PharmaCoNets of Atazanavir (SPCN: 4.86 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Atazanavirhsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Atazanavirhsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Atazanavirhsa00520Amino sugar and nucleotide sugar metabolism2.24E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Atazanavirhsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Atazanavirhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Atazanavirhsa03013RNA transport2.99E-024P38919, P37198, P35658, P55884EIF4A3, NUP62, NUP214, EIF3BMore
Atazanavirhsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Atazanavirhsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Atazanavirhsa04330Notch signaling pathway2.77E-022Q92542, P49768NCSTN, PSEN1More
Atazanavirhsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Atazanavirhsa04610Complement and coagulation cascades3.16E-032P00734, P0C0L4F2, C4AMore
Atazanavirhsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Atazanavirhsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Atazanavirhsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Atazanavirhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Atazanavirhsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Atazanavirhsa05133Pertussis2.24E-022P0DP23, P0C0L4CALM1, C4AMore
Atazanavirhsa05143African trypanosomiasis4.81E-022P69905, P68871HBA2, HBBMore

Community members of Atazanavir (SDC: 2.88)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P49768PSEN1PresenilinNone1Predicted10.26770.65990.33081.7845
P00734F2ProthrombinPredicted10.09630.7070.49771.9598
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)