PharmaCoNets of Almitrine (SPCN: 3.52 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Almitrinehsa00500Starch and sucrose metabolism1.47E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
Almitrinehsa00730Thiamine metabolism4.07E-022P05186, P24666ALPL, ACP1More
Almitrinehsa01100Metabolic pathways4.43E-0223Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Almitrinehsa04064NF-kappa B signaling pathway2.99E-027O00463, P14778, Q13077, Q16548, Q8WV28, P24522, P09341TRAF5, IL1R1, TRAF1, BCL2A1, BLNK, GADD45A, CXCL1More
Almitrinehsa04657IL-17 signaling pathway4.55E-025O00463, Q16539, P49841, P09341, P14780TRAF5, MAPK14, GSK3B, CXCL1, MMP9More
Almitrinehsa05120Epithelial cell signaling in Helicobacter pylori infection2.45E-024Q16539, P09341, P25024, P25025MAPK14, CXCL1, CXCR1, CXCR2More
Almitrinehsa05140Leishmaniasis2.69E-025O75015, P13765, O60603, P49006, Q16539FCGR3B, HLA-DOB, TLR2, MARCKSL1, MAPK14More
Almitrinehsa05146Amoebiasis4.55E-025P09341, P14778, P27930, O60603, P05089CXCL1, IL1R1, IL1R2, TLR2, ARG1More
Almitrinehsa05163Human cytomegalovirus infection3.64E-027Q14643, P49841, P14778, P25025, Q16539, P04637, O00463ITPR1, GSK3B, IL1R1, CXCR2, MAPK14, TP53, TRAF5More
Almitrinehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Almitrinehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Almitrinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer4.55E-025O95267, P09693, O60603, Q16539, P01730RASGRP1, CD3G, TLR2, MAPK14, CD4More
Almitrinehsa05418Fluid shear stress and atherosclerosis2.62E-026Q16539, P10599, P14780, P04637, P14778, P27930MAPK14, TXN, MMP9, TP53, IL1R1, IL1R2More

Community members of Almitrine (SDC: 2.52)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)