PharmaCoNets of Alosetron (SPCN: 214.12 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Alosetronhsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Alosetronhsa00030Pentose phosphate pathway2.25E-033P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Alosetronhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Alosetronhsa00190Oxidative phosphorylation9.24E-063Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Alosetronhsa00220Arginine biosynthesis9.96E-042P05089, P49448ARG1, GLUD2More
Alosetronhsa00230Purine metabolism1.81E-022P20839, Q02153IMPDH1, GUCY1B3More
Alosetronhsa00260Glycine, serine and threonine metabolism1.99E-021P22557ALAS2More
Alosetronhsa00310Lysine degradation4.57E-022Q96KQ7, Q02809EHMT2, PLOD1More
Alosetronhsa00350Tyrosine metabolism3.40E-021P28332ADH6More
Alosetronhsa00500Starch and sucrose metabolism9.82E-063O43451, P46976, P06737MGAM, GYG1, PYGLMore
Alosetronhsa00510N-Glycan biosynthesis3.15E-022P15907, Q9NR34ST6GAL1, MAN1C1More
Alosetronhsa00562Inositol phosphate metabolism2.00E-024P27987, P19174, P42338, Q02252ITPKB, PLCG1, PIK3CB, ALDH6A1More
Alosetronhsa00565Ether lipid metabolism3.94E-021Q8N661TMEM86BMore
Alosetronhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Alosetronhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Alosetronhsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Alosetronhsa00630Glyoxylate and dicarboxylate metabolism4.91E-072P40925, P15104MDH1, GLULMore
Alosetronhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Alosetronhsa00670One carbon pool by folate3.15E-022O95954, Q99707FTCD, MTRMore
Alosetronhsa00730Thiamine metabolism1.55E-032P05186, P24666ALPL, ACP1More
Alosetronhsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Alosetronhsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Alosetronhsa00830Retinol metabolism3.93E-023P00352, Q9BPW9, O75911ALDH1A1, DHRS9, DHRS3More
Alosetronhsa00860Porphyrin and chlorophyll metabolism3.15E-022P36551, P30043CPOX, BLVRBMore
Alosetronhsa00970Aminoacyl-tRNA biosynthesis2.41E-043O95363, P54136, P14868FARS2, RARS1, DARSMore
Alosetronhsa00980Metabolism of xenobiotics by cytochrome P4508.40E-043P78417, P28332, P11712GSTO1, ADH6, CYP2C9More
Alosetronhsa00982Drug metabolism - cytochrome P4508.40E-043P11712, P78417, P28332CYP2C9, GSTO1, ADH6More
Alosetronhsa00983Drug metabolism - other enzymes3.32E-023P04183, P32320, P05164TK1, CDA, MPOMore
Alosetronhsa01100Metabolic pathways4.43E-0223Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Alosetronhsa01230Biosynthesis of amino acids3.13E-036P51854, P60891, Q99707, P50213, P05089, P37837TKTL1, PRPS1, MTR, IDH3A, ARG1, TALDO1More
Alosetronhsa01523Antifolate resistance1.88E-034P41440, Q92820, P04818, P01375SLC19A1, GGH, TYMS, TNFMore
Alosetronhsa03013RNA transport3.18E-1227P62826, O14980, P52298, Q09161, O14893, P61326, P38919, Q15287, Q9UBU9, Q9H307, P37198, Q7Z3B4, P35658, P63279, P68104, Q14152, P55884, O15371, O75822, P78345, P20042, Q14240, Q9BZI7, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, EIF4A3, RNPS1, NXF1, PNN, NUP62, NUP54, NUP214, UBE2I, EEF1A1, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, EIF2S2, EIF4A2, UPF3B, TACC3, EIF2B1, FMR1, FXR1More
Alosetronhsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Alosetronhsa03020RNA polymerase6.63E-054P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Alosetronhsa03040Spliceosome6.63E-0612Q14562, O43143, O60508, P08579, Q15427, P38159, P61978, Q07955, Q01130, Q13243, P11142, O43447DHX8, DHX15, CDC40, SNRPB2, SF3B4, RBMX, HNRPK, SFRS1, SFRS2, SFRS5, HSPA8, PPIHMore
Alosetronhsa03050Proteasome4.83E-021P55036PSMD4More
Alosetronhsa03060Protein export1.20E-032P37108, Q15005SRP14, SPCS2More
Alosetronhsa03430Mismatch repair4.38E-021P20585MSH3More
Alosetronhsa03450Non-homologous end-joining3.17E-032Q9NP87, P13010POLM, XRCC5More
Alosetronhsa04012ErbB signaling pathway2.62E-037P21860, P16333, P17252, Q13557, P19174, O14944, P42338ERBB3, NCK1, PRKCA, CAMK2D, PLCG1, EREG, PIK3CBMore
Alosetronhsa04014Ras signaling pathway7.71E-0410P42338, P20827, P49767, Q13009, P17252, P14921, P0DP23, P62873, P50151, P19174PIK3CB, EFNA1, VEGFC, TIAM1, PRKCA, ETS1, CALM1, GNB1, GNG10, PLCG1More
Alosetronhsa04015Rap1 signaling pathway1.42E-0310P20827, P49767, P06213, P11215, Q13009, O00522, P42338, P0DP23, P17252, P19174EFNA1, VEGFC, INSR, ITGAM, TIAM1, KRIT1, PIK3CB, CALM1, PRKCA, PLCG1More
Alosetronhsa04020Calcium signaling pathway3.50E-0514P27987, Q96DU7, Q08828, P45880, Q13557, P17252, P21860, O15399, P19174, P0DP23, P05141, P51828, P23634, P49767ITPKB, ITPKC, ADCY1, VDAC2, CAMK2D, PRKCA, ERBB3, GRIN2D, PLCG1, CALM1, SLC25A5, ADCY7, ATP2B4, VEGFCMore
Alosetronhsa04022cGMP-PKG signaling pathway6.39E-049Q99941, P18848, P23634, P31751, Q08828, P51828, P05141, P45880, P0DP23CREBL1, ATF4, ATP2B4, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, CALM1More
Alosetronhsa04024cAMP signaling pathway6.55E-049Q08828, P51828, P42338, P31751, P0DP23, Q13370, O15399, P25963, Q13009ADCY1, ADCY7, PIK3CB, AKT2, CALM1, PDE3B, GRIN2D, NFKBIA, TIAM1More
Alosetronhsa04060Cytokine-cytokine receptor interaction5.34E-0311P14784, P27930, P14778, P26842, Q06643, Q13651, P25024, Q9UBD3, P47992, P09341, P01730IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, CXCR1, XCL2, XCL1, CXCL1, CD4More
Alosetronhsa04061Viral protein interaction with cytokine and cytokine receptor1.13E-049Q8NHW4, P09341, P25024, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Alosetronhsa04062Chemokine signaling pathway2.78E-0416P25024, P09341, P47992, Q9UBD3, P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q08881, Q13009, P14598, P42224, P25963CXCR1, CXCL1, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ITK, TIAM1, NCF1, STAT1, NFKBIAMore
Alosetronhsa04064NF-kappa B signaling pathway3.60E-1323P10415, Q13489, P25963, P51617, O00463, P14778, P01584, P01375, P29965, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, IL1R1, IL1B, TNF, CD40LG, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, LTB, CYLDMore
Alosetronhsa04070Phosphatidylinositol signaling system1.66E-0712P19174, P0DP23, Q14643, P42338, O14986, P23743, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIK3CB, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Alosetronhsa04071Sphingolipid signaling pathway3.45E-058P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Alosetronhsa04072Phospholipase D signaling pathway2.40E-036P31751, O14986, Q15438, Q08828, P51828, Q16760AKT2, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKDMore
Alosetronhsa04080Neuroactive ligand-receptor interaction3.11E-0410P08311, Q15722, P21453, Q9H228, P43657, O00398, P21462, P21730, P14416, P35318CTSG, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, FPR1, C5AR1, DRD2, ADMMore
Alosetronhsa04110Cell cycle6.63E-046P06493, O60566, P30304, P33981, P42773, P01106CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYCMore
Alosetronhsa04114Oocyte meiosis5.20E-049P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5DMore
Alosetronhsa04115p53 signaling pathway3.57E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Alosetronhsa04120Ubiquitin mediated proteolysis4.51E-044Q9UBT2, O95071, Q14669, P0CG47SAE2, UBR5, TRIP12, UBBMore
Alosetronhsa04137Mitophagy - animal9.52E-032Q07817, P0CG47BCL2L1, UBBMore
Alosetronhsa04140Autophagy - animal5.56E-0310P31751, Q7L523, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9AKT2, RRAGA, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Alosetronhsa04141Protein processing in endoplasmic reticulum3.64E-025Q99941, O75460, P11142, Q9H3Z4, P07900CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1More
Alosetronhsa04142Lysosome1.46E-027P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Alosetronhsa04144Endocytosis1.67E-028P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Alosetronhsa04145Phagosome2.67E-0711O75015, Q15080, P14598, Q13509, P68371, Q13488, P05164, P78380, O60603, P35443, P13765FCGR3B, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Alosetronhsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Alosetronhsa04151PI3K-Akt signaling pathway2.09E-0316P42338, P25116, P20827, P49767, Q13362, P08238, P62873, P50151, P16144, O15335, Q13751, O60603, P14784, P01568, P10415, P17252PIK3CB, F2R, EFNA1, VEGFC, PPP2R5C, HSP90AB1, GNB1, GNG10, ITGB4, CHAD, LAMB3, TLR2, IL2RB, IFNA21, BCL2, PRKCAMore
Alosetronhsa04210Apoptosis1.52E-029Q13315, P10415, Q13489, P25963, P01375, P24522, Q16548, Q13077, Q14643ATM, BCL2, BIRC3, NFKBIA, TNF, GADD45A, BCL2A1, TRAF1, ITPR1More
Alosetronhsa04211Longevity regulating pathway1.88E-024P31751, Q08828, P51828, P18848AKT2, ADCY1, ADCY7, ATF4More
Alosetronhsa04213Longevity regulating pathway - multiple species3.11E-034P31751, Q08828, P51828, P0DMV8AKT2, ADCY1, ADCY7, HSPA1AMore
Alosetronhsa04217Necroptosis8.40E-0510P01568, Q13489, Q13546, P42224, P08238, P15104, Q6FI13, P10415, O43633, Q08752IFNA21, BIRC3, RIPK1, STAT1, HSP90AB1, GLUL, H2AC18; H2AC19, BCL2, CHMP2A, PPIDMore
Alosetronhsa04261Adrenergic signaling in cardiomyocytes1.04E-0513P09493, Q08828, P51828, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, Q13557, P17252, P10415, P23634TPM1, ADCY1, ADCY7, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CAMK2D, PRKCA, BCL2, ATP2B4More
Alosetronhsa04270Vascular smooth muscle contraction6.96E-036P0DP23, Q08828, P51828, P35579, P35749, P35318CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Alosetronhsa04330Notch signaling pathway2.46E-033Q92542, P49768, P46531NCSTN, PSEN1, NOTCH1More
Alosetronhsa04340Hedgehog signaling pathway3.46E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Alosetronhsa04360Axon guidance1.16E-047P16333, P20827, O95631, P17252, P42338, P23528, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, CFL1, PLCG1More
Alosetronhsa04370VEGF signaling pathway1.04E-046P19174, P16298, P42338, P17252, Q05397, Q02750PLCG1, PPP3CB, PIK3CB, PRKCA, PTK2, MAP2K1More
Alosetronhsa04371Apelin signaling pathway3.94E-024P31751, Q08828, P51828, P0DP23AKT2, ADCY1, ADCY7, CALM1More
Alosetronhsa04380Osteoclast differentiation5.27E-0410Q9NQC7, Q9UQC2, Q16539, P23458, P31751, P01584, P14778, O75015, P01375, Q8N149CYLD, GAB2, MAPK14, JAK1, AKT2, IL1B, IL1R1, FCGR3B, TNF, LILRA2More
Alosetronhsa04390Hippo signaling pathway5.79E-034P04628, Q9UJU2, O43623, Q13489WNT1, LEF1, SNAI2, BIRC3More
Alosetronhsa04510Focal adhesion7.77E-039P16144, O75369, P42338, Q15942, P17252, O15335, Q13751, Q13489, P49767ITGB4, FLNB, PIK3CB, ZYX, PRKCA, CHAD, LAMB3, BIRC3, VEGFCMore
Alosetronhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Alosetronhsa04540Gap junction1.29E-024P17252, Q13509, P68371, Q14643PRKCA, TUBB3, TUBB2C, ITPR1More
Alosetronhsa04612Antigen processing and presentation2.97E-0810P13765, P48382, P01730, P26715, P26717, Q07444, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, TNFMore
Alosetronhsa04613Neutrophil extracellular trap formation1.64E-0721P17252, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Alosetronhsa04620Toll-like receptor signaling pathway2.54E-033P01584, P31751, Q8NHW4IL1B, AKT2, CCL4L2More
Alosetronhsa04621NOD-like receptor signaling pathway3.25E-0515Q16539, Q14643, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, P29728, Q05823, P01375, P09341, P49913, P12838MAPK14, ITPR1, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Alosetronhsa04623Cytosolic DNA-sensing pathway1.40E-086P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Alosetronhsa04625C-type lectin receptor signaling pathway1.14E-038Q9ULY5, P01584, Q9NQC7, P20749, P01375, P31751, P0DP23, Q16539CLEC4E, IL1B, CYLD, BCL3, TNF, AKT2, CALM1, MAPK14More
Alosetronhsa04630JAK-STAT signaling pathway4.54E-023P31751, P23458, Q13651AKT2, JAK1, IL10RAMore
Alosetronhsa04640Hematopoietic cell lineage1.73E-0613P13612, P14778, P27930, P15144, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375ITGA4, IL1R1, IL1R2, ANPEP, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNFMore
Alosetronhsa04650Natural killer cell mediated cytotoxicity7.44E-1214P16298, P50591, P01375, P06239, O60880, P20963, Q02750, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, TNF, LCK, SH2D1A, CD247, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Alosetronhsa04657IL-17 signaling pathway2.02E-057O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Alosetronhsa04658Th1 and Th2 cell differentiation5.48E-1613Q04759, P07766, P20963, P09693, Q16539, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Alosetronhsa04659Th17 cell differentiation2.62E-1217P25963, Q04759, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, HSP90AB1, CD3E, CD3G, CD247More
Alosetronhsa04660T cell receptor signaling pathway8.59E-1316P01375, P25963, Q9UDY8, Q04759, P10747, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841TNF, NFKBIA, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Alosetronhsa04662B cell receptor signaling pathway1.49E-035P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Alosetronhsa04664Fc epsilon RI signaling pathway1.25E-048P01375, Q16539, P42338, P17252, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, PRKCA, GAB2, LYN, PLCG1, ALOX5More
Alosetronhsa04666Fc gamma R-mediated phagocytosis5.57E-057P42338, P19174, P23528, P06396, O14494, P14598, P17252PIK3CB, PLCG1, CFL1, GSN, PLPP1, NCF1, PRKCAMore
Alosetronhsa04668TNF signaling pathway2.41E-0411P01375, O00463, Q13489, Q16539, P25963, Q99941, P01584, P20749, Q13077, P14780, O95429TNF, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, IL1B, BCL3, TRAF1, MMP9, BAG4More
Alosetronhsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Alosetronhsa04672Intestinal immune network for IgA production1.24E-043P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Alosetronhsa04713Circadian entrainment1.05E-048O15399, P0DP23, P17252, P62873, P50151, Q14643, Q08828, P51828GRIN2D, CALM1, PRKCA, GNB1, GNG10, ITPR1, ADCY1, ADCY7More
Alosetronhsa04720Long-term potentiation2.33E-048P17252, P16298, P0DP23, P51812, P18848, Q08828, Q02750, Q14643PRKCA, PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1, ITPR1More
Alosetronhsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Alosetronhsa04723Retrograde endocannabinoid signaling1.88E-024Q14643, P17252, P62873, Q16718ITPR1, PRKCA, GNB1, NDUFA5More
Alosetronhsa04724Glutamatergic synapse1.44E-046O15399, P17252, P62873, P63218, P50151, P15104GRIN2D, PRKCA, GNB1, GNG5, GNG10, GLULMore
Alosetronhsa04725Cholinergic synapse1.18E-0511Q08828, P51828, Q14643, P17252, P62873, P63218, P50151, P18848, P42338, P31751, P10415ADCY1, ADCY7, ITPR1, PRKCA, GNB1, GNG5, GNG10, ATF4, PIK3CB, AKT2, BCL2More
Alosetronhsa04726Serotonergic synapse2.54E-025P17252, P62873, P50151, P33260, P09917PRKCA, GNB1, GNG10, CYP2C18, ALOX5More
Alosetronhsa04727GABAergic synapse5.11E-045P62873, P63218, P50151, P15104, P17252GNB1, GNG5, GNG10, GLUL, PRKCAMore
Alosetronhsa04728Dopaminergic synapse9.19E-048Q14643, P17252, P62873, P31751, P18848, Q13362, Q14738, P0DP23ITPR1, PRKCA, GNB1, AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1More
Alosetronhsa04744Phototransduction5.31E-062P62873, P0DP23GNB1, CALM1More
Alosetronhsa04750Inflammatory mediator regulation of TRP channels1.22E-045P01584, Q08828, P51828, Q13557, P0DP23IL1B, ADCY1, ADCY7, CAMK2D, CALM1More
Alosetronhsa04911Insulin secretion8.29E-045Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Alosetronhsa04912GnRH signaling pathway1.52E-036P17252, Q08828, P51828, P18848, Q14643, P0DP23PRKCA, ADCY1, ADCY7, ATF4, ITPR1, CALM1More
Alosetronhsa04913Ovarian steroidogenesis2.52E-021P06213INSRMore
Alosetronhsa04914Progesterone-mediated oocyte maturation1.51E-048Q17RY0, P42338, Q13370, Q9UJX4, P30304, P08238, P51812, Q02750CPEB4, PIK3CB, PDE3B, ANAPC5, CDC25A, HSP90AB1, RPS6KA3, MAP2K1More
Alosetronhsa04915Estrogen signaling pathway2.87E-0410Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, Q15788CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, NCOA1More
Alosetronhsa04916Melanogenesis3.48E-036P0DP23, Q9UJU2, Q08828, P51828, P17252, P04628CALM1, LEF1, ADCY1, ADCY7, PRKCA, WNT1More
Alosetronhsa04920Adipocytokine signaling pathway4.49E-024P25963, P33121, Q04759, P01375NFKBIA, ACSL1, PRKCQ, TNFMore
Alosetronhsa04922Glucagon signaling pathway3.47E-024Q12778, Q13370, P0DP23, Q14643FOXO1, PDE3B, CALM1, ITPR1More
Alosetronhsa04923Regulation of lipolysis in adipocytes7.59E-044Q08828, P51828, P06213, P31751ADCY1, ADCY7, INSR, AKT2More
Alosetronhsa04924Renin secretion6.88E-043Q14643, Q13370, P0DP23ITPR1, PDE3B, CALM1More
Alosetronhsa04925Aldosterone synthesis and secretion1.35E-047Q99941, P18848, Q08828, P51828, P0DP23, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM1, CAMK2D, ATP2B4More
Alosetronhsa04926Relaxin signaling pathway2.26E-0512P31751, P25963, P42338, P62873, P63218, P50151, P18848, P49767, Q08828, P51828, P17252, P49407AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, ATF4, VEGFC, ADCY1, ADCY7, PRKCA, ARRB1More
Alosetronhsa04927Cortisol synthesis and secretion1.59E-023P18848, Q08828, P51828ATF4, ADCY1, ADCY7More
Alosetronhsa04929GnRH secretion4.62E-022P42338, P49407PIK3CB, ARRB1More
Alosetronhsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Alosetronhsa04932Non-alcoholic fatty liver disease4.38E-048P31751, O43521, P18848, O75460, P01584, P13073, P12074, O95298AKT2, BCL2L11, ATF4, ERN1, IL1B, COX4I1, COX6A1, NDUFC2More
Alosetronhsa04933AGE-RAGE signaling pathway in diabetic complications1.26E-037P42224, P10415, P42338, Q12778, P49767, P17252, P19174STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1More
Alosetronhsa04934Cushing syndrome4.83E-046Q99941, P18848, Q08828, P51828, O15169, Q13557CREBL1, ATF4, ADCY1, ADCY7, AXIN1, CAMK2DMore
Alosetronhsa04935Growth hormone synthesis, secretion and action1.88E-024Q08828, P51828, P18848, P31751ADCY1, ADCY7, ATF4, AKT2More
Alosetronhsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Alosetronhsa04966Collecting duct acid secretion2.86E-022Q13488, Q9Y666TCIRG1, SLC12A7More
Alosetronhsa04970Salivary secretion2.94E-047Q08828, P51828, P22694, Q14643, P17252, P0DP23, P49913ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, CALM1, CAMPMore
Alosetronhsa04971Gastric acid secretion9.27E-055Q08828, P51828, P15311, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM1, CAMK2DMore
Alosetronhsa04976Bile secretion2.10E-046O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Alosetronhsa05010Alzheimer disease6.68E-0520Q92542, Q16718, O95298, O14521, P05496, P12074, Q14643, Q00535, O75460, P0DP23, P01584, P18848, Q13509, P68371, O15169, P31751, P05141, P45880, Q08752, P28070NCSTN, NDUFA5, NDUFC2, SDHD, ATP5G1, COX6A1, ITPR1, CDK5, ERN1, CALM1, IL1B, ATF4, TUBB3, TUBB2C, AXIN1, AKT2, SLC25A5, VDAC2, PPID, PSMB4More
Alosetronhsa05012Parkinson disease2.25E-026Q16718, O14521, Q14643, P0DP23, Q13509, P68371NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2CMore
Alosetronhsa05016Huntington disease1.76E-0310O95298, P13073, P12074, P24928, P30876, P62487, P05141, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4, PSMD12More
Alosetronhsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Alosetronhsa05020Prion disease8.68E-0516P01584, P46531, P11142, Q16718, O14521, P05496, P12074, Q92736, Q14643, P45880, O60282, Q13509, P68371, Q99941, P14598, Q15080IL1B, NOTCH1, HSPA8, NDUFA5, SDHD, ATP5G1, COX6A1, RYR2, ITPR1, VDAC2, KIF5C, TUBB3, TUBB2C, CREBL1, NCF1, NCF4More
Alosetronhsa05022Pathways of neurodegeneration - multiple diseases3.36E-0418Q14643, Q13509, P68371, P10415, Q16718, O95298, O14521, Q8TEV9, O75460, P18848, Q13561, P05141, P17252, Q00535, P01584, Q08752, P0DP23, P28070ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, NDUFC2, SDHD, SMCR8, ERN1, ATF4, DCTN2, SLC25A5, PRKCA, CDK5, IL1B, PPID, CALM1, PSMB4More
Alosetronhsa05032Morphine addiction1.24E-025P62873, P50151, Q13370, P17252, P43250GNB1, GNG10, PDE3B, PRKCA, GRK6More
Alosetronhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Alosetronhsa05110Vibrio cholerae infection3.15E-023Q13488, P17252, P19174TCIRG1, PRKCA, PLCG1More
Alosetronhsa05120Epithelial cell signaling in Helicobacter pylori infection2.32E-034Q16539, P09341, P25024, P25025MAPK14, CXCL1, CXCR1, CXCR2More
Alosetronhsa05131Shigellosis2.65E-0314P01375, P25963, O00463, P68431, Q04759, Q9UDY8, Q9H1Y0, Q14247, Q14643, Q12778, Q13315, P10415, Q08752, Q96A32TNF, NFKBIA, TRAF5, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCQ, MALT1, ATG5, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID, MYLPFMore
Alosetronhsa05132Salmonella infection1.02E-0616P51617, P25963, P01375, Q9UJU2, O00471, Q13546, Q13489, P10415, O75369, Q96A32, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371IRAK1, NFKBIA, TNF, LEF1, EXOC5, RIPK1, BIRC3, BCL2, FLNB, MYLPF, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2CMore
Alosetronhsa05134Legionellosis2.82E-023P01584, Q9NR31, P0DMV8IL1B, SAR1A, HSPA1AMore
Alosetronhsa05140Leishmaniasis4.20E-1013P13612, O75015, P14598, P42224, P13765, O60603, P25963, P01375, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Alosetronhsa05144Malaria7.27E-045P60033, O60603, P01375, P35443, P26718CD81, TLR2, TNF, THBS4, KLRK1More
Alosetronhsa05145Toxoplasmosis3.59E-0514P51617, P25963, P01375, P10415, Q13489, P42224, P28068, P13765, P09917, Q16787, Q13751, P11142, O60603, P29965IRAK1, NFKBIA, TNF, BCL2, BIRC3, STAT1, HLA-DMB, HLA-DOB, ALOX5, LAMA3, LAMB3, HSPA8, TLR2, CD40LGMore
Alosetronhsa05146Amoebiasis1.25E-109P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSGMore
Alosetronhsa05150Staphylococcus aureus infection1.91E-024Q14532, P59665, P59666, P49913KRT32, DEFA1; DEFA1B, DEFA3, CAMPMore
Alosetronhsa05152Tuberculosis3.38E-0612Q13488, P0DP23, P42224, P48382, O60603, P01375, P10415, P13765, P01568, P49913, Q9UDY8, P51617TCIRG1, CALM1, STAT1, RFX5, TLR2, TNF, BCL2, HLA-DOB, IFNA21, CAMP, MALT1, IRAK1More
Alosetronhsa05161Hepatitis B2.33E-028P17252, P14780, P25963, P01375, P10415, P51617, O60603, Q14765PRKCA, MMP9, NFKBIA, TNF, BCL2, IRAK1, TLR2, STAT4More
Alosetronhsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Alosetronhsa05163Human cytomegalovirus infection3.73E-0824P31751, P42338, P01375, P25963, P62873, P50151, Q14643, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, P17252, Q13651, P25025, Q16539, P18848, P04637, O00463, P30101, P01568AKT2, PIK3CB, TNF, NFKBIA, GNB1, GNG10, ITPR1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, PRKCA, IL10RA, CXCR2, MAPK14, ATF4, TP53, TRAF5, PDIA3, IFNA21More
Alosetronhsa05164Influenza A4.49E-025P31751, P01584, P23458, P05141, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, NXF1More
Alosetronhsa05165Human papillomavirus infection4.48E-0310P16144, Q16787, Q05086, P01568, P42224, Q13488, Q02930, Q13362, Q12778, Q13315ITGB4, LAMA3, UBE3A, IFNA21, STAT1, TCIRG1, CREB5, PPP2R5C, FOXO1, ATMMore
Alosetronhsa05166Human T-cell leukemia virus 1 infection5.15E-0310P23458, P05141, P62826, Q08828, P51828, P18848, Q02930, P31751, P28068, Q13315JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, CREB5, AKT2, HLA-DMB, ATMMore
Alosetronhsa05167Kaposi sarcoma-associated herpesvirus infection4.72E-0515P01568, P42224, P25963, P42338, P40189, P62873, P62879, P50151, P19174, P16298, Q14643, Q02750, P0DP23, P0CG47, Q9UJU2IFNA21, STAT1, NFKBIA, PIK3CB, IL6ST, GNB1, GNB2, GNG10, PLCG1, PPP3CB, ITPR1, MAP2K1, CALM1, UBB, LEF1More
Alosetronhsa05168Herpes simplex virus 1 infection5.04E-0517P25963, P01568, P42224, Q07955, Q01130, Q13243, Q13489, P30101, P42338, Q9Y2A4, Q13398, P51522, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Alosetronhsa05169Epstein-Barr virus infection7.34E-0514P13765, P01106, Q13547, O00463, P42338, P07948, Q13761, P24522, O75293, P01375, P29728, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, TNF, OAS2, CD3E, CD3G, CD247More
Alosetronhsa05170Human immunodeficiency virus 1 infection3.41E-1026P42338, Q02750, P62873, P62879, P50151, P16298, P0DP23, P01375, Q05397, P17252, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P23528, P10415, Q13619, Q93034, Q9Y6Q5, P20333PIK3CB, MAP2K1, GNB1, GNB2, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, CFL1, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Alosetronhsa05171Coronavirus disease - COVID-193.30E-027P25963, P42224, P01568, P40189, P42338, P19174, P17252NFKBIA, STAT1, IFNA21, IL6ST, PIK3CB, PLCG1, PRKCAMore
Alosetronhsa05200Pathways in cancer5.69E-0625Q13751, P42338, P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P10826, P14923, P10415, Q13489, P49767, P14921, Q12778, P25116, P62873, P50151, P78417, O75293, P0DP23, P01568, P14784, P40189LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, RARB, JUP, BCL2, BIRC3, VEGFC, ETS1, FOXO1, F2R, GNB1, GNG10, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Alosetronhsa05202Transcriptional misregulation in cancer4.54E-0819Q12778, Q15532, Q13315, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522FOXO1, SS18, ATM, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45AMore
Alosetronhsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Alosetronhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Alosetronhsa05205Proteoglycans in cancer1.09E-0210Q13009, Q12955, Q14643, O75369, P14780, P17252, O60603, P04628, Q13635, P08962TIAM1, ANK3, ITPR1, FLNB, MMP9, PRKCA, TLR2, WNT1, PTCH1, CD63More
Alosetronhsa05206MicroRNAs in cancer2.97E-036P15311, P21860, P61978, P46531, P63279, P22105VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXBMore
Alosetronhsa05212Pancreatic cancer9.49E-046P42338, P31751, Q15311, P23458, P42224, O75293PIK3CB, AKT2, RALBP1, JAK1, STAT1, GADD45BMore
Alosetronhsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Alosetronhsa05214Glioma1.31E-045P0DP23, P17252, P42338, P19174, O75293CALM1, PRKCA, PIK3CB, PLCG1, GADD45BMore
Alosetronhsa05217Basal cell carcinoma4.31E-022P04628, Q9UJU2WNT1, LEF1More
Alosetronhsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Alosetronhsa05222Small cell lung cancer9.25E-0410P10826, P42338, Q13751, Q13489, P10415, P25963, Q13077, O00463, P24522, O75293RARB, PIK3CB, LAMB3, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A, GADD45BMore
Alosetronhsa05223Non-small cell lung cancer4.91E-035P17252, P42338, P19174, P10826, O75293PRKCA, PIK3CB, PLCG1, RARB, GADD45BMore
Alosetronhsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Alosetronhsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Alosetronhsa05231Choline metabolism in cancer4.50E-048P31751, P42338, Q9Y259, P19174, P23743, Q16760, O14986, P17252AKT2, PIK3CB, CHKB, PLCG1, DGKA, DGKD, PIP5K1B, PRKCAMore
Alosetronhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.65E-069O95267, P07766, P20963, P09693, P06239, O60603, Q04759, Q16539, P01730RASGRP1, CD3E, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14, CD4More
Alosetronhsa05310Asthma3.49E-063P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Alosetronhsa05320Autoimmune thyroid disease2.92E-054P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Alosetronhsa05321Inflammatory bowel disease1.52E-107O60603, P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Alosetronhsa05322Systemic lupus erythematosus1.74E-0715P08246, P08311, P09871, P01375, P10747, P13765, P29965, Q6FI13, Q93077, P62807, Q16778, O60814, P68431, P12814, P05455ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1, SSBMore
Alosetronhsa05323Rheumatoid arthritis1.29E-024P13765, Q13488, P10747, O60603HLA-DOB, TCIRG1, CD28, TLR2More
Alosetronhsa05330Allograft rejection1.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Alosetronhsa05332Graft-versus-host disease1.82E-075P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Alosetronhsa05340Primary immunodeficiency2.19E-024P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Alosetronhsa05415Diabetic cardiomyopathy3.55E-025P17252, P14598, Q15080, Q16718, O14521PRKCA, NCF1, NCF4, NDUFA5, SDHDMore
Alosetronhsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Alosetronhsa05418Fluid shear stress and atherosclerosis3.33E-0612Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Alosetron (SDC: 9.15)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P10415BCL2Apoptosis regulator BclNone2Predicted10.03410.527112.0714
Q07817BCL2L1BclNone2Nonelike protein 1Predicted10.08720.434911.9134
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
Q9UGN5PARP2Poly [ADPNoneribose] polymerase 2Predicted00.04350.26350.24610.7947
O95271TNKSPoly [ADPNoneribose] polymerase tankyraseNone1Predicted00.10170.222400.4957
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
P13866SLC5A1Sodium/glucose cotransporter 1Predicted00.37190.11050.1050.512
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
Q9UBU7DBF4Protein DBF4 homolog APredicted00.00750.19610.2590.655
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
Q16769QPCTGlutaminylNonepeptide cyclotransferasePredicted00.02450.241600.4954
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P49768PSEN1PresenilinNone1Predicted10.26770.65990.33081.7845
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)