PharmaCoNets of 2-mercaptobenzothiazole (SPCN: 4.65 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
2-mercaptobenzothiazolehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
2-mercaptobenzothiazolehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
2-mercaptobenzothiazolehsa00983Drug metabolism - other enzymes3.50E-023P04183, P32320, P05164TK1, CDA, MPOMore
2-mercaptobenzothiazolehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
2-mercaptobenzothiazolehsa04064NF-kappa B signaling pathway1.60E-028P10415, O00463, Q04759, Q9UDY8, Q16548, Q13315, P24522, P09341BCL2, TRAF5, PRKCQ, MALT1, BCL2A1, ATM, GADD45A, CXCL1More
2-mercaptobenzothiazolehsa04071Sphingolipid signaling pathway2.96E-025P21453, Q9H228, Q13362, Q9BX95, P10415S1PR1, EDG8, PPP2R5C, SGPP1, BCL2More
2-mercaptobenzothiazolehsa04080Neuroactive ligand-receptor interaction3.22E-027P08311, Q15722, P21453, Q9H228, O00398, P21730, Q16581CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, C3AR1More
2-mercaptobenzothiazolehsa04115p53 signaling pathway3.98E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
2-mercaptobenzothiazolehsa04210Apoptosis3.77E-028Q13315, P10415, O76075, P24522, Q16548, P43234, P18848, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ATF4, ITPR1More
2-mercaptobenzothiazolehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
2-mercaptobenzothiazolehsa04612Antigen processing and presentation3.21E-026P13765, P48382, P26715, P26717, Q13241, P01732HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8AMore
2-mercaptobenzothiazolehsa04725Cholinergic synapse4.83E-024P22694, Q14643, P18848, P10415PRKACB, ITPR1, ATF4, BCL2More
2-mercaptobenzothiazolehsa04915Estrogen signaling pathway2.96E-025P14780, P22694, P18848, Q14643, P10415MMP9, PRKACB, ATF4, ITPR1, BCL2More
2-mercaptobenzothiazolehsa04918Thyroid hormone synthesis3.50E-023P22694, P18848, Q14643PRKACB, ATF4, ITPR1More
2-mercaptobenzothiazolehsa04927Cortisol synthesis and secretion8.60E-033Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
2-mercaptobenzothiazolehsa04928Parathyroid hormone synthesis, secretion and action2.13E-025Q14643, P22694, P23771, P18848, P10415ITPR1, PRKACB, GATA3, ATF4, BCL2More
2-mercaptobenzothiazolehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
2-mercaptobenzothiazolehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
2-mercaptobenzothiazolehsa05133Pertussis4.20E-021P0C0L4C4AMore
2-mercaptobenzothiazolehsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
2-mercaptobenzothiazolehsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
2-mercaptobenzothiazolehsa05202Transcriptional misregulation in cancer1.77E-0211Q15532, Q13315, P14780, Q15744, Q16548, O15550, P05164, P12838, P08246, Q9C0K0, P24522SS18, ATM, MMP9, CEBPE, BCL2A1, UTX, MPO, DEFA4, ELA2, BCL11B, GADD45AMore
2-mercaptobenzothiazolehsa05321Inflammatory bowel disease2.29E-024P13765, Q14765, P23771, Q9HBE5HLA-DOB, STAT4, GATA3, IL21RMore
2-mercaptobenzothiazolehsa05332Graft-versus-host disease7.89E-034P13765, P10747, P26715, Q13241HLA-DOB, CD28, KLRC1, KLRD1More
2-mercaptobenzothiazolehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More

Community members of 2-mercaptobenzothiazole (SDC: 1.89)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)