PharmaCoNets of Apalutamide (SPCN: 79.17 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Apalutamidehsa00030Pentose phosphate pathway1.69E-022P60891, P37837PRPS1, TALDO1More
Apalutamidehsa00062Fatty acid elongation3.94E-021Q9H5J4ELOVL6More
Apalutamidehsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Apalutamidehsa00220Arginine biosynthesis1.21E-021P15104GLULMore
Apalutamidehsa00250Alanine, aspartate and glutamate metabolism2.42E-021P15104GLULMore
Apalutamidehsa00380Tryptophan metabolism4.14E-021Q16613AANATMore
Apalutamidehsa00500Starch and sucrose metabolism1.33E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Apalutamidehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Apalutamidehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Apalutamidehsa00730Thiamine metabolism2.43E-032P05186, P24666ALPL, ACP1More
Apalutamidehsa00830Retinol metabolism2.20E-024P00325, P11766, Q9BPW9, O75911ADH1B, ADH5, DHRS9, DHRS3More
Apalutamidehsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Apalutamidehsa00910Nitrogen metabolism2.42E-021P15104GLULMore
Apalutamidehsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Apalutamidehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Apalutamidehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Apalutamidehsa01040Biosynthesis of unsaturated fatty acids2.13E-032P22307, Q9H5J4SCP2, ELOVL6More
Apalutamidehsa01100Metabolic pathways4.43E-0223Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Apalutamidehsa01212Fatty acid metabolism2.13E-032Q9H5J4, P22307ELOVL6, SCP2More
Apalutamidehsa01230Biosynthesis of amino acids1.90E-034P60891, Q99707, P15104, P37837PRPS1, MTR, GLUL, TALDO1More
Apalutamidehsa01523Antifolate resistance1.67E-033Q92820, P04818, P18054GGH, TYMS, ALOX12More
Apalutamidehsa03008Ribosome biogenesis in eukaryotes2.40E-035P19784, P67870, O14980, O60832, Q9BVP2CSNK2A2, CSNK2B, XPO1, DKC1, GNL3More
Apalutamidehsa03013RNA transport3.08E-0513O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, P23588, Q9Y6A5XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, EIF4B, TACC3More
Apalutamidehsa03050Proteasome1.40E-021P55036PSMD4More
Apalutamidehsa03320PPAR signaling pathway4.55E-022O00767, Q02318SCD, CYP27A1More
Apalutamidehsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Apalutamidehsa04024cAMP signaling pathway3.37E-023P63092, P26678, P61586GNAS, PLN, RHOAMore
Apalutamidehsa04061Viral protein interaction with cytokine and cytokine receptor4.68E-037P09341, P19875, P25024, P02775, P25025, Q13651, P14784CXCL1, CXCL2, CXCR1, PPBP, CXCR2, IL10RA, IL2RBMore
Apalutamidehsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Apalutamidehsa04064NF-kappa B signaling pathway1.46E-0821P10415, Q13489, P25963, P51617, O00463, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q8WV28, Q13315, P24522, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, BLNK, ATM, GADD45A, CXCL1, CXCL2, LTB, CYLDMore
Apalutamidehsa04071Sphingolipid signaling pathway6.14E-049P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Apalutamidehsa04072Phospholipase D signaling pathway5.37E-038P42338, P61586, P43657, P25024, P25025, P19174, O14986, P63092PIK3CB, RHOA, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNASMore
Apalutamidehsa04080Neuroactive ligand-receptor interaction9.45E-049P08311, Q15722, P21453, Q9H228, O00398, P21462, P21730, Q16581, P35318CTSG, LTB4R, S1PR1, EDG8, P2RY10, FPR1, C5AR1, C3AR1, ADMMore
Apalutamidehsa04110Cell cycle6.80E-036P06493, O75293, P30304, P33981, P42773, P01106CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Apalutamidehsa04115p53 signaling pathway3.57E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Apalutamidehsa04120Ubiquitin mediated proteolysis6.89E-035Q14145, Q13042, Q13191, Q15751, Q7Z6Z7KEAP1, CDC16, CBLB, HERC1, HUWE1More
Apalutamidehsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Apalutamidehsa04137Mitophagy - animal2.52E-022P19784, P67870CSNK2A2, CSNK2BMore
Apalutamidehsa04142Lysosome2.64E-022Q99437, P25774ATP6V0B, CTSSMore
Apalutamidehsa04145Phagosome7.50E-0310Q15080, P14598, Q13509, Q13488, Q99437, P05164, O60603, P35443, P13765, P25774NCF4, NCF1, TUBB3, TCIRG1, ATP6V0B, MPO, TLR2, THBS4, HLA-DOB, CTSSMore
Apalutamidehsa04210Apoptosis1.52E-029Q13315, P10415, Q13489, P25963, P01375, P24522, Q16548, Q13077, Q14643ATM, BCL2, BIRC3, NFKBIA, TNF, GADD45A, BCL2A1, TRAF1, ITPR1More
Apalutamidehsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Apalutamidehsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Apalutamidehsa04310Wnt signaling pathway4.17E-033P61586, P19784, P67870RHOA, CSNK2A2, CSNK2BMore
Apalutamidehsa04340Hedgehog signaling pathway1.43E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Apalutamidehsa04380Osteoclast differentiation2.05E-0312Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P01584, P14778, O75015, Q8WV28, P01375, Q15080, P78324CYLD, GAB2, MAPK14, JAK1, LCK, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, SIRPAMore
Apalutamidehsa04510Focal adhesion4.07E-023O14986, P61586, Q16363PIP5K1B, RHOA, LAMA4More
Apalutamidehsa04520Adherens junction1.38E-043P19784, P67870, P61586CSNK2A2, CSNK2B, RHOAMore
Apalutamidehsa04530Tight junction2.45E-036Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Apalutamidehsa04613Neutrophil extracellular trap formation1.67E-0623P17252, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Apalutamidehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Apalutamidehsa04621NOD-like receptor signaling pathway7.04E-0516Q16539, Q14643, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P09341, P49913, P59665, P59666, P12838MAPK14, ITPR1, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Apalutamidehsa04625C-type lectin receptor signaling pathway8.11E-039Q9ULY5, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P0DP24, Q16539CLEC4E, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, CALM2, MAPK14More
Apalutamidehsa04640Hematopoietic cell lineage4.59E-0416P13612, P21926, P14778, P27930, P11215, P15144, P11836, P25063, P07766, P09693, P01732, P01730, P09564, P13765, P01375, P01584ITGA4, CD9, IL1R1, IL1R2, ITGAM, ANPEP, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOB, TNF, IL1BMore
Apalutamidehsa04650Natural killer cell mediated cytotoxicity4.85E-0413P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, O75015, P26717, P26715PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Apalutamidehsa04657IL-17 signaling pathway9.60E-058O00463, Q16539, P49841, P09341, P14780, P80188, P01375, P01584TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF, IL1BMore
Apalutamidehsa04658Th1 and Th2 cell differentiation3.58E-0715Q04759, P07766, P20963, P09693, Q16539, P19174, P06239, Q14765, P42226, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, STAT4, STAT6, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Apalutamidehsa04659Th17 cell differentiation1.46E-0515Q04759, Q16539, P19174, P06239, P42226, P14784, P13765, P14778, Q9UL17, P23771, P01584, P07766, P09693, P20963, P23458PRKCQ, MAPK14, PLCG1, LCK, STAT6, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, IL1B, CD3E, CD3G, CD247, JAK1More
Apalutamidehsa04660T cell receptor signaling pathway1.16E-0617P01375, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Apalutamidehsa04668TNF signaling pathway2.59E-027P01375, O00463, Q13489, P25963, P20749, Q13077, P14780TNF, TRAF5, BIRC3, NFKBIA, BCL3, TRAF1, MMP9More
Apalutamidehsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Apalutamidehsa04713Circadian entrainment4.94E-022P62873, P63092GNB1, GNASMore
Apalutamidehsa04723Retrograde endocannabinoid signaling4.94E-022P48169, P62873GABRA4, GNB1More
Apalutamidehsa04724Glutamatergic synapse3.65E-022P63092, P62873GNAS, GNB1More
Apalutamidehsa04726Serotonergic synapse2.52E-022P63092, P62873GNAS, GNB1More
Apalutamidehsa04750Inflammatory mediator regulation of TRP channels3.14E-0411P14778, P01584, P51828, P22694, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24IL1R1, IL1B, ADCY7, PRKACB, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2More
Apalutamidehsa04912GnRH signaling pathway4.33E-026P51828, Q16539, Q9Y6R4, Q14643, P0DP24, P22694ADCY7, MAPK14, MAP3K4, ITPR1, CALM2, PRKACBMore
Apalutamidehsa04920Adipocytokine signaling pathway4.49E-024P25963, P33121, Q04759, P01375NFKBIA, ACSL1, PRKCQ, TNFMore
Apalutamidehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Apalutamidehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Apalutamidehsa04970Salivary secretion4.49E-024P22694, Q14643, P17252, P49913PRKACB, ITPR1, PRKCA, CAMPMore
Apalutamidehsa04972Pancreatic secretion3.65E-022P63092, P61586GNAS, RHOAMore
Apalutamidehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Apalutamidehsa05032Morphine addiction9.04E-055P62873, P48169, P78334, P63092, P32298GNB1, GABRA4, GABRE, GNAS, GRK4More
Apalutamidehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Apalutamidehsa05110Vibrio cholerae infection4.78E-021Q99437ATP6V0BMore
Apalutamidehsa05120Epithelial cell signaling in Helicobacter pylori infection1.96E-046Q16539, P09341, P19875, P19174, P25024, P25025MAPK14, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Apalutamidehsa05131Shigellosis3.34E-0211P01375, P25963, O00463, Q04759, Q9UDY8, Q9H1Y0, Q14643, Q12778, Q13315, P10415, Q96A32TNF, NFKBIA, TRAF5, PRKCQ, MALT1, ATG5, ITPR1, FOXO1, ATM, BCL2, MYLPFMore
Apalutamidehsa05132Salmonella infection2.98E-0211P51617, P25963, P01375, Q9UJU2, Q13489, P10415, Q96A32, O60603, Q9BQS8, Q13561, Q13509IRAK1, NFKBIA, TNF, LEF1, BIRC3, BCL2, MYLPF, TLR2, FYCO1, DCTN2, TUBB3More
Apalutamidehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Apalutamidehsa05140Leishmaniasis8.01E-0513P13612, O75015, P14598, P23458, P13765, O60603, P25963, P01375, P01584, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, JAK1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, MARCKSL1, MAPK14, IRAK1, NCF4More
Apalutamidehsa05142Chagas disease2.26E-023P01375, P30679, P48023TNF, GNA15, FASLGMore
Apalutamidehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Apalutamidehsa05144Malaria2.43E-026P60033, O60603, P01375, P35443, P01584, P26718CD81, TLR2, TNF, THBS4, IL1B, KLRK1More
Apalutamidehsa05145Toxoplasmosis3.07E-027P51617, P25963, P01375, P10415, Q13489, P13765, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, HLA-DOB, TLR2More
Apalutamidehsa05146Amoebiasis2.17E-0513P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Apalutamidehsa05150Staphylococcus aureus infection3.62E-038P21730, P21462, O75015, P13765, Q16581, P59665, P59666, P12838C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, DEFA1; DEFA1B, DEFA3, DEFA4More
Apalutamidehsa05152Tuberculosis9.13E-0311Q13488, Q99437, P48382, O60603, P01375, P10415, P13765, P25774, P49913, Q9UDY8, P51617TCIRG1, ATP6V0B, RFX5, TLR2, TNF, BCL2, HLA-DOB, CTSS, CAMP, MALT1, IRAK1More
Apalutamidehsa05160Hepatitis C4.55E-023O00501, P29728, P01106CLDN5, OAS2, MYCMore
Apalutamidehsa05161Hepatitis B2.33E-028P17252, P14780, P25963, P01375, P10415, P51617, O60603, Q14765PRKCA, MMP9, NFKBIA, TNF, BCL2, IRAK1, TLR2, STAT4More
Apalutamidehsa05163Human cytomegalovirus infection4.65E-0311P62873, Q14643, P61586, P49841, P14778, P25025, Q16539, P63092, P04637, O00463, P61769GNB1, ITPR1, RHOA, GSK3B, IL1R1, CXCR2, MAPK14, GNAS, TP53, TRAF5, B2MMore
Apalutamidehsa05169Epstein-Barr virus infection4.32E-0211P13765, O00463, P16070, P10415, Q16539, P24522, Q8WV28, P01375, O60603, P09693, P20963HLA-DOB, TRAF5, CD44, BCL2, MAPK14, GADD45A, BLNK, TNF, TLR2, CD3G, CD247More
Apalutamidehsa05170Human immunodeficiency virus 1 infection1.06E-0313P01375, P17252, O00463, Q14643, P51617, P25963, O60603, Q13315, O95067, P10415, Q13619, Q93034, Q9Y6Q5TNF, PRKCA, TRAF5, ITPR1, IRAK1, NFKBIA, TLR2, ATM, CCNB2, BCL2, CUL4A, CUL5, AP1M2More
Apalutamidehsa05171Coronavirus disease - COVID-194.47E-022Q9UHA3, O14786RSL24D1, NRP1More
Apalutamidehsa05202Transcriptional misregulation in cancer2.80E-0822Q12778, Q15532, Q13315, P17844, P14780, P27930, P14923, Q16548, Q13489, Q13077, Q15652, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, DDX5, MMP9, IL1R2, JUP, BCL2A1, BIRC3, TRAF1, JMJD1C, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Apalutamidehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Apalutamidehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Apalutamidehsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Apalutamidehsa05217Basal cell carcinoma1.30E-034Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Apalutamidehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Apalutamidehsa05222Small cell lung cancer2.79E-026Q13489, P10415, P25963, Q13077, O00463, P24522BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45AMore
Apalutamidehsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
Apalutamidehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Apalutamidehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.52E-0513P42338, O95267, P19174, P07766, P20963, P09693, P06239, P23458, O60603, Q04759, Q16539, Q9HC35, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, JAK1, TLR2, PRKCQ, MAPK14, EML4, CD4More
Apalutamidehsa05310Asthma3.88E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Apalutamidehsa05321Inflammatory bowel disease1.51E-068O60603, P01375, P13765, Q14765, Q9UL17, P42226, P23771, P01584TLR2, TNF, HLA-DOB, STAT4, TBX21, STAT6, GATA3, IL1BMore
Apalutamidehsa05322Systemic lupus erythematosus2.09E-0412P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P62807, O60814, P68431, P05455ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SSBMore
Apalutamidehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Apalutamidehsa05332Graft-versus-host disease8.44E-046P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Apalutamidehsa05340Primary immunodeficiency1.28E-034P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore
Apalutamidehsa05418Fluid shear stress and atherosclerosis2.62E-026Q16539, P10599, P14780, P04637, P14778, P27930MAPK14, TXN, MMP9, TP53, IL1R1, IL1R2More

Community members of Apalutamide (SDC: 6.03)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P48169GABRA4GammaNoneaminobutyric acid receptor subunit alphaNone4Reported00.32530.5650.15791.4506
P28472GABRB3GammaNoneaminobutyric acid receptor subunit betaNone3Reported00.15590.43870.16951.1248
P78334GABREGammaNoneaminobutyric acid receptor subunit epsilonReported00.13940.40970.15791.0469
P25774CTSSCathepsin SPredicted00.31850.49320.51681.6625
P06737PYGLGlycogen phosphorylase, liver formPredicted00.37330.22110.31690.9457
O00767SCDStearoylNoneCoA desaturasePredicted10.16860.1870.19970.6581
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
Q9H5J4ELOVL6Elongation of very long chain fatty acids protein 6Predicted00.07880.03270.16660.2713
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)