PharmaCoNets of Avatrombopag (SPCN: 0.85 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Avatrombopaghsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Avatrombopaghsa04216Ferroptosis3.68E-022P04637, P02792TP53, FTLMore
Avatrombopaghsa04613Neutrophil extracellular trap formation1.23E-035P11215, Q13547, P58876, Q16778, O60814ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12More
Avatrombopaghsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Avatrombopaghsa05131Shigellosis4.06E-024Q16539, P68431, Q92974, P04637MAPK14, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ARHGEF2, TP53More
Avatrombopaghsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Avatrombopaghsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Avatrombopaghsa05212Pancreatic cancer4.73E-022P11233, P04637RALA, TP53More
Avatrombopaghsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Avatrombopaghsa05418Fluid shear stress and atherosclerosis3.73E-023Q16539, P04637, Q92974MAPK14, TP53, ARHGEF2More

Community members of Avatrombopag (SDC: 0.47)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P45844ABCG1ATPNonebinding cassette subNonefamily G member 1Predicted00.22050.002100.1144
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)