PharmaCoNets of Acetophenazine (SPCN: 15.74 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Acetophenazinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Acetophenazinehsa00220Arginine biosynthesis1.97E-022P15104, P49448GLUL, GLUD2More
Acetophenazinehsa00250Alanine, aspartate and glutamate metabolism1.97E-022P49448, P15104GLUD2, GLULMore
Acetophenazinehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Acetophenazinehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Acetophenazinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Acetophenazinehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Acetophenazinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Acetophenazinehsa00910Nitrogen metabolism1.97E-022P15104, P49448GLUL, GLUD2More
Acetophenazinehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Acetophenazinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Acetophenazinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Acetophenazinehsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Acetophenazinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Acetophenazinehsa04151PI3K-Akt signaling pathway3.96E-028P43657, P09603, Q9GZP0, P63218, P50151, P13612, O15335, Q13751P2RY5, CSF1, PDGFD, GNG5, GNG10, ITGA4, CHAD, LAMB3More
Acetophenazinehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Acetophenazinehsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Acetophenazinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Acetophenazinehsa04512ECM-receptor interaction4.41E-023Q13751, P13612, O15335LAMB3, ITGA4, CHADMore
Acetophenazinehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Acetophenazinehsa04613Neutrophil extracellular trap formation1.73E-024Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Acetophenazinehsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Acetophenazinehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Acetophenazinehsa04724Glutamatergic synapse9.51E-034O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Acetophenazinehsa04727GABAergic synapse2.33E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Acetophenazinehsa04730Long-term depression3.72E-022Q14344, P07948GNA13, LYNMore
Acetophenazinehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Acetophenazinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Acetophenazinehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Acetophenazinehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Acetophenazinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Acetophenazinehsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Acetophenazinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Acetophenazinehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Acetophenazinehsa05010Alzheimer disease4.39E-026O15399, Q9NZJ5, Q13564, Q71U36, P09603, P21796GRIN2D, EIF2AK3, APPBP1, TUBA1A, CSF1, VDAC1More
Acetophenazinehsa05032Morphine addiction1.34E-024P63218, P50151, Q07343, P43250GNG5, GNG10, PDE4B, GRK6More
Acetophenazinehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Acetophenazinehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Acetophenazinehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Acetophenazinehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Acetophenazinehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Acetophenazinehsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Acetophenazinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Acetophenazinehsa05332Graft-versus-host disease3.70E-022P48023, P01375FASLG, TNFMore

Community members of Acetophenazine (SDC: 3.66)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorReported00.060410.47792.5081
P61088UBE2NUbiquitinNoneconjugating enzyme E2 NPredicted00.11020.38250.37361.1937
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)