PharmaCoNets of Aminosalicylic-acid (SPCN: 55.62 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Aminosalicylic-acidhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Aminosalicylic-acidhsa00250Alanine, aspartate and glutamate metabolism4.51E-021P51649ALDH5A1More
Aminosalicylic-acidhsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Aminosalicylic-acidhsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Aminosalicylic-acidhsa00531Glycosaminoglycan degradation3.03E-021P15586GNSMore
Aminosalicylic-acidhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Aminosalicylic-acidhsa00600Sphingolipid metabolism4.50E-021P15289ARSAMore
Aminosalicylic-acidhsa00920Sulfur metabolism3.18E-021Q16762TSTMore
Aminosalicylic-acidhsa00970Aminoacyl-tRNA biosynthesis3.78E-022O95363, Q15046FARS2, KARSMore
Aminosalicylic-acidhsa00980Metabolism of xenobiotics by cytochrome P4505.46E-032Q16772, P09211GSTA3, GSTP1More
Aminosalicylic-acidhsa00982Drug metabolism - cytochrome P4501.06E-022Q16772, P09211GSTA3, GSTP1More
Aminosalicylic-acidhsa00983Drug metabolism - other enzymes1.72E-022Q16772, P09211GSTA3, GSTP1More
Aminosalicylic-acidhsa01100Metabolic pathways8.43E-0311P35790, Q16772, P09211, Q9UJ14, P30041, P40926, Q7KZN9, P15121, Q9UHK6, Q86VZ5, Q9BQB6CHKA, GSTA3, GSTP1, GGTL3, PRDX6, MDH2, COX15, AKR1B1, AMACR, SGMS1, VKORC1More
Aminosalicylic-acidhsa01523Antifolate resistance1.68E-022Q92820, P04818GGH, TYMSMore
Aminosalicylic-acidhsa01524Platinum drug resistance4.58E-034P04637, P48023, Q16772, P09211TP53, FASLG, GSTA3, GSTP1More
Aminosalicylic-acidhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Aminosalicylic-acidhsa03010Ribosome1.88E-026P62753, P25398, P32969, P62829, P18077, P36578RPS6, RPS12, RPL9, RPL23, RPL35A, RPL4More
Aminosalicylic-acidhsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Aminosalicylic-acidhsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Aminosalicylic-acidhsa03040Spliceosome1.28E-0513O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Aminosalicylic-acidhsa04014Ras signaling pathway2.36E-028P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1More
Aminosalicylic-acidhsa04015Rap1 signaling pathway2.69E-0311P20827, P49767, Q96FS4, P11215, P25116, Q8TEU7, Q13009, Q7LDG7, P42338, P08514, P19174EFNA1, VEGFC, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, RASGRP2, PIK3CB, ITGA2B, PLCG1More
Aminosalicylic-acidhsa04062Chemokine signaling pathway9.23E-0310P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, Q8WYR1FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, PIK3R5More
Aminosalicylic-acidhsa04068FoxO signaling pathway6.45E-032P48023, Q96BR1FASLG, SGK3More
Aminosalicylic-acidhsa04071Sphingolipid signaling pathway9.70E-047P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Aminosalicylic-acidhsa04110Cell cycle6.63E-046P06493, O60566, P30304, P33981, P42773, P01106CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYCMore
Aminosalicylic-acidhsa04120Ubiquitin mediated proteolysis1.68E-022O00762, Q14139UBE2C, UBE4AMore
Aminosalicylic-acidhsa04122Sulfur relay system3.18E-021Q16762TSTMore
Aminosalicylic-acidhsa04140Autophagy - animal3.72E-025P22694, Q14643, P10415, Q9H1Y0, Q04759PRKACB, ITPR1, BCL2, ATG5, PRKCQMore
Aminosalicylic-acidhsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Aminosalicylic-acidhsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Aminosalicylic-acidhsa04151PI3K-Akt signaling pathway2.80E-0315P42338, P43657, P48023, P04637, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, Q96BR1, P30281PIK3CB, P2RY5, FASLG, TP53, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, SGK3, CCND3More
Aminosalicylic-acidhsa04217Necroptosis4.42E-046P07900, P15104, P05141, P01584, P0C0S5, Q13557HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, CAMK2DMore
Aminosalicylic-acidhsa04360Axon guidance4.04E-026P16333, P20827, O95631, P42338, P07332, P19174NCK1, EFNA1, NTN1, PIK3CB, FES, PLCG1More
Aminosalicylic-acidhsa04371Apelin signaling pathway1.00E-027P63218, P50151, Q8WYR1, Q14814, Q14344, Q13485, P84022GNG5, GNG10, PIK3R5, MEF2D, GNA13, SMAD4, SMAD3More
Aminosalicylic-acidhsa04512ECM-receptor interaction3.73E-022P07359, P08514GP1BA, ITGA2BMore
Aminosalicylic-acidhsa04514Cell adhesion molecules8.19E-033P16109, P56750, O00501SELP, CLDN17, CLDN5More
Aminosalicylic-acidhsa04530Tight junction1.38E-045Q8TEU7, P16989, P56750, O00501, Q14247RAPGEF6, CSDA, CLDN17, CLDN5, CTTNMore
Aminosalicylic-acidhsa04610Complement and coagulation cascades1.03E-033P25116, P09871, P0C0L4F2R, C1S, C4AMore
Aminosalicylic-acidhsa04611Platelet activation5.18E-055P25116, P08514, Q15746, Q8WYR1, P07359F2R, ITGA2B, MYLK, PIK3R5, GP1BAMore
Aminosalicylic-acidhsa04612Antigen processing and presentation3.74E-038P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Aminosalicylic-acidhsa04613Neutrophil extracellular trap formation2.51E-0418P16109, O60603, P05164, P08246, Q9UM07, Q6FI13, O60814, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P07359, O43315, Q16539SELP, TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, H2BC12, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14More
Aminosalicylic-acidhsa04621NOD-like receptor signaling pathway2.27E-029Q9H1Y0, P43490, O00463, Q05823, P01375, P49913, P59665, P59666, P12838ATG5, PBEF1, TRAF5, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Aminosalicylic-acidhsa04640Hematopoietic cell lineage7.12E-0311P13612, P27930, P15144, P25063, P09693, P01732, P01730, P06127, P09564, P13765, P01375ITGA4, IL1R2, ANPEP, CD24, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNFMore
Aminosalicylic-acidhsa04650Natural killer cell mediated cytotoxicity2.88E-0310P01375, O60880, P20963, P48023, Q13241, P26718, O75015, P26717, Q14953, P26715TNF, SH2D1A, CD247, FASLG, KLRD1, KLRK1, FCGR3B, KLRC2, KIR2DS5, KLRC1More
Aminosalicylic-acidhsa04657IL-17 signaling pathway3.87E-038P07900, O00463, Q16539, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Aminosalicylic-acidhsa04658Th1 and Th2 cell differentiation1.48E-027Q04759, P20963, P09693, Q14765, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, STAT4, GATA3, TBX21, HLA-DOBMore
Aminosalicylic-acidhsa04659Th17 cell differentiation1.70E-027P19174, P14784, P14778, P84022, Q13485, P08238, P07766PLCG1, IL2RB, IL1R1, SMAD3, SMAD4, HSP90AB1, CD3EMore
Aminosalicylic-acidhsa04660T cell receptor signaling pathway3.19E-0310P01375, Q9UDY8, Q04759, P10747, O95267, Q08881, P20963, P09693, P01732, Q13191TNF, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD247, CD3G, CD8A, CBLBMore
Aminosalicylic-acidhsa04662B cell receptor signaling pathway1.74E-025P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Aminosalicylic-acidhsa04664Fc epsilon RI signaling pathway2.47E-024P42338, P07948, P19174, P09917PIK3CB, LYN, PLCG1, ALOX5More
Aminosalicylic-acidhsa04672Intestinal immune network for IgA production1.66E-023P10747, P13765, P13612CD28, HLA-DOB, ITGA4More
Aminosalicylic-acidhsa04722Neurotrophin signaling pathway2.27E-022P48023, P04637FASLG, TP53More
Aminosalicylic-acidhsa04810Regulation of actin cytoskeleton2.58E-023Q15746, P08514, P25116MYLK, ITGA2B, F2RMore
Aminosalicylic-acidhsa04924Renin secretion3.64E-023P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Aminosalicylic-acidhsa04927Cortisol synthesis and secretion1.66E-023Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Aminosalicylic-acidhsa04932Non-alcoholic fatty liver disease9.70E-034P18848, P01584, P13073, O15239ATF4, IL1B, COX4I1, NDUFA1More
Aminosalicylic-acidhsa04933AGE-RAGE signaling pathway in diabetic complications3.21E-025P84022, Q13485, P42338, P49767, P19174SMAD3, SMAD4, PIK3CB, VEGFC, PLCG1More
Aminosalicylic-acidhsa04940Type I diabetes mellitus3.64E-023P10747, P13765, P01375CD28, HLA-DOB, TNFMore
Aminosalicylic-acidhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Aminosalicylic-acidhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Aminosalicylic-acidhsa04970Salivary secretion4.92E-024P07550, P22694, Q14643, P49913ADRB2, PRKACB, ITPR1, CAMPMore
Aminosalicylic-acidhsa04976Bile secretion4.50E-021Q9BY07SLC4A5More
Aminosalicylic-acidhsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Aminosalicylic-acidhsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Aminosalicylic-acidhsa05020Prion disease3.37E-037P13591, P01584, P11142, O15239, P13073, P18848, P05141NCAM1, IL1B, HSPA8, NDUFA1, COX4I1, ATF4, SLC25A5More
Aminosalicylic-acidhsa05022Pathways of neurodegeneration - multiple diseases3.80E-026O15239, P13073, P18848, P05141, P01584, Q13557NDUFA1, COX4I1, ATF4, SLC25A5, IL1B, CAMK2DMore
Aminosalicylic-acidhsa05130Pathogenic Escherichia coli infection7.39E-034Q14247, P56750, O00501, P25116CTTN, CLDN17, CLDN5, F2RMore
Aminosalicylic-acidhsa05133Pertussis1.86E-033P09871, P0C0L4, Q02556C1S, C4A, IRF8More
Aminosalicylic-acidhsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Aminosalicylic-acidhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Aminosalicylic-acidhsa05144Malaria5.57E-047P60033, P69905, P68871, O60603, P01375, P35443, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Aminosalicylic-acidhsa05146Amoebiasis1.48E-027P09341, P27930, P01375, O60603, P05089, P22694, P08311CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSGMore
Aminosalicylic-acidhsa05150Staphylococcus aureus infection1.02E-037P21730, P21462, O75015, P59665, P59666, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Aminosalicylic-acidhsa05160Hepatitis C3.81E-022P04637, P48023TP53, FASLGMore
Aminosalicylic-acidhsa05162Measles4.02E-023P11142, P01584, Q9NP90HSPA8, IL1B, RAB9BMore
Aminosalicylic-acidhsa05164Influenza A3.48E-022Q9GZY0, P48023NXF2; NXF2B, FASLGMore
Aminosalicylic-acidhsa05168Herpes simplex virus 1 infection4.54E-034P04637, Q9GZY0, P48023, P98182TP53, NXF2; NXF2B, FASLG, ZNF200More
Aminosalicylic-acidhsa05171Coronavirus disease - COVID-199.72E-037P01584, P62753, P25398, P36578, P32969, P18077, P62829IL1B, RPS6, RPS12, RPL4, RPL9, RPL35A, RPL23More
Aminosalicylic-acidhsa05200Pathways in cancer9.46E-0317Q13751, P42338, P08238, P19174, P43246, P84022, Q13485, Q13547, P30281, P49767, P43657, P63218, P50151, Q14344, Q7LDG7, O75293, P14784LAMB3, PIK3CB, HSP90AB1, PLCG1, MSH2, SMAD3, SMAD4, HDAC1, CCND3, VEGFC, P2RY5, GNG5, GNG10, GNA13, RASGRP2, GADD45B, IL2RBMore
Aminosalicylic-acidhsa05202Transcriptional misregulation in cancer1.78E-0316Q15532, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, LYL1, GADD45AMore
Aminosalicylic-acidhsa05203Viral carcinogenesis4.62E-023Q12933, P42229, Q15283TRAF2, STAT5A, RASA2More
Aminosalicylic-acidhsa05204Chemical carcinogenesis5.46E-032Q16772, P09211GSTA3, GSTP1More
Aminosalicylic-acidhsa05212Pancreatic cancer3.94E-024P42338, P84022, Q13485, O75293PIK3CB, SMAD3, SMAD4, GADD45BMore
Aminosalicylic-acidhsa05219Bladder cancer4.51E-021P04637TP53More
Aminosalicylic-acidhsa05220Chronic myeloid leukemia2.16E-025Q13547, Q13485, P84022, P42338, O75293HDAC1, SMAD4, SMAD3, PIK3CB, GADD45BMore
Aminosalicylic-acidhsa05310Asthma1.66E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Aminosalicylic-acidhsa05321Inflammatory bowel disease1.14E-036O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Aminosalicylic-acidhsa05323Rheumatoid arthritis1.58E-025P01375, P13765, P10747, P09341, O60603TNF, HLA-DOB, CD28, CXCL1, TLR2More
Aminosalicylic-acidhsa05332Graft-versus-host disease2.03E-035P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Aminosalicylic-acidhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Aminosalicylic-acidhsa05415Diabetic cardiomyopathy2.87E-024P05141, O15239, P13073, Q13557SLC25A5, NDUFA1, COX4I1, CAMK2DMore

Community members of Aminosalicylic-acid (SDC: 4.01)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)