	DHX15	ATP-dependent RNA helicase DHX15	0.963
P0DP25	CALM3	Calmodulin-3	O43143	DHX15	ATP-dependent RNA helicase DHX15	0.963
P0DP23	CALM1	Calmodulin-1	O60508	CDC40	Pre-mRNA-processing factor 17	0.828
P28676	GCA	Grancalcin	O60508	CDC40	Pre-mRNA-processing factor 17	-0.74
P0DP24	CALM2	Calmodulin-2	O60508	CDC40	Pre-mRNA-processing factor 17	0.828
P0DP25	CALM3	Calmodulin-3	O60508	CDC40	Pre-mRNA-processing factor 17	0.828
P0DP24	CALM2	Calmodulin-2	P17844	DDX5	Probable ATP-dependent RNA helicase DDX5	0.734
P06702	S100A9	Protein S100-A9	O14776	TCERG1	Transcription elongation regulator 1	-0.791
O15182	CETN3	Centrin-3	O14776	TCERG1	Transcription elongation regulator 1	0.758
P0DP23	CALM1	Calmodulin-1	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	0.781
P28676	GCA	Grancalcin	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	-0.776
P0DP24	CALM2	Calmodulin-2	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	0.781
P0DP25	CALM3	Calmodulin-3	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	0.781
P06702	S100A9	Protein S100-A9	O75940	SMNDC1	Survival of motor neuron-related-splicing factor 30	-0.945
O15182	CETN3	Centrin-3	O75940	SMNDC1	Survival of motor neuron-related-splicing factor 30	0.859
O15182	CETN3	Centrin-3	P52298	NCBP2	Nuclear cap-binding protein subunit 2	0.701
P06702	S100A9	Protein S100-A9	P09651	HNRNPA1	Heterogeneous nuclear ribonucleoprotein A1	-0.762
O15182	CETN3	Centrin-3	P09651	HNRNPA1	Heterogeneous nuclear ribonucleoprotein A1	0.757
P0DP24	CALM2	Calmodulin-2	Q15365	PCBP1	Poly(rC)-binding protein 1	0.75
P06702	S100A9	Protein S100-A9	O75494	FUSIP1	Serine/arginine-rich splicing factor 10	-0.856
O15182	CETN3	Centrin-3	O75494	FUSIP1	Serine/arginine-rich splicing factor 10	0.85
P0DP23	CALM1	Calmodulin-1	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P0DP24	CALM2	Calmodulin-2	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P0DP25	CALM3	Calmodulin-3	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P06702	S100A9	Protein S100-A9	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.783
P0DP23	CALM1	Calmodulin-1	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P28676	GCA	Grancalcin	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	-0.737
P0DP24	CALM2	Calmodulin-2	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P0DP25	CALM3	Calmodulin-3	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P0DP23	CALM1	Calmodulin-1	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P28676	GCA	Grancalcin	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	-0.732
P0DP24	CALM2	Calmodulin-2	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P0DP25	CALM3	Calmodulin-3	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P0DP23	CALM1	Calmodulin-1	P11142	HSPA8	Heat shock cognate 71 kDa protein	0.804
P28676	GCA	Grancalcin	P11142	HSPA8	Heat shock cognate 71 kDa protein	-0.739
P0DP24	CALM2	Calmodulin-2	P11142	HSPA8	Heat shock cognate 71 kDa protein	0.804
P0DP25	CALM3	Calmodulin-3	P11142	HSPA8	Heat shock cognate 71 kDa protein	0.804
P28676	GCA	Grancalcin	Q9Y2W2	WBP11	WW domain-binding protein 11	-0.826
P06702	S100A9	Protein S100-A9	O95777	LSM8	U6 snRNA-associated Sm-like protein LSm8	-0.796
O15182	CETN3	Centrin-3	O95777	LSM8	U6 snRNA-associated Sm-like protein LSm8	0.723
P0DP23	CALM1	Calmodulin-1	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	0.748
P28676	GCA	Grancalcin	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	-0.732
P0DP24	CALM2	Calmodulin-2	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	0.748
P0DP25	CALM3	Calmodulin-3	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	0.748
P06702	S100A9	Protein S100-A9	O43395	PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3	-0.709
P28676	GCA	Grancalcin	O75643	ASCC3L1	U5 small nuclear ribonucleoprotein 200 kDa helicase	-0.79
O15182	CETN3	Centrin-3	P61326	MAGOH	Protein mago nashi homolog	0.811

Calcium-phosphate-dihydrate

hsa03050

Proteasome

5.53E-03

P43686, P28070

PSMC4, PSMB4

Calcium-phosphate-dihydrate

hsa03060

Protein export

3.59E-02

P37108, Q15005

SRP14, SPCS2

Calcium-phosphate-dihydrate

hsa03320

PPAR signaling pathway

1.75E-03

Q6PCB7, O00767, Q9UNU6, Q02318

SLC27A1, SCD, CYP8B1, CYP27A1

Calcium-phosphate-dihydrate

hsa03450

Non-homologous end-joining

3.15E-02

P13010

XRCC5

Calcium-phosphate-dihydrate

hsa03460

Fanconi anemia pathway

3.70E-03

Q9NPI8, O60673, Q9UNA4

FANCF, REV3L, POLI

Calcium-phosphate-dihydrate

hsa04014

Ras signaling pathway

2.65E-03

P31751, P20827, P49767, Q13009, P17252, Q15311, P0DP23, P62873, P19174

AKT2, EFNA1, VEGFC, TIAM1, PRKCA, RALBP1, CALM1, GNB1, PLCG1

Calcium-phosphate-dihydrate

hsa04015

Rap1 signaling pathway

8.67E-04

P20827, P49767, P25116, Q8TEU7, Q13009, Q08828, P51828, P31751, P0DP23, P08514, P17252, P19174

EFNA1, VEGFC, F2R, RAPGEF6, TIAM1, ADCY1, ADCY7, AKT2, CALM1, ITGA2B, PRKCA, PLCG1

Calcium-phosphate-dihydrate

hsa04020

Calcium signaling pathway

4.80E-10

P27987, Q96DU7, Q08828, P45880, Q13557, P17252, P21860, O15399, P19174, P61073, P0DP23, P05141, P51828, P63092, P23634, P49767

ITPKB, ITPKC, ADCY1, VDAC2, CAMK2D, PRKCA, ERBB3, GRIN2D, PLCG1, CXCR4, CALM1, SLC25A5, ADCY7, GNAS, ATP2B4, VEGFC

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P27987	ITPKB	Inositol-trisphosphate 3-kinase B	0.701
P0DP24	CALM2	Calmodulin-2	P27987	ITPKB	Inositol-trisphosphate 3-kinase B	0.701
P0DP25	CALM3	Calmodulin-3	P27987	ITPKB	Inositol-trisphosphate 3-kinase B	0.701
P13693	TPT1	Translationally-controlled tumor protein	Q96DU7	ITPKC	Inositol-trisphosphate 3-kinase C	-0.708
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q96DU7	ITPKC	Inositol-trisphosphate 3-kinase C	-0.766
P13693	TPT1	Translationally-controlled tumor protein	Q08828	ADCY1	Adenylate cyclase type 1	0.88
P0DP23	CALM1	Calmodulin-1	Q08828	ADCY1	Adenylate cyclase type 1	0.725
P0DP24	CALM2	Calmodulin-2	Q08828	ADCY1	Adenylate cyclase type 1	0.711
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q08828	ADCY1	Adenylate cyclase type 1	0.714
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
P13693	TPT1	Translationally-controlled tumor protein	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.774
P0DP24	CALM2	Calmodulin-2	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.786
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.861
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP25	CALM3	Calmodulin-3	P17252	PRKCA	Protein kinase C alpha type	-0.776
P13693	TPT1	Translationally-controlled tumor protein	P21860	ERBB3	Receptor tyrosine-protein kinase erbB-3	-0.729
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P21860	ERBB3	Receptor tyrosine-protein kinase erbB-3	-0.753
P0DP23	CALM1	Calmodulin-1	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP24	CALM2	Calmodulin-2	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP25	CALM3	Calmodulin-3	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP23	CALM1	Calmodulin-1	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP24	CALM2	Calmodulin-2	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP25	CALM3	Calmodulin-3	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP24	CALM2	Calmodulin-2	P61073	CXCR4	C-X-C chemokine receptor type 4	0.759
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61073	CXCR4	C-X-C chemokine receptor type 4	0.77
P0DP23	CALM1	Calmodulin-1	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P0DP23	CALM1	Calmodulin-1	1
P0DP25	CALM3	Calmodulin-3	P0DP23	CALM1	Calmodulin-1	1
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
P0DP23	CALM1	Calmodulin-1	P51828	ADCY7	Adenylate cyclase type 7	0.719
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702
P0DP23	CALM1	Calmodulin-1	P23634	ATP2B4	Plasma membrane calcium-transporting ATPase 4	0.793
P0DP24	CALM2	Calmodulin-2	P23634	ATP2B4	Plasma membrane calcium-transporting ATPase 4	0.793
P0DP25	CALM3	Calmodulin-3	P23634	ATP2B4	Plasma membrane calcium-transporting ATPase 4	0.793
P0DP23	CALM1	Calmodulin-1	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP24	CALM2	Calmodulin-2	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP25	CALM3	Calmodulin-3	P49767	VEGFC	Vascular endothelial growth factor C	-0.84

Calcium-phosphate-dihydrate

hsa04024

cAMP signaling pathway

4.08E-04

Q08828, P51828, P31751, P0DP23, P23634, Q13557, Q13370, P48058, O15399, P25116, P24844, Q13009

ADCY1, ADCY7, AKT2, CALM1, ATP2B4, CAMK2D, PDE3B, GRIA4, GRIN2D, F2R, MYL9, TIAM1

Calcium-phosphate-dihydrate

hsa04060

Cytokine-cytokine receptor interaction

4.07E-03

P32927, P27930, P01584, P61073, P25024, P25025, Q9UBD3, P47992, P20333, P01375, P09341, Q99731, P18510, Q93038

CSF2RB, IL1R2, IL1B, CXCR4, CXCR1, CXCR2, XCL2, XCL1, TNFRSF1B, TNF, CXCL1, CCL19, IL1RN, TNFRSF25

Calcium-phosphate-dihydrate

hsa04061

Viral protein interaction with cytokine and cytokine receptor

3.95E-03

Q99731, P09341, P25024, P25025, P61073, P47992, Q9UBD3, P20333, P01375

CCL19, CXCL1, CXCR1, CXCR2, CXCR4, XCL1, XCL2, TNFRSF1B, TNF

Calcium-phosphate-dihydrate

hsa04062

Chemokine signaling pathway

2.66E-03

P51684, P25024, P25025, Q8NHW4, P07948, P19174, P62873, P63218, P50151, Q08828, P51828, Q13009, P14598, P42224, P31751, P49841

CCR6, CXCR1, CXCR2, CCL4L2, LYN, PLCG1, GNB1, GNG5, GNG10, ADCY1, ADCY7, TIAM1, NCF1, STAT1, AKT2, GSK3B

Calcium-phosphate-dihydrate

hsa04064

NF-kappa B signaling pathway

1.34E-05

P10415, Q13489, P51617, O00463, P01584, P01375, P29965, P19174, Q04759, Q16548, P06239, P63279, P24522, O75293, Q8NHW4, P09341, Q99731, Q9NQC7

BCL2, BIRC3, IRAK1, TRAF5, IL1B, TNF, CD40LG, PLCG1, PRKCQ, BCL2A1, LCK, UBE2I, GADD45A, GADD45B, CCL4L2, CXCL1, CCL19, CYLD

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP25	CALM3	Calmodulin-3	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP23	CALM1	Calmodulin-1	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP24	CALM2	Calmodulin-2	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP25	CALM3	Calmodulin-3	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP23	CALM1	Calmodulin-1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP24	CALM2	Calmodulin-2	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP25	CALM3	Calmodulin-3	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P25815	S100P	Protein S100-P	O00463	TRAF5	TNF receptor-associated factor 5	-0.832
P0DP24	CALM2	Calmodulin-2	P01584	IL1B	Interleukin-1 beta	0.72
P25815	S100P	Protein S100-P	P01584	IL1B	Interleukin-1 beta	0.719
P25815	S100P	Protein S100-P	P01375	TNF	Tumor necrosis factor	0.896
P0DP23	CALM1	Calmodulin-1	P29965	CD40LG	CD40 ligand	-0.721
P0DP24	CALM2	Calmodulin-2	P29965	CD40LG	CD40 ligand	-0.721
P0DP25	CALM3	Calmodulin-3	P29965	CD40LG	CD40 ligand	-0.721
P0DP23	CALM1	Calmodulin-1	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP24	CALM2	Calmodulin-2	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP25	CALM3	Calmodulin-3	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P25815	S100P	Protein S100-P	Q04759	PRKCQ	Protein kinase C theta type	-0.853
P25815	S100P	Protein S100-P	Q16548	BCL2A1	Bcl-2-related protein A1	0.784
P25815	S100P	Protein S100-P	P06239	LCK	Tyrosine-protein kinase Lck	-0.729
P25815	S100P	Protein S100-P	P63279	UBE2I	SUMO-conjugating enzyme UBC9	0.714
P25815	S100P	Protein S100-P	P24522	GADD45A	Growth arrest and DNA damage-inducible protein GADD45 alpha	0.733
P0DP23	CALM1	Calmodulin-1	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP24	CALM2	Calmodulin-2	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP25	CALM3	Calmodulin-3	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP23	CALM1	Calmodulin-1	Q8NHW4	CCL4L2	C-C motif chemokine 4-like	0.729
P0DP23	CALM1	Calmodulin-1	Q8NHW4	CCL4L2	C-C motif chemokine 4-like	0.729
P25815	S100P	Protein S100-P	P09341	CXCL1	Growth-regulated alpha protein	0.851
P25815	S100P	Protein S100-P	Q99731	CCL19	C-C motif chemokine 19	0.871
P0DP23	CALM1	Calmodulin-1	Q9NQC7	CYLD	Ubiquitin carboxyl-terminal hydrolase CYLD	0.883
P0DP24	CALM2	Calmodulin-2	Q9NQC7	CYLD	Ubiquitin carboxyl-terminal hydrolase CYLD	0.778

Calcium-phosphate-dihydrate

hsa04068

FoxO signaling pathway

4.30E-02

P30279, Q9NSB8, P84022, Q13485

CCND2, HOMER2, SMAD3, SMAD4

Calcium-phosphate-dihydrate

hsa04070

Phosphatidylinositol signaling system

5.66E-04

P19174, P0DP23, P23743, P48426, P27987, P17252

PLCG1, CALM1, DGKA, PIP4K2A, ITPKB, PRKCA

Calcium-phosphate-dihydrate

hsa04071

Sphingolipid signaling pathway

4.63E-03

P17252, P01375, Q13510, Q13362, Q16537, Q9BX95, Q16539, P10415, Q9UQC2, P01042

PRKCA, TNF, ASAH1, PPP2R5C, PPP2R5E, SGPP1, MAPK14, BCL2, GAB2, KNG1

Calcium-phosphate-dihydrate

hsa04072

Phospholipase D signaling pathway

2.03E-02

P31751, P19174, P17252, Q15438, Q08828, P51828, P23743, P00734

AKT2, PLCG1, PRKCA, PSCD1, ADCY1, ADCY7, DGKA, F2

Calcium-phosphate-dihydrate

hsa04080

Neuroactive ligand-receptor interaction

1.61E-02

P43657, Q01726, P21730, P14416, P35318

P2RY5, MC1R, C5AR1, DRD2, ADM

Calcium-phosphate-dihydrate

hsa04110

Cell cycle

2.40E-02

O60566, Q09472, P24522, P42773, P01106

BUB1B, EP300, GADD45A, CDKN2C, MYC

Calcium-phosphate-dihydrate

hsa04114

Oocyte meiosis

1.28E-03

Q9Y6D9, P51812, Q02750, Q9UJX2, Q14643, P16298, Q17RY0, P22694, Q16539, Q14683, Q13362, Q16537

MAD1L1, RPS6KA3, MAP2K1, CDC23, ITPR1, PPP3CB, CPEB4, PRKACB, MAPK14, SMC1A, PPP2R5C, PPP2R5E

Calcium-phosphate-dihydrate

hsa04140

Autophagy - animal

2.58E-02

P31751, Q7L523, Q96RR4, O75460, P10415, Q96GC9, Q8TEV9

AKT2, RRAGA, CAMKK2, ERN1, BCL2, TMEM49, SMCR8

Calcium-phosphate-dihydrate

hsa04141

Protein processing in endoplasmic reticulum

2.37E-03

P18848, P30101, Q15436, Q86TM6, P60604, Q99941, P11142, Q9H3Z4, Q8IXB1, P07900, P08238, Q9NR31, Q07065

ATF4, PDIA3, SEC23A, SYVN1, UBE2G2, CREBL1, HSPA8, DNAJC5, DNAJC10, HSP90AA1, HSP90AB1, SAR1A, CKAP4

Calcium-phosphate-dihydrate

hsa04144

Endocytosis

8.99E-03

P11142, Q9H444, O43633, O75351, Q9NZZ3, Q15438, Q14161, P14784, Q96QK1, Q9UMY4, Q9Y5X3, Q9UNH7

HSPA8, CHMP4B, CHMP2A, VPS4B, CHMP5, PSCD1, GIT2, IL2RB, VPS35, SNX12, SNX5, SNX6

Calcium-phosphate-dihydrate

hsa04145

Phagosome

1.34E-03

P60709, P63261, Q15075, Q15080, P14598, Q13509, Q13488, O60603, P01889, P10321

ACTB, ACTG1, EEA1, NCF4, NCF1, TUBB3, TCIRG1, TLR2, HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa04146

Peroxisome

7.06E-03

Q14032, P00441

BAAT, SOD1

Calcium-phosphate-dihydrate

hsa04150

mTOR signaling pathway

4.20E-02

Q02750, Q9NQL2, P51812

MAP2K1, RRAGD, RPS6KA3

Calcium-phosphate-dihydrate

hsa04151

PI3K-Akt signaling pathway

5.26E-05

P62753, P21860, O43521, P27348, P20827, O14944, P49767, Q13362, P07900, P08238, Q15831, P62873, P61952, P16144, Q16363, P22105, P48551, P14784, P23458, P01568, P15336, Q99941, P18848, P10415, P17252, Q16513, O00141, Q6ZUJ8

RPS6, ERBB3, BCL2L11, YWHAQ, EFNA1, EREG, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, STK11, GNB1, GNG11, ITGB4, LAMA4, TNXB, IFNAR2, IL2RB, JAK1, IFNA21, ATF2, CREBL1, ATF4, BCL2, PRKCA, PKN2, SGK, PIK3AP1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62753	RPS6	40S ribosomal protein S6	0.77
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P21860	ERBB3	Receptor tyrosine-protein kinase erbB-3	-0.753
P0DP24	CALM2	Calmodulin-2	O43521	BCL2L11	Bcl-2-like protein 11	0.75
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O43521	BCL2L11	Bcl-2-like protein 11	0.753
P0DP24	CALM2	Calmodulin-2	P27348	YWHAQ	14-3-3 protein theta	0.777
P0DP24	CALM2	Calmodulin-2	P20827	EFNA1	Ephrin-A1	-0.795
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O14944	EREG	Proepiregulin [Cleaved into: Epiregulin	-0.729
P0DP24	CALM2	Calmodulin-2	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP24	CALM2	Calmodulin-2	Q13362	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	0.765
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P07900	HSP90AA1	Heat shock protein HSP 90-alpha	0.708
P0DP24	CALM2	Calmodulin-2	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q15831	STK11	Serine/threonine-protein kinase STK11	0.744
P0DP24	CALM2	Calmodulin-2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.818
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61952	GNG11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	-0.716
P0DP24	CALM2	Calmodulin-2	P16144	ITGB4	Integrin beta-4	-0.725
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q16363	LAMA4	Laminin subunit alpha-4	0.755
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P22105	TNXB	Tenascin-X	0.752
P60660	MYL6	Myosin light polypeptide 6	P48551	IFNAR2	Interferon alpha/beta receptor 2	0.746
P0DP24	CALM2	Calmodulin-2	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.801
P0DP24	CALM2	Calmodulin-2	P23458	JAK1	Tyrosine-protein kinase JAK1	0.738
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852
P60660	MYL6	Myosin light polypeptide 6	P15336	ATF2	Cyclic AMP-dependent transcription factor ATF-2	0.729
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q99941	CREBL1	Cyclic AMP-dependent transcription factor ATF-6 beta	0.752
P0DP24	CALM2	Calmodulin-2	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.708
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P60660	MYL6	Myosin light polypeptide 6	Q16513	PKN2	Serine/threonine-protein kinase N2	-0.748
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O00141	SGK	Serine/threonine-protein kinase Sgk1	0.742
P0DP24	CALM2	Calmodulin-2	Q6ZUJ8	PIK3AP1	Phosphoinositide 3-kinase adapter protein 1	0.859

Calcium-phosphate-dihydrate

hsa04210

Apoptosis

6.18E-03

P07384, P60709, P63261

CAPN1, ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa04211

Longevity regulating pathway

4.68E-02

Q08828, Q02930, Q96RR4

ADCY1, CREB5, CAMKK2

Calcium-phosphate-dihydrate

hsa04217

Necroptosis

1.95E-10

P01568, P23458, Q13489, Q9NQC7, P42224, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, P10415, Q13557, Q9H444, O43633, Q9NZZ3, O75351, P45880

IFNA21, JAK1, BIRC3, CYLD, STAT1, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, BCL2, CAMK2D, CHMP4B, CHMP2A, CHMP5, VPS4B, VDAC2

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP25	CALM3	Calmodulin-3	P01568	IFNA21	Interferon alpha-21	-0.852
P13693	TPT1	Translationally-controlled tumor protein	P23458	JAK1	Tyrosine-protein kinase JAK1	0.847
P0DP23	CALM1	Calmodulin-1	P23458	JAK1	Tyrosine-protein kinase JAK1	0.822
P0DP24	CALM2	Calmodulin-2	P23458	JAK1	Tyrosine-protein kinase JAK1	0.738
P0DP23	CALM1	Calmodulin-1	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP24	CALM2	Calmodulin-2	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP25	CALM3	Calmodulin-3	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP23	CALM1	Calmodulin-1	Q9NQC7	CYLD	Ubiquitin carboxyl-terminal hydrolase CYLD	0.883
P0DP24	CALM2	Calmodulin-2	Q9NQC7	CYLD	Ubiquitin carboxyl-terminal hydrolase CYLD	0.778
P0DP23	CALM1	Calmodulin-1	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP24	CALM2	Calmodulin-2	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP25	CALM3	Calmodulin-3	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P07900	HSP90AA1	Heat shock protein HSP 90-alpha	0.708
P0DP23	CALM1	Calmodulin-1	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
P0DP24	CALM2	Calmodulin-2	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
P0DP25	CALM3	Calmodulin-3	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P15104	GLUL	Glutamine synthetase	0.791
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
P13693	TPT1	Translationally-controlled tumor protein	P01584	IL1B	Interleukin-1 beta	0.826
P0DP24	CALM2	Calmodulin-2	P01584	IL1B	Interleukin-1 beta	0.72
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P13693	TPT1	Translationally-controlled tumor protein	P0C0S5	H2AFZ	Histone H2A.Z	0.757
P0DP24	CALM2	Calmodulin-2	P0C0S5	H2AFZ	Histone H2A.Z	0.749
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P0C0S5	H2AFZ	Histone H2A.Z	0.761
P0DP23	CALM1	Calmodulin-1	Q6FI13	H2AC18; H2AC19	Histone H2A type 2-A	0.81
P0DP24	CALM2	Calmodulin-2	Q6FI13	H2AC18; H2AC19	Histone H2A type 2-A	0.81
P0DP25	CALM3	Calmodulin-3	Q6FI13	H2AC18; H2AC19	Histone H2A type 2-A	0.81
P0DP23	CALM1	Calmodulin-1	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP25	CALM3	Calmodulin-3	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P13693	TPT1	Translationally-controlled tumor protein	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.774
P0DP24	CALM2	Calmodulin-2	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.786
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.861
P13693	TPT1	Translationally-controlled tumor protein	Q9H444	CHMP4B	Charged multivesicular body protein 4b	0.752
P0DP23	CALM1	Calmodulin-1	Q9H444	CHMP4B	Charged multivesicular body protein 4b	0.73
P0DP24	CALM2	Calmodulin-2	Q9H444	CHMP4B	Charged multivesicular body protein 4b	0.713
P0DP23	CALM1	Calmodulin-1	O43633	CHMP2A	Charged multivesicular body protein 2a	0.842
P0DP24	CALM2	Calmodulin-2	O43633	CHMP2A	Charged multivesicular body protein 2a	0.842
P0DP25	CALM3	Calmodulin-3	O43633	CHMP2A	Charged multivesicular body protein 2a	0.842
P0DP23	CALM1	Calmodulin-1	Q9NZZ3	CHMP5	Charged multivesicular body protein 5	0.713
P0DP24	CALM2	Calmodulin-2	Q9NZZ3	CHMP5	Charged multivesicular body protein 5	0.763
P0DP23	CALM1	Calmodulin-1	O75351	VPS4B	Vacuolar protein sorting-associated protein 4B	0.784
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707

Calcium-phosphate-dihydrate

hsa04218

Cellular senescence

1.09E-03

P01106, P42338, P14921, O75293, P30304, P06493, P01889, P10321

MYC, PIK3CB, ETS1, GADD45B, CDC25A, CDK1, HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa04261

Adrenergic signaling in cardiomyocytes

4.43E-06

P09493, Q08828, P51828, P31751, P18848, Q13362, P0DP23, Q13557, P17252, P10415, P23634

TPM1, ADCY1, ADCY7, AKT2, ATF4, PPP2R5C, CALM1, CAMK2D, PRKCA, BCL2, ATP2B4

Calcium-phosphate-dihydrate

hsa04360

Axon guidance

8.44E-04

P61073, P16333, P20827, O95631, P17252, Q13557, P23528, P19174

CXCR4, NCK1, EFNA1, NTN1, PRKCA, CAMK2D, CFL1, PLCG1

Calcium-phosphate-dihydrate

hsa04370

VEGF signaling pathway

1.66E-03

P16298, Q05397, Q02750

PPP3CB, PTK2, MAP2K1

Calcium-phosphate-dihydrate

hsa04371

Apelin signaling pathway

1.70E-03

P62873, P31751, Q08828, P51828, Q13370, Q14344, Q13485, P84022, Q16566, P0DP23

GNB1, AKT2, ADCY1, ADCY7, PDE3B, GNA13, SMAD4, SMAD3, CAMK4, CALM1

Calcium-phosphate-dihydrate

hsa04380

Osteoclast differentiation

5.96E-03

Q9NQC7, Q9UQC2, P23458, P42224, P01584, Q15080, P14598

CYLD, GAB2, JAK1, STAT1, IL1B, NCF4, NCF1

Calcium-phosphate-dihydrate

hsa04390

Hippo signaling pathway

1.37E-03

P60709, P63261, Q13485, O15105, O43623

ACTB, ACTG1, SMAD4, SMAD7, SNAI2

Calcium-phosphate-dihydrate

hsa04510

Focal adhesion

6.39E-03

P16144, P08514, O75369, Q15746, P24844, Q15942, P17252, Q13489, P10415, P49767

ITGB4, ITGA2B, FLNB, MYLK, MYL9, ZYX, PRKCA, BIRC3, BCL2, VEGFC

Calcium-phosphate-dihydrate

hsa04512

ECM-receptor interaction

3.53E-02

P07359, P08514

GP1BA, ITGA2B

Calcium-phosphate-dihydrate

hsa04514

Cell adhesion molecules

9.26E-04

P16109, P13765, P01889, P10321, O00501

SELP, HLA-DOB, HLA-B, HLA-C, CLDN5

Calcium-phosphate-dihydrate

hsa04520

Adherens junction

1.91E-04

Q13485, Q09472, O43623, P60709, P63261, P12814

SMAD4, EP300, SNAI2, ACTB, ACTG1, ACTN1

Calcium-phosphate-dihydrate

hsa04530

Tight junction

2.26E-05

Q8TEU7, P60709, P63261, O00501, Q14247, P24844, P60660

RAPGEF6, ACTB, ACTG1, CLDN5, CTTN, MYL9, MYL6

Calcium-phosphate-dihydrate

hsa04540

Gap junction

4.08E-02

P17252, Q13509, P68371, Q08828, P51828

PRKCA, TUBB3, TUBB2C, ADCY1, ADCY7

Calcium-phosphate-dihydrate

hsa04610

Complement and coagulation cascades

2.77E-05

P25116, P09871, P0C0L4, P10909

F2R, C1S, C4A, CLU

Calcium-phosphate-dihydrate

hsa04611

Platelet activation

1.17E-05

P25116, P08514, Q14344, Q15746, P60709, P63261, P07359

F2R, ITGA2B, GNA13, MYLK, ACTB, ACTG1, GP1BA

Calcium-phosphate-dihydrate

hsa04612

Antigen processing and presentation

2.01E-05

P04233, P01889, P10321, Q06323

CD74, HLA-B, HLA-C, PSME1

Calcium-phosphate-dihydrate

hsa04613

Neutrophil extracellular trap formation

7.60E-04

P16109, O60603, P08246, Q9UM07, Q6FI13, P68431, Q15080, P49913, P08514, P07359

SELP, TLR2, ELA2, PADI4, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, CAMP, ITGA2B, GP1BA

Calcium-phosphate-dihydrate

hsa04620

Toll-like receptor signaling pathway

1.37E-03

P51617, P01568, P01584, P31751, P42224, Q8NHW4

IRAK1, IFNA21, IL1B, AKT2, STAT1, CCL4L2

Calcium-phosphate-dihydrate

hsa04621

NOD-like receptor signaling pathway

3.16E-02

P01584, P08238, P23458, P42224, P01568, Q9H3M7, Q13489, P43490, P10415

IL1B, HSP90AB1, JAK1, STAT1, IFNA21, TXNIP, BIRC3, PBEF1, BCL2

Calcium-phosphate-dihydrate

hsa04623

Cytosolic DNA-sensing pathway

3.53E-04

P01584, P01568, Q8NHW4

IL1B, IFNA21, CCL4L2

Calcium-phosphate-dihydrate

hsa04630

JAK-STAT signaling pathway

1.16E-02

P31751, P10415, P42224, P23458, P14784, P16871, Q13651, P01568

AKT2, BCL2, STAT1, JAK1, IL2RB, IL7R, IL10RA, IFNA21

Calcium-phosphate-dihydrate

hsa04640

Hematopoietic cell lineage

7.84E-06

P13612, P07359, P08514, P21926, P14778, P27930, P11215, P07766, P01730, P06127, P09564, P13765

ITGA4, GP1BA, ITGA2B, CD9, IL1R1, IL1R2, ITGAM, CD3E, CD4, CD5, CD7, HLA-DOB

Calcium-phosphate-dihydrate

hsa04650

Natural killer cell mediated cytotoxicity

2.52E-05

P16298, P50591, P01375, P06239, O60880, P20963, Q29983, P10321, P01889, Q02750, Q13241, P26718, O75015, P26717, P26715

PPP3CB, TNFSF10, TNF, LCK, SH2D1A, CD247, MICA, HLA-C, HLA-B, MAP2K1, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1

Calcium-phosphate-dihydrate

hsa04658

Th1 and Th2 cell differentiation

2.68E-06

P25963, Q04759, P07766, P20963, P19174, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P46531, Q9UM47, Q13761

NFKBIA, PRKCQ, CD3E, CD247, PLCG1, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, NOTCH1, NOTCH3, RUNX3

Calcium-phosphate-dihydrate

hsa04659

Th17 cell differentiation

7.07E-04

P19174, P01730, P06239, P14784, P14778, Q9UL17, P08238, P07766, P20963

PLCG1, CD4, LCK, IL2RB, IL1R1, TBX21, HSP90AB1, CD3E, CD247

Calcium-phosphate-dihydrate

hsa04660

T cell receptor signaling pathway

1.50E-03

P01375, Q04759, P42338, O95267, Q08881, P19174, Q9NQU5, P07766, P20963, P01730, P01732, Q13191, P06239

TNF, PRKCQ, PIK3CB, RASGRP1, ITK, PLCG1, PAK6, CD3E, CD247, CD4, CD8A, CBLB, LCK

Calcium-phosphate-dihydrate

hsa04662

B cell receptor signaling pathway

1.47E-06

P25963, P49841, P42338, P20023, P60033, P16298, P07948, P11912, P21854, Q8N149, Q02750

NFKBIA, GSK3B, PIK3CB, CR2, CD81, PPP3CB, LYN, CD79A, CD72, LILRA2, MAP2K1

Calcium-phosphate-dihydrate

hsa04664

Fc epsilon RI signaling pathway

2.36E-03

Q16539, P42338, P07948, P19174, P09917

MAPK14, PIK3CB, LYN, PLCG1, ALOX5

Calcium-phosphate-dihydrate

hsa04666

Fc gamma R-mediated phagocytosis

2.78E-02

P08575, P19174, P23528, Q9UQC2, P14598, P17252

PTPRC, PLCG1, CFL1, GAB2, NCF1, PRKCA

Calcium-phosphate-dihydrate

hsa04668

TNF signaling pathway

2.69E-02

P01375, O00463, P18848, P09341, P01584, P20749, P14780, P20333

TNF, TRAF5, ATF4, CXCL1, IL1B, BCL3, MMP9, TNFRSF1B

Calcium-phosphate-dihydrate

hsa04670

Leukocyte transendothelial migration

9.46E-03

P13612, P11215, P42338, P60709, P63261, P19174, Q15669, P12814

ITGA4, ITGAM, PIK3CB, ACTB, ACTG1, PLCG1, RHOH, ACTN1

Calcium-phosphate-dihydrate

hsa04713

Circadian entrainment

1.50E-06

O15399, P0DP23, Q13557, P17252, P62873, P61952, Q08828, P51828, P63092

GRIN2D, CALM1, CAMK2D, PRKCA, GNB1, GNG11, ADCY1, ADCY7, GNAS

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP24	CALM2	Calmodulin-2	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP25	CALM3	Calmodulin-3	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P0DP23	CALM1	Calmodulin-1	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P0DP23	CALM1	Calmodulin-1	1
P0DP25	CALM3	Calmodulin-3	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.786
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.861
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP25	CALM3	Calmodulin-3	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP23	CALM1	Calmodulin-1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP24	CALM2	Calmodulin-2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP25	CALM3	Calmodulin-3	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.818
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61952	GNG11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	-0.716
P0DP23	CALM1	Calmodulin-1	Q08828	ADCY1	Adenylate cyclase type 1	0.725
P0DP24	CALM2	Calmodulin-2	Q08828	ADCY1	Adenylate cyclase type 1	0.711
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q08828	ADCY1	Adenylate cyclase type 1	0.714
P0DP23	CALM1	Calmodulin-1	P51828	ADCY7	Adenylate cyclase type 7	0.719
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702

Calcium-phosphate-dihydrate

hsa04714

Thermogenesis

8.52E-06

P63092, P15336, Q08828, P60709, P63261, P62753, P13073, P12074, O15239, O95298, P36542, P05496

GNAS, ATF2, ADCY1, ACTB, ACTG1, RPS6, COX4I1, COX6A1, NDUFA1, NDUFC2, ATP5C1, ATP5G1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702
P60660	MYL6	Myosin light polypeptide 6	P15336	ATF2	Cyclic AMP-dependent transcription factor ATF-2	0.729
P13693	TPT1	Translationally-controlled tumor protein	Q08828	ADCY1	Adenylate cyclase type 1	0.88
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q08828	ADCY1	Adenylate cyclase type 1	0.714
P60660	MYL6	Myosin light polypeptide 6	P60709	ACTB	Actin, cytoplasmic 1	0.723
P60660	MYL6	Myosin light polypeptide 6	P63261	ACTG1	Actin, cytoplasmic 2	0.723
P13693	TPT1	Translationally-controlled tumor protein	P62753	RPS6	40S ribosomal protein S6	0.773
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62753	RPS6	40S ribosomal protein S6	0.77
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P60660	MYL6	Myosin light polypeptide 6	P36542	ATP5C1	ATP synthase subunit gamma, mitochondrial	-0.804
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779

Calcium-phosphate-dihydrate

hsa04720

Long-term potentiation

2.13E-04

P17252, Q13557, P16298, P0DP23, P51812, P18848, O15399, Q08828, Q02750

PRKCA, CAMK2D, PPP3CB, CALM1, RPS6KA3, ATF4, GRIN2D, ADCY1, MAP2K1

Calcium-phosphate-dihydrate

hsa04724

Glutamatergic synapse

3.09E-08

P48058, O15399, P43003, Q08828, P51828, P63092, P17252, P62873, P63218, P50151, P61952, P15104, Q9NSB8

GRIA4, GRIN2D, SLC1A3, ADCY1, ADCY7, GNAS, PRKCA, GNB1, GNG5, GNG10, GNG11, GLUL, HOMER2

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P09486	SPARC	SPARC	P48058	GRIA4	Glutamate receptor 4	-0.751
P24844	MYL9	Myosin regulatory light polypeptide 9	P48058	GRIA4	Glutamate receptor 4	-0.771
P0DP23	CALM1	Calmodulin-1	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	-0.764
P28676	GCA	Grancalcin	O15399	GRIN2D	Glutamate receptor ionotropic, NMDA 2D	0.732
P28676	GCA	Grancalcin	P43003	SLC1A3	Excitatory amino acid transporter 1	0.726
P80511	S100A12	Protein S100-A12	P43003	SLC1A3	Excitatory amino acid transporter 1	0.72
P0DP23	CALM1	Calmodulin-1	Q08828	ADCY1	Adenylate cyclase type 1	0.725
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q08828	ADCY1	Adenylate cyclase type 1	0.714
P0DP23	CALM1	Calmodulin-1	P51828	ADCY7	Adenylate cyclase type 7	0.719
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP23	CALM1	Calmodulin-1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.818
P28676	GCA	Grancalcin	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	0.913
P80511	S100A12	Protein S100-A12	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	0.777
P28676	GCA	Grancalcin	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	0.95
P80511	S100A12	Protein S100-A12	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	0.789
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61952	GNG11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	-0.716
P28676	GCA	Grancalcin	P15104	GLUL	Glutamine synthetase	0.925
P80511	S100A12	Protein S100-A12	P15104	GLUL	Glutamine synthetase	0.826
P24844	MYL9	Myosin regulatory light polypeptide 9	P15104	GLUL	Glutamine synthetase	-0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P15104	GLUL	Glutamine synthetase	0.791
P09486	SPARC	SPARC	Q9NSB8	HOMER2	Homer protein homolog 2	0.727

Calcium-phosphate-dihydrate

hsa04725

Cholinergic synapse

1.92E-05

Q08828, P51828, P17252, P62873, P61952, P18848, Q13557, P31751, P10415

ADCY1, ADCY7, PRKCA, GNB1, GNG11, ATF4, CAMK2D, AKT2, BCL2

Calcium-phosphate-dihydrate

hsa04727

GABAergic synapse

2.19E-03

Q08828, P51828, P62873, P61952, P15104, P46459, Q15111, P17252

ADCY1, ADCY7, GNB1, GNG11, GLUL, NSF, PLCL1, PRKCA

Calcium-phosphate-dihydrate

hsa04728

Dopaminergic synapse

3.47E-04

P63092, P14416, P62873, P63218, P50151, P61952, P49841, Q99941, P18848, Q16539, Q13557, O15516

GNAS, DRD2, GNB1, GNG5, GNG10, GNG11, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, CLOCK

Calcium-phosphate-dihydrate

hsa04740

Olfactory transduction

2.61E-02

P62873, Q13557, P0DP23

GNB1, CAMK2D, CALM1

Calcium-phosphate-dihydrate

hsa04744

Phototransduction

1.30E-05

P62873, P0DP23

GNB1, CALM1

Calcium-phosphate-dihydrate

hsa04750

Inflammatory mediator regulation of TRP channels

4.32E-05

P01584, Q08828, P51828, Q13557, P19174, P17252, P0DP23, P01042

IL1B, ADCY1, ADCY7, CAMK2D, PLCG1, PRKCA, CALM1, KNG1

Calcium-phosphate-dihydrate

hsa04810

Regulation of actin cytoskeleton

4.09E-03

P24844, Q15746, P08514, P25116

MYL9, MYLK, ITGA2B, F2R

Calcium-phosphate-dihydrate

hsa04911

Insulin secretion

2.19E-04

Q08828, P63092, P17252, Q99941, P18848, Q13557

ADCY1, GNAS, PRKCA, CREBL1, ATF4, CAMK2D

Calcium-phosphate-dihydrate

hsa04912

GnRH signaling pathway

2.85E-02

P17252, Q08828, P18848, Q13557, P0DP23

PRKCA, ADCY1, ATF4, CAMK2D, CALM1

Calcium-phosphate-dihydrate

hsa04914

Progesterone-mediated oocyte maturation

1.13E-03

Q17RY0, Q08828, P51828, P31751, Q13370, Q9UJX4, Q9Y6D9, P08238, P51812, Q02750

CPEB4, ADCY1, ADCY7, AKT2, PDE3B, ANAPC5, MAD1L1, HSP90AB1, RPS6KA3, MAP2K1

Calcium-phosphate-dihydrate

hsa04915

Estrogen signaling pathway

3.28E-03

P18848, Q08828, P51828, P31751, P08238, P11142, P0DP23, Q15788, P10415

ATF4, ADCY1, ADCY7, AKT2, HSP90AB1, HSPA8, CALM1, NCOA1, BCL2

Calcium-phosphate-dihydrate

hsa04918

Thyroid hormone synthesis

1.00E-02

P63092, Q08828, Q99941, P18848, P02768

GNAS, ADCY1, CREBL1, ATF4, ALB

Calcium-phosphate-dihydrate

hsa04919

Thyroid hormone signaling pathway

3.20E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa04921

Oxytocin signaling pathway

1.77E-03

P60660, P60709, P63261

MYL6, ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa04923

Regulation of lipolysis in adipocytes

2.12E-02

Q08828, P51828, Q13370, P31751

ADCY1, ADCY7, PDE3B, AKT2

Calcium-phosphate-dihydrate

hsa04925

Aldosterone synthesis and secretion

2.21E-06

Q99941, P18848, Q02930, Q08828, P51828, P0DP23, P63092, P17252, Q13557, P23634

CREBL1, ATF4, CREB5, ADCY1, ADCY7, CALM1, GNAS, PRKCA, CAMK2D, ATP2B4

Calcium-phosphate-dihydrate

hsa04926

Relaxin signaling pathway

6.64E-03

P62873, P61952, Q99941, P18848, P63092, Q08828

GNB1, GNG11, CREBL1, ATF4, GNAS, ADCY1

Calcium-phosphate-dihydrate

hsa04927

Cortisol synthesis and secretion

8.24E-03

Q99941, P18848, Q08828, P63092

CREBL1, ATF4, ADCY1, GNAS

Calcium-phosphate-dihydrate

hsa04932

Non-alcoholic fatty liver disease

2.12E-05

O43521, P18848, O75460, P01584, P13073, P12074, O15239, O95298

BCL2L11, ATF4, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2

Calcium-phosphate-dihydrate

hsa04933

AGE-RAGE signaling pathway in diabetic complications

2.04E-06

Q13485, P01584, P42224, P10415, P31751, P49767, P17252, P19174

SMAD4, IL1B, STAT1, BCL2, AKT2, VEGFC, PRKCA, PLCG1

Calcium-phosphate-dihydrate

hsa04934

Cushing syndrome

6.14E-03

Q99941, P18848, Q08828, P63092, Q13557

CREBL1, ATF4, ADCY1, GNAS, CAMK2D

Calcium-phosphate-dihydrate

hsa04935

Growth hormone synthesis, secretion and action

3.93E-02

P19174, Q08828, P51828, P17252, P31751, P42224

PLCG1, ADCY1, ADCY7, PRKCA, AKT2, STAT1

Calcium-phosphate-dihydrate

hsa04940

Type I diabetes mellitus

4.45E-03

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa04962

Vasopressin-regulated water reabsorption

1.65E-02

Q02930, P61020, P46459

CREB5, RAB5B, NSF

Calcium-phosphate-dihydrate

hsa04964

Proximal tubule bicarbonate reclamation

4.16E-03

P22748, P00918, P49448

CA4, CA2, GLUD2

Calcium-phosphate-dihydrate

hsa04966

Collecting duct acid secretion

4.26E-02

P00918

CA2

Calcium-phosphate-dihydrate

hsa04970

Salivary secretion

1.35E-03

Q08828, P51828, P23634, P17252, P0DP23

ADCY1, ADCY7, ATP2B4, PRKCA, CALM1

Calcium-phosphate-dihydrate

hsa04971

Gastric acid secretion

1.02E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa04972

Pancreatic secretion

1.92E-03

P23634, P17252, Q08828, P51828, P62491

ATP2B4, PRKCA, ADCY1, ADCY7, RAB11A

Calcium-phosphate-dihydrate

hsa04973

Carbohydrate digestion and absorption

1.77E-02

O43451, P42338

MGAM, PIK3CB

Calcium-phosphate-dihydrate

hsa05010

Alzheimer disease

5.60E-06

O15239, O95298, P05496, P13073, P12074, Q00535, O75460, P01584, O95197, P18848, Q71U36, P67870, P05141, P45880, P28070, P43686

NDUFA1, NDUFC2, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, IL1B, RTN3, ATF4, TUBA1A, CSNK2B, SLC25A5, VDAC2, PSMB4, PSMC4

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	Q00535	CDK5	Cyclin-dependent-like kinase 5	0.764
P13693	TPT1	Translationally-controlled tumor protein	O75460	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	0.777
P13693	TPT1	Translationally-controlled tumor protein	P01584	IL1B	Interleukin-1 beta	0.826
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P13693	TPT1	Translationally-controlled tumor protein	O95197	RTN3	Reticulon-3	0.734
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O95197	RTN3	Reticulon-3	0.71
P13693	TPT1	Translationally-controlled tumor protein	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.705
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P67870	CSNK2B	Casein kinase II subunit beta	0.788
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796

Calcium-phosphate-dihydrate

hsa05012

Parkinson disease

2.96E-06

O15239, O95298, P13073, P12074, P05496, P05141, P45880, P63092, O75460, P18848, P28070, P43686, Q13557, Q71U36

NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, SLC25A5, VDAC2, GNAS, ERN1, ATF4, PSMB4, PSMC4, CAMK2D, TUBA1A

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702
P13693	TPT1	Translationally-controlled tumor protein	O75460	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	0.777
P13693	TPT1	Translationally-controlled tumor protein	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.705
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796
P13693	TPT1	Translationally-controlled tumor protein	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.774
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.861
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7

Calcium-phosphate-dihydrate

hsa05014

Amyotrophic lateral sclerosis

2.31E-05

P01375, P10415, P20333, Q16539, O15239, Q16718, O95298, O14521, P13073, P12074, P36542, P05496, Q9NZJ5, O75460, P18848, Q71U36, P28070, P43686, Q8TEV9, Q13561, P51991, P09651, Q7Z3B4, P35658, P43243, P60709, P63261, Q09161, Q16629, Q9UBU9

TNF, BCL2, TNFRSF1B, MAPK14, NDUFA1, NDUFA5, NDUFC2, SDHD, COX4I1, COX6A1, ATP5C1, ATP5G1, EIF2AK3, ERN1, ATF4, TUBA1A, PSMB4, PSMC4, SMCR8, DCTN2, HNRPA3, HNRNPA1, NUP54, NUP214, MATR3, ACTB, ACTG1, NCBP1, SFRS7, NXF1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P31949	S100A11	Protein S100-A11	P01375	TNF	Tumor necrosis factor	0.826
P31949	S100A11	Protein S100-A11	P10415	BCL2	Apoptosis regulator Bcl-2	-0.745
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P20333	TNFRSF1B	Tumor necrosis factor receptor superfamily member 1B	0.797
P31949	S100A11	Protein S100-A11	Q16539	MAPK14	Mitogen-activated protein kinase 14	0.724
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P31949	S100A11	Protein S100-A11	Q16718	NDUFA5	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	-0.923
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P31949	S100A11	Protein S100-A11	O14521	SDHD	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	-0.757
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P60660	MYL6	Myosin light polypeptide 6	P36542	ATP5C1	ATP synthase subunit gamma, mitochondrial	-0.804
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P31949	S100A11	Protein S100-A11	Q9NZJ5	EIF2AK3	Eukaryotic translation initiation factor 2-alpha kinase 3	-0.727
P13693	TPT1	Translationally-controlled tumor protein	O75460	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	0.777
P13693	TPT1	Translationally-controlled tumor protein	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.705
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796
P13693	TPT1	Translationally-controlled tumor protein	Q8TEV9	SMCR8	Guanine nucleotide exchange protein SMCR8	0.718
P31949	S100A11	Protein S100-A11	Q13561	DCTN2	Dynactin subunit 2	0.798
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P51991	HNRPA3	Heterogeneous nuclear ribonucleoprotein A3	0.725
P31949	S100A11	Protein S100-A11	P09651	HNRNPA1	Heterogeneous nuclear ribonucleoprotein A1	-0.734
P31949	S100A11	Protein S100-A11	Q7Z3B4	NUP54	Nucleoporin p54	-0.889
P31949	S100A11	Protein S100-A11	P35658	NUP214	Nuclear pore complex protein Nup214	0.916
P31949	S100A11	Protein S100-A11	P43243	MATR3	Matrin-3	-0.797
P60660	MYL6	Myosin light polypeptide 6	P60709	ACTB	Actin, cytoplasmic 1	0.723
P60660	MYL6	Myosin light polypeptide 6	P63261	ACTG1	Actin, cytoplasmic 2	0.723
P31949	S100A11	Protein S100-A11	Q09161	NCBP1	Nuclear cap-binding protein subunit 1	-0.822
P31949	S100A11	Protein S100-A11	Q16629	SFRS7	Serine/arginine-rich splicing factor 7	-0.913
P13693	TPT1	Translationally-controlled tumor protein	Q9UBU9	NXF1	Nuclear RNA export factor 1	0.806
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q9UBU9	NXF1	Nuclear RNA export factor 1	0.708

Calcium-phosphate-dihydrate

hsa05016

Huntington disease

4.41E-05

O15239, O95298, P13073, P12074, P05496, P24928, P62487, P05141, P45880, O75460, Q71U36, P28070, P43686

NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, POLR2A, POLR2G, SLC25A5, VDAC2, ERN1, TUBA1A, PSMB4, PSMC4

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P13693	TPT1	Translationally-controlled tumor protein	P24928	POLR2A	DNA-directed RNA polymerase II subunit RPB1	0.805
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P24928	POLR2A	DNA-directed RNA polymerase II subunit RPB1	0.789
P13693	TPT1	Translationally-controlled tumor protein	P62487	POLR2G	DNA-directed RNA polymerase II subunit RPB7	0.889
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62487	POLR2G	DNA-directed RNA polymerase II subunit RPB7	0.83
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
P13693	TPT1	Translationally-controlled tumor protein	O75460	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	0.777
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796

Calcium-phosphate-dihydrate

hsa05017

Spinocerebellar ataxia

8.59E-04

P17252, Q92915, O75460, Q8TB72, O15399, P42338, P31751, P28070, P43686, O00232, P21796

PRKCA, FGF14, ERN1, PUM2, GRIN2D, PIK3CB, AKT2, PSMB4, PSMC4, PSMD12, VDAC1

Calcium-phosphate-dihydrate

hsa05020

Prion disease

9.42E-06

P01584, P46531, O15239, O95298, P05496, P13073, P12074, P18848, P05141, P45880, P28070, P43686, Q71U36, P67870, Q99941

IL1B, NOTCH1, NDUFA1, NDUFC2, ATP5G1, COX4I1, COX6A1, ATF4, SLC25A5, VDAC2, PSMB4, PSMC4, TUBA1A, CSNK2B, CREBL1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P13693	TPT1	Translationally-controlled tumor protein	P01584	IL1B	Interleukin-1 beta	0.826
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P13693	TPT1	Translationally-controlled tumor protein	P46531	NOTCH1	Neurogenic locus notch homolog protein 1	0.797
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P46531	NOTCH1	Neurogenic locus notch homolog protein 1	0.853
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.705
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P67870	CSNK2B	Casein kinase II subunit beta	0.788
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q99941	CREBL1	Cyclic AMP-dependent transcription factor ATF-6 beta	0.752

Calcium-phosphate-dihydrate

hsa05022

Pathways of neurodegeneration - multiple diseases

1.30E-05

Q71U36, P67870, O15239, O95298, P13073, P12074, P05496, Q8TEV9, O75460, P18848, P05141, P45880, P20333, Q00535, P01584, Q13557, P28070, P43686

TUBA1A, CSNK2B, NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, SMCR8, ERN1, ATF4, SLC25A5, VDAC2, TNFRSF1B, CDK5, IL1B, CAMK2D, PSMB4, PSMC4

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q71U36	TUBA1A	Tubulin alpha-1A chain	0.7
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P67870	CSNK2B	Casein kinase II subunit beta	0.788
P13693	TPT1	Translationally-controlled tumor protein	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.842
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	O15239	NDUFA1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	0.917
P13693	TPT1	Translationally-controlled tumor protein	O95298	NDUFC2	NADH dehydrogenase [ubiquinone] 1 subunit C2	0.714
P13693	TPT1	Translationally-controlled tumor protein	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P13073	COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	0.763
P13693	TPT1	Translationally-controlled tumor protein	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.879
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P12074	COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial	0.831
P13693	TPT1	Translationally-controlled tumor protein	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.791
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05496	ATP5G1	ATP synthase F(0) complex subunit C1, mitochondrial	0.779
P13693	TPT1	Translationally-controlled tumor protein	Q8TEV9	SMCR8	Guanine nucleotide exchange protein SMCR8	0.718
P13693	TPT1	Translationally-controlled tumor protein	O75460	ERN1	Serine/threonine-protein kinase/endoribonuclease IRE1	0.777
P13693	TPT1	Translationally-controlled tumor protein	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.705
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
P13693	TPT1	Translationally-controlled tumor protein	P05141	SLC25A5	ADP/ATP translocase 2	0.709
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05141	SLC25A5	ADP/ATP translocase 2	0.814
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P45880	VDAC2	Voltage-dependent anion-selective channel protein 2	0.707
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P20333	TNFRSF1B	Tumor necrosis factor receptor superfamily member 1B	0.797
P13693	TPT1	Translationally-controlled tumor protein	Q00535	CDK5	Cyclin-dependent-like kinase 5	0.764
P13693	TPT1	Translationally-controlled tumor protein	P01584	IL1B	Interleukin-1 beta	0.826
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P13693	TPT1	Translationally-controlled tumor protein	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.774
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.861
P13693	TPT1	Translationally-controlled tumor protein	P28070	PSMB4	Proteasome subunit beta type-4	0.783
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P28070	PSMB4	Proteasome subunit beta type-4	0.718
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P43686	PSMC4	26S proteasome regulatory subunit 6B	0.796

Calcium-phosphate-dihydrate

hsa05031

Amphetamine addiction

1.40E-03

O15399, P0DP23, Q13557, P63092, Q99941, P18848, P17252

GRIN2D, CALM1, CAMK2D, GNAS, CREBL1, ATF4, PRKCA

Calcium-phosphate-dihydrate

hsa05032

Morphine addiction

2.21E-03

Q08828, P51828, P62873, P61952, Q13370, P63092, P17252

ADCY1, ADCY7, GNB1, GNG11, PDE3B, GNAS, PRKCA

Calcium-phosphate-dihydrate

hsa05034

Alcoholism

4.04E-04

P63092, Q99941, P18848, Q02930, P0DP23, Q96RR4, P62873, P61952, P0C0S5, Q9BTM1

GNAS, CREBL1, ATF4, CREB5, CALM1, CAMKK2, GNB1, GNG11, H2AFZ, H2AFJ

Calcium-phosphate-dihydrate

hsa05100

Bacterial invasion of epithelial cells

1.02E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05110

Vibrio cholerae infection

3.95E-03

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05120

Epithelial cell signaling in Helicobacter pylori infection

8.53E-03

Q16539, P25024, P25025, P07948

MAPK14, CXCR1, CXCR2, LYN

Calcium-phosphate-dihydrate

hsa05130

Pathogenic Escherichia coli infection

1.01E-03

Q71U36, Q14247, O00501, P68371, P25116, Q14344

TUBA1A, CTTN, CLDN5, TUBB2C, F2R, GNA13

Calcium-phosphate-dihydrate

hsa05131

Shigellosis

1.91E-02

P60709, P63261, P07384

ACTB, ACTG1, CAPN1

Calcium-phosphate-dihydrate

hsa05132

Salmonella infection

3.99E-04

P51617, P01584, P08238, Q96RF0, Q13489, P10415, P08575, O75369, Q13561, Q13509, P68371, P49754, Q9NP90

IRAK1, IL1B, HSP90AB1, SNAG1, BIRC3, BCL2, PTPRC, FLNB, DCTN2, TUBB3, TUBB2C, VPS41, RAB9B

Calcium-phosphate-dihydrate

hsa05133

Pertussis

4.55E-06

P0DP23, P01584, P23528, P09871, P0C0L4, P51617, Q02556

CALM1, IL1B, CFL1, C1S, C4A, IRAK1, IRF8

Calcium-phosphate-dihydrate

hsa05135

Yersinia infection

2.31E-04

P60709, P63261, Q05397, Q16513, P51812, Q02750, Q96JJ3

ACTB, ACTG1, PTK2, PKN2, RPS6KA3, MAP2K1, ELMO2

Calcium-phosphate-dihydrate

hsa05140

Leishmaniasis

2.58E-02

P14598, O60603, P25963, P29350, Q15080

NCF1, TLR2, NFKBIA, PTPN6, NCF4

Calcium-phosphate-dihydrate

hsa05143

African trypanosomiasis

7.67E-05

Q16363, P01584, P69905, P68871, P17252, P01042

LAMA4, IL1B, HBA2, HBB, PRKCA, KNG1

Calcium-phosphate-dihydrate

hsa05144

Malaria

2.29E-02

P60033, P01375, P35443, P01584, P26718

CD81, TNF, THBS4, IL1B, KLRK1

Calcium-phosphate-dihydrate

hsa05145

Toxoplasmosis

5.28E-05

P51617, P10415, Q13489, P23458, P42224, P31751, P11142, P29965, Q13651

IRAK1, BCL2, BIRC3, JAK1, STAT1, AKT2, HSPA8, CD40LG, IL10RA

Calcium-phosphate-dihydrate

hsa05146

Amoebiasis

3.72E-04

P01584, Q16363, Q13751, P09341, P14778, P27930, P01375, P42338, P11215, P05089, P22694, P12814, P08311

IL1B, LAMA4, LAMB3, CXCL1, IL1R1, IL1R2, TNF, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSG

Calcium-phosphate-dihydrate

hsa05150

Staphylococcus aureus infection

1.11E-04

P09871, P0C0L4, P13765, P13646, P16109

C1S, C4A, HLA-DOB, KRT13, SELP

Calcium-phosphate-dihydrate

hsa05152

Tuberculosis

4.22E-02

Q13488, O60603, P49913, Q9UDY8

TCIRG1, TLR2, CAMP, MALT1

Calcium-phosphate-dihydrate

hsa05161

Hepatitis B

1.31E-04

P17252, P18848, P23458, Q13485, P31751, P10415, P27348, P01568, P42224, P51617

PRKCA, ATF4, JAK1, SMAD4, AKT2, BCL2, YWHAQ, IFNA21, STAT1, IRAK1

Calcium-phosphate-dihydrate

hsa05162

Measles

1.74E-04

P51617, P01568, P23458, P42224, P14784, P31751, P11142, P01584, Q9NP90, P10415

IRAK1, IFNA21, JAK1, STAT1, IL2RB, AKT2, HSPA8, IL1B, RAB9B, BCL2

Calcium-phosphate-dihydrate

hsa05163

Human cytomegalovirus infection

2.28E-05

P31751, P62873, P63218, P50151, P61952, P0DP23, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, P61073, P17252, Q13651, P25025, Q16539, Q99941, P18848, P63092, P61769, P01568

AKT2, GNB1, GNG5, GNG10, GNG11, CALM1, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, CXCR4, PRKCA, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, GNAS, B2M, IFNA21

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P31751	AKT2	RAC-beta serine/threonine-protein kinase	0.761
P0DP23	CALM1	Calmodulin-1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP24	CALM2	Calmodulin-2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.818
P80511	S100A12	Protein S100-A12	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	0.777
P80511	S100A12	Protein S100-A12	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	0.789
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61952	GNG11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	-0.716
P0DP23	CALM1	Calmodulin-1	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P0DP23	CALM1	Calmodulin-1	1
P80511	S100A12	Protein S100-A12	Q14344	GNA13	Guanine nucleotide-binding protein subunit alpha-13	0.723
P0DP23	CALM1	Calmodulin-1	Q8NHW4	CCL4L2	C-C motif chemokine 4-like	0.729
P0DP23	CALM1	Calmodulin-1	Q8NHW4	CCL4L2	C-C motif chemokine 4-like	0.729
P0DP23	CALM1	Calmodulin-1	Q08828	ADCY1	Adenylate cyclase type 1	0.725
P0DP24	CALM2	Calmodulin-2	Q08828	ADCY1	Adenylate cyclase type 1	0.711
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q08828	ADCY1	Adenylate cyclase type 1	0.714
P0DP23	CALM1	Calmodulin-1	P51828	ADCY7	Adenylate cyclase type 7	0.719
P0DP23	CALM1	Calmodulin-1	P23458	JAK1	Tyrosine-protein kinase JAK1	0.822
P0DP24	CALM2	Calmodulin-2	P23458	JAK1	Tyrosine-protein kinase JAK1	0.738
P80511	S100A12	Protein S100-A12	P49841	GSK3B	Glycogen synthase kinase-3 beta	0.861
P80511	S100A12	Protein S100-A12	P14778	IL1R1	Interleukin-1 receptor type 1	0.811
P0DP24	CALM2	Calmodulin-2	P01584	IL1B	Interleukin-1 beta	0.72
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P0DP24	CALM2	Calmodulin-2	P61073	CXCR4	C-X-C chemokine receptor type 4	0.759
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61073	CXCR4	C-X-C chemokine receptor type 4	0.77
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP23	CALM1	Calmodulin-1	Q13651	IL10RA	Interleukin-10 receptor subunit alpha	0.701
P80511	S100A12	Protein S100-A12	P25025	CXCR2	C-X-C chemokine receptor type 2	0.779
P80511	S100A12	Protein S100-A12	Q16539	MAPK14	Mitogen-activated protein kinase 14	0.724
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	Q99941	CREBL1	Cyclic AMP-dependent transcription factor ATF-6 beta	0.752
P0DP24	CALM2	Calmodulin-2	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.708
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P18848	ATF4	Cyclic AMP-dependent transcription factor ATF-4	0.819
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63092	GNAS	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	0.702
P0DP24	CALM2	Calmodulin-2	P61769	B2M	Beta-2-microglobulin	0.787
P0DP23	CALM1	Calmodulin-1	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852

Calcium-phosphate-dihydrate

hsa05164

Influenza A

7.10E-03

P48551, P60709, P63261

IFNAR2, ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05165

Human papillomavirus infection

5.90E-03

P01889, P10321, O14745

HLA-B, HLA-C, SLC9A3R1

Calcium-phosphate-dihydrate

hsa05166

Human T-cell leukemia virus 1 infection

3.54E-02

P14784, P01106, P25963, P07766, P42338, P14921, P42773, P01730

IL2RB, MYC, NFKBIA, CD3E, PIK3CB, ETS1, CDKN2C, CD4

Calcium-phosphate-dihydrate

hsa05167

Kaposi sarcoma-associated herpesvirus infection

1.22E-03

P01889, P10321, Q29983

HLA-B, HLA-C, MICA

Calcium-phosphate-dihydrate

hsa05168

Herpes simplex virus 1 infection

2.41E-06

P01568, P01584, Q9UBU9, P23458, P42224, Q07955, Q01130, Q13243, P04233, Q13489, P51617, P01889, P10321, P61769, P31751, Q13398, Q6P280, Q03923, Q9UDV6, P10415, Q14232

IFNA21, IL1B, NXF1, JAK1, STAT1, SFRS1, SFRS2, SFRS5, CD74, BIRC3, IRAK1, HLA-B, HLA-C, B2M, AKT2, ZNF211, ZNF529, ZNF85, ZNF212, BCL2, EIF2B1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP25	CALM3	Calmodulin-3	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01584	IL1B	Interleukin-1 beta	0.72
P0DP23	CALM1	Calmodulin-1	Q9UBU9	NXF1	Nuclear RNA export factor 1	0.743
P0DP24	CALM2	Calmodulin-2	Q9UBU9	NXF1	Nuclear RNA export factor 1	0.772
P0DP23	CALM1	Calmodulin-1	P23458	JAK1	Tyrosine-protein kinase JAK1	0.822
P0DP24	CALM2	Calmodulin-2	P23458	JAK1	Tyrosine-protein kinase JAK1	0.738
P0DP23	CALM1	Calmodulin-1	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP24	CALM2	Calmodulin-2	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP25	CALM3	Calmodulin-3	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP23	CALM1	Calmodulin-1	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P0DP24	CALM2	Calmodulin-2	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P0DP25	CALM3	Calmodulin-3	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.914
P0DP23	CALM1	Calmodulin-1	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P0DP24	CALM2	Calmodulin-2	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P0DP25	CALM3	Calmodulin-3	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.841
P0DP23	CALM1	Calmodulin-1	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P0DP24	CALM2	Calmodulin-2	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P0DP25	CALM3	Calmodulin-3	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.784
P60903	S100A10	Protein S100-A10	P04233	CD74	HLA class II histocompatibility antigen gamma chain	0.812
P0DP23	CALM1	Calmodulin-1	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP24	CALM2	Calmodulin-2	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP25	CALM3	Calmodulin-3	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP23	CALM1	Calmodulin-1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP24	CALM2	Calmodulin-2	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP25	CALM3	Calmodulin-3	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P60903	S100A10	Protein S100-A10	P01889	HLA-B	HLA class I histocompatibility antigen, B alpha chain	0.757
P60903	S100A10	Protein S100-A10	P10321	HLA-C	HLA class I histocompatibility antigen, C alpha chain	0.757
P0DP24	CALM2	Calmodulin-2	P61769	B2M	Beta-2-microglobulin	0.787
P0DP23	CALM1	Calmodulin-1	P31751	AKT2	RAC-beta serine/threonine-protein kinase	0.761
P0DP23	CALM1	Calmodulin-1	Q13398	ZNF211	Zinc finger protein 211	0.898
P0DP24	CALM2	Calmodulin-2	Q13398	ZNF211	Zinc finger protein 211	0.898
P0DP25	CALM3	Calmodulin-3	Q13398	ZNF211	Zinc finger protein 211	0.898
P0DP23	CALM1	Calmodulin-1	Q6P280	ZNF529	Zinc finger protein 529	0.767
P0DP23	CALM1	Calmodulin-1	Q03923	ZNF85	Zinc finger protein 85	-0.818
P0DP24	CALM2	Calmodulin-2	Q03923	ZNF85	Zinc finger protein 85	-0.818
P0DP25	CALM3	Calmodulin-3	Q03923	ZNF85	Zinc finger protein 85	-0.818
P0DP23	CALM1	Calmodulin-1	Q9UDV6	ZNF212	Zinc finger protein 212	0.759
P0DP24	CALM2	Calmodulin-2	Q9UDV6	ZNF212	Zinc finger protein 212	0.759
P0DP25	CALM3	Calmodulin-3	Q9UDV6	ZNF212	Zinc finger protein 212	0.759
P0DP23	CALM1	Calmodulin-1	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP25	CALM3	Calmodulin-3	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP23	CALM1	Calmodulin-1	Q14232	EIF2B1	Translation initiation factor eIF-2B subunit alpha	0.797

Calcium-phosphate-dihydrate

hsa05169

Epstein-Barr virus infection

2.87E-02

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa05170

Human immunodeficiency virus 1 infection

8.89E-07

P31751, Q02750, P01889, P10321, P62873, P62879, P16298, P0DP23, P61073, Q05397, P17252, P61769, P01568, P51617, P19174, P23528, P10415, Q9Y6Q5

AKT2, MAP2K1, HLA-B, HLA-C, GNB1, GNB2, PPP3CB, CALM1, CXCR4, PTK2, PRKCA, B2M, IFNA21, IRAK1, PLCG1, CFL1, BCL2, AP1M2

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P31751	AKT2	RAC-beta serine/threonine-protein kinase	0.761
Q99653	CHP	Calcineurin B homologous protein 1	Q02750	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1	0.864
P60903	S100A10	Protein S100-A10	P01889	HLA-B	HLA class I histocompatibility antigen, B alpha chain	0.757
P60903	S100A10	Protein S100-A10	P10321	HLA-C	HLA class I histocompatibility antigen, C alpha chain	0.757
P0DP23	CALM1	Calmodulin-1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP24	CALM2	Calmodulin-2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP25	CALM3	Calmodulin-3	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
Q99653	CHP	Calcineurin B homologous protein 1	P62879	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.854
Q99653	CHP	Calcineurin B homologous protein 1	P16298	PPP3CB	Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	0.772
P0DP23	CALM1	Calmodulin-1	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P0DP23	CALM1	Calmodulin-1	1
P0DP25	CALM3	Calmodulin-3	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P61073	CXCR4	C-X-C chemokine receptor type 4	0.759
Q99653	CHP	Calcineurin B homologous protein 1	Q05397	PTK2	Focal adhesion kinase 1	0.787
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP25	CALM3	Calmodulin-3	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P61769	B2M	Beta-2-microglobulin	0.787
P0DP23	CALM1	Calmodulin-1	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP25	CALM3	Calmodulin-3	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP23	CALM1	Calmodulin-1	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP24	CALM2	Calmodulin-2	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP25	CALM3	Calmodulin-3	P51617	IRAK1	Interleukin-1 receptor-associated kinase 1	-0.703
P0DP23	CALM1	Calmodulin-1	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP24	CALM2	Calmodulin-2	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP25	CALM3	Calmodulin-3	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP23	CALM1	Calmodulin-1	P23528	CFL1	Cofilin-1	-0.832
P0DP24	CALM2	Calmodulin-2	P23528	CFL1	Cofilin-1	-0.832
P0DP25	CALM3	Calmodulin-3	P23528	CFL1	Cofilin-1	-0.832
P0DP23	CALM1	Calmodulin-1	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP25	CALM3	Calmodulin-3	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP23	CALM1	Calmodulin-1	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	0.742
P0DP24	CALM2	Calmodulin-2	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	0.742
P0DP25	CALM3	Calmodulin-3	Q9Y6Q5	AP1M2	AP-1 complex subunit mu-2	0.742

Calcium-phosphate-dihydrate

hsa05171

Coronavirus disease - COVID-19

4.25E-05

P01375, P23458, P01584, P23396, P62753, P25398, P39019, P62266, P42677, P62906, P36578, Q02878, P62917, P32969, Q07020, P62888, P61927, P61513, P63173, P05386, P62829, P21730

TNF, JAK1, IL1B, RPS3, RPS6, RPS12, RPS19, RPS23, RPS27, RPL10A, RPL4, RPL6, RPL8, RPL9, RPL18, RPL30, RPL37, RPL37A, RPL38, RPLP1, RPL23, C5AR1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P25815	S100P	Protein S100-P	P01375	TNF	Tumor necrosis factor	0.896
P13693	TPT1	Translationally-controlled tumor protein	P23458	JAK1	Tyrosine-protein kinase JAK1	0.847
P13693	TPT1	Translationally-controlled tumor protein	P01584	IL1B	Interleukin-1 beta	0.826
P25815	S100P	Protein S100-P	P01584	IL1B	Interleukin-1 beta	0.719
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P01584	IL1B	Interleukin-1 beta	0.79
P25815	S100P	Protein S100-P	P23396	RPS3	40S ribosomal protein S3	0.815
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P23396	RPS3	40S ribosomal protein S3	0.758
P13693	TPT1	Translationally-controlled tumor protein	P62753	RPS6	40S ribosomal protein S6	0.773
P25815	S100P	Protein S100-P	P62753	RPS6	40S ribosomal protein S6	0.799
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62753	RPS6	40S ribosomal protein S6	0.77
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P25398	RPS12	40S ribosomal protein S12	0.724
P13693	TPT1	Translationally-controlled tumor protein	P39019	RPS19	40S ribosomal protein S19	0.71
P25815	S100P	Protein S100-P	P39019	RPS19	40S ribosomal protein S19	0.79
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P39019	RPS19	40S ribosomal protein S19	0.791
P13693	TPT1	Translationally-controlled tumor protein	P62266	RPS23	40S ribosomal protein S23	0.801
P25815	S100P	Protein S100-P	P42677	RPS27	40S ribosomal protein S27	0.724
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P42677	RPS27	40S ribosomal protein S27	0.727
P13693	TPT1	Translationally-controlled tumor protein	P62906	RPL10A	60S ribosomal protein L10a	0.727
P25815	S100P	Protein S100-P	P62906	RPL10A	60S ribosomal protein L10a	0.754
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62906	RPL10A	60S ribosomal protein L10a	0.737
P25815	S100P	Protein S100-P	P36578	RPL4	60S ribosomal protein L4	0.84
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P36578	RPL4	60S ribosomal protein L4	0.749
P25815	S100P	Protein S100-P	Q02878	RPL6	60S ribosomal protein L6	0.738
P25815	S100P	Protein S100-P	P62917	RPL8	60S ribosomal protein L8	0.817
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P32969	RPL9	60S ribosomal protein L9	0.814
P25815	S100P	Protein S100-P	Q07020	RPL18	60S ribosomal protein L18	0.764
P13693	TPT1	Translationally-controlled tumor protein	P62888	RPL30	60S ribosomal protein L30	0.721
P13693	TPT1	Translationally-controlled tumor protein	P61927	RPL37	60S ribosomal protein L37	0.81
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61927	RPL37	60S ribosomal protein L37	0.772
P13693	TPT1	Translationally-controlled tumor protein	P61513	RPL37A	60S ribosomal protein L37a	0.846
P25815	S100P	Protein S100-P	P61513	RPL37A	60S ribosomal protein L37a	0.818
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P61513	RPL37A	60S ribosomal protein L37a	0.83
P25815	S100P	Protein S100-P	P63173	RPL38	60S ribosomal protein L38	0.79
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P63173	RPL38	60S ribosomal protein L38	0.756
P25815	S100P	Protein S100-P	P05386	RPLP1	60S acidic ribosomal protein P1	0.921
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P05386	RPLP1	60S acidic ribosomal protein P1	0.768
P13693	TPT1	Translationally-controlled tumor protein	P62829	RPL23	60S ribosomal protein L23	0.731
Q8N2S1	LTBP4	Latent-transforming growth factor beta-binding protein 4	P62829	RPL23	60S ribosomal protein L23	0.72
P25815	S100P	Protein S100-P	P21730	C5AR1	C5a anaphylatoxin chemotactic receptor 1	0.84

Calcium-phosphate-dihydrate

hsa05200

Pathways in cancer

4.30E-09

P23458, P08238, P42224, P19174, Q15311, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P31751, Q08828, P51828, P62873, P61073, P78417, O75293, Q15788, P0DP23, Q13557, O43521, P01568, P14784, P16871, P00734, P01042

JAK1, HSP90AB1, STAT1, PLCG1, RALBP1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, AKT2, ADCY1, ADCY7, GNB1, CXCR4, GSTO1, GADD45B, NCOA1, CALM1, CAMK2D, BCL2L11, IFNA21, IL2RB, IL7R, F2, KNG1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P0DP23	CALM1	Calmodulin-1	P23458	JAK1	Tyrosine-protein kinase JAK1	0.822
P0DP24	CALM2	Calmodulin-2	P23458	JAK1	Tyrosine-protein kinase JAK1	0.738
P0DP23	CALM1	Calmodulin-1	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
P0DP24	CALM2	Calmodulin-2	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
P0DP25	CALM3	Calmodulin-3	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.775
P0DP23	CALM1	Calmodulin-1	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP24	CALM2	Calmodulin-2	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP25	CALM3	Calmodulin-3	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.775
P0DP23	CALM1	Calmodulin-1	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP24	CALM2	Calmodulin-2	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP25	CALM3	Calmodulin-3	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.744
P0DP23	CALM1	Calmodulin-1	Q15311	RALBP1	RalA-binding protein 1	0.858
P0DP23	CALM1	Calmodulin-1	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP24	CALM2	Calmodulin-2	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP25	CALM3	Calmodulin-3	P17252	PRKCA	Protein kinase C alpha type	-0.776
P0DP23	CALM1	Calmodulin-1	P43246	MSH2	DNA mismatch repair protein Msh2	0.944
P0DP24	CALM2	Calmodulin-2	P43246	MSH2	DNA mismatch repair protein Msh2	0.944
P0DP25	CALM3	Calmodulin-3	P43246	MSH2	DNA mismatch repair protein Msh2	0.944
P0DP23	CALM1	Calmodulin-1	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	0.777
P0DP24	CALM2	Calmodulin-2	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	0.777
P0DP25	CALM3	Calmodulin-3	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	0.777
P0DP23	CALM1	Calmodulin-1	P14923	JUP	Junction plakoglobin	-0.852
P0DP24	CALM2	Calmodulin-2	P14923	JUP	Junction plakoglobin	-0.852
P0DP25	CALM3	Calmodulin-3	P14923	JUP	Junction plakoglobin	-0.852
P0DP23	CALM1	Calmodulin-1	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP24	CALM2	Calmodulin-2	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP25	CALM3	Calmodulin-3	P10415	BCL2	Apoptosis regulator Bcl-2	-0.772
P0DP23	CALM1	Calmodulin-1	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP24	CALM2	Calmodulin-2	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP25	CALM3	Calmodulin-3	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	-0.8
P0DP23	CALM1	Calmodulin-1	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP24	CALM2	Calmodulin-2	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP25	CALM3	Calmodulin-3	P49767	VEGFC	Vascular endothelial growth factor C	-0.84
P0DP23	CALM1	Calmodulin-1	P31751	AKT2	RAC-beta serine/threonine-protein kinase	0.761
P0DP23	CALM1	Calmodulin-1	Q08828	ADCY1	Adenylate cyclase type 1	0.725
P0DP24	CALM2	Calmodulin-2	Q08828	ADCY1	Adenylate cyclase type 1	0.711
P0DP23	CALM1	Calmodulin-1	P51828	ADCY7	Adenylate cyclase type 7	0.719
P0DP23	CALM1	Calmodulin-1	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP24	CALM2	Calmodulin-2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP25	CALM3	Calmodulin-3	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.853
P0DP24	CALM2	Calmodulin-2	P61073	CXCR4	C-X-C chemokine receptor type 4	0.759
P0DP23	CALM1	Calmodulin-1	P78417	GSTO1	Glutathione S-transferase omega-1	-0.804
P0DP24	CALM2	Calmodulin-2	P78417	GSTO1	Glutathione S-transferase omega-1	-0.804
P0DP25	CALM3	Calmodulin-3	P78417	GSTO1	Glutathione S-transferase omega-1	-0.804
P0DP23	CALM1	Calmodulin-1	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP24	CALM2	Calmodulin-2	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP25	CALM3	Calmodulin-3	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.853
P0DP24	CALM2	Calmodulin-2	Q15788	NCOA1	Nuclear receptor coactivator 1	0.731
P0DP23	CALM1	Calmodulin-1	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	P0DP23	CALM1	Calmodulin-1	1
P0DP25	CALM3	Calmodulin-3	P0DP23	CALM1	Calmodulin-1	1
P0DP24	CALM2	Calmodulin-2	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.786
P0DP24	CALM2	Calmodulin-2	O43521	BCL2L11	Bcl-2-like protein 11	0.75
P0DP23	CALM1	Calmodulin-1	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP24	CALM2	Calmodulin-2	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP25	CALM3	Calmodulin-3	P01568	IFNA21	Interferon alpha-21	-0.852
P0DP23	CALM1	Calmodulin-1	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.801
P0DP24	CALM2	Calmodulin-2	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.801
P0DP25	CALM3	Calmodulin-3	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.801
P0DP23	CALM1	Calmodulin-1	P16871	IL7R	Interleukin-7 receptor subunit alpha	0.718
P0DP23	CALM1	Calmodulin-1	P00734	F2	Prothrombin	-0.738
P0DP23	CALM1	Calmodulin-1	P01042	KNG1	Kininogen-1	-0.71
P0DP24	CALM2	Calmodulin-2	P01042	KNG1	Kininogen-1	-0.71
P0DP25	CALM3	Calmodulin-3	P01042	KNG1	Kininogen-1	-0.71

Calcium-phosphate-dihydrate

hsa05202

Transcriptional misregulation in cancer

4.88E-02

P01106, P35226, O60583, P04141, P59665, P59666, P42773, O75293

MYC, BMI1, CCNT2, CSF2, DEFA1; DEFA1B, DEFA3, CDKN2C, GADD45B

Calcium-phosphate-dihydrate

hsa05203

Viral carcinogenesis

1.99E-02

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa05204

Chemical carcinogenesis

3.70E-03

P00325, P78417, P33260

ADH1B, GSTO1, CYP2C18

Calcium-phosphate-dihydrate

hsa05206

MicroRNAs in cancer

6.16E-03

P15311, P01106, P26358, Q9UM47, P35226, Q96EB6, P63279, P19174

VIL2, MYC, DNMT1, NOTCH3, BMI1, SIRT1, UBE2I, PLCG1

Calcium-phosphate-dihydrate

hsa05210

Colorectal cancer

4.67E-02

P42338, O15392, P01106, O75293

PIK3CB, BIRC5, MYC, GADD45B

Calcium-phosphate-dihydrate

hsa05212

Pancreatic cancer

5.55E-03

P31751, Q15311, P23458, P42224, Q13485, O75293

AKT2, RALBP1, JAK1, STAT1, SMAD4, GADD45B

Calcium-phosphate-dihydrate

hsa05213

Endometrial cancer

8.14E-04

P40692, P01106, P42338, P24522, O75293

MLH1, MYC, PIK3CB, GADD45A, GADD45B

Calcium-phosphate-dihydrate

hsa05214

Glioma

1.87E-05

P0DP23, Q13557, P17252, P31751, P19174, O75293

CALM1, CAMK2D, PRKCA, AKT2, PLCG1, GADD45B

Calcium-phosphate-dihydrate

hsa05216

Thyroid cancer

3.48E-02

P01106, P24522

MYC, GADD45A

Calcium-phosphate-dihydrate

hsa05220

Chronic myeloid leukemia

3.04E-02

P01106, P25963, P42338, O75293

MYC, NFKBIA, PIK3CB, GADD45B

Calcium-phosphate-dihydrate

hsa05222

Small cell lung cancer

7.53E-03

P01106, P42338, Q13751, P25963, O75293

MYC, PIK3CB, LAMB3, NFKBIA, GADD45B

Calcium-phosphate-dihydrate

hsa05225

Hepatocellular carcinoma

4.07E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

2.26E-03

P25963, P42338, P19174, P07766, P20963, P06239, P01730

NFKBIA, PIK3CB, PLCG1, CD3E, CD247, LCK, CD4

Calcium-phosphate-dihydrate

hsa05320

Autoimmune thyroid disease

3.49E-03

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa05321

Inflammatory bowel disease

3.10E-02

P01375, Q14765, Q9UL17, P23771, P01584

TNF, STAT4, TBX21, GATA3, IL1B

Calcium-phosphate-dihydrate

hsa05322

Systemic lupus erythematosus

2.13E-03

P08246, P09871, P10747, P13765, Q6FI13, P68431, P05455

ELA2, C1S, CD28, HLA-DOB, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SSB

Calcium-phosphate-dihydrate

hsa05323

Rheumatoid arthritis

2.00E-02

Q13488, P10747, O60603

TCIRG1, CD28, TLR2

Calcium-phosphate-dihydrate

hsa05330

Allograft rejection

3.49E-03

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa05332

Graft-versus-host disease

4.45E-03

P01889, P10321

HLA-B, HLA-C

Calcium-phosphate-dihydrate

hsa05340

Primary immunodeficiency

3.69E-03

P01730, P11912, P07766

CD4, CD79A, CD3E

Calcium-phosphate-dihydrate

hsa05410

Hypertrophic cardiomyopathy

1.02E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05412

Arrhythmogenic right ventricular cardiomyopathy

3.22E-05

P54284, P23229, P16144, P60709, P63261, P35609

CACNB3, ITGA6, ITGB4, ACTB, ACTG1, ACTN2

Calcium-phosphate-dihydrate

hsa05414

Dilated cardiomyopathy

1.73E-02

P60709, P63261

ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05415

Diabetic cardiomyopathy

4.23E-04

P05141, P45880, O15239, O95298, P05496, P13073, P12074, Q13557

SLC25A5, VDAC2, NDUFA1, NDUFC2, ATP5G1, COX4I1, COX6A1, CAMK2D

Calcium-phosphate-dihydrate

hsa05416

Viral myocarditis

1.06E-04

P01889, P10321, P60709, P63261

HLA-B, HLA-C, ACTB, ACTG1

Calcium-phosphate-dihydrate

hsa05418

Fluid shear stress and atherosclerosis

3.64E-03

P14598, P78417, P60709, P63261, P10415, P0DP23, P08238, Q92974

NCF1, GSTO1, ACTB, ACTG1, BCL2, CALM1, HSP90AB1, ARHGEF2

UniProtAC	Gene Name	Protein Name	Reported/ Predicted	DisGeNET	S_PV	S_drugability	S_HiSBiN	S_DisG

PharmaCoNets of Calcium-phosphate-dihydrate (SPCN: 32.32 )

Calcium-phosphate-dihydrate regulated-network (SDN: 27.87)

Community members of Calcium-phosphate-dihydrate (SDC: 1.16)

PharmaCoNets of Calcium-phosphate-dihydrate (S_PCN: 32.32 )

Calcium-phosphate-dihydrate regulated-network (S_DN: 27.87)

Community members of Calcium-phosphate-dihydrate (S_DC: 1.16)