PharmaCoNets of Amprenavir (SPCN: 3.06 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Amprenavirhsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Amprenavirhsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Amprenavirhsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Amprenavirhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Amprenavirhsa03020RNA polymerase9.86E-072Q9GZM3, P52435POLR2J2, POLR2JMore
Amprenavirhsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Amprenavirhsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Amprenavirhsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Amprenavirhsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Amprenavirhsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Amprenavirhsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Amprenavirhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Amprenavirhsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Amprenavirhsa05016Huntington disease2.46E-053Q9GZM3, P52435, Q9NYC9POLR2J2, POLR2J, DNAH9More
Amprenavirhsa05100Bacterial invasion of epithelial cells4.50E-021Q92529SHC3More
Fosamprenavirhsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Fosamprenavirhsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Fosamprenavirhsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Fosamprenavirhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Fosamprenavirhsa03020RNA polymerase9.86E-072Q9GZM3, P52435POLR2J2, POLR2JMore
Fosamprenavirhsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Fosamprenavirhsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Fosamprenavirhsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Fosamprenavirhsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Fosamprenavirhsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Fosamprenavirhsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Fosamprenavirhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Fosamprenavirhsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Fosamprenavirhsa05016Huntington disease2.46E-053Q9GZM3, P52435, Q9NYC9POLR2J2, POLR2J, DNAH9More
Fosamprenavirhsa05100Bacterial invasion of epithelial cells4.50E-021Q92529SHC3More

Community members of Amprenavir (SDC: 2.03)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P22001KCNA3Potassium voltageNonegated channel subfamily A member 3Predicted10.13960.505501.0809
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)