PharmaCoNets of Bacitracin (SPCN: 0.26 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Bacitracinhsa00310Lysine degradation2.88E-022Q9NVH6, O15047TMLHE, SETD1AMore
Bacitracinhsa00500Starch and sucrose metabolism2.88E-022O43451, P06737MGAM, PYGLMore
Bacitracinhsa00730Thiamine metabolism4.56E-032P05186, P24666ALPL, ACP1More
Bacitracinhsa01100Metabolic pathways4.89E-0317Q96DU7, Q08828, Q02153, O43286, O43451, P05186, P24666, Q86XP1, O60701, P33121, Q9UHK6, Q86VZ5, P57054, P06737, P05166, O15047, Q9NVH6ITPKC, ADCY1, GUCY1B3, B4GALT5, MGAM, ALPL, ACP1, DGKH, UGDH, ACSL1, AMACR, SGMS1, PIGP, PYGL, PCCB, SETD1A, TMLHEMore
Bacitracinhsa04012ErbB signaling pathway6.79E-034P21860, P49841, Q13557, O14944ERBB3, GSK3B, CAMK2D, EREGMore
Bacitracinhsa04020Calcium signaling pathway1.71E-036Q96DU7, Q08828, Q13557, P21860, Q93086, P63092ITPKC, ADCY1, CAMK2D, ERBB3, P2RX5, GNASMore
Bacitracinhsa04072Phospholipase D signaling pathway8.42E-035Q9UQC2, P25025, P63092, Q08828, Q86XP1GAB2, CXCR2, GNAS, ADCY1, DGKHMore
Bacitracinhsa04261Adrenergic signaling in cardiomyocytes2.86E-024P63092, Q08828, Q13557, Q16539GNAS, ADCY1, CAMK2D, MAPK14More
Bacitracinhsa04540Gap junction2.74E-023Q08828, Q02153, P63092ADCY1, GUCY1B3, GNASMore
Bacitracinhsa04611Platelet activation1.75E-024Q02153, Q16539, Q08828, P63092GUCY1B3, MAPK14, ADCY1, GNASMore
Bacitracinhsa04713Circadian entrainment6.79E-034Q13557, Q02153, Q08828, P63092CAMK2D, GUCY1B3, ADCY1, GNASMore
Bacitracinhsa04714Thermogenesis1.53E-025Q16539, P63092, Q08828, P51531, P33121MAPK14, GNAS, ADCY1, SMARCA2, ACSL1More
Bacitracinhsa04728Dopaminergic synapse3.19E-024P63092, P49841, Q16539, Q13557GNAS, GSK3B, MAPK14, CAMK2DMore
Bacitracinhsa04750Inflammatory mediator regulation of TRP channels8.14E-034P63092, Q08828, Q13557, Q16539GNAS, ADCY1, CAMK2D, MAPK14More
Bacitracinhsa04911Insulin secretion1.29E-023Q08828, P63092, Q13557ADCY1, GNAS, CAMK2DMore
Bacitracinhsa04912GnRH signaling pathway3.64E-034Q08828, Q13557, Q16539, P63092ADCY1, CAMK2D, MAPK14, GNASMore
Bacitracinhsa04916Melanogenesis2.87E-034Q13557, P63092, Q08828, P49841CAMK2D, GNAS, ADCY1, GSK3BMore
Bacitracinhsa04921Oxytocin signaling pathway1.75E-024Q08828, P63092, Q13557, Q02153ADCY1, GNAS, CAMK2D, GUCY1B3More
Bacitracinhsa04924Renin secretion4.69E-022P63092, Q02153GNAS, GUCY1B3More
Bacitracinhsa04925Aldosterone synthesis and secretion3.20E-023Q08828, P63092, Q13557ADCY1, GNAS, CAMK2DMore
Bacitracinhsa04926Relaxin signaling pathway2.55E-024P63092, Q08828, P37173, Q16539GNAS, ADCY1, TGFBR2, MAPK14More
Bacitracinhsa04934Cushing syndrome8.14E-034Q08828, P63092, P49841, Q13557ADCY1, GNAS, GSK3B, CAMK2DMore
Bacitracinhsa04935Growth hormone synthesis, secretion and action1.53E-024Q08828, P63092, P49841, Q16539ADCY1, GNAS, GSK3B, MAPK14More
Bacitracinhsa04970Salivary secretion1.60E-023P63092, Q08828, Q02153GNAS, ADCY1, GUCY1B3More
Bacitracinhsa04971Gastric acid secretion2.32E-023Q08828, P63092, Q13557ADCY1, GNAS, CAMK2DMore
Bacitracinhsa04976Bile secretion1.02E-023O43315, P63092, Q08828AQP9, GNAS, ADCY1More
Bacitracinhsa05142Chagas disease1.13E-024Q16539, P37173, P63092, Q08828MAPK14, TGFBR2, GNAS, ADCY1More
Bacitracinhsa05225Hepatocellular carcinoma3.91E-024P49841, Q92837, P37173, P51531GSK3B, FRAT1, TGFBR2, SMARCA2More
Bacitracinhsa05414Dilated cardiomyopathy4.79E-023P26012, P63092, Q08828ITGB8, GNAS, ADCY1More

Community members of Bacitracin (SDC: 0.08)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
O43847NRD1NardilysinPredicted00.43050.002300.2199
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)