PharmaCoNets of Albendazole (SPCN: 50.74 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Albendazolehsa00010Glycolysis / Gluconeogenesis1.18E-022P60174, P06744TPI1, GPIMore
Albendazolehsa00051Fructose and mannose metabolism3.92E-033P15121, P19367, P08237AKR1B1, HK1, PFKMMore
Albendazolehsa00052Galactose metabolism3.92E-033P08237, P15121, P19367PFKM, AKR1B1, HK1More
Albendazolehsa00053Ascorbate and aldarate metabolism1.80E-022P51648, Q9UEF7ALDH3A2, KLMore
Albendazolehsa00310Lysine degradation4.27E-022Q96KQ7, P51648EHMT2, ALDH3A2More
Albendazolehsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Albendazolehsa00561Glycerolipid metabolism4.36E-033O14494, P51648, P23743PLPP1, ALDH3A2, DGKAMore
Albendazolehsa00564Glycerophospholipid metabolism3.56E-023P48651, Q9Y6K0, P35790PTDSS1, CEPT1, CHKAMore
Albendazolehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Albendazolehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Albendazolehsa00630Glyoxylate and dicarboxylate metabolism2.42E-022P40925, P15104MDH1, GLULMore
Albendazolehsa00970Aminoacyl-tRNA biosynthesis3.78E-022O95363, Q15046FARS2, KARSMore
Albendazolehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Albendazolehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Albendazolehsa01100Metabolic pathways1.28E-0216Q9Y234, P35790, Q16772, P30041, P19367, P48426, P22557, P20839, Q9Y6K0, P15121, P08237, O95861, Q86VZ5, P48651, Q969G6, P14927LIPT1, CHKA, GSTA3, PRDX6, HK1, PIP4K2A, ALAS2, IMPDH1, CEPT1, AKR1B1, PFKM, BPNT1, SGMS1, PTDSS1, RFK, UQCRBMore
Albendazolehsa01200Carbon metabolism1.99E-022P06744, P60174GPI, TPI1More
Albendazolehsa01240Biosynthesis of cofactors4.63E-023Q969G6, P22557, Q9Y234RFK, ALAS2, LIPT1More
Albendazolehsa01521EGFR tyrosine kinase inhibitor resistance2.90E-023P17252, P10415, Q9NRA1PRKCA, BCL2, PDGFCMore
Albendazolehsa01524Platinum drug resistance4.02E-024Q13315, P10415, Q13489, P43246ATM, BCL2, BIRC3, MSH2More
Albendazolehsa03013RNA transport4.49E-025P62826, Q9UBU9, P63279, P68104, Q14232RAN, NXF1, UBE2I, EEF1A1, EIF2B1More
Albendazolehsa03020RNA polymerase6.21E-044P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Albendazolehsa03040Spliceosome1.17E-0815Q14562, O43143, O60508, P08579, P26368, P52298, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, NCBP2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Albendazolehsa04014Ras signaling pathway2.36E-028P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1More
Albendazolehsa04015Rap1 signaling pathway1.79E-028P20827, P49767, Q96FS4, P11215, Q13009, Q7LDG7, P42338, P19174EFNA1, VEGFC, SIPA1, ITGAM, TIAM1, RASGRP2, PIK3CB, PLCG1More
Albendazolehsa04020Calcium signaling pathway2.70E-038Q08828, Q16566, P17252, P25116, P0DP23, P05141, P51828, Q9NRA1ADCY1, CAMK4, PRKCA, F2R, CALM1, SLC25A5, ADCY7, PDGFCMore
Albendazolehsa04022cGMP-PKG signaling pathway4.38E-036P18848, P31751, Q08828, P51828, P05141, P0DP23ATF4, AKT2, ADCY1, ADCY7, SLC25A5, CALM1More
Albendazolehsa04024cAMP signaling pathway3.94E-024Q08828, P51828, P31751, P0DP23ADCY1, ADCY7, AKT2, CALM1More
Albendazolehsa04061Viral protein interaction with cytokine and cytokine receptor4.54E-022Q8NHW4, Q13651CCL4L2, IL10RAMore
Albendazolehsa04062Chemokine signaling pathway9.23E-0310P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, Q8WYR1FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, PIK3R5More
Albendazolehsa04064NF-kappa B signaling pathway6.71E-0512P10415, Q13489, P25963, P51617, Q13546, P01584, Q9UDY8, Q13315, P63279, O75293, Q8NHW4, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, RIPK1, IL1B, MALT1, ATM, UBE2I, GADD45B, CCL4L2, CYLDMore
Albendazolehsa04070Phosphatidylinositol signaling system9.86E-034P0DP23, O14986, Q16760, P48426CALM1, PIP5K1B, DGKD, PIP4K2AMore
Albendazolehsa04071Sphingolipid signaling pathway2.03E-024P17252, P21453, P10415, P01042PRKCA, S1PR1, BCL2, KNG1More
Albendazolehsa04072Phospholipase D signaling pathway7.60E-0511P31751, P25116, P17252, O14986, Q15438, Q08828, P51828, O14494, P23743, Q16760, Q9NRA1AKT2, F2R, PRKCA, PIP5K1B, PSCD1, ADCY1, ADCY7, PLPP1, DGKA, DGKD, PDGFCMore
Albendazolehsa04114Oocyte meiosis1.35E-025P0DP23, Q08828, P51828, Q13362, Q14738CALM1, ADCY1, ADCY7, PPP2R5C, PPP2R5DMore
Albendazolehsa04140Autophagy - animal1.71E-025P31751, Q7L523, O75460, Q96GC9, Q8TEV9AKT2, RRAGA, ERN1, TMEM49, SMCR8More
Albendazolehsa04141Protein processing in endoplasmic reticulum2.77E-025P27824, P30101, P60604, P11142, P08238CANX, PDIA3, UBE2G2, HSPA8, HSP90AB1More
Albendazolehsa04145Phagosome2.46E-036Q15080, P14598, Q13509, P68371, Q13488, P27824NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, CANXMore
Albendazolehsa04151PI3K-Akt signaling pathway3.70E-0212P42338, P43657, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, P30281PIK3CB, P2RY5, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, CCND3More
Albendazolehsa04211Longevity regulating pathway1.88E-024P31751, Q08828, P51828, P18848AKT2, ADCY1, ADCY7, ATF4More
Albendazolehsa04213Longevity regulating pathway - multiple species4.54E-023P31751, Q08828, P51828AKT2, ADCY1, ADCY7More
Albendazolehsa04217Necroptosis3.69E-058P01568, Q13489, Q13546, P42224, P08238, Q6FI13, P10415, O43633IFNA21, BIRC3, RIPK1, STAT1, HSP90AB1, H2AC18; H2AC19, BCL2, CHMP2AMore
Albendazolehsa04261Adrenergic signaling in cardiomyocytes4.98E-047Q08828, P51828, P31751, P18848, Q13362, Q14738, P0DP23ADCY1, ADCY7, AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1More
Albendazolehsa04360Axon guidance4.04E-026P16333, P20827, O95631, P42338, P07332, P19174NCK1, EFNA1, NTN1, PIK3CB, FES, PLCG1More
Albendazolehsa04371Apelin signaling pathway4.77E-0614P62873, P63218, P50151, Q8WYR1, P31751, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, Q16566, P0DP23GNB1, GNG5, GNG10, PIK3R5, AKT2, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, CAMK4, CALM1More
Albendazolehsa04380Osteoclast differentiation1.88E-024Q9NQC7, P23458, P31751, P01584CYLD, JAK1, AKT2, IL1BMore
Albendazolehsa04520Adherens junction8.77E-034Q13485, P84022, O95863, Q15223SMAD4, SMAD3, SNAI1, PVRL1More
Albendazolehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Albendazolehsa04540Gap junction5.44E-034P17252, Q13509, P68371, Q9NRA1PRKCA, TUBB3, TUBB2C, PDGFCMore
Albendazolehsa04610Complement and coagulation cascades3.19E-021P0C0L4C4AMore
Albendazolehsa04613Neutrophil extracellular trap formation1.73E-024Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Albendazolehsa04620Toll-like receptor signaling pathway5.45E-058P51617, Q13546, P01568, P01584, P31751, P42224, P25963, Q8NHW4IRAK1, RIPK1, IFNA21, IL1B, AKT2, STAT1, NFKBIA, CCL4L2More
Albendazolehsa04621NOD-like receptor signaling pathway4.54E-027P08238, P42224, P01568, P25963, Q13489, P10415, Q13546HSP90AB1, STAT1, IFNA21, NFKBIA, BIRC3, BCL2, RIPK1More
Albendazolehsa04623Cytosolic DNA-sensing pathway2.19E-086P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Albendazolehsa04625C-type lectin receptor signaling pathway9.86E-034P01584, Q9NQC7, P31751, P0DP23IL1B, CYLD, AKT2, CALM1More
Albendazolehsa04630JAK-STAT signaling pathway4.54E-023P31751, P23458, Q13651AKT2, JAK1, IL10RAMore
Albendazolehsa04659Th17 cell differentiation1.01E-037P19174, P14784, P14778, P84022, Q13485, P08238, P07766PLCG1, IL2RB, IL1R1, SMAD3, SMAD4, HSP90AB1, CD3EMore
Albendazolehsa04662B cell receptor signaling pathway1.74E-025P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Albendazolehsa04664Fc epsilon RI signaling pathway1.69E-034P42338, P07948, P19174, P09917PIK3CB, LYN, PLCG1, ALOX5More
Albendazolehsa04666Fc gamma R-mediated phagocytosis2.81E-024P23528, O14494, P14598, P17252CFL1, PLPP1, NCF1, PRKCAMore
Albendazolehsa04710Circadian rhythm1.79E-021O15516CLOCKMore
Albendazolehsa04713Circadian entrainment4.54E-023P0DP23, Q08828, P51828CALM1, ADCY1, ADCY7More
Albendazolehsa04720Long-term potentiation2.23E-035P17252, Q16566, P0DP23, P18848, Q08828PRKCA, CAMK4, CALM1, ATF4, ADCY1More
Albendazolehsa04724Glutamatergic synapse4.43E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Albendazolehsa04725Cholinergic synapse2.86E-048Q08828, P51828, P17252, P62873, P18848, Q16566, P31751, P10415ADCY1, ADCY7, PRKCA, GNB1, ATF4, CAMK4, AKT2, BCL2More
Albendazolehsa04727GABAergic synapse4.43E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Albendazolehsa04728Dopaminergic synapse7.83E-035P31751, P18848, Q13362, Q14738, P0DP23AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1More
Albendazolehsa04744Phototransduction8.61E-052P62873, P0DP23GNB1, CALM1More
Albendazolehsa04750Inflammatory mediator regulation of TRP channels9.86E-034P01584, Q08828, P51828, P0DP23IL1B, ADCY1, ADCY7, CALM1More
Albendazolehsa04911Insulin secretion2.40E-023Q08828, P51828, P18848ADCY1, ADCY7, ATF4More
Albendazolehsa04912GnRH signaling pathway1.39E-024Q08828, P51828, P18848, P0DP23ADCY1, ADCY7, ATF4, CALM1More
Albendazolehsa04915Estrogen signaling pathway2.13E-025P18848, Q08828, P51828, P31751, P0DP23ATF4, ADCY1, ADCY7, AKT2, CALM1More
Albendazolehsa04916Melanogenesis1.60E-035P0DP23, Q9UJU2, Q08828, P51828, P17252CALM1, LEF1, ADCY1, ADCY7, PRKCAMore
Albendazolehsa04923Regulation of lipolysis in adipocytes5.15E-033Q08828, P51828, P31751ADCY1, ADCY7, AKT2More
Albendazolehsa04925Aldosterone synthesis and secretion9.43E-046P18848, Q08828, P51828, P0DP23, P17252, Q16566ATF4, ADCY1, ADCY7, CALM1, PRKCA, CAMK4More
Albendazolehsa04926Relaxin signaling pathway2.46E-024P31751, P18848, Q08828, P51828AKT2, ATF4, ADCY1, ADCY7More
Albendazolehsa04927Cortisol synthesis and secretion1.59E-023P18848, Q08828, P51828ATF4, ADCY1, ADCY7More
Albendazolehsa04932Non-alcoholic fatty liver disease1.04E-025P31751, P18848, O75460, P01584, O95298AKT2, ATF4, ERN1, IL1B, NDUFC2More
Albendazolehsa04933AGE-RAGE signaling pathway in diabetic complications3.21E-025P84022, Q13485, P42338, P49767, P19174SMAD3, SMAD4, PIK3CB, VEGFC, PLCG1More
Albendazolehsa04934Cushing syndrome4.54E-023P18848, Q08828, P51828ATF4, ADCY1, ADCY7More
Albendazolehsa04935Growth hormone synthesis, secretion and action1.88E-024Q08828, P51828, P18848, P31751ADCY1, ADCY7, ATF4, AKT2More
Albendazolehsa04961Endocrine and other factor-regulated calcium reabsorption1.22E-023P20020, Q9UEF7, P17252ATP2B1, KL, PRKCAMore
Albendazolehsa04970Salivary secretion1.59E-023Q08828, P51828, P0DP23ADCY1, ADCY7, CALM1More
Albendazolehsa04971Gastric acid secretion2.54E-034Q08828, P51828, P15311, P0DP23ADCY1, ADCY7, VIL2, CALM1More
Albendazolehsa04976Bile secretion1.59E-023Q08828, P51828, Q14032ADCY1, ADCY7, BAATMore
Albendazolehsa05010Alzheimer disease4.94E-039O95298, Q00535, O75460, P0DP23, P01584, P18848, P31751, P05141, P28070NDUFC2, CDK5, ERN1, CALM1, IL1B, ATF4, AKT2, SLC25A5, PSMB4More
Albendazolehsa05016Huntington disease2.24E-027O95298, P24928, P30876, P62487, P05141, O75460, P28070NDUFC2, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4More
Albendazolehsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Albendazolehsa05022Pathways of neurodegeneration - multiple diseases1.67E-029O95298, Q8TEV9, O75460, P18848, P05141, Q00535, P01584, P0DP23, P28070NDUFC2, SMCR8, ERN1, ATF4, SLC25A5, CDK5, IL1B, CALM1, PSMB4More
Albendazolehsa05032Morphine addiction4.43E-023P63218, P50151, P43250GNG5, GNG10, GRK6More
Albendazolehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Albendazolehsa05132Salmonella infection1.58E-0511P51617, P25963, P08238, Q9UJU2, Q13546, Q13489, P10415, O75369, Q13561, Q13509, P68371IRAK1, NFKBIA, HSP90AB1, LEF1, RIPK1, BIRC3, BCL2, FLNB, DCTN2, TUBB3, TUBB2CMore
Albendazolehsa05140Leishmaniasis4.05E-036P14598, P42224, P25963, P29350, P51617, Q15080NCF1, STAT1, NFKBIA, PTPN6, IRAK1, NCF4More
Albendazolehsa05143African trypanosomiasis3.19E-022P69905, P68871HBA2, HBBMore
Albendazolehsa05145Toxoplasmosis1.95E-026P51617, P25963, P10415, Q13489, P42224, P11142IRAK1, NFKBIA, BCL2, BIRC3, STAT1, HSPA8More
Albendazolehsa05152Tuberculosis6.22E-048Q13488, P0DP23, P42224, P25208, P10415, P01568, Q9UDY8, P51617TCIRG1, CALM1, STAT1, NFYB, BCL2, IFNA21, MALT1, IRAK1More
Albendazolehsa05162Measles4.50E-038P51617, P01568, P25963, P42224, P14784, P10747, P11142, P10415IRAK1, IFNA21, NFKBIA, STAT1, IL2RB, CD28, HSPA8, BCL2More
Albendazolehsa05163Human cytomegalovirus infection9.70E-059P31751, P0DP23, Q8NHW4, Q08828, P51828, P23458, P01584, Q13651, P18848AKT2, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, IL1B, IL10RA, ATF4More
Albendazolehsa05164Influenza A4.49E-025P31751, P01584, P23458, P05141, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, NXF1More
Albendazolehsa05166Human T-cell leukemia virus 1 infection2.19E-0315P27824, P23458, P30279, P05141, P21796, P62826, Q08828, P51828, P18848, P84022, Q13485, P07766, P31751, Q92830, P06746CANX, JAK1, CCND2, SLC25A5, VDAC1, RAN, ADCY1, ADCY7, ATF4, SMAD3, SMAD4, CD3E, AKT2, KAT2A, POLBMore
Albendazolehsa05168Herpes simplex virus 1 infection5.65E-0414P25963, P01568, P42224, Q07955, Q01130, Q13243, Q13489, P51617, Q13398, Q9NR11, P17097, P17038, Q03923, P10415NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, IRAK1, ZNF211, ZNF302, ZNF7, ZNF43, ZNF85, BCL2More
Albendazolehsa05170Human immunodeficiency virus 1 infection3.95E-0511P62873, P0DP23, P17252, Q13546, P01568, P51617, P25963, Q13315, P23528, P10415, Q9Y6Q5GNB1, CALM1, PRKCA, RIPK1, IFNA21, IRAK1, NFKBIA, ATM, CFL1, BCL2, AP1M2More
Albendazolehsa05200Pathways in cancer9.99E-0733P04628, Q13751, P42338, P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, Q13547, P14923, P30279, P30281, P10415, Q13489, P49767, Q12778, P43657, P25116, P62873, P63218, P50151, Q14344, Q7LDG7, O75293, P0DP23, P01568, P14784, P01042WNT1, LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, HDAC1, JUP, CCND2, CCND3, BCL2, BIRC3, VEGFC, FOXO1, P2RY5, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP2, GADD45B, CALM1, IFNA21, IL2RB, KNG1More
Albendazolehsa05203Viral carcinogenesis2.62E-039P06746, Q92830, P07948, P30279, P29083, Q15283, P62807, Q93079, O60814POLB, KAT2A, LYN, CCND2, GTF2E1, RASA2, HIST1H2BC, H2BC9, H2BC12More
Albendazolehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Albendazolehsa05212Pancreatic cancer2.74E-037P42338, P31751, Q15311, P23458, P84022, Q13485, O75293PIK3CB, AKT2, RALBP1, JAK1, SMAD3, SMAD4, GADD45BMore
Albendazolehsa05214Glioma2.90E-023P0DP23, Q16566, P17252CALM1, CAMK4, PRKCAMore
Albendazolehsa05215Prostate cancer6.15E-035P10415, Q9UJU2, Q12778, Q9NRA1, P08238BCL2, LEF1, FOXO1, PDGFC, HSP90AB1More
Albendazolehsa05220Chronic myeloid leukemia2.16E-025Q13547, Q13485, P84022, P42338, O75293HDAC1, SMAD4, SMAD3, PIK3CB, GADD45BMore
Albendazolehsa05231Choline metabolism in cancer4.70E-047P31751, Q9NRA1, P23743, Q16760, O14986, O14494, P17252AKT2, PDGFC, DGKA, DGKD, PIP5K1B, PLPP1, PRKCAMore
Albendazolehsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More

Community members of Albendazole (SDC: 3.45)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q71U36TUBA1ATubulin alphaNone1A chainReported00.58880.07010.70941.1439
P68371TUBB2CTubulin betaNone4B chainReported00.28660.0970.64840.9857
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P19784CSNK2A2Casein kinase II subunit alpha'Predicted10.09660.32250.52971.2231
Q13885TUBB2ATubulin betaNone2A chainPredicted00.03980.09630.64840.8609
Q13509TUBB3Tubulin betaNone3 chainPredicted00.09040.09610.64840.8858
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)