PharmaCoNets of Bifonazole (SPCN: 285.03 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Bifonazolehsa00010Glycolysis / Gluconeogenesis1.89E-035P04075, P14550, P11766, P07195, P60174ALDOA, AKR1A1, ADH5, LDHB, TPI1More
Bifonazolehsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Bifonazolehsa00030Pentose phosphate pathway1.90E-134P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Bifonazolehsa00040Pentose and glucuronate interconversions3.53E-021O60701UGDHMore
Bifonazolehsa00051Fructose and mannose metabolism2.63E-055P15121, P19367, P08237, P60174, P04075AKR1B1, HK1, PFKM, TPI1, ALDOAMore
Bifonazolehsa00052Galactose metabolism7.45E-086P06280, P08237, O43451, P15121, P19367, Q14376GLA, PFKM, MGAM, AKR1B1, HK1, GALEMore
Bifonazolehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Bifonazolehsa00071Fatty acid degradation2.44E-045P11310, O75521, P00325, P11766, P33121ACADM, ECI2, ADH1B, ADH5, ACSL1More
Bifonazolehsa00100Steroid biosynthesis3.94E-021P35610SOAT1More
Bifonazolehsa00190Oxidative phosphorylation3.93E-104Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Bifonazolehsa00220Arginine biosynthesis4.30E-083P15104, P05089, P49448GLUL, ARG1, GLUD2More
Bifonazolehsa00230Purine metabolism3.35E-022Q7LG56, P51828RRM2B, ADCY7More
Bifonazolehsa00240Pyrimidine metabolism3.59E-032P31350, P04818RRM2, TYMSMore
Bifonazolehsa00250Alanine, aspartate and glutamate metabolism6.84E-053Q96RQ9, P49448, P15104IL4I1, GLUD2, GLULMore
Bifonazolehsa00270Cysteine and methionine metabolism2.39E-022Q96RQ9, P40926IL4I1, MDH2More
Bifonazolehsa00280Valine, leucine and isoleucine degradation8.82E-066P55809, Q9HCC0, Q96RQ9, P05166, Q02252, P11310OXCT1, MCCC2, IL4I1, PCCB, ALDH6A1, ACADMMore
Bifonazolehsa00310Lysine degradation2.14E-057Q9NVH6, Q96KQ7, Q8NEZ4, Q13029, O15047, Q02809, P51648TMLHE, EHMT2, MLL3, PRDM2, SETD1A, PLOD1, ALDH3A2More
Bifonazolehsa00330Arginine and proline metabolism2.73E-021P17707AMD1More
Bifonazolehsa00340Histidine metabolism4.52E-021O95954FTCDMore
Bifonazolehsa00380Tryptophan metabolism1.07E-033Q16613, P46952, P51648AANAT, HAAO, ALDH3A2More
Bifonazolehsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Bifonazolehsa00471D-Glutamine and D-glutamate metabolism1.54E-032Q7Z3D6, P49448C14orf159, GLUD2More
Bifonazolehsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Bifonazolehsa00500Starch and sucrose metabolism1.03E-124O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Bifonazolehsa00510N-Glycan biosynthesis1.10E-034O94777, P15907, Q9BVK2, Q9NR34DPM2, ST6GAL1, ALG8, MAN1C1More
Bifonazolehsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Bifonazolehsa00513Various types of N-glycan biosynthesis4.83E-021Q9NR34MAN1C1More
Bifonazolehsa00520Amino sugar and nucleotide sugar metabolism2.98E-053Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Bifonazolehsa00531Glycosaminoglycan degradation3.78E-021P15586GNSMore
Bifonazolehsa00532Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate3.68E-021Q9Y2C2USTMore
Bifonazolehsa00533Glycosaminoglycan biosynthesis - keratan sulfate6.96E-041Q9NY97B3GNT2More
Bifonazolehsa00561Glycerolipid metabolism2.21E-023O14494, P06280, P23743PLPP1, GLA, DGKAMore
Bifonazolehsa00562Inositol phosphate metabolism2.42E-057Q9NRR6, P27987, Q13572, Q96PE3, O14732, P19174, P42338INPP5E, ITPKB, ITPK1, INPP4A, IMPA2, PLCG1, PIK3CBMore
Bifonazolehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.28E-032O94777, Q14442DPM2, PIGHMore
Bifonazolehsa00564Glycerophospholipid metabolism3.90E-068P48651, Q9Y6K0, P35790, Q9Y259, P23743, P49619, O14494, Q3LIE5PTDSS1, CEPT1, CHKA, CHKB, DGKA, DGKG, PLPP1, ADPRMMore
Bifonazolehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Bifonazolehsa00590Arachidonic acid metabolism2.48E-033P11712, P09917, P09960CYP2C9, ALOX5, LTA4HMore
Bifonazolehsa00591Linoleic acid metabolism1.48E-031P11712CYP2C9More
Bifonazolehsa00600Sphingolipid metabolism5.84E-045Q9BX95, O14494, Q06136, P06280, P15289SGPP1, PLPP1, FVT1, GLA, ARSAMore
Bifonazolehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Bifonazolehsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.27E-072P06865, O75752HEXA, B3GALNT1More
Bifonazolehsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Bifonazolehsa00620Pyruvate metabolism9.80E-044P40926, P07195, P14550, P11766MDH2, LDHB, AKR1A1, ADH5More
Bifonazolehsa00630Glyoxylate and dicarboxylate metabolism9.75E-124P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Bifonazolehsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Bifonazolehsa00670One carbon pool by folate2.35E-063O95954, P04818, Q99707FTCD, TYMS, MTRMore
Bifonazolehsa00730Thiamine metabolism7.61E-082P05186, P24666ALPL, ACP1More
Bifonazolehsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Bifonazolehsa00750Vitamin B6 metabolism4.45E-021O00764PDXKMore
Bifonazolehsa00770Pantothenate and CoA biosynthesis1.12E-054O95498, O95497, Q6ZQY3, Q9NRN7VNN2, VNN1, GADL1, AASDHPPTMore
Bifonazolehsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Bifonazolehsa00790Folate biosynthesis5.29E-044Q92820, P05186, P07101, P42330GGH, ALPL, TH, AKR1C3More
Bifonazolehsa00830Retinol metabolism9.72E-086P00325, P11766, P00352, Q9BPW9, O75911, P11712ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3, CYP2C9More
Bifonazolehsa00860Porphyrin and chlorophyll metabolism2.26E-033P36551, P53004, P30043CPOX, BLVRA, BLVRBMore
Bifonazolehsa00900Terpenoid backbone biosynthesis4.22E-022P49354, Q9UHG3FNTA, PCYOX1More
Bifonazolehsa00910Nitrogen metabolism4.40E-032P15104, P49448GLUL, GLUD2More
Bifonazolehsa00970Aminoacyl-tRNA biosynthesis6.74E-104O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Bifonazolehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-054Q16772, P78417, P09211, P11712GSTA3, GSTO1, GSTP1, CYP2C9More
Bifonazolehsa00982Drug metabolism - cytochrome P4501.77E-044P11712, Q16772, P09211, P78417CYP2C9, GSTA3, GSTP1, GSTO1More
Bifonazolehsa00983Drug metabolism - other enzymes6.59E-096P04183, P20839, P32320, P05164, Q16772, P09211TK1, IMPDH1, CDA, MPO, GSTA3, GSTP1More
Bifonazolehsa01040Biosynthesis of unsaturated fatty acids4.28E-021P22307SCP2More
Bifonazolehsa01100Metabolic pathways4.24E-0979Q9NR34, Q9Y234, P35790, Q9Y259, P05089, P21953, Q16772, P09211, Q9UJ14, P30041, P15104, P19367, P42338, Q9Y217, P48426, P27987, Q96DU7, P22557, Q6ZQY3, P32320, Q08828, Q13956, Q02153, P20839, P22748, P40926, P55809, P06280, O94777, Q16875, O43286, O43451, P53004, Q7KZN9, Q9Y6K0, P05186, P24666, P15121, P08237, P49619, Q86XP1, O95861, Q96RQ9, O95954, Q9HCC0, P33121, Q02318, Q9UHK6, Q86VZ5, Q96G23, P09917, P48651, Q9BVK2, P57054, Q14442, Q9UBX8, Q9UNP4, Q9H4F1, Q9BX95, Q9BRR6, P32321, P49448, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P35573, P06737, Q9BQB6, Q969G6, P05166, P14927, P12074, P05496, Q99437, O15239, O15047, Q9NVH6MAN1C1, LIPT1, CHKA, CHKB, ARG1, BCKDHB, GSTA3, GSTP1, GGTL3, PRDX6, GLUL, HK1, PIK3CB, MTMR6, PIP4K2A, ITPKB, ITPKC, ALAS2, GADL1, CDA, ADCY1, PDE6H, GUCY1B3, IMPDH1, CA4, MDH2, OXCT1, GLA, DPM2, PFKFB3, B4GALT5, MGAM, BLVRA, COX15, CEPT1, ALPL, ACP1, AKR1B1, PFKM, DGKG, DGKH, BPNT1, IL4I1, FTCD, MCCC2, ACSL1, CYP27A1, AMACR, SGMS1, LASS2, ALOX5, PTDSS1, ALG8, PIGP, PIGH, B4GALT6, ST3GAL5, ST6GALNAC4, SGPP1, ADPGK, DCTD, GLUD2, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, AGL, PYGL, VKORC1, RFK, PCCB, UQCRB, COX6A1, ATP5G1, ATP6V0B, NDUFA1, SETD1A, TMLHEMore
Bifonazolehsa01200Carbon metabolism7.14E-034P51854, P52209, P37837, P60891TKTL1, PGD, TALDO1, PRPS1More
Bifonazolehsa012102-Oxocarboxylic acid metabolism6.96E-041P50213IDH3AMore
Bifonazolehsa01212Fatty acid metabolism4.62E-022P33121, P11310ACSL1, ACADMMore
Bifonazolehsa01230Biosynthesis of amino acids1.52E-056P51854, P60891, Q99707, P50213, P05089, P37837TKTL1, PRPS1, MTR, IDH3A, ARG1, TALDO1More
Bifonazolehsa01240Biosynthesis of cofactors2.85E-047Q969G6, P13716, P36551, P22557, O60701, P14618, Q9Y234RFK, ALAD, CPOX, ALAS2, UGDH, PKM2, LIPT1More
Bifonazolehsa01521EGFR tyrosine kinase inhibitor resistance3.18E-042P04049, P08069RAF1, IGF1RMore
Bifonazolehsa01522Endocrine resistance2.90E-058P22694, P04049, Q9UM47, P04637, P42773, P08069, P10415, Q13323PRKACB, RAF1, NOTCH3, TP53, CDKN2C, IGF1R, BCL2, BIKMore
Bifonazolehsa01523Antifolate resistance1.48E-055P41440, Q92820, P04818, P01375, P18054SLC19A1, GGH, TYMS, TNF, ALOX12More
Bifonazolehsa01524Platinum drug resistance3.90E-0610Q13489, Q14790, P48023, Q16772, P09211, P78417, P40692, P23025, P52701, P31751BIRC3, CASP8, FASLG, GSTA3, GSTP1, GSTO1, MLH1, XPA, MSH6, AKT2More
Bifonazolehsa02010ABC transporters1.66E-043P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Bifonazolehsa03010Ribosome5.23E-1524P26373, P62753, P42677, P25398, P32969, P62917, P62829, P46776, P46777, Q9H0U6, Q07020, Q9UHA3, P62888, P62899, P62910, P18077, P61927, P61513, Q02878, P36578, P27635, P50914, P05386, P23396RPL13, RPS6, RPS27, RPS12, RPL9, RPL8, RPL23, RPL27A, RPL5, MRPL18, RPL18, RSL24D1, RPL30, RPL31, RPL32, RPL35A, RPL37, RPL37A, RPL6, RPL4, RPL10, RPL14, RPLP1, RPS3More
Bifonazolehsa03013RNA transport4.91E-2329P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9H307, Q7Z3B4, P35658, P63279, P68104, P47813, O14602, Q14152, P55884, O15371, O75822, P78345, Q9H777, P11940, P20042, Q14240, Q9BZI7, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF1AY, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, ELAC1, PABPC1, EIF2S2, EIF4A2, UPF3B, TACC3, EIF2B1, FMR1, FXR1More
Bifonazolehsa03015mRNA surveillance pathway6.77E-036Q9BZI7, O60942, O43148, O94913, P52298, Q53GS7UPF3B, RNGTT, RNMT, PCF11, NCBP2, GLE1More
Bifonazolehsa03020RNA polymerase1.29E-136P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Bifonazolehsa03022Basal transcription factors2.97E-033P20226, O00268, Q15544TBP, TAF4, TAF11More
Bifonazolehsa03040Spliceosome3.81E-1618Q14562, O43143, O60508, P08579, Q15427, P26368, O75940, P38159, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, SF3B4, U2AF2, SMNDC1, RBMX, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Bifonazolehsa03050Proteasome2.78E-032P55036, P28074PSMD4, PSMB5More
Bifonazolehsa03060Protein export1.16E-104Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Bifonazolehsa03320PPAR signaling pathway2.73E-045Q6PCB7, O00767, Q9UNU6, Q13133, Q02318SLC27A1, SCD, CYP8B1, NR1H3, CYP27A1More
Bifonazolehsa03430Mismatch repair4.38E-021P20585MSH3More
Bifonazolehsa03450Non-homologous end-joining3.17E-032Q9NP87, P13010POLM, XRCC5More
Bifonazolehsa03460Fanconi anemia pathway8.90E-043P40692, O60673, Q9UNA4MLH1, REV3L, POLIMore
Bifonazolehsa04010MAPK signaling pathway8.69E-054P04049, P08069, Q9H2K8, Q12933RAF1, IGF1R, TAOK3, TRAF2More
Bifonazolehsa04012ErbB signaling pathway2.36E-0710P21860, Q13153, P16333, Q13191, Q13557, P19174, O14944, P42338, P01106, P04049ERBB3, PAK1, NCK1, CBLB, CAMK2D, PLCG1, EREG, PIK3CB, MYC, RAF1More
Bifonazolehsa04014Ras signaling pathway1.59E-0614P04049, P31751, P42338, P20827, Q9NRA1, P49767, P08069, Q13009, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174RAF1, AKT2, PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Bifonazolehsa04015Rap1 signaling pathway5.10E-0715P04049, P20827, Q9NRA1, P49767, P08069, P06213, Q96FS4, P11215, Q13009, O00522, Q7LDG7, P42338, P31751, P0DP23, P19174RAF1, EFNA1, PDGFC, VEGFC, IGF1R, INSR, SIPA1, ITGAM, TIAM1, KRIT1, RASGRP2, PIK3CB, AKT2, CALM1, PLCG1More
Bifonazolehsa04020Calcium signaling pathway1.26E-1118P27987, Q96DU7, Q08828, P21796, P45880, Q16566, Q13557, P21860, P30679, O15399, P19174, P0DP24, P0DP23, P05141, P51828, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK4, CAMK2D, ERBB3, GNA15, GRIN2D, PLCG1, CALM2, CALM1, SLC25A5, ADCY7, ATP2B4, PDGFC, VEGFCMore
Bifonazolehsa04022cGMP-PKG signaling pathway2.03E-0812Q02153, P04049, Q99941, P18848, P23634, P31751, Q08828, P51828, P05141, P45880, P0DP24, P0DP23GUCY1B3, RAF1, CREBL1, ATF4, ATP2B4, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, CALM2, CALM1More
Bifonazolehsa04024cAMP signaling pathway2.01E-059Q08828, P51828, P42338, P31751, P0DP23, P04049, Q13370, Q13009, Q13153ADCY1, ADCY7, PIK3CB, AKT2, CALM1, RAF1, PDE3B, TIAM1, PAK1More
Bifonazolehsa04060Cytokine-cytokine receptor interaction6.46E-0517P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, Q9HBE5, P78552, P25024, Q9UBD3, P47992, P09341, P19875, P80075, P01730, Q93038IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL21R, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CXCL2, CCL8, CD4, TNFRSF25More
Bifonazolehsa04061Viral protein interaction with cytokine and cytokine receptor2.88E-0711Q8NHW4, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Bifonazolehsa04062Chemokine signaling pathway5.86E-1224P25024, P25025, P09341, P19875, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q7LDG7, Q13009, P14598, P42224, P04049, P25963, P49841, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, RASGRP2, TIAM1, NCF1, STAT1, RAF1, NFKBIA, GSK3B, PIK3R5More
Bifonazolehsa04064NF-kappa B signaling pathway4.42E-1926P10415, Q13489, P51617, O00463, Q13546, P14778, P01584, P01375, P29965, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9UNE0, Q9NQC7BCL2, BIRC3, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, CD40LG, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, EDAR, CYLDMore
Bifonazolehsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Bifonazolehsa04068FoxO signaling pathway4.41E-054P04049, P08069, P48023, Q96BR1RAF1, IGF1R, FASLG, SGK3More
Bifonazolehsa04070Phosphatidylinositol signaling system4.66E-0813P19174, P0DP23, Q14643, P42338, O14986, P23743, P49619, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIK3CB, PIP5K1B, DGKA, DGKG, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Bifonazolehsa04071Sphingolipid signaling pathway4.12E-0812P04049, P17252, P21453, Q9H228, P01375, Q96G23, Q13362, Q9BX95, P10415, Q9UQC2, Q12933, Q02156RAF1, PRKCA, S1PR1, EDG8, TNF, LASS2, PPP2R5C, SGPP1, BCL2, GAB2, TRAF2, PRKCEMore
Bifonazolehsa04072Phospholipase D signaling pathway2.30E-0616P04049, P31751, P42338, Q9UQC2, P43657, P25024, P25025, P19174, O14986, Q14344, Q15438, Q08828, P51828, P23743, Q16760, Q9NRA1RAF1, AKT2, PIK3CB, GAB2, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNA13, PSCD1, ADCY1, ADCY7, DGKA, DGKD, PDGFCMore
Bifonazolehsa04080Neuroactive ligand-receptor interaction1.59E-0814P08311, P28472, P78334, Q15722, P21453, Q9H228, P43657, O00398, P21462, P21730, P30939, P14416, P07550, P35318CTSG, GABRB3, GABRE, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, FPR1, C5AR1, HTR1F, DRD2, ADRB2, ADMMore
Bifonazolehsa04110Cell cycle5.48E-0812Q9UBD5, P30260, P06493, O60566, Q14683, P04637, P49918, P30304, P33981, P42773, P01106, Q13547ORC3, CDC27, CDK1, BUB1B, SMC1A, TP53, CDKN1C, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Bifonazolehsa04114Oocyte meiosis2.64E-1111Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Bifonazolehsa04115p53 signaling pathway1.41E-035O15151, Q13315, P31350, P06493, P10415MDM4, ATM, RRM2, CDK1, BCL2More
Bifonazolehsa04120Ubiquitin mediated proteolysis1.08E-036Q9UBT2, Q14145, Q13042, P62837, Q15751, Q14669SAE2, KEAP1, CDC16, UBE2D2, HERC1, TRIP12More
Bifonazolehsa04136Autophagy - other7.59E-032O94817, Q9H1Y0ATG12, ATG5More
Bifonazolehsa04137Mitophagy - animal1.41E-033P67870, P19532, P18848CSNK2B, TFE3, ATF4More
Bifonazolehsa04140Autophagy - animal5.46E-0615P08069, Q9Y4H2, P42338, P31751, P04049, Q7L523, Q9NQL2, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, IRS2, PIK3CB, AKT2, RAF1, RRAGA, RRAGD, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Bifonazolehsa04141Protein processing in endoplasmic reticulum8.83E-0716P18848, Q12933, P30101, P07384, O95487, Q15436, P60604, Q99941, O75460, P11142, Q9H3Z4, P07900, P08238, Q9NR31, O95816, Q9UNL2ATF4, TRAF2, PDIA3, CAPN1, SEC24B, SEC23A, UBE2G2, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, BAG2, SSR3More
Bifonazolehsa04142Lysosome1.11E-0511O14773, P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, Q9NRA2, P49279, P61916, Q04900TPP1, HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC17A5, SLC11A1, NPC2, CD164More
Bifonazolehsa04144Endocytosis8.76E-0719Q13191, P0DMV8, P11142, Q9H444, O43633, O75351, P62491, P25024, Q96B97, P43250, Q6WKZ4, Q15438, Q8WU79, Q14161, P14784, O95219, O75154, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, CHMP2A, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, RAB11FIP1, PSCD1, SMAP1L, GIT2, IL2RB, SNX4, RAB11FIP3, SNX12, SNX5More
Bifonazolehsa04145Phagosome5.61E-0814O75015, P60709, P63261, Q15075, Q15080, P14598, Q13509, P68371, Q13488, P05164, P78380, O60603, P35443, P13765FCGR3B, ACTB, ACTG1, EEA1, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Bifonazolehsa04146Peroxisome1.95E-036O00623, O96011, P56589, Q9UKG9, O75521, P33121PEX12, PEX11B, PEX3, CROT, ECI2, ACSL1More
Bifonazolehsa04150mTOR signaling pathway1.32E-035P08069, P04049, Q02750, Q9NQL2, P51812IGF1R, RAF1, MAP2K1, RRAGD, RPS6KA3More
Bifonazolehsa04151PI3K-Akt signaling pathway1.55E-0940P62753, P42338, P21860, P43657, P25116, P01106, O43521, P04637, P27348, P20827, Q9NRA1, P49767, Q13362, P07900, P08238, Q8WYR1, P62873, P63218, P50151, P61952, P16144, O15335, P02452, P24821, Q16363, Q13751, P22105, O60603, P14784, P23458, P01568, Q99941, P18848, P10415, P17252, Q96BR1, O00141, Q6ZUJ8, P30281, P56279RPS6, PIK3CB, ERBB3, P2RY5, F2R, MYC, BCL2L11, TP53, YWHAQ, EFNA1, PDGFC, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, PIK3R5, GNB1, GNG5, GNG10, GNG11, ITGB4, CHAD, COL1A1, TNC, LAMA4, LAMB3, TNXB, TLR2, IL2RB, JAK1, IFNA21, CREBL1, ATF4, BCL2, PRKCA, SGK3, SGK, PIK3AP1, CCND3, TCL1AMore
Bifonazolehsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Bifonazolehsa04210Apoptosis1.88E-048O76075, Q14790, P01375, P48023, Q9NR28, Q16548, P42575, P04049DFFB, CASP8, TNF, FASLG, DIABLO, BCL2A1, CASP2, RAF1More
Bifonazolehsa04211Longevity regulating pathway1.55E-059Q12778, P31751, P08069, Q08828, P51828, P18848, Q9UEF7, Q96RR4, Q96KQ7FOXO1, AKT2, IGF1R, ADCY1, ADCY7, ATF4, KL, CAMKK2, EHMT2More
Bifonazolehsa04213Longevity regulating pathway - multiple species2.09E-099P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Bifonazolehsa04215Apoptosis - multiple species1.56E-022Q13489, P10415BIRC3, BCL2More
Bifonazolehsa04217Necroptosis4.69E-1827P01375, Q12933, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, P07384, P0C0S5, Q6FI13, Q99878, Q93077, P10415, Q13557, Q9H444, O43633, O75351, P45880, Q08752TNF, TRAF2, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, CAPN1, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, BCL2, CAMK2D, CHMP4B, CHMP2A, VPS4B, VDAC2, PPIDMore
Bifonazolehsa04218Cellular senescence1.96E-047P31751, P04049, P30281, P0DP23, P01889, P10321, P12236AKT2, RAF1, CCND3, CALM1, HLA-B, HLA-C, SLC25A6More
Bifonazolehsa04260Cardiac muscle contraction4.20E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Bifonazolehsa04261Adrenergic signaling in cardiomyocytes8.65E-1117P09493, P67936, P07550, Q08828, P51828, P22694, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, P0DP24, Q13557, P17252, P10415, P23634TPM1, TPM4, ADRB2, ADCY1, ADCY7, PRKACB, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CALM2, CAMK2D, PRKCA, BCL2, ATP2B4More
Bifonazolehsa04270Vascular smooth muscle contraction3.12E-0711P24723, Q04759, Q14643, P0DP23, P04049, Q08828, P51828, P22694, P35579, P35749, P35318PRKCH, PRKCQ, ITPR1, CALM1, RAF1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Bifonazolehsa04310Wnt signaling pathway2.28E-045P30279, Q13485, O43318, P17612, P67870CCND2, SMAD4, MAP3K7, PRKACA, CSNK2BMore
Bifonazolehsa04330Notch signaling pathway4.48E-054Q92542, P49768, P46531, Q9UM47NCSTN, PSEN1, NOTCH1, NOTCH3More
Bifonazolehsa04340Hedgehog signaling pathway6.28E-065P49841, P17612, P22694, Q13635, P10415GSK3B, PRKACA, PRKACB, PTCH1, BCL2More
Bifonazolehsa04360Axon guidance7.18E-0814P16298, Q05397, P16333, P20827, O95631, Q13873, P42338, P07332, P23528, P04049, P19174, Q06124, O14639, P24844PPP3CB, PTK2, NCK1, EFNA1, NTN1, BMPR2, PIK3CB, FES, CFL1, RAF1, PLCG1, PTPN11, ABLIM1, MYL9More
Bifonazolehsa04370VEGF signaling pathway5.06E-157P19174, P16298, P31751, P42338, Q05397, Q02750, P04049PLCG1, PPP3CB, AKT2, PIK3CB, PTK2, MAP2K1, RAF1More
Bifonazolehsa04371Apelin signaling pathway7.75E-0918P62873, P63218, P50151, P61952, Q8WYR1, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P62753, Q16566, P0DP23, P0DP24GNB1, GNG5, GNG10, GNG11, PIK3R5, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, RPS6, CAMK4, CALM1, CALM2More
Bifonazolehsa04380Osteoclast differentiation2.23E-0914Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Bifonazolehsa04390Hippo signaling pathway2.79E-079O95835, P63261, P84022, Q13485, O15105, P04628, Q9UJU2, O43623, Q13489LATS1, ACTG1, SMAD3, SMAD4, SMAD7, WNT1, LEF1, SNAI2, BIRC3More
Bifonazolehsa04392Hippo signaling pathway - multiple species2.11E-053O95835, Q13153, Q6V0I7LATS1, PAK1, FAT4More
Bifonazolehsa04510Focal adhesion6.34E-0410O75369, Q15942, P51636, Q13489, P10415, P30281, P04049, P08069, P49767, P63261FLNB, ZYX, CAV2, BIRC3, BCL2, CCND3, RAF1, IGF1R, VEGFC, ACTG1More
Bifonazolehsa04512ECM-receptor interaction2.77E-056P02452, P24821, P07359, P26012, P08514, P16070COL1A1, TNC, GP1BA, ITGB8, ITGA2B, CD44More
Bifonazolehsa04520Adherens junction1.81E-033Q13485, O43318, P08069SMAD4, MAP3K7, IGF1RMore
Bifonazolehsa04530Tight junction1.85E-059Q8TEU7, P63261, P16989, P56750, O00501, Q9Y478, Q92974, Q14247, P24844RAPGEF6, ACTG1, CSDA, CLDN17, CLDN5, PRKAB1, ARHGEF2, CTTN, MYL9More
Bifonazolehsa04540Gap junction5.58E-067P17252, P22694, Q13509, P68371, P04049, Q9NRA1, Q14643PRKCA, PRKACB, TUBB3, TUBB2C, RAF1, PDGFC, ITPR1More
Bifonazolehsa04550Signaling pathways regulating pluripotency of stem cells1.61E-035Q13873, P04049, Q02750, P08069, Q86SE9BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Bifonazolehsa04610Complement and coagulation cascades1.51E-104P09871, P0C0L4, P20023, P05107C1S, C4A, CR2, ITGB2More
Bifonazolehsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Bifonazolehsa04612Antigen processing and presentation1.00E-1513P13765, P48382, P01730, Q14953, P26715, P26717, Q07444, Q13241, O43908, P01732, P30101, P11142, P01375HLA-DOB, RFX5, CD4, KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, PDIA3, HSPA8, TNFMore
Bifonazolehsa04613Neutrophil extracellular trap formation2.06E-1236P42338, P19174, P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P04908, P0C0S5, Q6FI13, Q99878, Q93077, P58876, P62807, Q93079, Q16778, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539PIK3CB, PLCG1, PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AC4; H2AC8, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, H2BC5, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Bifonazolehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Bifonazolehsa04620Toll-like receptor signaling pathway9.16E-078Q13546, P01568, P01584, P31751, P42224, P25963, P42338, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, STAT1, NFKBIA, PIK3CB, CCL4L2More
Bifonazolehsa04621NOD-like receptor signaling pathway6.74E-0515P01584, P07900, Q14643, P23458, P01568, P45880, Q13489, P10599, P43490, O00463, Q13546, P29728, P01375, P09341, P12838IL1B, HSP90AA1, ITPR1, JAK1, IFNA21, VDAC2, BIRC3, TXN, PBEF1, TRAF5, RIPK1, OAS2, TNF, CXCL1, DEFA4More
Bifonazolehsa04622RIG-I-like receptor signaling pathway1.16E-085P01568, Q9NQC7, Q13546, Q12933, P10145IFNA21, CYLD, RIPK1, TRAF2, IL8More
Bifonazolehsa04623Cytosolic DNA-sensing pathway1.22E-156P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Bifonazolehsa04625C-type lectin receptor signaling pathway3.16E-1016Q9ULY5, P04049, Q13153, P01584, Q9NQC7, P42224, P20749, P25963, Q14643, P01375, Q13191, P42338, P31751, P0DP24, P0DP23, Q16539CLEC4E, RAF1, PAK1, IL1B, CYLD, STAT1, BCL3, NFKBIA, ITPR1, TNF, CBLB, PIK3CB, AKT2, CALM2, CALM1, MAPK14More
Bifonazolehsa04630JAK-STAT signaling pathway1.01E-048P01106, P31751, P42224, P23458, P14784, P16871, Q13651, P04049MYC, AKT2, STAT1, JAK1, IL2RB, IL7R, IL10RA, RAF1More
Bifonazolehsa04640Hematopoietic cell lineage9.34E-1419P13612, P07359, P08514, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P01584ITGA4, GP1BA, ITGA2B, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, IL1BMore
Bifonazolehsa04650Natural killer cell mediated cytotoxicity6.29E-3320P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, P04049, Q13153, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, PAK1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Bifonazolehsa04657IL-17 signaling pathway3.68E-1115P25963, P07900, P08238, O00463, Q12933, Q07955, Q16539, P49841, P09341, P19875, P14780, P80188, P01375, P06702, P01584NFKBIA, HSP90AA1, HSP90AB1, TRAF5, TRAF2, SFRS1, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNF, S100A9, IL1BMore
Bifonazolehsa04658Th1 and Th2 cell differentiation2.34E-3918P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, Q9UM47, P13765, P23458, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, JAK1, RUNX3More
Bifonazolehsa04659Th17 cell differentiation3.42E-3122P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Bifonazolehsa04660T cell receptor signaling pathway1.09E-2719P01375, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, Q13153, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, PAK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Bifonazolehsa04662B cell receptor signaling pathway1.66E-1414P25963, P31751, P42338, P20023, P60033, P13164, P16298, Q8WV28, P07948, P11912, P21854, Q8N149, Q02750, P04049NFKBIA, AKT2, PIK3CB, CR2, CD81, IFITM1, PPP3CB, BLNK, LYN, CD79A, CD72, LILRA2, MAP2K1, RAF1More
Bifonazolehsa04664Fc epsilon RI signaling pathway5.50E-1010P01375, P31751, Q16539, P42338, Q9UQC2, P07948, P19174, P04049, P09917, P20292TNF, AKT2, MAPK14, PIK3CB, GAB2, LYN, PLCG1, RAF1, ALOX5, ALOX5APMore
Bifonazolehsa04666Fc gamma R-mediated phagocytosis2.42E-049P08637, O75015, P07948, P42338, P19174, P04049, P23528, P06396, P14598FCGR3A, FCGR3B, LYN, PIK3CB, PLCG1, RAF1, CFL1, GSN, NCF1More
Bifonazolehsa04668TNF signaling pathway7.83E-0712P01375, Q12933, O00463, Q16539, Q99941, P18848, P19875, P01584, P20749, P14780, P20333, O95429TNF, TRAF2, TRAF5, MAPK14, CREBL1, ATF4, CXCL2, IL1B, BCL3, MMP9, TNFRSF1B, BAG4More
Bifonazolehsa04670Leukocyte transendothelial migration4.66E-024P11215, P60709, P19174, P12814ITGAM, ACTB, PLCG1, ACTN1More
Bifonazolehsa04672Intestinal immune network for IgA production3.36E-044P29965, P10747, P13765, P13612CD40LG, CD28, HLA-DOB, ITGA4More
Bifonazolehsa04710Circadian rhythm2.11E-031O15516CLOCKMore
Bifonazolehsa04713Circadian entrainment2.88E-0812P0DP23, P0DP24, Q13557, Q02153, P17252, P62873, P63218, P50151, P61952, Q14643, Q08828, P51828CALM1, CALM2, CAMK2D, GUCY1B3, PRKCA, GNB1, GNG5, GNG10, GNG11, ITPR1, ADCY1, ADCY7More
Bifonazolehsa04714Thermogenesis4.09E-057Q16539, P15336, P63261, P33121, Q9Y478, Q16718, O14521MAPK14, ATF2, ACTG1, ACSL1, PRKAB1, NDUFA5, SDHDMore
Bifonazolehsa04720Long-term potentiation4.83E-1212P17252, Q13557, P16298, P0DP23, P0DP24, Q15418, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, CAMK2D, PPP3CB, CALM1, CALM2, RPS6KA1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Bifonazolehsa04721Synaptic vesicle cycle9.45E-042Q13488, P31645TCIRG1, SLC6A4More
Bifonazolehsa04722Neurotrophin signaling pathway1.76E-0610Q05655, P31751, P04049, P49841, O43524, P48023, P52566, P51617, P10415, P0DP23PRKCD, AKT2, RAF1, GSK3B, FOXO3, FASLG, ARHGDIB, IRAK1, BCL2, CALM1More
Bifonazolehsa04723Retrograde endocannabinoid signaling1.69E-037Q14643, P17252, P62873, P61952, Q08828, O15239, Q16718ITPR1, PRKCA, GNB1, GNG11, ADCY1, NDUFA1, NDUFA5More
Bifonazolehsa04724Glutamatergic synapse2.66E-078O15399, Q08828, P62873, P63218, P50151, P61952, P15104, Q9NSB8GRIN2D, ADCY1, GNB1, GNG5, GNG10, GNG11, GLUL, HOMER2More
Bifonazolehsa04725Cholinergic synapse3.27E-0914Q08828, P51828, P22694, Q14643, P17252, P62873, P63218, P50151, P61952, P18848, Q13557, P42338, P31751, P10415ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, GNB1, GNG5, GNG10, GNG11, ATF4, CAMK2D, PIK3CB, AKT2, BCL2More
Bifonazolehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Bifonazolehsa04727GABAergic synapse2.45E-099Q08828, P51828, P62873, P63218, P50151, P61952, P15104, P46459, Q15111ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, NSF, PLCL1More
Bifonazolehsa04728Dopaminergic synapse1.69E-1020Q14643, P17252, P14416, P62873, P63218, P50151, P61952, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP23, P0DP24, O15516, P48058ITPR1, PRKCA, DRD2, GNB1, GNG5, GNG10, GNG11, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM1, CALM2, CLOCK, GRIA4More
Bifonazolehsa04730Long-term depression1.28E-034Q14344, P08069, P04049, P07948GNA13, IGF1R, RAF1, LYNMore
Bifonazolehsa04740Olfactory transduction4.52E-054P62873, Q13557, P0DP23, P0DP24GNB1, CAMK2D, CALM1, CALM2More
Bifonazolehsa04742Taste transduction1.18E-032P30939, P17612HTR1F, PRKACAMore
Bifonazolehsa04744Phototransduction2.51E-103P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Bifonazolehsa04750Inflammatory mediator regulation of TRP channels2.57E-1314P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Bifonazolehsa04810Regulation of actin cytoskeleton2.03E-0310P12814, Q13009, P04049, P42338, P11215, P16144, Q14344, Q9NRA1, P60709, P01042ACTN1, TIAM1, RAF1, PIK3CB, ITGAM, ITGB4, GNA13, PDGFC, ACTB, KNG1More
Bifonazolehsa04910Insulin signaling pathway2.43E-056P0DP23, P22694, P06737, P04049, P31751, P49841CALM1, PRKACB, PYGL, RAF1, AKT2, GSK3BMore
Bifonazolehsa04911Insulin secretion4.38E-085Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Bifonazolehsa04912GnRH signaling pathway5.96E-0712P17252, Q08828, P51828, P18848, Q16539, Q9Y6R4, Q14643, P0DP23, P0DP24, P22694, P04049, P45985PRKCA, ADCY1, ADCY7, ATF4, MAPK14, MAP3K4, ITPR1, CALM1, CALM2, PRKACB, RAF1, MAP2K4More
Bifonazolehsa04913Ovarian steroidogenesis5.64E-054P42330, P22694, P06213, P08069AKR1C3, PRKACB, INSR, IGF1RMore
Bifonazolehsa04914Progesterone-mediated oocyte maturation5.99E-1110P08069, Q17RY0, P42338, Q13370, Q9Y6D9, P30304, P08238, P51812, Q02750, P04049IGF1R, CPEB4, PIK3CB, PDE3B, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Bifonazolehsa04915Estrogen signaling pathway1.37E-1012P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, P0DP24, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Bifonazolehsa04916Melanogenesis7.31E-044P0DP23, Q08828, P51828, P04049CALM1, ADCY1, ADCY7, RAF1More
Bifonazolehsa04917Prolactin signaling pathway3.49E-042P31751, P04049AKT2, RAF1More
Bifonazolehsa04918Thyroid hormone synthesis2.47E-045Q08828, Q99941, P18848, P02768, P05543ADCY1, CREBL1, ATF4, ALB, SERPINA7More
Bifonazolehsa04919Thyroid hormone signaling pathway3.02E-0611P49841, P19174, P04049, P42224, P22694, P60709, Q13547, O60244, Q9NVC6, Q9UM47, P01106GSK3B, PLCG1, RAF1, STAT1, PRKACB, ACTB, HDAC1, MED14, MED17, NOTCH3, MYCMore
Bifonazolehsa04920Adipocytokine signaling pathway3.41E-033Q06124, Q9Y478, P31751PTPN11, PRKAB1, AKT2More
Bifonazolehsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Bifonazolehsa04922Glucagon signaling pathway3.10E-047P14618, P06737, Q12778, P31751, Q13370, P0DP23, Q14643PKM2, PYGL, FOXO1, AKT2, PDE3B, CALM1, ITPR1More
Bifonazolehsa04923Regulation of lipolysis in adipocytes4.29E-077Q08828, P51828, P07550, P06213, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, INSR, PIK3CB, IRS2, AKT2More
Bifonazolehsa04924Renin secretion8.93E-115P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Bifonazolehsa04925Aldosterone synthesis and secretion3.39E-108Q99941, P18848, Q08828, P51828, P0DP24, P0DP23, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM2, CALM1, CAMK2D, ATP2B4More
Bifonazolehsa04926Relaxin signaling pathway5.04E-1017P31751, P25963, P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P22694, P49767, P14780, Q08828, P51828, P04049, P30679, P49407AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, PRKACB, VEGFC, MMP9, ADCY1, ADCY7, RAF1, GNA15, ARRB1More
Bifonazolehsa04927Cortisol synthesis and secretion7.83E-086Q14643, Q99941, P18848, Q08828, P51828, P22694ITPR1, CREBL1, ATF4, ADCY1, ADCY7, PRKACBMore
Bifonazolehsa04928Parathyroid hormone synthesis, secretion and action2.75E-035Q14643, P22694, P23771, P04049, P10415ITPR1, PRKACB, GATA3, RAF1, BCL2More
Bifonazolehsa04929GnRH secretion6.93E-064P42338, P31751, P49407, P04049PIK3CB, AKT2, ARRB1, RAF1More
Bifonazolehsa04930Type II diabetes mellitus6.29E-053P06213, Q05655, Q02156INSR, PRKCD, PRKCEMore
Bifonazolehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Bifonazolehsa04932Non-alcoholic fatty liver disease2.57E-1416P31751, P01375, P49841, Q14790, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, Q16718, O95298, P19404, O14521AKT2, TNF, GSK3B, CASP8, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHDMore
Bifonazolehsa04933AGE-RAGE signaling pathway in diabetic complications8.03E-059P84022, Q13485, P42224, P10415, P42338, Q12778, P49767, P17252, P19174SMAD3, SMAD4, STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1More
Bifonazolehsa04934Cushing syndrome1.05E-099Q14643, Q99941, P18848, Q08828, P51828, P22694, O15169, Q13557, P04628ITPR1, CREBL1, ATF4, ADCY1, ADCY7, PRKACB, AXIN1, CAMK2D, WNT1More
Bifonazolehsa04935Growth hormone synthesis, secretion and action5.87E-046Q08828, P51828, P04049, P18848, P31751, P45985ADCY1, ADCY7, RAF1, ATF4, AKT2, MAP2K4More
Bifonazolehsa04940Type I diabetes mellitus7.38E-044P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Bifonazolehsa04960Aldosterone-regulated sodium reabsorption7.59E-032O00141, P06213SGK, INSRMore
Bifonazolehsa04962Vasopressin-regulated water reabsorption7.22E-032P52566, P62491ARHGDIB, RAB11AMore
Bifonazolehsa04964Proximal tubule bicarbonate reclamation2.17E-031P00918CA2More
Bifonazolehsa04966Collecting duct acid secretion1.26E-043Q13488, P00918, Q9Y666TCIRG1, CA2, SLC12A7More
Bifonazolehsa04970Salivary secretion8.71E-1210P07550, Q08828, P51828, P22694, Q14643, P23634, P0DP24, P0DP23, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B4, CALM2, CALM1, GUCY1B3, CAMPMore
Bifonazolehsa04971Gastric acid secretion1.49E-086Q08828, P51828, P15311, P0DP24, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM2, CALM1, CAMK2DMore
Bifonazolehsa04972Pancreatic secretion1.31E-022Q08828, P62491ADCY1, RAB11AMore
Bifonazolehsa04973Carbohydrate digestion and absorption4.61E-033O43451, P42338, P31751MGAM, PIK3CB, AKT2More
Bifonazolehsa04974Protein digestion and absorption1.22E-032Q7Z2H8, P02452SLC36A1, COL1A1More
Bifonazolehsa04975Fat digestion and absorption4.84E-051O14494PLPP1More
Bifonazolehsa04976Bile secretion1.21E-076O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Bifonazolehsa04979Cholesterol metabolism1.37E-023P38571, P61916, P45880LIPA, NPC2, VDAC2More
Bifonazolehsa05010Alzheimer disease1.31E-1027P49768, Q92542, O15239, Q16718, O95298, P19404, O14521, P05496, P13073, P12074, Q14643, Q00535, O75460, P0DP23, P01584, Q12933, P18848, Q13509, P68371, O15169, P67870, P31751, P05141, P45880, Q08752, P28070, P43686PSEN1, NCSTN, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, CDK5, ERN1, CALM1, IL1B, TRAF2, ATF4, TUBB3, TUBB2C, AXIN1, CSNK2B, AKT2, SLC25A5, VDAC2, PPID, PSMB4, PSMC4More
Bifonazolehsa05012Parkinson disease8.03E-0623O15239, Q16718, O95298, O14521, P13073, P12074, P05496, P05141, P12236, P21796, P60604, O75460, P18848, P28070, P43686, Q14643, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509, P68371NDUFA1, NDUFA5, NDUFC2, SDHD, COX4I1, COX6A1, ATP5G1, SLC25A5, SLC25A6, VDAC1, UBE2G2, ERN1, ATF4, PSMB4, PSMC4, ITPR1, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3, TUBB2CMore
Bifonazolehsa05014Amyotrophic lateral sclerosis6.58E-0315P01375, Q16718, P19404, O14521, P12074, P36542, O75460, P28070, Q8TEV9, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, NDUFV2, SDHD, COX6A1, ATP5C1, ERN1, PSMB4, SMCR8, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Bifonazolehsa05016Huntington disease8.53E-0915O95298, P19404, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, P05141, P45880, Q9NYC9, O75460, P28070, O00232NDUFC2, NDUFV2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, VDAC2, DNAH9, ERN1, PSMB4, PSMD12More
Bifonazolehsa05017Spinocerebellar ataxia1.13E-0410Q92915, O75460, Q8TB72, O15399, P42338, P31751, P28070, P28074, P05141, P21796FGF14, ERN1, PUM2, GRIN2D, PIK3CB, AKT2, PSMB4, PSMB5, SLC25A5, VDAC1More
Bifonazolehsa05020Prion disease4.97E-0926P01584, P46531, P0DMV8, P11142, O15239, Q16718, O95298, O14521, P05496, P13073, P12074, Q14643, P18848, P05141, P12236, P45880, P28070, P43686, Q13509, P68371, P49841, P67870, Q99941, P14598, Q15080, Q16539IL1B, NOTCH1, HSPA1A, HSPA8, NDUFA1, NDUFA5, NDUFC2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, ATF4, SLC25A5, SLC25A6, VDAC2, PSMB4, PSMC4, TUBB3, TUBB2C, GSK3B, CSNK2B, CREBL1, NCF1, NCF4, MAPK14More
Bifonazolehsa05022Pathways of neurodegeneration - multiple diseases4.79E-1240Q14643, O15399, Q13509, P68371, P49841, P67870, P10415, O15239, Q16718, O95298, P19404, O14521, P13073, P12074, P05496, Q06055, Q8TEV9, O75460, P18848, Q12933, Q13561, P05141, P45880, P17252, Q16539, P07384, Q15078, Q00535, O15169, P04628, P01584, P49768, Q08752, O15020, P0DP23, P0DP24, Q13557, P62987, P28070, P43686ITPR1, GRIN2D, TUBB3, TUBB2C, GSK3B, CSNK2B, BCL2, NDUFA1, NDUFA5, NDUFC2, NDUFV2, SDHD, COX4I1, COX6A1, ATP5G1, ATP5G2, SMCR8, ERN1, ATF4, TRAF2, DCTN2, SLC25A5, VDAC2, PRKCA, MAPK14, CAPN1, CDK5R1, CDK5, AXIN1, WNT1, IL1B, PSEN1, PPID, SPTBN2, CALM1, CALM2, CAMK2D, UBA52, PSMB4, PSMC4More
Bifonazolehsa05030Cocaine addiction5.99E-033Q00535, Q99941, P18848CDK5, CREBL1, ATF4More
Bifonazolehsa05031Amphetamine addiction6.41E-067P0DP24, P0DP23, Q13557, P22694, Q99941, P18848, Q13547CALM2, CALM1, CAMK2D, PRKACB, CREBL1, ATF4, HDAC1More
Bifonazolehsa05032Morphine addiction4.50E-047P62873, P63218, P50151, Q13370, P78334, P32298, P43250GNB1, GNG5, GNG10, PDE3B, GABRE, GRK4, GRK6More
Bifonazolehsa05033Nicotine addiction2.83E-033P28472, P78334, O15399GABRB3, GABRE, GRIN2DMore
Bifonazolehsa05034Alcoholism3.38E-1020Q99941, P18848, Q13547, P0DP23, P0DP24, Q96RR4, P62873, P63218, P50151, P61952, P04049, P0C0S5, Q93077, P58876, P62807, Q93079, Q16778, O60814, P84243, P68431CREBL1, ATF4, HDAC1, CALM1, CALM2, CAMKK2, GNB1, GNG5, GNG10, GNG11, RAF1, H2AFZ, HIST1H2AC, H2BC5, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3F3A, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Bifonazolehsa05100Bacterial invasion of epithelial cells2.23E-044Q14141, Q05397, Q92529, Q96JJ3SEPT6, PTK2, SHC3, ELMO2More
Bifonazolehsa05110Vibrio cholerae infection5.58E-056Q13488, Q99437, P17252, P19174, P17612, P60709TCIRG1, ATP6V0B, PRKCA, PLCG1, PRKACA, ACTBMore
Bifonazolehsa05120Epithelial cell signaling in Helicobacter pylori infection4.15E-1511Q16539, Q99437, Q13153, P09341, P19875, P10145, P19174, P25024, P25025, P41240, P07948MAPK14, ATP6V0B, PAK1, CXCL1, CXCL2, IL8, PLCG1, CXCR1, CXCR2, CSK, LYNMore
Bifonazolehsa05130Pathogenic Escherichia coli infection1.02E-0413P16333, Q92974, Q13509, P60709, P63261, P25963, P04406, P29350, Q06124, Q15438, P35579, P55061, O95487NCK1, ARHGEF2, TUBB3, ACTB, ACTG1, NFKBIA, GAPDH, PTPN6, PTPN11, PSCD1, MYH9, TEGT, SEC24BMore
Bifonazolehsa05131Shigellosis3.55E-0618Q12933, Q13546, P68431, Q05655, Q02156, Q9UDY8, Q9NQL2, P0CG47, Q14141, Q14247, Q96JJ3, Q05397, Q14643, Q12778, Q13315, P10415, Q08752, P07737TRAF2, RIPK1, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCD, PRKCE, MALT1, RRAGD, UBB, SEPT6, CTTN, ELMO2, PTK2, ITPR1, FOXO1, ATM, BCL2, PPID, PFN1More
Bifonazolehsa05132Salmonella infection3.05E-1424P51617, P25963, P08238, P04049, Q9UJU2, P01106, P84095, P60709, P63261, P42338, Q13546, Q13489, P10415, P04406, O75369, P07737, O60603, Q9BQS8, Q13561, O60282, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, HSP90AB1, RAF1, LEF1, MYC, RHOG, ACTB, ACTG1, PIK3CB, RIPK1, BIRC3, BCL2, GAPDH, FLNB, PFN1, TLR2, FYCO1, DCTN2, KIF5C, TUBA1A, TUBB3, TUBB2C, VPS41More
Bifonazolehsa05133Pertussis1.55E-063P05107, P10145, P0C0L4ITGB2, IL8, C4AMore
Bifonazolehsa05134Legionellosis1.05E-099P01584, P25963, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Bifonazolehsa05135Yersinia infection2.90E-0614P60709, Q05397, P51812, P13612, P06239, P19174, Q16539, Q02750, P01375, P42338, P49841, Q96JJ3, P01730, P01732ACTB, PTK2, RPS6KA3, ITGA4, LCK, PLCG1, MAPK14, MAP2K1, TNF, PIK3CB, GSK3B, ELMO2, CD4, CD8AMore
Bifonazolehsa05140Leishmaniasis3.51E-1215P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, NCF4More
Bifonazolehsa05142Chagas disease2.70E-022P48023, Q14790FASLG, CASP8More
Bifonazolehsa05143African trypanosomiasis5.79E-064P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Bifonazolehsa05144Malaria4.99E-1110P60033, P69905, P68871, O60603, P01375, P05107, P35443, P01584, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, ITGB2, THBS4, IL1B, IL8, KLRK1More
Bifonazolehsa05145Toxoplasmosis1.02E-037P25963, P10415, Q13489, P42224, P13765, O60603, P29965NFKBIA, BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LGMore
Bifonazolehsa05146Amoebiasis5.19E-2214P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Bifonazolehsa05150Staphylococcus aureus infection1.11E-0915P09871, P0C0L4, P21730, P21462, O75015, P31995, P13765, P13646, Q14532, P05107, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, FCGR2C, HLA-DOB, KRT13, KRT32, ITGB2, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Bifonazolehsa05152Tuberculosis1.83E-0714P04049, Q13488, Q15075, P0DP23, P42224, P48382, O60603, P31751, P10415, P13765, Q13651, P01568, Q9UDY8, P51617RAF1, TCIRG1, EEA1, CALM1, STAT1, RFX5, TLR2, AKT2, BCL2, HLA-DOB, IL10RA, IFNA21, MALT1, IRAK1More
Bifonazolehsa05160Hepatitis C2.07E-0510Q13546, P01568, P60033, O00501, P29728, P04049, P49841, P01375, P48023, P01106RIPK1, IFNA21, CD81, CLDN5, OAS2, RAF1, GSK3B, TNF, FASLG, MYCMore
Bifonazolehsa05161Hepatitis B9.01E-058P04049, Q99941, P18848, P25963, Q13485, P10415, P27348, P84022RAF1, CREBL1, ATF4, NFKBIA, SMAD4, BCL2, YWHAQ, SMAD3More
Bifonazolehsa05162Measles3.90E-0513P01568, P25963, P23458, P42224, P14784, P07766, P42338, P31751, P0DMV8, P11142, P01584, P67870, Q9NP90IFNA21, NFKBIA, JAK1, STAT1, IL2RB, CD3E, PIK3CB, AKT2, HSPA1A, HSPA8, IL1B, CSNK2B, RAB9BMore
Bifonazolehsa05163Human cytomegalovirus infection6.11E-1431P31751, P42338, P04049, P01375, P25963, P62873, P63218, P50151, P61952, Q14643, P0DP23, P0DP24, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P01106, P14778, P01584, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P30101, P61769, P01568AKT2, PIK3CB, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, GNG11, ITPR1, CALM1, CALM2, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, MYC, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, PDIA3, B2M, IFNA21More
Bifonazolehsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Bifonazolehsa05165Human papillomavirus infection7.06E-0517P16144, P02452, P24821, Q16363, Q05086, P30281, Q9UM47, P01568, P42224, P01889, P10321, Q13488, Q99437, Q13362, Q12778, P04628, Q13315ITGB4, COL1A1, TNC, LAMA4, UBE3A, CCND3, NOTCH3, IFNA21, STAT1, HLA-B, HLA-C, TCIRG1, ATP6V0B, PPP2R5C, FOXO1, WNT1, ATMMore
Bifonazolehsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Bifonazolehsa05167Kaposi sarcoma-associated herpesvirus infection2.84E-0919P01568, P31751, P42224, P25963, P42338, P62873, P62879, P63218, P50151, P19174, P16298, Q14643, P04049, Q02750, P07948, P01106, P0DP23, P0CG47, Q9UJU2IFNA21, AKT2, STAT1, NFKBIA, PIK3CB, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, ITPR1, RAF1, MAP2K1, LYN, MYC, CALM1, UBB, LEF1More
Bifonazolehsa05168Herpes simplex virus 1 infection3.44E-0827Q9UKJ0, O00463, Q06124, O60603, P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q16629, Q13489, P30101, P42338, Q9Y2A4, Q13398, P51522, Q9NR11, Q9HCX3, P17097, P17038, Q03923, P52738, O75820, Q9UDV6, P10415PILRB, TRAF5, PTPN11, TLR2, NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, SFRS7, BIRC3, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF302, ZNF304, ZNF7, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212, BCL2More
Bifonazolehsa05169Epstein-Barr virus infection1.36E-0922P20023, P13765, P01106, Q13547, Q92769, O00463, P25963, P10415, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, P01375, O60603, P29728, P07766, P09693, P20963CR2, HLA-DOB, MYC, HDAC1, HDAC2, TRAF5, NFKBIA, BCL2, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, TNF, TLR2, OAS2, CD3E, CD3G, CD247More
Bifonazolehsa05170Human immunodeficiency virus 1 infection1.34E-1124P31751, P42338, P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, Q05397, P17252, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, P19174, P07766, P10415, Q9Y6Q5, P20333AKT2, PIK3CB, RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, PTK2, PRKCA, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, PLCG1, CD3E, BCL2, AP1M2, TNFRSF1BMore
Bifonazolehsa05171Coronavirus disease - COVID-194.96E-1121P01584, P23396, P62753, P25398, P42677, P36578, Q02878, P62917, P32969, P27635, P26373, Q07020, P62888, P46776, P62899, P62910, P18077, P61927, P61513, P05386, P62829IL1B, RPS3, RPS6, RPS12, RPS27, RPL4, RPL6, RPL8, RPL9, RPL10, RPL13, RPL18, RPL30, RPL27A, RPL31, RPL32, RPL35A, RPL37, RPL37A, RPLP1, RPL23More
Bifonazolehsa05200Pathways in cancer8.16E-1140Q13751, P42338, P08238, P42224, P25963, P19174, P01106, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, P52701, Q13547, P14923, P30279, P30281, P10415, Q13489, Q13077, P49767, P14921, Q12778, P31751, P43657, P25116, P62873, P63218, P50151, Q14344, Q7LDG7, Q9UM47, P78417, O75293, P0DP23, P01568, P14784, P40189, P01042LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, MSH6, HDAC1, JUP, CCND2, CCND3, BCL2, BIRC3, TRAF1, VEGFC, ETS1, FOXO1, AKT2, P2RY5, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP2, NOTCH3, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6ST, KNG1More
Bifonazolehsa05202Transcriptional misregulation in cancer5.53E-1022Q12778, Q13315, P41732, P17844, P14780, P27930, Q15744, Q16548, P11215, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, ATM, TSPAN7, DDX5, MMP9, IL1R2, CEBPE, BCL2A1, ITGAM, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Bifonazolehsa05203Viral carcinogenesis1.06E-1024Q12933, Q99941, P18848, P42229, P42338, P06746, P07948, P30281, P27348, P29083, Q13547, Q15283, P06396, P12814, P25963, P01889, P10321, P06493, P58876, P62807, P33778, Q93079, Q16778, O60814TRAF2, CREBL1, ATF4, STAT5A, PIK3CB, POLB, LYN, CCND3, YWHAQ, GTF2E1, HDAC1, RASA2, GSN, ACTN1, NFKBIA, HLA-B, HLA-C, CDK1, H2BC5, HIST1H2BC, H2BC3, H2BC9, HIST2H2BE, H2BC12More
Bifonazolehsa05204Chemical carcinogenesis1.77E-044Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
Bifonazolehsa05205Proteoglycans in cancer9.53E-0615Q13009, Q12955, O75369, P60709, P04049, P14780, P01106, P01375, P08069, P23588, P19174, Q13635, P22694, P29350, P08962TIAM1, ANK3, FLNB, ACTB, RAF1, MMP9, MYC, TNF, IGF1R, EIF4B, PLCG1, PTCH1, PRKACB, PTPN6, CD63More
Bifonazolehsa05206MicroRNAs in cancer1.17E-0414P30304, P09493, P15311, P21860, P01106, P42338, P61978, P46531, Q13547, P63279, P22105, P20827, P19174, P04049CDC25A, TPM1, VIL2, ERBB3, MYC, PIK3CB, HNRPK, NOTCH1, HDAC1, UBE2I, TNXB, EFNA1, PLCG1, RAF1More
Bifonazolehsa05210Colorectal cancer8.05E-0611Q9UKG1, P84022, Q13485, P43246, P04049, P01106, P10415, P52701, P20585, P37173, O75293APPL1, SMAD3, SMAD4, MSH2, RAF1, MYC, BCL2, MSH6, MSH3, TGFBR2, GADD45BMore
Bifonazolehsa05211Renal cell carcinoma1.84E-055Q06124, Q99814, Q13153, P31751, P04049PTPN11, EPAS1, PAK1, AKT2, RAF1More
Bifonazolehsa05212Pancreatic cancer7.75E-079P42338, P31751, P04049, Q15311, P23458, P42224, P84022, Q13485, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, SMAD3, SMAD4, GADD45BMore
Bifonazolehsa05213Endometrial cancer4.41E-044O15169, P31751, Q02750, P04049AXIN1, AKT2, MAP2K1, RAF1More
Bifonazolehsa05214Glioma3.06E-087P08069, P0DP23, P04049, P42338, P31751, P19174, O75293IGF1R, CALM1, RAF1, PIK3CB, AKT2, PLCG1, GADD45BMore
Bifonazolehsa05215Prostate cancer2.34E-045P10415, Q12778, P08069, Q9NRA1, P04049BCL2, FOXO1, IGF1R, PDGFC, RAF1More
Bifonazolehsa05217Basal cell carcinoma6.68E-045Q13635, P04628, P49841, Q9UJU2, P24522PTCH1, WNT1, GSK3B, LEF1, GADD45AMore
Bifonazolehsa05218Melanoma3.78E-056P08069, Q9NRA1, P31751, P42338, P04049, O75293IGF1R, PDGFC, AKT2, PIK3CB, RAF1, GADD45BMore
Bifonazolehsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Bifonazolehsa05220Chronic myeloid leukemia1.24E-069Q13547, P01106, Q13485, P25963, P84022, P31751, P42338, P04049, O75293HDAC1, MYC, SMAD4, NFKBIA, SMAD3, AKT2, PIK3CB, RAF1, GADD45BMore
Bifonazolehsa05221Acute myeloid leukemia8.73E-045P31751, P42338, P04049, Q15744, P11215AKT2, PIK3CB, RAF1, CEBPE, ITGAMMore
Bifonazolehsa05222Small cell lung cancer1.36E-034P31751, Q13489, P10415, P25963AKT2, BIRC3, BCL2, NFKBIAMore
Bifonazolehsa05223Non-small cell lung cancer3.07E-046P17252, O43524, P31751, P19174, P04049, O75293PRKCA, FOXO3, AKT2, PLCG1, RAF1, GADD45BMore
Bifonazolehsa05224Breast cancer2.75E-036P04049, P08069, P49841, Q92837, P04637, P24522RAF1, IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Bifonazolehsa05225Hepatocellular carcinoma1.65E-042P04049, P08069RAF1, IGF1RMore
Bifonazolehsa05226Gastric cancer2.61E-057P04049, Q02750, P31751, O15169, P84022, Q13485, P10415RAF1, MAP2K1, AKT2, AXIN1, SMAD3, SMAD4, BCL2More
Bifonazolehsa05230Central carbon metabolism in cancer1.12E-032P04049, P31751RAF1, AKT2More
Bifonazolehsa05231Choline metabolism in cancer4.99E-1012P04049, P31751, P42338, Q9NRA1, Q9Y259, P19174, P23743, P49619, Q16760, O14986, O14494, P17252RAF1, AKT2, PIK3CB, PDGFC, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PLPP1, PRKCAMore
Bifonazolehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer2.09E-1918P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P04049, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, RAF1, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Bifonazolehsa05310Asthma7.64E-083P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Bifonazolehsa05320Autoimmune thyroid disease1.27E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Bifonazolehsa05321Inflammatory bowel disease1.41E-168O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Bifonazolehsa05322Systemic lupus erythematosus1.63E-1219P08637, O75015, P08246, P08311, P09871, P01375, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, P33778, Q16778, O60814, P68431, P14678, P12814FCGR3A, FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, H2BC3, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SNRPB, ACTN1More
Bifonazolehsa05323Rheumatoid arthritis7.52E-068P01375, Q06643, P13765, Q13488, P10747, P09341, P19875, O60603TNF, LTB, HLA-DOB, TCIRG1, CD28, CXCL1, CXCL2, TLR2More
Bifonazolehsa05330Allograft rejection7.88E-055P13765, P29965, P48023, P10747, P01375HLA-DOB, CD40LG, FASLG, CD28, TNFMore
Bifonazolehsa05332Graft-versus-host disease8.70E-156P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Bifonazolehsa05340Primary immunodeficiency3.46E-066P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Bifonazolehsa05410Hypertrophic cardiomyopathy3.63E-022P26012, P09493ITGB8, TPM1More
Bifonazolehsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Bifonazolehsa05414Dilated cardiomyopathy3.78E-034P54284, P26012, P09493, P26678CACNB3, ITGB8, TPM1, PLNMore
Bifonazolehsa05415Diabetic cardiomyopathy1.65E-0711P17252, P30405, P14598, Q15080, Q16718, O14521, Q16539, P49841, P14780, P37173, P04406PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, MAPK14, GSK3B, MMP9, TGFBR2, GAPDHMore
Bifonazolehsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Bifonazolehsa05418Fluid shear stress and atherosclerosis6.20E-0813Q16539, P31751, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, AKT2, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Bifonazole (SDC: 13.48)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P22001KCNA3Potassium voltageNonegated channel subfamily A member 3Predicted10.13960.505501.0809
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P40925MDH1Malate dehydrogenase, cytoplasmicPredicted00.35660.27460.24260.97
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
Q06609RAD51DNA repair protein RAD51 homolog 1Predicted00.10220.09540.27250.5144
P21453S1PR1Sphingosine 1Nonephosphate receptor 1Predicted10.14340.38470.2211.0621
Q06124PTPN11TyrosineNoneprotein phosphatase nonNonereceptor type 11Predicted10.15130.45660.6131.6017
P30530AXLTyrosineNoneprotein kinase receptor UFOPredicted10.37970.53650.16371.4264
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P01106MYCMyc protoNoneoncogene proteinPredicted00.12370.02911.1198
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
P24666ACP1Low molecular weight phosphotyrosine protein phosphatasePredicted00.07040.10480.23610.481
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P28074PSMB5Proteasome subunit beta typeNone5Predicted10.28390.47230.54391.6305
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
O00767SCDStearoylNoneCoA desaturasePredicted10.16860.1870.19970.6581
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
P49281SLC11A2Natural resistanceNoneassociated macrophage protein 2Predicted10.33250.05050.26620.5334
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
O75469NR1I2Nuclear receptor subfamily 1 group I member 2Predicted10.03150.949301.9143
P15121AKR1B1AldoNoneketo reductase family 1 member B1Predicted10.56830.6290.2141.7562
P31751AKT2RACNonebeta serine/threonineNoneprotein kinasePredicted00.46620.485612.2044
O00141SGKSerine/threonineNoneprotein kinase Sgk1Predicted00.24130.30370.30591.034
P07195LDHBLNonelactate dehydrogenase B chainPredicted00.01670.17490.2310.5892
P11388TOP2ADNA topoisomerase 2NonealphaPredicted00.19920.46590.19271.2242
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
Q9GZR1SENP6SentrinNonespecific protease 6Predicted00.38440.078400.349
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
Q07912TNK2Activated CDC42 kinase 1Predicted00.0090.347200.6988
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
P29350PTPN6TyrosineNoneprotein phosphatase nonNonereceptor type 6Predicted10.28070.24590.56831.2004
O15294OGTUDPNoneNNoneacetylglucosamineNoneNonepeptide NNoneacetylglucosaminyltransferase 110 kDa subunitPredicted00.27390.06020.10210.3594
Q16769QPCTGlutaminylNonepeptide cyclotransferasePredicted00.02450.241600.4954
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
O14976GAKCyclinNoneGNoneassociated kinasePredicted10.57280.256200.7989
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
Q15418RPS6KA1Ribosomal protein S6 kinase alphaNone1Predicted10.8320.32450.41461.4796
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
P24723PRKCHProtein kinase C eta typePredicted00.19550.32940.20480.9614
Q9Y6R4MAP3K4MitogenNoneactivated protein kinase kinase kinase 4Predicted00.35280.24520.1730.8399
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
Q2M2I8AAK1AP2Noneassociated protein kinase 1Predicted10.37690.328800.846
Q9UEE5STK17ASerine/threonineNoneprotein kinase 17APredicted00.35040.337600.8504
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
O43318MAP3K7MitogenNoneactivated protein kinase kinase kinase 7Predicted00.00590.364911.7327
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
P32298GRK4G proteinNonecoupled receptor kinase 4Predicted00.03520.23860.29480.7896
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
Q16513PKN2Serine/threonineNoneprotein kinase N2Predicted00.04210.27780.33910.9157
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
Q9UEW8STK39STE20/SPS1Nonerelated prolineNonealanineNonerich protein kinasePredicted00.25730.245200.6191
Q96BR1SGK3Serine/threonineNoneprotein kinase Sgk3Predicted00.0260.26840.31140.8612
Q9H2K8TAOK3Serine/threonineNoneprotein kinase TAO3Predicted00.06460.24520.14870.6715
Q9P289STK26Serine/threonineNoneprotein kinase 26Predicted10.02850.262800.5399
Q9NQU5PAK6Serine/threonineNoneprotein kinase PAK 6Predicted00.4090.26690.50031.2386
Q8NI60CABC1Atypical kinase COQ8A, mitochondrialPredicted00.62760.245200.8043
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
Q15831STK11Serine/threonineNoneprotein kinase STK11Predicted00.15110.24410.45491.0186
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q8IVW4CDKL3CyclinNonedependent kinaseNonelike 3Predicted00.41490.241600.6906
Q13873BMPR2Bone morphogenetic protein receptor typeNone2Predicted10.34760.24520.35481.019
O75460ERN1Serine/threonineNoneprotein kinase/endoribonuclease IRE1Predicted10.68060.29440.5571.4862
P51617IRAK1InterleukinNone1 receptorNoneassociated kinase 1Predicted00.02380.30.94441.5563
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
Q16566CAMK4Calcium/calmodulinNonedependent protein kinase type IVPredicted00.07180.24410.61761.1417
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
P21860ERBB3Receptor tyrosineNoneprotein kinase erbBNone3Predicted00.1260.27290.47881.0876
P07332FESTyrosineNoneprotein kinase Fes/FpsPredicted00.27220.26280.15130.8131
P07948LYNTyrosineNoneprotein kinase LynPredicted00.0910.53190.6061.7154
Q99759MAP3K3MitogenNoneactivated protein kinase kinase kinase 3Predicted00.35450.24520.43781.1055
P51955NEK2Serine/threonineNoneprotein kinase Nek2Predicted00.65990.369201.0684
Q13153PAK1Serine/threonineNoneprotein kinase PAK 1Predicted10.46470.34710.78191.7084
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
P22694PRKACBcAMPNonedependent protein kinase catalytic subunit betaPredicted00.37370.298411.7836
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
P45985MAP2K4Dual specificity mitogenNoneactivated protein kinase kinase 4Predicted00.42480.24730.74031.4474
Q9Y6E0STK24Serine/threonineNoneprotein kinase 24Predicted00.54580.245200.7634
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
Q8IVH8MAP4K3MitogenNoneactivated protein kinase kinase kinase kinase 3Predicted00.38330.26730.14870.875
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
Q13523PRPF4BSerine/threonineNoneprotein kinase PRP4 homologPredicted00.13760.245200.5593
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
P41240CSKTyrosineNoneprotein kinase CSKPredicted00.69860.36260.10231.1768
O95835LATS1Serine/threonineNoneprotein kinase LATS1Predicted00.43320.24520.02170.7288
O43283MAP3K13MitogenNoneactivated protein kinase kinase kinase 13Predicted00.45650.24520.14870.8674
P51817PRKXcAMPNonedependent protein kinase catalytic subunit PRKXPredicted00.40630.276500.7562
O95747OXSR1Serine/threonineNoneprotein kinase OSR1Predicted00.18390.245200.5825
P09769FGRTyrosineNoneprotein kinase FgrPredicted00.06220.32440.2250.9049
Q02156PRKCEProtein kinase C epsilon typePredicted00.11750.52870.53771.6539
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q9H422HIPK3HomeodomainNoneinteracting protein kinase 3Predicted00.3650.25080.2180.902
O94806PRKD3Serine/threonineNoneprotein kinase D3Predicted00.23120.24340.16920.7715
Q00536PCTK1CyclinNonedependent kinase 16Predicted00.27140.25600.6478
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P20292ALOX5APArachidonate 5NonelipoxygenaseNoneactivating proteinPredicted00.13030.24180.09070.6395
O15164TRIM24Transcription intermediary factor 1NonealphaPredicted00.28070.105500.3514
P16083NQO2Ribosyldihydronicotinamide dehydrogenase [quinone]Predicted00.29580.313400.7747
P33260CYP2C18Cytochrome P450 2C18Predicted10.02390.07560.15280.316
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)