PharmaCoNets of Bendazac (SPCN: 249.43 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Bendazachsa00030Pentose phosphate pathway6.17E-064P06744, P60891, P52209, P37837GPI, PRPS1, PGD, TALDO1More
Bendazachsa00051Fructose and mannose metabolism3.92E-033P15121, P19367, P08237AKR1B1, HK1, PFKMMore
Bendazachsa00052Galactose metabolism3.77E-045P06280, P08237, O43451, P15121, P19367GLA, PFKM, MGAM, AKR1B1, HK1More
Bendazachsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Bendazachsa00190Oxidative phosphorylation3.45E-054Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Bendazachsa00220Arginine biosynthesis1.43E-022P05089, P49448ARG1, GLUD2More
Bendazachsa00230Purine metabolism1.73E-034P31350, P21589, P20839, Q02153RRM2, NT5E, IMPDH1, GUCY1B3More
Bendazachsa00240Pyrimidine metabolism2.54E-043P31350, P21589, P04818RRM2, NT5E, TYMSMore
Bendazachsa00260Glycine, serine and threonine metabolism1.99E-021P22557ALAS2More
Bendazachsa00310Lysine degradation3.01E-043Q96KQ7, Q02809, P51648EHMT2, PLOD1, ALDH3A2More
Bendazachsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Bendazachsa00500Starch and sucrose metabolism3.07E-073O43451, P46976, P06737MGAM, GYG1, PYGLMore
Bendazachsa00512Mucin type O-glycan biosynthesis3.19E-033O95395, Q8N4A0, Q9NY28GCNT3, GALNT4, GALNT8More
Bendazachsa00520Amino sugar and nucleotide sugar metabolism2.24E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Bendazachsa00524Neomycin, kanamycin and gentamicin biosynthesis2.03E-021P35557GCKMore
Bendazachsa00531Glycosaminoglycan degradation4.51E-022P22304, P06865IDS, HEXAMore
Bendazachsa00562Inositol phosphate metabolism2.00E-024P27987, P19174, P42338, Q02252ITPKB, PLCG1, PIK3CB, ALDH6A1More
Bendazachsa00564Glycerophospholipid metabolism3.56E-023P48651, Q9Y6K0, P35790PTDSS1, CEPT1, CHKAMore
Bendazachsa00565Ether lipid metabolism3.00E-031Q8N661TMEM86BMore
Bendazachsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Bendazachsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Bendazachsa00600Sphingolipid metabolism2.68E-022P07602, Q13510PSAP, ASAH1More
Bendazachsa00630Glyoxylate and dicarboxylate metabolism1.08E-082P40925, P15104MDH1, GLULMore
Bendazachsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Bendazachsa00670One carbon pool by folate1.33E-022P04818, Q99707TYMS, MTRMore
Bendazachsa00730Thiamine metabolism1.15E-063Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Bendazachsa00740Riboflavin metabolism4.03E-021P24666ACP1More
Bendazachsa00790Folate biosynthesis1.04E-023Q92820, P05186, P42330GGH, ALPL, AKR1C3More
Bendazachsa00830Retinol metabolism1.48E-031P00325ADH1BMore
Bendazachsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Bendazachsa00920Sulfur metabolism2.29E-021Q16762TSTMore
Bendazachsa00970Aminoacyl-tRNA biosynthesis2.41E-054O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Bendazachsa00980Metabolism of xenobiotics by cytochrome P4509.14E-054Q16772, P78417, P09211, P11712GSTA3, GSTO1, GSTP1, CYP2C9More
Bendazachsa00982Drug metabolism - cytochrome P4501.77E-044P11712, Q16772, P09211, P78417CYP2C9, GSTA3, GSTP1, GSTO1More
Bendazachsa00983Drug metabolism - other enzymes2.06E-045P04183, P32320, P05164, Q16772, P09211TK1, CDA, MPO, GSTA3, GSTP1More
Bendazachsa01100Metabolic pathways1.94E-0445Q9NR34, Q9Y234, P35790, P05089, Q16772, P09211, Q9UJ14, P30041, P19367, P48426, P22557, P32320, P20839, P22748, P40926, P55809, P06280, Q16875, O43286, O43451, Q7KZN9, Q9Y6K0, P05186, P24666, P15121, P08237, O95861, Q9HCC0, P33121, Q9UHK6, Q86VZ5, P48651, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q9BQB6, Q969G6, P14927MAN1C1, LIPT1, CHKA, ARG1, GSTA3, GSTP1, GGTL3, PRDX6, HK1, PIP4K2A, ALAS2, CDA, IMPDH1, CA4, MDH2, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, COX15, CEPT1, ALPL, ACP1, AKR1B1, PFKM, BPNT1, MCCC2, ACSL1, AMACR, SGMS1, PTDSS1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, VKORC1, RFK, UQCRBMore
Bendazachsa01200Carbon metabolism7.69E-033P06744, P37837, P40926GPI, TALDO1, MDH2More
Bendazachsa012102-Oxocarboxylic acid metabolism1.40E-021P50213IDH3AMore
Bendazachsa01230Biosynthesis of amino acids3.59E-023P60891, Q99707, P37837PRPS1, MTR, TALDO1More
Bendazachsa01240Biosynthesis of cofactors4.63E-023Q969G6, P22557, Q9Y234RFK, ALAS2, LIPT1More
Bendazachsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P08069IGF1RMore
Bendazachsa01522Endocrine resistance1.69E-024P22694, P08069, P10415, Q13323PRKACB, IGF1R, BCL2, BIKMore
Bendazachsa01523Antifolate resistance3.45E-075P41439, P41440, Q92820, P04818, P01375FOLR3, SLC19A1, GGH, TYMS, TNFMore
Bendazachsa01524Platinum drug resistance3.80E-034O15392, Q16772, P09211, P11388BIRC5, GSTA3, GSTP1, TOP2AMore
Bendazachsa02010ABC transporters2.17E-031Q8IZY2ABCA7More
Bendazachsa03008Ribosome biogenesis in eukaryotes1.88E-023O14980, O60832, Q9BVP2XPO1, DKC1, GNL3More
Bendazachsa03013RNA transport8.23E-1226P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q7Z3B4, P35658, P63279, P68104, P47813, Q14152, P55884, O15371, O75822, P78345, P20042, Q14240, Q9BZI7, P23588, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, EIF2S2, EIF4A2, UPF3B, EIF4B, TACC3, EIF2B1, FMR1, FXR1More
Bendazachsa03018RNA degradation5.00E-021Q9NQT4EXOSC5More
Bendazachsa03020RNA polymerase8.65E-096P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Bendazachsa03022Basal transcription factors3.50E-023P20226, O00268, Q15544TBP, TAF4, TAF11More
Bendazachsa03030DNA replication5.00E-021P27694RPA1More
Bendazachsa03040Spliceosome3.58E-1317Q14562, O43143, O60508, P08579, Q15427, P26368, P38159, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, SF3B4, U2AF2, RBMX, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Bendazachsa03050Proteasome1.53E-031P55036PSMD4More
Bendazachsa03060Protein export1.28E-032P37108, Q15005SRP14, SPCS2More
Bendazachsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Bendazachsa04010MAPK signaling pathway4.15E-021P08069IGF1RMore
Bendazachsa04012ErbB signaling pathway4.94E-078P21860, P16333, P17252, Q13557, P19174, O14944, P42338, P01106ERBB3, NCK1, PRKCA, CAMK2D, PLCG1, EREG, PIK3CB, MYCMore
Bendazachsa04014Ras signaling pathway4.58E-1016P42338, P20827, Q9NRA1, P49767, P08069, Q13009, P17252, P14921, Q7LDG7, Q15283, P61586, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, PRKCA, ETS1, RASGRP2, RASA2, RHOA, CALM1, GNB1, GNG5, GNG10, PLCG1More
Bendazachsa04015Rap1 signaling pathway4.87E-0715P20827, Q9NRA1, P49767, P08069, Q96FS4, P11215, P25116, Q8TEU7, Q13009, Q7LDG7, P42338, P0DP23, P08514, P17252, P19174EFNA1, PDGFC, VEGFC, IGF1R, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, RASGRP2, PIK3CB, CALM1, ITGA2B, PRKCA, PLCG1More
Bendazachsa04020Calcium signaling pathway3.08E-0818P27987, Q96DU7, Q08828, P21796, P45880, Q13557, P17252, P21860, P30679, O15399, P19174, P61073, P0DP23, P05141, P51828, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK2D, PRKCA, ERBB3, GNA15, GRIN2D, PLCG1, CXCR4, CALM1, SLC25A5, ADCY7, ATP2B4, PDGFC, VEGFCMore
Bendazachsa04022cGMP-PKG signaling pathway2.00E-0512P24844, Q99941, P18848, P23634, Q8WYR1, P31751, Q08828, P51828, P05141, P45880, Q15746, P0DP23MYL9, CREBL1, ATF4, ATP2B4, PIK3R5, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, MYLK, CALM1More
Bendazachsa04024cAMP signaling pathway6.00E-0512Q08828, P51828, P42338, P31751, P0DP23, Q13370, P48058, O15399, P25963, P25116, P24844, Q13009ADCY1, ADCY7, PIK3CB, AKT2, CALM1, PDE3B, GRIA4, GRIN2D, NFKBIA, F2R, MYL9, TIAM1More
Bendazachsa04061Viral protein interaction with cytokine and cytokine receptor3.89E-0510Q8NHW4, P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Bendazachsa04062Chemokine signaling pathway5.49E-1018P25024, P25025, P09341, P19875, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q7LDG7, Q13009, P14598, P42224, P25963, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, NCF1, STAT1, NFKBIA, PIK3R5More
Bendazachsa04064NF-kappa B signaling pathway2.06E-1225P10415, Q13489, P25963, P51617, O00463, Q13546, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9UNE0, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, EDAR, CYLDMore
Bendazachsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Bendazachsa04068FoxO signaling pathway1.99E-021P08069IGF1RMore
Bendazachsa04070Phosphatidylinositol signaling system5.37E-0911P19174, P0DP23, P42338, O14986, P23743, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, PIK3CB, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Bendazachsa04071Sphingolipid signaling pathway8.63E-0910P17252, P21453, Q9H228, P01375, Q13510, Q13362, Q9BX95, Q16539, P10415, Q9UQC2PRKCA, S1PR1, EDG8, TNF, ASAH1, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Bendazachsa04072Phospholipase D signaling pathway1.83E-0616P31751, P42338, Q9UQC2, P43657, P25024, P25025, P19174, O14986, Q14344, Q8WYR1, Q15438, Q08828, P51828, P23743, Q16760, Q9NRA1AKT2, PIK3CB, GAB2, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNA13, PIK3R5, PSCD1, ADCY1, ADCY7, DGKA, DGKD, PDGFCMore
Bendazachsa04080Neuroactive ligand-receptor interaction1.98E-0912P08311, Q15722, P21453, Q9H228, P43657, O00398, P21462, P21730, Q16581, P14416, P07550, P35318CTSG, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, FPR1, C5AR1, C3AR1, DRD2, ADRB2, ADMMore
Bendazachsa04110Cell cycle4.12E-0910Q9UBD5, P06493, O60566, Q14683, O75293, P30304, P33981, P42773, P01106, Q13547ORC3, CDK1, BUB1B, SMC1A, GADD45B, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Bendazachsa04114Oocyte meiosis6.20E-0611Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Bendazachsa04115p53 signaling pathway4.13E-047P24522, Q13315, P31350, Q53FA7, P06493, O95067, P10415GADD45A, ATM, RRM2, TP53I3, CDK1, CCNB2, BCL2More
Bendazachsa04120Ubiquitin mediated proteolysis7.04E-056Q9UBT2, Q13042, Q15751, O95071, Q14669, P0CG47SAE2, CDC16, HERC1, UBR5, TRIP12, UBBMore
Bendazachsa04122Sulfur relay system2.29E-021Q16762TSTMore
Bendazachsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Bendazachsa04137Mitophagy - animal9.52E-032Q07817, P0CG47BCL2L1, UBBMore
Bendazachsa04140Autophagy - animal1.75E-0410P08069, P31751, Q7L523, O75460, P22694, Q14643, P10415, Q04759, Q96GC9, Q8TEV9IGF1R, AKT2, RRAGA, ERN1, PRKACB, ITPR1, BCL2, PRKCQ, TMEM49, SMCR8More
Bendazachsa04141Protein processing in endoplasmic reticulum1.33E-0310P30101, P60604, Q99941, O75460, P11142, Q9H3Z4, P07900, P08238, Q9H173, Q9UNL2PDIA3, UBE2G2, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SIL1, SSR3More
Bendazachsa04142Lysosome1.56E-059P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, P49279, P61916, Q04900HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC11A1, NPC2, CD164More
Bendazachsa04144Endocytosis6.92E-047P0DMV8, Q9H444, O75351, P62491, Q8WU79, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SMAP1L, GIT2, SNX12More
Bendazachsa04145Phagosome5.01E-0812O75015, P11215, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765FCGR3B, ITGAM, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOBMore
Bendazachsa04146Peroxisome4.83E-024O96011, P56589, Q9UKG9, O75521PEX11B, PEX3, CROT, ECI2More
Bendazachsa04150mTOR signaling pathway7.74E-034P08069, Q02750, Q9NQL2, P51812IGF1R, MAP2K1, RRAGD, RPS6KA3More
Bendazachsa04151PI3K-Akt signaling pathway8.01E-0622P42338, P43657, P01106, O43521, P20827, Q9NRA1, P49767, Q13362, P08238, Q8WYR1, P62873, P63218, P50151, P16144, O15335, Q13751, P14784, P23458, P01568, P17252, Q6ZUJ8, P30281PIK3CB, P2RY5, MYC, BCL2L11, EFNA1, PDGFC, VEGFC, PPP2R5C, HSP90AB1, PIK3R5, GNB1, GNG5, GNG10, ITGB4, CHAD, LAMB3, IL2RB, JAK1, IFNA21, PRKCA, PIK3AP1, CCND3More
Bendazachsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Bendazachsa04210Apoptosis1.79E-0412Q13315, P10415, Q13489, O76075, P25963, P01375, P24522, Q16548, Q13077, P43234, P18848, Q14643ATM, BCL2, BIRC3, DFFB, NFKBIA, TNF, GADD45A, BCL2A1, TRAF1, CTSO, ATF4, ITPR1More
Bendazachsa04211Longevity regulating pathway1.96E-048Q12778, P31751, P08069, Q08828, P51828, P18848, Q9UEF7, Q96KQ7FOXO1, AKT2, IGF1R, ADCY1, ADCY7, ATF4, KL, EHMT2More
Bendazachsa04213Longevity regulating pathway - multiple species7.00E-079P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Bendazachsa04217Necroptosis5.05E-0510P01568, Q13489, Q13546, P42224, P08238, P15104, Q6FI13, Q93077, O43633, Q08752IFNA21, BIRC3, RIPK1, STAT1, HSP90AB1, GLUL, H2AC18; H2AC19, HIST1H2AC, CHMP2A, PPIDMore
Bendazachsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Bendazachsa04261Adrenergic signaling in cardiomyocytes9.56E-0714P09493, P67936, Q08828, P51828, Q8WYR1, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, P0DP24, Q13557, P23634TPM1, TPM4, ADCY1, ADCY7, PIK3R5, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CALM2, CAMK2D, ATP2B4More
Bendazachsa04270Vascular smooth muscle contraction2.17E-0613Q15746, P24844, P24723, Q04759, Q14643, P0DP24, P0DP23, Q08828, P51828, P22694, P35579, P35749, P35318MYLK, MYL9, PRKCH, PRKCQ, ITPR1, CALM2, CALM1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Bendazachsa04330Notch signaling pathway4.34E-022Q92542, P46531NCSTN, NOTCH1More
Bendazachsa04340Hedgehog signaling pathway9.48E-054P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Bendazachsa04360Axon guidance2.88E-068P16333, P20827, O95631, P17252, P42338, P07332, P23528, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, FES, CFL1, PLCG1More
Bendazachsa04370VEGF signaling pathway1.13E-066P19174, P16298, P42338, P17252, Q05397, Q02750PLCG1, PPP3CB, PIK3CB, PRKCA, PTK2, MAP2K1More
Bendazachsa04371Apelin signaling pathway4.69E-0813P62873, P63218, P50151, Q8WYR1, P31751, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P0DP23GNB1, GNG5, GNG10, PIK3R5, AKT2, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, CALM1More
Bendazachsa04380Osteoclast differentiation5.27E-0410Q9NQC7, Q9UQC2, Q16539, P23458, P31751, P01584, P14778, O75015, P01375, Q8N149CYLD, GAB2, MAPK14, JAK1, AKT2, IL1B, IL1R1, FCGR3B, TNF, LILRA2More
Bendazachsa04510Focal adhesion3.44E-0413P16144, P08514, O75369, Q15746, P24844, P42338, Q15942, P17252, O15335, Q13751, Q13489, P08069, P49767ITGB4, ITGA2B, FLNB, MYLK, MYL9, PIK3CB, ZYX, PRKCA, CHAD, LAMB3, BIRC3, IGF1R, VEGFCMore
Bendazachsa04512ECM-receptor interaction1.06E-032P07359, P08514GP1BA, ITGA2BMore
Bendazachsa04514Cell adhesion molecules1.55E-044P23229, P16109, P30511, O00501ITGA6, SELP, HLA-F, CLDN5More
Bendazachsa04520Adherens junction8.29E-031P08069IGF1RMore
Bendazachsa04530Tight junction1.14E-046Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Bendazachsa04540Gap junction7.64E-046P22694, Q13509, P68371, Q71U36, Q9NRA1, Q14643PRKACB, TUBB3, TUBB2C, TUBA1A, PDGFC, ITPR1More
Bendazachsa04550Signaling pathways regulating pluripotency of stem cells1.58E-033P04628, P40189, P08069WNT1, IL6ST, IGF1RMore
Bendazachsa04610Complement and coagulation cascades1.38E-084P25116, P00734, P0C0L4, P10909F2R, F2, C4A, CLUMore
Bendazachsa04611Platelet activation1.27E-097P25116, Q9Y490, P08514, Q15746, Q08828, Q8WYR1, P07359F2R, TLN1, ITGA2B, MYLK, ADCY1, PIK3R5, GP1BAMore
Bendazachsa04612Antigen processing and presentation2.02E-099P13765, P48382, P26715, P26717, Q07444, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, TNFMore
Bendazachsa04613Neutrophil extracellular trap formation1.34E-1030P42338, P19174, P17252, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q99878, Q93077, P62807, Q93079, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539PIK3CB, PLCG1, PRKCA, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, H2AC14, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Bendazachsa04620Toll-like receptor signaling pathway7.07E-058Q13546, P01568, P01584, P31751, P42224, P25963, P42338, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, STAT1, NFKBIA, PIK3CB, CCL4L2More
Bendazachsa04621NOD-like receptor signaling pathway6.41E-0618Q16539, Q14643, P23458, P01568, P25963, Q9H3M7, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q13546, Q05823, P01375, P09341, P49913, P12838MAPK14, ITPR1, JAK1, IFNA21, NFKBIA, TXNIP, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RIPK1, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Bendazachsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Bendazachsa04623Cytosolic DNA-sensing pathway7.67E-116P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Bendazachsa04625C-type lectin receptor signaling pathway7.57E-0511Q9ULY5, P01584, Q9NQC7, P42224, P20749, P25963, P01375, P42338, P31751, P0DP23, Q16539CLEC4E, IL1B, CYLD, STAT1, BCL3, NFKBIA, TNF, PIK3CB, AKT2, CALM1, MAPK14More
Bendazachsa04630JAK-STAT signaling pathway3.25E-036P31751, O75925, P23458, P40189, Q13651, Q06124AKT2, PIAS1, JAK1, IL6ST, IL10RA, PTPN11More
Bendazachsa04640Hematopoietic cell lineage8.34E-0717P13612, P21926, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375ITGA4, CD9, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNFMore
Bendazachsa04650Natural killer cell mediated cytotoxicity2.68E-1517P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Bendazachsa04657IL-17 signaling pathway2.02E-057O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Bendazachsa04658Th1 and Th2 cell differentiation4.01E-2116P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Bendazachsa04659Th17 cell differentiation6.74E-1719P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, P40189, Q9UL17, P23771, P84022, Q13485, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL6ST, TBX21, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247More
Bendazachsa04660T cell receptor signaling pathway1.38E-1219P01375, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841TNF, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Bendazachsa04662B cell receptor signaling pathway5.25E-046P25963, P42338, P60033, P07948, P21854, Q8N149NFKBIA, PIK3CB, CD81, LYN, CD72, LILRA2More
Bendazachsa04664Fc epsilon RI signaling pathway2.14E-0810P01375, P04141, Q16539, P42338, P17252, Q9UQC2, P07948, P19174, P09917, P20292TNF, CSF2, MAPK14, PIK3CB, PRKCA, GAB2, LYN, PLCG1, ALOX5, ALOX5APMore
Bendazachsa04666Fc gamma R-mediated phagocytosis4.81E-068P07948, P42338, P19174, P23528, P06396, O14494, P14598, P17252LYN, PIK3CB, PLCG1, CFL1, GSN, PLPP1, NCF1, PRKCAMore
Bendazachsa04668TNF signaling pathway2.41E-0411P01375, O00463, Q13489, Q16539, P25963, Q99941, P01584, P20749, Q13077, P14780, O95429TNF, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, IL1B, BCL3, TRAF1, MMP9, BAG4More
Bendazachsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Bendazachsa04672Intestinal immune network for IgA production1.37E-034P29965, P10747, P13765, P13612CD40LG, CD28, HLA-DOB, ITGA4More
Bendazachsa04710Circadian rhythm2.43E-021O15516CLOCKMore
Bendazachsa04713Circadian entrainment1.09E-058O15399, P0DP23, P17252, P62873, P63218, P50151, Q08828, P51828GRIN2D, CALM1, PRKCA, GNB1, GNG5, GNG10, ADCY1, ADCY7More
Bendazachsa04720Long-term potentiation1.81E-046P16298, P0DP23, P51812, P18848, Q08828, Q02750PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1More
Bendazachsa04721Synaptic vesicle cycle3.15E-022Q13488, P31645TCIRG1, SLC6A4More
Bendazachsa04723Retrograde endocannabinoid signaling3.10E-037Q14643, P17252, P48169, P62873, P22694, Q16539, Q16718ITPR1, PRKCA, GABRA4, GNB1, PRKACB, MAPK14, NDUFA5More
Bendazachsa04724Glutamatergic synapse3.82E-068P48058, O15399, P17252, P62873, P63218, P50151, P15104, Q9NSB8GRIA4, GRIN2D, PRKCA, GNB1, GNG5, GNG10, GLUL, HOMER2More
Bendazachsa04725Cholinergic synapse2.72E-0612Q08828, P51828, P22694, Q14643, P17252, P62873, P63218, P50151, P18848, P42338, P31751, P10415ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, GNB1, GNG5, GNG10, ATF4, PIK3CB, AKT2, BCL2More
Bendazachsa04726Serotonergic synapse2.52E-036P17252, P62873, P63218, P50151, P33260, P09917PRKCA, GNB1, GNG5, GNG10, CYP2C18, ALOX5More
Bendazachsa04727GABAergic synapse2.69E-066P62873, P63218, P50151, P48169, P15104, P17252GNB1, GNG5, GNG10, GABRA4, GLUL, PRKCAMore
Bendazachsa04728Dopaminergic synapse7.83E-035P31751, P18848, Q13362, Q14738, P0DP23AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1More
Bendazachsa04730Long-term depression2.32E-033Q14344, P08069, P07948GNA13, IGF1R, LYNMore
Bendazachsa04742Taste transduction4.80E-021P48169GABRA4More
Bendazachsa04744Phototransduction6.52E-082P62873, P0DP23GNB1, CALM1More
Bendazachsa04750Inflammatory mediator regulation of TRP channels1.17E-0710P14778, P01584, Q08828, P51828, Q13557, P19174, P42338, P24723, Q04759, P0DP23IL1R1, IL1B, ADCY1, ADCY7, CAMK2D, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1More
Bendazachsa04810Regulation of actin cytoskeleton5.47E-0511P12814, P24844, Q15746, Q13009, P42338, P23229, P08514, P11215, Q14344, Q9NRA1, P25116ACTN1, MYL9, MYLK, TIAM1, PIK3CB, ITGA6, ITGA2B, ITGAM, GNA13, PDGFC, F2RMore
Bendazachsa04911Insulin secretion8.29E-045Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Bendazachsa04912GnRH signaling pathway3.05E-059P17252, Q08828, P51828, P18848, Q16539, Q9Y6R4, Q14643, P0DP23, P22694PRKCA, ADCY1, ADCY7, ATF4, MAPK14, MAP3K4, ITPR1, CALM1, PRKACBMore
Bendazachsa04913Ovarian steroidogenesis8.54E-033P42330, P22694, P08069AKR1C3, PRKACB, IGF1RMore
Bendazachsa04914Progesterone-mediated oocyte maturation6.34E-0710P08069, Q17RY0, P42338, Q13370, Q9UJX4, Q9Y6D9, P30304, P08238, P51812, Q02750IGF1R, CPEB4, PIK3CB, PDE3B, ANAPC5, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1More
Bendazachsa04915Estrogen signaling pathway8.22E-0916Q99527, P14780, P22694, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, Q14643, P0DP23, P0DP24, Q15788, P10415GPER1, MMP9, PRKACB, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, ITPR1, CALM1, CALM2, NCOA1, BCL2More
Bendazachsa04916Melanogenesis3.48E-036P0DP23, Q9UJU2, Q08828, P51828, P17252, P04628CALM1, LEF1, ADCY1, ADCY7, PRKCA, WNT1More
Bendazachsa04918Thyroid hormone synthesis3.50E-023P22694, P18848, Q14643PRKACB, ATF4, ITPR1More
Bendazachsa04920Adipocytokine signaling pathway2.75E-036P25963, Q06124, P33121, Q9Y478, Q04759, P01375NFKBIA, PTPN11, ACSL1, PRKAB1, PRKCQ, TNFMore
Bendazachsa04921Oxytocin signaling pathway7.73E-067Q15746, P0DP24, Q08828, P51828, P24844, Q96RR4, Q8WYR1MYLK, CALM2, ADCY1, ADCY7, MYL9, CAMKK2, PIK3R5More
Bendazachsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Bendazachsa04923Regulation of lipolysis in adipocytes2.89E-046Q08828, P51828, P07550, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, PIK3CB, IRS2, AKT2More
Bendazachsa04924Renin secretion9.20E-085P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Bendazachsa04925Aldosterone synthesis and secretion1.35E-047Q99941, P18848, Q08828, P51828, P0DP23, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM1, CAMK2D, ATP2B4More
Bendazachsa04926Relaxin signaling pathway2.97E-0511P31751, P25963, P42338, P62873, P63218, P50151, P18848, P49767, Q08828, P51828, P17252AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, ATF4, VEGFC, ADCY1, ADCY7, PRKCAMore
Bendazachsa04927Cortisol synthesis and secretion2.56E-055Q14643, P18848, Q08828, P51828, P22694ITPR1, ATF4, ADCY1, ADCY7, PRKACBMore
Bendazachsa04928Parathyroid hormone synthesis, secretion and action1.13E-056Q14643, P22694, P23771, P17252, P18848, P10415ITPR1, PRKACB, GATA3, PRKCA, ATF4, BCL2More
Bendazachsa04931Insulin resistance1.48E-022Q06124, Q9Y478PTPN11, PRKAB1More
Bendazachsa04932Non-alcoholic fatty liver disease1.69E-038P31751, O43521, P18848, O75460, P01584, P13073, P12074, O95298AKT2, BCL2L11, ATF4, ERN1, IL1B, COX4I1, COX6A1, NDUFC2More
Bendazachsa04933AGE-RAGE signaling pathway in diabetic complications2.76E-037P84022, Q13485, P42224, P42338, P49767, P17252, P19174SMAD3, SMAD4, STAT1, PIK3CB, VEGFC, PRKCA, PLCG1More
Bendazachsa04934Cushing syndrome6.88E-059Q14643, Q99941, P18848, Q08828, P51828, P22694, O15169, Q13557, P04628ITPR1, CREBL1, ATF4, ADCY1, ADCY7, PRKACB, AXIN1, CAMK2D, WNT1More
Bendazachsa04935Growth hormone synthesis, secretion and action1.88E-024Q08828, P51828, P18848, P31751ADCY1, ADCY7, ATF4, AKT2More
Bendazachsa04950Maturity onset diabetes of the young2.03E-021P35557GCKMore
Bendazachsa04962Vasopressin-regulated water reabsorption1.80E-022P62491, P46459RAB11A, NSFMore
Bendazachsa04964Proximal tubule bicarbonate reclamation2.17E-031P00918CA2More
Bendazachsa04966Collecting duct acid secretion2.17E-031P00918CA2More
Bendazachsa04970Salivary secretion7.84E-079P07550, Q08828, P51828, P22694, Q14643, P23634, P17252, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B4, PRKCA, CALM1, CAMPMore
Bendazachsa04971Gastric acid secretion9.27E-055Q08828, P51828, P15311, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM1, CAMK2DMore
Bendazachsa04972Pancreatic secretion1.51E-032Q08828, P62491ADCY1, RAB11AMore
Bendazachsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Bendazachsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Bendazachsa04976Bile secretion1.80E-036O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Bendazachsa05010Alzheimer disease3.34E-0414Q92542, O95298, P05496, P12074, Q00535, O75460, P0DP23, P01584, P18848, O15169, P31751, P05141, P45880, P28070NCSTN, NDUFC2, ATP5G1, COX6A1, CDK5, ERN1, CALM1, IL1B, ATF4, AXIN1, AKT2, SLC25A5, VDAC2, PSMB4More
Bendazachsa05012Parkinson disease2.12E-037P21796, P60604, P19174, P0DP23, Q71U36, Q13509, P68371VDAC1, UBE2G2, PLCG1, CALM1, TUBA1A, TUBB3, TUBB2CMore
Bendazachsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Bendazachsa05016Huntington disease5.79E-0410O95298, Q9GZM3, P24928, P30876, P62487, P52435, P05141, O75460, P28070, P55036NDUFC2, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, ERN1, PSMB4, PSMD4More
Bendazachsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Bendazachsa05020Prion disease1.81E-027P01584, P46531, P11142, P05496, P12074, P45880, Q99941IL1B, NOTCH1, HSPA8, ATP5G1, COX6A1, VDAC2, CREBL1More
Bendazachsa05022Pathways of neurodegeneration - multiple diseases1.67E-029O95298, Q8TEV9, O75460, P18848, P05141, Q00535, P01584, P0DP23, P28070NDUFC2, SMCR8, ERN1, ATF4, SLC25A5, CDK5, IL1B, CALM1, PSMB4More
Bendazachsa05032Morphine addiction9.51E-077P62873, P63218, P50151, Q13370, P48169, P17252, P43250GNB1, GNG5, GNG10, PDE3B, GABRA4, PRKCA, GRK6More
Bendazachsa05033Nicotine addiction2.43E-021P48169GABRA4More
Bendazachsa05034Alcoholism6.06E-0611Q13547, P0DP23, P62873, P63218, P50151, Q93077, P62807, Q93079, Q16778, O60814, P68431HDAC1, CALM1, GNB1, GNG5, GNG10, HIST1H2AC, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Bendazachsa05110Vibrio cholerae infection3.15E-023Q13488, P17252, P19174TCIRG1, PRKCA, PLCG1More
Bendazachsa05120Epithelial cell signaling in Helicobacter pylori infection8.10E-079Q16539, P25963, Q13488, P09341, P19875, P19174, P25024, P25025, P07948MAPK14, NFKBIA, TCIRG1, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, LYNMore
Bendazachsa05130Pathogenic Escherichia coli infection3.29E-039Q71U36, Q14247, O00501, P16333, Q13509, P68371, P25116, Q14344, P25963TUBA1A, CTTN, CLDN5, NCK1, TUBB3, TUBB2C, F2R, GNA13, NFKBIAMore
Bendazachsa05131Shigellosis3.34E-0211P01375, P25963, O00463, Q04759, Q9UDY8, Q9H1Y0, Q14643, Q12778, Q13315, P10415, Q96A32TNF, NFKBIA, TRAF5, PRKCQ, MALT1, ATG5, ITPR1, FOXO1, ATM, BCL2, MYLPFMore
Bendazachsa05132Salmonella infection2.72E-0620P51617, P25963, P01375, P08238, Q9UJU2, P01106, P42338, Q13546, Q13489, P10415, O75369, Q96A32, O60603, Q9BQS8, Q13561, O60282, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, LEF1, MYC, PIK3CB, RIPK1, BIRC3, BCL2, FLNB, MYLPF, TLR2, FYCO1, DCTN2, KIF5C, TUBA1A, TUBB3, TUBB2C, VPS41More
Bendazachsa05133Pertussis2.60E-042P0DP23, P0C0L4CALM1, C4AMore
Bendazachsa05134Legionellosis8.41E-057P01584, P25963, Q9NR31, P11215, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, HSPA8, CXCL1, CXCL2More
Bendazachsa05140Leishmaniasis8.55E-0814P13612, O75015, P14598, P11215, P42224, P13765, O60603, P25963, P01375, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, ITGAM, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Bendazachsa05143African trypanosomiasis1.14E-042P69905, P68871HBA2, HBBMore
Bendazachsa05144Malaria1.16E-047P60033, P69905, P68871, O60603, P01375, P35443, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Bendazachsa05145Toxoplasmosis2.20E-0514P51617, P25963, P01375, P10415, Q13489, P23458, P42224, P13765, P09917, Q8WYR1, Q13751, P0DMV8, P11142, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, JAK1, STAT1, HLA-DOB, ALOX5, PIK3R5, LAMB3, HSPA1A, HSPA8, TLR2More
Bendazachsa05146Amoebiasis1.24E-1012P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Bendazachsa05150Staphylococcus aureus infection2.37E-0610P0C0L4, P21462, O75015, P13646, Q14532, P16109, P59665, P59666, P12838, P49913C4A, FPR1, FCGR3B, KRT13, KRT32, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Bendazachsa05152Tuberculosis2.89E-0513Q13488, P0DP23, O75015, P48382, O60603, P01375, P10415, P13765, P01568, P49913, Q9UDY8, Q16539, P51617TCIRG1, CALM1, FCGR3B, RFX5, TLR2, TNF, BCL2, HLA-DOB, IFNA21, CAMP, MALT1, MAPK14, IRAK1More
Bendazachsa05161Hepatitis B2.33E-028P17252, P14780, P25963, P01375, P10415, P51617, O60603, Q14765PRKCA, MMP9, NFKBIA, TNF, BCL2, IRAK1, TLR2, STAT4More
Bendazachsa05162Measles2.19E-0413P01568, P25963, P23458, P42224, P14784, P07766, P42338, P0DMV8, P11142, P01584, Q13191, P67870, Q9NP90IFNA21, NFKBIA, JAK1, STAT1, IL2RB, CD3E, PIK3CB, HSPA1A, HSPA8, IL1B, CBLB, CSNK2B, RAB9BMore
Bendazachsa05163Human cytomegalovirus infection1.73E-1228P31751, P42338, P01375, P30511, P25963, P62873, P63218, P50151, Q14643, P0DP23, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P01106, P14778, P01584, P17252, Q13651, P25025, Q16539, P18848, P04637, O00463, P30101, P01568AKT2, PIK3CB, TNF, HLA-F, NFKBIA, GNB1, GNG5, GNG10, ITPR1, CALM1, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, MYC, IL1R1, IL1B, PRKCA, IL10RA, CXCR2, MAPK14, ATF4, TP53, TRAF5, PDIA3, IFNA21More
Bendazachsa05164Influenza A4.49E-025P31751, P01584, P23458, P05141, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, NXF1More
Bendazachsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Bendazachsa05167Kaposi sarcoma-associated herpesvirus infection4.28E-1117P01568, P42224, P25963, P42338, P40189, P62873, P62879, P63218, P50151, P19174, P16298, Q02750, P07948, P01106, P04141, P0DP23, P0CG47IFNA21, STAT1, NFKBIA, PIK3CB, IL6ST, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, MAP2K1, LYN, MYC, CSF2, CALM1, UBBMore
Bendazachsa05168Herpes simplex virus 1 infection2.37E-0819P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q13489, P30101, P42338, Q9Y2A4, Q13398, P51522, Q9HCX3, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF304, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Bendazachsa05169Epstein-Barr virus infection2.50E-0520P20023, P13765, P01106, Q13547, Q92769, O00463, P25963, Q16539, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, O60603, P07766, P09693, P20963CR2, HLA-DOB, MYC, HDAC1, HDAC2, TRAF5, NFKBIA, MAPK14, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, TLR2, CD3E, CD3G, CD247More
Bendazachsa05170Human immunodeficiency virus 1 infection1.19E-1128P42338, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, P01375, Q05397, P17252, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P23528, P07766, P10415, Q13619, Q93034, Q9Y6Q5, P20333PIK3CB, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, CFL1, CD3E, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Bendazachsa05171Coronavirus disease - COVID-193.30E-027P25963, P42224, P01568, P40189, P42338, P19174, P17252NFKBIA, STAT1, IFNA21, IL6ST, PIK3CB, PLCG1, PRKCAMore
Bendazachsa05200Pathways in cancer8.65E-1131Q13751, P42338, P08238, P42224, P25963, P19174, P01106, P17252, P43246, P84022, Q13485, P20585, Q13547, P10826, P14923, P30281, Q13489, P49767, P14921, P43657, P62873, P63218, P50151, Q14344, Q7LDG7, P78417, O75293, P0DP23, P01568, P14784, P40189LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, PRKCA, MSH2, SMAD3, SMAD4, MSH3, HDAC1, RARB, JUP, CCND3, BIRC3, VEGFC, ETS1, P2RY5, GNB1, GNG5, GNG10, GNA13, RASGRP2, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Bendazachsa05202Transcriptional misregulation in cancer2.25E-1222Q12778, Q15532, Q13315, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522FOXO1, SS18, ATM, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45AMore
Bendazachsa05203Viral carcinogenesis3.37E-0617Q12933, P23458, P42229, P42338, P06746, P07948, P27348, P29083, Q7KZF4, Q13547, Q15283, P12814, P25963, P62807, Q93079, Q16778, O60814TRAF2, JAK1, STAT5A, PIK3CB, POLB, LYN, YWHAQ, GTF2E1, SND1, HDAC1, RASA2, ACTN1, NFKBIA, HIST1H2BC, H2BC9, HIST2H2BE, H2BC12More
Bendazachsa05204Chemical carcinogenesis1.77E-044Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
Bendazachsa05205Proteoglycans in cancer4.93E-0311Q13009, Q12955, Q14643, O75369, P14780, P17252, O60603, P08069, P04628, Q13635, P08962TIAM1, ANK3, ITPR1, FLNB, MMP9, PRKCA, TLR2, IGF1R, WNT1, PTCH1, CD63More
Bendazachsa05206MicroRNAs in cancer4.00E-0413P30304, P09493, P15311, P21860, P01106, P42338, P61978, P46531, Q13547, P63279, P22105, P20827, P19174CDC25A, TPM1, VIL2, ERBB3, MYC, PIK3CB, HNRPK, NOTCH1, HDAC1, UBE2I, TNXB, EFNA1, PLCG1More
Bendazachsa05212Pancreatic cancer1.95E-058P42338, P31751, Q15311, P23458, P42224, P84022, Q13485, O75293PIK3CB, AKT2, RALBP1, JAK1, STAT1, SMAD3, SMAD4, GADD45BMore
Bendazachsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Bendazachsa05214Glioma1.27E-076P08069, P0DP23, P17252, P42338, P19174, O75293IGF1R, CALM1, PRKCA, PIK3CB, PLCG1, GADD45BMore
Bendazachsa05215Prostate cancer1.33E-021P08069IGF1RMore
Bendazachsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Bendazachsa05217Basal cell carcinoma2.83E-023Q13635, Q9UJU2, P24522PTCH1, LEF1, GADD45AMore
Bendazachsa05218Melanoma2.77E-034P08069, Q9NRA1, P42338, O75293IGF1R, PDGFC, PIK3CB, GADD45BMore
Bendazachsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Bendazachsa05220Chronic myeloid leukemia1.15E-037Q13547, P01106, Q13485, P25963, P84022, P42338, O75293HDAC1, MYC, SMAD4, NFKBIA, SMAD3, PIK3CB, GADD45BMore
Bendazachsa05222Small cell lung cancer9.25E-0410P10826, P42338, Q13751, Q13489, P10415, P25963, Q13077, O00463, P24522, O75293RARB, PIK3CB, LAMB3, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A, GADD45BMore
Bendazachsa05223Non-small cell lung cancer2.55E-056P17252, P42338, P19174, P10826, Q9HC35, O75293PRKCA, PIK3CB, PLCG1, RARB, EML4, GADD45BMore
Bendazachsa05224Breast cancer1.24E-025P08069, P49841, Q92837, P04637, P24522IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Bendazachsa05225Hepatocellular carcinoma1.33E-021P08069IGF1RMore
Bendazachsa05226Gastric cancer8.67E-034Q02750, O15169, P04628, P10826MAP2K1, AXIN1, WNT1, RARBMore
Bendazachsa05231Choline metabolism in cancer4.14E-0810P31751, P42338, Q9NRA1, Q9Y259, P19174, P23743, P49619, Q16760, O14986, P17252AKT2, PIK3CB, PDGFC, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PRKCAMore
Bendazachsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.88E-1115P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Bendazachsa05310Asthma9.09E-053P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Bendazachsa05320Autoimmune thyroid disease8.64E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Bendazachsa05321Inflammatory bowel disease1.20E-117O60603, P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Bendazachsa05322Systemic lupus erythematosus1.30E-0615O75015, P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P62807, Q16778, O60814, P68431, P12814, P05455FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1, SSBMore
Bendazachsa05323Rheumatoid arthritis1.60E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Bendazachsa05332Graft-versus-host disease2.48E-125P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Bendazachsa05340Primary immunodeficiency2.17E-044P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore
Bendazachsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Bendazachsa05414Dilated cardiomyopathy2.60E-033P54284, P09493, P26678CACNB3, TPM1, PLNMore
Bendazachsa05415Diabetic cardiomyopathy1.07E-026P17252, P14598, Q15080, Q16718, O14521, P04406PRKCA, NCF1, NCF4, NDUFA5, SDHD, GAPDHMore
Bendazachsa05418Fluid shear stress and atherosclerosis3.33E-0612Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Bendazac (SDC: 10.29)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
P27694RPA1Replication protein A 70 kDa DNANonebinding subunitPredicted00.22730.17560.27460.7395
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P42892ECE1EndothelinNoneconverting enzyme 1Predicted00.48530.092200.4269
Q9GZT9EGLN1Egl nine homolog 1Predicted00.58040.60610.25561.7581
P61586RHOATransforming protein RhoAPredicted00.35410.068911.3149
P15121AKR1B1AldoNoneketo reductase family 1 member B1Predicted10.56830.6290.2141.7562
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
Q9Y478PRKAB15'NoneAMPNoneactivated protein kinase subunit betaNone1Predicted10.14780.10880.55640.8479
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P00734F2ProthrombinPredicted10.09630.7070.49771.9598
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
Q13133NR1H3Oxysterols receptor LXRNonealphaPredicted00.01620.4390.20861.0947
P05164MPOMyeloperoxidasePredicted10.20350.53680.55021.7255
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P98170BIRC4E3 ubiquitinNoneprotein ligase XIAPPredicted00.29740.22980.791.3984
P05186ALPLAlkaline phosphatase, tissueNonenonspecific isozymePredicted00.30640.41430.19921.181
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
Q15722LTB4RLeukotriene B4 receptor 1Predicted00.06770.219900.4736
P04818TYMSThymidylate synthasePredicted10.45530.27060.18930.9582
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
Q13822ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Predicted00.1130.3050.00630.6729
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
P11766ADH5Alcohol dehydrogenase classNone3Predicted00.2650.13970.21460.6265
P11511CYP19A1AromatasePredicted00.815610.15882.5666
O95271TNKSPoly [ADPNoneribose] polymerase tankyraseNone1Predicted00.10170.222400.4957
P07195LDHBLNonelactate dehydrogenase B chainPredicted00.01670.17490.2310.5892
P10415BCL2Apoptosis regulator BclNone2Predicted10.03410.527112.0714
Q07817BCL2L1BclNone2Nonelike protein 1Predicted10.08720.434911.9134
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P21453S1PR1Sphingosine 1Nonephosphate receptor 1Predicted10.14340.38470.2211.0621
Q15788NCOA1Nuclear receptor coactivator 1Predicted00.43680.08280.31140.6954
Q16769QPCTGlutaminylNonepeptide cyclotransferasePredicted00.02450.241600.4954
Q8WUM9SLC20A1SodiumNonedependent phosphate transporter 1Predicted00.69560.02700.4018
Q08357SLC20A2SodiumNonedependent phosphate transporter 2Predicted00.08530.02700.0966
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
P30304CDC25AMNonephase inducer phosphatase 1Predicted00.17950.23470.42740.9865
P16109SELPPNoneselectinPredicted10.15230.07220.57330.7938
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
P40925MDH1Malate dehydrogenase, cytoplasmicPredicted00.35660.27460.24260.97
P08514ITGA2BIntegrin alphaNoneIIbPredicted10.07820.32480.7791.4677
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
P16083NQO2Ribosyldihydronicotinamide dehydrogenase [quinone]Predicted00.29580.313400.7747
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)