| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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| Aurothioglucose | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | | | Aurothioglucose | hsa00190 | Oxidative phosphorylation | 4.38E-02 | 4 | O95298, O15239, P12074, P05496 | NDUFC2, NDUFA1, COX6A1, ATP5G1 | More | | | Aurothioglucose | hsa00220 | Arginine biosynthesis | 2.21E-02 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Aurothioglucose | hsa00230 | Purine metabolism | 4.02E-02 | 2 | P31350, P21589 | RRM2, NT5E | More | | | Aurothioglucose | hsa00240 | Pyrimidine metabolism | 2.54E-04 | 3 | P31350, P21589, P04818 | RRM2, NT5E, TYMS | More | | | Aurothioglucose | hsa00250 | Alanine, aspartate and glutamate metabolism | 2.21E-02 | 2 | P49448, P15104 | GLUD2, GLUL | More | | | Aurothioglucose | hsa00500 | Starch and sucrose metabolism | 3.88E-02 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Aurothioglucose | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | | | Aurothioglucose | hsa00730 | Thiamine metabolism | 3.79E-02 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Aurothioglucose | hsa00910 | Nitrogen metabolism | 2.21E-02 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Aurothioglucose | hsa00970 | Aminoacyl-tRNA biosynthesis | 4.16E-02 | 2 | O95363, Q15046 | FARS2, KARS | More | | | Aurothioglucose | hsa01523 | Antifolate resistance | 6.06E-03 | 2 | Q92820, P04818 | GGH, TYMS | More | | | Aurothioglucose | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Aurothioglucose | hsa03010 | Ribosome | 4.16E-02 | 2 | P46777, P50914 | RPL5, RPL14 | More | | | Aurothioglucose | hsa03020 | RNA polymerase | 4.11E-04 | 4 | P30876, P24928, P62487, Q9Y535 | POLR2B, POLR2A, POLR2G, POLR3H | More | | | Aurothioglucose | hsa03060 | Protein export | 2.83E-02 | 2 | P37108, Q15005 | SRP14, SPCS2 | More | | | Aurothioglucose | hsa04020 | Calcium signaling pathway | 1.64E-02 | 5 | Q96DU7, Q08828, Q13557, P21860, P0DP23 | ITPKC, ADCY1, CAMK2D, ERBB3, CALM1 | More | | | Aurothioglucose | hsa04064 | NF-kappa B signaling pathway | 9.26E-05 | 13 | P10415, O00463, P01584, P01375, Q04759, Q13077, Q16548, Q8WV28, P63279, P24522, Q8NHW4, P09341, Q9NQC7 | BCL2, TRAF5, IL1B, TNF, PRKCQ, TRAF1, BCL2A1, BLNK, UBE2I, GADD45A, CCL4L2, CXCL1, CYLD | More | | | Aurothioglucose | hsa04071 | Sphingolipid signaling pathway | 2.06E-02 | 7 | Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2 | EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2 | More | | | Aurothioglucose | hsa04080 | Neuroactive ligand-receptor interaction | 2.54E-02 | 7 | P08311, Q15722, Q9H228, P21462, P21730, Q16581, P35318 | CTSG, LTB4R, EDG8, FPR1, C5AR1, C3AR1, ADM | More | | | Aurothioglucose | hsa04110 | Cell cycle | 2.34E-02 | 3 | P06493, O60566, P33981 | CDK1, BUB1B, TTK | More | | | Aurothioglucose | hsa04115 | p53 signaling pathway | 3.34E-02 | 2 | P31350, P06493 | RRM2, CDK1 | More | | | Aurothioglucose | hsa04142 | Lysosome | 1.13E-02 | 6 | P22304, P38571, Q13510, P61916, Q04900, Q9Y227 | IDS, LIPA, ASAH1, NPC2, CD164, ENTPD4 | More | | | Aurothioglucose | hsa04217 | Necroptosis | 3.67E-02 | 5 | P23458, Q9NQC7, P07900, P01584, O75351 | JAK1, CYLD, HSP90AA1, IL1B, VPS4B | More | | | Aurothioglucose | hsa04218 | Cellular senescence | 2.19E-02 | 6 | P01106, Q9H422, P42338, Q16539, P24522, P30304 | MYC, HIPK3, PIK3CB, MAPK14, GADD45A, CDC25A | More | | | Aurothioglucose | hsa04270 | Vascular smooth muscle contraction | 4.38E-02 | 4 | P0DP23, Q08828, P35579, P35318 | CALM1, ADCY1, MYH9, ADM | More | | | Aurothioglucose | hsa04340 | Hedgehog signaling pathway | 1.43E-02 | 4 | P49841, P22694, Q13635, P10415 | GSK3B, PRKACB, PTCH1, BCL2 | More | | | Aurothioglucose | hsa04370 | VEGF signaling pathway | 4.16E-02 | 2 | P42338, Q16539 | PIK3CB, MAPK14 | More | | | Aurothioglucose | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | | | Aurothioglucose | hsa04613 | Neutrophil extracellular trap formation | 1.37E-02 | 12 | O60603, P05164, P08246, Q9UM07, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539 | TLR2, MPO, ELA2, PADI4, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14 | More | | | Aurothioglucose | hsa04620 | Toll-like receptor signaling pathway | 2.22E-04 | 3 | P01584, P45985, Q8NHW4 | IL1B, MAP2K4, CCL4L2 | More | | | Aurothioglucose | hsa04621 | NOD-like receptor signaling pathway | 2.64E-02 | 10 | Q16539, Q14643, P10599, Q9H1Y0, P43490, O00463, P10415, P01375, P09341, P12838 | MAPK14, ITPR1, TXN, ATG5, PBEF1, TRAF5, BCL2, TNF, CXCL1, DEFA4 | More | | | Aurothioglucose | hsa04623 | Cytosolic DNA-sensing pathway | 6.29E-06 | 3 | P01584, Q9Y535, Q8NHW4 | IL1B, POLR3H, CCL4L2 | More | | | Aurothioglucose | hsa04657 | IL-17 signaling pathway | 1.28E-02 | 7 | O00463, Q16539, P49841, P09341, P14780, P80188, P01375 | TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF | More | | | Aurothioglucose | hsa04658 | Th1 and Th2 cell differentiation | 3.21E-03 | 9 | Q04759, P20963, P09693, Q16539, Q14765, P42226, P23771, Q9UL17, P13765 | PRKCQ, CD247, CD3G, MAPK14, STAT4, STAT6, GATA3, TBX21, HLA-DOB | More | | | Aurothioglucose | hsa04659 | Th17 cell differentiation | 3.33E-03 | 12 | Q04759, Q16539, P01730, P06239, P42226, P13765, P14778, Q9UL17, P23771, P07766, P09693, P20963 | PRKCQ, MAPK14, CD4, LCK, STAT6, HLA-DOB, IL1R1, TBX21, GATA3, CD3E, CD3G, CD247 | More | | | Aurothioglucose | hsa04660 | T cell receptor signaling pathway | 1.07E-02 | 9 | P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q16539, P49841 | TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, MAPK14, GSK3B | More | | | Aurothioglucose | hsa04724 | Glutamatergic synapse | 1.17E-02 | 4 | P48058, P43003, P50151, P15104 | GRIA4, SLC1A3, GNG10, GLUL | More | | | Aurothioglucose | hsa04750 | Inflammatory mediator regulation of TRP channels | 1.25E-02 | 4 | P01584, Q08828, Q13557, P0DP23 | IL1B, ADCY1, CAMK2D, CALM1 | More | | | Aurothioglucose | hsa04915 | Estrogen signaling pathway | 6.80E-03 | 5 | P51828, P07900, P0DMV8, P0DP23, Q15788 | ADCY7, HSP90AA1, HSPA1A, CALM1, NCOA1 | More | | | Aurothioglucose | hsa04916 | Melanogenesis | 3.82E-02 | 3 | Q13557, P0DP23, Q08828 | CAMK2D, CALM1, ADCY1 | More | | | Aurothioglucose | hsa04921 | Oxytocin signaling pathway | 4.38E-02 | 4 | P0DP23, Q08828, Q13557, Q96RR4 | CALM1, ADCY1, CAMK2D, CAMKK2 | More | | | Aurothioglucose | hsa04932 | Non-alcoholic fatty liver disease | 4.28E-03 | 6 | O43521, O75460, P01584, P12074, O15239, O95298 | BCL2L11, ERN1, IL1B, COX6A1, NDUFA1, NDUFC2 | More | | | Aurothioglucose | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | | | Aurothioglucose | hsa04966 | Collecting duct acid secretion | 4.93E-02 | 1 | P00918 | CA2 | More | | | Aurothioglucose | hsa04971 | Gastric acid secretion | 1.74E-03 | 5 | Q08828, P51828, P15311, P0DP23, Q13557 | ADCY1, ADCY7, VIL2, CALM1, CAMK2D | More | | | Aurothioglucose | hsa04973 | Carbohydrate digestion and absorption | 7.81E-03 | 2 | O43451, P42338 | MGAM, PIK3CB | More | | | Aurothioglucose | hsa04979 | Cholesterol metabolism | 6.61E-03 | 3 | Q5SW96, P38571, P61916 | LDLRAP1, LIPA, NPC2 | More | | | Aurothioglucose | hsa05010 | Alzheimer disease | 3.88E-02 | 8 | O15239, O95298, P05496, P12074, Q00535, O75460, P0DP23, P01584 | NDUFA1, NDUFC2, ATP5G1, COX6A1, CDK5, ERN1, CALM1, IL1B | More | | | Aurothioglucose | hsa05012 | Parkinson disease | 8.37E-03 | 8 | P62987, O15239, O95298, P12074, P05496, O75460, P0DP23, Q13557 | UBA52, NDUFA1, NDUFC2, COX6A1, ATP5G1, ERN1, CALM1, CAMK2D | More | | | Aurothioglucose | hsa05016 | Huntington disease | 4.56E-02 | 7 | O15239, O95298, P12074, P05496, P24928, P62487, O75460 | NDUFA1, NDUFC2, COX6A1, ATP5G1, POLR2A, POLR2G, ERN1 | More | | | Aurothioglucose | hsa05022 | Pathways of neurodegeneration - multiple diseases | 3.63E-03 | 11 | O15239, O95298, P12074, P05496, Q8TEV9, O75460, Q00535, P01584, P0DP23, Q13557, P62987 | NDUFA1, NDUFC2, COX6A1, ATP5G1, SMCR8, ERN1, CDK5, IL1B, CALM1, CAMK2D, UBA52 | More | | | Aurothioglucose | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | | | Aurothioglucose | hsa05135 | Yersinia infection | 4.60E-02 | 4 | P06239, Q16539, P42338, P01730 | LCK, MAPK14, PIK3CB, CD4 | More | | | Aurothioglucose | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Aurothioglucose | hsa05144 | Malaria | 3.09E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Aurothioglucose | hsa05145 | Toxoplasmosis | 3.96E-02 | 2 | P28068, Q16787 | HLA-DMB, LAMA3 | More | | | Aurothioglucose | hsa05150 | Staphylococcus aureus infection | 4.37E-02 | 6 | P21730, P21462, O75015, P13765, Q16581, P12838 | C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, DEFA4 | More | | | Aurothioglucose | hsa05162 | Measles | 8.38E-03 | 4 | P23458, P0DMV8, P01584, Q9NP90 | JAK1, HSPA1A, IL1B, RAB9B | More | | | Aurothioglucose | hsa05163 | Human cytomegalovirus infection | 1.37E-03 | 11 | P42338, P50151, P0DP23, Q8NHW4, P51828, P23458, P01106, P14778, P01584, Q13651, Q16539 | PIK3CB, GNG10, CALM1, CCL4L2, ADCY7, JAK1, MYC, IL1R1, IL1B, IL10RA, MAPK14 | More | | | Aurothioglucose | hsa05165 | Human papillomavirus infection | 2.01E-02 | 3 | Q16787, Q02930, Q13315 | LAMA3, CREB5, ATM | More | | | Aurothioglucose | hsa05166 | Human T-cell leukemia virus 1 infection | 2.41E-03 | 12 | P01106, Q02930, O60566, P14778, P27930, P07766, P42338, P28068, P42773, P06239, Q13315, P01730 | MYC, CREB5, BUB1B, IL1R1, IL1R2, CD3E, PIK3CB, HLA-DMB, CDKN2C, LCK, ATM, CD4 | More | | | Aurothioglucose | hsa05169 | Epstein-Barr virus infection | 4.32E-02 | 11 | P13765, O00463, P16070, P10415, Q16539, P24522, Q8WV28, P01375, O60603, P09693, P20963 | HLA-DOB, TRAF5, CD44, BCL2, MAPK14, GADD45A, BLNK, TNF, TLR2, CD3G, CD247 | More | | | Aurothioglucose | hsa05202 | Transcriptional misregulation in cancer | 8.07E-04 | 14 | Q15532, P14780, P27930, Q16548, Q13077, Q15652, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P24522 | SS18, MMP9, IL1R2, BCL2A1, TRAF1, JMJD1C, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, GADD45A | More | | | Aurothioglucose | hsa05213 | Endometrial cancer | 3.83E-02 | 3 | P01106, P42338, P24522 | MYC, PIK3CB, GADD45A | More | | | Aurothioglucose | hsa05217 | Basal cell carcinoma | 1.43E-02 | 4 | Q13635, P49841, Q9UJU2, P24522 | PTCH1, GSK3B, LEF1, GADD45A | More | | | Aurothioglucose | hsa05224 | Breast cancer | 1.64E-02 | 4 | P42338, P01106, Q92837, P24522 | PIK3CB, MYC, FRAT1, GADD45A | More | | | Aurothioglucose | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1.28E-02 | 5 | P42338, P07766, P06239, Q16539, P01730 | PIK3CB, CD3E, LCK, MAPK14, CD4 | More | | | Aurothioglucose | hsa05321 | Inflammatory bowel disease | 7.62E-04 | 7 | O60603, P01375, P13765, Q14765, Q9UL17, P42226, P23771 | TLR2, TNF, HLA-DOB, STAT4, TBX21, STAT6, GATA3 | More | | | Aurothioglucose | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | | | Aurothioglucose | hsa05415 | Diabetic cardiomyopathy | 4.22E-02 | 5 | O15239, O95298, P05496, P12074, Q13557 | NDUFA1, NDUFC2, ATP5G1, COX6A1, CAMK2D | More | | | Aurothioglucose | hsa05418 | Fluid shear stress and atherosclerosis | 2.60E-02 | 5 | Q16539, P42338, P10599, P14778, P27930 | MAPK14, PIK3CB, TXN, IL1R1, IL1R2 | More | |
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