PharmaCoNets of Adenosine-phosphate (SPCN: 146.87 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Adenosine-phosphatehsa00010Glycolysis / Gluconeogenesis4.41E-024P04075, P06733, P04406, P60174ALDOA, ENO1, GAPDH, TPI1More
Adenosine-phosphatehsa00030Pentose phosphate pathway1.09E-065P60891, P51854, P08237, P52209, P37837PRPS1, TKTL1, PFKM, PGD, TALDO1More
Adenosine-phosphatehsa00051Fructose and mannose metabolism2.21E-023O14772, P60174, P04075FPGT, TPI1, ALDOAMore
Adenosine-phosphatehsa00052Galactose metabolism6.10E-033P06280, O43451, P35557GLA, MGAM, GCKMore
Adenosine-phosphatehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Adenosine-phosphatehsa00061Fatty acid biosynthesis1.52E-031Q9UKU0ACSL6More
Adenosine-phosphatehsa00071Fatty acid degradation4.55E-031Q9UKU0ACSL6More
Adenosine-phosphatehsa00100Steroid biosynthesis1.84E-031P35610SOAT1More
Adenosine-phosphatehsa00190Oxidative phosphorylation4.56E-037O95298, Q16718, O15239, P12074, P36542, P05496, O14521NDUFC2, NDUFA5, NDUFA1, COX6A1, ATP5C1, ATP5G1, SDHDMore
Adenosine-phosphatehsa00220Arginine biosynthesis1.84E-053P15104, P05089, P49448GLUL, ARG1, GLUD2More
Adenosine-phosphatehsa00230Purine metabolism2.11E-023Q7LG56, P31350, P21589RRM2B, RRM2, NT5EMore
Adenosine-phosphatehsa00240Pyrimidine metabolism6.02E-096Q7LG56, P31350, P21589, P32320, P04183, P04818RRM2B, RRM2, NT5E, CDA, TK1, TYMSMore
Adenosine-phosphatehsa00250Alanine, aspartate and glutamate metabolism4.40E-032P49448, P15104GLUD2, GLULMore
Adenosine-phosphatehsa00280Valine, leucine and isoleucine degradation3.30E-024P55809, Q9HCC0, Q02252, P11310OXCT1, MCCC2, ALDH6A1, ACADMMore
Adenosine-phosphatehsa00310Lysine degradation3.73E-033Q96KQ7, Q02809, P51648EHMT2, PLOD1, ALDH3A2More
Adenosine-phosphatehsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Adenosine-phosphatehsa00440Phosphonate and phosphinate metabolism3.98E-021Q9Y6K0CEPT1More
Adenosine-phosphatehsa00471D-Glutamine and D-glutamate metabolism1.54E-032Q7Z3D6, P49448C14orf159, GLUD2More
Adenosine-phosphatehsa00480Glutathione metabolism3.85E-022Q7LG56, P31350RRM2B, RRM2More
Adenosine-phosphatehsa00500Starch and sucrose metabolism2.31E-074O43451, P46976, P35557, P06737MGAM, GYG1, GCK, PYGLMore
Adenosine-phosphatehsa00512Mucin type O-glycan biosynthesis1.22E-022O95395, Q8N4A0GCNT3, GALNT4More
Adenosine-phosphatehsa00524Neomycin, kanamycin and gentamicin biosynthesis8.73E-041P35557GCKMore
Adenosine-phosphatehsa00562Inositol phosphate metabolism4.55E-022P27987, P42338ITPKB, PIK3CBMore
Adenosine-phosphatehsa00564Glycerophospholipid metabolism2.07E-033P48651, Q9Y6K0, P35790PTDSS1, CEPT1, CHKAMore
Adenosine-phosphatehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Adenosine-phosphatehsa00600Sphingolipid metabolism3.76E-021P15289ARSAMore
Adenosine-phosphatehsa00630Glyoxylate and dicarboxylate metabolism1.57E-053P40925, P40926, P15104MDH1, MDH2, GLULMore
Adenosine-phosphatehsa00730Thiamine metabolism1.55E-032P05186, P24666ALPL, ACP1More
Adenosine-phosphatehsa00740Riboflavin metabolism3.98E-021Q969G6RFKMore
Adenosine-phosphatehsa00770Pantothenate and CoA biosynthesis7.20E-043O95498, Q6ZQY3, Q9NRN7VNN2, GADL1, AASDHPPTMore
Adenosine-phosphatehsa00910Nitrogen metabolism4.40E-032P15104, P49448GLUL, GLUD2More
Adenosine-phosphatehsa00983Drug metabolism - other enzymes2.03E-086P04183, P20839, P32320, Q7LG56, P31350, P05164TK1, IMPDH1, CDA, RRM2B, RRM2, MPOMore
Adenosine-phosphatehsa01040Biosynthesis of unsaturated fatty acids4.28E-021P22307SCP2More
Adenosine-phosphatehsa01100Metabolic pathways1.28E-0455Q9NR34, Q9Y234, P35790, P05089, P21953, Q16772, P15144, P30041, P15104, P42338, O14732, P27987, P32320, Q02153, Q16774, P20839, P00918, P22748, P10768, P55809, P06280, Q16875, O43286, O43451, P53004, Q9Y6K0, P05186, P24666, P08237, P21399, Q9HCC0, P33121, Q9UHK6, P51854, Q86VZ5, P09917, Q9BVK2, P15907, P57054, Q9UNP4, O96024, Q9BX95, P37837, P32321, P49448, P50213, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q969G6, Q13029, Q9NVH6MAN1C1, LIPT1, CHKA, ARG1, BCKDHB, GSTA3, ANPEP, PRDX6, GLUL, PIK3CB, IMPA2, ITPKB, CDA, GUCY1B3, GUK1, IMPDH1, CA2, CA4, ESD, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, BLVRA, CEPT1, ALPL, ACP1, PFKM, ACO1, MCCC2, ACSL1, AMACR, TKTL1, SGMS1, ALOX5, ALG8, ST6GAL1, PIGP, ST3GAL5, B3GALT4, SGPP1, TALDO1, DCTD, GLUD2, IDH3A, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, RFK, PRDM2, TMLHEMore
Adenosine-phosphatehsa01200Carbon metabolism3.30E-0413P04075, P51854, P04406, P08237, P60174, P37837, P06733, O14521, Q9P2R7, P50213, P21399, P10768, Q02252ALDOA, TKTL1, GAPDH, PFKM, TPI1, TALDO1, ENO1, SDHD, SUCLA2, IDH3A, ACO1, ESD, ALDH6A1More
Adenosine-phosphatehsa012102-Oxocarboxylic acid metabolism6.11E-042P21399, P50213ACO1, IDH3AMore
Adenosine-phosphatehsa01212Fatty acid metabolism7.59E-031Q9UKU0ACSL6More
Adenosine-phosphatehsa01230Biosynthesis of amino acids2.08E-0410P60174, P04406, P06733, P04075, P08237, P51854, Q99707, P21399, P50213, P37837TPI1, GAPDH, ENO1, ALDOA, PFKM, TKTL1, MTR, ACO1, IDH3A, TALDO1More
Adenosine-phosphatehsa01522Endocrine resistance3.10E-035P22694, Q9UM47, P04637, P42773, P46527PRKACB, NOTCH3, TP53, CDKN2C, CDKN1BMore
Adenosine-phosphatehsa01523Antifolate resistance1.68E-022Q92820, P04818GGH, TYMSMore
Adenosine-phosphatehsa01524Platinum drug resistance4.94E-022P78417, P52701GSTO1, MSH6More
Adenosine-phosphatehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Adenosine-phosphatehsa03008Ribosome biogenesis in eukaryotes8.16E-033Q9NYH9, P78345, Q9GZY0UTP6, RPP38, NXF2; NXF2BMore
Adenosine-phosphatehsa03010Ribosome8.03E-048P62753, P62829, P46777, P62888, P61927, P61513, P36578, P50914RPS6, RPL23, RPL5, RPL30, RPL37, RPL37A, RPL4, RPL14More
Adenosine-phosphatehsa03013RNA transport4.45E-0516O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, P47813, Q14152, O75822, P78345, Q14240, Q9BZI7, Q9Y6A5, Q06787, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF1AX, EIF3A, EIF3J, RPP38, EIF4A2, UPF3B, TACC3, FMR1, FXR1More
Adenosine-phosphatehsa03015mRNA surveillance pathway3.37E-023O43148, Q9GZY0, P52298RNMT, NXF2; NXF2B, NCBP2More
Adenosine-phosphatehsa03020RNA polymerase2.70E-054P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Adenosine-phosphatehsa03022Basal transcription factors3.50E-023P20226, O00268, Q15544TBP, TAF4, TAF11More
Adenosine-phosphatehsa03040Spliceosome4.80E-0817Q14562, O43143, O60508, P17844, P08579, P26368, P51991, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, DDX5, SNRPB2, U2AF2, HNRPA3, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Adenosine-phosphatehsa03050Proteasome4.83E-021P55036PSMD4More
Adenosine-phosphatehsa03060Protein export2.83E-022P37108, Q15005SRP14, SPCS2More
Adenosine-phosphatehsa03320PPAR signaling pathway9.10E-031Q9UKU0ACSL6More
Adenosine-phosphatehsa03430Mismatch repair4.38E-021P20585MSH3More
Adenosine-phosphatehsa04015Rap1 signaling pathway9.14E-032P06213, O00522INSR, KRIT1More
Adenosine-phosphatehsa04020Calcium signaling pathway2.80E-0512P27987, Q96DU7, Q08828, P21796, P45880, Q13557, P21860, P30679, P19174, P0DP23, P05141, P23634ITPKB, ITPKC, ADCY1, VDAC1, VDAC2, CAMK2D, ERBB3, GNA15, PLCG1, CALM1, SLC25A5, ATP2B4More
Adenosine-phosphatehsa04022cGMP-PKG signaling pathway2.26E-038Q14814, Q99941, P18848, P05141, P21796, P45880, P0DP23, P01042MEF2D, CREBL1, ATF4, SLC25A5, VDAC1, VDAC2, CALM1, KNG1More
Adenosine-phosphatehsa04061Viral protein interaction with cytokine and cytokine receptor4.90E-021Q99731CCL19More
Adenosine-phosphatehsa04062Chemokine signaling pathway2.94E-024P07948, P42338, P50151, P49407LYN, PIK3CB, GNG10, ARRB1More
Adenosine-phosphatehsa04064NF-kappa B signaling pathway3.70E-0817P10415, P51617, O00463, P14778, P01584, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, Q9NQC7BCL2, IRAK1, TRAF5, IL1R1, IL1B, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CYLDMore
Adenosine-phosphatehsa04070Phosphatidylinositol signaling system1.16E-037P19174, P0DP23, O14986, P23743, Q86XP1, P27987, Q96DU7PLCG1, CALM1, PIP5K1B, DGKA, DGKH, ITPKB, ITPKCMore
Adenosine-phosphatehsa04071Sphingolipid signaling pathway1.13E-059P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Adenosine-phosphatehsa04080Neuroactive ligand-receptor interaction1.07E-039P08311, P00734, Q15722, P21453, Q9H228, Q96G91, P21462, P21730, P07550CTSG, F2, LTB4R, S1PR1, EDG8, P2RY11, FPR1, C5AR1, ADRB2More
Adenosine-phosphatehsa04110Cell cycle2.76E-059P30260, P06493, O60566, P04637, P49918, P30304, P33981, P42773, P01106CDC27, CDK1, BUB1B, TP53, CDKN1C, CDC25A, TTK, CDKN2C, MYCMore
Adenosine-phosphatehsa04115p53 signaling pathway1.37E-058P24522, Q13315, Q7LG56, P31350, Q9HA38, P04637, O95067, P10415GADD45A, ATM, RRM2B, RRM2, ZMAT3, TP53, CCNB2, BCL2More
Adenosine-phosphatehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Adenosine-phosphatehsa04141Protein processing in endoplasmic reticulum7.24E-059P18848, P30101, Q15437, Q15436, Q99941, P11142, P07900, P08238, Q9NR31ATF4, PDIA3, SEC23B, SEC23A, CREBL1, HSPA8, HSP90AA1, HSP90AB1, SAR1AMore
Adenosine-phosphatehsa04142Lysosome5.39E-059P22304, P38571, Q13510, Q9UJJ9, P07602, P49279, P61916, Q04900, Q9Y227IDS, LIPA, ASAH1, GNPTG, PSAP, SLC11A1, NPC2, CD164, ENTPD4More
Adenosine-phosphatehsa04144Endocytosis1.09E-0312Q13191, P0DMV8, P11142, Q9H444, P62491, P25024, P43250, Q8WU79, Q14161, P14784, Q9UMY4, Q9Y5X3CBLB, HSPA1A, HSPA8, CHMP4B, RAB11A, CXCR1, GRK6, SMAP1L, GIT2, IL2RB, SNX12, SNX5More
Adenosine-phosphatehsa04145Phagosome1.73E-047O75015, Q15080, P68371, P05164, P78380, P35443, P13765FCGR3B, NCF4, TUBB2C, MPO, OLR1, THBS4, HLA-DOBMore
Adenosine-phosphatehsa04146Peroxisome9.47E-047O43933, O96011, P56589, Q9UKG9, O75521, P33121, Q9UKU0PEX1, PEX11B, PEX3, CROT, ECI2, ACSL1, ACSL6More
Adenosine-phosphatehsa04151PI3K-Akt signaling pathway4.39E-0516P62753, P04637, P27348, P07900, P08238, P62873, P63218, Q16363, P22105, P14784, Q99941, P18848, Q96BR1, O00141, P30279, P56279RPS6, TP53, YWHAQ, HSP90AA1, HSP90AB1, GNB1, GNG5, LAMA4, TNXB, IL2RB, CREBL1, ATF4, SGK3, SGK, CCND2, TCL1AMore
Adenosine-phosphatehsa04211Longevity regulating pathway2.72E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Adenosine-phosphatehsa04213Longevity regulating pathway - multiple species4.79E-022Q08828, P0DMV8ADCY1, HSPA1AMore
Adenosine-phosphatehsa04216Ferroptosis1.52E-021Q9UKU0ACSL6More
Adenosine-phosphatehsa04217Necroptosis1.18E-0617P01375, P23458, P48023, Q9NQC7, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, Q99878, Q13557, Q9H444, O75351, P21796, P45880TNF, JAK1, FASLG, CYLD, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AC14, CAMK2D, CHMP4B, VPS4B, VDAC1, VDAC2More
Adenosine-phosphatehsa04261Adrenergic signaling in cardiomyocytes7.00E-047P07550, P51828, P22694, Q99941, P18848, Q13362, Q13557ADRB2, ADCY7, PRKACB, CREBL1, ATF4, PPP2R5C, CAMK2DMore
Adenosine-phosphatehsa04270Vascular smooth muscle contraction1.47E-034P0DP23, Q08828, P35579, P35318CALM1, ADCY1, MYH9, ADMMore
Adenosine-phosphatehsa04310Wnt signaling pathway2.28E-045P30279, Q13485, O43318, P17612, P67870CCND2, SMAD4, MAP3K7, PRKACA, CSNK2BMore
Adenosine-phosphatehsa04330Notch signaling pathway3.28E-034Q92542, P49768, Q92830, P78504NCSTN, PSEN1, KAT2A, JAG1More
Adenosine-phosphatehsa04340Hedgehog signaling pathway3.91E-021P17612PRKACAMore
Adenosine-phosphatehsa04360Axon guidance2.19E-023P42338, O14639, P24844PIK3CB, ABLIM1, MYL9More
Adenosine-phosphatehsa04380Osteoclast differentiation1.02E-026Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2More
Adenosine-phosphatehsa04510Focal adhesion4.60E-023Q15942, P51636, P30281ZYX, CAV2, CCND3More
Adenosine-phosphatehsa04520Adherens junction3.91E-022Q13485, O43318SMAD4, MAP3K7More
Adenosine-phosphatehsa04550Signaling pathways regulating pluripotency of stem cells2.16E-022P04628, P40189WNT1, IL6STMore
Adenosine-phosphatehsa04610Complement and coagulation cascades4.31E-074P00734, P0C0L4, P05107, P21730F2, C4A, ITGB2, C5AR1More
Adenosine-phosphatehsa04611Platelet activation2.12E-022Q9Y490, P17612TLN1, PRKACAMore
Adenosine-phosphatehsa04612Antigen processing and presentation7.59E-047P13765, P48382, P26715, P26717, Q13241, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Adenosine-phosphatehsa04613Neutrophil extracellular trap formation3.66E-0516P17252, O60603, P05164, P08246, Q9UM07, Q6FI13, P68431, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Adenosine-phosphatehsa04620Toll-like receptor signaling pathway2.22E-043P01584, P45985, Q8NHW4IL1B, MAP2K4, CCL4L2More
Adenosine-phosphatehsa04621NOD-like receptor signaling pathway1.90E-038P01584, P07900, P25963, P43490, Q05823, P01375, P49913, P12838IL1B, HSP90AA1, NFKBIA, PBEF1, RNASEL, TNF, CAMP, DEFA4More
Adenosine-phosphatehsa04622RIG-I-like receptor signaling pathway1.36E-022Q12933, P10145TRAF2, IL8More
Adenosine-phosphatehsa04623Cytosolic DNA-sensing pathway6.29E-063P01584, Q9Y535, Q8NHW4IL1B, POLR3H, CCL4L2More
Adenosine-phosphatehsa04625C-type lectin receptor signaling pathway3.87E-024Q9ULY5, P20749, P01375, Q16539CLEC4E, BCL3, TNF, MAPK14More
Adenosine-phosphatehsa04630JAK-STAT signaling pathway3.09E-033O75925, P40189, Q06124PIAS1, IL6ST, PTPN11More
Adenosine-phosphatehsa04640Hematopoietic cell lineage4.95E-023P01730, P06127, P09564CD4, CD5, CD7More
Adenosine-phosphatehsa04650Natural killer cell mediated cytotoxicity4.34E-038P01375, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Adenosine-phosphatehsa04657IL-17 signaling pathway3.41E-0610P07900, O00463, Q16539, P49841, P09341, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, CXCL1, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Adenosine-phosphatehsa04658Th1 and Th2 cell differentiation1.75E-0512Q04759, P07766, P20963, Q16539, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, Q13761PRKCQ, CD3E, CD247, MAPK14, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Adenosine-phosphatehsa04659Th17 cell differentiation1.01E-0616Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P14778, Q9HBE5, Q9UL17, Q13485, P07900, P08238, P07766, P09693, P20963PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, IL1R1, IL21R, TBX21, SMAD4, HSP90AA1, HSP90AB1, CD3E, CD3G, CD247More
Adenosine-phosphatehsa04660T cell receptor signaling pathway2.11E-0614P01375, Q04759, P10747, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841TNF, PRKCQ, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Adenosine-phosphatehsa04662B cell receptor signaling pathway1.12E-055P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Adenosine-phosphatehsa04664Fc epsilon RI signaling pathway3.92E-056P01375, Q16539, P42338, Q9UQC2, P07948, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, ALOX5More
Adenosine-phosphatehsa04666Fc gamma R-mediated phagocytosis2.66E-025O75015, P06396, O14494, Q9UQC2, P17252FCGR3B, GSN, PLPP1, GAB2, PRKCAMore
Adenosine-phosphatehsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
Adenosine-phosphatehsa04710Circadian rhythm4.40E-021O15516CLOCKMore
Adenosine-phosphatehsa04713Circadian entrainment4.76E-024P0DP23, Q13557, P62873, P63218CALM1, CAMK2D, GNB1, GNG5More
Adenosine-phosphatehsa04714Thermogenesis8.35E-035P51828, P62753, Q9UKU0, P12074, O15239ADCY7, RPS6, ACSL6, COX6A1, NDUFA1More
Adenosine-phosphatehsa04721Synaptic vesicle cycle3.77E-021P43003SLC1A3More
Adenosine-phosphatehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Adenosine-phosphatehsa04724Glutamatergic synapse3.88E-044O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Adenosine-phosphatehsa04725Cholinergic synapse4.15E-047P51828, P62873, P63218, P50151, P18848, Q13557, P42338ADCY7, GNB1, GNG5, GNG10, ATF4, CAMK2D, PIK3CBMore
Adenosine-phosphatehsa04727GABAergic synapse3.26E-055P62873, P63218, P50151, P15104, P46459GNB1, GNG5, GNG10, GLUL, NSFMore
Adenosine-phosphatehsa04728Dopaminergic synapse3.11E-0411P62873, P63218, P50151, P49841, Q99941, P18848, Q16539, Q13557, P49407, P0DP23, P48058GNB1, GNG5, GNG10, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, CALM1, GRIA4More
Adenosine-phosphatehsa04740Olfactory transduction9.79E-033P62873, Q13557, P0DP23GNB1, CAMK2D, CALM1More
Adenosine-phosphatehsa04742Taste transduction3.91E-021P17612PRKACAMore
Adenosine-phosphatehsa04744Phototransduction1.42E-022P62873, P0DP23GNB1, CALM1More
Adenosine-phosphatehsa04750Inflammatory mediator regulation of TRP channels6.12E-047P01584, Q08828, Q13557, P19174, P24723, P0DP23, P01042IL1B, ADCY1, CAMK2D, PLCG1, PRKCH, CALM1, KNG1More
Adenosine-phosphatehsa04911Insulin secretion5.39E-055P51828, P22694, Q99941, P18848, Q13557ADCY7, PRKACB, CREBL1, ATF4, CAMK2DMore
Adenosine-phosphatehsa04912GnRH signaling pathway5.60E-049P17252, Q08828, P51828, P18848, Q13557, Q16539, Q9Y6R4, Q14643, P0DP23PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, MAPK14, MAP3K4, ITPR1, CALM1More
Adenosine-phosphatehsa04913Ovarian steroidogenesis2.52E-021P06213INSRMore
Adenosine-phosphatehsa04915Estrogen signaling pathway1.13E-0710Q99941, P18848, Q08828, P51828, P07900, P08238, P0DMV8, P11142, P0DP23, Q15788CREBL1, ATF4, ADCY1, ADCY7, HSP90AA1, HSP90AB1, HSPA1A, HSPA8, CALM1, NCOA1More
Adenosine-phosphatehsa04916Melanogenesis3.82E-023Q13557, P0DP23, Q08828CAMK2D, CALM1, ADCY1More
Adenosine-phosphatehsa04918Thyroid hormone synthesis1.94E-045P22694, P51828, Q99941, P18848, P02768PRKACB, ADCY7, CREBL1, ATF4, ALBMore
Adenosine-phosphatehsa04920Adipocytokine signaling pathway1.88E-043Q06124, Q9UKU0, Q9Y478PTPN11, ACSL6, PRKAB1More
Adenosine-phosphatehsa04921Oxytocin signaling pathway4.38E-024P0DP23, Q08828, Q13557, Q96RR4CALM1, ADCY1, CAMK2D, CAMKK2More
Adenosine-phosphatehsa04923Regulation of lipolysis in adipocytes5.74E-033P22694, P07550, P06213PRKACB, ADRB2, INSRMore
Adenosine-phosphatehsa04924Renin secretion1.45E-044P22694, P07550, Q14643, P0DP23PRKACB, ADRB2, ITPR1, CALM1More
Adenosine-phosphatehsa04925Aldosterone synthesis and secretion3.47E-045Q99941, P18848, P51828, P0DP23, Q13557CREBL1, ATF4, ADCY7, CALM1, CAMK2DMore
Adenosine-phosphatehsa04926Relaxin signaling pathway5.84E-069P42338, P63218, P50151, Q99941, P18848, P49767, P51828, P30679, P49407PIK3CB, GNG5, GNG10, CREBL1, ATF4, VEGFC, ADCY7, GNA15, ARRB1More
Adenosine-phosphatehsa04927Cortisol synthesis and secretion1.73E-044Q99941, P18848, P51828, P22694CREBL1, ATF4, ADCY7, PRKACBMore
Adenosine-phosphatehsa04928Parathyroid hormone synthesis, secretion and action2.17E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Adenosine-phosphatehsa04929GnRH secretion1.54E-032P42338, P49407PIK3CB, ARRB1More
Adenosine-phosphatehsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Adenosine-phosphatehsa04931Insulin resistance1.48E-022Q06124, Q9Y478PTPN11, PRKAB1More
Adenosine-phosphatehsa04932Non-alcoholic fatty liver disease2.27E-059P01375, P49841, O43521, P48023, O75460, P01584, P12074, O15239, O95298TNF, GSK3B, BCL2L11, FASLG, ERN1, IL1B, COX6A1, NDUFA1, NDUFC2More
Adenosine-phosphatehsa04934Cushing syndrome1.15E-046Q99941, P18848, P51828, P22694, Q13557, P46527CREBL1, ATF4, ADCY7, PRKACB, CAMK2D, CDKN1BMore
Adenosine-phosphatehsa04935Growth hormone synthesis, secretion and action2.72E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Adenosine-phosphatehsa04940Type I diabetes mellitus5.08E-054P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Adenosine-phosphatehsa04950Maturity onset diabetes of the young8.73E-041P35557GCKMore
Adenosine-phosphatehsa04960Aldosterone-regulated sodium reabsorption7.59E-032O00141, P06213SGK, INSRMore
Adenosine-phosphatehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Adenosine-phosphatehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Adenosine-phosphatehsa04970Salivary secretion2.76E-056P07550, Q08828, P22694, Q14643, P0DP23, P49913ADRB2, ADCY1, PRKACB, ITPR1, CALM1, CAMPMore
Adenosine-phosphatehsa04971Gastric acid secretion1.74E-035Q08828, P51828, P15311, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM1, CAMK2DMore
Adenosine-phosphatehsa04979Cholesterol metabolism6.61E-033Q5SW96, P38571, P61916LDLRAP1, LIPA, NPC2More
Adenosine-phosphatehsa05010Alzheimer disease4.33E-0316O15239, O95298, P19404, P05496, P13073, P12074, Q00535, O75460, P0DP23, P01584, P18848, Q71U36, Q13509, P05141, P21796, P45880NDUFA1, NDUFC2, NDUFV2, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, CALM1, IL1B, ATF4, TUBA1A, TUBB3, SLC25A5, VDAC1, VDAC2More
Adenosine-phosphatehsa05012Parkinson disease1.47E-0517P62987, O15239, O95298, P19404, P13073, P12074, P05496, P05141, P21796, P45880, O75460, P18848, P19174, P0DP23, Q13557, Q71U36, Q13509UBA52, NDUFA1, NDUFC2, NDUFV2, COX4I1, COX6A1, ATP5G1, SLC25A5, VDAC1, VDAC2, ERN1, ATF4, PLCG1, CALM1, CAMK2D, TUBA1A, TUBB3More
Adenosine-phosphatehsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Adenosine-phosphatehsa05016Huntington disease1.16E-0316O15239, O95298, P19404, P13073, P12074, P05496, Q13547, P24928, P30876, P62487, P05141, P21796, P45880, O75460, Q71U36, Q13509NDUFA1, NDUFC2, NDUFV2, COX4I1, COX6A1, ATP5G1, HDAC1, POLR2A, POLR2B, POLR2G, SLC25A5, VDAC1, VDAC2, ERN1, TUBA1A, TUBB3More
Adenosine-phosphatehsa05017Spinocerebellar ataxia1.93E-035Q92915, Q8TB72, O15399, P42338, P21796FGF14, PUM2, GRIN2D, PIK3CB, VDAC1More
Adenosine-phosphatehsa05020Prion disease9.64E-0310P11142, P19404, P13073, P18848, P05141, P21796, P45880, Q71U36, Q13509, Q99941HSPA8, NDUFV2, COX4I1, ATF4, SLC25A5, VDAC1, VDAC2, TUBA1A, TUBB3, CREBL1More
Adenosine-phosphatehsa05022Pathways of neurodegeneration - multiple diseases1.68E-0421Q71U36, Q13509, O15239, O95298, P19404, P13073, P12074, P05496, Q8TEV9, P21796, O75460, P18848, P19174, P05141, P45880, P20333, Q00535, P01584, P0DP23, Q13557, P62987TUBA1A, TUBB3, NDUFA1, NDUFC2, NDUFV2, COX4I1, COX6A1, ATP5G1, SMCR8, VDAC1, ERN1, ATF4, PLCG1, SLC25A5, VDAC2, TNFRSF1B, CDK5, IL1B, CALM1, CAMK2D, UBA52More
Adenosine-phosphatehsa05030Cocaine addiction4.44E-033P22694, Q99941, P18848PRKACB, CREBL1, ATF4More
Adenosine-phosphatehsa05031Amphetamine addiction1.49E-045P0DP23, Q13557, Q99941, P18848, Q13547CALM1, CAMK2D, CREBL1, ATF4, HDAC1More
Adenosine-phosphatehsa05034Alcoholism1.27E-027Q99941, P18848, Q13547, P0DP23, P62873, P63218, O60814CREBL1, ATF4, HDAC1, CALM1, GNB1, GNG5, H2BC12More
Adenosine-phosphatehsa05110Vibrio cholerae infection2.11E-032Q99437, P17612ATP6V0B, PRKACAMore
Adenosine-phosphatehsa05120Epithelial cell signaling in Helicobacter pylori infection5.36E-056Q16539, Q99437, P09341, P25024, P25025, P41240MAPK14, ATP6V0B, CXCL1, CXCR1, CXCR2, CSKMore
Adenosine-phosphatehsa05133Pertussis8.35E-053P05107, P10145, P0C0L4ITGB2, IL8, C4AMore
Adenosine-phosphatehsa05134Legionellosis3.35E-024P11215, P68104, P11142, P19875ITGAM, EEF1A1, HSPA8, CXCL2More
Adenosine-phosphatehsa05140Leishmaniasis2.69E-025O75015, P13765, O60603, P49006, Q16539FCGR3B, HLA-DOB, TLR2, MARCKSL1, MAPK14More
Adenosine-phosphatehsa05143African trypanosomiasis4.74E-054P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Adenosine-phosphatehsa05144Malaria1.48E-055P69905, P68871, O60603, P05107, P10145HBA2, HBB, TLR2, ITGB2, IL8More
Adenosine-phosphatehsa05146Amoebiasis1.25E-049P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSGMore
Adenosine-phosphatehsa05150Staphylococcus aureus infection1.33E-0612P0C0L4, P21730, P21462, O75015, P13765, P13646, Q14532, P05107, P59665, P59666, P12838, P49913C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, KRT13, KRT32, ITGB2, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Adenosine-phosphatehsa05152Tuberculosis1.95E-025P48382, P10415, P13765, Q9UDY8, P51617RFX5, BCL2, HLA-DOB, MALT1, IRAK1More
Adenosine-phosphatehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Adenosine-phosphatehsa05161Hepatitis B3.34E-023Q99941, P18848, P27348CREBL1, ATF4, YWHAQMore
Adenosine-phosphatehsa05162Measles8.38E-034P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Adenosine-phosphatehsa05163Human cytomegalovirus infection1.27E-0515P01375, P50151, Q14643, P0DP23, Q8NHW4, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, P04637, O00463TNF, GNG10, ITPR1, CALM1, CCL4L2, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, TP53, TRAF5More
Adenosine-phosphatehsa05165Human papillomavirus infection9.48E-048P46527, P35443, P01375, Q08999, Q9UM47, P22694, Q13362, Q13315CDKN1B, THBS4, TNF, RBL2, NOTCH3, PRKACB, PPP2R5C, ATMMore
Adenosine-phosphatehsa05166Human T-cell leukemia virus 1 infection4.93E-026P22694, P18848, P25963, P25208, Q13315, P01375PRKACB, ATF4, NFKBIA, NFYB, ATM, TNFMore
Adenosine-phosphatehsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-027P42224, P62873, P63218, P19875, P19174, P07948, P0DP23STAT1, GNB1, GNG5, CXCL2, PLCG1, LYN, CALM1More
Adenosine-phosphatehsa05169Epstein-Barr virus infection4.48E-039Q13547, P42338, P07948, P30101, Q13761, O75293, P30279, P42224, P07766HDAC1, PIK3CB, LYN, PDIA3, RUNX3, GADD45B, CCND2, STAT1, CD3EMore
Adenosine-phosphatehsa05171Coronavirus disease - COVID-193.18E-037P01584, P62753, P36578, P62888, P61927, P61513, P62829IL1B, RPS6, RPL4, RPL30, RPL37, RPL37A, RPL23More
Adenosine-phosphatehsa05200Pathways in cancer1.83E-0419Q16363, P07900, P08238, P42224, P19174, P43246, Q13485, P20585, P52701, Q13547, P30279, P62873, P63218, P78417, O75293, P0DP23, Q13557, P14784, P01042LAMA4, HSP90AA1, HSP90AB1, STAT1, PLCG1, MSH2, SMAD4, MSH3, MSH6, HDAC1, CCND2, GNB1, GNG5, GSTO1, GADD45B, CALM1, CAMK2D, IL2RB, KNG1More
Adenosine-phosphatehsa05202Transcriptional misregulation in cancer2.64E-1024Q12778, Q15532, Q13315, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P46527, P04637, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P68431, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, CDKN1B, TP53, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, HDAC2, LYL1, GADD45AMore
Adenosine-phosphatehsa05203Viral carcinogenesis5.01E-0616Q08999, Q99941, P18848, P06746, P07948, P30279, P27348, P29083, Q7KZF4, P46527, Q13547, P06396, P25963, P61978, P22694, O60814RBL2, CREBL1, ATF4, POLB, LYN, CCND2, YWHAQ, GTF2E1, SND1, CDKN1B, HDAC1, GSN, NFKBIA, HNRPK, PRKACB, H2BC12More
Adenosine-phosphatehsa05206MicroRNAs in cancer1.67E-024P46527, Q9UM47, P35226, Q13315CDKN1B, NOTCH3, BMI1, ATMMore
Adenosine-phosphatehsa05210Colorectal cancer4.94E-022Q13485, P52701SMAD4, MSH6More
Adenosine-phosphatehsa05214Glioma1.76E-024P0DP23, Q13557, P19174, O75293CALM1, CAMK2D, PLCG1, GADD45BMore
Adenosine-phosphatehsa05217Basal cell carcinoma3.30E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Adenosine-phosphatehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Adenosine-phosphatehsa05221Acute myeloid leukemia3.29E-023P14923, Q15744, P05164JUP, CEBPE, MPOMore
Adenosine-phosphatehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Adenosine-phosphatehsa05226Gastric cancer2.94E-022P04628, P10826WNT1, RARBMore
Adenosine-phosphatehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer3.48E-059O95267, P07766, P20963, P09693, P06239, O60603, Q04759, Q16539, P01730RASGRP1, CD3E, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14, CD4More
Adenosine-phosphatehsa05310Asthma4.06E-043P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Adenosine-phosphatehsa05321Inflammatory bowel disease2.56E-047O60603, P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Adenosine-phosphatehsa05322Systemic lupus erythematosus4.51E-026O75015, P08246, P08311, P01375, P10747, P13765FCGR3B, ELA2, CTSG, TNF, CD28, HLA-DOBMore
Adenosine-phosphatehsa05323Rheumatoid arthritis2.62E-024P01375, P13765, P10747, P09341TNF, HLA-DOB, CD28, CXCL1More
Adenosine-phosphatehsa05330Allograft rejection2.06E-044P13765, P48023, P10747, P01375HLA-DOB, FASLG, CD28, TNFMore
Adenosine-phosphatehsa05332Graft-versus-host disease5.75E-056P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Adenosine-phosphatehsa05410Hypertrophic cardiomyopathy2.60E-022P26012, P09493ITGB8, TPM1More
Adenosine-phosphatehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Adenosine-phosphatehsa05415Diabetic cardiomyopathy5.24E-0312P17252, Q15080, O15239, Q16718, O95298, O14521, P05496, P12074, Q16539, P49841, Q13557, P14780PRKCA, NCF4, NDUFA1, NDUFA5, NDUFC2, SDHD, ATP5G1, COX6A1, MAPK14, GSK3B, CAMK2D, MMP9More
Adenosine-phosphatehsa05418Fluid shear stress and atherosclerosis1.26E-048Q16539, Q14145, P10599, P14780, P01375, P04637, P14778, P27930MAPK14, KEAP1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2More

Community members of Adenosine-phosphate (SDC: 5.76)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
PRKAB1Q9Y478Kd3700