PharmaCoNets of Acetyl-sulfisoxazole (SPCN: 31.20 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Acetyl-sulfisoxazolehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Acetyl-sulfisoxazolehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Acetyl-sulfisoxazolehsa01524Platinum drug resistance4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Acetyl-sulfisoxazolehsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Acetyl-sulfisoxazolehsa04014Ras signaling pathway7.30E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04015Rap1 signaling pathway6.14E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04022cGMP-PKG signaling pathway5.07E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04024cAMP signaling pathway3.23E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04071Sphingolipid signaling pathway9.70E-047P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Acetyl-sulfisoxazolehsa04140Autophagy - animal3.72E-025P22694, Q14643, P10415, Q9H1Y0, Q04759PRKACB, ITPR1, BCL2, ATG5, PRKCQMore
Acetyl-sulfisoxazolehsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Acetyl-sulfisoxazolehsa04218Cellular senescence3.65E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04261Adrenergic signaling in cardiomyocytes4.57E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04370VEGF signaling pathway3.60E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04371Apelin signaling pathway3.23E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04380Osteoclast differentiation2.11E-032Q9NQC7, P31751CYLD, AKT2More
Acetyl-sulfisoxazolehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Acetyl-sulfisoxazolehsa04612Antigen processing and presentation2.84E-027P13765, P48382, P26715, P26717, Q13241, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Acetyl-sulfisoxazolehsa04613Neutrophil extracellular trap formation1.32E-0314O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Acetyl-sulfisoxazolehsa04620Toll-like receptor signaling pathway4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04622RIG-I-like receptor signaling pathway1.81E-021Q9NQC7CYLDMore
Acetyl-sulfisoxazolehsa04625C-type lectin receptor signaling pathway1.38E-053Q9NQC7, P31751, P0DP23CYLD, AKT2, CALM1More
Acetyl-sulfisoxazolehsa04640Hematopoietic cell lineage3.58E-028P13612, P27930, P15144, P25063, P09693, P01732, P13765, P01375ITGA4, IL1R2, ANPEP, CD24, CD3G, CD8A, HLA-DOB, TNFMore
Acetyl-sulfisoxazolehsa04657IL-17 signaling pathway4.98E-026O00463, Q16539, P14780, Q9UJX4, P80188, P01375TRAF5, MAPK14, MMP9, ANAPC5, LCN2, TNFMore
Acetyl-sulfisoxazolehsa04658Th1 and Th2 cell differentiation1.48E-027Q04759, P20963, P09693, Q14765, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, STAT4, GATA3, TBX21, HLA-DOBMore
Acetyl-sulfisoxazolehsa04660T cell receptor signaling pathway3.19E-0310P01375, Q9UDY8, Q04759, P10747, O95267, Q08881, P20963, P09693, P01732, Q13191TNF, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD247, CD3G, CD8A, CBLBMore
Acetyl-sulfisoxazolehsa04662B cell receptor signaling pathway4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04664Fc epsilon RI signaling pathway4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04672Intestinal immune network for IgA production1.66E-023P10747, P13765, P13612CD28, HLA-DOB, ITGA4More
Acetyl-sulfisoxazolehsa04722Neurotrophin signaling pathway2.83E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04728Dopaminergic synapse3.23E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04740Olfactory transduction2.41E-021P0DP23CALM1More
Acetyl-sulfisoxazolehsa04744Phototransduction1.81E-021P0DP23CALM1More
Acetyl-sulfisoxazolehsa04910Insulin signaling pathway9.82E-042P0DP23, P31751CALM1, AKT2More
Acetyl-sulfisoxazolehsa04915Estrogen signaling pathway5.07E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04916Melanogenesis4.78E-021P0DP23CALM1More
Acetyl-sulfisoxazolehsa04917Prolactin signaling pathway2.41E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04920Adipocytokine signaling pathway4.19E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04922Glucagon signaling pathway1.79E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa04923Regulation of lipolysis in adipocytes3.01E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04924Renin secretion1.03E-024P22694, P07550, Q14643, P0DP23PRKACB, ADRB2, ITPR1, CALM1More
Acetyl-sulfisoxazolehsa04927Cortisol synthesis and secretion1.66E-023Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Acetyl-sulfisoxazolehsa04929GnRH secretion1.81E-021P31751AKT2More
Acetyl-sulfisoxazolehsa04940Type I diabetes mellitus3.64E-023P10747, P13765, P01375CD28, HLA-DOB, TNFMore
Acetyl-sulfisoxazolehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Acetyl-sulfisoxazolehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Acetyl-sulfisoxazolehsa04970Salivary secretion1.31E-025P07550, P22694, Q14643, P0DP23, P49913ADRB2, PRKACB, ITPR1, CALM1, CAMPMore
Acetyl-sulfisoxazolehsa04971Gastric acid secretion4.78E-021P0DP23CALM1More
Acetyl-sulfisoxazolehsa04973Carbohydrate digestion and absorption2.41E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05010Alzheimer disease8.59E-043Q00535, P0DP23, P31751CDK5, CALM1, AKT2More
Acetyl-sulfisoxazolehsa05022Pathways of neurodegeneration - multiple diseases2.95E-022Q00535, P0DP23CDK5, CALM1More
Acetyl-sulfisoxazolehsa05030Cocaine addiction4.19E-021Q00535CDK5More
Acetyl-sulfisoxazolehsa05031Amphetamine addiction4.78E-021P0DP23CALM1More
Acetyl-sulfisoxazolehsa05133Pertussis4.20E-021P0C0L4C4AMore
Acetyl-sulfisoxazolehsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Acetyl-sulfisoxazolehsa05144Malaria6.79E-036P69905, P68871, O60603, P01375, P35443, P26718HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Acetyl-sulfisoxazolehsa05146Amoebiasis1.48E-027P09341, P27930, P01375, O60603, P05089, P22694, P08311CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSGMore
Acetyl-sulfisoxazolehsa05152Tuberculosis9.92E-032P0DP23, P31751CALM1, AKT2More
Acetyl-sulfisoxazolehsa05163Human cytomegalovirus infection1.21E-022P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa05167Kaposi sarcoma-associated herpesvirus infection5.07E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa05170Human immunodeficiency virus 1 infection6.71E-032P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa05200Pathways in cancer3.07E-022P31751, P0DP23AKT2, CALM1More
Acetyl-sulfisoxazolehsa05202Transcriptional misregulation in cancer1.78E-0316Q15532, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, LYL1, GADD45AMore
Acetyl-sulfisoxazolehsa05211Renal cell carcinoma4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05212Pancreatic cancer4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05213Endometrial cancer3.60E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05214Glioma5.75E-042P0DP23, P31751CALM1, AKT2More
Acetyl-sulfisoxazolehsa05218Melanoma3.01E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05220Chronic myeloid leukemia4.19E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05221Acute myeloid leukemia4.19E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05222Small cell lung cancer4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05223Non-small cell lung cancer2.41E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05226Gastric cancer3.60E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05230Central carbon metabolism in cancer4.78E-021P31751AKT2More
Acetyl-sulfisoxazolehsa05310Asthma1.66E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Acetyl-sulfisoxazolehsa05321Inflammatory bowel disease1.14E-036O60603, P01375, P13765, Q14765, Q9UL17, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3More
Acetyl-sulfisoxazolehsa05323Rheumatoid arthritis1.58E-025P01375, P13765, P10747, P09341, O60603TNF, HLA-DOB, CD28, CXCL1, TLR2More
Acetyl-sulfisoxazolehsa05332Graft-versus-host disease2.03E-035P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Acetyl-sulfisoxazolehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Acetyl-sulfisoxazolehsa05418Fluid shear stress and atherosclerosis3.65E-032P31751, P0DP23AKT2, CALM1More

Community members of Acetyl-sulfisoxazole (SDC: 3.07)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)