PharmaCoNets of Ampicillin (SPCN: 4.98 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Ampicillinhsa00030Pentose phosphate pathway8.97E-031P11413G6PDMore
Ampicillinhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Ampicillinhsa00480Glutathione metabolism1.35E-021P11413G6PDMore
Ampicillinhsa00500Starch and sucrose metabolism2.67E-021P35573AGLMore
Ampicillinhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Ampicillinhsa00785Lipoic acid metabolism4.57E-021Q9Y234LIPT1More
Ampicillinhsa00920Sulfur metabolism8.89E-031Q16762TSTMore
Ampicillinhsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Ampicillinhsa01200Carbon metabolism2.91E-021P11413G6PDMore
Ampicillinhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Ampicillinhsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Ampicillinhsa04114Oocyte meiosis3.27E-023Q9UJX4, P30260, Q16539ANAPC5, CDC27, MAPK14More
Ampicillinhsa04122Sulfur relay system8.89E-031Q16762TSTMore
Ampicillinhsa04210Apoptosis4.31E-024P04637, P24522, P43234, P42575TP53, GADD45A, CTSO, CASP2More
Ampicillinhsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Ampicillinhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Ampicillinhsa04614Renin-angiotensin system9.97E-042P50052, P10619AGTR2, CTSAMore
Ampicillinhsa04914Progesterone-mediated oocyte maturation1.46E-023Q9UJX4, P30260, Q16539ANAPC5, CDC27, MAPK14More
Ampicillinhsa04924Renin secretion4.38E-021P07550ADRB2More
Ampicillinhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Ampicillinhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Ampicillinhsa05133Pertussis4.20E-021P0C0L4C4AMore
Ampicillinhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Ampicillinhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Ampicillinhsa05212Pancreatic cancer3.40E-021P37173TGFBR2More
Ampicillinhsa05216Thyroid cancer2.72E-022P04637, P24522TP53, GADD45AMore
Ampicillinhsa05217Basal cell carcinoma4.79E-022P04637, P24522TP53, GADD45AMore
Ampicillinhsa05218Melanoma2.72E-022P04637, P24522TP53, GADD45AMore
Ampicillinhsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
Ampicillinhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Ampicillinhsa05415Diabetic cardiomyopathy3.59E-021P11413G6PDMore
Pivampicillinhsa03013RNA transport8.19E-047Q15287, Q9UBU9, P35658, P63279, P55884, O15371, P20042RNPS1, NXF1, NUP214, UBE2I, EIF3B, EIF3D, EIF2S2More
Pivampicillinhsa03040Spliceosome3.98E-024Q15427, P38159, P61978, P11142SF3B4, RBMX, HNRPK, HSPA8More
Pivampicillinhsa03060Protein export1.43E-022P37108, Q15005SRP14, SPCS2More
Pivampicillinhsa04012ErbB signaling pathway3.74E-023P21860, Q13557, O14944ERBB3, CAMK2D, EREGMore
Pivampicillinhsa04020Calcium signaling pathway6.50E-046Q96DU7, P45880, Q13557, P21860, P51828, P23634ITPKC, VDAC2, CAMK2D, ERBB3, ADCY7, ATP2B4More
Pivampicillinhsa04022cGMP-PKG signaling pathway4.72E-024Q99941, P23634, P51828, P45880CREBL1, ATP2B4, ADCY7, VDAC2More
Pivampicillinhsa04071Sphingolipid signaling pathway1.94E-026Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2More
Pivampicillinhsa04141Protein processing in endoplasmic reticulum3.64E-025Q99941, O75460, P11142, Q9H3Z4, P07900CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1More
Pivampicillinhsa04261Adrenergic signaling in cardiomyocytes3.98E-024P51828, Q99941, Q13557, P23634ADCY7, CREBL1, CAMK2D, ATP2B4More
Pivampicillinhsa04330Notch signaling pathway4.34E-022Q92542, P46531NCSTN, NOTCH1More
Pivampicillinhsa04340Hedgehog signaling pathway1.80E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Pivampicillinhsa04668TNF signaling pathway4.74E-023Q99941, P01584, O95429CREBL1, IL1B, BAG4More
Pivampicillinhsa04750Inflammatory mediator regulation of TRP channels3.74E-023P01584, P51828, Q13557IL1B, ADCY7, CAMK2DMore
Pivampicillinhsa04911Insulin secretion1.48E-023P51828, Q99941, Q13557ADCY7, CREBL1, CAMK2DMore
Pivampicillinhsa04915Estrogen signaling pathway4.72E-024Q99941, P51828, P07900, P11142CREBL1, ADCY7, HSP90AA1, HSPA8More
Pivampicillinhsa04924Renin secretion3.64E-023P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Pivampicillinhsa04925Aldosterone synthesis and secretion5.19E-034Q99941, P51828, Q13557, P23634CREBL1, ADCY7, CAMK2D, ATP2B4More
Pivampicillinhsa04934Cushing syndrome3.48E-034Q99941, P51828, O15169, Q13557CREBL1, ADCY7, AXIN1, CAMK2DMore
Pivampicillinhsa04971Gastric acid secretion1.48E-023P51828, P15311, Q13557ADCY7, VIL2, CAMK2DMore
Pivampicillinhsa05010Alzheimer disease2.07E-027Q92542, P05496, P12074, O75460, P01584, O15169, P45880NCSTN, ATP5G1, COX6A1, ERN1, IL1B, AXIN1, VDAC2More
Pivampicillinhsa05020Prion disease1.81E-027P01584, P46531, P11142, P05496, P12074, P45880, Q99941IL1B, NOTCH1, HSPA8, ATP5G1, COX6A1, VDAC2, CREBL1More
Pivampicillinhsa05144Malaria4.92E-024O60603, P01375, P35443, P26718TLR2, TNF, THBS4, KLRK1More
Pivampicillinhsa05206MicroRNAs in cancer2.97E-036P15311, P21860, P61978, P46531, P63279, P22105VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXBMore
Pivampicillinhsa05321Inflammatory bowel disease4.92E-024O60603, P01375, Q14765, Q9UL17TLR2, TNF, STAT4, TBX21More
Pivampicillinhsa05332Graft-versus-host disease1.80E-024P10747, P01375, P26715, Q13241CD28, TNF, KLRC1, KLRD1More

Community members of Ampicillin (SDC: 1.64)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q02763TEKAngiopoietinNone1 receptorReported00.32060.62360.43041.8379
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
Q16762TSTThiosulfate sulfurtransferasePredicted00.19330.14580.16810.5563
P11413G6PDGlucoseNone6Nonephosphate 1NonedehydrogenasePredicted10.44350.63690.29291.7884
P04637TP53Cellular tumor antigen p53Predicted10.10040.041711.1336
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
TEKQ02763Kd82000